assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	1	288535-288644	1	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TGACGAGCCCGCGCGGCACTTGAGCGAAGCCGACATCCGCAT	42	1	7	288577-288602|288577-288602|288577-288602|288577-288602|288577-288602|288577-288602|288577-288602	NC_010511.1_5125122-5125147|NC_010511.1_5207221-5207196|NC_010511.1_4106371-4106396|NC_010511.1_5125054-5125079|NC_010511.1_2582386-2582361|NC_010511.1_56636-56661|NC_010511.1_56704-56729	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|312aa|up_6|NC_010511.1_279252_280188_-,NA	NA|154aa|up_9|NC_010511.1_277805_278267_+	cd01918, HprK_C, HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria	NA|134aa|up_8|NC_010511.1_278356_278758_+	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism]	NA|107aa|up_7|NC_010511.1_278843_279164_+	COG1925, FruB, Phosphotransferase system, HPr-related proteins [Carbohydrate transport and metabolism]	NA|312aa|up_6|NC_010511.1_279252_280188_-	NA	NA|370aa|up_5|NC_010511.1_280314_281424_-	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only]	NA|383aa|up_4|NC_010511.1_281529_282678_-	TIGR03203, pimD_small, pimeloyl-CoA dehydrogenase, small subunit	NA|401aa|up_3|NC_010511.1_282818_284021_-	TIGR03204, pimC_large, pimeloyl-CoA dehydrogenase, large subunit	NA|692aa|up_2|NC_010511.1_284087_286163_-	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ	NA|401aa|up_1|NC_010511.1_286261_287464_-	PRK07108, PRK07108, acetyl-CoA C-acyltransferase	NA|256aa|up_0|NC_010511.1_287692_288460_+	PRK07231, FabG-like, SDR family oxidoreductase	NA|573aa|down_0|NC_010511.1_288684_290403_+	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|181aa|down_1|NC_010511.1_290488_291031_-	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed	NA|593aa|down_2|NC_010511.1_291049_292828_-	PRK09107, PRK09107, acetolactate synthase 3 catalytic subunit; Validated	NA|164aa|down_3|NC_010511.1_293179_293671_+	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]	NA|486aa|down_4|NC_010511.1_293658_295116_+	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]	NA|246aa|down_5|NC_010511.1_295112_295850_+	pfam01584, CheW, CheW-like domain	NA|562aa|down_6|NC_010511.1_295873_297559_+	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]	NA|748aa|down_7|NC_010511.1_297666_299910_+	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]	NA|356aa|down_8|NC_010511.1_300019_301087_+	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB	NA|574aa|down_9|NC_010511.1_301083_302805_+	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	2	352304-352392	2	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TGGGCTTCGCTCAGGCGCCGCGCGGGC	27	1	1	352331-352365	NC_010511.1_3379149-3379183	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|59aa|up_4|NC_010511.1_348904_349081_-,NA	NA|132aa|up_9|NC_010511.1_343390_343786_-	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs)	NA|169aa|up_8|NC_010511.1_344175_344682_+	TIGR02802, Peptidoglycan-associated_lipoprotein, peptidoglycan-associated lipoprotein	NA|314aa|up_7|NC_010511.1_344789_345731_+	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF	NA|345aa|up_6|NC_010511.1_345727_346762_+	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]	NA|641aa|up_5|NC_010511.1_346885_348808_+	COG0465, HflB, ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]	NA|59aa|up_4|NC_010511.1_348904_349081_-	NA	NA|240aa|up_3|NC_010511.1_349541_350261_+	PRK05177, minC, septum formation inhibitor MinC	NA|272aa|up_2|NC_010511.1_350381_351197_+	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]	NA|90aa|up_1|NC_010511.1_351193_351463_+	PRK00296, minE, cell division topological specificity factor MinE; Reviewed	NA|197aa|up_0|NC_010511.1_351522_352113_+	COG5178, PRP8, U5 snRNP spliceosome subunit [RNA processing and modification]	NA|417aa|down_0|NC_010511.1_352424_353675_-	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism]	NA|777aa|down_1|NC_010511.1_353854_356185_+	COG4249, COG4249, Uncharacterized protein containing caspase domain [General function prediction only]	NA|364aa|down_2|NC_010511.1_356327_357419_+	PRK09354, recA, recombinase A; Provisional	NA|198aa|down_3|NC_010511.1_357816_358410_+	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional	NA|317aa|down_4|NC_010511.1_358406_359357_+	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]	NA|740aa|down_5|NC_010511.1_359360_361580_+	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|1248aa|down_6|NC_010511.1_362108_365852_-	PRK07562, PRK07562, vitamin B12-dependent ribonucleotide reductase	NA|137aa|down_7|NC_010511.1_366474_366885_+	PRK08183, PRK08183, NADH:ubiquinone oxidoreductase subunit NDUFA12	NA|211aa|down_8|NC_010511.1_366946_367579_+	COG4765, COG4765, Uncharacterized protein conserved in bacteria [Function unknown]	NA|350aa|down_9|NC_010511.1_367639_368689_-	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	3	494437-494544	3	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CGGCTTCCGCCGGGGCGCTCGGCTCT	26	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|75aa|up_2|NC_010511.1_493090_493315_-,NA|142aa|up_0|NC_010511.1_493964_494390_+,NA	NA|275aa|up_9|NC_010511.1_479852_480677_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|488aa|up_8|NC_010511.1_480795_482259_-	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|1766aa|up_7|NC_010511.1_482430_487728_+	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|299aa|up_6|NC_010511.1_487749_488646_-	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold	NA|329aa|up_5|NC_010511.1_488741_489728_+	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|711aa|up_4|NC_010511.1_489802_491935_+	COG4953, PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane]	NA|312aa|up_3|NC_010511.1_492071_493007_-	PRK00072, hemC, porphobilinogen deaminase; Reviewed	NA|75aa|up_2|NC_010511.1_493090_493315_-	NA	NA|100aa|up_1|NC_010511.1_493358_493658_-	pfam03992, ABM, Antibiotic biosynthesis monooxygenase	NA|142aa|up_0|NC_010511.1_493964_494390_+	NA	NA|156aa|down_0|NC_010511.1_494604_495072_-	PRK10743, PRK10743, heat shock chaperone IbpA	NA|334aa|down_1|NC_010511.1_495303_496305_+	COG2267, PldB, Lysophospholipase [Lipid metabolism]	NA|263aa|down_2|NC_010511.1_496465_497254_-	cd01641, Bacterial_IMPase_like_1, Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases	NA|680aa|down_3|NC_010511.1_497351_499391_-	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|431aa|down_4|NC_010511.1_499559_500852_-	PRK05321, PRK05321, nicotinate phosphoribosyltransferase; Provisional	NA|170aa|down_5|NC_010511.1_501004_501514_-	pfam16242, Pyrid_ox_like, Pyridoxamine 5'-phosphate oxidase like	NA|70aa|down_6|NC_010511.1_501687_501897_+	COG3585, MopI, Molybdopterin-binding protein [Coenzyme metabolism]	NA|347aa|down_7|NC_010511.1_501902_502943_+	cd01147, HemV-2, Metal binding protein HemV-2	NA|351aa|down_8|NC_010511.1_502939_503992_+	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism]	NA|229aa|down_9|NC_010511.1_504815_505502_-	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	4	568001-568091	4	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	AAGCCCGCGCGGCGCGTGAGCGA	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|94aa|up_4|NC_010511.1_562521_562803_-,NA|116aa|down_3|NC_010511.1_572501_572849_+	NA|303aa|up_9|NC_010511.1_556689_557598_-	COG3637, COG3637, Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]	NA|442aa|up_8|NC_010511.1_557929_559255_-	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism]	NA|304aa|up_7|NC_010511.1_559591_560503_-	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta	NA|276aa|up_6|NC_010511.1_560613_561441_-	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional	NA|334aa|up_5|NC_010511.1_561513_562515_-	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]	NA|94aa|up_4|NC_010511.1_562521_562803_-	NA	NA|285aa|up_3|NC_010511.1_562952_563807_-	COG0583, LysR, Transcriptional regulator [Transcription]	NA|211aa|up_2|NC_010511.1_563923_564556_+	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases	NA|224aa|up_1|NC_010511.1_564777_565449_+	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold	NA|832aa|up_0|NC_010511.1_565466_567962_+	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase	NA|115aa|down_0|NC_010511.1_568315_568660_+	pfam10056, DUF2293, Uncharacterized conserved protein (DUF2293)	NA|731aa|down_1|NC_010511.1_568739_570932_+	PRK05580, PRK05580, primosome assembly protein PriA; Validated	NA|67aa|down_2|NC_010511.1_571932_572133_-	COG2835, COG2835, Uncharacterized conserved protein [Function unknown]	NA|116aa|down_3|NC_010511.1_572501_572849_+	NA	NA|1158aa|down_4|NC_010511.1_573039_576513_-	TIGR02784, ATP-dependent_nuclease_subunit_A, double-strand break repair helicase AddA, alphaproteobacterial type	NA|187aa|down_5|NC_010511.1_576733_577294_+	COG3038, CybB, Cytochrome B561 [Energy production and conversion]	NA|1041aa|down_6|NC_010511.1_577358_580481_-	TIGR02786, conserved_hypothetical_protein, double-strand break repair protein AddB, alphaproteobacterial type	NA|246aa|down_7|NC_010511.1_580477_581215_-	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family	NA|515aa|down_8|NC_010511.1_581251_582796_-	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]	NA|388aa|down_9|NC_010511.1_583262_584426_-	COG1820, NagA, N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	5	640831-640928	5	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TTCTGCTACAATCGGCGAACCGG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|82aa|up_7|NC_010511.1_631607_631853_-,NA|87aa|up_4|NC_010511.1_635880_636141_-,NA|93aa|down_1|NC_010511.1_645260_645539_-	NA|211aa|up_9|NC_010511.1_630034_630667_-	COG1802, GntR, Transcriptional regulators [Transcription]	NA|265aa|up_8|NC_010511.1_630805_631600_+	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|82aa|up_7|NC_010511.1_631607_631853_-	NA	NA|423aa|up_6|NC_010511.1_632029_633298_+	cd07302, CHD, cyclase homology domain	NA|643aa|up_5|NC_010511.1_633625_635554_-	COG5616, COG5616, Predicted integral membrane protein [Function unknown]	NA|87aa|up_4|NC_010511.1_635880_636141_-	NA	NA|285aa|up_3|NC_010511.1_636278_637133_-	TIGR03753, hypothetical_protein, beta-carotene 15,15'-monooxygenase, Brp/Blh family	NA|253aa|up_2|NC_010511.1_637213_637972_-	cd15240, 7tm_ASR-like, Anabaena sensory rhodopsin and similar proteins, member of the seven-transmembrane GPCR superfamily	NA|273aa|up_1|NC_010511.1_638436_639255_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|284aa|up_0|NC_010511.1_639371_640223_+	pfam06724, DUF1206, Domain of Unknown Function (DUF1206)	NA|1057aa|down_0|NC_010511.1_641717_644888_+	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein	NA|93aa|down_1|NC_010511.1_645260_645539_-	NA	NA|171aa|down_2|NC_010511.1_646714_647227_+	pfam03928, Haem_degrading, Haem-degrading	NA|694aa|down_3|NC_010511.1_647369_649451_-	PRK12688, PRK12688, flagellin; Reviewed	NA|148aa|down_4|NC_010511.1_649682_650126_+	pfam07378, FlbT, Flagellar protein FlbT	NA|235aa|down_5|NC_010511.1_650272_650977_-	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter	NA|261aa|down_6|NC_010511.1_650969_651752_-	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system	NA|338aa|down_7|NC_010511.1_651739_652753_-	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins	NA|285aa|down_8|NC_010511.1_652763_653618_-	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins	NA|414aa|down_9|NC_010511.1_653670_654912_-	cd06330, PBP1_As_SBP-like, periplasmic substrate-binding domain of active transport proteins
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	6	725565-725658	6	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CCGGCGCCTCCGGCTACACGCCCGGCCACGA	31	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA	NA|296aa|up_9|NC_010511.1_715823_716711_+	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]	NA|329aa|up_8|NC_010511.1_716700_717687_-	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|199aa|up_7|NC_010511.1_717803_718400_+	cd07390, MPP_AQ1575, Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain	NA|86aa|up_6|NC_010511.1_718454_718712_+	pfam01381, HTH_3, Helix-turn-helix	NA|581aa|up_5|NC_010511.1_718744_720487_+	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]	NA|299aa|up_4|NC_010511.1_720458_721355_-	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs	NA|158aa|up_3|NC_010511.1_721462_721936_+	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|562aa|up_2|NC_010511.1_722244_723930_+	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]	NA|137aa|up_1|NC_010511.1_724064_724475_-	pfam09391, DUF2000, Protein of unknown function (DUF2000)	NA|297aa|up_0|NC_010511.1_724473_725364_+	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]	NA|251aa|down_0|NC_010511.1_725708_726461_-	PRK12547, PRK12547, RNA polymerase sigma factor; Provisional	NA|129aa|down_1|NC_010511.1_726817_727204_+	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed	NA|222aa|down_2|NC_010511.1_727242_727908_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|216aa|down_3|NC_010511.1_728133_728781_-	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|167aa|down_4|NC_010511.1_728842_729343_-	pfam01894, UPF0047, Uncharacterized protein family UPF0047	NA|569aa|down_5|NC_010511.1_729339_731046_-	TIGR04120, DNA_ligase, DNA ligase, ATP-dependent, PP_1105 family	NA|366aa|down_6|NC_010511.1_731042_732140_-	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated	NA|331aa|down_7|NC_010511.1_732299_733292_+	COG4976, COG4976, Predicted methyltransferase (contains TPR repeat) [General function prediction only]	NA|241aa|down_8|NC_010511.1_733395_734118_+	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway)	NA|188aa|down_9|NC_010511.1_734253_734817_+	PRK00083, frr, ribosome recycling factor; Reviewed
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	7	837084-837193	7	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	ATGTCGGCTTCGCTCAGGCGCCGCGC	26	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|101aa|up_6|NC_010511.1_831666_831969_-,NA|66aa|up_2|NC_010511.1_835558_835756_+,NA|58aa|up_0|NC_010511.1_836549_836723_-,NA|71aa|down_1|NC_010511.1_837781_837994_-,NA|272aa|down_2|NC_010511.1_838751_839567_-,NA|90aa|down_4|NC_010511.1_842281_842551_-,NA|54aa|down_6|NC_010511.1_846480_846642_-,NA|154aa|down_8|NC_010511.1_848157_848619_-	NA|58aa|up_9|NC_010511.1_830596_830770_-	pfam05532, CsbD, CsbD-like	NA|90aa|up_8|NC_010511.1_830906_831176_+	pfam05818, TraT, Enterobacterial TraT complement resistance protein	NA|85aa|up_7|NC_010511.1_831261_831516_-	pfam07508, Recombinase, Recombinase	NA|101aa|up_6|NC_010511.1_831666_831969_-	NA	NA|176aa|up_5|NC_010511.1_832295_832823_+	pfam04773, FecR, FecR protein	NA|614aa|up_4|NC_010511.1_832819_834661_+	smart01080, CHASE2, CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria	NA|229aa|up_3|NC_010511.1_834719_835406_-	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|66aa|up_2|NC_010511.1_835558_835756_+	NA	NA|169aa|up_1|NC_010511.1_835772_836279_-	pfam05443, ROS_MUCR, ROS/MUCR transcriptional regulator protein	NA|58aa|up_0|NC_010511.1_836549_836723_-	NA	NA|59aa|down_0|NC_010511.1_837478_837655_-	cd14905, MYSc_Myo44, class XLIV myosin, motor domain	NA|71aa|down_1|NC_010511.1_837781_837994_-	NA	NA|272aa|down_2|NC_010511.1_838751_839567_-	NA	NA|455aa|down_3|NC_010511.1_839921_841286_-	TIGR00895, transport_protein, benzoate transport	NA|90aa|down_4|NC_010511.1_842281_842551_-	NA	NA|489aa|down_5|NC_010511.1_842547_844014_-	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins	NA|54aa|down_6|NC_010511.1_846480_846642_-	NA	NA|456aa|down_7|NC_010511.1_846793_848161_-	cd08152, y4iL_like, Catalase-like heme-binding proteins similar to the uncharacterized y4iL	NA|154aa|down_8|NC_010511.1_848157_848619_-	NA	NA|193aa|down_9|NC_010511.1_849144_849723_-	cd07909, YciF, YciF bacterial stress response protein, ferritin-like iron-binding domain
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	8	1156778-1156887	8	CRISPRCasFinder	no	DEDDh	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Unclear	ATGGCGAAGCAATCCGTCGGATGTCG	26	1	1	1156804-1156861	NC_010511.1_56728-56785	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|92aa|up_4|NC_010511.1_1152435_1152711_-,NA|148aa|down_2|NC_010511.1_1158981_1159425_-,NA|62aa|down_8|NC_010511.1_1165328_1165514_+	NA|296aa|up_9|NC_010511.1_1148229_1149117_+	cd01311, PDC_hydrolase, 2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM)	DEDDh|239aa|up_8|NC_010511.1_1149319_1150036_-	PRK05711, PRK05711, DNA polymerase III subunit epsilon; Provisional	NA|205aa|up_7|NC_010511.1_1150152_1150767_-	PRK00081, coaE, dephospho-CoA kinase; Reviewed	NA|288aa|up_6|NC_010511.1_1150763_1151627_-	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed	NA|211aa|up_5|NC_010511.1_1151672_1152305_-	PRK02478, PRK02478, Maf-like protein; Reviewed	NA|92aa|up_4|NC_010511.1_1152435_1152711_-	NA	NA|277aa|up_3|NC_010511.1_1152872_1153703_-	PRK05339, PRK05339, pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator	NA|358aa|up_2|NC_010511.1_1154218_1155292_+	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated	NA|142aa|up_1|NC_010511.1_1155406_1155832_+	pfam03653, UPF0093, Uncharacterized protein family (UPF0093)	NA|286aa|up_0|NC_010511.1_1155845_1156703_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|371aa|down_0|NC_010511.1_1157165_1158278_+	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	NA|235aa|down_1|NC_010511.1_1158274_1158979_+	pfam09859, Oxygenase-NA, Oxygenase, catalyzing oxidative methylation of damaged DNA	NA|148aa|down_2|NC_010511.1_1158981_1159425_-	NA	NA|116aa|down_3|NC_010511.1_1159604_1159952_+	PRK10019, PRK10019, nickel/cobalt efflux transporter RcnA	NA|811aa|down_4|NC_010511.1_1159958_1162391_+	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family	NA|296aa|down_5|NC_010511.1_1162458_1163346_+	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain	NA|345aa|down_6|NC_010511.1_1163519_1164554_+	cd06325, PBP1_ABC_unchar_transporter, type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions	NA|91aa|down_7|NC_010511.1_1164787_1165060_+	pfam10073, DUF2312, Uncharacterized protein conserved in bacteria (DUF2312)	NA|62aa|down_8|NC_010511.1_1165328_1165514_+	NA	NA|285aa|down_9|NC_010511.1_1165849_1166704_+	COG3971, COG3971, 2-keto-4-pentenoate hydratase [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	9	1555920-1556022	9	CRISPRCasFinder	no	DEDDh	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Unclear	CGGATTTCGGCTTCGCTCAAGCGCCGCGCGGGCTT	35	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|155aa|up_0|NC_010511.1_1555311_1555776_-,NA|89aa|down_5|NC_010511.1_1562064_1562331_-,NA|445aa|down_8|NC_010511.1_1564659_1565994_-,NA|372aa|down_9|NC_010511.1_1566055_1567171_-	NA|872aa|up_9|NC_010511.1_1542903_1545519_+	PRK00390, leuS, leucyl-tRNA synthetase; Validated	NA|179aa|up_8|NC_010511.1_1545683_1546220_+	COG5468, COG5468, Predicted secreted (periplasmic) protein [Function unknown]	NA|343aa|up_7|NC_010511.1_1546216_1547245_+	PRK06585, holA, DNA polymerase III subunit delta; Reviewed	NA|298aa|up_6|NC_010511.1_1547338_1548232_-	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein	NA|282aa|up_5|NC_010511.1_1548266_1549112_-	pfam13614, AAA_31, AAA domain	NA|213aa|up_4|NC_010511.1_1549108_1549747_-	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA|628aa|up_3|NC_010511.1_1549746_1551630_-	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA|438aa|up_2|NC_010511.1_1551804_1553118_-	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA|625aa|up_1|NC_010511.1_1553318_1555193_+	PRK05454, PRK05454, glucans biosynthesis glucosyltransferase MdoH	NA|155aa|up_0|NC_010511.1_1555311_1555776_-	NA	NA|387aa|down_0|NC_010511.1_1556089_1557250_-	COG0626, MetC, Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]	NA|171aa|down_1|NC_010511.1_1557331_1557844_+	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family	NA|306aa|down_2|NC_010511.1_1558000_1558918_+	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family	NA|758aa|down_3|NC_010511.1_1559035_1561309_-	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|149aa|down_4|NC_010511.1_1561320_1561767_-	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]	NA|89aa|down_5|NC_010511.1_1562064_1562331_-	NA	NA|275aa|down_6|NC_010511.1_1562397_1563222_-	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins	NA|404aa|down_7|NC_010511.1_1563302_1564514_-	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs)	NA|445aa|down_8|NC_010511.1_1564659_1565994_-	NA	NA|372aa|down_9|NC_010511.1_1566055_1567171_-	NA
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	10	1942063-1942206	10	CRISPRCasFinder	no	cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Type I-U, Type I-U?,Type I-C	CATGGCCGCCACCAATGAGGCGGAGAGGAATGAGCGGCAGGACGGCGA	48	0	0	NA	NA	NA	1	1	TypeI-U,TypeI-U?,TypeI-C	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|68aa|up_5|NC_010511.1_1934363_1934567_-,NA	NA|291aa|up_9|NC_010511.1_1929251_1930124_-	COG0265, DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]	NA|472aa|up_8|NC_010511.1_1930228_1931644_-	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|422aa|up_7|NC_010511.1_1931717_1932983_-	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins	NA|423aa|up_6|NC_010511.1_1933081_1934350_+	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|68aa|up_5|NC_010511.1_1934363_1934567_-	NA	cas3HD|486aa|up_4|NC_010511.1_1934812_1936270_+	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3	NA|402aa|up_3|NC_010511.1_1936205_1937411_+	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]	cas3|383aa|up_2|NC_010511.1_1937434_1938583_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas5|227aa|up_1|NC_010511.1_1939090_1939771_+	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas8c|601aa|up_0|NC_010511.1_1939767_1941570_+	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1)	cas1|187aa|down_0|NC_010511.1_1942723_1943284_+	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG	cas2|97aa|down_1|NC_010511.1_1943315_1943606_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|297aa|down_2|NC_010511.1_1944271_1945162_-	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional	NA|336aa|down_3|NC_010511.1_1945440_1946448_+	COG1638, DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]	NA|263aa|down_4|NC_010511.1_1946506_1947295_+	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|427aa|down_5|NC_010511.1_1947291_1948572_+	cd08207, RLP_NonPhot, Ribulose bisphosphate carboxylase like proteins from nonphototrophic bacteria	NA|453aa|down_6|NC_010511.1_1948568_1949927_+	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown]	NA|276aa|down_7|NC_010511.1_1950037_1950865_+	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated	NA|340aa|down_8|NC_010511.1_1950861_1951881_+	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent  Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold	NA|285aa|down_9|NC_010511.1_1952047_1952902_+	PRK03592, PRK03592, haloalkane dehalogenase; Provisional
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	11	1943788-1944211	1,11,1	PILER-CR,CRISPRCasFinder,CRT	no	cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Type I-U, Type I-U?,Type I-C	ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC,ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC,ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	31,31,31	0	0	NA	NA	NA:NA:NA	5,6,6	6	TypeI-U,TypeI-U?,TypeI-C	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|68aa|up_8|NC_010511.1_1934363_1934567_-,NA	NA|423aa|up_9|NC_010511.1_1933081_1934350_+	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|68aa|up_8|NC_010511.1_1934363_1934567_-	NA	cas3HD|486aa|up_7|NC_010511.1_1934812_1936270_+	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3	NA|402aa|up_6|NC_010511.1_1936205_1937411_+	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]	cas3|383aa|up_5|NC_010511.1_1937434_1938583_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas5|227aa|up_4|NC_010511.1_1939090_1939771_+	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas8c|601aa|up_3|NC_010511.1_1939767_1941570_+	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1)	cas7b|360aa|up_2|NC_010511.1_1941562_1942642_+	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7	cas1|187aa|up_1|NC_010511.1_1942723_1943284_+	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG	cas2|97aa|up_0|NC_010511.1_1943315_1943606_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|297aa|down_0|NC_010511.1_1944271_1945162_-	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional	NA|336aa|down_1|NC_010511.1_1945440_1946448_+	COG1638, DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]	NA|263aa|down_2|NC_010511.1_1946506_1947295_+	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|427aa|down_3|NC_010511.1_1947291_1948572_+	cd08207, RLP_NonPhot, Ribulose bisphosphate carboxylase like proteins from nonphototrophic bacteria	NA|453aa|down_4|NC_010511.1_1948568_1949927_+	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown]	NA|276aa|down_5|NC_010511.1_1950037_1950865_+	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated	NA|340aa|down_6|NC_010511.1_1950861_1951881_+	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent  Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold	NA|285aa|down_7|NC_010511.1_1952047_1952902_+	PRK03592, PRK03592, haloalkane dehalogenase; Provisional	NA|292aa|down_8|NC_010511.1_1952905_1953781_-	pfam05853, BKACE, beta-keto acid cleavage enzyme	NA|242aa|down_9|NC_010511.1_1953892_1954618_+	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	12	2469416-2469503	12	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	ATCCCTTCGGGATGGCGGATGTGGG	25	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|227aa|down_2|NC_010511.1_2472513_2473194_-,NA|85aa|down_5|NC_010511.1_2477427_2477682_+	NA|763aa|up_9|NC_010511.1_2456049_2458338_-	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]	NA|550aa|up_8|NC_010511.1_2458823_2460473_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|289aa|up_7|NC_010511.1_2460469_2461336_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|314aa|up_6|NC_010511.1_2461332_2462274_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|531aa|up_5|NC_010511.1_2462284_2463877_-	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|576aa|up_4|NC_010511.1_2464212_2465940_-	PRK13207, ureC, urease subunit alpha; Reviewed	NA|378aa|up_3|NC_010511.1_2466065_2467199_+	TIGR02308, T4_RNA_ligase_1, RNA ligase, T4 RnlA family	NA|207aa|up_2|NC_010511.1_2467222_2467843_-	PRK13192, PRK13192, bifunctional urease subunit gamma/beta; Reviewed	NA|283aa|up_1|NC_010511.1_2467919_2468768_-	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]	NA|146aa|up_0|NC_010511.1_2468923_2469361_+	COG4101, COG4101, Predicted mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]	NA|434aa|down_0|NC_010511.1_2469558_2470860_-	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|455aa|down_1|NC_010511.1_2470918_2472283_-	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|227aa|down_2|NC_010511.1_2472513_2473194_-	NA	NA|166aa|down_3|NC_010511.1_2473340_2473838_-	PRK14796, PRK14796, lipoprotein signal peptidase; Provisional	NA|990aa|down_4|NC_010511.1_2474140_2477110_-	PRK13804, ileS, isoleucyl-tRNA synthetase; Provisional	NA|85aa|down_5|NC_010511.1_2477427_2477682_+	NA	NA|322aa|down_6|NC_010511.1_2477668_2478634_-	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase	NA|128aa|down_7|NC_010511.1_2479122_2479506_+	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins	NA|187aa|down_8|NC_010511.1_2479670_2480231_+	pfam04344, CheZ, Chemotaxis phosphatase, CheZ	NA|302aa|down_9|NC_010511.1_2480231_2481137_-	cd07525, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	13	2474014-2474099	13	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GGGCTTCGCTCAAGCGCCGCGCGG	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|227aa|up_1|NC_010511.1_2472513_2473194_-,NA|85aa|down_1|NC_010511.1_2477427_2477682_+	NA|531aa|up_9|NC_010511.1_2462284_2463877_-	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|576aa|up_8|NC_010511.1_2464212_2465940_-	PRK13207, ureC, urease subunit alpha; Reviewed	NA|378aa|up_7|NC_010511.1_2466065_2467199_+	TIGR02308, T4_RNA_ligase_1, RNA ligase, T4 RnlA family	NA|207aa|up_6|NC_010511.1_2467222_2467843_-	PRK13192, PRK13192, bifunctional urease subunit gamma/beta; Reviewed	NA|283aa|up_5|NC_010511.1_2467919_2468768_-	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]	NA|146aa|up_4|NC_010511.1_2468923_2469361_+	COG4101, COG4101, Predicted mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]	NA|434aa|up_3|NC_010511.1_2469558_2470860_-	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|455aa|up_2|NC_010511.1_2470918_2472283_-	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only]	NA|227aa|up_1|NC_010511.1_2472513_2473194_-	NA	NA|166aa|up_0|NC_010511.1_2473340_2473838_-	PRK14796, PRK14796, lipoprotein signal peptidase; Provisional	NA|990aa|down_0|NC_010511.1_2474140_2477110_-	PRK13804, ileS, isoleucyl-tRNA synthetase; Provisional	NA|85aa|down_1|NC_010511.1_2477427_2477682_+	NA	NA|322aa|down_2|NC_010511.1_2477668_2478634_-	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase	NA|128aa|down_3|NC_010511.1_2479122_2479506_+	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins	NA|187aa|down_4|NC_010511.1_2479670_2480231_+	pfam04344, CheZ, Chemotaxis phosphatase, CheZ	NA|302aa|down_5|NC_010511.1_2480231_2481137_-	cd07525, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily	NA|565aa|down_6|NC_010511.1_2481221_2482916_-	COG1001, AdeC, Adenine deaminase [Nucleotide transport and metabolism]	NA|276aa|down_7|NC_010511.1_2483025_2483853_-	PRK06505, PRK06505, enoyl-[acyl-carrier-protein] reductase FabI	NA|409aa|down_8|NC_010511.1_2483888_2485115_-	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I	NA|184aa|down_9|NC_010511.1_2485212_2485764_-	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	14	2625133-2625688	2,14,2	PILER-CR,CRISPRCasFinder,CRT	no	cas2	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Unclear	ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC,ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC,ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	31,31,31	0	0	NA	NA	NA:NA:NA	7,8,8	8	Unclear	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|184aa|down_6|NC_010511.1_2632889_2633441_+	NA|318aa|up_9|NC_010511.1_2612764_2613718_-	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|543aa|up_8|NC_010511.1_2613840_2615469_-	cd01663, Cyt_c_Oxidase_I, Cytochrome C oxidase subunit I	NA|288aa|up_7|NC_010511.1_2615556_2616420_-	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]	NA|303aa|up_6|NC_010511.1_2616801_2617710_+	COG0583, LysR, Transcriptional regulator [Transcription]	NA|133aa|up_5|NC_010511.1_2617740_2618139_-	COG3791, COG3791, Uncharacterized conserved protein [Function unknown]	NA|158aa|up_4|NC_010511.1_2618298_2618772_+	PRK05988, PRK05988, formate dehydrogenase subunit gamma; Validated	NA|520aa|up_3|NC_010511.1_2618768_2620328_+	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]	NA|284aa|up_2|NC_010511.1_2623348_2624200_+	PRK00724, PRK00724, formate dehydrogenase accessory sulfurtransferase FdhD	NA|81aa|up_1|NC_010511.1_2624196_2624439_+	pfam11390, FdsD, NADH-dependant formate dehydrogenase delta subunit FdsD	cas2|95aa|up_0|NC_010511.1_2624666_2624951_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|179aa|down_0|NC_010511.1_2625947_2626484_-	COG3038, CybB, Cytochrome B561 [Energy production and conversion]	NA|256aa|down_1|NC_010511.1_2626495_2627263_-	COG1985, RibD, Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]	NA|371aa|down_2|NC_010511.1_2627314_2628427_+	PRK08815, PRK08815, GTP cyclohydrolase II RibA	NA|255aa|down_3|NC_010511.1_2628476_2629241_-	pfam08241, Methyltransf_11, Methyltransferase domain	NA|258aa|down_4|NC_010511.1_2629319_2630093_+	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain	NA|696aa|down_5|NC_010511.1_2630432_2632520_+	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]	NA|184aa|down_6|NC_010511.1_2632889_2633441_+	NA	NA|329aa|down_7|NC_010511.1_2633561_2634548_+	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases	NA|154aa|down_8|NC_010511.1_2634617_2635079_+	PRK06342, PRK06342, transcription elongation factor GreA	NA|300aa|down_9|NC_010511.1_2635062_2635962_-	COG0583, LysR, Transcriptional regulator [Transcription]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	15	2811010-2811104	15	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	AGGCGCGTTGAGGCTGAACAGCG	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|85aa|up_9|NC_010511.1_2797111_2797366_+,NA|100aa|up_7|NC_010511.1_2800533_2800833_-,NA|125aa|up_6|NC_010511.1_2801362_2801737_-,NA|209aa|down_1|NC_010511.1_2813155_2813782_-,NA|119aa|down_2|NC_010511.1_2813963_2814320_+,NA|89aa|down_8|NC_010511.1_2821720_2821987_+	NA|85aa|up_9|NC_010511.1_2797111_2797366_+	NA	NA|144aa|up_8|NC_010511.1_2797832_2798264_-	pfam00582, Usp, Universal stress protein family	NA|100aa|up_7|NC_010511.1_2800533_2800833_-	NA	NA|125aa|up_6|NC_010511.1_2801362_2801737_-	NA	NA|328aa|up_5|NC_010511.1_2802114_2803098_-	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family	NA|275aa|up_4|NC_010511.1_2803321_2804146_-	cd05971, MACS_like_3, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS)	NA|403aa|up_3|NC_010511.1_2804308_2805517_+	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs)	NA|409aa|up_2|NC_010511.1_2805513_2806740_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|454aa|up_1|NC_010511.1_2806979_2808341_+	PRK05341, PRK05341, homogentisate 1,2-dioxygenase; Provisional	NA|437aa|up_0|NC_010511.1_2808340_2809651_+	TIGR01266, fum_ac_acetase, fumarylacetoacetase	NA|299aa|down_0|NC_010511.1_2812140_2813037_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|209aa|down_1|NC_010511.1_2813155_2813782_-	NA	NA|119aa|down_2|NC_010511.1_2813963_2814320_+	NA	NA|373aa|down_3|NC_010511.1_2815340_2816459_-	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism]	NA|230aa|down_4|NC_010511.1_2816455_2817145_-	PRK09421, modB, molybdate ABC transporter permease subunit	NA|504aa|down_5|NC_010511.1_2817294_2818806_+	PRK08323, PRK08323, phenylhydantoinase; Validated	NA|563aa|down_6|NC_010511.1_2818847_2820536_-	pfam12729, 4HB_MCP_1, Four helix bundle sensory module for signal transduction	NA|151aa|down_7|NC_010511.1_2821042_2821495_+	pfam04940, BLUF, Sensors of blue-light using FAD	NA|89aa|down_8|NC_010511.1_2821720_2821987_+	NA	NA|453aa|down_9|NC_010511.1_2821976_2823335_-	COG4091, COG4091, Predicted homoserine dehydrogenase [Amino acid transport and metabolism]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	16	3015488-3015591	16	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CGCGGCGCTTGAGCGAGGCCGACATCCGCATGGCGA	36	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|68aa|down_9|NC_010511.1_3028753_3028957_-	NA|318aa|up_9|NC_010511.1_3002001_3002955_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|307aa|up_8|NC_010511.1_3002959_3003880_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|348aa|up_7|NC_010511.1_3003876_3004920_+	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional	NA|337aa|up_6|NC_010511.1_3004923_3005934_+	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|107aa|up_5|NC_010511.1_3006165_3006486_+	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE)	NA|363aa|up_4|NC_010511.1_3006482_3007571_+	TIGR03476, HpnL, putative membrane protein	NA|696aa|up_3|NC_010511.1_3007697_3009785_-	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|447aa|up_2|NC_010511.1_3010255_3011596_-	COG3773, SleB, Cell wall hydrolyses involved in spore germination [Cell envelope biogenesis, outer membrane]	NA|892aa|up_1|NC_010511.1_3011855_3014531_-	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional	NA|220aa|up_0|NC_010511.1_3014681_3015341_-	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown]	NA|770aa|down_0|NC_010511.1_3015612_3017922_-	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms]	NA|516aa|down_1|NC_010511.1_3018137_3019685_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|353aa|down_2|NC_010511.1_3019925_3020984_+	pfam15887, Peptidase_Mx, Putative zinc-binding metallo-peptidase	NA|331aa|down_3|NC_010511.1_3021111_3022104_+	pfam18288, FAA_hydro_N_2, Fumarylacetoacetase N-terminal domain 2	NA|148aa|down_4|NC_010511.1_3022180_3022624_+	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins	NA|433aa|down_5|NC_010511.1_3022900_3024199_+	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like	NA|254aa|down_6|NC_010511.1_3024230_3024992_-	PRK06949, PRK06949, SDR family oxidoreductase	NA|149aa|down_7|NC_010511.1_3025012_3025459_-	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|965aa|down_8|NC_010511.1_3025544_3028439_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|68aa|down_9|NC_010511.1_3028753_3028957_-	NA
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	17	3091222-3091326	17	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	AGCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCAT	37	1	5	3091259-3091289|3091259-3091289|3091259-3091289|3091259-3091289|3091259-3091289	NC_010511.1_5207221-5207191|NC_010511.1_5125054-5125084|NC_010511.1_56636-56666|NC_010511.1_56704-56734|NC_010511.1_5125122-5125152	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|97aa|up_8|NC_010511.1_3080780_3081071_+,NA|85aa|up_6|NC_010511.1_3083097_3083352_-,NA|61aa|up_4|NC_010511.1_3084667_3084850_-,NA|71aa|down_0|NC_010511.1_3092751_3092964_+,NA|61aa|down_3|NC_010511.1_3096829_3097012_-	NA|266aa|up_9|NC_010511.1_3079702_3080500_-	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family	NA|97aa|up_8|NC_010511.1_3080780_3081071_+	NA	NA|280aa|up_7|NC_010511.1_3081661_3082501_+	pfam13649, Methyltransf_25, Methyltransferase domain	NA|85aa|up_6|NC_010511.1_3083097_3083352_-	NA	NA|326aa|up_5|NC_010511.1_3083478_3084456_+	pfam12852, Cupin_6, Cupin	NA|61aa|up_4|NC_010511.1_3084667_3084850_-	NA	NA|507aa|up_3|NC_010511.1_3085229_3086750_+	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like	NA|413aa|up_2|NC_010511.1_3087418_3088657_+	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion]	NA|310aa|up_1|NC_010511.1_3088698_3089628_+	pfam01297, ZnuA, Zinc-uptake complex component A periplasmic	NA|467aa|up_0|NC_010511.1_3089624_3091025_+	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]	NA|71aa|down_0|NC_010511.1_3092751_3092964_+	NA	NA|189aa|down_1|NC_010511.1_3094044_3094611_-	COG2863, COG2863, Cytochrome c553 [Energy production and conversion]	NA|350aa|down_2|NC_010511.1_3094667_3095717_-	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]	NA|61aa|down_3|NC_010511.1_3096829_3097012_-	NA	NA|154aa|down_4|NC_010511.1_3097318_3097780_-	pfam07883, Cupin_2, Cupin domain	NA|511aa|down_5|NC_010511.1_3097908_3099441_+	COG5616, COG5616, Predicted integral membrane protein [Function unknown]	NA|279aa|down_6|NC_010511.1_3099795_3100633_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|375aa|down_7|NC_010511.1_3100704_3101829_+	pfam13358, DDE_3, DDE superfamily endonuclease	NA|208aa|down_8|NC_010511.1_3102143_3102767_+	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif	NA|425aa|down_9|NC_010511.1_3102775_3104050_-	cd07302, CHD, cyclase homology domain
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	18	3272004-3272098	18	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TCGGCGTCGCTCAAACGCCGCGCGGGC	27	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|96aa|up_5|NC_010511.1_3264399_3264687_-,NA|86aa|up_0|NC_010511.1_3271694_3271952_+,NA	NA|688aa|up_9|NC_010511.1_3258075_3260139_+	PRK15015, PRK15015, carbon starvation protein CstA	NA|75aa|up_8|NC_010511.1_3260146_3260371_+	pfam04328, Sel_put, Selenoprotein, putative	NA|312aa|up_7|NC_010511.1_3260719_3261655_+	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]	NA|777aa|up_6|NC_010511.1_3261720_3264051_+	COG2183, Tex, Transcriptional accessory protein [Transcription]	NA|96aa|up_5|NC_010511.1_3264399_3264687_-	NA	NA|148aa|up_4|NC_010511.1_3264997_3265441_-	TIGR01985, kDa_protein, phasin	NA|1001aa|up_3|NC_010511.1_3265679_3268682_+	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|439aa|up_2|NC_010511.1_3268778_3270095_+	cd06334, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions	NA|447aa|up_1|NC_010511.1_3270289_3271630_+	PRK10406, PRK10406, alpha-ketoglutarate transporter; Provisional	NA|86aa|up_0|NC_010511.1_3271694_3271952_+	NA	NA|650aa|down_0|NC_010511.1_3272385_3274335_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|103aa|down_1|NC_010511.1_3274657_3274966_+	pfam04341, DUF485, Protein of unknown function, DUF485	NA|564aa|down_2|NC_010511.1_3274962_3276654_+	PRK09395, actP, cation/acetate symporter ActP	NA|507aa|down_3|NC_010511.1_3276793_3278314_-	TIGR03023, Sugar_transferase	NA|469aa|down_4|NC_010511.1_3278415_3279822_-	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|191aa|down_5|NC_010511.1_3279964_3280537_-	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]	NA|760aa|down_6|NC_010511.1_3280712_3282992_+	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]	NA|169aa|down_7|NC_010511.1_3283208_3283715_+	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown]	NA|113aa|down_8|NC_010511.1_3284044_3284383_-	cd02238, cupin_KdgF, pectin degradation protein KdgF and related proteins, cupin domain	NA|125aa|down_9|NC_010511.1_3284435_3284810_-	pfam08000, bPH_1, Bacterial PH domain
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	19	3439717-3439883	19	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TCGCTCAGGCGCCGCGCGGGCTTG	24	1	4	3439741-3439785|3439741-3439785|3439741-3439785|3439741-3439785	NC_010511.1_4201622-4201666|NC_010511.1_6308404-6308360|NC_010511.1_6308473-6308429|NC_010511.1_1978178-1978222	NA	2	2	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|528aa|down_2|NC_010511.1_3446555_3448139_-,NA|317aa|down_4|NC_010511.1_3449226_3450177_+,NA|254aa|down_7|NC_010511.1_3453911_3454673_+	NA|144aa|up_9|NC_010511.1_3430027_3430459_+	cd04776, HTH_GnyR, Helix-Turn-Helix DNA binding domain of the regulatory protein GnyR	NA|430aa|up_8|NC_010511.1_3430814_3432104_+	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment	NA|212aa|up_7|NC_010511.1_3432200_3432836_-	PRK09289, PRK09289, riboflavin synthase	NA|399aa|up_6|NC_010511.1_3432799_3433996_-	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD	NA|187aa|up_5|NC_010511.1_3433992_3434553_-	PRK00464, nrdR, transcriptional repressor NrdR	NA|434aa|up_4|NC_010511.1_3434660_3435962_-	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|70aa|up_3|NC_010511.1_3436296_3436506_-	pfam04102, SlyX, SlyX	NA|427aa|up_2|NC_010511.1_3436602_3437883_-	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NC_010511.1_3438147_3438576_+	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|324aa|up_0|NC_010511.1_3438649_3439621_+	pfam07987, DUF1775, Domain of unkown function (DUF1775)	NA|99aa|down_0|NC_010511.1_3441147_3441444_-	pfam09981, DUF2218, Uncharacterized protein conserved in bacteria (DUF2218)	NA|785aa|down_1|NC_010511.1_3441455_3443810_-	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|528aa|down_2|NC_010511.1_3446555_3448139_-	NA	NA|210aa|down_3|NC_010511.1_3448465_3449095_+	pfam08795, DUF1796, Putative papain-like cysteine peptidase (DUF1796)	NA|317aa|down_4|NC_010511.1_3449226_3450177_+	NA	NA|482aa|down_5|NC_010511.1_3450390_3451836_-	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein	NA|290aa|down_6|NC_010511.1_3452229_3453099_-	pfam18588, WcbI, Polysaccharide biosynthesis enzyme WcbI	NA|254aa|down_7|NC_010511.1_3453911_3454673_+	NA	NA|368aa|down_8|NC_010511.1_3454669_3455773_+	pfam08885, GSCFA, GSCFA family	NA|210aa|down_9|NC_010511.1_3456309_3456939_+	pfam13578, Methyltransf_24, Methyltransferase domain
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	20	3661571-3661665	20	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GGGCTTCGCTCAGGCGCCGCGCGGGCTGGTGAT	33	1	5	3661604-3661632|3661604-3661632|3661604-3661632|3661604-3661632|3661604-3661632	NC_010511.1_6742420-6742392|NC_010511.1_2953403-2953431|NC_010511.1_3252569-3252597|NC_010511.1_3986276-3986304|NC_010511.1_2075342-2075314	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|145aa|up_9|NC_010511.1_3651378_3651813_-,NA|127aa|down_4|NC_010511.1_3668852_3669233_+,NA|77aa|down_9|NC_010511.1_3675687_3675918_+	NA|145aa|up_9|NC_010511.1_3651378_3651813_-	NA	NA|164aa|up_8|NC_010511.1_3651952_3652444_+	cd07909, YciF, YciF bacterial stress response protein, ferritin-like iron-binding domain	NA|138aa|up_7|NC_010511.1_3652514_3652928_+	cd08354, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|333aa|up_6|NC_010511.1_3652921_3653920_-	PRK00292, glk, glucokinase; Provisional	NA|317aa|up_5|NC_010511.1_3653994_3654945_-	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]	NA|249aa|up_4|NC_010511.1_3655179_3655926_+	COG1802, GntR, Transcriptional regulators [Transcription]	NA|292aa|up_3|NC_010511.1_3656085_3656961_-	cd08427, PBP2_LTTR_like_2, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|313aa|up_2|NC_010511.1_3657056_3657995_+	cd00408, DHDPS-like, Dihydrodipicolinate synthase family	NA|160aa|up_1|NC_010511.1_3659220_3659700_+	cd00618, PLA2_like, PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent	NA|548aa|up_0|NC_010511.1_3659706_3661350_-	PRK02106, PRK02106, choline dehydrogenase; Validated	NA|326aa|down_0|NC_010511.1_3661697_3662675_-	pfam00535, Glycos_transf_2, Glycosyl transferase family 2	NA|334aa|down_1|NC_010511.1_3662962_3663964_-	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands	NA|545aa|down_2|NC_010511.1_3663974_3665609_-	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis	NA|588aa|down_3|NC_010511.1_3665931_3667695_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|127aa|down_4|NC_010511.1_3668852_3669233_+	NA	NA|363aa|down_5|NC_010511.1_3669722_3670811_-	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit	NA|375aa|down_6|NC_010511.1_3670826_3671951_-	pfam02350, Epimerase_2, UDP-N-acetylglucosamine 2-epimerase	NA|443aa|down_7|NC_010511.1_3671973_3673302_-	PRK14716, PRK14716, glycosyl transferase family protein	NA|362aa|down_8|NC_010511.1_3674177_3675263_+	pfam00015, MCPsignal, Methyl-accepting chemotaxis protein (MCP) signalling domain	NA|77aa|down_9|NC_010511.1_3675687_3675918_+	NA
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	21	3891727-3891791	21	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GCCGCGGCCTCGGCTTGGGCCTC	23	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|323aa|up_4|NC_010511.1_3878173_3879142_-,NA|405aa|down_4|NC_010511.1_3897378_3898593_+	NA|708aa|up_9|NC_010511.1_3870530_3872654_-	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion]	NA|284aa|up_8|NC_010511.1_3873001_3873853_-	PRK09120, PRK09120, p-hydroxycinnamoyl CoA hydratase/lyase; Validated	NA|482aa|up_7|NC_010511.1_3873879_3875325_-	cd07105, ALDH_SaliADH, Salicylaldehyde dehydrogenase, DoxF-like	NA|148aa|up_6|NC_010511.1_3875408_3875852_+	COG1846, MarR, Transcriptional regulators [Transcription]	NA|388aa|up_5|NC_010511.1_3876980_3878144_+	cd03326, MR_like_1, Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 1	NA|323aa|up_4|NC_010511.1_3878173_3879142_-	NA	NA|543aa|up_3|NC_010511.1_3879304_3880933_+	cd11331, AmyAc_OligoGlu_like, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase) and related proteins	NA|225aa|up_2|NC_010511.1_3886692_3887367_-	COG1802, GntR, Transcriptional regulators [Transcription]	NA|984aa|up_1|NC_010511.1_3887395_3890347_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|398aa|up_0|NC_010511.1_3890458_3891652_+	PLN02409, PLN02409, serine--glyoxylate aminotransaminase	NA|183aa|down_0|NC_010511.1_3894692_3895241_+	COG4675, MdpB, Microcystin-dependent protein [Function unknown]	NA|179aa|down_1|NC_010511.1_3895762_3896299_+	COG4675, MdpB, Microcystin-dependent protein [Function unknown]	NA|165aa|down_2|NC_010511.1_3896303_3896798_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|196aa|down_3|NC_010511.1_3896794_3897382_+	pfam05118, Asp_Arg_Hydrox, Aspartyl/Asparaginyl beta-hydroxylase	NA|405aa|down_4|NC_010511.1_3897378_3898593_+	NA	NA|207aa|down_5|NC_010511.1_3898756_3899377_+	pfam08242, Methyltransf_12, Methyltransferase domain	NA|662aa|down_6|NC_010511.1_3899373_3901359_+	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide	NA|290aa|down_7|NC_010511.1_3901395_3902265_-	PRK05855, PRK05855, SDR family oxidoreductase	NA|514aa|down_8|NC_010511.1_3902486_3904028_-	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases	NA|269aa|down_9|NC_010511.1_3904040_3904847_-	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	22	3951374-3951483	22	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CGAAGCCGAAATCCGCTTGGCGAAGCAATCCGTCGGATTTCG	42	1	20	3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441|3951416-3951441	NC_010511.1_4106327-4106352|NC_010511.1_69440-69415|NC_010511.1_567995-568020|NC_010511.1_1140907-1140882|NC_010511.1_2582430-2582405|NC_010511.1_3820689-3820664|NC_010511.1_4213633-4213608|NC_010511.1_5099469-5099494|NC_010511.1_7489635-7489610|NC_010511.1_1031973-1031948|NC_010511.1_1883793-1883768|NC_010511.1_2279730-2279755|NC_010511.1_2360250-2360275|NC_010511.1_3501858-3501883|NC_010511.1_4201695-4201670|NC_010511.1_4397334-4397359|NC_010511.1_4786628-4786603|NC_010511.1_6468502-6468477|NC_010511.1_6992761-6992736|NC_010511.1_7622403-7622428	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA	NA|177aa|up_9|NC_010511.1_3939678_3940209_-	TIGR00777, AhpD_protein	NA|185aa|up_8|NC_010511.1_3940220_3940775_-	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides	NA|296aa|up_7|NC_010511.1_3941098_3941986_+	TIGR03309, matur_yqeB, selenium-dependent molybdenum hydroxylase system protein, YqeB family	NA|281aa|up_6|NC_010511.1_3942005_3942848_+	cd01573, modD_like, ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport	NA|300aa|up_5|NC_010511.1_3943665_3944565_+	PRK13234, nifH, nitrogenase reductase; Reviewed	NA|506aa|up_4|NC_010511.1_3944719_3946237_+	TIGR01282, Nitrogenase_molybdenum-iron_protein_alpha_chain, nitrogenase molybdenum-iron protein alpha chain	NA|513aa|up_3|NC_010511.1_3946337_3947876_+	TIGR01286, Nitrogenase_molybdenum-iron_protein_beta_chain, nitrogenase molybdenum-iron protein beta chain	NA|504aa|up_2|NC_010511.1_3947947_3949459_+	PRK14478, PRK14478, nitrogenase molybdenum-cofactor biosynthesis protein NifE; Provisional	NA|461aa|up_1|NC_010511.1_3949469_3950852_+	PRK14476, PRK14476, nitrogenase molybdenum-cofactor biosynthesis protein NifN; Provisional	NA|165aa|up_0|NC_010511.1_3950820_3951315_+	TIGR02663, Protein_NifX, nitrogen fixation protein NifX	NA|159aa|down_0|NC_010511.1_3951531_3952008_+	TIGR02935, UPF0460_protein_in_nifX_3'region, probable nitrogen fixation protein	NA|66aa|down_1|NC_010511.1_3952019_3952217_+	pfam05082, Rop-like, Rop-like	NA|105aa|down_2|NC_010511.1_3952269_3952584_+	TIGR02936, fdxN_nitrog, ferredoxin III, nif-specific	NA|218aa|down_3|NC_010511.1_3952587_3953241_+	pfam04891, NifQ, NifQ	NA|95aa|down_4|NC_010511.1_3953387_3953672_+	pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain	NA|266aa|down_5|NC_010511.1_3953753_3954551_+	cd05233, SDR_c, classical (c) SDRs	NA|455aa|down_6|NC_010511.1_3955548_3956913_+	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed	NA|762aa|down_7|NC_010511.1_3956986_3959272_+	PRK12862, PRK12862, malic enzyme; Reviewed	NA|209aa|down_8|NC_010511.1_3959540_3960167_+	PRK06201, PRK06201, hypothetical protein; Validated	NA|434aa|down_9|NC_010511.1_3960236_3961538_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	23	3970270-3970366	23	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TCGCTCAAGCGCCGCGCGGGCTTGTCAT	28	1	2	3970298-3970338|3970298-3970338	NC_010511.1_2067925-2067885|NC_010511.1_4778559-4778599	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|331aa|down_0|NC_010511.1_3970444_3971437_-	NA|266aa|up_9|NC_010511.1_3953753_3954551_+	cd05233, SDR_c, classical (c) SDRs	NA|455aa|up_8|NC_010511.1_3955548_3956913_+	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed	NA|762aa|up_7|NC_010511.1_3956986_3959272_+	PRK12862, PRK12862, malic enzyme; Reviewed	NA|209aa|up_6|NC_010511.1_3959540_3960167_+	PRK06201, PRK06201, hypothetical protein; Validated	NA|434aa|up_5|NC_010511.1_3960236_3961538_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily	NA|416aa|up_4|NC_010511.1_3962913_3964161_-	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|648aa|up_3|NC_010511.1_3964157_3966101_-	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|126aa|up_2|NC_010511.1_3966097_3966475_-	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins	NA|756aa|up_1|NC_010511.1_3966551_3968819_-	TIGR02100, Glycogen_operon_protein_GlgX_homolog, glycogen debranching enzyme GlgX	NA|388aa|up_0|NC_010511.1_3969065_3970229_-	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold	NA|331aa|down_0|NC_010511.1_3970444_3971437_-	NA	NA|985aa|down_1|NC_010511.1_3972124_3975079_-	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional	NA|550aa|down_2|NC_010511.1_3975285_3976935_+	TIGR02361, Dihydroxyacetone_kinase_1, dihydroxyacetone kinase, ATP-dependent	NA|318aa|down_3|NC_010511.1_3977045_3977999_+	cd12164, GDH_like_2, Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family	NA|406aa|down_4|NC_010511.1_3978210_3979428_+	TIGR03453, partition_RepA, plasmid partitioning protein RepA	NA|354aa|down_5|NC_010511.1_3979424_3980486_+	TIGR03454, partition_RepB, plasmid partitioning protein RepB	NA|218aa|down_6|NC_010511.1_3980825_3981479_+	cd09916, CpxP_like, CpxP component of the bacterial Cpx-two-component system and related proteins	NA|231aa|down_7|NC_010511.1_3981495_3982188_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|415aa|down_8|NC_010511.1_3982184_3983429_+	PRK10604, PRK10604, sensor protein RstB; Provisional	NA|270aa|down_9|NC_010511.1_3983462_3984272_-	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	24	4167983-4168117	24	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GCCGACATCCGCATGGCCGAAATCGGAGATGGCGAAGCCATCAACCGGATG	51	1	2	4168034-4168066|4168034-4168066	NC_010511.1_5125007-5125039|NC_010511.1_4094283-4094251	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|101aa|up_9|NC_010511.1_4157847_4158150_+,NA|48aa|up_0|NC_010511.1_4167777_4167921_+,NA	NA|101aa|up_9|NC_010511.1_4157847_4158150_+	NA	NA|354aa|up_8|NC_010511.1_4158146_4159208_+	PRK13654, PRK13654, magnesium-protoporphyrin IX monomethyl ester cyclase; Provisional	NA|269aa|up_7|NC_010511.1_4159212_4160019_+	pfam12291, DUF3623, Protein of unknown function (DUF3623)	NA|404aa|up_6|NC_010511.1_4160066_4161278_+	PRK09064, PRK09064, 5-aminolevulinate synthase; Validated	NA|369aa|up_5|NC_010511.1_4161375_4162482_+	PRK13407, bchI, magnesium chelatase subunit I; Provisional	NA|582aa|up_4|NC_010511.1_4162478_4164224_+	PRK13406, bchD, magnesium chelatase subunit D; Provisional	NA|294aa|up_3|NC_010511.1_4164235_4165117_+	TIGR03056, bchO_mg_che_rel, putative magnesium chelatase accessory protein	NA|509aa|up_2|NC_010511.1_4165209_4166736_+	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase	NA|352aa|up_1|NC_010511.1_4166716_4167772_+	cd00683, Trans_IPPS_HH, Trans-Isoprenyl Diphosphate Synthases, head-to-head	NA|48aa|up_0|NC_010511.1_4167777_4167921_+	NA	NA|428aa|down_0|NC_010511.1_4168319_4169603_+	PRK06837, PRK06837, ArgE/DapE family deacylase	NA|696aa|down_1|NC_010511.1_4169795_4171883_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|614aa|down_2|NC_010511.1_4171900_4173742_-	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|218aa|down_3|NC_010511.1_4173814_4174468_-	PRK06995, flhF, flagellar biosynthesis protein FlhF	NA|207aa|down_4|NC_010511.1_4174742_4175363_+	COG3707, AmiR, Response regulator with putative antiterminator output domain [Signal transduction mechanisms]	NA|335aa|down_5|NC_010511.1_4175359_4176364_+	pfam13379, NMT1_2, NMT1-like family	NA|432aa|down_6|NC_010511.1_4176864_4178160_+	pfam13379, NMT1_2, NMT1-like family	NA|289aa|down_7|NC_010511.1_4178159_4179026_+	TIGR01183, Nitrate_transport_permease_protein_NrtB, nitrate ABC transporter, permease protein	NA|265aa|down_8|NC_010511.1_4179039_4179834_+	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]	NA|406aa|down_9|NC_010511.1_4179844_4181062_+	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	25	4213536-4213631	25	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TCGCTCACGCGCCGCGCGGGCTTGGCA	27	1	12	4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604|4213563-4213604	NC_010511.1_4201625-4201666|NC_010511.1_6308401-6308360|NC_010511.1_217512-217553|NC_010511.1_3902323-3902364|NC_010511.1_4240563-4240522|NC_010511.1_6308470-6308429|NC_010511.1_6763130-6763089|NC_010511.1_1978181-1978222|NC_010511.1_2953395-2953436|NC_010511.1_5807372-5807413|NC_010511.1_3070289-3070248|NC_010511.1_6897353-6897312	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|78aa|up_6|NC_010511.1_4208962_4209196_+,NA|91aa|up_4|NC_010511.1_4210436_4210709_+,NA|104aa|down_0|NC_010511.1_4213666_4213978_-,NA|90aa|down_2|NC_010511.1_4215048_4215318_+,NA|71aa|down_4|NC_010511.1_4215944_4216157_-,NA|83aa|down_6|NC_010511.1_4218553_4218802_+	NA|633aa|up_9|NC_010511.1_4204566_4206465_-	cd06427, CESA_like_2, CESA_like_2 is a member of the cellulose synthase superfamily	NA|296aa|up_8|NC_010511.1_4206582_4207470_+	cd01001, PBP2_HisJ_LAO_like, Substrate binding domain of ABC-type histidine/lysine/arginine/ornithine transporters and related proteins; the type 2 periplasmic-binding protein fold	NA|216aa|up_7|NC_010511.1_4207491_4208139_+	PRK10542, PRK10542, glutathionine S-transferase; Provisional	NA|78aa|up_6|NC_010511.1_4208962_4209196_+	NA	NA|392aa|up_5|NC_010511.1_4209264_4210440_+	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]	NA|91aa|up_4|NC_010511.1_4210436_4210709_+	NA	NA|154aa|up_3|NC_010511.1_4210763_4211225_+	COG3753, COG3753, Uncharacterized protein conserved in bacteria [Function unknown]	NA|124aa|up_2|NC_010511.1_4211258_4211630_-	pfam12680, SnoaL_2, SnoaL-like domain	NA|163aa|up_1|NC_010511.1_4211642_4212131_-	pfam02566, OsmC, OsmC-like protein	NA|349aa|up_0|NC_010511.1_4212228_4213275_+	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair]	NA|104aa|down_0|NC_010511.1_4213666_4213978_-	NA	NA|218aa|down_1|NC_010511.1_4213974_4214628_-	cd00229, SGNH_hydrolase, SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases	NA|90aa|down_2|NC_010511.1_4215048_4215318_+	NA	NA|63aa|down_3|NC_010511.1_4215610_4215799_-	pfam05638, T6SS_HCP, Type VI secretion system effector, Hcp	NA|71aa|down_4|NC_010511.1_4215944_4216157_-	NA	NA|637aa|down_5|NC_010511.1_4216424_4218335_-	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family	NA|83aa|down_6|NC_010511.1_4218553_4218802_+	NA	NA|344aa|down_7|NC_010511.1_4218822_4219854_+	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB	NA|147aa|down_8|NC_010511.1_4219992_4220433_-	pfam02656, DUF202, Domain of unknown function (DUF202)	NA|431aa|down_9|NC_010511.1_4220462_4221755_-	COG4850, COG4850, Uncharacterized conserved protein [Function unknown]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	26	4322263-4322341	26	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	TAGATGTACCGGAAGTGGTACTGGAGA	27	1	1	4322290-4322314	NC_010511.1_6184467-6184491	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|157aa|up_2|NC_010511.1_4320672_4321143_-,NA|133aa|up_0|NC_010511.1_4321417_4321816_-,NA|183aa|down_0|NC_010511.1_4322372_4322921_-,NA|85aa|down_1|NC_010511.1_4322917_4323172_-,NA|191aa|down_3|NC_010511.1_4323429_4324002_-,NA|65aa|down_6|NC_010511.1_4326444_4326639_-,NA|193aa|down_7|NC_010511.1_4326650_4327229_-	NA|262aa|up_9|NC_010511.1_4312138_4312924_-	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]	NA|284aa|up_8|NC_010511.1_4312920_4313772_-	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]	NA|835aa|up_7|NC_010511.1_4313768_4316273_-	COG0404, GcvT, Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]	NA|202aa|up_6|NC_010511.1_4316662_4317268_+	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain	NA|446aa|up_5|NC_010511.1_4317324_4318662_-	PRK09221, PRK09221, beta alanine--pyruvate transaminase; Provisional	NA|184aa|up_4|NC_010511.1_4318807_4319359_+	PRK09943, PRK09943, HTH-type transcriptional regulator PuuR	NA|74aa|up_3|NC_010511.1_4320409_4320631_+	pfam12244, DUF3606, Protein of unknown function (DUF3606)	NA|157aa|up_2|NC_010511.1_4320672_4321143_-	NA	NA|71aa|up_1|NC_010511.1_4321233_4321446_-	cd04765, HTH_MlrA-like_sg2, Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators	NA|133aa|up_0|NC_010511.1_4321417_4321816_-	NA	NA|183aa|down_0|NC_010511.1_4322372_4322921_-	NA	NA|85aa|down_1|NC_010511.1_4322917_4323172_-	NA	NA|83aa|down_2|NC_010511.1_4323168_4323417_-	pfam12728, HTH_17, Helix-turn-helix domain	NA|191aa|down_3|NC_010511.1_4323429_4324002_-	NA	NA|381aa|down_4|NC_010511.1_4324121_4325264_+	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|350aa|down_5|NC_010511.1_4325411_4326461_-	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase	NA|65aa|down_6|NC_010511.1_4326444_4326639_-	NA	NA|193aa|down_7|NC_010511.1_4326650_4327229_-	NA	NA|200aa|down_8|NC_010511.1_4329342_4329942_+	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases	NA|391aa|down_9|NC_010511.1_4330446_4331619_+	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	27	4397341-4397435	27	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	AGCCCGCGCGGCGCTTGAGCGAAGCC	26	1	2	4397367-4397409|4397367-4397409	NC_010511.1_3902360-3902318|NC_010511.1_6763093-6763135	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|130aa|down_8|NC_010511.1_4407708_4408098_+	NA|105aa|up_9|NC_010511.1_4387983_4388298_+	PRK01310, PRK01310, hypothetical protein; Validated	NA|349aa|up_8|NC_010511.1_4388374_4389421_+	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes	NA|164aa|up_7|NC_010511.1_4389433_4389925_-	PRK11050, PRK11050, manganese-binding transcriptional regulator MntR	NA|232aa|up_6|NC_010511.1_4390135_4390831_+	COG4662, TupA, ABC-type tungstate transport system, periplasmic component [Coenzyme metabolism]	NA|244aa|up_5|NC_010511.1_4390827_4391559_+	cd03260, ABC_PstB_phosphate_transporter, ATP-binding cassette domain of the phosphate transport system	NA|272aa|up_4|NC_010511.1_4391528_4392344_+	COG2998, TupA, tungsten ABC transporter substrate-binding protein [Coenzyme metabolism]	NA|548aa|up_3|NC_010511.1_4392417_4394061_+	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs	NA|234aa|up_2|NC_010511.1_4394121_4394823_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|452aa|up_1|NC_010511.1_4395325_4396681_+	PRK08927, fliI, flagellar protein export ATPase FliI	NA|136aa|up_0|NC_010511.1_4396807_4397215_+	TIGR02473, conserved_hypothetical_protein, flagellar export protein FliJ	NA|194aa|down_0|NC_010511.1_4397488_4398070_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|296aa|down_1|NC_010511.1_4398229_4399117_+	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|351aa|down_2|NC_010511.1_4399246_4400299_+	COG0392, COG0392, Predicted integral membrane protein [Function unknown]	NA|284aa|down_3|NC_010511.1_4400305_4401157_+	pfam13578, Methyltransf_24, Methyltransferase domain	NA|315aa|down_4|NC_010511.1_4401397_4402342_-	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]	NA|479aa|down_5|NC_010511.1_4402431_4403868_-	pfam02515, CoA_transf_3, CoA-transferase family III	NA|387aa|down_6|NC_010511.1_4403928_4405089_+	cd06102, citrate_synt_like_2, Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle)	NA|709aa|down_7|NC_010511.1_4405244_4407371_-	PRK06012, flhA, flagellar type III secretion system protein FlhA	NA|130aa|down_8|NC_010511.1_4407708_4408098_+	NA	NA|275aa|down_9|NC_010511.1_4408143_4408968_+	pfam06897, DUF1269, Protein of unknown function (DUF1269)
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	28	4448429-4448515	28	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	AGCCCGCGCGGCGCCTGAGCGAAGCC	26	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|110aa|up_8|NC_010511.1_4433571_4433901_+,NA|522aa|up_2|NC_010511.1_4444155_4445721_+,NA|151aa|down_2|NC_010511.1_4452679_4453132_+,NA|164aa|down_3|NC_010511.1_4453189_4453681_+,NA|168aa|down_4|NC_010511.1_4453730_4454234_+,NA|77aa|down_7|NC_010511.1_4457563_4457794_+,NA|216aa|down_9|NC_010511.1_4458121_4458769_-	NA|64aa|up_9|NC_010511.1_4433375_4433567_-	pfam12728, HTH_17, Helix-turn-helix domain	NA|110aa|up_8|NC_010511.1_4433571_4433901_+	NA	NA|388aa|up_7|NC_010511.1_4434163_4435327_-	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain	NA|586aa|up_6|NC_010511.1_4436673_4438431_+	sd00006, TPR, Tetratricopeptide repeat	NA|517aa|up_5|NC_010511.1_4438560_4440111_-	cd02537, GT8_Glycogenin, Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen	NA|536aa|up_4|NC_010511.1_4440412_4442020_-	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated	NA|520aa|up_3|NC_010511.1_4442557_4444117_+	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|522aa|up_2|NC_010511.1_4444155_4445721_+	NA	NA|392aa|up_1|NC_010511.1_4445717_4446893_+	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|457aa|up_0|NC_010511.1_4446855_4448226_+	COG4238, COG4238, Murein lipoprotein [Cell envelope biogenesis, outer membrane]	NA|200aa|down_0|NC_010511.1_4448727_4449327_-	pfam17784, Sulfotransfer_4, Sulfotransferase domain	NA|326aa|down_1|NC_010511.1_4450311_4451289_+	COG0438, RfaG, Glycosyltransferase [Cell envelope biogenesis, outer membrane]	NA|151aa|down_2|NC_010511.1_4452679_4453132_+	NA	NA|164aa|down_3|NC_010511.1_4453189_4453681_+	NA	NA|168aa|down_4|NC_010511.1_4453730_4454234_+	NA	NA|311aa|down_5|NC_010511.1_4454237_4455170_+	pfam00535, Glycos_transf_2, Glycosyl transferase family 2	NA|667aa|down_6|NC_010511.1_4455166_4457167_+	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase	NA|77aa|down_7|NC_010511.1_4457563_4457794_+	NA	NA|76aa|down_8|NC_010511.1_4457810_4458038_-	pfam13817, DDE_Tnp_IS66_C, IS66 C-terminal element	NA|216aa|down_9|NC_010511.1_4458121_4458769_-	NA
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	29	4808266-4808359	29	CRISPRCasFinder	no	csa3	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Type I-A	GCCTGCGCGGCGCCTGAGCGAAGCC	25	1	6	4808291-4808334|4808291-4808334|4808291-4808334|4808291-4808334|4808291-4808334|4808291-4808334	NC_010511.1_3156598-3156641|NC_010511.1_1811107-1811150|NC_010511.1_3283980-3283937|NC_010511.1_3661571-3661528|NC_010511.1_4477604-4477561|NC_010511.1_6410249-6410292	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|79aa|up_5|NC_010511.1_4803105_4803342_-,NA|119aa|up_0|NC_010511.1_4807869_4808226_+,NA|132aa|down_3|NC_010511.1_4814648_4815044_+,NA|71aa|down_4|NC_010511.1_4815097_4815310_-	NA|135aa|up_9|NC_010511.1_4800002_4800407_+	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147)	NA|412aa|up_8|NC_010511.1_4800738_4801974_+	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|141aa|up_7|NC_010511.1_4801981_4802404_-	pfam14248, DUF4345, Domain of unknown function (DUF4345)	NA|163aa|up_6|NC_010511.1_4802503_4802992_+	PRK10146, PRK10146, aminoalkylphosphonate N-acetyltransferase	NA|79aa|up_5|NC_010511.1_4803105_4803342_-	NA	NA|223aa|up_4|NC_010511.1_4803589_4804258_+	PRK13972, PRK13972, GSH-dependent disulfide bond oxidoreductase; Provisional	NA|166aa|up_3|NC_010511.1_4804301_4804799_-	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147)	NA|141aa|up_2|NC_010511.1_4805072_4805495_+	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated	NA|700aa|up_1|NC_010511.1_4805616_4807716_+	cd02766, MopB_3, The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site	NA|119aa|up_0|NC_010511.1_4807869_4808226_+	NA	csa3|328aa|down_0|NC_010511.1_4808569_4809553_+	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]	NA|307aa|down_1|NC_010511.1_4809638_4810559_+	TIGR00676, 510-methylenetetrahydrofolate_reductase	NA|1248aa|down_2|NC_010511.1_4810761_4814505_+	PRK09490, metH, B12-dependent methionine synthase; Provisional	NA|132aa|down_3|NC_010511.1_4814648_4815044_+	NA	NA|71aa|down_4|NC_010511.1_4815097_4815310_-	NA	NA|182aa|down_5|NC_010511.1_4815479_4816025_+	pfam08714, Fae, Formaldehyde-activating enzyme (Fae)	NA|345aa|down_6|NC_010511.1_4816157_4817192_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|405aa|down_7|NC_010511.1_4817301_4818516_-	TIGR03862, flavo_PP4765, uncharacterized flavoprotein, PP_4765 family	NA|342aa|down_8|NC_010511.1_4818691_4819717_+	TIGR03718, R_switched_Alx, integral membrane protein, TerC family	NA|398aa|down_9|NC_010511.1_4820091_4821285_-	PLN02409, PLN02409, serine--glyoxylate aminotransaminase
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	30	4878890-4879137	30	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GTGCCGTCAGTGTCCGGGTCCGCCGCCTT	29	0	0	NA	NA	NA	3	3	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|78aa|up_0|NC_010511.1_4878538_4878772_+,NA	NA|459aa|up_9|NC_010511.1_4863362_4864739_+	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit	NA|1040aa|up_8|NC_010511.1_4864749_4867869_+	PRK10503, PRK10503, MdtB/MuxB family multidrug efflux RND transporter permease subunit	NA|1094aa|up_7|NC_010511.1_4868014_4871296_+	PRK10614, PRK10614, multidrug efflux system subunit MdtC; Provisional	NA|497aa|up_6|NC_010511.1_4871292_4872783_+	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family	NA|304aa|up_5|NC_010511.1_4872824_4873736_-	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like	NA|250aa|up_4|NC_010511.1_4874365_4875115_-	pfam04471, Mrr_cat, Restriction endonuclease	NA|261aa|up_3|NC_010511.1_4875315_4876098_+	pfam06707, DUF1194, Protein of unknown function (DUF1194)	NA|146aa|up_2|NC_010511.1_4876129_4876567_-	COG4957, COG4957, Predicted transcriptional regulator [Transcription]	NA|382aa|up_1|NC_010511.1_4877235_4878381_-	cd07302, CHD, cyclase homology domain	NA|78aa|up_0|NC_010511.1_4878538_4878772_+	NA	NA|441aa|down_0|NC_010511.1_4879359_4880682_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|202aa|down_1|NC_010511.1_4880782_4881388_-	TIGR03030, Cellulose_synthase_UDP-forming, cellulose synthase catalytic subunit (UDP-forming)	NA|384aa|down_2|NC_010511.1_4881718_4882870_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|385aa|down_3|NC_010511.1_4883100_4884255_+	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|153aa|down_4|NC_010511.1_4884238_4884697_-	pfam03918, CcmH, Cytochrome C biogenesis protein	NA|661aa|down_5|NC_010511.1_4884701_4886684_-	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]	NA|164aa|down_6|NC_010511.1_4886810_4887302_-	PRK13254, PRK13254, cytochrome c maturation protein CcmE	NA|421aa|down_7|NC_010511.1_4887418_4888681_-	COG4235, COG4235, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]	NA|409aa|down_8|NC_010511.1_4888888_4890115_+	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|491aa|down_9|NC_010511.1_4890450_4891923_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	31	4920618-4920708	31	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CGACATCCGGTTGATCGCTTCGC	23	1	1	4920641-4920685	NC_010511.1_5619222-5619266	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|162aa|up_5|NC_010511.1_4914736_4915222_+,NA|98aa|down_0|NC_010511.1_4920813_4921107_-,NA|69aa|down_1|NC_010511.1_4921332_4921539_+,NA|58aa|down_2|NC_010511.1_4921535_4921709_+,NA|86aa|down_9|NC_010511.1_4928542_4928800_-	NA|190aa|up_9|NC_010511.1_4912125_4912695_-	PTZ00146, PTZ00146, fibrillarin; Provisional	NA|247aa|up_8|NC_010511.1_4912821_4913562_+	COG3698, COG3698, Predicted periplasmic protein [Function unknown]	NA|167aa|up_7|NC_010511.1_4913605_4914106_+	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional	NA|180aa|up_6|NC_010511.1_4914207_4914747_+	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]	NA|162aa|up_5|NC_010511.1_4914736_4915222_+	NA	NA|154aa|up_4|NC_010511.1_4915214_4915676_+	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]	NA|223aa|up_3|NC_010511.1_4915801_4916470_-	COG2802, COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]	NA|303aa|up_2|NC_010511.1_4916536_4917445_-	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|586aa|up_1|NC_010511.1_4917685_4919443_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|328aa|up_0|NC_010511.1_4919583_4920567_+	TIGR01136, Cysteine_synthase, cysteine synthase	NA|98aa|down_0|NC_010511.1_4920813_4921107_-	NA	NA|69aa|down_1|NC_010511.1_4921332_4921539_+	NA	NA|58aa|down_2|NC_010511.1_4921535_4921709_+	NA	NA|202aa|down_3|NC_010511.1_4921790_4922396_+	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains	NA|234aa|down_4|NC_010511.1_4922397_4923099_+	cd06217, FNR_iron_sulfur_binding_3, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain	NA|465aa|down_5|NC_010511.1_4923192_4924587_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|261aa|down_6|NC_010511.1_4924643_4925426_-	pfam10670, DUF4198, Domain of unknown function (DUF4198)	NA|399aa|down_7|NC_010511.1_4925870_4927067_+	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|419aa|down_8|NC_010511.1_4927289_4928546_-	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]	NA|86aa|down_9|NC_010511.1_4928542_4928800_-	NA
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	32	4969703-4969780	32	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GCATCATTCGCCGAAGTGGTCACC	24	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|124aa|up_6|NC_010511.1_4961603_4961975_-,NA|100aa|down_4|NC_010511.1_4972455_4972755_+,NA|236aa|down_5|NC_010511.1_4972816_4973524_+,NA|113aa|down_6|NC_010511.1_4973646_4973985_-	NA|68aa|up_9|NC_010511.1_4956626_4956830_-	pfam05532, CsbD, CsbD-like	NA|1054aa|up_8|NC_010511.1_4956930_4960092_-	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family	NA|385aa|up_7|NC_010511.1_4960103_4961258_-	PRK15030, PRK15030, multidrug efflux RND transporter periplasmic adaptor subunit AcrA	NA|124aa|up_6|NC_010511.1_4961603_4961975_-	NA	NA|278aa|up_5|NC_010511.1_4962059_4962893_-	pfam05853, BKACE, beta-keto acid cleavage enzyme	NA|319aa|up_4|NC_010511.1_4962889_4963846_-	PRK07066, PRK07066, L-carnitine dehydrogenase	NA|327aa|up_3|NC_010511.1_4963992_4964973_+	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily	NA|278aa|up_2|NC_010511.1_4965048_4965882_+	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]	NA|268aa|up_1|NC_010511.1_4965887_4966691_+	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters	NA|918aa|up_0|NC_010511.1_4966853_4969607_-	PRK05298, PRK05298, excinuclease ABC subunit UvrB	NA|305aa|down_0|NC_010511.1_4969842_4970757_-	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain	NA|133aa|down_1|NC_010511.1_4970908_4971307_+	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|179aa|down_2|NC_010511.1_4971317_4971854_+	cd07255, VOC_BsCatE_like_N, N-terminal of Bacillus subtilis CatE like protein	NA|91aa|down_3|NC_010511.1_4971807_4972080_-	pfam11730, DUF3297, Protein of unknown function (DUF3297)	NA|100aa|down_4|NC_010511.1_4972455_4972755_+	NA	NA|236aa|down_5|NC_010511.1_4972816_4973524_+	NA	NA|113aa|down_6|NC_010511.1_4973646_4973985_-	NA	NA|292aa|down_7|NC_010511.1_4974152_4975028_-	cd00254, LT-like, lytic transglycosylase(LT)-like domain	NA|540aa|down_8|NC_010511.1_4975168_4976788_+	COG4172, COG4172, ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]	NA|406aa|down_9|NC_010511.1_4976784_4978002_+	PRK05362, PRK05362, phosphopentomutase; Provisional
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	33	5581840-5581960	33	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GCCATCCCCGATTTCGGCAACGCGGATGTCGGCGTCGCTC	40	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|70aa|down_0|NC_010511.1_5582014_5582224_-	NA|300aa|up_9|NC_010511.1_5572122_5573022_+	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]	NA|64aa|up_8|NC_010511.1_5573127_5573319_-	pfam06698, DUF1192, Protein of unknown function (DUF1192)	NA|45aa|up_7|NC_010511.1_5573636_5573771_+	pfam00468, Ribosomal_L34, Ribosomal protein L34	NA|139aa|up_6|NC_010511.1_5573808_5574225_+	pfam00825, Ribonuclease_P, Ribonuclease P	NA|625aa|up_5|NC_010511.1_5574333_5576208_+	PRK01318, PRK01318, membrane protein insertase; Provisional	NA|217aa|up_4|NC_010511.1_5576207_5576858_+	PRK00454, engB, GTP-binding protein YsxC; Reviewed	NA|135aa|up_3|NC_010511.1_5576857_5577262_+	COG2363, COG2363, Uncharacterized small membrane protein [Function unknown]	NA|222aa|up_2|NC_010511.1_5577215_5577881_-	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain	NA|879aa|up_1|NC_010511.1_5578160_5580797_-	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB	NA|258aa|up_0|NC_010511.1_5581035_5581809_+	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only]	NA|70aa|down_0|NC_010511.1_5582014_5582224_-	NA	NA|631aa|down_1|NC_010511.1_5582570_5584463_-	PRK12688, PRK12688, flagellin; Reviewed	NA|432aa|down_2|NC_010511.1_5584953_5586249_-	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|216aa|down_3|NC_010511.1_5586326_5586974_-	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]	NA|441aa|down_4|NC_010511.1_5587170_5588493_-	TIGR02332, putative_4-hydroxyphenylacetate_permease, 4-hydroxyphenylacetate permease	NA|307aa|down_5|NC_010511.1_5588647_5589568_-	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain	NA|398aa|down_6|NC_010511.1_5589564_5590758_-	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]	NA|645aa|down_7|NC_010511.1_5591495_5593430_+	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer)	NA|309aa|down_8|NC_010511.1_5593592_5594519_-	cd08421, PBP2_LTTR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|133aa|down_9|NC_010511.1_5594690_5595089_+	pfam13564, DoxX_2, DoxX-like family
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	34	6319863-6320977	34,3,3	CRISPRCasFinder,CRT,PILER-CR	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC,GTTTCAATCCGCACCCCCGTGAGGGGG,CCCCCTCACGGGGGTGCGGATTGAAAC	33,27,27	0	0	NA	NA	NA:NA:NA	16,16,15	16	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA	NA|245aa|up_9|NC_010511.1_6311080_6311815_+	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]	NA|247aa|up_8|NC_010511.1_6311819_6312560_+	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters	NA|322aa|up_7|NC_010511.1_6312576_6313542_+	TIGR04559, metallo-beta-lactamase_family_protein, quinoprotein relay system zinc metallohydrolase 2	NA|600aa|up_6|NC_010511.1_6313994_6315794_+	cd10278, PQQ_MDH, Large subunit of methanol dehydrogenase (moxF)	NA|204aa|up_5|NC_010511.1_6315932_6316544_+	TIGR03874, 4cys_cytochr, c-type cytochrome, methanol metabolism-related	NA|287aa|up_4|NC_010511.1_6316579_6317440_+	TIGR03871, extracellular_solute-binding_protein_family_3, quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein	NA|178aa|up_3|NC_010511.1_6317436_6317970_+	TIGR03865, PQQ_CXXCW, PQQ-dependent catabolism-associated CXXCW motif protein	NA|159aa|up_2|NC_010511.1_6318048_6318525_-	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism]	NA|127aa|up_1|NC_010511.1_6318537_6318918_-	COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism]	NA|296aa|up_0|NC_010511.1_6318917_6319805_-	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes	NA|270aa|down_0|NC_010511.1_6321319_6322129_+	TIGR04557, hypothetical_protein, quinoprotein dehydrogenase-associated SoxYZ-like carrier	NA|311aa|down_1|NC_010511.1_6322135_6323068_-	pfam04199, Cyclase, Putative cyclase	NA|527aa|down_2|NC_010511.1_6323206_6324787_+	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|235aa|down_3|NC_010511.1_6324830_6325535_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|30aa|down_4|NC_010511.1_6325774_6325864_+	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA	NA|30aa|down_5|NC_010511.1_6325939_6326029_+	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA	NA|300aa|down_6|NC_010511.1_6326077_6326977_+	PRK05184, PRK05184, pyrroloquinoline quinone biosynthesis protein PqqB; Provisional	NA|267aa|down_7|NC_010511.1_6327392_6328193_+	PRK05157, PRK05157, pyrroloquinoline quinone biosynthesis protein PqqC; Provisional	NA|96aa|down_8|NC_010511.1_6328189_6328477_+	TIGR03859, PQQ_PqqD, coenzyme PQQ biosynthesis protein PqqD	NA|380aa|down_9|NC_010511.1_6328567_6329707_+	PRK05301, PRK05301, pyrroloquinoline quinone biosynthesis protein PqqE; Provisional
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	35	6365050-6365147	35	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	CAAGCCCGCGCGGCGCGTGAGCGAAACCGA	30	0	0	NA	NA	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA,NA|74aa|down_1|NC_010511.1_6367924_6368146_-,NA|71aa|down_3|NC_010511.1_6371780_6371993_+,NA|249aa|down_5|NC_010511.1_6372681_6373428_+,NA|93aa|down_6|NC_010511.1_6373409_6373688_-,NA|103aa|down_7|NC_010511.1_6373892_6374201_+,NA|102aa|down_8|NC_010511.1_6374375_6374681_+	NA|385aa|up_9|NC_010511.1_6339893_6341048_+	COG2232, COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase [General function prediction only]	NA|325aa|up_8|NC_010511.1_6341044_6342019_+	PRK02264, PRK02264, N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Provisional	NA|306aa|up_7|NC_010511.1_6342214_6343132_+	TIGR00768, Tetrahydromethanopterin:alpha-L-glutamate_ligase, alpha-L-glutamate ligase, RimK family	NA|287aa|up_6|NC_010511.1_6343131_6343992_+	pfam01874, CitG, ATP:dephospho-CoA triphosphoribosyl transferase	NA|172aa|up_5|NC_010511.1_6344239_6344755_+	TIGR03126, one_C_fae, formaldehyde-activating enzyme	NA|206aa|up_4|NC_010511.1_6345079_6345697_-	pfam06776, IalB, Invasion associated locus B (IalB) protein	NA|4856aa|up_3|NC_010511.1_6345909_6360477_-	TIGR01901, Heme/hemopexin-binding_protein, filamentous hemagglutinin family N-terminal domain	NA|618aa|up_2|NC_010511.1_6360493_6362347_-	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion]	NA|243aa|up_1|NC_010511.1_6363164_6363893_-	cd04723, HisA_HisF, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase (HisA) and the cyclase subunit of imidazoleglycerol phosphate synthase (HisF)	NA|354aa|up_0|NC_010511.1_6363934_6364996_+	TIGR03123, one_C_unchar_1, probable H4MPT-linked C1 transfer pathway protein	NA|842aa|down_0|NC_010511.1_6365175_6367701_-	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase	NA|74aa|down_1|NC_010511.1_6367924_6368146_-	NA	NA|264aa|down_2|NC_010511.1_6370586_6371378_+	COG3703, ChaC, Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]	NA|71aa|down_3|NC_010511.1_6371780_6371993_+	NA	NA|60aa|down_4|NC_010511.1_6372293_6372473_+	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ	NA|249aa|down_5|NC_010511.1_6372681_6373428_+	NA	NA|93aa|down_6|NC_010511.1_6373409_6373688_-	NA	NA|103aa|down_7|NC_010511.1_6373892_6374201_+	NA	NA|102aa|down_8|NC_010511.1_6374375_6374681_+	NA	NA|355aa|down_9|NC_010511.1_6374694_6375759_-	COG4638, HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]
GCF_000019365.1_ASM1936v1	NC_010511	Methylobacterium sp. 4-46, complete sequence	36	6830727-6830833	36	CRISPRCasFinder	no		DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	Orphan	GCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATGGC	39	1	6	6830766-6830794|6830766-6830794|6830766-6830794|6830766-6830794|6830766-6830794|6830766-6830794	NC_010511.1_3148199-3148171|NC_010511.1_4808389-4808417|NC_010511.1_5892075-5892103|NC_010511.1_27850-27822|NC_010511.1_973126-973154|NC_010511.1_3832528-3832500	NA	1	1	Orphan	DEDDh,csa3,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	NA|68aa|up_9|NC_010511.1_6819912_6820116_+,NA|53aa|up_8|NC_010511.1_6820234_6820393_+,NA|83aa|up_3|NC_010511.1_6824725_6824974_-,NA	NA|68aa|up_9|NC_010511.1_6819912_6820116_+	NA	NA|53aa|up_8|NC_010511.1_6820234_6820393_+	NA	NA|299aa|up_7|NC_010511.1_6820490_6821387_+	cd08447, PBP2_LTTR_aromatics_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to regulators involved in the catabolism of aromatic compounds, contains type 2 periplasmic binding fold	NA|452aa|up_6|NC_010511.1_6821524_6822880_+	TIGR03247, glucar-dehydr, glucarate dehydratase	NA|257aa|up_5|NC_010511.1_6822901_6823672_+	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism]	NA|294aa|up_4|NC_010511.1_6823689_6824571_+	PRK15059, PRK15059, 2-hydroxy-3-oxopropionate reductase	NA|83aa|up_3|NC_010511.1_6824725_6824974_-	NA	NA|248aa|up_2|NC_010511.1_6825614_6826358_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|343aa|up_1|NC_010511.1_6826383_6827412_+	cd16433, CheB, Chemotaxis response regulator protein-glutamate methylesterase, CheB	NA|1062aa|up_0|NC_010511.1_6827505_6830691_+	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]	NA|178aa|down_0|NC_010511.1_6831132_6831666_-	pfam00072, Response_reg, Response regulator receiver domain	NA|282aa|down_1|NC_010511.1_6832365_6833211_+	COG0714, COG0714, MoxR-like ATPases [General function prediction only]	NA|175aa|down_2|NC_010511.1_6833224_6833749_+	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms]	NA|452aa|down_3|NC_010511.1_6834017_6835373_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|482aa|down_4|NC_010511.1_6835493_6836939_+	pfam04317, DUF463, YcjX-like family, DUF463	NA|337aa|down_5|NC_010511.1_6836935_6837946_+	PRK05415, PRK05415, hypothetical protein; Provisional	NA|97aa|down_6|NC_010511.1_6837956_6838247_-	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family	NA|94aa|down_7|NC_010511.1_6838261_6838543_-	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only]	NA|391aa|down_8|NC_010511.1_6838776_6839949_-	PRK08243, PRK08243, 4-hydroxybenzoate 3-monooxygenase; Validated	NA|296aa|down_9|NC_010511.1_6840111_6840999_+	cd06999, cupin_HpaA-like_N, AraC/XylS family transcriptional regulators similar to HpaA, N-terminal cupin domain
