assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003671995.1_ASM367199v1	CP028460	Bifidobacterium animalis subsp. animalis strain CNCM I-4602 chromosome, complete genome	2	358107-358190	2	CRISPRCasFinder	no		WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	Orphan	CTCGCTCTGCGTAAAAAGGGACA	23	0	0	NA	NA	NA	1	1	Orphan	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	NA,NA|207aa|down_0|CP028460.1_358284_358905_+	NA|185aa|up_9|CP028460.1_348298_348853_-	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed	NA|661aa|up_8|CP028460.1_348868_350851_-	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated	NA|259aa|up_7|CP028460.1_351194_351971_-	PRK00102, rnc, ribonuclease III; Reviewed	NA|65aa|up_6|CP028460.1_352334_352529_-	PRK12286, rpmF, 50S ribosomal protein L32; Reviewed	NA|199aa|up_5|CP028460.1_352607_353204_-	pfam02620, DUF177, Uncharacterized ACR, COG1399	NA|234aa|up_4|CP028460.1_353310_354012_-	cd06503, ATP-synt_Fo_b, F-type ATP synthase, membrane subunit b	NA|160aa|up_3|CP028460.1_354062_354542_-	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional	NA|98aa|up_2|CP028460.1_354717_355011_+	pfam11238, DUF3039, Protein of unknown function (DUF3039)	NA|336aa|up_1|CP028460.1_355092_356100_-	cd19089, AKR_AKR14A1_2, AKR14A family of aldo-keto reductase (AKR)	NA|441aa|up_0|CP028460.1_356178_357501_-	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated	NA|207aa|down_0|CP028460.1_358284_358905_+	NA	NA|247aa|down_1|CP028460.1_359377_360118_+	PRK00173, rph, ribonuclease PH; Reviewed	NA|226aa|down_2|CP028460.1_360146_360824_+	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed	NA|428aa|down_3|CP028460.1_360865_362149_+	pfam02388, FemAB, FemAB family	NA|336aa|down_4|CP028460.1_362178_363186_-	COG0679, COG0679, Predicted permeases [General function prediction only]	NA|404aa|down_5|CP028460.1_363603_364815_+	cd02509, GDP-M1P_Guanylyltransferase, GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose	NA|566aa|down_6|CP028460.1_365104_366802_+	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed	NA|107aa|down_7|CP028460.1_367270_367591_+	pfam01527, HTH_Tnp_1, Transposase	NA|246aa|down_8|CP028460.1_367785_368523_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|122aa|down_9|CP028460.1_368839_369205_+	PRK05338, rplS, 50S ribosomal protein L19; Provisional
GCA_003671995.1_ASM367199v1	CP028460	Bifidobacterium animalis subsp. animalis strain CNCM I-4602 chromosome, complete genome	3	1611410-1611574	1	PILER-CR	no		WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	Orphan	CCCATGCGTAAAAAGGGACATT	22	0	0	NA	NA	NA	2	2	Orphan	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	NA|45aa|up_1|CP028460.1_1607560_1607695_-,NA|150aa|down_7|CP028460.1_1618468_1618918_-	NA|274aa|up_9|CP028460.1_1596809_1597631_-	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]	NA|309aa|up_8|CP028460.1_1597857_1598784_-	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1	NA|387aa|up_7|CP028460.1_1598930_1600091_+	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase	NA|377aa|up_6|CP028460.1_1600516_1601647_-	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain	NA|741aa|up_5|CP028460.1_1602199_1604422_-	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family	NA|254aa|up_4|CP028460.1_1604553_1605315_-	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|388aa|up_3|CP028460.1_1605354_1606518_-	cd16443, LplA, lipoate-protein ligase	NA|155aa|up_2|CP028460.1_1606615_1607080_-	pfam05154, TM2, TM2 domain	NA|45aa|up_1|CP028460.1_1607560_1607695_-	NA	NA|347aa|up_0|CP028460.1_1607770_1608811_-	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional	NA|504aa|down_0|CP028460.1_1611689_1613201_-	pfam09949, DUF2183, Uncharacterized conserved protein (DUF2183)	NA|137aa|down_1|CP028460.1_1613257_1613668_-	PRK01202, PRK01202, glycine cleavage system protein GcvH	NA|370aa|down_2|CP028460.1_1613731_1614841_-	COG2816, NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]	NA|309aa|down_3|CP028460.1_1614840_1615767_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|205aa|down_4|CP028460.1_1615846_1616461_-	pfam16262, DUF4916, Domain of unknown function (DUF4916)	NA|132aa|down_5|CP028460.1_1616646_1617042_+	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains	NA|349aa|down_6|CP028460.1_1617314_1618361_+	COG3583, COG3583, Uncharacterized protein conserved in bacteria [Function unknown]	NA|150aa|down_7|CP028460.1_1618468_1618918_-	NA	NA|631aa|down_8|CP028460.1_1619153_1621046_-	pfam13196, DUF4012, Protein of unknown function (DUF4012)	NA|297aa|down_9|CP028460.1_1621195_1622086_-	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form
GCA_003671995.1_ASM367199v1	CP028460	Bifidobacterium animalis subsp. animalis strain CNCM I-4602 chromosome, complete genome	4	1656401-1657712	3,1,2,3	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	Type I-E	CGGATCATCCCCGCCTGTGCGGGGCAAAC,CGGATCATCCCCGCCTGTGCGGGGCAAAC,CGGATCATCCCCGCCTGTGCGGGGCAAAC,CGGATCATCCCCGCCTGTGCGGGGCAAAC	29,29,29,29	0	0	NA	NA	I-C,I-E,II-B:I-C,I-E,II-B:I-C,I-E,II-B:I-C,I-E,II-B	21,21,17,17	21	TypeI-E	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	NA,NA	NA|453aa|up_9|CP028460.1_1638629_1639988_-	PRK00701, PRK00701, divalent metal cation transporter MntH	NA|243aa|up_8|CP028460.1_1640097_1640826_-	pfam07510, DUF1524, Protein of unknown function (DUF1524)	NA|292aa|up_7|CP028460.1_1640984_1641860_+	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA|217aa|up_6|CP028460.1_1641886_1642537_+	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA|1195aa|up_5|CP028460.1_1642616_1646201_-	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]	NA|607aa|up_4|CP028460.1_1646453_1648274_+	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases	NA|471aa|up_3|CP028460.1_1648344_1649757_-	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|174aa|up_2|CP028460.1_1649956_1650478_+	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase	NA|590aa|up_1|CP028460.1_1650560_1652330_-	pfam13196, DUF4012, Protein of unknown function (DUF4012)	NA|255aa|up_0|CP028460.1_1654901_1655666_+	PRK12704, PRK12704, phosphodiesterase; Provisional	cas1|323aa|down_0|CP028460.1_1658862_1659831_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|225aa|down_1|CP028460.1_1659854_1660529_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|258aa|down_2|CP028460.1_1660531_1661305_-	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|393aa|down_3|CP028460.1_1661307_1662486_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|223aa|down_4|CP028460.1_1662533_1663202_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|562aa|down_5|CP028460.1_1663204_1664890_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|1045aa|down_6|CP028460.1_1664873_1668008_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|328aa|down_7|CP028460.1_1668442_1669426_-	PRK01212, PRK01212, homoserine kinase; Provisional	NA|437aa|down_8|CP028460.1_1669488_1670799_-	PRK06349, PRK06349, homoserine dehydrogenase; Provisional	NA|530aa|down_9|CP028460.1_1671117_1672707_-	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase
GCA_003671995.1_ASM367199v1	CP028460	Bifidobacterium animalis subsp. animalis strain CNCM I-4602 chromosome, complete genome	5	1657789-1658367	4,4,2	PILER-CR,CRISPRCasFinder,CRT	no	cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	Type I-E	CGGATCATCCCCGCCTGTGCGGGGCAAAC,CGGATCATCCCCGCCTGTGCGGGGCAAAC,CGGATCATCCCCGCCTGTGCGGGGCAAAC	29,29,29	0	0	NA	NA	I-C,I-E,II-B:I-C,I-E,II-B:I-C,I-E,II-B	9,9,9	9	TypeI-E	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	NA,NA	NA|453aa|up_9|CP028460.1_1638629_1639988_-	PRK00701, PRK00701, divalent metal cation transporter MntH	NA|243aa|up_8|CP028460.1_1640097_1640826_-	pfam07510, DUF1524, Protein of unknown function (DUF1524)	NA|292aa|up_7|CP028460.1_1640984_1641860_+	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA|217aa|up_6|CP028460.1_1641886_1642537_+	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA|1195aa|up_5|CP028460.1_1642616_1646201_-	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]	NA|607aa|up_4|CP028460.1_1646453_1648274_+	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases	NA|471aa|up_3|CP028460.1_1648344_1649757_-	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|174aa|up_2|CP028460.1_1649956_1650478_+	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase	NA|590aa|up_1|CP028460.1_1650560_1652330_-	pfam13196, DUF4012, Protein of unknown function (DUF4012)	NA|255aa|up_0|CP028460.1_1654901_1655666_+	PRK12704, PRK12704, phosphodiesterase; Provisional	cas1|323aa|down_0|CP028460.1_1658862_1659831_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|225aa|down_1|CP028460.1_1659854_1660529_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|258aa|down_2|CP028460.1_1660531_1661305_-	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|393aa|down_3|CP028460.1_1661307_1662486_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|223aa|down_4|CP028460.1_1662533_1663202_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|562aa|down_5|CP028460.1_1663204_1664890_-	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cas3|1045aa|down_6|CP028460.1_1664873_1668008_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|328aa|down_7|CP028460.1_1668442_1669426_-	PRK01212, PRK01212, homoserine kinase; Provisional	NA|437aa|down_8|CP028460.1_1669488_1670799_-	PRK06349, PRK06349, homoserine dehydrogenase; Provisional	NA|530aa|down_9|CP028460.1_1671117_1672707_-	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase
GCA_003671995.1_ASM367199v1	CP028460	Bifidobacterium animalis subsp. animalis strain CNCM I-4602 chromosome, complete genome	6	1870487-1870583	5	CRISPRCasFinder	no		WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	Orphan	CCACACACGACCCAAATTACGCA	23	0	0	NA	NA	NA	1	1	Orphan	WYL,cas3,DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	NA|84aa|up_4|CP028460.1_1853696_1853948_-,NA|474aa|down_2|CP028460.1_1873151_1874573_+,NA|69aa|down_4|CP028460.1_1876069_1876276_-,NA|319aa|down_6|CP028460.1_1879107_1880064_+	NA|444aa|up_9|CP028460.1_1847342_1848674_-	pfam13416, SBP_bac_8, Bacterial extracellular solute-binding protein	NA|592aa|up_8|CP028460.1_1849031_1850807_+	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins	NA|208aa|up_7|CP028460.1_1851143_1851767_-	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1)	NA|139aa|up_6|CP028460.1_1851974_1852391_+	pfam14019, DUF4235, Protein of unknown function (DUF4235)	NA|259aa|up_5|CP028460.1_1852490_1853267_+	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA	NA|84aa|up_4|CP028460.1_1853696_1853948_-	NA	NA|526aa|up_3|CP028460.1_1853993_1855571_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|636aa|up_2|CP028460.1_1861791_1863699_+	PRK02628, nadE, NAD synthetase; Reviewed	NA|75aa|up_1|CP028460.1_1863881_1864106_-	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ	NA|90aa|up_0|CP028460.1_1864108_1864378_-	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family	NA|253aa|down_0|CP028460.1_1870724_1871483_+	cd01410, SIRT7, SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation	NA|403aa|down_1|CP028460.1_1871640_1872849_-	PRK08198, PRK08198, threonine dehydratase; Provisional	NA|474aa|down_2|CP028460.1_1873151_1874573_+	NA	NA|481aa|down_3|CP028460.1_1874583_1876026_+	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily	NA|69aa|down_4|CP028460.1_1876069_1876276_-	NA	NA|612aa|down_5|CP028460.1_1876471_1878307_-	cd11333, AmyAc_SI_OligoGlu_DGase, Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins	NA|319aa|down_6|CP028460.1_1879107_1880064_+	NA	NA|631aa|down_7|CP028460.1_1880408_1882301_-	pfam05691, Raffinose_syn, Raffinose synthase or seed imbibition protein Sip1	NA|302aa|down_8|CP028460.1_1883219_1884125_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|331aa|down_9|CP028460.1_1884130_1885123_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]
