assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	1	333372-334170	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGNGCCGCCGGNN	18	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP018303.1_332887_333070_-,NA	NA|398aa|up_9|NZ_CP018303.1_323065_324259_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP018303.1_324294_325977_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP018303.1_325993_328189_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP018303.1_328302_329436_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP018303.1_329432_330053_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP018303.1_330149_330731_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP018303.1_330660_331386_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP018303.1_331475_332396_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP018303.1_332435_332864_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP018303.1_332887_333070_-	NA	NA|838aa|down_0|NZ_CP018303.1_336269_338783_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP018303.1_339073_340684_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP018303.1_340707_341616_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP018303.1_341839_343735_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP018303.1_343731_345348_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP018303.1_345344_349337_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP018303.1_349333_349642_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP018303.1_349644_351186_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP018303.1_351234_351528_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP018303.1_351557_351848_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	2	337814-338036	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP018303.1_332887_333070_-,NA	NA|561aa|up_9|NZ_CP018303.1_324294_325977_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP018303.1_325993_328189_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP018303.1_328302_329436_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP018303.1_329432_330053_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP018303.1_330149_330731_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP018303.1_330660_331386_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP018303.1_331475_332396_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP018303.1_332435_332864_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP018303.1_332887_333070_-	NA	NA|615aa|up_0|NZ_CP018303.1_333164_335009_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|537aa|down_0|NZ_CP018303.1_339073_340684_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP018303.1_340707_341616_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP018303.1_341839_343735_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP018303.1_343731_345348_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP018303.1_345344_349337_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP018303.1_349333_349642_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP018303.1_349644_351186_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP018303.1_351234_351528_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP018303.1_351557_351848_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP018303.1_351858_352746_+	pfam14011, ESX-1_EspG, EspG family
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	3	366172-366870	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366460-366501|366535-366567	NZ_CP018303.1_374506-374547|NZ_CP018303.1_373321-373353	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP018303.1_363185_363488_+,NA|161aa|down_1|NZ_CP018303.1_376295_376778_-,NA|410aa|down_5|NZ_CP018303.1_378894_380124_+	NA|262aa|up_9|NZ_CP018303.1_357880_358666_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP018303.1_358654_359458_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP018303.1_359467_360865_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP018303.1_361043_362819_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP018303.1_362961_363189_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP018303.1_363185_363488_+	NA	NA|74aa|up_3|NZ_CP018303.1_363535_363757_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP018303.1_363753_364179_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP018303.1_364313_364946_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP018303.1_364942_365851_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP018303.1_375636_376308_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP018303.1_376295_376778_-	NA	NA|239aa|down_2|NZ_CP018303.1_376835_377552_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP018303.1_377653_378310_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP018303.1_378379_378871_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP018303.1_378894_380124_+	NA	NA|621aa|down_6|NZ_CP018303.1_380278_382141_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP018303.1_382212_382599_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP018303.1_382601_383264_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP018303.1_383324_384209_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	4	577510-577627	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GATGACCTGCGCCGACGACGATGCAGAGCGTAGCGATGAGG	41	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|110aa|down_2|NZ_CP018303.1_580206_580536_-,NA|330aa|down_3|NZ_CP018303.1_580532_581522_-,NA|297aa|down_5|NZ_CP018303.1_582255_583146_-,NA|311aa|down_7|NZ_CP018303.1_584208_585141_+	NA|281aa|up_9|NZ_CP018303.1_566008_566851_-	cd07581, nitrilase_3, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases)	NA|175aa|up_8|NZ_CP018303.1_566920_567445_-	pfam10698, DUF2505, Protein of unknown function (DUF2505)	NA|370aa|up_7|NZ_CP018303.1_567471_568581_+	PRK13903, murB, UDP-N-acetylmuramate dehydrogenase	NA|452aa|up_6|NZ_CP018303.1_568642_569998_+	pfam17964, Big_10, Bacterial Ig domain	NA|252aa|up_5|NZ_CP018303.1_569978_570734_-	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]	NA|439aa|up_4|NZ_CP018303.1_570916_572233_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|481aa|up_3|NZ_CP018303.1_572280_573723_+	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase	NA|184aa|up_2|NZ_CP018303.1_573719_574271_+	pfam10722, YbjN, Putative bacterial sensory transduction regulator	NA|202aa|up_1|NZ_CP018303.1_574596_575202_+	TIGR00948, Hypothetical_protein_Rv0488/MT0507/Mb0498	NA|250aa|up_0|NZ_CP018303.1_575358_576108_+	PRK14120, gpmA, phosphoglyceromutase; Provisional	NA|228aa|down_0|NZ_CP018303.1_577640_578324_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|630aa|down_1|NZ_CP018303.1_578320_580210_-	pfam00732, GMC_oxred_N, GMC oxidoreductase	NA|110aa|down_2|NZ_CP018303.1_580206_580536_-	NA	NA|330aa|down_3|NZ_CP018303.1_580532_581522_-	NA	NA|243aa|down_4|NZ_CP018303.1_581526_582255_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|297aa|down_5|NZ_CP018303.1_582255_583146_-	NA	NA|329aa|down_6|NZ_CP018303.1_583225_584212_+	pfam02541, Ppx-GppA, Ppx/GppA phosphatase family	NA|311aa|down_7|NZ_CP018303.1_584208_585141_+	NA	NA|281aa|down_8|NZ_CP018303.1_585156_585999_+	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|292aa|down_9|NZ_CP018303.1_586014_586890_+	pfam13622, 4HBT_3, Thioesterase-like superfamily
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	5	628198-628335	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	628216-628233|628216-628233|628300-628317	NZ_CP018303.1_22466-22483|NZ_CP018303.1_1408868-1408885|NZ_CP018303.1_970680-970697	NA	3	3	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NZ_CP018303.1_618952_619114_-,NA|478aa|up_0|NZ_CP018303.1_625213_626647_-,NA|450aa|down_2|NZ_CP018303.1_629970_631320_-,NA|93aa|down_5|NZ_CP018303.1_632850_633129_-	NA|325aa|up_9|NZ_CP018303.1_616722_617697_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP018303.1_617738_618956_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP018303.1_618952_619114_-	NA	NA|106aa|up_6|NZ_CP018303.1_619160_619478_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|623aa|up_5|NZ_CP018303.1_619624_621493_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP018303.1_621388_622396_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP018303.1_622477_623356_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP018303.1_623372_624167_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP018303.1_624163_625204_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP018303.1_625213_626647_-	NA	NA|211aa|down_0|NZ_CP018303.1_628658_629291_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP018303.1_629287_629950_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP018303.1_629970_631320_-	NA	NA|381aa|down_3|NZ_CP018303.1_631331_632474_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP018303.1_632488_632791_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP018303.1_632850_633129_-	NA	NA|418aa|down_6|NZ_CP018303.1_633125_634379_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP018303.1_634498_634885_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP018303.1_634947_635832_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP018303.1_635927_636830_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	6	688932-689008	3	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP018303.1_674616_674832_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP018303.1_674828_675236_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP018303.1_675295_675982_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP018303.1_676135_678769_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP018303.1_678791_681179_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP018303.1_681316_682039_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP018303.1_682035_682833_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP018303.1_682834_683722_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP018303.1_683727_684942_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP018303.1_685965_687411_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP018303.1_690143_691694_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP018303.1_691745_692138_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP018303.1_692134_692392_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP018303.1_692574_693810_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP018303.1_694060_694474_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP018303.1_694470_694707_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP018303.1_694810_695317_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP018303.1_695430_695901_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP018303.1_695944_696706_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP018303.1_696762_697074_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	7	922693-923640	3	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	923476-923511|923476-923511|923476-923511	NZ_CP018303.1_672035-672000|NZ_CP018303.1_1210641-1210676|NZ_CP018303.1_2412874-2412839	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP018303.1_927650_928202_-,NA|81aa|down_9|NZ_CP018303.1_935023_935266_+	NA|390aa|up_9|NZ_CP018303.1_912558_913728_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_8|NZ_CP018303.1_913815_914832_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_7|NZ_CP018303.1_914993_915635_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_6|NZ_CP018303.1_915715_916771_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_5|NZ_CP018303.1_916822_917215_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_4|NZ_CP018303.1_917272_917695_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_3|NZ_CP018303.1_917656_917947_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_2|NZ_CP018303.1_918051_918957_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_1|NZ_CP018303.1_918975_919791_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|138aa|up_0|NZ_CP018303.1_921032_921446_+	pfam00934, PE, PE family	NA|883aa|down_0|NZ_CP018303.1_923909_926558_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP018303.1_927025_927670_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP018303.1_927650_928202_-	NA	NA|421aa|down_3|NZ_CP018303.1_928319_929581_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|218aa|down_4|NZ_CP018303.1_929709_930363_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_5|NZ_CP018303.1_930433_931462_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_6|NZ_CP018303.1_932150_932921_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_7|NZ_CP018303.1_933007_933820_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_8|NZ_CP018303.1_933887_934748_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_9|NZ_CP018303.1_935023_935266_+	NA
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	8	1208824-1209653	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	3	75	1209207-1209231|1209207-1209231|1209207-1209231|1209207-1209231|1209207-1209231|1209363-1209384|1209363-1209384|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498|1209480-1209498	NZ_CP018303.1_334344-334320|NZ_CP018303.1_334407-334383|NZ_CP018303.1_1570015-1569991|NZ_CP018303.1_3908874-3908898|NZ_CP018303.1_3922420-3922444|NZ_CP018303.1_834873-834894|NZ_CP018303.1_1214536-1214557|NZ_CP018303.1_671699-671681|NZ_CP018303.1_1210323-1210341|NZ_CP018303.1_1214509-1214527|NZ_CP018303.1_1214581-1214599|NZ_CP018303.1_1627350-1627332|NZ_CP018303.1_1630203-1630185|NZ_CP018303.1_1977128-1977110|NZ_CP018303.1_2047408-2047390|NZ_CP018303.1_2047855-2047837|NZ_CP018303.1_2047954-2047936|NZ_CP018303.1_2786706-2786688|NZ_CP018303.1_2790234-2790216|NZ_CP018303.1_150105-150123|NZ_CP018303.1_334929-334911|NZ_CP018303.1_335382-335364|NZ_CP018303.1_335433-335415|NZ_CP018303.1_335442-335424|NZ_CP018303.1_337713-337695|NZ_CP018303.1_338109-338091|NZ_CP018303.1_338138-338156|NZ_CP018303.1_338232-338214|NZ_CP018303.1_362763-362745|NZ_CP018303.1_443076-443058|NZ_CP018303.1_543814-543796|NZ_CP018303.1_620899-620917|NZ_CP018303.1_621121-621139|NZ_CP018303.1_670865-670847|NZ_CP018303.1_837656-837674|NZ_CP018303.1_1089778-1089796|NZ_CP018303.1_1090426-1090444|NZ_CP018303.1_1094496-1094478|NZ_CP018303.1_1209852-1209870|NZ_CP018303.1_1210242-1210260|NZ_CP018303.1_1210530-1210548|NZ_CP018303.1_1210548-1210566|NZ_CP018303.1_1214836-1214854|NZ_CP018303.1_1485898-1485880|NZ_CP018303.1_1615767-1615749|NZ_CP018303.1_1632923-1632905|NZ_CP018303.1_1632932-1632914|NZ_CP018303.1_1851952-1851934|NZ_CP018303.1_1852480-1852462|NZ_CP018303.1_1976402-1976384|NZ_CP018303.1_1987365-1987383|NZ_CP018303.1_2074622-2074604|NZ_CP018303.1_2294025-2294007|NZ_CP018303.1_2347547-2347529|NZ_CP018303.1_2408700-2408718|NZ_CP018303.1_2412787-2412769|NZ_CP018303.1_2556867-2556849|NZ_CP018303.1_2679431-2679449|NZ_CP018303.1_2780021-2780003|NZ_CP018303.1_2780603-2780585|NZ_CP018303.1_3037835-3037853|NZ_CP018303.1_3037934-3037952|NZ_CP018303.1_3686749-3686767|NZ_CP018303.1_3722853-3722835|NZ_CP018303.1_3723477-3723459|NZ_CP018303.1_3723720-3723702|NZ_CP018303.1_3723853-3723835|NZ_CP018303.1_3786277-3786295|NZ_CP018303.1_3786460-3786478|NZ_CP018303.1_3786628-3786646|NZ_CP018303.1_3907858-3907876|NZ_CP018303.1_3909588-3909606|NZ_CP018303.1_3916835-3916853|NZ_CP018303.1_4005361-4005343|NZ_CP018303.1_4068800-4068818	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP018303.1_1204256_1204523_+,NA|61aa|down_3|NZ_CP018303.1_1212116_1212299_+,NA|35aa|down_4|NZ_CP018303.1_1212408_1212513_+	NA|465aa|up_9|NZ_CP018303.1_1198590_1199985_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP018303.1_1200186_1200909_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP018303.1_1200940_1202107_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP018303.1_1202177_1202672_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP018303.1_1202857_1203292_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP018303.1_1203393_1204260_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP018303.1_1204256_1204523_+	NA	NA|674aa|up_2|NZ_CP018303.1_1204509_1206531_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP018303.1_1206629_1207358_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP018303.1_1207468_1208257_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP018303.1_1210931_1211252_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP018303.1_1211404_1211839_+	pfam00934, PE, PE family	NA|63aa|down_2|NZ_CP018303.1_1211916_1212105_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP018303.1_1212116_1212299_+	NA	NA|35aa|down_4|NZ_CP018303.1_1212408_1212513_+	NA	NA|152aa|down_5|NZ_CP018303.1_1212490_1212946_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|823aa|down_6|NZ_CP018303.1_1213360_1215829_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP018303.1_1216046_1216985_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP018303.1_1217372_1218653_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP018303.1_1218757_1219585_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	9	1568874-1569945	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP018303.1_1560637_1560955_+,NA	NA|103aa|up_9|NZ_CP018303.1_1558152_1558461_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP018303.1_1558457_1560077_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP018303.1_1560637_1560955_+	NA	NA|209aa|up_6|NZ_CP018303.1_1561089_1561716_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP018303.1_1561781_1562114_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP018303.1_1562129_1563386_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP018303.1_1563513_1564725_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP018303.1_1564797_1566276_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP018303.1_1566272_1567658_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP018303.1_1567735_1568770_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP018303.1_1570799_1571201_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP018303.1_1571197_1571455_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP018303.1_1571537_1572497_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP018303.1_1572521_1573484_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP018303.1_1573617_1574220_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP018303.1_1574300_1576268_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP018303.1_1576285_1577110_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP018303.1_1577278_1577761_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP018303.1_1577832_1578657_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP018303.1_1578853_1579792_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	10	1633501-1633727	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP018303.1_1619775_1619889_-,NA|137aa|up_7|NZ_CP018303.1_1619938_1620349_-,NA|288aa|down_2|NZ_CP018303.1_1637553_1638417_+	NA|162aa|up_9|NZ_CP018303.1_1618858_1619344_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP018303.1_1619775_1619889_-	NA	NA|137aa|up_7|NZ_CP018303.1_1619938_1620349_-	NA	NA|248aa|up_6|NZ_CP018303.1_1620365_1621109_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP018303.1_1621105_1622017_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP018303.1_1622069_1623614_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP018303.1_1623610_1624732_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP018303.1_1624748_1626851_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1408aa|up_1|NZ_CP018303.1_1627289_1631513_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP018303.1_1631914_1632841_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP018303.1_1635254_1636520_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP018303.1_1636547_1637534_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP018303.1_1637553_1638417_+	NA	NA|311aa|down_3|NZ_CP018303.1_1638366_1639299_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP018303.1_1639410_1640196_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP018303.1_1640192_1641134_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP018303.1_1641236_1643012_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP018303.1_1643059_1643866_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP018303.1_1643862_1646403_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP018303.1_1646399_1647593_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	11	2074094-2074348	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2074175-2074192|2074175-2074192|2074265-2074282	NZ_CP018303.1_400802-400785|NZ_CP018303.1_604270-604253|NZ_CP018303.1_3432839-3432822	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP018303.1_2073453_2073717_-,NA	NA|165aa|up_9|NZ_CP018303.1_2059803_2060298_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP018303.1_2060645_2061323_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP018303.1_2061681_2064507_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP018303.1_2064733_2065594_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP018303.1_2065634_2066501_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP018303.1_2066505_2068392_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP018303.1_2068407_2070441_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP018303.1_2070560_2072786_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP018303.1_2073061_2073457_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP018303.1_2073453_2073717_-	NA	NA|346aa|down_0|NZ_CP018303.1_2075485_2076523_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP018303.1_2076522_2077890_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP018303.1_2078063_2079500_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP018303.1_2079535_2080987_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP018303.1_2081016_2081967_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP018303.1_2081981_2082398_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP018303.1_2082675_2083098_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP018303.1_2083146_2083449_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP018303.1_2083445_2083760_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP018303.1_2083759_2085493_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	12	2154327-2154546	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP018303.1_2145790_2146198_-,NA|127aa|down_5|NZ_CP018303.1_2162062_2162443_-	NA|741aa|up_9|NZ_CP018303.1_2139758_2141981_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP018303.1_2142018_2142462_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP018303.1_2142575_2143169_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP018303.1_2143251_2143857_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP018303.1_2143956_2144961_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP018303.1_2145060_2145813_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP018303.1_2145790_2146198_-	NA	NA|368aa|up_2|NZ_CP018303.1_2146332_2147436_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP018303.1_2147435_2148632_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1341aa|up_0|NZ_CP018303.1_2148801_2152824_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP018303.1_2156573_2157038_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP018303.1_2157135_2157999_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP018303.1_2158036_2159308_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP018303.1_2159579_2160695_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP018303.1_2160685_2162026_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP018303.1_2162062_2162443_-	NA	NA|621aa|down_6|NZ_CP018303.1_2162599_2164462_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP018303.1_2164469_2164949_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP018303.1_2165185_2165959_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP018303.1_2165962_2166730_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	13	3102426-3103708	3,7,5	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-B,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	15,16,17	17	TypeIII-C,TypeIII-B,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP018303.1_3095705_3095960_-,NA|135aa|up_7|NZ_CP018303.1_3096107_3096512_+,NA|64aa|up_6|NZ_CP018303.1_3096508_3096700_+,NA|86aa|up_4|NZ_CP018303.1_3098286_3098544_+,NA|104aa|up_3|NZ_CP018303.1_3098648_3098960_+,NA|203aa|up_2|NZ_CP018303.1_3099379_3099988_+,NA	NA|92aa|up_9|NZ_CP018303.1_3095254_3095530_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP018303.1_3095705_3095960_-	NA	NA|135aa|up_7|NZ_CP018303.1_3096107_3096512_+	NA	NA|64aa|up_6|NZ_CP018303.1_3096508_3096700_+	NA	NA|385aa|up_5|NZ_CP018303.1_3096898_3098053_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP018303.1_3098286_3098544_+	NA	NA|104aa|up_3|NZ_CP018303.1_3098648_3098960_+	NA	NA|203aa|up_2|NZ_CP018303.1_3099379_3099988_+	NA	NA|470aa|up_1|NZ_CP018303.1_3100058_3101468_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP018303.1_3101464_3102277_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP018303.1_3103734_3104996_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP018303.1_3106576_3106918_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP018303.1_3106918_3107935_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP018303.1_3107947_3109096_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP018303.1_3109191_3110319_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP018303.1_3110315_3111224_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP018303.1_3111204_3111915_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP018303.1_3111924_3112299_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP018303.1_3112295_3114734_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NZ_CP018303.1_3114730_3115675_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	14	3105031-3106528	8,6,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-B,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	20,20,19	20	TypeIII-C,TypeIII-B,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP018303.1_3095705_3095960_-,NA|135aa|up_8|NZ_CP018303.1_3096107_3096512_+,NA|64aa|up_7|NZ_CP018303.1_3096508_3096700_+,NA|86aa|up_5|NZ_CP018303.1_3098286_3098544_+,NA|104aa|up_4|NZ_CP018303.1_3098648_3098960_+,NA|203aa|up_3|NZ_CP018303.1_3099379_3099988_+,NA	NA|85aa|up_9|NZ_CP018303.1_3095705_3095960_-	NA	NA|135aa|up_8|NZ_CP018303.1_3096107_3096512_+	NA	NA|64aa|up_7|NZ_CP018303.1_3096508_3096700_+	NA	NA|385aa|up_6|NZ_CP018303.1_3096898_3098053_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP018303.1_3098286_3098544_+	NA	NA|104aa|up_4|NZ_CP018303.1_3098648_3098960_+	NA	NA|203aa|up_3|NZ_CP018303.1_3099379_3099988_+	NA	NA|470aa|up_2|NZ_CP018303.1_3100058_3101468_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP018303.1_3101464_3102277_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP018303.1_3103734_3104996_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP018303.1_3106576_3106918_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP018303.1_3106918_3107935_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP018303.1_3107947_3109096_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP018303.1_3109191_3110319_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP018303.1_3110315_3111224_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP018303.1_3111204_3111915_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP018303.1_3111924_3112299_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP018303.1_3112295_3114734_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_8|NZ_CP018303.1_3114730_3115675_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP018303.1_3115852_3116398_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	15	3725879-3726726	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGNNNCCNCCGTNNCCGCC	23	0	0	NA	NA	NA	11	11	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP018303.1_3740599_3740887_-,NA|87aa|down_9|NZ_CP018303.1_3754007_3754268_-	NA|147aa|up_9|NZ_CP018303.1_3706576_3707017_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP018303.1_3707050_3707920_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP018303.1_3707940_3708951_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_6|NZ_CP018303.1_3709235_3709868_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP018303.1_3709934_3711164_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP018303.1_3711446_3712796_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP018303.1_3712807_3713947_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP018303.1_3713943_3714675_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2538aa|up_1|NZ_CP018303.1_3714683_3722297_-	pfam00823, PPE, PPE family	NA|339aa|up_0|NZ_CP018303.1_3722345_3723362_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_CP018303.1_3728469_3728727_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP018303.1_3728982_3738456_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP018303.1_3739081_3739528_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|273aa|down_3|NZ_CP018303.1_3739564_3740383_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP018303.1_3740599_3740887_-	NA	NA|3717aa|down_5|NZ_CP018303.1_3741223_3752374_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP018303.1_3752617_3753412_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP018303.1_3753493_3753865_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|137aa|down_8|NZ_CP018303.1_3753762_3754173_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP018303.1_3754007_3754268_-	NA
GCF_001895765.1_ASM189576v1	NZ_CP018303	Mycobacterium tuberculosis strain I0004241-1, complete genome	16	4085217-4085305	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP018303.1_4075803_4076574_-,NA|119aa|up_3|NZ_CP018303.1_4081708_4082065_+,NA|52aa|up_2|NZ_CP018303.1_4082164_4082320_+,NA|233aa|up_0|NZ_CP018303.1_4084321_4085020_-,NA|126aa|down_6|NZ_CP018303.1_4090540_4090918_+	NA|288aa|up_9|NZ_CP018303.1_4074185_4075049_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP018303.1_4075803_4076574_-	NA	NA|549aa|up_7|NZ_CP018303.1_4076570_4078217_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP018303.1_4078213_4079077_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP018303.1_4079069_4079996_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP018303.1_4079997_4081623_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP018303.1_4081708_4082065_+	NA	NA|52aa|up_2|NZ_CP018303.1_4082164_4082320_+	NA	NA|652aa|up_1|NZ_CP018303.1_4082330_4084286_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP018303.1_4084321_4085020_-	NA	NA|173aa|down_0|NZ_CP018303.1_4085365_4085884_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP018303.1_4085884_4086868_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP018303.1_4086860_4088054_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP018303.1_4088059_4088881_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP018303.1_4089012_4089696_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP018303.1_4089695_4090433_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP018303.1_4090540_4090918_+	NA	NA|225aa|down_7|NZ_CP018303.1_4091016_4091691_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP018303.1_4091796_4092591_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP018303.1_4092597_4093053_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
