assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	1	334937-335048	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGTTGCCGATCA	25	1	5	335007-335023|335007-335023|335007-335023|335007-335023|335007-335023	NZ_CP010339.1_844218-844202|NZ_CP010339.1_1191817-1191833|NZ_CP010339.1_1215725-1215709|NZ_CP010339.1_2425351-2425367|NZ_CP010339.1_4024443-4024459	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|159aa|down_0|NZ_CP010339.1_339551_340028_-	NA|86aa|up_9|NZ_CP010339.1_322889_323147_-	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|398aa|up_8|NZ_CP010339.1_323463_324657_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_7|NZ_CP010339.1_324692_326375_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_6|NZ_CP010339.1_326391_328587_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_5|NZ_CP010339.1_328700_329834_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_4|NZ_CP010339.1_329830_330451_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_3|NZ_CP010339.1_330547_331129_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_2|NZ_CP010339.1_331058_331784_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|290aa|up_1|NZ_CP010339.1_331917_332787_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_0|NZ_CP010339.1_332826_333255_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|159aa|down_0|NZ_CP010339.1_339551_340028_-	NA	NA|537aa|down_1|NZ_CP010339.1_342336_343947_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP010339.1_343970_344879_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|614aa|down_3|NZ_CP010339.1_345156_346998_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP010339.1_346994_348611_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|103aa|down_5|NZ_CP010339.1_352595_352904_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP010339.1_352906_354448_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP010339.1_354496_354790_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP010339.1_354819_355110_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP010339.1_355120_356008_+	pfam14011, ESX-1_EspG, EspG family
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	2	369434-370132	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	369722-369763|369797-369829	NZ_CP010339.1_377753-377794|NZ_CP010339.1_376568-376600	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP010339.1_366447_366750_+,NA|161aa|down_1|NZ_CP010339.1_379542_380025_-,NA|410aa|down_5|NZ_CP010339.1_382141_383371_+	NA|262aa|up_9|NZ_CP010339.1_361142_361928_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP010339.1_361916_362720_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP010339.1_362729_364127_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP010339.1_364305_366081_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP010339.1_366223_366451_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP010339.1_366447_366750_+	NA	NA|74aa|up_3|NZ_CP010339.1_366797_367019_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP010339.1_367015_367441_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP010339.1_367575_368208_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP010339.1_368204_369113_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP010339.1_378883_379555_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP010339.1_379542_380025_-	NA	NA|239aa|down_2|NZ_CP010339.1_380082_380799_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP010339.1_380900_381557_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP010339.1_381626_382118_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP010339.1_382141_383371_+	NA	NA|621aa|down_6|NZ_CP010339.1_383525_385388_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP010339.1_385459_385846_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|212aa|down_8|NZ_CP010339.1_385848_386484_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP010339.1_386571_387456_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	3	695066-695142	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP010339.1_680750_680966_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP010339.1_680962_681370_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP010339.1_681429_682116_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP010339.1_682269_684903_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP010339.1_684925_687313_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP010339.1_687450_688173_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP010339.1_688169_688967_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP010339.1_688968_689856_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP010339.1_689861_691076_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP010339.1_692099_693545_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP010339.1_696277_697828_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP010339.1_697879_698272_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP010339.1_698268_698526_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP010339.1_698708_699944_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP010339.1_700194_700608_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP010339.1_700604_700841_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP010339.1_700944_701451_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|177aa|down_7|NZ_CP010339.1_701564_702095_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP010339.1_702078_702840_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP010339.1_702896_703208_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	4	1193543-1193651	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP010339.1_1182910_1184542_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP010339.1_1184617_1185682_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP010339.1_1185734_1186208_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP010339.1_1186241_1187105_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP010339.1_1187109_1187967_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP010339.1_1187967_1189050_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP010339.1_1189130_1189550_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP010339.1_1189661_1190228_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP010339.1_1190224_1190620_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP010339.1_1190647_1192651_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP010339.1_1194928_1196692_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP010339.1_1196688_1197462_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP010339.1_1197473_1198511_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP010339.1_1198697_1199534_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP010339.1_1199649_1200501_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP010339.1_1200574_1201792_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP010339.1_1201844_1202789_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NZ_CP010339.1_1203185_1204079_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP010339.1_1204135_1205530_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|389aa|down_9|NZ_CP010339.1_1206483_1207650_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	5	1574087-1574797	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1574287-1574308	NZ_CP010339.1_1214479-1214458	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP010339.1_1565850_1566168_+,NA	NA|103aa|up_9|NZ_CP010339.1_1563365_1563674_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP010339.1_1563670_1565290_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP010339.1_1565850_1566168_+	NA	NA|209aa|up_6|NZ_CP010339.1_1566302_1566929_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP010339.1_1566994_1567327_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP010339.1_1567342_1568599_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP010339.1_1568726_1569938_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP010339.1_1570010_1571489_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP010339.1_1571485_1572871_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP010339.1_1572948_1573983_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP010339.1_1576012_1576414_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP010339.1_1576410_1576668_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP010339.1_1576750_1577710_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP010339.1_1577734_1578697_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|246aa|down_4|NZ_CP010339.1_1578695_1579433_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP010339.1_1579513_1581481_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP010339.1_1581498_1582323_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP010339.1_1582491_1582974_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP010339.1_1583045_1583870_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP010339.1_1584066_1585005_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	6	1574893-1575158	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	4	4	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP010339.1_1565850_1566168_+,NA	NA|103aa|up_9|NZ_CP010339.1_1563365_1563674_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP010339.1_1563670_1565290_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP010339.1_1565850_1566168_+	NA	NA|209aa|up_6|NZ_CP010339.1_1566302_1566929_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP010339.1_1566994_1567327_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP010339.1_1567342_1568599_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP010339.1_1568726_1569938_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP010339.1_1570010_1571489_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP010339.1_1571485_1572871_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP010339.1_1572948_1573983_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP010339.1_1576012_1576414_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP010339.1_1576410_1576668_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP010339.1_1576750_1577710_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP010339.1_1577734_1578697_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|246aa|down_4|NZ_CP010339.1_1578695_1579433_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP010339.1_1579513_1581481_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP010339.1_1581498_1582323_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP010339.1_1582491_1582974_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP010339.1_1583045_1583870_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP010339.1_1584066_1585005_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	7	2086190-2086444	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2086271-2086288|2086271-2086288|2086361-2086378	NZ_CP010339.1_404049-404032|NZ_CP010339.1_610438-610421|NZ_CP010339.1_3448658-3448641	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP010339.1_2085549_2085813_-,NA	NA|165aa|up_9|NZ_CP010339.1_2072011_2072506_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|211aa|up_8|NZ_CP010339.1_2072786_2073419_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP010339.1_2073777_2076603_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP010339.1_2076829_2077690_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP010339.1_2077730_2078597_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP010339.1_2078601_2080488_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP010339.1_2080503_2082537_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP010339.1_2082656_2084882_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP010339.1_2085157_2085553_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP010339.1_2085549_2085813_-	NA	NA|346aa|down_0|NZ_CP010339.1_2087581_2088619_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP010339.1_2088618_2089986_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|480aa|down_2|NZ_CP010339.1_2090159_2091599_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP010339.1_2091631_2093083_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP010339.1_2093112_2094063_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP010339.1_2094077_2094494_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP010339.1_2094771_2095194_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP010339.1_2095242_2095545_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP010339.1_2095541_2095856_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP010339.1_2095855_2097589_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	8	2166893-2167112	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|157aa|up_9|NZ_CP010339.1_2150434_2150905_-,NA|136aa|up_2|NZ_CP010339.1_2157929_2158337_-,NA|127aa|down_5|NZ_CP010339.1_2174628_2175009_-	NA|157aa|up_9|NZ_CP010339.1_2150434_2150905_-	NA	NA|155aa|up_8|NZ_CP010339.1_2151244_2151709_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_7|NZ_CP010339.1_2151898_2154121_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_6|NZ_CP010339.1_2154158_2154602_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_5|NZ_CP010339.1_2154715_2155309_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_4|NZ_CP010339.1_2155391_2155997_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_3|NZ_CP010339.1_2156096_2157101_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|136aa|up_2|NZ_CP010339.1_2157929_2158337_-	NA	NA|767aa|up_1|NZ_CP010339.1_2158471_2160772_+	PLN02892, PLN02892, isocitrate lyase	NA|1483aa|up_0|NZ_CP010339.1_2160941_2165390_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP010339.1_2169139_2169604_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP010339.1_2169701_2170565_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP010339.1_2170602_2171874_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP010339.1_2172145_2173261_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP010339.1_2173251_2174592_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP010339.1_2174628_2175009_-	NA	NA|621aa|down_6|NZ_CP010339.1_2175165_2177028_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP010339.1_2177035_2177515_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP010339.1_2177751_2178525_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|215aa|down_9|NZ_CP010339.1_2179332_2179977_-	TIGR03085, TIGR03085, TIGR03085 family protein
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	9	3117294-3118429	2,7,2	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-B,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGA,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	35,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	14,14,15	15	TypeIII-A,TypeIII-B,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_7|NZ_CP010339.1_3110573_3110828_-,NA|135aa|up_6|NZ_CP010339.1_3110975_3111380_+,NA|64aa|up_5|NZ_CP010339.1_3111376_3111568_+,NA|86aa|up_4|NZ_CP010339.1_3113154_3113412_+,NA|104aa|up_3|NZ_CP010339.1_3113516_3113828_+,NA|203aa|up_2|NZ_CP010339.1_3114247_3114856_+,NA	NA|348aa|up_9|NZ_CP010339.1_3108888_3109932_-	COG5586, COG5586, Uncharacterized conserved protein [Function unknown]	NA|92aa|up_8|NZ_CP010339.1_3110122_3110398_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_7|NZ_CP010339.1_3110573_3110828_-	NA	NA|135aa|up_6|NZ_CP010339.1_3110975_3111380_+	NA	NA|64aa|up_5|NZ_CP010339.1_3111376_3111568_+	NA	NA|86aa|up_4|NZ_CP010339.1_3113154_3113412_+	NA	NA|104aa|up_3|NZ_CP010339.1_3113516_3113828_+	NA	NA|203aa|up_2|NZ_CP010339.1_3114247_3114856_+	NA	NA|470aa|up_1|NZ_CP010339.1_3114926_3116336_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP010339.1_3116332_3117145_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP010339.1_3118455_3119717_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP010339.1_3121667_3122009_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP010339.1_3122009_3123026_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|416aa|down_3|NZ_CP010339.1_3123038_3124286_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP010339.1_3124282_3125410_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP010339.1_3125406_3126315_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP010339.1_3126295_3127006_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP010339.1_3127015_3127390_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP010339.1_3127386_3129825_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|263aa|down_9|NZ_CP010339.1_3129821_3130610_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	10	3119752-3121619	8,3,3	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-B,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	25,25,24	25	TypeIII-A,TypeIII-B,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP010339.1_3110573_3110828_-,NA|135aa|up_7|NZ_CP010339.1_3110975_3111380_+,NA|64aa|up_6|NZ_CP010339.1_3111376_3111568_+,NA|86aa|up_5|NZ_CP010339.1_3113154_3113412_+,NA|104aa|up_4|NZ_CP010339.1_3113516_3113828_+,NA|203aa|up_3|NZ_CP010339.1_3114247_3114856_+,NA	NA|92aa|up_9|NZ_CP010339.1_3110122_3110398_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP010339.1_3110573_3110828_-	NA	NA|135aa|up_7|NZ_CP010339.1_3110975_3111380_+	NA	NA|64aa|up_6|NZ_CP010339.1_3111376_3111568_+	NA	NA|86aa|up_5|NZ_CP010339.1_3113154_3113412_+	NA	NA|104aa|up_4|NZ_CP010339.1_3113516_3113828_+	NA	NA|203aa|up_3|NZ_CP010339.1_3114247_3114856_+	NA	NA|470aa|up_2|NZ_CP010339.1_3114926_3116336_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP010339.1_3116332_3117145_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP010339.1_3118455_3119717_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP010339.1_3121667_3122009_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP010339.1_3122009_3123026_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|416aa|down_2|NZ_CP010339.1_3123038_3124286_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP010339.1_3124282_3125410_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP010339.1_3125406_3126315_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP010339.1_3126295_3127006_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP010339.1_3127015_3127390_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP010339.1_3127386_3129825_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|263aa|down_8|NZ_CP010339.1_3129821_3130610_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP010339.1_3130943_3131489_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	11	3834928-3835017	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|77aa|up_6|NZ_CP010339.1_3828323_3828554_+,NA|121aa|up_5|NZ_CP010339.1_3828657_3829020_-,NA|121aa|down_0|NZ_CP010339.1_3836002_3836365_-,NA|52aa|down_2|NZ_CP010339.1_3838206_3838362_-,NA|52aa|down_3|NZ_CP010339.1_3838386_3838542_-,NA|238aa|down_5|NZ_CP010339.1_3842576_3843290_-	NA|212aa|up_9|NZ_CP010339.1_3826002_3826638_-	COG1214, COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|169aa|up_8|NZ_CP010339.1_3826634_3827141_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|387aa|up_7|NZ_CP010339.1_3827137_3828298_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_6|NZ_CP010339.1_3828323_3828554_+	NA	NA|121aa|up_5|NZ_CP010339.1_3828657_3829020_-	NA	NA|177aa|up_4|NZ_CP010339.1_3829182_3829713_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|177aa|up_3|NZ_CP010339.1_3829979_3830510_+	pfam00823, PPE, PPE family	NA|252aa|up_2|NZ_CP010339.1_3830827_3831583_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|100aa|up_1|NZ_CP010339.1_3833706_3834006_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_CP010339.1_3834091_3834634_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP010339.1_3836002_3836365_-	NA	NA|179aa|down_1|NZ_CP010339.1_3836527_3837064_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP010339.1_3838206_3838362_-	NA	NA|52aa|down_3|NZ_CP010339.1_3838386_3838542_-	NA	NA|461aa|down_4|NZ_CP010339.1_3839734_3841117_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|238aa|down_5|NZ_CP010339.1_3842576_3843290_-	NA	NA|285aa|down_6|NZ_CP010339.1_3843300_3844155_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_7|NZ_CP010339.1_3844376_3846251_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_8|NZ_CP010339.1_3846272_3846749_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)	NA|281aa|down_9|NZ_CP010339.1_3846758_3847601_+	pfam12740, Chlorophyllase2, Chlorophyllase enzyme
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	12	3918660-3919601	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGNNNCGGCGGCNCCGGCGGC	24	0	0	NA	NA	NA	12	12	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP010339.1_3940914_3941754_+	NA|358aa|up_9|NZ_CP010339.1_3903837_3904911_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|351aa|up_8|NZ_CP010339.1_3904900_3905953_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_7|NZ_CP010339.1_3905952_3907155_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_6|NZ_CP010339.1_3907174_3908017_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_5|NZ_CP010339.1_3908051_3908816_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_4|NZ_CP010339.1_3909041_3909995_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_3|NZ_CP010339.1_3910019_3910211_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_2|NZ_CP010339.1_3910425_3911628_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_1|NZ_CP010339.1_3911652_3912774_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_0|NZ_CP010339.1_3912844_3914353_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP010339.1_3938307_3939954_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP010339.1_3940027_3940819_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP010339.1_3940914_3941754_+	NA	NA|399aa|down_3|NZ_CP010339.1_3941808_3943005_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP010339.1_3943033_3943744_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|344aa|down_5|NZ_CP010339.1_3943808_3944840_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|335aa|down_6|NZ_CP010339.1_3944911_3945916_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP010339.1_3945931_3946996_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP010339.1_3947012_3948197_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP010339.1_3948238_3949270_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	13	3935835-3937600	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGNNNCGGCGGCNNNGGCGGNNNCGGCGGC	37	2	9	3936434-3936468|3936434-3936468|3936434-3936468|3936434-3936468|3936434-3936468|3937331-3937356|3937331-3937356|3937331-3937356|3937331-3937356	NZ_CP010339.1_3934465-3934499|NZ_CP010339.1_3934842-3934876|NZ_CP010339.1_3935192-3935226|NZ_CP010339.1_3935543-3935577|NZ_CP010339.1_3935827-3935861|NZ_CP010339.1_3928292-3928317|NZ_CP010339.1_3928627-3928652|NZ_CP010339.1_3928970-3928995|NZ_CP010339.1_3929315-3929340	NA	22	22	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP010339.1_3940914_3941754_+	NA|358aa|up_9|NZ_CP010339.1_3903837_3904911_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|351aa|up_8|NZ_CP010339.1_3904900_3905953_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_7|NZ_CP010339.1_3905952_3907155_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_6|NZ_CP010339.1_3907174_3908017_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_5|NZ_CP010339.1_3908051_3908816_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_4|NZ_CP010339.1_3909041_3909995_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_3|NZ_CP010339.1_3910019_3910211_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_2|NZ_CP010339.1_3910425_3911628_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_1|NZ_CP010339.1_3911652_3912774_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_0|NZ_CP010339.1_3912844_3914353_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP010339.1_3938307_3939954_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP010339.1_3940027_3940819_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP010339.1_3940914_3941754_+	NA	NA|399aa|down_3|NZ_CP010339.1_3941808_3943005_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP010339.1_3943033_3943744_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|344aa|down_5|NZ_CP010339.1_3943808_3944840_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|335aa|down_6|NZ_CP010339.1_3944911_3945916_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP010339.1_3945931_3946996_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP010339.1_3947012_3948197_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP010339.1_3948238_3949270_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_001545015.1_ASM154501v1	NZ_CP010339	Mycobacterium tuberculosis strain 22103 chromosome, complete genome	14	4098485-4098573	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_6|NZ_CP010339.1_4089071_4089842_-,NA|233aa|up_0|NZ_CP010339.1_4097589_4098288_-,NA|126aa|down_6|NZ_CP010339.1_4103808_4104186_+	NA|267aa|up_9|NZ_CP010339.1_4083946_4084747_-	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion]	NA|388aa|up_8|NZ_CP010339.1_4084743_4085907_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|288aa|up_7|NZ_CP010339.1_4087453_4088317_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_6|NZ_CP010339.1_4089071_4089842_-	NA	NA|549aa|up_5|NZ_CP010339.1_4089838_4091485_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_4|NZ_CP010339.1_4091481_4092345_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_3|NZ_CP010339.1_4092337_4093264_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_2|NZ_CP010339.1_4093265_4094891_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|652aa|up_1|NZ_CP010339.1_4095598_4097554_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP010339.1_4097589_4098288_-	NA	NA|173aa|down_0|NZ_CP010339.1_4098633_4099152_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP010339.1_4099152_4100136_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP010339.1_4100128_4101322_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP010339.1_4101327_4102149_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|216aa|down_4|NZ_CP010339.1_4102280_4102928_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP010339.1_4102963_4103701_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP010339.1_4103808_4104186_+	NA	NA|225aa|down_7|NZ_CP010339.1_4104284_4104959_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP010339.1_4105064_4105859_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP010339.1_4105865_4106321_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
