assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	1	334935-335045	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTGCCGCCGTTGCCGATC	24	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|61aa|up_0|NZ_CP018302.1_333270_333453_-,NA	NA|398aa|up_9|NZ_CP018302.1_323448_324642_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP018302.1_324677_326360_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP018302.1_326376_328572_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP018302.1_328685_329819_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP018302.1_329815_330436_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP018302.1_330532_331114_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP018302.1_331043_331769_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP018302.1_331858_332779_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP018302.1_332818_333247_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP018302.1_333270_333453_-	NA	NA|887aa|down_0|NZ_CP018302.1_336606_339267_-	pfam00934, PE, PE family	NA|838aa|down_1|NZ_CP018302.1_339516_342030_-	pfam00934, PE, PE family	NA|537aa|down_2|NZ_CP018302.1_342320_343931_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_3|NZ_CP018302.1_343954_344863_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_4|NZ_CP018302.1_345086_346982_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_5|NZ_CP018302.1_346978_348595_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_6|NZ_CP018302.1_348591_352584_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_7|NZ_CP018302.1_352580_352889_+	pfam00934, PE, PE family	NA|514aa|down_8|NZ_CP018302.1_352891_354433_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_9|NZ_CP018302.1_354481_354775_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	2	341061-341283	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|61aa|up_2|NZ_CP018302.1_333270_333453_-,NA	NA|732aa|up_9|NZ_CP018302.1_326376_328572_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_8|NZ_CP018302.1_328685_329819_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_7|NZ_CP018302.1_329815_330436_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_6|NZ_CP018302.1_330532_331114_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_5|NZ_CP018302.1_331043_331769_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_4|NZ_CP018302.1_331858_332779_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_3|NZ_CP018302.1_332818_333247_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_2|NZ_CP018302.1_333270_333453_-	NA	NA|932aa|up_1|NZ_CP018302.1_333547_336343_-	pfam00934, PE, PE family	NA|887aa|up_0|NZ_CP018302.1_336606_339267_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_CP018302.1_342320_343931_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP018302.1_343954_344863_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP018302.1_345086_346982_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP018302.1_346978_348595_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP018302.1_348591_352584_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP018302.1_352580_352889_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP018302.1_352891_354433_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP018302.1_354481_354775_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP018302.1_354804_355095_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP018302.1_355105_355993_+	pfam14011, ESX-1_EspG, EspG family
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	3	369420-370118	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	369708-369749|369783-369815	NZ_CP018302.1_377754-377795|NZ_CP018302.1_376569-376601	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|101aa|up_4|NZ_CP018302.1_366432_366735_+,NA|161aa|down_1|NZ_CP018302.1_379543_380026_-,NA|410aa|down_5|NZ_CP018302.1_382142_383372_+	NA|262aa|up_9|NZ_CP018302.1_361127_361913_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP018302.1_361901_362705_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP018302.1_362714_364112_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP018302.1_364290_366066_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP018302.1_366208_366436_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP018302.1_366432_366735_+	NA	NA|74aa|up_3|NZ_CP018302.1_366782_367004_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP018302.1_367000_367426_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP018302.1_367561_368194_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP018302.1_368190_369099_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP018302.1_378884_379556_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP018302.1_379543_380026_-	NA	NA|239aa|down_2|NZ_CP018302.1_380083_380800_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP018302.1_380901_381558_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP018302.1_381627_382119_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP018302.1_382142_383372_+	NA	NA|621aa|down_6|NZ_CP018302.1_383526_385389_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP018302.1_385460_385847_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP018302.1_385849_386512_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP018302.1_386572_387457_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	4	583433-583550	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GATGACCTGCGCCGACGACGATGCAGAGCGTAGCGATGAGG	41	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA|110aa|down_2|NZ_CP018302.1_586129_586459_-,NA|330aa|down_3|NZ_CP018302.1_586455_587445_-,NA|297aa|down_5|NZ_CP018302.1_588178_589069_-,NA|311aa|down_7|NZ_CP018302.1_590131_591064_+	NA|281aa|up_9|NZ_CP018302.1_571819_572662_-	cd07581, nitrilase_3, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases)	NA|175aa|up_8|NZ_CP018302.1_572843_573368_-	pfam10698, DUF2505, Protein of unknown function (DUF2505)	NA|370aa|up_7|NZ_CP018302.1_573394_574504_+	PRK13903, murB, UDP-N-acetylmuramate dehydrogenase	NA|452aa|up_6|NZ_CP018302.1_574565_575921_+	pfam17964, Big_10, Bacterial Ig domain	NA|252aa|up_5|NZ_CP018302.1_575901_576657_-	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]	NA|439aa|up_4|NZ_CP018302.1_576839_578156_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|481aa|up_3|NZ_CP018302.1_578203_579646_+	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase	NA|184aa|up_2|NZ_CP018302.1_579642_580194_+	pfam10722, YbjN, Putative bacterial sensory transduction regulator	NA|202aa|up_1|NZ_CP018302.1_580519_581125_+	TIGR00948, Hypothetical_protein_Rv0488/MT0507/Mb0498	NA|250aa|up_0|NZ_CP018302.1_581281_582031_+	PRK14120, gpmA, phosphoglyceromutase; Provisional	NA|228aa|down_0|NZ_CP018302.1_583563_584247_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|630aa|down_1|NZ_CP018302.1_584243_586133_-	pfam00732, GMC_oxred_N, GMC oxidoreductase	NA|110aa|down_2|NZ_CP018302.1_586129_586459_-	NA	NA|330aa|down_3|NZ_CP018302.1_586455_587445_-	NA	NA|243aa|down_4|NZ_CP018302.1_587449_588178_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|297aa|down_5|NZ_CP018302.1_588178_589069_-	NA	NA|329aa|down_6|NZ_CP018302.1_589148_590135_+	pfam02541, Ppx-GppA, Ppx/GppA phosphatase family	NA|311aa|down_7|NZ_CP018302.1_590131_591064_+	NA	NA|281aa|down_8|NZ_CP018302.1_591079_591922_+	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]	NA|292aa|down_9|NZ_CP018302.1_591937_592813_+	pfam13622, 4HBT_3, Thioesterase-like superfamily
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	5	694865-694941	3	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|136aa|up_9|NZ_CP018302.1_680760_681168_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP018302.1_681227_681914_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP018302.1_682067_684701_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP018302.1_684723_687111_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP018302.1_687248_687971_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP018302.1_687967_688765_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP018302.1_688766_689654_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP018302.1_689659_690874_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_1|NZ_CP018302.1_691897_693343_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|479aa|up_0|NZ_CP018302.1_693339_694776_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP018302.1_696076_697627_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP018302.1_697678_698071_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP018302.1_698067_698325_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP018302.1_698507_699743_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP018302.1_699993_700407_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP018302.1_700403_700640_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP018302.1_700743_701250_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP018302.1_701363_701834_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP018302.1_701877_702639_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP018302.1_702695_703007_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	6	843857-843979	3	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCCGCCGGCCCCGCCGGCCCCGCCGGTGCCG--------GCG	42	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|71aa|up_8|NZ_CP018302.1_833072_833285_+,NA|176aa|up_6|NZ_CP018302.1_835147_835675_+,NA|186aa|up_4|NZ_CP018302.1_837257_837815_-,NA|46aa|down_2|NZ_CP018302.1_845108_845246_-,NA|53aa|down_3|NZ_CP018302.1_845231_845390_+,NA|82aa|down_4|NZ_CP018302.1_845404_845650_+	NA|166aa|up_9|NZ_CP018302.1_832578_833076_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|71aa|up_8|NZ_CP018302.1_833072_833285_+	NA	NA|183aa|up_7|NZ_CP018302.1_833433_833982_+	TIGR03086, TIGR03086, TIGR03086 family protein	NA|176aa|up_6|NZ_CP018302.1_835147_835675_+	NA	NA|176aa|up_5|NZ_CP018302.1_836352_836880_+	pfam00934, PE, PE family	NA|186aa|up_4|NZ_CP018302.1_837257_837815_-	NA	NA|169aa|up_3|NZ_CP018302.1_837811_838318_-	pfam12728, HTH_17, Helix-turn-helix domain	NA|49aa|up_2|NZ_CP018302.1_838430_838577_-	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase	NA|176aa|up_1|NZ_CP018302.1_838525_839053_+	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase	NA|784aa|up_0|NZ_CP018302.1_839072_841424_+	pfam00934, PE, PE family	NA|86aa|down_0|NZ_CP018302.1_844318_844576_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|143aa|down_1|NZ_CP018302.1_844599_845028_+	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|46aa|down_2|NZ_CP018302.1_845108_845246_-	NA	NA|53aa|down_3|NZ_CP018302.1_845231_845390_+	NA	NA|82aa|down_4|NZ_CP018302.1_845404_845650_+	NA	NA|295aa|down_5|NZ_CP018302.1_845718_846603_-	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase	NA|391aa|down_6|NZ_CP018302.1_846613_847786_-	cd01162, IBD, Isobutyryl-CoA dehydrogenase	NA|511aa|down_7|NZ_CP018302.1_847792_849325_-	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2	NA|585aa|down_8|NZ_CP018302.1_849530_851285_+	pfam00934, PE, PE family	NA|646aa|down_9|NZ_CP018302.1_851474_853412_-	pfam00823, PPE, PPE family
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	7	966023-966274	4	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	63	1	1	966196-966251	NZ_CP018302.1_966324-966379	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|67aa|up_3|NZ_CP018302.1_964121_964322_+,NA	NA|158aa|up_9|NZ_CP018302.1_954698_955172_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_8|NZ_CP018302.1_955168_956362_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|404aa|up_7|NZ_CP018302.1_956518_957730_+	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|721aa|up_6|NZ_CP018302.1_957734_959897_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NZ_CP018302.1_959964_961593_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NZ_CP018302.1_961783_964054_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NZ_CP018302.1_964121_964322_+	NA	NA|168aa|up_2|NZ_CP018302.1_964331_964835_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NZ_CP018302.1_964831_965314_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NZ_CP018302.1_965310_965736_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NZ_CP018302.1_967424_967703_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|361aa|down_1|NZ_CP018302.1_967706_968789_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NZ_CP018302.1_968785_969175_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NZ_CP018302.1_969339_969747_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|610aa|down_4|NZ_CP018302.1_969865_971695_-	pfam00934, PE, PE family	NA|651aa|down_5|NZ_CP018302.1_971955_973908_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_6|NZ_CP018302.1_973996_975157_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_7|NZ_CP018302.1_975256_975745_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_8|NZ_CP018302.1_975741_977388_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|263aa|down_9|NZ_CP018302.1_977525_978314_+	pfam11228, DUF3027, Protein of unknown function (DUF3027)
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	8	1192774-1192882	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|544aa|up_9|NZ_CP018302.1_1182141_1183773_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP018302.1_1183848_1184913_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP018302.1_1184965_1185439_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP018302.1_1185472_1186336_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP018302.1_1186340_1187198_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP018302.1_1187198_1188281_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP018302.1_1188361_1188781_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP018302.1_1188892_1189459_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP018302.1_1189455_1189851_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP018302.1_1189878_1191882_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP018302.1_1193967_1195731_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP018302.1_1195727_1196501_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP018302.1_1196512_1197550_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP018302.1_1197736_1198573_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP018302.1_1198688_1199540_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP018302.1_1199613_1200831_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP018302.1_1200883_1201828_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NZ_CP018302.1_1202224_1203118_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP018302.1_1203174_1204569_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP018302.1_1204770_1205493_+	pfam06271, RDD, RDD family
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	9	1213408-1214264	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	78	1213791-1213812|1213836-1213851|1213974-1213995|1213974-1213995|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109|1214091-1214109	NZ_CP018302.1_2944699-2944678|NZ_CP018302.1_2078983-2078968|NZ_CP018302.1_840806-840827|NZ_CP018302.1_1219147-1219168|NZ_CP018302.1_677631-677613|NZ_CP018302.1_1214934-1214952|NZ_CP018302.1_1219120-1219138|NZ_CP018302.1_1219192-1219210|NZ_CP018302.1_1631864-1631846|NZ_CP018302.1_1634717-1634699|NZ_CP018302.1_1981641-1981623|NZ_CP018302.1_2051967-2051949|NZ_CP018302.1_2052414-2052396|NZ_CP018302.1_2052513-2052495|NZ_CP018302.1_2786332-2786314|NZ_CP018302.1_2789776-2789758|NZ_CP018302.1_150225-150243|NZ_CP018302.1_333893-333875|NZ_CP018302.1_335117-335099|NZ_CP018302.1_338176-338158|NZ_CP018302.1_338629-338611|NZ_CP018302.1_338680-338662|NZ_CP018302.1_338689-338671|NZ_CP018302.1_340960-340942|NZ_CP018302.1_341356-341338|NZ_CP018302.1_341385-341403|NZ_CP018302.1_341479-341461|NZ_CP018302.1_366010-365992|NZ_CP018302.1_446294-446276|NZ_CP018302.1_549625-549607|NZ_CP018302.1_626822-626840|NZ_CP018302.1_627044-627062|NZ_CP018302.1_676797-676779|NZ_CP018302.1_843589-843607|NZ_CP018302.1_929267-929285|NZ_CP018302.1_929309-929327|NZ_CP018302.1_1092429-1092447|NZ_CP018302.1_1093077-1093095|NZ_CP018302.1_1097147-1097129|NZ_CP018302.1_1214463-1214481|NZ_CP018302.1_1214853-1214871|NZ_CP018302.1_1215141-1215159|NZ_CP018302.1_1215159-1215177|NZ_CP018302.1_1219357-1219375|NZ_CP018302.1_1490420-1490402|NZ_CP018302.1_1620281-1620263|NZ_CP018302.1_1637437-1637419|NZ_CP018302.1_1637446-1637428|NZ_CP018302.1_1856466-1856448|NZ_CP018302.1_1856994-1856976|NZ_CP018302.1_1980915-1980897|NZ_CP018302.1_1991879-1991897|NZ_CP018302.1_2079181-2079163|NZ_CP018302.1_2295134-2295116|NZ_CP018302.1_2348472-2348454|NZ_CP018302.1_2409705-2409723|NZ_CP018302.1_2413792-2413774|NZ_CP018302.1_2557870-2557852|NZ_CP018302.1_2679060-2679078|NZ_CP018302.1_2779647-2779629|NZ_CP018302.1_2780229-2780211|NZ_CP018302.1_3038736-3038754|NZ_CP018302.1_3038835-3038853|NZ_CP018302.1_3689142-3689160|NZ_CP018302.1_3725246-3725228|NZ_CP018302.1_3725870-3725852|NZ_CP018302.1_3726113-3726095|NZ_CP018302.1_3726246-3726228|NZ_CP018302.1_3762444-3762462|NZ_CP018302.1_3762627-3762645|NZ_CP018302.1_3762795-3762813|NZ_CP018302.1_3888941-3888959|NZ_CP018302.1_3889304-3889322|NZ_CP018302.1_3890767-3890785|NZ_CP018302.1_3898014-3898032|NZ_CP018302.1_3903986-3904004|NZ_CP018302.1_3986309-3986291|NZ_CP018302.1_4048411-4048429	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|89aa|up_3|NZ_CP018302.1_1208840_1209107_+,NA|61aa|down_3|NZ_CP018302.1_1216727_1216910_+,NA|35aa|down_4|NZ_CP018302.1_1217019_1217124_+	NA|465aa|up_9|NZ_CP018302.1_1203174_1204569_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP018302.1_1204770_1205493_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP018302.1_1205524_1206691_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP018302.1_1206761_1207256_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP018302.1_1207441_1207876_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP018302.1_1207977_1208844_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP018302.1_1208840_1209107_+	NA	NA|674aa|up_2|NZ_CP018302.1_1209093_1211115_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP018302.1_1211213_1211942_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP018302.1_1212052_1212841_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP018302.1_1215542_1215863_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP018302.1_1216015_1216450_+	pfam00934, PE, PE family	NA|63aa|down_2|NZ_CP018302.1_1216527_1216716_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP018302.1_1216727_1216910_+	NA	NA|35aa|down_4|NZ_CP018302.1_1217019_1217124_+	NA	NA|152aa|down_5|NZ_CP018302.1_1217101_1217557_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|793aa|down_6|NZ_CP018302.1_1217971_1220350_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP018302.1_1220567_1221506_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP018302.1_1221893_1223174_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP018302.1_1223277_1224105_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	10	1573387-1574459	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|106aa|up_7|NZ_CP018302.1_1565150_1565468_+,NA	NA|103aa|up_9|NZ_CP018302.1_1562665_1562974_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP018302.1_1562970_1564590_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP018302.1_1565150_1565468_+	NA	NA|209aa|up_6|NZ_CP018302.1_1565602_1566229_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP018302.1_1566294_1566627_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP018302.1_1566642_1567899_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP018302.1_1568026_1569238_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP018302.1_1569310_1570789_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP018302.1_1570785_1572171_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP018302.1_1572248_1573283_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP018302.1_1575313_1575715_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP018302.1_1575711_1575969_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP018302.1_1576051_1577011_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP018302.1_1577035_1577998_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP018302.1_1578131_1578734_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP018302.1_1578814_1580782_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP018302.1_1580799_1581624_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP018302.1_1581792_1582275_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP018302.1_1582346_1583171_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP018302.1_1583367_1584306_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	11	2078653-2078907	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2078734-2078751|2078734-2078751|2078824-2078841	NZ_CP018302.1_404050-404033|NZ_CP018302.1_610193-610176|NZ_CP018302.1_3433892-3433875	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|88aa|up_0|NZ_CP018302.1_2078012_2078276_-,NA	NA|165aa|up_9|NZ_CP018302.1_2064362_2064857_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP018302.1_2065204_2065882_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP018302.1_2066240_2069066_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP018302.1_2069292_2070153_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP018302.1_2070193_2071060_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP018302.1_2071064_2072951_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP018302.1_2072966_2075000_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP018302.1_2075119_2077345_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP018302.1_2077620_2078016_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP018302.1_2078012_2078276_-	NA	NA|346aa|down_0|NZ_CP018302.1_2080035_2081073_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP018302.1_2081072_2082440_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP018302.1_2082613_2084050_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP018302.1_2084085_2085537_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP018302.1_2085566_2086517_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP018302.1_2086531_2086948_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP018302.1_2087225_2087648_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP018302.1_2087696_2087999_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP018302.1_2087995_2088310_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP018302.1_2088309_2090043_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	12	2159084-2159303	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|136aa|up_3|NZ_CP018302.1_2150340_2150748_-,NA|127aa|down_5|NZ_CP018302.1_2166819_2167200_-	NA|741aa|up_9|NZ_CP018302.1_2144308_2146531_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP018302.1_2146568_2147012_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP018302.1_2147125_2147719_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP018302.1_2147801_2148407_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP018302.1_2148506_2149511_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP018302.1_2149610_2150363_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP018302.1_2150340_2150748_-	NA	NA|368aa|up_2|NZ_CP018302.1_2150882_2151986_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP018302.1_2151985_2153182_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1410aa|up_0|NZ_CP018302.1_2153351_2157581_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP018302.1_2161330_2161795_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP018302.1_2161892_2162756_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP018302.1_2162793_2164065_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP018302.1_2164336_2165452_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP018302.1_2165442_2166783_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP018302.1_2166819_2167200_-	NA	NA|621aa|down_6|NZ_CP018302.1_2167356_2169219_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP018302.1_2169226_2169706_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP018302.1_2169942_2170716_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP018302.1_2170719_2171487_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	13	3103327-3104535	5,8,2	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-C,Type III-A,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	14,15,16	16	TypeIII-C,TypeIII-A,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_8|NZ_CP018302.1_3096606_3096861_-,NA|135aa|up_7|NZ_CP018302.1_3097008_3097413_+,NA|64aa|up_6|NZ_CP018302.1_3097409_3097601_+,NA|86aa|up_4|NZ_CP018302.1_3099187_3099445_+,NA|104aa|up_3|NZ_CP018302.1_3099549_3099861_+,NA|203aa|up_2|NZ_CP018302.1_3100280_3100889_+,NA	NA|92aa|up_9|NZ_CP018302.1_3096155_3096431_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP018302.1_3096606_3096861_-	NA	NA|135aa|up_7|NZ_CP018302.1_3097008_3097413_+	NA	NA|64aa|up_6|NZ_CP018302.1_3097409_3097601_+	NA	NA|385aa|up_5|NZ_CP018302.1_3097799_3098954_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP018302.1_3099187_3099445_+	NA	NA|104aa|up_3|NZ_CP018302.1_3099549_3099861_+	NA	NA|203aa|up_2|NZ_CP018302.1_3100280_3100889_+	NA	NA|470aa|up_1|NZ_CP018302.1_3100959_3102369_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP018302.1_3102365_3103178_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP018302.1_3104561_3105823_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP018302.1_3107550_3107892_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP018302.1_3107892_3108909_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP018302.1_3108921_3110070_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP018302.1_3110165_3111293_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP018302.1_3111289_3112198_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP018302.1_3112178_3112889_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP018302.1_3112898_3113273_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP018302.1_3113269_3115708_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NZ_CP018302.1_3115704_3116649_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	14	3105858-3107502	9,3,6	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Type III-C,Type III-A,Type III-D,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	22,22,21	22	TypeIII-C,TypeIII-A,TypeIII-D,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|85aa|up_9|NZ_CP018302.1_3096606_3096861_-,NA|135aa|up_8|NZ_CP018302.1_3097008_3097413_+,NA|64aa|up_7|NZ_CP018302.1_3097409_3097601_+,NA|86aa|up_5|NZ_CP018302.1_3099187_3099445_+,NA|104aa|up_4|NZ_CP018302.1_3099549_3099861_+,NA|203aa|up_3|NZ_CP018302.1_3100280_3100889_+,NA	NA|85aa|up_9|NZ_CP018302.1_3096606_3096861_-	NA	NA|135aa|up_8|NZ_CP018302.1_3097008_3097413_+	NA	NA|64aa|up_7|NZ_CP018302.1_3097409_3097601_+	NA	NA|385aa|up_6|NZ_CP018302.1_3097799_3098954_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP018302.1_3099187_3099445_+	NA	NA|104aa|up_4|NZ_CP018302.1_3099549_3099861_+	NA	NA|203aa|up_3|NZ_CP018302.1_3100280_3100889_+	NA	NA|470aa|up_2|NZ_CP018302.1_3100959_3102369_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP018302.1_3102365_3103178_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP018302.1_3104561_3105823_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP018302.1_3107550_3107892_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP018302.1_3107892_3108909_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP018302.1_3108921_3110070_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP018302.1_3110165_3111293_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP018302.1_3111289_3112198_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP018302.1_3112178_3112889_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP018302.1_3112898_3113273_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP018302.1_3113269_3115708_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_8|NZ_CP018302.1_3115704_3116649_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP018302.1_3116826_3117372_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	15	3728362-3729041	4	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	CCGCCGNNNCCNCCGTNGCCGCC	23	0	0	NA	NA	NA	9	9	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA,NA	NA|282aa|up_9|NZ_CP018302.1_3707649_3708495_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP018302.1_3708969_3709410_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP018302.1_3709443_3710313_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP018302.1_3710333_3711344_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP018302.1_3711628_3712261_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP018302.1_3712327_3713557_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP018302.1_3713839_3715189_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP018302.1_3715200_3716340_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP018302.1_3716336_3717068_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2538aa|up_0|NZ_CP018302.1_3717076_3724690_-	pfam00823, PPE, PPE family	NA|98aa|down_0|NZ_CP018302.1_3730952_3731246_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|282aa|down_1|NZ_CP018302.1_3731242_3732088_-	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional	NA|92aa|down_2|NZ_CP018302.1_3732211_3732487_+	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|86aa|down_3|NZ_CP018302.1_3732483_3732741_+	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system	NA|397aa|down_4|NZ_CP018302.1_3732782_3733973_+	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain	NA|123aa|down_5|NZ_CP018302.1_3734089_3734458_+	pfam00498, FHA, FHA domain	NA|184aa|down_6|NZ_CP018302.1_3734454_3735006_-	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown]	NA|194aa|down_7|NZ_CP018302.1_3735012_3735594_-	COG2229, COG2229, Predicted GTPase [General function prediction only]	NA|123aa|down_8|NZ_CP018302.1_3735574_3735943_-	pfam05331, DUF742, Protein of unknown function (DUF742)	NA|131aa|down_9|NZ_CP018302.1_3735920_3736313_-	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only]
GCF_001895805.1_ASM189580v1	NZ_CP018302	Mycobacterium tuberculosis strain I0004000-1, complete genome	16	4064828-4064916	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,DEDDh	NA|257aa|up_8|NZ_CP018302.1_4055414_4056185_-,NA|119aa|up_3|NZ_CP018302.1_4061319_4061676_+,NA|52aa|up_2|NZ_CP018302.1_4061775_4061931_+,NA|233aa|up_0|NZ_CP018302.1_4063932_4064631_-,NA|126aa|down_6|NZ_CP018302.1_4070151_4070529_+	NA|288aa|up_9|NZ_CP018302.1_4053796_4054660_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP018302.1_4055414_4056185_-	NA	NA|549aa|up_7|NZ_CP018302.1_4056181_4057828_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP018302.1_4057824_4058688_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP018302.1_4058680_4059607_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP018302.1_4059608_4061234_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP018302.1_4061319_4061676_+	NA	NA|52aa|up_2|NZ_CP018302.1_4061775_4061931_+	NA	NA|652aa|up_1|NZ_CP018302.1_4061941_4063897_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP018302.1_4063932_4064631_-	NA	NA|173aa|down_0|NZ_CP018302.1_4064976_4065495_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP018302.1_4065495_4066479_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP018302.1_4066471_4067665_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP018302.1_4067670_4068492_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP018302.1_4068623_4069307_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP018302.1_4069306_4070044_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP018302.1_4070151_4070529_+	NA	NA|225aa|down_7|NZ_CP018302.1_4070627_4071302_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP018302.1_4071407_4072202_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP018302.1_4072208_4072664_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
