assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	1	1940717-1940796	1	CRISPRCasFinder	no		cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Orphan	GACCGCGGCGCGCGGAACGGCCCCGG	26	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA|235aa|up_5|CP029607.1_1932983_1933688_+,NA|126aa|up_1|CP029607.1_1938370_1938748_+,NA|72aa|down_7|CP029607.1_1953985_1954201_+,NA|388aa|down_8|CP029607.1_1954239_1955403_+	NA|743aa|up_9|CP029607.1_1927547_1929776_+	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]	NA|282aa|up_8|CP029607.1_1929946_1930792_-	cd00317, cyclophilin, cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases	NA|235aa|up_7|CP029607.1_1931007_1931712_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|422aa|up_6|CP029607.1_1931721_1932987_+	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed	NA|235aa|up_5|CP029607.1_1932983_1933688_+	NA	NA|319aa|up_4|CP029607.1_1934568_1935525_-	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism]	NA|535aa|up_3|CP029607.1_1935806_1937411_-	pfam07907, YibE_F, YibE/F-like protein	NA|286aa|up_2|CP029607.1_1937399_1938257_+	smart00306, HintN, Hint (Hedgehog/Intein) domain N-terminal region	NA|126aa|up_1|CP029607.1_1938370_1938748_+	NA	NA|196aa|up_0|CP029607.1_1938888_1939476_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|532aa|down_0|CP029607.1_1942519_1944115_+	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain	NA|679aa|down_1|CP029607.1_1944116_1946153_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|387aa|down_2|CP029607.1_1946149_1947310_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|312aa|down_3|CP029607.1_1947350_1948286_-	PRK13355, PRK13355, bifunctional HTH-domain containing protein/aminotransferase; Provisional	NA|382aa|down_4|CP029607.1_1949154_1950300_+	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins	NA|398aa|down_5|CP029607.1_1950566_1951760_+	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins	NA|593aa|down_6|CP029607.1_1951934_1953713_+	PRK00476, aspS, aspartyl-tRNA synthetase; Validated	NA|72aa|down_7|CP029607.1_1953985_1954201_+	NA	NA|388aa|down_8|CP029607.1_1954239_1955403_+	NA	NA|405aa|down_9|CP029607.1_1955656_1956871_-	cd04188, DPG_synthase, DPG_synthase is involved in protein N-linked glycosylation
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	2	3784031-3784114	2	CRISPRCasFinder	no		cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Orphan	GCTCTCGGATCGGATCGCGACAC	23	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA|249aa|up_8|CP029607.1_3775192_3775939_-,NA|209aa|up_4|CP029607.1_3781144_3781771_+,NA|118aa|up_3|CP029607.1_3781857_3782211_+,NA|66aa|up_2|CP029607.1_3782334_3782532_-,NA|128aa|up_1|CP029607.1_3782754_3783138_+,NA|238aa|up_0|CP029607.1_3783267_3783981_+,NA|192aa|down_5|CP029607.1_3789993_3790569_-	NA|405aa|up_9|CP029607.1_3773981_3775196_-	COG2856, COG2856, Predicted Zn peptidase [Amino acid transport and metabolism]	NA|249aa|up_8|CP029607.1_3775192_3775939_-	NA	NA|739aa|up_7|CP029607.1_3776195_3778412_+	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only]	NA|266aa|up_6|CP029607.1_3778541_3779339_+	cd01833, XynB_like, SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB	NA|115aa|up_5|CP029607.1_3779450_3779795_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|209aa|up_4|CP029607.1_3781144_3781771_+	NA	NA|118aa|up_3|CP029607.1_3781857_3782211_+	NA	NA|66aa|up_2|CP029607.1_3782334_3782532_-	NA	NA|128aa|up_1|CP029607.1_3782754_3783138_+	NA	NA|238aa|up_0|CP029607.1_3783267_3783981_+	NA	NA|294aa|down_0|CP029607.1_3784273_3785155_-	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases	NA|199aa|down_1|CP029607.1_3785225_3785822_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|74aa|down_2|CP029607.1_3786118_3786340_+	pfam17195, DUF5132, Protein of unknown function (DUF5132)	NA|751aa|down_3|CP029607.1_3786383_3788636_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|417aa|down_4|CP029607.1_3788644_3789895_+	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional	NA|192aa|down_5|CP029607.1_3789993_3790569_-	NA	NA|349aa|down_6|CP029607.1_3790813_3791860_-	pfam00891, Methyltransf_2, O-methyltransferase	NA|1059aa|down_7|CP029607.1_3792049_3795226_+	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|1598aa|down_8|CP029607.1_3795436_3800230_+	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|3340aa|down_9|CP029607.1_3800239_3810259_+	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	3	3827722-3827811	3	CRISPRCasFinder	no		cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Orphan	GTCCGGGCCGACGATCCCGCGTGGGG	26	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA,NA|53aa|down_4|CP029607.1_3853112_3853271_-	NA|332aa|up_9|CP029607.1_3815152_3816148_+	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]	NA|91aa|up_8|CP029607.1_3816144_3816417_+	COG0236, AcpP, Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|431aa|up_7|CP029607.1_3817608_3818901_+	TIGR01686, modular_polyketide_synthase, FkbH-like domain	NA|221aa|up_6|CP029607.1_3818893_3819556_+	pfam01596, Methyltransf_3, O-methyltransferase	NA|903aa|up_5|CP029607.1_3819784_3822493_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|379aa|up_4|CP029607.1_3822518_3823655_+	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism]	NA|116aa|up_3|CP029607.1_3823669_3824017_-	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown]	NA|675aa|up_2|CP029607.1_3824234_3826259_+	COG2192, COG2192, Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]	NA|122aa|up_1|CP029607.1_3826654_3827020_+	pfam11080, GhoS, Endoribonuclease GhoS	NA|62aa|up_0|CP029607.1_3827396_3827582_+	pfam13586, DDE_Tnp_1_2, Transposase DDE domain	NA|145aa|down_0|CP029607.1_3827987_3828422_-	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase	NA|389aa|down_1|CP029607.1_3828642_3829809_+	pfam01041, DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase family	NA|4576aa|down_2|CP029607.1_3829997_3843725_+	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|3143aa|down_3|CP029607.1_3843721_3853150_+	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|53aa|down_4|CP029607.1_3853112_3853271_-	NA	NA|403aa|down_5|CP029607.1_3853226_3854435_+	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins	NA|342aa|down_6|CP029607.1_3854702_3855728_+	cd05360, SDR_c3, classical (c) SDR, subgroup 3	NA|155aa|down_7|CP029607.1_3855807_3856272_-	pfam14325, DUF4383, Domain of unknown function (DUF4383)	NA|207aa|down_8|CP029607.1_3856453_3857074_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|192aa|down_9|CP029607.1_3857116_3857692_+	pfam00067, p450, Cytochrome P450
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	5	6450536-6451111	4	CRISPRCasFinder	no		cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Orphan	GACGGTTGAACGGACCGTTCAACCG	25	0	0	NA	NA	NA	11	11	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA,NA|55aa|down_6|CP029607.1_6458197_6458362_+	NA|219aa|up_9|CP029607.1_6442992_6443649_+	COG2977, EntD, Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|494aa|up_8|CP029607.1_6443718_6445200_+	PRK13517, PRK13517, glutamate--cysteine ligase	NA|279aa|up_7|CP029607.1_6445316_6446153_-	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|128aa|up_6|CP029607.1_6446296_6446680_+	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|110aa|up_5|CP029607.1_6446676_6447006_-	cd19534, E_NRPS, Epimerization domain of nonribosomal peptide synthetases (NRPSs); belongs to the Condensation-domain family	NA|136aa|up_4|CP029607.1_6447209_6447617_-	cd17036, T3SC_YbjN-like_1, T110839 is structurally similar to type III secretion system chaperones and YbjN family proteins	NA|225aa|up_3|CP029607.1_6447616_6448291_-	pfam06197, DUF998, Protein of unknown function (DUF998)	NA|191aa|up_2|CP029607.1_6448360_6448933_-	PRK03759, PRK03759, isopentenyl-diphosphate Delta-isomerase	NA|186aa|up_1|CP029607.1_6448987_6449545_-	PRK14996, PRK14996, TetR family transcriptional regulator; Provisional	NA|280aa|up_0|CP029607.1_6449633_6450473_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|325aa|down_0|CP029607.1_6451346_6452321_-	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|310aa|down_1|CP029607.1_6452414_6453344_+	pfam12852, Cupin_6, Cupin	NA|139aa|down_2|CP029607.1_6454222_6454639_+	pfam14430, Imm1, Immunity protein Imm1	NA|253aa|down_3|CP029607.1_6454717_6455476_-	pfam18181, SLATT_1, SMODS and SLOG-associating 2TM effector domain 1	NA|399aa|down_4|CP029607.1_6455472_6456669_-	pfam18171, LSDAT_prok, SLOG in TRPM, prokaryote	NA|464aa|down_5|CP029607.1_6456842_6458234_+	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|55aa|down_6|CP029607.1_6458197_6458362_+	NA	NA|1154aa|down_7|CP029607.1_6458321_6461783_+	TIGR03491, TIGR03491, RecB family nuclease, putative, TM0106 family	NA|217aa|down_8|CP029607.1_6462462_6463113_+	COG3889, COG3889, Predicted solute binding protein [General function prediction only]	NA|326aa|down_9|CP029607.1_6463279_6464257_-	cd08234, threonine_DH_like, L-threonine dehydrogenase
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	6	6529189-6529275	5	CRISPRCasFinder	no	csa3	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Type I-A	CGGGGCGTCGGGCCGGGGGCCTCGGGCCGGGG	32	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA|67aa|up_9|CP029607.1_6518919_6519120_+,NA|69aa|down_0|CP029607.1_6529356_6529563_-	NA|67aa|up_9|CP029607.1_6518919_6519120_+	NA	csa3|300aa|up_8|CP029607.1_6519123_6520023_-	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors	NA|397aa|up_7|CP029607.1_6520095_6521286_+	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|963aa|up_6|CP029607.1_6521364_6524253_-	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|189aa|up_5|CP029607.1_6524736_6525303_-	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|158aa|up_4|CP029607.1_6525687_6526161_-	pfam02577, DNase-RNase, Bifunctional nuclease	NA|314aa|up_3|CP029607.1_6526306_6527248_-	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|151aa|up_2|CP029607.1_6527281_6527734_-	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms]	NA|127aa|up_1|CP029607.1_6527847_6528228_-	PRK01202, PRK01202, glycine cleavage system protein GcvH	NA|204aa|up_0|CP029607.1_6528286_6528898_-	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism]	NA|69aa|down_0|CP029607.1_6529356_6529563_-	NA	NA|139aa|down_1|CP029607.1_6529978_6530395_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|266aa|down_2|CP029607.1_6530345_6531143_-	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain	NA|146aa|down_3|CP029607.1_6531301_6531739_+	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|269aa|down_4|CP029607.1_6531735_6532542_+	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|100aa|down_5|CP029607.1_6532726_6533026_+	pfam02467, Whib, Transcription factor WhiB	NA|289aa|down_6|CP029607.1_6533189_6534056_-	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|210aa|down_7|CP029607.1_6534200_6534830_-	pfam13398, Peptidase_M50B, Peptidase M50B-like	NA|294aa|down_8|CP029607.1_6535014_6535896_+	cd19752, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein	NA|246aa|down_9|CP029607.1_6536000_6536738_-	pfam14325, DUF4383, Domain of unknown function (DUF4383)
GCA_003516205.1_ASM351620v1	CP029607	Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 chromosome, complete genome	7	6963017-6963123	6	CRISPRCasFinder	no		cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	Orphan	GCCGCCGGGGCCTTGGGGGCCTGC	24	0	0	NA	NA	NA	1	1	Orphan	cas3,DinG,DEDDh,csa3,cas4,WYL,cas6e,RT	NA|67aa|up_7|CP029607.1_6954326_6954527_-,NA|62aa|down_0|CP029607.1_6963207_6963393_+	NA|160aa|up_9|CP029607.1_6952590_6953070_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|294aa|up_8|CP029607.1_6953170_6954052_-	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase	NA|67aa|up_7|CP029607.1_6954326_6954527_-	NA	NA|300aa|up_6|CP029607.1_6954712_6955612_-	PRK03287, truB, tRNA pseudouridine synthase B; Provisional	NA|440aa|up_5|CP029607.1_6955684_6957004_-	cd06174, MFS, Major Facilitator Superfamily	NA|434aa|up_4|CP029607.1_6957095_6958397_-	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins	NA|337aa|up_3|CP029607.1_6958484_6959495_-	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only]	NA|150aa|up_2|CP029607.1_6959505_6959955_-	PRK00521, rbfA, 30S ribosome-binding factor RbfA	NA|99aa|up_1|CP029607.1_6959974_6960271_-	pfam04456, DUF503, Protein of unknown function (DUF503)	NA|845aa|up_0|CP029607.1_6960369_6962904_-	PRK05306, infB, translation initiation factor IF-2; Validated	NA|62aa|down_0|CP029607.1_6963207_6963393_+	NA	NA|338aa|down_1|CP029607.1_6963926_6964940_-	PRK12327, nusA, transcription elongation factor NusA; Provisional	NA|175aa|down_2|CP029607.1_6964936_6965461_-	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed	NA|146aa|down_3|CP029607.1_6965616_6966054_+	PRK11907, PRK11907, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA|147aa|down_4|CP029607.1_6966050_6966491_+	pfam14530, DUF4439, Domain of unknown function (DUF4439)	NA|287aa|down_5|CP029607.1_6966684_6967545_-	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|334aa|down_6|CP029607.1_6967639_6968641_-	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]	NA|263aa|down_7|CP029607.1_6968742_6969531_-	PRK12748, PRK12748, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|136aa|down_8|CP029607.1_6969579_6969987_+	pfam01894, UPF0047, Uncharacterized protein family UPF0047	NA|363aa|down_9|CP029607.1_6970111_6971200_+	PRK14086, dnaA, chromosomal replication initiator protein DnaA
