assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	1	193086-193283	1,1	PILER-CR,CRISPRCasFinder	no	cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Type III-B,Type III-C,Type III-A,Type III-D	CAGAGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCA,GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAAC	42,36	0	0	NA	NA	III-A:III-A	2,2	2	TypeIII-B,TypeIII-C,TypeIII-A,TypeIII-D	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|85aa|up_5|NC_015387.1_189000_189255_+,NA|77aa|down_0|NC_015387.1_193369_193600_+	csm3gr7|242aa|up_9|NC_015387.1_184060_184786_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|140aa|up_8|NC_015387.1_184785_185205_-	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2	cas10|799aa|up_7|NC_015387.1_185204_187601_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	csx1|406aa|up_6|NC_015387.1_187780_188998_+	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family	NA|85aa|up_5|NC_015387.1_189000_189255_+	NA	NA|185aa|up_4|NC_015387.1_189381_189936_+	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases	NA|509aa|up_3|NC_015387.1_189871_191398_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|98aa|up_2|NC_015387.1_191417_191711_-	cd00798, INT_XerDC_C, XerD and XerC integrases, C-terminal catalytic domains	cas1|313aa|up_1|NC_015387.1_191661_192600_+	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1	cas2|88aa|up_0|NC_015387.1_192608_192872_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|77aa|down_0|NC_015387.1_193369_193600_+	NA	NA|363aa|down_1|NC_015387.1_193710_194799_+	pfam09002, DUF1887, Domain of unknown function (DUF1887)	NA|217aa|down_2|NC_015387.1_194842_195493_+	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown]	NA|140aa|down_3|NC_015387.1_195489_195909_+	pfam01951, Archease, Archease protein family (MTH1598/TM1083)	NA|480aa|down_4|NC_015387.1_195919_197359_+	pfam01139, RtcB, tRNA-splicing ligase RtcB	NA|207aa|down_5|NC_015387.1_197374_197995_+	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive	NA|115aa|down_6|NC_015387.1_197996_198341_+	pfam11482, DUF3208, Protein of unknown function (DUF3208)	NA|151aa|down_7|NC_015387.1_198383_198836_+	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain	NA|345aa|down_8|NC_015387.1_198876_199911_+	cd05656, M42_Frv, M42 Peptidase, endoglucanases	NA|70aa|down_9|NC_015387.1_199978_200188_-	cd12222, Caa3-IV, Caa3-Type Cytochrome Oxidase subunit 4 interacts with cyt c subunits I/III
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	2	274044-277499	2,2,1	PILER-CR,CRISPRCasFinder,CRT	no	cas3,cas5,cas8c,cas7b,cas4,cas1,cas2,c2c10_CAS-V-U3	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	 Type I-U?,Type I-U,Type I-C	GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC,GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC,GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	37,37,37	2	2	274081-274119|274157-274191	NC_015387.1_2165154-2165192|NC_015387.1_2000583-2000617	I-C,III-B:I-C,III-B:I-C,III-B	47,47,47	47	TypeI-U,TypeI-U?,TypeI-C	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA,NA|87aa|down_0|NC_015387.1_277668_277929_-,NA|133aa|down_6|NC_015387.1_282427_282826_-	NA|413aa|up_9|NC_015387.1_261798_263037_+	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]	NA|599aa|up_8|NC_015387.1_263049_264846_+	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family	NA|435aa|up_7|NC_015387.1_264941_266246_+	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]	cas3|712aa|up_6|NC_015387.1_266457_268593_+	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3	cas5|230aa|up_5|NC_015387.1_268604_269294_+	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas8c|604aa|up_4|NC_015387.1_269286_271098_+	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c	cas7b|290aa|up_3|NC_015387.1_271090_271960_+	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7	cas4|193aa|up_2|NC_015387.1_271962_272541_+	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4	cas1|341aa|up_1|NC_015387.1_272537_273560_+	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG	cas2|100aa|up_0|NC_015387.1_273563_273863_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|87aa|down_0|NC_015387.1_277668_277929_-	NA	c2c10_CAS-V-U3|183aa|down_1|NC_015387.1_278514_279063_+	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain	NA|106aa|down_2|NC_015387.1_279082_279400_+	COG1715, Mrr, Restriction endonuclease [Defense mechanisms]	NA|306aa|down_3|NC_015387.1_279726_280644_+	PRK00072, hemC, porphobilinogen deaminase; Reviewed	NA|132aa|down_4|NC_015387.1_280725_281121_+	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators	NA|414aa|down_5|NC_015387.1_281121_282363_+	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism]	NA|133aa|down_6|NC_015387.1_282427_282826_-	NA	NA|163aa|down_7|NC_015387.1_282938_283427_+	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	NA|118aa|down_8|NC_015387.1_283423_283777_-	pfam02152, FolB, Dihydroneopterin aldolase	NA|259aa|down_9|NC_015387.1_283776_284553_-	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	3	522862-522953	3	CRISPRCasFinder	no		Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Orphan	CCGGGGGAGGCGATCCCGGTGGA	23	0	0	NA	NA	NA	1	1	Orphan	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA,NA|154aa|down_0|NC_015387.1_524564_525026_-	NA|367aa|up_9|NC_015387.1_513959_515060_-	pfam13546, DDE_5, DDE superfamily endonuclease	NA|48aa|up_8|NC_015387.1_515150_515294_-	PRK00701, PRK00701, divalent metal cation transporter MntH	NA|389aa|up_7|NC_015387.1_515304_516471_-	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]	NA|360aa|up_6|NC_015387.1_516470_517550_-	cd11024, CuRO_1_2DMCO_NIR_like, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase	NA|226aa|up_5|NC_015387.1_517546_518224_-	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription]	NA|360aa|up_4|NC_015387.1_518418_519498_+	PRK00591, prfA, peptide chain release factor 1; Validated	NA|160aa|up_3|NC_015387.1_519484_519964_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|233aa|up_2|NC_015387.1_520031_520730_+	sd00006, TPR, Tetratricopeptide repeat	NA|231aa|up_1|NC_015387.1_520763_521456_+	PRK08219, PRK08219, SDR family oxidoreductase	NA|136aa|up_0|NC_015387.1_521515_521923_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|154aa|down_0|NC_015387.1_524564_525026_-	NA	NA|430aa|down_1|NC_015387.1_525213_526503_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|219aa|down_2|NC_015387.1_526506_527163_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|340aa|down_3|NC_015387.1_527230_528250_-	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA	NA|335aa|down_4|NC_015387.1_528260_529265_-	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed	NA|339aa|down_5|NC_015387.1_529298_530315_-	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]	NA|300aa|down_6|NC_015387.1_530391_531291_+	PRK00089, era, GTPase Era; Reviewed	NA|294aa|down_7|NC_015387.1_531366_532248_+	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins	NA|135aa|down_8|NC_015387.1_532202_532607_-	pfam05168, HEPN, HEPN domain	NA|114aa|down_9|NC_015387.1_532611_532953_-	pfam04248, NTP_transf_9, Domain of unknown function (DUF427)
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	4	742043-742462	4	CRISPRCasFinder	no		Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Orphan	AACCAGATCGCGGACCTCACGCC	23	0	0	NA	NA	NA	6	6	Orphan	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|141aa|up_7|NC_015387.1_733298_733721_-,NA|184aa|down_7|NC_015387.1_749850_750402_+	NA|251aa|up_9|NC_015387.1_731009_731762_-	COG0327, COG0327, Uncharacterized conserved protein [Function unknown]	NA|483aa|up_8|NC_015387.1_731811_733260_-	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional	NA|141aa|up_7|NC_015387.1_733298_733721_-	NA	NA|368aa|up_6|NC_015387.1_733891_734995_+	pfam01950, FBPase_3, Fructose-1,6-bisphosphatase	NA|210aa|up_5|NC_015387.1_734978_735608_-	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism]	NA|202aa|up_4|NC_015387.1_735622_736228_-	cd01673, dNK, Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs)	NA|356aa|up_3|NC_015387.1_736238_737306_-	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|609aa|up_2|NC_015387.1_737324_739151_-	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]	NA|604aa|up_1|NC_015387.1_739150_740962_-	PRK00558, uvrC, excinuclease ABC subunit UvrC	NA|137aa|up_0|NC_015387.1_740991_741402_+	pfam11497, NADH_Oxid_Nqo15, NADH-quinone oxidoreductase chain 15	NA|273aa|down_0|NC_015387.1_742958_743777_-	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism]	NA|142aa|down_1|NC_015387.1_743894_744320_-	PRK03113, PRK03113, putative disulfide oxidoreductase; Provisional	NA|305aa|down_2|NC_015387.1_744391_745306_-	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional	NA|482aa|down_3|NC_015387.1_745302_746748_-	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|267aa|down_4|NC_015387.1_746767_747568_-	pfam02673, BacA, Bacitracin resistance protein BacA	NA|131aa|down_5|NC_015387.1_747648_748041_-	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed	NA|145aa|down_6|NC_015387.1_748040_748475_-	PRK09216, rplM, 50S ribosomal protein L13; Reviewed	NA|184aa|down_7|NC_015387.1_749850_750402_+	NA	NA|102aa|down_8|NC_015387.1_750405_750711_+	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated	NA|399aa|down_9|NC_015387.1_750857_752054_+	PRK00509, PRK00509, argininosuccinate synthase; Provisional
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	5	742571-742659	5	CRISPRCasFinder	no		Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Orphan	AACCAGATCGCGGACCTCACGCC	23	0	0	NA	NA	NA	1	1	Orphan	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|141aa|up_7|NC_015387.1_733298_733721_-,NA|184aa|down_7|NC_015387.1_749850_750402_+	NA|251aa|up_9|NC_015387.1_731009_731762_-	COG0327, COG0327, Uncharacterized conserved protein [Function unknown]	NA|483aa|up_8|NC_015387.1_731811_733260_-	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional	NA|141aa|up_7|NC_015387.1_733298_733721_-	NA	NA|368aa|up_6|NC_015387.1_733891_734995_+	pfam01950, FBPase_3, Fructose-1,6-bisphosphatase	NA|210aa|up_5|NC_015387.1_734978_735608_-	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism]	NA|202aa|up_4|NC_015387.1_735622_736228_-	cd01673, dNK, Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs)	NA|356aa|up_3|NC_015387.1_736238_737306_-	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|609aa|up_2|NC_015387.1_737324_739151_-	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]	NA|604aa|up_1|NC_015387.1_739150_740962_-	PRK00558, uvrC, excinuclease ABC subunit UvrC	NA|137aa|up_0|NC_015387.1_740991_741402_+	pfam11497, NADH_Oxid_Nqo15, NADH-quinone oxidoreductase chain 15	NA|273aa|down_0|NC_015387.1_742958_743777_-	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism]	NA|142aa|down_1|NC_015387.1_743894_744320_-	PRK03113, PRK03113, putative disulfide oxidoreductase; Provisional	NA|305aa|down_2|NC_015387.1_744391_745306_-	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional	NA|482aa|down_3|NC_015387.1_745302_746748_-	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed	NA|267aa|down_4|NC_015387.1_746767_747568_-	pfam02673, BacA, Bacitracin resistance protein BacA	NA|131aa|down_5|NC_015387.1_747648_748041_-	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed	NA|145aa|down_6|NC_015387.1_748040_748475_-	PRK09216, rplM, 50S ribosomal protein L13; Reviewed	NA|184aa|down_7|NC_015387.1_749850_750402_+	NA	NA|102aa|down_8|NC_015387.1_750405_750711_+	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated	NA|399aa|down_9|NC_015387.1_750857_752054_+	PRK00509, PRK00509, argininosuccinate synthase; Provisional
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	6	959694-963140	3,6,2	PILER-CR,CRISPRCasFinder,CRT	no	DEDDh,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Type I-E	GTAGTCCCCACGCACGTGGGGATGGACC,GTAGTCCCCACGCACGTGGGGATGGACCG,GTAGTCCCCACGCACGTGGGGATGGACCG	28,29,29	0	0	NA	NA	I-E,II-B:I-E,II-B:I-E,II-B	56,56,56	56	TypeI-E	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA,NA|164aa|down_3|NC_015387.1_967490_967982_-	NA|179aa|up_9|NC_015387.1_948148_948685_-	PRK04164, PRK04164, hypothetical protein; Provisional	WYL|323aa|up_8|NC_015387.1_948847_949816_+	pfam13280, WYL, WYL domain	cas3|925aa|up_7|NC_015387.1_949825_952600_+	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3	cas8e|490aa|up_6|NC_015387.1_953986_955456_+	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1)	cse2gr11|169aa|up_5|NC_015387.1_955452_955959_+	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional	cas7|374aa|up_4|NC_015387.1_955955_957077_+	pfam09344, Cas_CT1975, CT1975-like protein	cas5|222aa|up_3|NC_015387.1_957078_957744_+	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5)	cas6e|207aa|up_2|NC_015387.1_957718_958339_+	pfam08798, CRISPR_assoc, CRISPR associated protein	cas1|324aa|up_1|NC_015387.1_958347_959319_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|119aa|up_0|NC_015387.1_959278_959635_+	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978)	NA|628aa|down_0|NC_015387.1_963380_965264_+	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]	NA|245aa|down_1|NC_015387.1_965250_965985_+	pfam01063, Aminotran_4, Amino-transferase class IV	NA|383aa|down_2|NC_015387.1_966361_967510_+	TIGR01392, Homoserine_O-acetyltransferase, homoserine O-acetyltransferase	NA|164aa|down_3|NC_015387.1_967490_967982_-	NA	NA|197aa|down_4|NC_015387.1_967993_968584_-	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold	NA|677aa|down_5|NC_015387.1_968589_970620_-	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated	NA|375aa|down_6|NC_015387.1_970708_971833_+	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea	NA|506aa|down_7|NC_015387.1_971891_973409_+	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only]	NA|423aa|down_8|NC_015387.1_973548_974817_+	pfam11376, DUF3179, Protein of unknown function (DUF3179)	NA|123aa|down_9|NC_015387.1_974819_975188_+	pfam04134, DUF393, Protein of unknown function, DUF393
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	7	1465974-1467823	7,4,3	CRISPRCasFinder,PILER-CR,CRT	no		Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Orphan	GTTTCAAATCCCAGAAGGAACGGTGAAAAC,TTTCAAATCCCAGAAGGAACGGTGAAAAC,TTTCAAATCCCAGAAGGAACGGTGAAAACC	30,29,30	0	0	NA	NA	NA:NA:NA	27,27,27	27	Orphan	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|248aa|up_9|NC_015387.1_1455851_1456595_+,NA|93aa|down_9|NC_015387.1_1479439_1479718_+	NA|248aa|up_9|NC_015387.1_1455851_1456595_+	NA	NA|286aa|up_8|NC_015387.1_1456597_1457455_+	cd06852, GT_MraY, Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan	NA|423aa|up_7|NC_015387.1_1457451_1458720_+	TIGR01087, UDP-N-acetylmuramoylalanine--D-glutamate_ligase, UDP-N-acetylmuramoylalanine--D-glutamate ligase	NA|356aa|up_6|NC_015387.1_1458698_1459766_+	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA	NA|347aa|up_5|NC_015387.1_1459762_1460803_+	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional	NA|453aa|up_4|NC_015387.1_1460799_1462158_+	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional	NA|279aa|up_3|NC_015387.1_1462154_1462991_+	PRK14651, PRK14651, UDP-N-acetylmuramate dehydrogenase	NA|197aa|up_2|NC_015387.1_1462987_1463578_+	COG1589, FtsQ, Cell division septal protein [Cell envelope biogenesis, outer membrane]	NA|416aa|up_1|NC_015387.1_1463574_1464822_+	COG0849, ftsA, Cell division ATPase FtsA [Cell division and chromosome partitioning]	NA|357aa|up_0|NC_015387.1_1464831_1465902_+	PRK09330, PRK09330, cell division protein FtsZ; Validated	NA|123aa|down_0|NC_015387.1_1468076_1468445_-	pfam00072, Response_reg, Response regulator receiver domain	NA|251aa|down_1|NC_015387.1_1468511_1469264_-	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain	NA|1006aa|down_2|NC_015387.1_1469286_1472304_-	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed	NA|332aa|down_3|NC_015387.1_1472348_1473344_-	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	NA|374aa|down_4|NC_015387.1_1473415_1474537_+	pfam05175, MTS, Methyltransferase small domain	NA|478aa|down_5|NC_015387.1_1474592_1476026_+	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|300aa|down_6|NC_015387.1_1476258_1477158_+	PRK07340, PRK07340, delta(1)-pyrroline-2-carboxylate reductase family protein	NA|488aa|down_7|NC_015387.1_1477145_1478609_-	pfam11283, DUF3084, Protein of unknown function (DUF3084)	NA|255aa|down_8|NC_015387.1_1478618_1479383_-	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system	NA|93aa|down_9|NC_015387.1_1479439_1479718_+	NA
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	8	1919686-1919795	8	CRISPRCasFinder	no	cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,cas10,csx1,c2c9_V-U4	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Type III-D,Type III-C,Type III-A,Type III-B, Type III-C?	GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACC	37	0	0	NA	NA	III-A	1	1	TypeIII-D,TypeIII-C,TypeIII-A,TypeIII-B,TypeIII-C?	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|79aa|up_9|NC_015387.1_1908973_1909210_+,NA|434aa|down_0|NC_015387.1_1920031_1921333_+,NA|123aa|down_2|NC_015387.1_1923355_1923724_-,NA|90aa|down_4|NC_015387.1_1924521_1924791_-,NA|177aa|down_6|NC_015387.1_1925417_1925948_+	NA|79aa|up_9|NC_015387.1_1908973_1909210_+	NA	NA|268aa|up_8|NC_015387.1_1909178_1909982_-	TIGR02127, Orotidine_5'-phosphate_decarboxylase, orotidine 5'-phosphate decarboxylase, subfamily 2	cmr6gr7|359aa|up_7|NC_015387.1_1910025_1911102_-	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6	cmr5gr11|115aa|up_6|NC_015387.1_1911104_1911449_-	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5)	cmr4gr7|285aa|up_5|NC_015387.1_1911451_1912306_-	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4	cmr1gr7|414aa|up_4|NC_015387.1_1912309_1913551_-	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	cmr3gr5|373aa|up_3|NC_015387.1_1913547_1914666_-	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3	cas10|590aa|up_2|NC_015387.1_1914655_1916425_-	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10	csx1|406aa|up_1|NC_015387.1_1916491_1917709_-	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1	csx1|477aa|up_0|NC_015387.1_1917721_1919152_-	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1	NA|434aa|down_0|NC_015387.1_1920031_1921333_+	NA	c2c9_V-U4|422aa|down_1|NC_015387.1_1922012_1923278_-	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|123aa|down_2|NC_015387.1_1923355_1923724_-	NA	NA|215aa|down_3|NC_015387.1_1923720_1924365_-	cd02423, Peptidase_C39G, A sub-family of peptidase family C39	NA|90aa|down_4|NC_015387.1_1924521_1924791_-	NA	NA|54aa|down_5|NC_015387.1_1924803_1924965_-	pfam05055, DUF677, Protein of unknown function (DUF677)	NA|177aa|down_6|NC_015387.1_1925417_1925948_+	NA	NA|555aa|down_7|NC_015387.1_1926004_1927669_-	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains  present in bacteria and archaea	NA|252aa|down_8|NC_015387.1_1927836_1928592_-	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]	NA|333aa|down_9|NC_015387.1_1928669_1929668_-	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	9	1990739-1991228	9,5,10	CRISPRCasFinder,PILER-CR,CRISPRCasFinder	no		Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Orphan	AACCGGGTGCAGGACCTCACCCCCCTC,GGACCTCACCCCCCTCC,AACCGGGTGCAGGACCTCACCCCCCTC	27,17,27	0	0	NA	NA	NA:NA:NA	5,3,5	5	Orphan	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|62aa|up_7|NC_015387.1_1983096_1983282_-,NA|98aa|up_6|NC_015387.1_1983344_1983638_-,NA|69aa|down_1|NC_015387.1_1992204_1992411_+,NA|145aa|down_3|NC_015387.1_1995759_1996194_-	NA|1008aa|up_9|NC_015387.1_1979699_1982723_+	pfam10070, DUF2309, Uncharacterized protein conserved in bacteria (DUF2309)	NA|109aa|up_8|NC_015387.1_1982719_1983046_+	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism]	NA|62aa|up_7|NC_015387.1_1983096_1983282_-	NA	NA|98aa|up_6|NC_015387.1_1983344_1983638_-	NA	NA|332aa|up_5|NC_015387.1_1983837_1984833_-	sd00006, TPR, Tetratricopeptide repeat	NA|153aa|up_4|NC_015387.1_1984829_1985288_-	pfam03918, CcmH, Cytochrome C biogenesis protein	NA|177aa|up_3|NC_015387.1_1985284_1985815_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|655aa|up_2|NC_015387.1_1985811_1987776_-	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]	NA|319aa|up_1|NC_015387.1_1988054_1989011_+	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins	NA|450aa|up_0|NC_015387.1_1989069_1990419_+	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|271aa|down_0|NC_015387.1_1991382_1992195_+	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only]	NA|69aa|down_1|NC_015387.1_1992204_1992411_+	NA	NA|876aa|down_2|NC_015387.1_1992546_1995174_+	PRK00390, leuS, leucyl-tRNA synthetase; Validated	NA|145aa|down_3|NC_015387.1_1995759_1996194_-	NA	NA|73aa|down_4|NC_015387.1_1997538_1997757_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|250aa|down_5|NC_015387.1_1997804_1998554_-	pfam16575, CLP1_P, mRNA cleavage and polyadenylation factor CLP1 P-loop	NA|106aa|down_6|NC_015387.1_1998553_1998871_-	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE)	NA|128aa|down_7|NC_015387.1_1998867_1999251_-	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism]	NA|856aa|down_8|NC_015387.1_1999423_2001991_+	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB	NA|235aa|down_9|NC_015387.1_2002033_2002738_-	cd08556, GDPD, Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins
GCF_000195335.1_ASM19533v1	NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	10	2083555-2085389	6,11,4	PILER-CR,CRISPRCasFinder,CRT	no	cas6,cas8b1,cas7,cas3,cas4,cas1,cas2	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	Type I-B	GTTTCAAATCCCAGAAGGAACGGTGAAAAC,GTTTTCACCGTTCCTTCTGGGATTTGAAAC,GTTTTCACCGTTCCTTCTGGGATTTGAAAC	30,30,30	0	0	NA	NA	NA:NA:NA	27,27,27	27	TypeI-B	Cas14u_CAS-V,DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	NA|82aa|up_4|NC_015387.1_2079110_2079356_+,NA|272aa|down_9|NC_015387.1_2095769_2096585_-	NA|375aa|up_9|NC_015387.1_2073113_2074238_-	cd19981, PBP1_ABC_HAAT-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides	NA|240aa|up_8|NC_015387.1_2074251_2074971_-	COG2188, PhnF, Transcriptional regulators [Transcription]	cas6|241aa|up_7|NC_015387.1_2075134_2075857_+	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6	cas8b1|631aa|up_6|NC_015387.1_2075853_2077746_+	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802)	cas7|308aa|up_5|NC_015387.1_2077732_2078656_+	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7	NA|82aa|up_4|NC_015387.1_2079110_2079356_+	NA	cas3|759aa|up_3|NC_015387.1_2079359_2081636_+	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3	cas4|173aa|up_2|NC_015387.1_2081608_2082127_+	pfam01930, Cas_Cas4, Domain of unknown function DUF83	cas1|329aa|up_1|NC_015387.1_2082123_2083110_+	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP	cas2|88aa|up_0|NC_015387.1_2083113_2083377_+	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2	NA|399aa|down_0|NC_015387.1_2085507_2086704_-	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters	NA|354aa|down_1|NC_015387.1_2086714_2087776_-	PRK14468, PRK14468, 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA|752aa|down_2|NC_015387.1_2087785_2090041_-	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed	NA|354aa|down_3|NC_015387.1_2090119_2091181_-	TIGR01208, rmlA_long, glucose-1-phosphate thymidylylransferase, long form	NA|442aa|down_4|NC_015387.1_2091183_2092509_-	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]	NA|242aa|down_5|NC_015387.1_2092580_2093306_+	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]	NA|376aa|down_6|NC_015387.1_2093331_2094459_-	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]	NA|150aa|down_7|NC_015387.1_2094468_2094918_-	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues	NA|221aa|down_8|NC_015387.1_2095138_2095801_+	pfam00570, HRDC, HRDC domain	NA|272aa|down_9|NC_015387.1_2095769_2096585_-	NA
