assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	1	369627-370325	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	369915-369956|369990-370022	NZ_CP018305.1_377946-377987|NZ_CP018305.1_376761-376793	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP018305.1_366639_366942_+,NA|161aa|down_1|NZ_CP018305.1_379735_380218_-,NA|410aa|down_5|NZ_CP018305.1_382334_383564_+	NA|262aa|up_9|NZ_CP018305.1_361334_362120_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP018305.1_362108_362912_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP018305.1_362921_364319_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP018305.1_364497_366273_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP018305.1_366415_366643_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP018305.1_366639_366942_+	NA	NA|74aa|up_3|NZ_CP018305.1_366989_367211_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP018305.1_367207_367633_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP018305.1_367768_368401_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP018305.1_368397_369306_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP018305.1_379076_379748_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP018305.1_379735_380218_-	NA	NA|239aa|down_2|NZ_CP018305.1_380275_380992_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP018305.1_381093_381750_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP018305.1_381819_382311_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP018305.1_382334_383564_+	NA	NA|621aa|down_6|NZ_CP018305.1_383718_385581_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP018305.1_385652_386039_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP018305.1_386041_386704_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP018305.1_386764_387649_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	2	635896-636033	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	635914-635931|635914-635931|635998-636015	NZ_CP018305.1_22567-22584|NZ_CP018305.1_1417961-1417978|NZ_CP018305.1_979678-979695	NA	3	3	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NZ_CP018305.1_626650_626812_-,NA|478aa|up_0|NZ_CP018305.1_632911_634345_-,NA|450aa|down_2|NZ_CP018305.1_637668_639018_-,NA|93aa|down_5|NZ_CP018305.1_640548_640827_-	NA|325aa|up_9|NZ_CP018305.1_624420_625395_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP018305.1_625436_626654_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP018305.1_626650_626812_-	NA	NA|106aa|up_6|NZ_CP018305.1_626858_627176_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|623aa|up_5|NZ_CP018305.1_627322_629191_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP018305.1_629086_630094_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP018305.1_630175_631054_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP018305.1_631070_631865_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP018305.1_631861_632902_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP018305.1_632911_634345_-	NA	NA|211aa|down_0|NZ_CP018305.1_636356_636989_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP018305.1_636985_637648_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP018305.1_637668_639018_-	NA	NA|381aa|down_3|NZ_CP018305.1_639029_640172_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP018305.1_640186_640489_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP018305.1_640548_640827_-	NA	NA|418aa|down_6|NZ_CP018305.1_640823_642077_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP018305.1_642196_642583_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP018305.1_642645_643530_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP018305.1_643625_644528_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	3	696603-696679	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP018305.1_682287_682503_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP018305.1_682499_682907_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP018305.1_682966_683653_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP018305.1_683806_686440_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP018305.1_686462_688850_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP018305.1_688987_689710_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP018305.1_689706_690504_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP018305.1_690505_691393_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP018305.1_691398_692613_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP018305.1_693636_695082_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP018305.1_697814_699365_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP018305.1_699416_699809_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP018305.1_699805_700063_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP018305.1_700245_701481_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP018305.1_701731_702145_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP018305.1_702141_702378_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP018305.1_702481_702988_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP018305.1_703101_703572_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP018305.1_703615_704377_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP018305.1_704433_704745_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	4	931811-932758	2	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	932594-932629|932594-932629|932594-932629	NZ_CP018305.1_679706-679671|NZ_CP018305.1_1219872-1219907|NZ_CP018305.1_2410505-2410470	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP018305.1_936768_937320_-,NA|81aa|down_9|NZ_CP018305.1_944141_944384_+	NA|685aa|up_9|NZ_CP018305.1_919447_921502_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP018305.1_921667_922837_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP018305.1_922924_923941_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP018305.1_924102_924744_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP018305.1_924824_925880_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP018305.1_925931_926324_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP018305.1_926381_926804_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP018305.1_926765_927056_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP018305.1_927160_928066_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP018305.1_928084_928900_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP018305.1_933027_935676_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP018305.1_936143_936788_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP018305.1_936768_937320_-	NA	NA|421aa|down_3|NZ_CP018305.1_937437_938699_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|218aa|down_4|NZ_CP018305.1_938827_939481_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_5|NZ_CP018305.1_939551_940580_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_6|NZ_CP018305.1_941268_942039_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_7|NZ_CP018305.1_942125_942938_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_8|NZ_CP018305.1_943005_943866_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_9|NZ_CP018305.1_944141_944384_+	NA
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	5	1197640-1197748	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP018305.1_1187007_1188639_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP018305.1_1188714_1189779_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP018305.1_1189831_1190305_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP018305.1_1190338_1191202_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP018305.1_1191206_1192064_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP018305.1_1192064_1193147_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP018305.1_1193227_1193647_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP018305.1_1193758_1194325_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP018305.1_1194321_1194717_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP018305.1_1194744_1196748_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP018305.1_1198833_1200597_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP018305.1_1200593_1201367_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP018305.1_1201378_1202416_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP018305.1_1202602_1203439_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP018305.1_1203554_1204406_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP018305.1_1204479_1205697_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP018305.1_1205749_1206694_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NZ_CP018305.1_1207090_1207984_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP018305.1_1208040_1209435_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP018305.1_1209636_1210359_+	pfam06271, RDD, RDD family
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	6	1576609-1577681	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1576809-1576830	NZ_CP018305.1_1218387-1218366	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP018305.1_1568372_1568690_+,NA	NA|103aa|up_9|NZ_CP018305.1_1565887_1566196_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP018305.1_1566192_1567812_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP018305.1_1568372_1568690_+	NA	NA|209aa|up_6|NZ_CP018305.1_1568824_1569451_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP018305.1_1569516_1569849_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP018305.1_1569864_1571121_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP018305.1_1571248_1572460_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP018305.1_1572532_1574011_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP018305.1_1574007_1575393_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP018305.1_1575470_1576505_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP018305.1_1578535_1578937_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP018305.1_1578933_1579191_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP018305.1_1579273_1580233_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP018305.1_1580257_1581220_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP018305.1_1581353_1581956_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP018305.1_1582036_1584004_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP018305.1_1584021_1584846_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP018305.1_1585014_1585497_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP018305.1_1585568_1586393_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP018305.1_1586589_1587528_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	7	2073794-2074048	3	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2073875-2073892|2073875-2073892|2073965-2073982	NZ_CP018305.1_404242-404225|NZ_CP018305.1_611968-611951|NZ_CP018305.1_3431423-3431406	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP018305.1_2073153_2073417_-,NA	NA|165aa|up_9|NZ_CP018305.1_2059559_2060054_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP018305.1_2060345_2061023_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP018305.1_2061381_2064207_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP018305.1_2064433_2065294_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP018305.1_2065334_2066201_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP018305.1_2066205_2068092_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP018305.1_2068107_2070141_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP018305.1_2070260_2072486_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP018305.1_2072761_2073157_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP018305.1_2073153_2073417_-	NA	NA|346aa|down_0|NZ_CP018305.1_2075185_2076223_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP018305.1_2076222_2077590_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP018305.1_2077763_2079200_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP018305.1_2079235_2080687_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP018305.1_2080716_2081667_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP018305.1_2081681_2082098_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP018305.1_2082375_2082798_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP018305.1_2082846_2083149_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP018305.1_2083145_2083460_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP018305.1_2083459_2085193_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	8	2154240-2154459	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP018305.1_2145490_2145898_-,NA|127aa|down_5|NZ_CP018305.1_2161975_2162356_-	NA|741aa|up_9|NZ_CP018305.1_2139458_2141681_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP018305.1_2141718_2142162_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP018305.1_2142275_2142869_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP018305.1_2142951_2143557_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP018305.1_2143656_2144661_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP018305.1_2144760_2145513_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP018305.1_2145490_2145898_-	NA	NA|368aa|up_2|NZ_CP018305.1_2146032_2147136_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP018305.1_2147135_2148332_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1412aa|up_0|NZ_CP018305.1_2148501_2152737_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP018305.1_2156486_2156951_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP018305.1_2157048_2157912_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP018305.1_2157949_2159221_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP018305.1_2159492_2160608_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP018305.1_2160598_2161939_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP018305.1_2161975_2162356_-	NA	NA|621aa|down_6|NZ_CP018305.1_2162512_2164375_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP018305.1_2164382_2164862_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP018305.1_2165098_2165872_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP018305.1_2165875_2166643_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	9	3103234-3104588	1,6,4	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-A,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-B,TypeIII-A,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP018305.1_3096513_3096768_-,NA|135aa|up_7|NZ_CP018305.1_3096915_3097320_+,NA|64aa|up_6|NZ_CP018305.1_3097316_3097508_+,NA|86aa|up_4|NZ_CP018305.1_3099094_3099352_+,NA|104aa|up_3|NZ_CP018305.1_3099456_3099768_+,NA|203aa|up_2|NZ_CP018305.1_3100187_3100796_+,NA	NA|92aa|up_9|NZ_CP018305.1_3096062_3096338_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP018305.1_3096513_3096768_-	NA	NA|135aa|up_7|NZ_CP018305.1_3096915_3097320_+	NA	NA|64aa|up_6|NZ_CP018305.1_3097316_3097508_+	NA	NA|385aa|up_5|NZ_CP018305.1_3097706_3098861_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP018305.1_3099094_3099352_+	NA	NA|104aa|up_3|NZ_CP018305.1_3099456_3099768_+	NA	NA|203aa|up_2|NZ_CP018305.1_3100187_3100796_+	NA	NA|470aa|up_1|NZ_CP018305.1_3100866_3102276_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP018305.1_3102272_3103085_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP018305.1_3104614_3105876_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP018305.1_3107496_3107838_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP018305.1_3107838_3108855_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP018305.1_3108867_3110016_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP018305.1_3110111_3111239_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP018305.1_3111235_3112144_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP018305.1_3112124_3112835_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP018305.1_3112844_3113219_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP018305.1_3113215_3115654_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NZ_CP018305.1_3115650_3116595_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	10	3105953-3107448	2,7,5	PILER-CR,CRISPRCasFinder,CRT	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-A,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	20,20,20	20	TypeIII-B,TypeIII-A,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP018305.1_3096513_3096768_-,NA|135aa|up_8|NZ_CP018305.1_3096915_3097320_+,NA|64aa|up_7|NZ_CP018305.1_3097316_3097508_+,NA|86aa|up_5|NZ_CP018305.1_3099094_3099352_+,NA|104aa|up_4|NZ_CP018305.1_3099456_3099768_+,NA|203aa|up_3|NZ_CP018305.1_3100187_3100796_+,NA	NA|85aa|up_9|NZ_CP018305.1_3096513_3096768_-	NA	NA|135aa|up_8|NZ_CP018305.1_3096915_3097320_+	NA	NA|64aa|up_7|NZ_CP018305.1_3097316_3097508_+	NA	NA|385aa|up_6|NZ_CP018305.1_3097706_3098861_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP018305.1_3099094_3099352_+	NA	NA|104aa|up_4|NZ_CP018305.1_3099456_3099768_+	NA	NA|203aa|up_3|NZ_CP018305.1_3100187_3100796_+	NA	NA|470aa|up_2|NZ_CP018305.1_3100866_3102276_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP018305.1_3102272_3103085_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP018305.1_3104614_3105876_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP018305.1_3107496_3107838_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP018305.1_3107838_3108855_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP018305.1_3108867_3110016_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP018305.1_3110111_3111239_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP018305.1_3111235_3112144_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP018305.1_3112124_3112835_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP018305.1_3112844_3113219_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP018305.1_3113215_3115654_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_8|NZ_CP018305.1_3115650_3116595_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP018305.1_3116772_3117318_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	11	3723591-3724270	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGNNNCCNCCGTNGCCGCC	23	0	0	NA	NA	NA	9	9	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|282aa|up_9|NZ_CP018305.1_3702992_3703838_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP018305.1_3704312_3704753_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP018305.1_3704786_3705656_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP018305.1_3705676_3706687_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP018305.1_3706971_3707604_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP018305.1_3707670_3708900_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP018305.1_3709182_3710532_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP018305.1_3710543_3711683_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP018305.1_3711679_3712411_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP018305.1_3712419_3719991_-	pfam00823, PPE, PPE family	NA|98aa|down_0|NZ_CP018305.1_3726181_3726475_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|282aa|down_1|NZ_CP018305.1_3726471_3727317_-	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional	NA|92aa|down_2|NZ_CP018305.1_3727440_3727716_+	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|86aa|down_3|NZ_CP018305.1_3727712_3727970_+	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system	NA|397aa|down_4|NZ_CP018305.1_3728011_3729202_+	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain	NA|123aa|down_5|NZ_CP018305.1_3729318_3729687_+	pfam00498, FHA, FHA domain	NA|184aa|down_6|NZ_CP018305.1_3729683_3730235_-	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|194aa|down_7|NZ_CP018305.1_3730241_3730823_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|123aa|down_8|NZ_CP018305.1_3730803_3731172_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|131aa|down_9|NZ_CP018305.1_3731149_3731542_-	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only]
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	12	3897695-3898325	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGNNCCGGCGGNNCCGGCGGC	25	4	4	3897819-3897859|3897885-3897931|3897957-3898003|3898029-3898087	NZ_CP018305.1_3897468-3897508|NZ_CP018305.1_3897525-3897571|NZ_CP018305.1_3898545-3898591|NZ_CP018305.1_3898617-3898675	NA	8	8	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP018305.1_3902311_3903151_+	NA|64aa|up_9|NZ_CP018305.1_3872455_3872647_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_8|NZ_CP018305.1_3872861_3874064_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_7|NZ_CP018305.1_3874088_3875210_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_6|NZ_CP018305.1_3875280_3876789_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1404aa|up_5|NZ_CP018305.1_3876959_3881171_+	pfam00934, PE, PE family	NA|2124aa|up_4|NZ_CP018305.1_3881461_3887833_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP018305.1_3887999_3889547_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP018305.1_3889543_3890380_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1563aa|up_1|NZ_CP018305.1_3890739_3895428_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP018305.1_3895556_3896213_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP018305.1_3899704_3901351_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP018305.1_3901424_3902216_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP018305.1_3902311_3903151_+	NA	NA|399aa|down_3|NZ_CP018305.1_3903205_3904402_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP018305.1_3904430_3905141_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP018305.1_3905205_3906249_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP018305.1_3906401_3907313_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP018305.1_3907328_3908393_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP018305.1_3908409_3909594_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP018305.1_3909635_3910667_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_001895785.1_ASM189578v1	NZ_CP018305	Mycobacterium tuberculosis strain M0018684-2, complete genome	13	4059070-4059158	8	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP018305.1_4049656_4050427_-,NA|119aa|up_3|NZ_CP018305.1_4055561_4055918_+,NA|52aa|up_2|NZ_CP018305.1_4056017_4056173_+,NA|233aa|up_0|NZ_CP018305.1_4058174_4058873_-,NA|126aa|down_6|NZ_CP018305.1_4064393_4064771_+	NA|288aa|up_9|NZ_CP018305.1_4048038_4048902_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP018305.1_4049656_4050427_-	NA	NA|549aa|up_7|NZ_CP018305.1_4050423_4052070_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP018305.1_4052066_4052930_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP018305.1_4052922_4053849_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP018305.1_4053850_4055476_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP018305.1_4055561_4055918_+	NA	NA|52aa|up_2|NZ_CP018305.1_4056017_4056173_+	NA	NA|652aa|up_1|NZ_CP018305.1_4056183_4058139_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP018305.1_4058174_4058873_-	NA	NA|173aa|down_0|NZ_CP018305.1_4059218_4059737_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP018305.1_4059737_4060721_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP018305.1_4060713_4061907_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP018305.1_4061912_4062734_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP018305.1_4062865_4063549_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP018305.1_4063548_4064286_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP018305.1_4064393_4064771_+	NA	NA|225aa|down_7|NZ_CP018305.1_4064869_4065544_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP018305.1_4065649_4066444_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP018305.1_4066450_4066906_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
