assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	2	480140-480220	2	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	AACGGCCGAACCGAAGCCGACGCAGC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|229aa|up_6|CP033073.1_470852_471539_+,NA|404aa|up_1|CP033073.1_478350_479562_+,NA|70aa|down_4|CP033073.1_489481_489691_+,NA|162aa|down_5|CP033073.1_489794_490280_-,NA|498aa|down_6|CP033073.1_490584_492078_-	NA|156aa|up_9|CP033073.1_468016_468484_-	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only]	NA|263aa|up_8|CP033073.1_468460_469249_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|443aa|up_7|CP033073.1_469255_470584_-	pfam03583, LIP, Secretory lipase	NA|229aa|up_6|CP033073.1_470852_471539_+	NA	NA|213aa|up_5|CP033073.1_471563_472202_-	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase	NA|690aa|up_4|CP033073.1_472354_474424_-	pfam09362, DUF1996, Domain of unknown function (DUF1996)	NA|334aa|up_3|CP033073.1_475351_476353_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|455aa|up_2|CP033073.1_476543_477908_+	PLN02852, PLN02852, ferredoxin-NADP+ reductase	NA|404aa|up_1|CP033073.1_478350_479562_+	NA	NA|97aa|up_0|CP033073.1_479721_480012_+	pfam06803, DUF1232, Protein of unknown function (DUF1232)	NA|361aa|down_0|CP033073.1_480305_481388_-	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|857aa|down_1|CP033073.1_481878_484449_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|875aa|down_2|CP033073.1_484680_487305_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|612aa|down_3|CP033073.1_487397_489233_-	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|70aa|down_4|CP033073.1_489481_489691_+	NA	NA|162aa|down_5|CP033073.1_489794_490280_-	NA	NA|498aa|down_6|CP033073.1_490584_492078_-	NA	NA|128aa|down_7|CP033073.1_492249_492633_+	pfam03965, Penicillinase_R, Penicillinase repressor	NA|786aa|down_8|CP033073.1_492760_495118_-	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]	NA|246aa|down_9|CP033073.1_495114_495852_-	TIGR02009, Hypothetical_protein_Rv3400/MT3508/Mb3433
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	3	964090-964187	3	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	CGGGGCCGGGGCGGCACGGGTGGTCC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|127aa|up_8|CP033073.1_952732_953113_-,NA|287aa|up_1|CP033073.1_960876_961737_-,NA|333aa|down_3|CP033073.1_968643_969642_+,NA|144aa|down_8|CP033073.1_976009_976441_-	NA|573aa|up_9|CP033073.1_950982_952701_-	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain	NA|127aa|up_8|CP033073.1_952732_953113_-	NA	NA|267aa|up_7|CP033073.1_953352_954153_-	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]	NA|200aa|up_6|CP033073.1_954571_955171_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|250aa|up_5|CP033073.1_955314_956064_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|690aa|up_4|CP033073.1_957165_959235_-	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|333aa|up_3|CP033073.1_959269_960268_-	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]	NA|180aa|up_2|CP033073.1_960264_960804_-	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional	NA|287aa|up_1|CP033073.1_960876_961737_-	NA	NA|626aa|up_0|CP033073.1_961850_963728_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|411aa|down_0|CP033073.1_964339_965572_-	TIGR01372, sarcosine_oxidase_alpha_subunit, sarcosine oxidase, alpha subunit family, heterotetrameric form	NA|472aa|down_1|CP033073.1_965568_966984_-	COG0579, COG0579, Predicted dehydrogenase [General function prediction only]	NA|477aa|down_2|CP033073.1_966980_968411_-	cd07786, FGGY_EcGK_like, Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases	NA|333aa|down_3|CP033073.1_968643_969642_+	NA	NA|513aa|down_4|CP033073.1_969795_971334_+	TIGR00907, Choline_transport_protein, amino acid permease (GABA permease)	NA|364aa|down_5|CP033073.1_971522_972614_+	pfam00924, MS_channel, Mechanosensitive ion channel	NA|460aa|down_6|CP033073.1_972657_974037_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|637aa|down_7|CP033073.1_974077_975988_-	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|144aa|down_8|CP033073.1_976009_976441_-	NA	NA|157aa|down_9|CP033073.1_976474_976945_-	pfam09851, SHOCT, Short C-terminal domain
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	4	1827531-1827803	1,4,1	PILER-CR,CRISPRCasFinder,CRT	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GTGGTCCCCGCGCACGCGGGGGTGGTCCC,GTGGTCCCCGCGCACGCGGGGGTGGTCCC,GTGGTCCCCGCGCACGCGGGGGTGGTCCC	29,29,29	0	0	NA	NA	NA:NA:NA	3,3,4	4	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|697aa|up_8|CP033073.1_1815845_1817936_-,NA|79aa|up_5|CP033073.1_1821252_1821489_+,NA|87aa|up_0|CP033073.1_1826959_1827220_-,NA|182aa|down_1|CP033073.1_1829002_1829548_-,NA|325aa|down_9|CP033073.1_1840336_1841311_-	NA|531aa|up_9|CP033073.1_1814265_1815858_+	COG1887, TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]	NA|697aa|up_8|CP033073.1_1815845_1817936_-	NA	NA|299aa|up_7|CP033073.1_1818767_1819664_-	COG3586, COG3586, Uncharacterized conserved protein [Function unknown]	NA|254aa|up_6|CP033073.1_1820420_1821182_+	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease	NA|79aa|up_5|CP033073.1_1821252_1821489_+	NA	NA|182aa|up_4|CP033073.1_1821682_1822228_-	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like	NA|198aa|up_3|CP033073.1_1822352_1822946_-	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like	NA|394aa|up_2|CP033073.1_1823500_1824682_+	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism]	NA|352aa|up_1|CP033073.1_1825889_1826945_+	cd14103, STKc_MLCK, Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase	NA|87aa|up_0|CP033073.1_1826959_1827220_-	NA	NA|245aa|down_0|CP033073.1_1828228_1828963_+	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071)	NA|182aa|down_1|CP033073.1_1829002_1829548_-	NA	NA|181aa|down_2|CP033073.1_1829757_1830300_-	pfam07098, DUF1360, Protein of unknown function (DUF1360)	NA|405aa|down_3|CP033073.1_1831381_1832596_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|509aa|down_4|CP033073.1_1833383_1834910_+	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]	NA|250aa|down_5|CP033073.1_1834866_1835616_+	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only]	NA|335aa|down_6|CP033073.1_1836798_1837803_+	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]	NA|311aa|down_7|CP033073.1_1837807_1838740_-	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases	NA|184aa|down_8|CP033073.1_1838973_1839525_-	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family	NA|325aa|down_9|CP033073.1_1840336_1841311_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	5	2152877-2152963	5	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GGTGCCCACCCTGTTGTCGTGAC	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|186aa|up_9|CP033073.1_2140147_2140705_+,NA|71aa|up_1|CP033073.1_2148767_2148980_-,NA|144aa|down_4|CP033073.1_2156916_2157348_-,NA|171aa|down_5|CP033073.1_2157804_2158317_+,NA|776aa|down_6|CP033073.1_2158391_2160719_+,NA|200aa|down_7|CP033073.1_2160747_2161347_+,NA|189aa|down_8|CP033073.1_2161387_2161954_+,NA|137aa|down_9|CP033073.1_2162168_2162579_+	NA|186aa|up_9|CP033073.1_2140147_2140705_+	NA	NA|151aa|up_8|CP033073.1_2140873_2141326_-	sd00006, TPR, Tetratricopeptide repeat	NA|251aa|up_7|CP033073.1_2141336_2142089_-	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional	NA|460aa|up_6|CP033073.1_2142135_2143515_-	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|740aa|up_5|CP033073.1_2143511_2145731_-	TIGR02696, polyribonucleotide_nucleotidyltransferase, guanosine pentaphosphate synthetase I/polynucleotide phosphorylase	NA|96aa|up_4|CP033073.1_2146077_2146365_-	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed	NA|98aa|up_3|CP033073.1_2146640_2146934_+	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|503aa|up_2|CP033073.1_2147069_2148578_-	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD	NA|71aa|up_1|CP033073.1_2148767_2148980_-	NA	NA|1322aa|up_0|CP033073.1_2148878_2152844_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|101aa|down_0|CP033073.1_2153020_2153323_-	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|114aa|down_1|CP033073.1_2153361_2153703_-	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|420aa|down_2|CP033073.1_2153815_2155075_-	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin	NA|597aa|down_3|CP033073.1_2155126_2156917_-	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|144aa|down_4|CP033073.1_2156916_2157348_-	NA	NA|171aa|down_5|CP033073.1_2157804_2158317_+	NA	NA|776aa|down_6|CP033073.1_2158391_2160719_+	NA	NA|200aa|down_7|CP033073.1_2160747_2161347_+	NA	NA|189aa|down_8|CP033073.1_2161387_2161954_+	NA	NA|137aa|down_9|CP033073.1_2162168_2162579_+	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	6	2906383-2906470	6	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	ATCCAGCACCGATCCAGCACGGT	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|151aa|up_9|CP033073.1_2899822_2900275_+,NA|128aa|up_7|CP033073.1_2901241_2901625_+,NA|82aa|up_5|CP033073.1_2902246_2902492_+,NA|139aa|down_1|CP033073.1_2907978_2908395_+	NA|151aa|up_9|CP033073.1_2899822_2900275_+	NA	NA|282aa|up_8|CP033073.1_2900303_2901149_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|128aa|up_7|CP033073.1_2901241_2901625_+	NA	NA|181aa|up_6|CP033073.1_2901621_2902164_+	cd03674, Nudix_Hydrolase_1, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|82aa|up_5|CP033073.1_2902246_2902492_+	NA	NA|267aa|up_4|CP033073.1_2902547_2903348_+	PRK00450, dapF, diaminopimelate epimerase; Provisional	NA|364aa|up_3|CP033073.1_2903344_2904436_+	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed	NA|175aa|up_2|CP033073.1_2904472_2904997_+	cd02549, Peptidase_C39A, A sub-family of peptidase family C39	NA|121aa|up_1|CP033073.1_2904996_2905359_+	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]	NA|272aa|up_0|CP033073.1_2905451_2906267_-	pfam01925, TauE, Sulfite exporter TauE/SafE	NA|363aa|down_0|CP033073.1_2906556_2907645_-	PRK09601, PRK09601, redox-regulated ATPase YchF	NA|139aa|down_1|CP033073.1_2907978_2908395_+	NA	NA|249aa|down_2|CP033073.1_2908437_2909184_-	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|339aa|down_3|CP033073.1_2909213_2910230_-	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed	NA|403aa|down_4|CP033073.1_2910432_2911641_+	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit	NA|90aa|down_5|CP033073.1_2911637_2911907_+	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional	NA|197aa|down_6|CP033073.1_2912205_2912796_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|180aa|down_7|CP033073.1_2912860_2913400_-	pfam14030, DUF4245, Protein of unknown function (DUF4245)	NA|345aa|down_8|CP033073.1_2913519_2914554_+	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed	NA|125aa|down_9|CP033073.1_2915033_2915408_-	pfam02467, Whib, Transcription factor WhiB
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	7	3563908-3564544	7	CRISPRCasFinder	no	csa3,cas3,cas6e,cas5,cas7,cse2gr11,cas8e	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Type I-E	ACCTCCGCGGGTGCGGAGCAGAC	23	0	0	NA	NA	NA	10	10	TypeI-E	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|282aa|up_7|CP033073.1_3554438_3555284_+,NA|201aa|up_6|CP033073.1_3555289_3555892_+,NA|88aa|down_1|CP033073.1_3569324_3569588_+,NA|465aa|down_9|CP033073.1_3577687_3579082_-	NA|438aa|up_9|CP033073.1_3552829_3554143_+	cd06839, PLPDE_III_Btrk_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase	NA|89aa|up_8|CP033073.1_3554161_3554428_+	PRK07639, PRK07639, petrobactin biosynthesis protein AsbD	NA|282aa|up_7|CP033073.1_3554438_3555284_+	NA	NA|201aa|up_6|CP033073.1_3555289_3555892_+	NA	NA|387aa|up_5|CP033073.1_3555884_3557045_+	cd00567, ACAD, Acyl-CoA dehydrogenase	NA|138aa|up_4|CP033073.1_3557078_3557492_+	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional	NA|321aa|up_3|CP033073.1_3557722_3558685_+	cd01942, ribokinase_group_A, Ribokinase-like subgroup A	NA|400aa|up_2|CP033073.1_3559051_3560251_-	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II	NA|228aa|up_1|CP033073.1_3560341_3561025_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|491aa|up_0|CP033073.1_3561015_3562488_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	cas3|722aa|down_0|CP033073.1_3567208_3569374_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|88aa|down_1|CP033073.1_3569324_3569588_+	NA	cas6e|221aa|down_2|CP033073.1_3570005_3570668_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|249aa|down_3|CP033073.1_3570664_3571411_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|419aa|down_4|CP033073.1_3571407_3572664_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|181aa|down_5|CP033073.1_3572660_3573203_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|557aa|down_6|CP033073.1_3573147_3574818_-	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	NA|178aa|down_7|CP033073.1_3576231_3576765_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|246aa|down_8|CP033073.1_3576886_3577624_-	COG4627, COG4627, Uncharacterized protein conserved in bacteria [Function unknown]	NA|465aa|down_9|CP033073.1_3577687_3579082_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	8	3564641-3564785	8	CRISPRCasFinder	no	csa3,cas3,cas6e,cas5,cas7,cse2gr11,cas8e	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Type I-E	ACCTCCGCGGGTGCGGAGCAGAC	23	0	0	NA	NA	NA	2	2	TypeI-E	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|282aa|up_7|CP033073.1_3554438_3555284_+,NA|201aa|up_6|CP033073.1_3555289_3555892_+,NA|88aa|down_1|CP033073.1_3569324_3569588_+,NA|465aa|down_9|CP033073.1_3577687_3579082_-	NA|438aa|up_9|CP033073.1_3552829_3554143_+	cd06839, PLPDE_III_Btrk_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase	NA|89aa|up_8|CP033073.1_3554161_3554428_+	PRK07639, PRK07639, petrobactin biosynthesis protein AsbD	NA|282aa|up_7|CP033073.1_3554438_3555284_+	NA	NA|201aa|up_6|CP033073.1_3555289_3555892_+	NA	NA|387aa|up_5|CP033073.1_3555884_3557045_+	cd00567, ACAD, Acyl-CoA dehydrogenase	NA|138aa|up_4|CP033073.1_3557078_3557492_+	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional	NA|321aa|up_3|CP033073.1_3557722_3558685_+	cd01942, ribokinase_group_A, Ribokinase-like subgroup A	NA|400aa|up_2|CP033073.1_3559051_3560251_-	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II	NA|228aa|up_1|CP033073.1_3560341_3561025_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|491aa|up_0|CP033073.1_3561015_3562488_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	cas3|722aa|down_0|CP033073.1_3567208_3569374_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|88aa|down_1|CP033073.1_3569324_3569588_+	NA	cas6e|221aa|down_2|CP033073.1_3570005_3570668_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|249aa|down_3|CP033073.1_3570664_3571411_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|419aa|down_4|CP033073.1_3571407_3572664_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|181aa|down_5|CP033073.1_3572660_3573203_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|557aa|down_6|CP033073.1_3573147_3574818_-	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	NA|178aa|down_7|CP033073.1_3576231_3576765_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|246aa|down_8|CP033073.1_3576886_3577624_-	COG4627, COG4627, Uncharacterized protein conserved in bacteria [Function unknown]	NA|465aa|down_9|CP033073.1_3577687_3579082_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	9	3575213-3575785	2,9,2	PILER-CR,CRISPRCasFinder,CRT	no	cas3,cas6e,cas5,cas7,cse2gr11,cas8e	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Type I-E	GTTCGCTCCGCACCCGCGGAGGTCACCCG,GTTCGCTCCGCACCCGCGGAGGTCACCCGT,CGCTCCGCACCCGCGGAGGTC	29,30,21	0	0	NA	NA	NA:NA:NA	7,8,9	9	TypeI-E	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|88aa|up_5|CP033073.1_3569324_3569588_+,NA|465aa|down_2|CP033073.1_3577687_3579082_-,NA|100aa|down_5|CP033073.1_3580633_3580933_-,NA|163aa|down_9|CP033073.1_3583103_3583592_-	NA|400aa|up_9|CP033073.1_3559051_3560251_-	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II	NA|228aa|up_8|CP033073.1_3560341_3561025_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|491aa|up_7|CP033073.1_3561015_3562488_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	cas3|722aa|up_6|CP033073.1_3567208_3569374_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|88aa|up_5|CP033073.1_3569324_3569588_+	NA	cas6e|221aa|up_4|CP033073.1_3570005_3570668_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|249aa|up_3|CP033073.1_3570664_3571411_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|419aa|up_2|CP033073.1_3571407_3572664_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|181aa|up_1|CP033073.1_3572660_3573203_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|557aa|up_0|CP033073.1_3573147_3574818_-	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	NA|178aa|down_0|CP033073.1_3576231_3576765_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|246aa|down_1|CP033073.1_3576886_3577624_-	COG4627, COG4627, Uncharacterized protein conserved in bacteria [Function unknown]	NA|465aa|down_2|CP033073.1_3577687_3579082_-	NA	NA|255aa|down_3|CP033073.1_3579084_3579849_-	PRK07152, nadD, nicotinate-nucleotide adenylyltransferase	NA|195aa|down_4|CP033073.1_3579888_3580473_-	cd07890, CYTH-like_AC_IV-like, Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily	NA|100aa|down_5|CP033073.1_3580633_3580933_-	NA	NA|170aa|down_6|CP033073.1_3581013_3581523_-	cd04413, NDPk_I, Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside triphosphate (NTP) donor onto a nucleoside diphosphate (NDP) acceptor through a phosphohistidine intermediate	NA|220aa|down_7|CP033073.1_3581931_3582591_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|138aa|down_8|CP033073.1_3582587_3583001_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|163aa|down_9|CP033073.1_3583103_3583592_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	10	3575832-3576043	10	CRISPRCasFinder	no	cas3,cas6e,cas5,cas7,cse2gr11,cas8e	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Type I-E	GTTCGCTCCGCACCCGCGGAGGTCACCCGT	30	0	0	NA	NA	NA	3	3	TypeI-E	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|88aa|up_5|CP033073.1_3569324_3569588_+,NA|465aa|down_2|CP033073.1_3577687_3579082_-,NA|100aa|down_5|CP033073.1_3580633_3580933_-,NA|163aa|down_9|CP033073.1_3583103_3583592_-	NA|400aa|up_9|CP033073.1_3559051_3560251_-	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II	NA|228aa|up_8|CP033073.1_3560341_3561025_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|491aa|up_7|CP033073.1_3561015_3562488_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	cas3|722aa|up_6|CP033073.1_3567208_3569374_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	NA|88aa|up_5|CP033073.1_3569324_3569588_+	NA	cas6e|221aa|up_4|CP033073.1_3570005_3570668_-	pfam08798, CRISPR_assoc, CRISPR associated protein	cas5|249aa|up_3|CP033073.1_3570664_3571411_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|419aa|up_2|CP033073.1_3571407_3572664_-	pfam09344, Cas_CT1975, CT1975-like protein	cse2gr11|181aa|up_1|CP033073.1_3572660_3573203_-	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2)	cas8e|557aa|up_0|CP033073.1_3573147_3574818_-	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1	NA|178aa|down_0|CP033073.1_3576231_3576765_-	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|246aa|down_1|CP033073.1_3576886_3577624_-	COG4627, COG4627, Uncharacterized protein conserved in bacteria [Function unknown]	NA|465aa|down_2|CP033073.1_3577687_3579082_-	NA	NA|255aa|down_3|CP033073.1_3579084_3579849_-	PRK07152, nadD, nicotinate-nucleotide adenylyltransferase	NA|195aa|down_4|CP033073.1_3579888_3580473_-	cd07890, CYTH-like_AC_IV-like, Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily	NA|100aa|down_5|CP033073.1_3580633_3580933_-	NA	NA|170aa|down_6|CP033073.1_3581013_3581523_-	cd04413, NDPk_I, Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside triphosphate (NTP) donor onto a nucleoside diphosphate (NDP) acceptor through a phosphohistidine intermediate	NA|220aa|down_7|CP033073.1_3581931_3582591_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|138aa|down_8|CP033073.1_3582587_3583001_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|163aa|down_9|CP033073.1_3583103_3583592_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	11	4900383-4900454	11	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GTCCGGCAAGGCGGCCGGTGCCG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|150aa|up_8|CP033073.1_4889410_4889860_+,NA|101aa|down_9|CP033073.1_4911286_4911589_-	NA|317aa|up_9|CP033073.1_4888378_4889329_+	TIGR01136, Cysteine_synthase, cysteine synthase	NA|150aa|up_8|CP033073.1_4889410_4889860_+	NA	NA|153aa|up_7|CP033073.1_4889950_4890409_-	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system	NA|437aa|up_6|CP033073.1_4892948_4894259_-	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component	NA|78aa|up_5|CP033073.1_4894443_4894677_+	cd00212, PTS_IIB_glc, PTS_IIB, PTS system, glucose/sucrose specific IIB subunit	NA|246aa|up_4|CP033073.1_4894772_4895510_+	PRK00173, rph, ribonuclease PH; Reviewed	NA|136aa|up_3|CP033073.1_4895730_4896138_+	TIGR02338, Prefoldin_subunit_beta, prefoldin, beta subunit, archaeal	NA|265aa|up_2|CP033073.1_4896229_4897024_-	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|328aa|up_1|CP033073.1_4897033_4898017_-	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA	NA|264aa|up_0|CP033073.1_4897997_4898789_-	pfam06182, ABC2_membrane_6, ABC-2 family transporter protein	NA|941aa|down_0|CP033073.1_4900773_4903596_+	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|107aa|down_1|CP033073.1_4903598_4903919_-	PRK11431, PRK11431, quaternary ammonium compound efflux SMR transporter SugE	NA|120aa|down_2|CP033073.1_4904081_4904441_-	smart00883, Cpn10, Chaperonin 10 Kd subunit	NA|110aa|down_3|CP033073.1_4904495_4904825_-	pfam12277, DUF3618, Protein of unknown function (DUF3618)	NA|156aa|down_4|CP033073.1_4904918_4905386_+	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]	NA|201aa|down_5|CP033073.1_4905682_4906285_-	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed	NA|448aa|down_6|CP033073.1_4906311_4907655_-	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|438aa|down_7|CP033073.1_4907851_4909165_+	pfam04286, DUF445, Protein of unknown function (DUF445)	NA|492aa|down_8|CP033073.1_4909325_4910801_+	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|101aa|down_9|CP033073.1_4911286_4911589_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	12	4900614-4900745	12	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GTCCGGCAAGGCGGCCGGTGCCG	23	0	0	NA	NA	NA	2	2	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|150aa|up_8|CP033073.1_4889410_4889860_+,NA|101aa|down_9|CP033073.1_4911286_4911589_-	NA|317aa|up_9|CP033073.1_4888378_4889329_+	TIGR01136, Cysteine_synthase, cysteine synthase	NA|150aa|up_8|CP033073.1_4889410_4889860_+	NA	NA|153aa|up_7|CP033073.1_4889950_4890409_-	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system	NA|437aa|up_6|CP033073.1_4892948_4894259_-	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component	NA|78aa|up_5|CP033073.1_4894443_4894677_+	cd00212, PTS_IIB_glc, PTS_IIB, PTS system, glucose/sucrose specific IIB subunit	NA|246aa|up_4|CP033073.1_4894772_4895510_+	PRK00173, rph, ribonuclease PH; Reviewed	NA|136aa|up_3|CP033073.1_4895730_4896138_+	TIGR02338, Prefoldin_subunit_beta, prefoldin, beta subunit, archaeal	NA|265aa|up_2|CP033073.1_4896229_4897024_-	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|328aa|up_1|CP033073.1_4897033_4898017_-	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA	NA|264aa|up_0|CP033073.1_4897997_4898789_-	pfam06182, ABC2_membrane_6, ABC-2 family transporter protein	NA|941aa|down_0|CP033073.1_4900773_4903596_+	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]	NA|107aa|down_1|CP033073.1_4903598_4903919_-	PRK11431, PRK11431, quaternary ammonium compound efflux SMR transporter SugE	NA|120aa|down_2|CP033073.1_4904081_4904441_-	smart00883, Cpn10, Chaperonin 10 Kd subunit	NA|110aa|down_3|CP033073.1_4904495_4904825_-	pfam12277, DUF3618, Protein of unknown function (DUF3618)	NA|156aa|down_4|CP033073.1_4904918_4905386_+	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]	NA|201aa|down_5|CP033073.1_4905682_4906285_-	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed	NA|448aa|down_6|CP033073.1_4906311_4907655_-	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|438aa|down_7|CP033073.1_4907851_4909165_+	pfam04286, DUF445, Protein of unknown function (DUF445)	NA|492aa|down_8|CP033073.1_4909325_4910801_+	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|101aa|down_9|CP033073.1_4911286_4911589_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	14	6123928-6124008	14	CRISPRCasFinder	no	DEDDh	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Unclear	TGACGGCGTCCCCGGCTCCCGACG	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|87aa|up_7|CP033073.1_6116039_6116300_+,NA|78aa|up_2|CP033073.1_6121027_6121261_-,NA|67aa|down_2|CP033073.1_6127018_6127219_+,NA|79aa|down_9|CP033073.1_6133230_6133467_-	NA|222aa|up_9|CP033073.1_6113348_6114014_+	pfam13360, PQQ_2, PQQ-like domain	NA|533aa|up_8|CP033073.1_6114144_6115743_+	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]	NA|87aa|up_7|CP033073.1_6116039_6116300_+	NA	NA|268aa|up_6|CP033073.1_6116417_6117221_+	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|252aa|up_5|CP033073.1_6117464_6118220_-	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR	NA|597aa|up_4|CP033073.1_6118225_6120016_-	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|266aa|up_3|CP033073.1_6120180_6120978_-	cd06662, SURF1, SURF1 superfamily	NA|78aa|up_2|CP033073.1_6121027_6121261_-	NA	DEDDh|328aa|up_1|CP033073.1_6121388_6122372_-	PRK06063, PRK06063, DEDDh family exonuclease	NA|237aa|up_0|CP033073.1_6123002_6123713_+	cd02432, Nodulin-21_like_1, Nodulin-21 and CCC1-related protein family	NA|459aa|down_0|CP033073.1_6124073_6125450_-	pfam02515, CoA_transf_3, CoA-transferase family III	NA|502aa|down_1|CP033073.1_6125521_6127027_-	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins	NA|67aa|down_2|CP033073.1_6127018_6127219_+	NA	NA|119aa|down_3|CP033073.1_6127375_6127732_+	pfam04341, DUF485, Protein of unknown function, DUF485	NA|552aa|down_4|CP033073.1_6127728_6129384_+	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain	NA|357aa|down_5|CP033073.1_6129475_6130546_+	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|215aa|down_6|CP033073.1_6130587_6131232_-	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only]	NA|271aa|down_7|CP033073.1_6131309_6132122_-	cd01638, CysQ, CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family	NA|311aa|down_8|CP033073.1_6132241_6133174_+	cd08460, PBP2_DntR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold	NA|79aa|down_9|CP033073.1_6133230_6133467_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	15	6725053-6725152	15	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GCATCGGGCTCTGCTGTGCCGGGC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|139aa|up_5|CP033073.1_6718067_6718484_+,NA|76aa|up_4|CP033073.1_6718467_6718695_+,NA	NA|193aa|up_9|CP033073.1_6711447_6712026_-	pfam13358, DDE_3, DDE superfamily endonuclease	NA|159aa|up_8|CP033073.1_6711971_6712448_-	pfam13592, HTH_33, Winged helix-turn helix	NA|1380aa|up_7|CP033073.1_6712586_6716726_+	pfam01551, Peptidase_M23, Peptidase family M23	NA|189aa|up_6|CP033073.1_6716997_6717564_-	cd09128, PLDc_unchar1_2, Putative catalytic domain, repeat 2, of uncharacterized phospholipase D-like proteins	NA|139aa|up_5|CP033073.1_6718067_6718484_+	NA	NA|76aa|up_4|CP033073.1_6718467_6718695_+	NA	NA|282aa|up_3|CP033073.1_6720039_6720885_+	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism]	NA|338aa|up_2|CP033073.1_6720924_6721938_-	pfam09770, PAT1, Topoisomerase II-associated protein PAT1	NA|146aa|up_1|CP033073.1_6722081_6722519_+	pfam14539, DUF4442, Domain of unknown function (DUF4442)	NA|672aa|up_0|CP033073.1_6722941_6724957_+	pfam00652, Ricin_B_lectin, Ricin-type beta-trefoil lectin domain	NA|350aa|down_0|CP033073.1_6725252_6726302_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|215aa|down_1|CP033073.1_6726533_6727178_+	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|176aa|down_2|CP033073.1_6727234_6727762_-	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E	NA|255aa|down_3|CP033073.1_6727871_6728636_+	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins	NA|191aa|down_4|CP033073.1_6728767_6729340_+	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain	NA|186aa|down_5|CP033073.1_6729402_6729960_+	cd04939, PA2301, PA2301 is an uncharacterized Pseudomonas aeruginosa protein with a YbaK-like domain of unknown function	NA|407aa|down_6|CP033073.1_6729985_6731206_-	PRK08243, PRK08243, 4-hydroxybenzoate 3-monooxygenase; Validated	NA|546aa|down_7|CP033073.1_6731273_6732911_-	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|136aa|down_8|CP033073.1_6733126_6733534_-	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only]	NA|247aa|down_9|CP033073.1_6733676_6734417_+	PRK12418, PRK12418, cysteinyl-tRNA synthetase; Provisional
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	16	6968266-6968352	16	CRISPRCasFinder	no	csa3	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Type I-A	CCTACCCGGGCCGGTCCGCCCGCACC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|196aa|up_9|CP033073.1_6950488_6951076_+,NA|83aa|up_4|CP033073.1_6959410_6959659_+,NA|466aa|down_6|CP033073.1_6974408_6975806_+	NA|196aa|up_9|CP033073.1_6950488_6951076_+	NA	NA|718aa|up_8|CP033073.1_6951250_6953404_-	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion]	NA|263aa|up_7|CP033073.1_6956304_6957093_-	pfam03211, Pectate_lyase, Pectate lyase	NA|453aa|up_6|CP033073.1_6957550_6958909_+	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|141aa|up_5|CP033073.1_6958989_6959412_-	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|83aa|up_4|CP033073.1_6959410_6959659_+	NA	NA|1431aa|up_3|CP033073.1_6959667_6963960_+	cd07539, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporters	NA|360aa|up_2|CP033073.1_6964050_6965130_-	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain	csa3|119aa|up_1|CP033073.1_6965259_6965616_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|223aa|up_0|CP033073.1_6967244_6967913_-	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|183aa|down_0|CP033073.1_6969271_6969820_-	pfam17197, DUF5134, Domain of unknown function (DUF5134)	NA|557aa|down_1|CP033073.1_6970007_6971678_+	pfam13515, FUSC_2, Fusaric acid resistance protein-like	NA|203aa|down_2|CP033073.1_6971674_6972283_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|131aa|down_3|CP033073.1_6972279_6972672_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|180aa|down_4|CP033073.1_6972743_6973283_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|228aa|down_5|CP033073.1_6973310_6973994_-	cd08563, GDPD_TtGDE_like, Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins	NA|466aa|down_6|CP033073.1_6974408_6975806_+	NA	NA|252aa|down_7|CP033073.1_6975844_6976600_+	cd05233, SDR_c, classical (c) SDRs	NA|357aa|down_8|CP033073.1_6976596_6977667_+	cd06502, TA_like, Low-specificity threonine aldolase (TA)	NA|242aa|down_9|CP033073.1_6978370_6979096_-	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	17	7214107-7214197	17	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	CACCCCGTCCCAGGCCGAGGGCGAG	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA,NA|70aa|down_1|CP033073.1_7214775_7214985_+	NA|87aa|up_9|CP033073.1_7203791_7204052_-	COG2261, COG2261, Predicted membrane protein [Function unknown]	NA|323aa|up_8|CP033073.1_7204241_7205210_-	PRK07048, PRK07048, threo-3-hydroxy-L-aspartate ammonia-lyase	NA|341aa|up_7|CP033073.1_7205265_7206288_-	cd06812, PLPDE_III_DSD_D-TA_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1	NA|216aa|up_6|CP033073.1_7206298_7206946_-	COG2964, COG2964, Uncharacterized protein conserved in bacteria [Function unknown]	NA|260aa|up_5|CP033073.1_7207126_7207906_+	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|167aa|up_4|CP033073.1_7207972_7208473_-	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E	NA|358aa|up_3|CP033073.1_7208690_7209764_-	COG0061, nadF, NAD kinase [Coenzyme metabolism]	NA|233aa|up_2|CP033073.1_7210065_7210764_+	pfam14016, DUF4232, Protein of unknown function (DUF4232)	NA|588aa|up_1|CP033073.1_7210992_7212756_+	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins	NA|272aa|up_0|CP033073.1_7212813_7213629_-	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins	NA|106aa|down_0|CP033073.1_7214240_7214558_+	pfam11387, DUF2795, Protein of unknown function (DUF2795)	NA|70aa|down_1|CP033073.1_7214775_7214985_+	NA	NA|135aa|down_2|CP033073.1_7215302_7215707_+	pfam07179, SseB, SseB protein N-terminal domain	NA|137aa|down_3|CP033073.1_7215827_7216238_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|117aa|down_4|CP033073.1_7216311_7216662_-	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains	NA|344aa|down_5|CP033073.1_7216893_7217925_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|302aa|down_6|CP033073.1_7217921_7218827_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|329aa|down_7|CP033073.1_7218823_7219810_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|439aa|down_8|CP033073.1_7219806_7221123_-	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold	NA|674aa|down_9|CP033073.1_7221358_7223380_+	pfam02449, Glyco_hydro_42, Beta-galactosidase
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	18	7281010-7281086	18	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	CACGGAGGAACACGCGTGAACGCC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|332aa|up_8|CP033073.1_7266310_7267306_-,NA|110aa|up_6|CP033073.1_7271071_7271401_+,NA|117aa|down_4|CP033073.1_7288285_7288636_-,NA|125aa|down_5|CP033073.1_7288800_7289175_+	NA|143aa|up_9|CP033073.1_7265889_7266318_-	pfam03995, Inhibitor_I36, Peptidase inhibitor family I36	NA|332aa|up_8|CP033073.1_7266310_7267306_-	NA	NA|1023aa|up_7|CP033073.1_7267479_7270548_+	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment	NA|110aa|up_6|CP033073.1_7271071_7271401_+	NA	NA|188aa|up_5|CP033073.1_7271489_7272053_-	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain	NA|336aa|up_4|CP033073.1_7272766_7273774_+	cd05230, UGD_SDR_e, UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs	NA|545aa|up_3|CP033073.1_7273802_7275437_+	COG2192, COG2192, Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]	NA|332aa|up_2|CP033073.1_7275433_7276429_+	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function	NA|223aa|up_1|CP033073.1_7276425_7277094_+	cd07503, HAD_HisB-N, histidinol phosphate phosphatase and related phosphatases	NA|411aa|up_0|CP033073.1_7279058_7280291_+	cd03800, GT4_sucrose_synthase, sucrose-phosphate synthase and similar proteins	NA|374aa|down_0|CP033073.1_7282608_7283730_+	cd03789, GT9_LPS_heptosyltransferase, lipopolysaccharide heptosyltransferase and similar proteins	NA|314aa|down_1|CP033073.1_7283719_7284661_+	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function	NA|168aa|down_2|CP033073.1_7285721_7286225_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|152aa|down_3|CP033073.1_7287750_7288206_+	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase	NA|117aa|down_4|CP033073.1_7288285_7288636_-	NA	NA|125aa|down_5|CP033073.1_7288800_7289175_+	NA	NA|522aa|down_6|CP033073.1_7289255_7290821_+	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|499aa|down_7|CP033073.1_7291034_7292531_+	PRK08316, PRK08316, acyl-CoA synthetase; Validated	NA|439aa|down_8|CP033073.1_7292680_7293997_-	TIGR02155, Phenylacetate-coenzyme_A_ligase, phenylacetate-CoA ligase	NA|289aa|down_9|CP033073.1_7294253_7295120_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	19	7385901-7385988	19	CRISPRCasFinder	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	CCGCGCGGCGACGCGACACGGACCGGCCGA	30	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA,NA|81aa|down_9|CP033073.1_7395949_7396192_-	NA|117aa|up_9|CP033073.1_7375689_7376040_-	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein	NA|484aa|up_8|CP033073.1_7376036_7377488_-	cd16943, HATPase_AtoS-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS	NA|559aa|up_7|CP033073.1_7377484_7379161_-	cd17595, REC_TrxB, phosphoacceptor receiver (REC) domain a fused response regulator with a thioredoxin reductase output domain	NA|289aa|up_6|CP033073.1_7379381_7380248_+	pfam00582, Usp, Universal stress protein family	NA|412aa|up_5|CP033073.1_7380257_7381493_-	pfam13224, DUF4032, Domain of unknown function (DUF4032)	NA|256aa|up_4|CP033073.1_7381503_7382271_-	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain	NA|210aa|up_3|CP033073.1_7382373_7383003_-	COG3145, AlkB, Alkylated DNA repair protein [DNA replication, recombination, and repair]	NA|209aa|up_2|CP033073.1_7383136_7383763_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|558aa|up_1|CP033073.1_7383812_7385486_+	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed	NA|117aa|up_0|CP033073.1_7385489_7385840_-	COG3189, COG3189, Uncharacterized conserved protein [Function unknown]	NA|470aa|down_0|CP033073.1_7386099_7387509_+	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain	NA|245aa|down_1|CP033073.1_7387550_7388285_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|235aa|down_2|CP033073.1_7388305_7389010_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|616aa|down_3|CP033073.1_7389035_7390883_+	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR	NA|84aa|down_4|CP033073.1_7391477_7391729_-	pfam02467, Whib, Transcription factor WhiB	NA|296aa|down_5|CP033073.1_7392217_7393105_-	PRK03635, PRK03635, ArgP/LysG family DNA-binding transcriptional regulator	NA|205aa|down_6|CP033073.1_7393171_7393786_+	COG1279, COG1279, Lysine efflux permease [General function prediction only]	NA|433aa|down_7|CP033073.1_7393871_7395170_+	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|152aa|down_8|CP033073.1_7395220_7395676_-	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor	NA|81aa|down_9|CP033073.1_7395949_7396192_-	NA
GCA_003675325.1_ASM367532v1	CP033073	Streptomyces sp. Z022 chromosome, complete genome	20	8053487-8053820	3,20,3	PILER-CR,CRISPRCasFinder,CRT	no		csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	Orphan	GTCCTCCCCGCCGACGCGGGGGTGCTTCG,CGAAGCACCCCCGCGTCGGCGGGGAGGAC,CGAAGCACCCCCGCGTCGGCGGGGAGGAC	29,29,29	0	0	NA	NA	NA:NA:NA	5,5,5	5	Orphan	csa3,DEDDh,WYL,cas3,cas6e,cas5,cas7,cse2gr11,cas8e,cas4	NA|59aa|up_1|CP033073.1_8050914_8051091_+,NA|114aa|up_0|CP033073.1_8051182_8051524_-,NA|276aa|down_2|CP033073.1_8059419_8060247_-,NA|134aa|down_7|CP033073.1_8063453_8063855_+	NA|622aa|up_9|CP033073.1_8030795_8032661_-	COG5520, COG5520, O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]	NA|324aa|up_8|CP033073.1_8033011_8033983_+	COG4305, COG4305, Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]	NA|788aa|up_7|CP033073.1_8035040_8037404_+	pfam02057, Glyco_hydro_59, Glycosyl hydrolase family 59	NA|532aa|up_6|CP033073.1_8037463_8039059_+	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE	NA|129aa|up_5|CP033073.1_8045181_8045568_+	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily	NA|319aa|up_4|CP033073.1_8047308_8048265_-	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter	NA|172aa|up_3|CP033073.1_8048315_8048831_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|430aa|up_2|CP033073.1_8049222_8050512_-	pfam00872, Transposase_mut, Transposase, Mutator family	NA|59aa|up_1|CP033073.1_8050914_8051091_+	NA	NA|114aa|up_0|CP033073.1_8051182_8051524_-	NA	NA|431aa|down_0|CP033073.1_8053926_8055219_-	pfam00872, Transposase_mut, Transposase, Mutator family	NA|152aa|down_1|CP033073.1_8056992_8057448_-	COG1961, PinR, Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]	NA|276aa|down_2|CP033073.1_8059419_8060247_-	NA	NA|182aa|down_3|CP033073.1_8060989_8061535_-	pfam06114, Peptidase_M78, IrrE N-terminal-like domain	NA|127aa|down_4|CP033073.1_8061557_8061938_-	pfam01381, HTH_3, Helix-turn-helix	NA|86aa|down_5|CP033073.1_8062055_8062313_+	pfam14452, Multi_ubiq, Multiubiquitin	NA|390aa|down_6|CP033073.1_8062287_8063457_+	PRK06153, PRK06153, hypothetical protein; Provisional	NA|134aa|down_7|CP033073.1_8063453_8063855_+	NA	NA|218aa|down_8|CP033073.1_8064859_8065513_-	cd20287, cupin_pirin-like_N, pirin-like, N-terminal cupin domain	NA|161aa|down_9|CP033073.1_8065787_8066270_-	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair]
