assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000215105.1_ASM21510v1	NC_015588	Isoptericola variabilis 225, complete sequence	1	854201-854289	1	CRISPRCasFinder	no		csa3,DEDDh,cas3,DinG,cas4,WYL	Orphan	GTTGTCAGGGCCACGCCGCGGTATACC	27	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,DinG,cas4,WYL	NA,NA	NA|547aa|up_9|NC_015588.1_837681_839322_+	cd07778, FGGY_L-RBK_like, L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases	NA|235aa|up_8|NC_015588.1_839318_840023_+	PRK06557, PRK06557, L-ribulose-5-phosphate 4-epimerase; Validated	NA|504aa|up_7|NC_015588.1_840057_841569_+	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|1446aa|up_6|NC_015588.1_841647_845985_-	pfam07532, Big_4, Bacterial Ig-like domain (group 4)	NA|647aa|up_5|NC_015588.1_846266_848207_-	pfam07944, Glyco_hydro_127, Beta-L-arabinofuranosidase, GH127	NA|298aa|up_4|NC_015588.1_848246_849140_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|326aa|up_3|NC_015588.1_849141_850119_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|435aa|up_2|NC_015588.1_850115_851420_-	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|344aa|up_1|NC_015588.1_851596_852628_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|476aa|up_0|NC_015588.1_852756_854184_+	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|520aa|down_0|NC_015588.1_854329_855889_-	COG3534, AbfA, Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]	NA|662aa|down_1|NC_015588.1_855989_857975_+	COG3533, COG3533, Uncharacterized protein conserved in bacteria [Function unknown]	NA|359aa|down_2|NC_015588.1_857992_859069_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|223aa|down_3|NC_015588.1_859102_859771_-	COG5578, COG5578, Predicted integral membrane protein [Function unknown]	NA|456aa|down_4|NC_015588.1_859779_861147_-	cd08998, GH43_Arb43a-like, Glycosyl hydrolase family 43 protein such as Bacillus subtilis subsp	NA|287aa|down_5|NC_015588.1_861148_862009_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|327aa|down_6|NC_015588.1_862024_863005_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|452aa|down_7|NC_015588.1_863082_864438_-	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|442aa|down_8|NC_015588.1_864710_866036_+	cd14792, GH27, glycosyl hydrolase family 27 (GH27)	NA|348aa|down_9|NC_015588.1_866032_867076_+	cd08998, GH43_Arb43a-like, Glycosyl hydrolase family 43 protein such as Bacillus subtilis subsp
GCF_000215105.1_ASM21510v1	NC_015588	Isoptericola variabilis 225, complete sequence	2	1191517-1191605	2	CRISPRCasFinder	no		csa3,DEDDh,cas3,DinG,cas4,WYL	Orphan	GAGTTGTCAGGCCCACGCGCGCGTATAGG	29	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,DinG,cas4,WYL	NA,NA|128aa|down_3|NC_015588.1_1194461_1194845_+	NA|121aa|up_9|NC_015588.1_1178280_1178643_-	pfam03551, PadR, Transcriptional regulator PadR-like family	NA|301aa|up_8|NC_015588.1_1179132_1180035_-	COG2514, COG2514, Predicted ring-cleavage extradiol dioxygenase [General function prediction only]	NA|479aa|up_7|NC_015588.1_1180305_1181742_+	PRK01490, tig, trigger factor; Provisional	NA|207aa|up_6|NC_015588.1_1181995_1182616_+	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed	NA|229aa|up_5|NC_015588.1_1182704_1183391_+	PRK12553, PRK12553, ATP-dependent Clp protease proteolytic subunit; Reviewed	NA|422aa|up_4|NC_015588.1_1183553_1184819_+	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX	NA|609aa|up_3|NC_015588.1_1184885_1186712_-	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases	NA|126aa|up_2|NC_015588.1_1186825_1187203_+	PRK09239, PRK09239, chorismate mutase; Provisional	NA|417aa|up_1|NC_015588.1_1187356_1188607_+	pfam18844, baeRF_family2, Bacterial archaeo-eukaryotic release factor family 2	NA|926aa|up_0|NC_015588.1_1188681_1191459_-	NF000540, alt_ValS, valine--tRNA ligase	NA|237aa|down_0|NC_015588.1_1191667_1192378_-	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only]	NA|335aa|down_1|NC_015588.1_1192479_1193484_+	TIGR03885, putative_dehydrogenase_protein, probable non-F420 flavinoid oxidoreductase	NA|284aa|down_2|NC_015588.1_1193483_1194335_+	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional	NA|128aa|down_3|NC_015588.1_1194461_1194845_+	NA	NA|163aa|down_4|NC_015588.1_1194947_1195436_-	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS)	NA|152aa|down_5|NC_015588.1_1195580_1196036_+	pfam07452, CHRD, CHRD domain	NA|500aa|down_6|NC_015588.1_1196117_1197617_-	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent  Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold	NA|475aa|down_7|NC_015588.1_1197712_1199137_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|542aa|down_8|NC_015588.1_1199127_1200753_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|217aa|down_9|NC_015588.1_1200743_1201394_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]
GCF_000215105.1_ASM21510v1	NC_015588	Isoptericola variabilis 225, complete sequence	3	2657735-2657819	3	CRISPRCasFinder	no		csa3,DEDDh,cas3,DinG,cas4,WYL	Orphan	TCCCACGAGTTGTCAGGCCCAGGC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,DinG,cas4,WYL	NA,NA|315aa|down_1|NC_015588.1_2658337_2659282_-	NA|276aa|up_9|NC_015588.1_2646348_2647176_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|314aa|up_8|NC_015588.1_2647175_2648117_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|430aa|up_7|NC_015588.1_2648124_2649414_-	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold	NA|714aa|up_6|NC_015588.1_2649472_2651614_-	pfam02065, Melibiase, Melibiase	NA|395aa|up_5|NC_015588.1_2651676_2652861_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|153aa|up_4|NC_015588.1_2652896_2653355_+	pfam04138, GtrA, GtrA-like protein	NA|446aa|up_3|NC_015588.1_2653460_2654798_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|228aa|up_2|NC_015588.1_2654801_2655485_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|468aa|up_1|NC_015588.1_2655655_2657059_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|224aa|up_0|NC_015588.1_2657055_2657727_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|133aa|down_0|NC_015588.1_2657873_2658272_+	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|315aa|down_1|NC_015588.1_2658337_2659282_-	NA	NA|280aa|down_2|NC_015588.1_2659622_2660462_+	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]	NA|853aa|down_3|NC_015588.1_2660461_2663020_+	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]	NA|1513aa|down_4|NC_015588.1_2663090_2667629_+	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain	NA|83aa|down_5|NC_015588.1_2667767_2668016_+	pfam02467, Whib, Transcription factor WhiB	NA|494aa|down_6|NC_015588.1_2668108_2669590_-	pfam12282, H_kinase_N, Signal transduction histidine kinase	NA|170aa|down_7|NC_015588.1_2669639_2670149_+	pfam10698, DUF2505, Protein of unknown function (DUF2505)	NA|506aa|down_8|NC_015588.1_2670111_2671629_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|383aa|down_9|NC_015588.1_2671745_2672894_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]
GCF_000215105.1_ASM21510v1	NC_015588	Isoptericola variabilis 225, complete sequence	4	2729889-2729977	4	CRISPRCasFinder	no	cas3	csa3,DEDDh,cas3,DinG,cas4,WYL	Unclear	GCGCTACCTCGTGGCAGAACGCGCTACCT	29	0	0	NA	NA	NA	1	1	Unclear	csa3,DEDDh,cas3,DinG,cas4,WYL	NA|82aa|up_9|NC_015588.1_2721633_2721879_+,NA|279aa|up_4|NC_015588.1_2726240_2727077_-,NA|105aa|up_0|NC_015588.1_2729399_2729714_+,NA	NA|82aa|up_9|NC_015588.1_2721633_2721879_+	NA	NA|270aa|up_8|NC_015588.1_2721910_2722720_+	pfam12840, HTH_20, Helix-turn-helix domain	NA|204aa|up_7|NC_015588.1_2722819_2723431_+	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed	NA|126aa|up_6|NC_015588.1_2724056_2724434_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|484aa|up_5|NC_015588.1_2724710_2726162_-	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|279aa|up_4|NC_015588.1_2726240_2727077_-	NA	NA|320aa|up_3|NC_015588.1_2727379_2728339_-	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]	NA|173aa|up_2|NC_015588.1_2728377_2728896_-	COG1507, COG1507, Uncharacterized conserved protein [Function unknown]	NA|167aa|up_1|NC_015588.1_2728930_2729431_-	pfam04977, DivIC, Septum formation initiator	NA|105aa|up_0|NC_015588.1_2729399_2729714_+	NA	NA|427aa|down_0|NC_015588.1_2729986_2731267_-	PRK00077, eno, enolase; Provisional	NA|167aa|down_1|NC_015588.1_2731371_2731872_-	pfam08713, DNA_alkylation, DNA alkylation repair enzyme	cas3|1211aa|down_2|NC_015588.1_2731911_2735544_-	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]	NA|197aa|down_3|NC_015588.1_2735654_2736245_-	pfam13828, DUF4190, Domain of unknown function (DUF4190)	NA|201aa|down_4|NC_015588.1_2736294_2736897_-	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional	NA|198aa|down_5|NC_015588.1_2737249_2737843_-	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed	NA|328aa|down_6|NC_015588.1_2738323_2739307_-	PRK03092, PRK03092, ribose-phosphate diphosphokinase	NA|538aa|down_7|NC_015588.1_2739306_2740920_-	PRK14352, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	NA|211aa|down_8|NC_015588.1_2741335_2741968_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|172aa|down_9|NC_015588.1_2741997_2742513_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein
GCF_000215105.1_ASM21510v1	NC_015588	Isoptericola variabilis 225, complete sequence	5	2837207-2837301	5	CRISPRCasFinder	no		csa3,DEDDh,cas3,DinG,cas4,WYL	Orphan	CCCACGAGTTGTCAGGCTCACGCCGGGGTATACC	34	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,cas3,DinG,cas4,WYL	NA|148aa|up_6|NC_015588.1_2829602_2830046_-,NA|1091aa|up_3|NC_015588.1_2832370_2835643_-,NA|59aa|up_0|NC_015588.1_2836975_2837152_-,NA	NA|281aa|up_9|NC_015588.1_2826921_2827764_+	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]	NA|443aa|up_8|NC_015588.1_2827682_2829011_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|172aa|up_7|NC_015588.1_2829007_2829523_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|148aa|up_6|NC_015588.1_2829602_2830046_-	NA	NA|487aa|up_5|NC_015588.1_2830563_2832024_-	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]	NA|86aa|up_4|NC_015588.1_2832131_2832389_+	pfam10745, DUF2530, Protein of unknown function (DUF2530)	NA|1091aa|up_3|NC_015588.1_2832370_2835643_-	NA	NA|283aa|up_2|NC_015588.1_2835639_2836488_-	pfam11228, DUF3027, Protein of unknown function (DUF3027)	NA|128aa|up_1|NC_015588.1_2836499_2836883_-	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea	NA|59aa|up_0|NC_015588.1_2836975_2837152_-	NA	NA|810aa|down_0|NC_015588.1_2837355_2839785_+	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|560aa|down_1|NC_015588.1_2839804_2841484_+	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|332aa|down_2|NC_015588.1_2841613_2842609_+	TIGR03557, F420_G6P_family, F420-dependent oxidoreductase, G6PDH family	NA|122aa|down_3|NC_015588.1_2842634_2843000_+	COG2149, COG2149, Predicted membrane protein [Function unknown]	NA|119aa|down_4|NC_015588.1_2842996_2843353_+	COG2149, COG2149, Predicted membrane protein [Function unknown]	NA|395aa|down_5|NC_015588.1_2843418_2844603_+	pfam01594, AI-2E_transport, AI-2E family transporter	NA|708aa|down_6|NC_015588.1_2844663_2846787_+	pfam04536, TPM_phosphatase, TPM domain	NA|247aa|down_7|NC_015588.1_2846880_2847621_+	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]	NA|260aa|down_8|NC_015588.1_2847736_2848516_-	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain	NA|205aa|down_9|NC_015588.1_2848633_2849248_+	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins
