assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	1	316919-317000	1	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CACGCCGCGGTTCGTCTCCTCCAGCTCG	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|398aa|up_8|NC_017803.1_301979_303173_-,NA|230aa|up_6|NC_017803.1_305624_306314_-,NA|501aa|up_5|NC_017803.1_306343_307846_-,NA|77aa|down_6|NC_017803.1_321445_321676_+	NA|411aa|up_9|NC_017803.1_300747_301980_-	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|398aa|up_8|NC_017803.1_301979_303173_-	NA	NA|658aa|up_7|NC_017803.1_303455_305429_-	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed	NA|230aa|up_6|NC_017803.1_305624_306314_-	NA	NA|501aa|up_5|NC_017803.1_306343_307846_-	NA	NA|229aa|up_4|NC_017803.1_307842_308529_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|179aa|up_3|NC_017803.1_308525_309062_-	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|764aa|up_2|NC_017803.1_309162_311454_+	pfam13861, FLgD_tudor, FlgD Tudor-like domain	NA|1041aa|up_1|NC_017803.1_311480_314603_+	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	NA|525aa|up_0|NC_017803.1_314609_316184_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|344aa|down_0|NC_017803.1_317526_318558_-	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains	NA|135aa|down_1|NC_017803.1_318554_318959_-	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains	NA|142aa|down_2|NC_017803.1_318955_319381_-	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation	NA|287aa|down_3|NC_017803.1_319382_320243_-	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation	NA|118aa|down_4|NC_017803.1_320409_320763_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|156aa|down_5|NC_017803.1_320872_321340_+	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL	NA|77aa|down_6|NC_017803.1_321445_321676_+	NA	NA|263aa|down_7|NC_017803.1_321754_322543_-	COG5660, COG5660, Predicted integral membrane protein [Function unknown]	NA|208aa|down_8|NC_017803.1_322593_323217_-	pfam11706, zf-CGNR, CGNR zinc finger	NA|262aa|down_9|NC_017803.1_323355_324141_+	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	2	701370-701476	2	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGGCAGCGTGGGTGGCTGGCGTGGTC	27	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|133aa|up_2|NC_017803.1_697287_697686_-,NA|288aa|down_2|NC_017803.1_703319_704183_+	NA|531aa|up_9|NC_017803.1_689387_690980_+	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]	NA|152aa|up_8|NC_017803.1_690976_691432_+	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains	NA|273aa|up_7|NC_017803.1_691424_692243_+	cd01517, PAP_phosphatase, PAP-phosphatase_like domains	NA|258aa|up_6|NC_017803.1_692311_693085_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|337aa|up_5|NC_017803.1_693236_694247_+	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning]	NA|640aa|up_4|NC_017803.1_694507_696427_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|242aa|up_3|NC_017803.1_696463_697189_+	cd05233, SDR_c, classical (c) SDRs	NA|133aa|up_2|NC_017803.1_697287_697686_-	NA	NA|709aa|up_1|NC_017803.1_697997_700124_+	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair]	NA|166aa|up_0|NC_017803.1_700557_701055_-	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain	NA|102aa|down_0|NC_017803.1_702510_702816_+	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156	NA|71aa|down_1|NC_017803.1_702877_703090_+	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism]	NA|288aa|down_2|NC_017803.1_703319_704183_+	NA	NA|381aa|down_3|NC_017803.1_704168_705311_-	pfam13679, Methyltransf_32, Methyltransferase domain	NA|649aa|down_4|NC_017803.1_706538_708485_-	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]	NA|75aa|down_5|NC_017803.1_708701_708926_-	pfam11305, DUF3107, Protein of unknown function (DUF3107)	NA|220aa|down_6|NC_017803.1_708965_709625_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|521aa|down_7|NC_017803.1_710065_711628_+	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|320aa|down_8|NC_017803.1_711627_712587_+	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|294aa|down_9|NC_017803.1_712638_713520_+	pfam11350, DUF3152, Protein of unknown function (DUF3152)
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	3	737746-737848	3	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGTGACCGGTCCTGCTCCGACCC	25	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|302aa|up_7|NC_017803.1_729573_730479_-,NA	NA|179aa|up_9|NC_017803.1_727720_728257_+	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB	NA|434aa|up_8|NC_017803.1_728267_729569_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|302aa|up_7|NC_017803.1_729573_730479_-	NA	NA|179aa|up_6|NC_017803.1_730478_731015_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|207aa|up_5|NC_017803.1_731079_731700_+	pfam00329, Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit	NA|320aa|up_4|NC_017803.1_731699_732659_+	pfam00146, NADHdh, NADH dehydrogenase	NA|200aa|up_3|NC_017803.1_732761_733361_+	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI	NA|190aa|up_2|NC_017803.1_733357_733927_+	pfam00499, Oxidored_q3, NADH-ubiquinone/plastoquinone oxidoreductase chain 6	NA|119aa|up_1|NC_017803.1_733926_734283_+	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK	NA|638aa|up_0|NC_017803.1_734279_736193_+	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed	NA|485aa|down_0|NC_017803.1_737903_739358_+	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN	NA|302aa|down_1|NC_017803.1_739770_740676_+	PRK03072, PRK03072, heat shock protein HtpX; Provisional	NA|142aa|down_2|NC_017803.1_740929_741355_+	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|336aa|down_3|NC_017803.1_741411_742419_+	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1	NA|271aa|down_4|NC_017803.1_742438_743251_+	COG3393, COG3393, Predicted acetyltransferase [General function prediction only]	NA|203aa|down_5|NC_017803.1_743295_743904_+	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown]	NA|101aa|down_6|NC_017803.1_743925_744228_+	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase	NA|186aa|down_7|NC_017803.1_744686_745244_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|330aa|down_8|NC_017803.1_747347_748337_+	pfam01636, APH, Phosphotransferase enzyme family	NA|164aa|down_9|NC_017803.1_748999_749491_+	cd11740, YajQ_like, Proteins similar to Escherichia coli YajQ
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	4	1175160-1175321	1	CRT	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTCGGCTCGCCGGCAGCC	18	0	0	NA	NA	NA	4	4	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|111aa|down_2|NC_017803.1_1177085_1177418_+,NA|350aa|down_4|NC_017803.1_1177850_1178900_+,NA|470aa|down_5|NC_017803.1_1178896_1180306_+	NA|262aa|up_9|NC_017803.1_1161633_1162419_-	pfam06750, DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain	NA|169aa|up_8|NC_017803.1_1162573_1163080_-	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]	NA|412aa|up_7|NC_017803.1_1163182_1164418_-	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]	NA|374aa|up_6|NC_017803.1_1164420_1165542_-	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]	NA|556aa|up_5|NC_017803.1_1165622_1167290_-	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB	NA|324aa|up_4|NC_017803.1_1167349_1168321_-	PRK09393, ftrA, transcriptional activator FtrA; Provisional	NA|428aa|up_3|NC_017803.1_1168374_1169658_+	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters	NA|105aa|up_2|NC_017803.1_1169771_1170086_-	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|807aa|up_1|NC_017803.1_1170180_1172601_+	pfam13424, TPR_12, Tetratricopeptide repeat	NA|560aa|up_0|NC_017803.1_1172602_1174282_-	cd01948, EAL, EAL domain	NA|46aa|down_0|NC_017803.1_1176213_1176351_-	TIGR04268, FxSxx-COOH, FXSXX-COOH protein	NA|158aa|down_1|NC_017803.1_1176562_1177036_+	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family	NA|111aa|down_2|NC_017803.1_1177085_1177418_+	NA	NA|95aa|down_3|NC_017803.1_1177438_1177723_-	pfam04248, NTP_transf_9, Domain of unknown function (DUF427)	NA|350aa|down_4|NC_017803.1_1177850_1178900_+	NA	NA|470aa|down_5|NC_017803.1_1178896_1180306_+	NA	NA|596aa|down_6|NC_017803.1_1180507_1182295_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|281aa|down_7|NC_017803.1_1182873_1183716_-	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal	NA|337aa|down_8|NC_017803.1_1184273_1185284_-	pfam14350, Beta_protein, Beta protein	NA|432aa|down_9|NC_017803.1_1185320_1186616_-	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	5	1847555-1847630	4	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CTCGTCGTCCGCCGCTGATCGTCTT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|225aa|up_8|NC_017803.1_1831586_1832261_-,NA	NA|193aa|up_9|NC_017803.1_1831011_1831590_-	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase	NA|225aa|up_8|NC_017803.1_1831586_1832261_-	NA	NA|268aa|up_7|NC_017803.1_1832257_1833061_-	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs	NA|650aa|up_6|NC_017803.1_1833146_1835096_+	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|353aa|up_5|NC_017803.1_1836460_1837519_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|148aa|up_4|NC_017803.1_1838757_1839201_+	pfam18726, HEPN_SAV_6107, SAV_6107-like HEPN	NA|569aa|up_3|NC_017803.1_1841183_1842890_+	cd03468, PolY_like, DNA Polymerase Y-family	NA|1135aa|up_2|NC_017803.1_1842902_1846307_+	PRK05672, dnaE2, error-prone DNA polymerase; Validated	NA|125aa|up_1|NC_017803.1_1846349_1846724_+	pfam00720, SSI, Subtilisin inhibitor-like	NA|249aa|up_0|NC_017803.1_1846773_1847520_+	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA|131aa|down_0|NC_017803.1_1849061_1849454_+	pfam11239, DUF3040, Protein of unknown function (DUF3040)	NA|822aa|down_1|NC_017803.1_1850116_1852582_-	pfam01841, Transglut_core, Transglutaminase-like superfamily	NA|433aa|down_2|NC_017803.1_1852578_1853877_-	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]	NA|346aa|down_3|NC_017803.1_1853879_1854917_-	COG0714, COG0714, MoxR-like ATPases [General function prediction only]	NA|929aa|down_4|NC_017803.1_1855327_1858114_+	PRK00390, leuS, leucyl-tRNA synthetase; Validated	NA|238aa|down_5|NC_017803.1_1858272_1858986_-	COG0398, COG0398, Uncharacterized conserved protein [Function unknown]	NA|238aa|down_6|NC_017803.1_1859047_1859761_-	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only]	NA|407aa|down_7|NC_017803.1_1859776_1860997_-	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]	NA|266aa|down_8|NC_017803.1_1861600_1862398_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|144aa|down_9|NC_017803.1_1863232_1863664_+	PRK00326, PRK00326, transcriptional regulator MraZ
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	6	2214086-2214167	5	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCCGTGATCGATGCGCTGCGGGGCTGAA	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|52aa|up_9|NC_017803.1_2202019_2202175_-,NA|202aa|up_6|NC_017803.1_2203333_2203939_+,NA|154aa|up_5|NC_017803.1_2204000_2204462_+,NA|347aa|up_4|NC_017803.1_2204554_2205595_+,NA|129aa|down_0|NC_017803.1_2214497_2214884_+,NA|261aa|down_2|NC_017803.1_2216820_2217603_-,NA|166aa|down_9|NC_017803.1_2223935_2224433_-	NA|52aa|up_9|NC_017803.1_2202019_2202175_-	NA	NA|195aa|up_8|NC_017803.1_2202173_2202758_+	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|115aa|up_7|NC_017803.1_2202972_2203317_+	COG1378, COG1378, Predicted transcriptional regulators [Transcription]	NA|202aa|up_6|NC_017803.1_2203333_2203939_+	NA	NA|154aa|up_5|NC_017803.1_2204000_2204462_+	NA	NA|347aa|up_4|NC_017803.1_2204554_2205595_+	NA	NA|259aa|up_3|NC_017803.1_2205839_2206616_-	pfam13539, Peptidase_M15_4, D-alanyl-D-alanine carboxypeptidase	NA|1690aa|up_2|NC_017803.1_2206892_2211962_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|97aa|up_1|NC_017803.1_2212166_2212457_+	pfam10825, DUF2752, Protein of unknown function (DUF2752)	NA|180aa|up_0|NC_017803.1_2212471_2213011_+	pfam06271, RDD, RDD family	NA|129aa|down_0|NC_017803.1_2214497_2214884_+	NA	NA|424aa|down_1|NC_017803.1_2215552_2216824_-	PLN02856, PLN02856, fumarylacetoacetase	NA|261aa|down_2|NC_017803.1_2216820_2217603_-	NA	NA|392aa|down_3|NC_017803.1_2217797_2218973_-	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|367aa|down_4|NC_017803.1_2219288_2220389_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|399aa|down_5|NC_017803.1_2220339_2221536_-	PRK07337, PRK07337, pyridoxal phosphate-dependent aminotransferase	NA|201aa|down_6|NC_017803.1_2221776_2222379_+	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|159aa|down_7|NC_017803.1_2222415_2222892_-	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|267aa|down_8|NC_017803.1_2223138_2223939_+	TIGR02764, Probable_polysaccharide_deacetylase_PdaB, polysaccharide deacetylase family sporulation protein PdaB	NA|166aa|down_9|NC_017803.1_2223935_2224433_-	NA
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	7	2648119-2648307	6	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCGGGTCGGCGGCGGACTCGCGCCCGA	27	0	0	NA	NA	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA	NA|535aa|up_9|NC_017803.1_2636082_2637687_-	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]	NA|397aa|up_8|NC_017803.1_2637691_2638882_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|385aa|up_7|NC_017803.1_2639080_2640235_+	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains	NA|129aa|up_6|NC_017803.1_2640288_2640675_+	pfam01627, Hpt, Hpt domain	NA|384aa|up_5|NC_017803.1_2640683_2641835_-	TIGR02635, putative_xylose_isomerase, L-rhamnose isomerase, Streptomyces subtype	NA|344aa|up_4|NC_017803.1_2641831_2642863_-	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins	NA|319aa|up_3|NC_017803.1_2642859_2643816_-	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins	NA|500aa|up_2|NC_017803.1_2643812_2645312_-	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]	NA|343aa|up_1|NC_017803.1_2645316_2646345_-	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs	NA|140aa|up_0|NC_017803.1_2647092_2647512_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|287aa|down_0|NC_017803.1_2648993_2649854_+	pfam12277, DUF3618, Protein of unknown function (DUF3618)	NA|309aa|down_1|NC_017803.1_2649975_2650902_-	pfam00459, Inositol_P, Inositol monophosphatase family	NA|527aa|down_2|NC_017803.1_2650900_2652481_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|200aa|down_3|NC_017803.1_2652461_2653061_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|443aa|down_4|NC_017803.1_2653118_2654447_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|497aa|down_5|NC_017803.1_2654507_2655998_+	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2	NA|445aa|down_6|NC_017803.1_2656009_2657344_+	PRK06062, PRK06062, hypothetical protein; Provisional	NA|479aa|down_7|NC_017803.1_2657475_2658912_+	PRK13473, PRK13473, aminobutyraldehyde dehydrogenase	NA|386aa|down_8|NC_017803.1_2658962_2660120_+	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|403aa|down_9|NC_017803.1_2660161_2661370_+	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	8	2889113-2889207	7	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCTGGCCGGCGCGGCCCGCGGGG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|251aa|up_3|NC_017803.1_2882943_2883696_+,NA|113aa|down_9|NC_017803.1_2898398_2898737_-	NA|132aa|up_9|NC_017803.1_2878591_2878987_-	pfam06150, ChaB, ChaB	NA|283aa|up_8|NC_017803.1_2879013_2879862_-	COG2146, {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases [Inorganic ion transport and metabolism / General function prediction only]	NA|115aa|up_7|NC_017803.1_2880006_2880351_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|257aa|up_6|NC_017803.1_2880384_2881155_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|313aa|up_5|NC_017803.1_2881126_2882065_+	TIGR03557, F420_G6P_family, F420-dependent oxidoreductase, G6PDH family	NA|170aa|up_4|NC_017803.1_2882363_2882873_+	cd12108, Hr-like, Hemerythrin-like domain	NA|251aa|up_3|NC_017803.1_2882943_2883696_+	NA	NA|333aa|up_2|NC_017803.1_2884445_2885444_-	pfam00665, rve, Integrase core domain	NA|267aa|up_1|NC_017803.1_2885955_2886756_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|345aa|up_0|NC_017803.1_2886836_2887871_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|119aa|down_0|NC_017803.1_2889551_2889908_+	pfam06993, DUF1304, Protein of unknown function (DUF1304)	NA|689aa|down_1|NC_017803.1_2890305_2892372_+	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only]	NA|321aa|down_2|NC_017803.1_2892680_2893643_+	cd08998, GH43_Arb43a-like, Glycosyl hydrolase family 43 protein such as Bacillus subtilis subsp	NA|154aa|down_3|NC_017803.1_2893777_2894239_+	COG2128, COG2128, Uncharacterized conserved protein [Function unknown]	NA|96aa|down_4|NC_017803.1_2894305_2894593_+	PRK10457, PRK10457, hypothetical protein; Provisional	NA|154aa|down_5|NC_017803.1_2894606_2895068_+	pfam13376, OmdA, Bacteriocin-protection, YdeI or OmpD-Associated	NA|227aa|down_6|NC_017803.1_2895080_2895761_-	pfam05719, GPP34, Golgi phosphoprotein 3 (GPP34)	NA|330aa|down_7|NC_017803.1_2895772_2896762_-	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion]	NA|469aa|down_8|NC_017803.1_2896754_2898161_-	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|113aa|down_9|NC_017803.1_2898398_2898737_-	NA
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	9	2921228-2921340	8	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCGCGAGGCGAGGCGCGGCATGCTGCGCGAGGCGAGGCG	39	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|587aa|up_6|NC_017803.1_2912715_2914476_+,NA|153aa|up_4|NC_017803.1_2916348_2916807_-,NA|72aa|up_2|NC_017803.1_2919124_2919340_+,NA|124aa|down_3|NC_017803.1_2925010_2925382_+,NA|142aa|down_7|NC_017803.1_2927848_2928274_+	NA|332aa|up_9|NC_017803.1_2907827_2908823_+	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]	NA|673aa|up_8|NC_017803.1_2908819_2910838_+	pfam01841, Transglut_core, Transglutaminase-like superfamily	NA|585aa|up_7|NC_017803.1_2910854_2912609_-	COG0658, ComEC, Predicted membrane metal-binding protein [General function prediction only]	NA|587aa|up_6|NC_017803.1_2912715_2914476_+	NA	NA|580aa|up_5|NC_017803.1_2914528_2916268_+	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional	NA|153aa|up_4|NC_017803.1_2916348_2916807_-	NA	NA|281aa|up_3|NC_017803.1_2918217_2919060_+	COG0583, LysR, Transcriptional regulator [Transcription]	NA|72aa|up_2|NC_017803.1_2919124_2919340_+	NA	NA|192aa|up_1|NC_017803.1_2919453_2920029_+	cd01043, DPS, DPS protein, ferritin-like diiron-binding domain	NA|288aa|up_0|NC_017803.1_2920083_2920947_-	cd05355, SDR_c1, classical (c) SDR, subgroup 1	NA|504aa|down_0|NC_017803.1_2921701_2923213_+	COG3866, PelB, Pectate lyase [Carbohydrate transport and metabolism]	NA|306aa|down_1|NC_017803.1_2923216_2924134_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|182aa|down_2|NC_017803.1_2924341_2924887_+	PRK00150, def, peptide deformylase; Reviewed	NA|124aa|down_3|NC_017803.1_2925010_2925382_+	NA	NA|174aa|down_4|NC_017803.1_2925501_2926023_+	pfam12079, DUF3558, Protein of unknown function (DUF3558)	NA|158aa|down_5|NC_017803.1_2926104_2926578_+	smart00903, Flavin_Reduct, Flavin reductase like domain	NA|408aa|down_6|NC_017803.1_2926597_2927821_+	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA)	NA|142aa|down_7|NC_017803.1_2927848_2928274_+	NA	NA|83aa|down_8|NC_017803.1_2928401_2928650_-	pfam11239, DUF3040, Protein of unknown function (DUF3040)	NA|590aa|down_9|NC_017803.1_2928740_2930510_+	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	10	3230366-3230450	9	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CAGTCACCGGGCTCAGACACCGG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|74aa|up_3|NC_017803.1_3226241_3226463_+,NA|315aa|up_2|NC_017803.1_3226466_3227411_+,NA|89aa|down_0|NC_017803.1_3233057_3233324_+	NA|641aa|up_9|NC_017803.1_3216998_3218921_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|186aa|up_8|NC_017803.1_3219249_3219807_+	pfam01872, RibD_C, RibD C-terminal domain	NA|437aa|up_7|NC_017803.1_3219956_3221267_-	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD)	NA|349aa|up_6|NC_017803.1_3221367_3222414_-	pfam06224, HTH_42, Winged helix DNA-binding domain	NA|543aa|up_5|NC_017803.1_3222477_3224106_-	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed	NA|647aa|up_4|NC_017803.1_3224245_3226186_+	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]	NA|74aa|up_3|NC_017803.1_3226241_3226463_+	NA	NA|315aa|up_2|NC_017803.1_3226466_3227411_+	NA	NA|365aa|up_1|NC_017803.1_3227686_3228781_-	COG4124, ManB, Beta-mannanase [Carbohydrate transport and metabolism]	NA|383aa|up_0|NC_017803.1_3228911_3230060_+	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19)	NA|89aa|down_0|NC_017803.1_3233057_3233324_+	NA	NA|767aa|down_1|NC_017803.1_3233627_3235928_+	pfam05547, Peptidase_M6, Immune inhibitor A peptidase M6	NA|245aa|down_2|NC_017803.1_3235897_3236632_-	pfam04199, Cyclase, Putative cyclase	NA|220aa|down_3|NC_017803.1_3236652_3237312_+	COG0789, SoxR, Predicted transcriptional regulators [Transcription]	NA|888aa|down_4|NC_017803.1_3237308_3239972_+	TIGR03788, marine_srt_targ, marine proteobacterial sortase target protein	NA|422aa|down_5|NC_017803.1_3240160_3241426_+	pfam00872, Transposase_mut, Transposase, Mutator family	NA|144aa|down_6|NC_017803.1_3242757_3243189_+	cd00161, RICIN, Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication	NA|532aa|down_7|NC_017803.1_3243582_3245178_-	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]	NA|635aa|down_8|NC_017803.1_3245266_3247171_-	COG1620, LldP, L-lactate permease [Energy production and conversion]	NA|640aa|down_9|NC_017803.1_3247392_3249312_-	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	11	3451122-3451274	10	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCTGCCGCGGAGGCCGAGCGGCAGCGG	27	0	0	NA	NA	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|342aa|up_8|NC_017803.1_3433406_3434432_-,NA|323aa|up_2|NC_017803.1_3445012_3445981_+,NA	NA|749aa|up_9|NC_017803.1_3430880_3433127_+	PRK11249, katE, hydroperoxidase II; Provisional	NA|342aa|up_8|NC_017803.1_3433406_3434432_-	NA	NA|131aa|up_7|NC_017803.1_3434585_3434978_-	PRK03624, PRK03624, putative acetyltransferase; Provisional	NA|999aa|up_6|NC_017803.1_3434986_3437983_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|813aa|up_5|NC_017803.1_3438282_3440721_+	sd00006, TPR, Tetratricopeptide repeat	NA|983aa|up_4|NC_017803.1_3440722_3443671_+	pfam00931, NB-ARC, NB-ARC domain	NA|459aa|up_3|NC_017803.1_3443667_3445044_+	pfam12770, CHAT, CHAT domain	NA|323aa|up_2|NC_017803.1_3445012_3445981_+	NA	NA|342aa|up_1|NC_017803.1_3445986_3447012_-	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed	NA|731aa|up_0|NC_017803.1_3447580_3449773_+	PRK15061, PRK15061, catalase/peroxidase	NA|361aa|down_0|NC_017803.1_3452356_3453439_+	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment	NA|324aa|down_1|NC_017803.1_3453654_3454626_+	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins	NA|246aa|down_2|NC_017803.1_3454891_3455629_+	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071)	NA|211aa|down_3|NC_017803.1_3455768_3456401_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|631aa|down_4|NC_017803.1_3456473_3458366_+	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA	NA|512aa|down_5|NC_017803.1_3458401_3459937_+	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain	NA|624aa|down_6|NC_017803.1_3459936_3461808_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|381aa|down_7|NC_017803.1_3461809_3462952_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|397aa|down_8|NC_017803.1_3462945_3464136_-	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase	NA|547aa|down_9|NC_017803.1_3464331_3465972_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	12	4385391-4385505	11	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CGGGTTCGCGCCGCCGTCGGCCGGGCCCTCG	31	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|288aa|up_9|NC_017803.1_4375337_4376201_+,NA|204aa|up_8|NC_017803.1_4376222_4376834_-,NA|206aa|up_7|NC_017803.1_4377053_4377671_+,NA|347aa|up_5|NC_017803.1_4378464_4379505_-,NA|164aa|up_2|NC_017803.1_4382363_4382855_+,NA|153aa|down_1|NC_017803.1_4386873_4387332_+,NA|146aa|down_3|NC_017803.1_4389972_4390410_+,NA|144aa|down_7|NC_017803.1_4392222_4392654_-,NA|76aa|down_8|NC_017803.1_4392671_4392899_-,NA|139aa|down_9|NC_017803.1_4392907_4393324_-	NA|288aa|up_9|NC_017803.1_4375337_4376201_+	NA	NA|204aa|up_8|NC_017803.1_4376222_4376834_-	NA	NA|206aa|up_7|NC_017803.1_4377053_4377671_+	NA	NA|224aa|up_6|NC_017803.1_4377667_4378339_+	pfam13761, DUF4166, Domain of unknown function (DUF4166)	NA|347aa|up_5|NC_017803.1_4378464_4379505_-	NA	NA|172aa|up_4|NC_017803.1_4379684_4380200_-	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|319aa|up_3|NC_017803.1_4380335_4381292_+	cd03138, GATase1_AraC_2, AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain	NA|164aa|up_2|NC_017803.1_4382363_4382855_+	NA	NA|391aa|up_1|NC_017803.1_4382967_4384140_-	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|389aa|up_0|NC_017803.1_4384191_4385358_-	pfam08007, Cupin_4, Cupin superfamily protein	NA|390aa|down_0|NC_017803.1_4385638_4386808_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|153aa|down_1|NC_017803.1_4386873_4387332_+	NA	NA|877aa|down_2|NC_017803.1_4387342_4389973_+	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp	NA|146aa|down_3|NC_017803.1_4389972_4390410_+	NA	NA|139aa|down_4|NC_017803.1_4390406_4390823_+	pfam06271, RDD, RDD family	NA|350aa|down_5|NC_017803.1_4390819_4391869_+	PRK13517, PRK13517, glutamate--cysteine ligase	NA|92aa|down_6|NC_017803.1_4391942_4392218_-	pfam09851, SHOCT, Short C-terminal domain	NA|144aa|down_7|NC_017803.1_4392222_4392654_-	NA	NA|76aa|down_8|NC_017803.1_4392671_4392899_-	NA	NA|139aa|down_9|NC_017803.1_4392907_4393324_-	NA
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	13	5588003-5588223	12	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGCGGCGGGACGATGCGCTGCCGGGGCG	29	1	1	5588176-5588194	NC_017803.1_5835165-5835183	NA	4	4	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|81aa|up_0|NC_017803.1_5586518_5586761_+,NA|102aa|down_0|NC_017803.1_5590146_5590452_-,NA|54aa|down_1|NC_017803.1_5590915_5591077_-	NA|416aa|up_9|NC_017803.1_5574368_5575616_-	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism]	NA|512aa|up_8|NC_017803.1_5575612_5577148_-	PRK13549, PRK13549, xylose transporter ATP-binding subunit; Provisional	NA|358aa|up_7|NC_017803.1_5577218_5578292_-	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system	NA|496aa|up_6|NC_017803.1_5578372_5579860_-	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|328aa|up_5|NC_017803.1_5580195_5581179_-	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators	NA|474aa|up_4|NC_017803.1_5581349_5582771_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|141aa|up_3|NC_017803.1_5582767_5583190_+	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|510aa|up_2|NC_017803.1_5583084_5584614_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|384aa|up_1|NC_017803.1_5585158_5586310_-	cd03814, GT4-like, glycosyltransferase family 4 proteins	NA|81aa|up_0|NC_017803.1_5586518_5586761_+	NA	NA|102aa|down_0|NC_017803.1_5590146_5590452_-	NA	NA|54aa|down_1|NC_017803.1_5590915_5591077_-	NA	NA|517aa|down_2|NC_017803.1_5592964_5594515_+	COG0457, NrfG, FOG: TPR repeat [General function prediction only]	NA|349aa|down_3|NC_017803.1_5594498_5595545_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|273aa|down_4|NC_017803.1_5595585_5596404_-	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism]	NA|395aa|down_5|NC_017803.1_5596437_5597622_-	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB	NA|229aa|down_6|NC_017803.1_5597618_5598305_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|451aa|down_7|NC_017803.1_5598301_5599654_-	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit	NA|237aa|down_8|NC_017803.1_5599723_5600434_-	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|255aa|down_9|NC_017803.1_5600622_5601387_-	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	14	5885541-5885635	13	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGACCGGCGGAACCGTCGCCG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|185aa|down_0|NC_017803.1_5885671_5886226_+,NA|225aa|down_7|NC_017803.1_5891318_5891993_-	NA|448aa|up_9|NC_017803.1_5874018_5875362_-	COG3866, PelB, Pectate lyase [Carbohydrate transport and metabolism]	NA|112aa|up_8|NC_017803.1_5875447_5875783_-	cd06988, cupin_DddK, Dimethylsulfoniopropionate lyase DddK and related proteins, cupin domain	NA|366aa|up_7|NC_017803.1_5875760_5876858_-	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]	NA|485aa|up_6|NC_017803.1_5876954_5878409_-	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]	NA|470aa|up_5|NC_017803.1_5878405_5879815_-	PRK02925, PRK02925, glucuronate isomerase; Reviewed	NA|442aa|up_4|NC_017803.1_5879811_5881137_-	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]	NA|342aa|up_3|NC_017803.1_5881314_5882340_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|426aa|up_2|NC_017803.1_5882349_5883627_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|325aa|up_1|NC_017803.1_5883632_5884607_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|278aa|up_0|NC_017803.1_5884607_5885441_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|185aa|down_0|NC_017803.1_5885671_5886226_+	NA	NA|156aa|down_1|NC_017803.1_5886334_5886802_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|373aa|down_2|NC_017803.1_5886942_5888061_+	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains	NA|238aa|down_3|NC_017803.1_5888257_5888971_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|61aa|down_4|NC_017803.1_5889238_5889421_-	PRK14236, PRK14236, phosphate transporter ATP-binding protein; Provisional	NA|216aa|down_5|NC_017803.1_5889433_5890081_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|418aa|down_6|NC_017803.1_5890068_5891322_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|225aa|down_7|NC_017803.1_5891318_5891993_-	NA	NA|362aa|down_8|NC_017803.1_5892067_5893153_-	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|369aa|down_9|NC_017803.1_5893340_5894447_+	cd06216, FNR_iron_sulfur_binding_2, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	15	6195201-6195314	14	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGGCCCGCAGAGGAATCCGGACGCGCC	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|91aa|up_9|NC_017803.1_6184765_6185038_-,NA|99aa|up_8|NC_017803.1_6185036_6185333_+,NA|408aa|up_7|NC_017803.1_6185523_6186747_-,NA|335aa|down_3|NC_017803.1_6200209_6201214_-,NA|140aa|down_6|NC_017803.1_6203217_6203637_-	NA|91aa|up_9|NC_017803.1_6184765_6185038_-	NA	NA|99aa|up_8|NC_017803.1_6185036_6185333_+	NA	NA|408aa|up_7|NC_017803.1_6185523_6186747_-	NA	NA|367aa|up_6|NC_017803.1_6186784_6187885_-	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn)	NA|220aa|up_5|NC_017803.1_6187874_6188534_-	pfam02397, Bac_transf, Bacterial sugar transferase	NA|419aa|up_4|NC_017803.1_6188546_6189803_-	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]	NA|651aa|up_3|NC_017803.1_6189832_6191785_-	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]	NA|374aa|up_2|NC_017803.1_6192152_6193274_+	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins	NA|188aa|up_1|NC_017803.1_6193206_6193770_-	pfam04892, VanZ, VanZ like family	NA|202aa|up_0|NC_017803.1_6194062_6194668_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|523aa|down_0|NC_017803.1_6195431_6197000_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|204aa|down_1|NC_017803.1_6197136_6197748_-	pfam02517, Abi, CAAX protease self-immunity	NA|639aa|down_2|NC_017803.1_6198096_6200013_+	PRK13351, PRK13351, elongation factor G-like protein	NA|335aa|down_3|NC_017803.1_6200209_6201214_-	NA	NA|404aa|down_4|NC_017803.1_6201415_6202627_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|222aa|down_5|NC_017803.1_6202545_6203211_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|140aa|down_6|NC_017803.1_6203217_6203637_-	NA	NA|456aa|down_7|NC_017803.1_6203703_6205071_-	TIGR03356, BGL, beta-galactosidase	NA|299aa|down_8|NC_017803.1_6205067_6205964_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|305aa|down_9|NC_017803.1_6205970_6206885_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	16	6284014-6284102	15	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGCACCGCAACATCGGCCACGGCC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|141aa|up_4|NC_017803.1_6279968_6280391_+,NA|572aa|down_9|NC_017803.1_6300039_6301755_+	NA|528aa|up_9|NC_017803.1_6272273_6273857_+	PRK12853, PRK12853, glucose-6-phosphate dehydrogenase	NA|529aa|up_8|NC_017803.1_6273845_6275432_-	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|880aa|up_7|NC_017803.1_6275435_6278075_-	PRK08257, PRK08257, acetyl-CoA acetyltransferase; Validated	NA|199aa|up_6|NC_017803.1_6278171_6278768_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|384aa|up_5|NC_017803.1_6278770_6279922_+	cd01160, LCAD, Long chain acyl-CoA dehydrogenase	NA|141aa|up_4|NC_017803.1_6279968_6280391_+	NA	NA|125aa|up_3|NC_017803.1_6280413_6280788_-	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown]	NA|151aa|up_2|NC_017803.1_6281012_6281465_-	pfam03780, Asp23, Asp23 family, cell envelope-related function	NA|114aa|up_1|NC_017803.1_6281633_6281975_+	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3	NA|665aa|up_0|NC_017803.1_6281967_6283962_-	COG3276, SelB, Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]	NA|429aa|down_0|NC_017803.1_6284253_6285540_-	PRK04311, PRK04311, selenocysteine synthase; Provisional	NA|258aa|down_1|NC_017803.1_6285803_6286577_+	cd05483, retropepsin_like_bacteria, Bacterial aspartate proteases, retropepsin-like protease family	NA|403aa|down_2|NC_017803.1_6286888_6288097_-	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism]	NA|779aa|down_3|NC_017803.1_6288255_6290592_-	pfam13229, Beta_helix, Right handed beta helix region	NA|331aa|down_4|NC_017803.1_6291048_6292041_+	TIGR00476, selenide_water_dikinase, selenium donor protein	NA|676aa|down_5|NC_017803.1_6292078_6294106_-	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|304aa|down_6|NC_017803.1_6294336_6295248_-	pfam03916, NrfD, Polysulphide reductase, NrfD	NA|306aa|down_7|NC_017803.1_6295268_6296186_-	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins	NA|1067aa|down_8|NC_017803.1_6296187_6299388_-	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit	NA|572aa|down_9|NC_017803.1_6300039_6301755_+	NA
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	17	7162291-7162381	16	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGCGGACCGCGAGCGGCCCGCCCTCCGAA	29	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|84aa|down_1|NC_017803.1_7163507_7163759_-	NA|413aa|up_9|NC_017803.1_7149188_7150427_-	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase	NA|306aa|up_8|NC_017803.1_7150429_7151347_+	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase	NA|543aa|up_7|NC_017803.1_7151370_7152999_-	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin	NA|446aa|up_6|NC_017803.1_7153073_7154411_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|419aa|up_5|NC_017803.1_7154407_7155664_+	PRK09237, PRK09237, amidohydrolase/deacetylase family metallohydrolase	NA|127aa|up_4|NC_017803.1_7155663_7156044_+	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis]	NA|101aa|up_3|NC_017803.1_7158883_7159186_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|136aa|up_2|NC_017803.1_7159182_7159590_+	pfam00699, Urease_beta, Urease beta subunit	NA|523aa|up_1|NC_017803.1_7159586_7161155_+	PRK13206, ureC, urease subunit alpha; Reviewed	NA|348aa|up_0|NC_017803.1_7161164_7162208_-	cd08260, Zn_ADH6, Alcohol dehydrogenases of the MDR family	NA|301aa|down_0|NC_017803.1_7162389_7163292_-	COG1191, FliA, DNA-directed RNA polymerase specialized sigma subunit [Transcription]	NA|84aa|down_1|NC_017803.1_7163507_7163759_-	NA	NA|616aa|down_2|NC_017803.1_7164091_7165939_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|296aa|down_3|NC_017803.1_7168918_7169806_-	TIGR02069, cyanophycinase, cyanophycinase	NA|163aa|down_4|NC_017803.1_7169960_7170449_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|174aa|down_5|NC_017803.1_7170505_7171027_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|437aa|down_6|NC_017803.1_7171056_7172367_-	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed	NA|233aa|down_7|NC_017803.1_7172387_7173086_-	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|290aa|down_8|NC_017803.1_7173234_7174104_+	cd00317, cyclophilin, cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases	NA|277aa|down_9|NC_017803.1_7174133_7174964_+	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	18	7827726-7827806	17	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTGCTCTGACCGCGACCACCCACGGA	26	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|570aa|down_5|NC_017803.1_7834703_7836413_+	NA|266aa|up_9|NC_017803.1_7819125_7819923_-	pfam00303, Thymidylat_synt, Thymidylate synthase	NA|202aa|up_8|NC_017803.1_7819935_7820541_-	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|85aa|up_7|NC_017803.1_7820609_7820864_-	cd07184, E_set_Isoamylase_like_N, N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins	NA|152aa|up_6|NC_017803.1_7820946_7821402_+	COG2153, ElaA, Predicted acyltransferase [General function prediction only]	NA|234aa|up_5|NC_017803.1_7821388_7822090_-	pfam06778, Chlor_dismutase, Chlorite dismutase	NA|465aa|up_4|NC_017803.1_7822086_7823481_-	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed	NA|373aa|up_3|NC_017803.1_7823546_7824665_-	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated	NA|191aa|up_2|NC_017803.1_7824663_7825236_+	pfam11452, DUF3000, Protein of unknown function (DUF3000)	NA|337aa|up_1|NC_017803.1_7825245_7826256_-	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|434aa|up_0|NC_017803.1_7826401_7827703_+	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis]	NA|399aa|down_0|NC_017803.1_7828089_7829286_+	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine	NA|688aa|down_1|NC_017803.1_7829282_7831346_+	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ	NA|303aa|down_2|NC_017803.1_7831445_7832354_+	pfam09770, PAT1, Topoisomerase II-associated protein PAT1	NA|411aa|down_3|NC_017803.1_7832350_7833583_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|221aa|down_4|NC_017803.1_7833579_7834242_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|570aa|down_5|NC_017803.1_7834703_7836413_+	NA	NA|450aa|down_6|NC_017803.1_7837455_7838805_-	pfam13360, PQQ_2, PQQ-like domain	NA|436aa|down_7|NC_017803.1_7838872_7840180_-	pfam13360, PQQ_2, PQQ-like domain	NA|641aa|down_8|NC_017803.1_7840228_7842151_-	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional	NA|468aa|down_9|NC_017803.1_7842300_7843704_+	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	19	7858276-7858381	18	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GATGTCGTGCGCTCCGGCCGATAA	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|255aa|up_5|NC_017803.1_7852966_7853731_-,NA|81aa|up_0|NC_017803.1_7857923_7858166_+,NA|91aa|down_9|NC_017803.1_7867261_7867534_-	NA|126aa|up_9|NC_017803.1_7850896_7851274_-	cd04488, RecG_wedge_OBF, RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG	NA|216aa|up_8|NC_017803.1_7851299_7851947_-	pfam12502, DUF3710, Protein of unknown function (DUF3710)	NA|159aa|up_7|NC_017803.1_7851933_7852410_-	PRK00601, dut, dUTP diphosphatase	NA|171aa|up_6|NC_017803.1_7852503_7853016_+	pfam11292, DUF3093, Protein of unknown function (DUF3093)	NA|255aa|up_5|NC_017803.1_7852966_7853731_-	NA	NA|99aa|up_4|NC_017803.1_7853856_7854153_-	pfam13834, DUF4193, Domain of unknown function (DUF4193)	NA|183aa|up_3|NC_017803.1_7854498_7855047_+	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator	NA|271aa|up_2|NC_017803.1_7855055_7855868_-	cd01639, IMPase, IMPase, inositol monophosphatase and related domains	NA|516aa|up_1|NC_017803.1_7856131_7857679_+	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|81aa|up_0|NC_017803.1_7857923_7858166_+	NA	NA|526aa|down_0|NC_017803.1_7858998_7860576_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|577aa|down_1|NC_017803.1_7860627_7862358_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|205aa|down_2|NC_017803.1_7862451_7863066_-	COG2860, COG2860, Predicted membrane protein [Function unknown]	NA|73aa|down_3|NC_017803.1_7863073_7863292_-	pfam11238, DUF3039, Protein of unknown function (DUF3039)	NA|317aa|down_4|NC_017803.1_7863415_7864366_+	pfam04227, Indigoidine_A, Indigoidine synthase A like protein	NA|296aa|down_5|NC_017803.1_7864551_7865439_+	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)	NA|124aa|down_6|NC_017803.1_7865666_7866038_-	pfam11298, DUF3099, Protein of unknown function (DUF3099)	NA|195aa|down_7|NC_017803.1_7866139_7866724_-	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein	NA|167aa|down_8|NC_017803.1_7866764_7867265_-	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms]	NA|91aa|down_9|NC_017803.1_7867261_7867534_-	NA
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	20	7917385-7917487	19	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	ACCGGCGGCTTCGGATGCCGGCGC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|241aa|up_8|NC_017803.1_7908320_7909043_-,NA|151aa|up_5|NC_017803.1_7911262_7911715_-,NA	NA|317aa|up_9|NC_017803.1_7907357_7908308_+	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|241aa|up_8|NC_017803.1_7908320_7909043_-	NA	NA|166aa|up_7|NC_017803.1_7909045_7909543_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|501aa|up_6|NC_017803.1_7909736_7911239_-	PRK14326, PRK14326, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional	NA|151aa|up_5|NC_017803.1_7911262_7911715_-	NA	NA|248aa|up_4|NC_017803.1_7911840_7912584_+	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|294aa|up_3|NC_017803.1_7912646_7913528_+	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold	NA|237aa|up_2|NC_017803.1_7913569_7914280_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|323aa|up_1|NC_017803.1_7914353_7915322_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|575aa|up_0|NC_017803.1_7915400_7917125_-	PRK12704, PRK12704, phosphodiesterase; Provisional	NA|213aa|down_0|NC_017803.1_7919045_7919684_-	PRK00117, recX, recombination regulator RecX; Reviewed	NA|349aa|down_1|NC_017803.1_7920265_7921312_-	PRK09354, recA, recombinase A; Provisional	NA|67aa|down_2|NC_017803.1_7921489_7921690_-	pfam11248, DUF3046, Protein of unknown function (DUF3046)	NA|222aa|down_3|NC_017803.1_7922168_7922834_-	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|449aa|down_4|NC_017803.1_7923299_7924646_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|414aa|down_5|NC_017803.1_7924709_7925951_+	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase	NA|218aa|down_6|NC_017803.1_7925973_7926627_+	PRK10958, PRK10958, leucine export protein LeuE; Provisional	NA|764aa|down_7|NC_017803.1_7926812_7929104_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|1656aa|down_8|NC_017803.1_7929239_7934207_+	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional	NA|309aa|down_9|NC_017803.1_7934402_7935329_-	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	21	7934033-7934274	1	PILER-CR	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCGGCGCCGCTGCGGGAGGCGCTGACCGCCGCCGGGTTCCGGGCTACGCCGCG	53	1	1	7934224-7934259	NC_017803.1_7934275-7934310	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA	NA|323aa|up_9|NC_017803.1_7914353_7915322_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|575aa|up_8|NC_017803.1_7915400_7917125_-	PRK12704, PRK12704, phosphodiesterase; Provisional	NA|213aa|up_7|NC_017803.1_7919045_7919684_-	PRK00117, recX, recombination regulator RecX; Reviewed	NA|349aa|up_6|NC_017803.1_7920265_7921312_-	PRK09354, recA, recombinase A; Provisional	NA|67aa|up_5|NC_017803.1_7921489_7921690_-	pfam11248, DUF3046, Protein of unknown function (DUF3046)	NA|222aa|up_4|NC_017803.1_7922168_7922834_-	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|449aa|up_3|NC_017803.1_7923299_7924646_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|414aa|up_2|NC_017803.1_7924709_7925951_+	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase	NA|218aa|up_1|NC_017803.1_7925973_7926627_+	PRK10958, PRK10958, leucine export protein LeuE; Provisional	NA|764aa|up_0|NC_017803.1_7926812_7929104_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|309aa|down_0|NC_017803.1_7934402_7935329_-	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family	NA|264aa|down_1|NC_017803.1_7935401_7936193_+	pfam01887, SAM_adeno_trans, S-adenosyl-l-methionine hydroxide adenosyltransferase	NA|288aa|down_2|NC_017803.1_7938156_7939020_-	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]	NA|133aa|down_3|NC_017803.1_7939507_7939906_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|162aa|down_4|NC_017803.1_7940067_7940553_-	pfam02464, CinA, Competence-damaged protein	NA|197aa|down_5|NC_017803.1_7940616_7941207_-	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA|487aa|down_6|NC_017803.1_7941203_7942664_-	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO	NA|220aa|down_7|NC_017803.1_7942752_7943412_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|158aa|down_8|NC_017803.1_7943444_7943918_+	pfam11695, DUF3291, Domain of unknown function (DUF3291)	NA|830aa|down_9|NC_017803.1_7944039_7946529_-	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	22	8356997-8357061	20	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCACAACGCCGCGCGACGAAGCAC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|126aa|up_2|NC_017803.1_8354425_8354803_-,NA	NA|372aa|up_9|NC_017803.1_8347569_8348685_+	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed	NA|314aa|up_8|NC_017803.1_8349718_8350660_-	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family	NA|411aa|up_7|NC_017803.1_8351004_8352237_-	COG0281, SfcA, Malic enzyme [Energy production and conversion]	NA|87aa|up_6|NC_017803.1_8352375_8352636_-	cd06530, S26_SPase_I, The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3	NA|135aa|up_5|NC_017803.1_8352769_8353174_+	pfam09055, Sod_Ni, Nickel-containing superoxide dismutase	NA|136aa|up_4|NC_017803.1_8353269_8353677_+	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|235aa|up_3|NC_017803.1_8353682_8354387_-	COG2186, FadR, Transcriptional regulators [Transcription]	NA|126aa|up_2|NC_017803.1_8354425_8354803_-	NA	NA|317aa|up_1|NC_017803.1_8354872_8355823_+	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]	NA|85aa|up_0|NC_017803.1_8356234_8356489_+	pfam02467, Whib, Transcription factor WhiB	NA|303aa|down_0|NC_017803.1_8357127_8358036_-	cd03416, CbiX_SirB_N, Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain	NA|255aa|down_1|NC_017803.1_8358017_8358782_-	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|564aa|down_2|NC_017803.1_8358933_8360625_-	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]	NA|513aa|down_3|NC_017803.1_8361170_8362709_-	pfam12282, H_kinase_N, Signal transduction histidine kinase	NA|339aa|down_4|NC_017803.1_8362738_8363755_-	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]	NA|524aa|down_5|NC_017803.1_8363886_8365458_+	sd00006, TPR, Tetratricopeptide repeat	NA|72aa|down_6|NC_017803.1_8365459_8365675_-	PRK14040, PRK14040, oxaloacetate decarboxylase subunit alpha	NA|95aa|down_7|NC_017803.1_8366070_8366355_-	TIGR03988, antisig_RsrA, mycothiol system anti-sigma-R factor	NA|200aa|down_8|NC_017803.1_8366359_8366959_-	TIGR02947, putative_RNA_polymerase_sigma_factor, RNA polymerase sigma-70 factor, TIGR02947 family	NA|205aa|down_9|NC_017803.1_8367212_8367827_-	COG3571, COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	23	8786794-8786974	21	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCCGCCTCACCACCGCACACCGC	23	1	1	8786883-8786899	NC_017803.1_3190060-3190076	NA	3	3	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|337aa|up_8|NC_017803.1_8777410_8778421_+,NA|148aa|down_4|NC_017803.1_8792697_8793141_+	NA|239aa|up_9|NC_017803.1_8776426_8777143_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|337aa|up_8|NC_017803.1_8777410_8778421_+	NA	NA|276aa|up_7|NC_017803.1_8778455_8779283_+	pfam11209, DUF2993, Protein of unknown function (DUF2993)	NA|283aa|up_6|NC_017803.1_8779606_8780455_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|112aa|up_5|NC_017803.1_8780460_8780796_+	pfam07210, DUF1416, Protein of unknown function (DUF1416)	NA|216aa|up_4|NC_017803.1_8781100_8781748_-	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown]	NA|374aa|up_3|NC_017803.1_8781793_8782915_+	COG4129, COG4129, Predicted membrane protein [Function unknown]	NA|550aa|up_2|NC_017803.1_8783266_8784916_+	pfam13367, PrsW-protease, Protease prsW family	NA|114aa|up_1|NC_017803.1_8784906_8785248_-	smart00883, Cpn10, Chaperonin 10 Kd subunit	NA|448aa|up_0|NC_017803.1_8785307_8786651_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|96aa|down_0|NC_017803.1_8787264_8787552_-	pfam13223, DUF4031, Protein of unknown function (DUF4031)	NA|157aa|down_1|NC_017803.1_8789605_8790076_-	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of  thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides	NA|541aa|down_2|NC_017803.1_8790182_8791805_-	PRK00013, groEL, chaperonin GroEL; Reviewed	NA|169aa|down_3|NC_017803.1_8792191_8792698_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|148aa|down_4|NC_017803.1_8792697_8793141_+	NA	NA|428aa|down_5|NC_017803.1_8793357_8794641_-	PRK07591, PRK07591, threonine synthase; Validated	NA|292aa|down_6|NC_017803.1_8794993_8795869_-	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein	NA|902aa|down_7|NC_017803.1_8795865_8798571_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|720aa|down_8|NC_017803.1_8798701_8800861_+	TIGR01243, Cell_division_cycle_protein_48_homolog_MJ1156, AAA family ATPase, CDC48 subfamily	NA|95aa|down_9|NC_017803.1_8800863_8801148_-	pfam11662, DUF3263, Protein of unknown function (DUF3263)
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	24	9194569-9194640	22	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTTGTTGCCACCACCGTTGTTGTT	24	1	1	9194593-9194616	NC_017803.1_9194626-9194649	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|253aa|down_8|NC_017803.1_9206122_9206881_-	NA|478aa|up_9|NC_017803.1_9177953_9179387_-	TIGR00665, DnaB, replicative DNA helicase	NA|756aa|up_8|NC_017803.1_9179796_9182064_+	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|830aa|up_7|NC_017803.1_9181969_9184459_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|150aa|up_6|NC_017803.1_9185274_9185724_-	PRK00137, rplI, 50S ribosomal protein L9; Reviewed	NA|80aa|up_5|NC_017803.1_9185738_9185978_-	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed	NA|191aa|up_4|NC_017803.1_9186046_9186619_-	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional	NA|97aa|up_3|NC_017803.1_9186684_9186975_-	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed	NA|322aa|up_2|NC_017803.1_9187271_9188237_-	PRK12373, PRK12373, NADH-quinone oxidoreductase subunit E	NA|258aa|up_1|NC_017803.1_9188367_9189141_+	PRK01060, PRK01060, endonuclease IV; Provisional	NA|506aa|up_0|NC_017803.1_9192839_9194357_-	COG5650, COG5650, Predicted integral membrane protein [Function unknown]	NA|145aa|down_0|NC_017803.1_9197371_9197806_-	pfam17249, DUF5318, Family of unknown function (DUF5318)	NA|218aa|down_1|NC_017803.1_9197967_9198621_+	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|360aa|down_2|NC_017803.1_9198644_9199724_+	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type	NA|381aa|down_3|NC_017803.1_9199869_9201012_+	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap	NA|734aa|down_4|NC_017803.1_9201091_9203293_+	cd06225, HAMP, Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain	NA|425aa|down_5|NC_017803.1_9203295_9204570_+	TIGR04012, poly_gGlu_PgsB, poly-gamma-glutamate synthase PgsB/CapB	NA|162aa|down_6|NC_017803.1_9204566_9205052_+	pfam14102, Caps_synth_CapC, Capsule biosynthesis CapC	NA|348aa|down_7|NC_017803.1_9205062_9206106_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|253aa|down_8|NC_017803.1_9206122_9206881_-	NA	NA|152aa|down_9|NC_017803.1_9207094_9207550_-	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]
GCF_000237145.1_ASM23714v1	NC_017803	Actinoplanes sp. SE50/110, complete genome	25	9229666-9229750	23	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CGATCCCGCGTCCGACCCGACCC	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|406aa|up_6|NC_017803.1_9220576_9221794_+,NA|217aa|up_2|NC_017803.1_9224466_9225117_-,NA	NA|559aa|up_9|NC_017803.1_9216243_9217920_+	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins	NA|518aa|up_8|NC_017803.1_9218141_9219695_+	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN	NA|236aa|up_7|NC_017803.1_9219872_9220580_+	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed	NA|406aa|up_6|NC_017803.1_9220576_9221794_+	NA	NA|320aa|up_5|NC_017803.1_9221898_9222858_+	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase	NA|106aa|up_4|NC_017803.1_9222874_9223192_+	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin	NA|384aa|up_3|NC_017803.1_9223314_9224466_+	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3	NA|217aa|up_2|NC_017803.1_9224466_9225117_-	NA	NA|437aa|up_1|NC_017803.1_9225311_9226622_+	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|321aa|up_0|NC_017803.1_9226618_9227581_+	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed	NA|211aa|down_0|NC_017803.1_9231805_9232438_-	TIGR00997, Probable_intracellular_septation_protein_A, intracellular septation protein A	NA|354aa|down_1|NC_017803.1_9232724_9233786_-	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein	NA|278aa|down_2|NC_017803.1_9233782_9234616_-	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]	NA|296aa|down_3|NC_017803.1_9235219_9236107_-	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA|196aa|down_4|NC_017803.1_9236108_9236696_-	COG1847, Jag, Predicted RNA-binding protein [General function prediction only]	NA|341aa|down_5|NC_017803.1_9236840_9237863_-	PRK01315, PRK01315, putative inner membrane protein translocase component YidC; Provisional	NA|86aa|down_6|NC_017803.1_9237864_9238122_-	pfam01809, Haemolytic, Haemolytic domain	NA|119aa|down_7|NC_017803.1_9238118_9238475_-	PRK03459, rnpA, ribonuclease P; Reviewed	NA|46aa|down_8|NC_017803.1_9238511_9238649_-	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed	NA|NA	NA
