assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	1	365915-366613	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366203-366244|366278-366310	NZ_CP018300.1_374264-374305|NZ_CP018300.1_373079-373111	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP018300.1_362927_363230_+,NA|161aa|down_1|NZ_CP018300.1_376053_376536_-,NA|410aa|down_5|NZ_CP018300.1_378652_379882_+	NA|262aa|up_9|NZ_CP018300.1_357622_358408_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP018300.1_358396_359200_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP018300.1_359209_360607_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP018300.1_360785_362561_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP018300.1_362703_362931_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP018300.1_362927_363230_+	NA	NA|74aa|up_3|NZ_CP018300.1_363277_363499_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP018300.1_363495_363921_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP018300.1_364056_364689_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP018300.1_364685_365594_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP018300.1_375394_376066_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP018300.1_376053_376536_-	NA	NA|239aa|down_2|NZ_CP018300.1_376593_377310_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP018300.1_377411_378068_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP018300.1_378137_378629_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP018300.1_378652_379882_+	NA	NA|621aa|down_6|NZ_CP018300.1_380036_381899_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP018300.1_381970_382357_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP018300.1_382359_383022_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP018300.1_383082_383967_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	2	668933-669044	2	CRISPRCasFinder	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CCGCCGTTGCCGCCGTTGCCGCCG	24	1	2	668999-669019|668999-669019	NZ_CP018300.1_836946-836926|NZ_CP018300.1_1855890-1855910	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|114aa|up_6|NZ_CP018300.1_661320_661662_-,NA|56aa|up_5|NZ_CP018300.1_661712_661880_-,NA|164aa|down_1|NZ_CP018300.1_673394_673886_-	NA|89aa|up_9|NZ_CP018300.1_657281_657548_+	pfam08940, DUF1918, Domain of unknown function (DUF1918)	NA|693aa|up_8|NZ_CP018300.1_657573_659652_+	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase	NA|444aa|up_7|NZ_CP018300.1_659765_661097_-	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only]	NA|114aa|up_6|NZ_CP018300.1_661320_661662_-	NA	NA|56aa|up_5|NZ_CP018300.1_661712_661880_-	NA	NA|464aa|up_4|NZ_CP018300.1_662129_663521_-	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional	NA|381aa|up_3|NZ_CP018300.1_663530_664673_-	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]	NA|389aa|up_2|NZ_CP018300.1_664857_666024_-	PRK07588, PRK07588, FAD-binding domain	csa3|435aa|up_1|NZ_CP018300.1_666126_667431_+	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein	NA|262aa|up_0|NZ_CP018300.1_667444_668230_+	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only]	NA|253aa|down_0|NZ_CP018300.1_672507_673266_+	pfam01927, Mut7-C, Mut7-C RNAse domain	NA|164aa|down_1|NZ_CP018300.1_673394_673886_-	NA	NA|72aa|down_2|NZ_CP018300.1_673979_674195_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|down_3|NZ_CP018300.1_674191_674599_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|down_4|NZ_CP018300.1_674658_675345_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|down_5|NZ_CP018300.1_675498_678132_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|down_6|NZ_CP018300.1_678154_680542_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|down_7|NZ_CP018300.1_680679_681402_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|down_8|NZ_CP018300.1_681398_682196_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|down_9|NZ_CP018300.1_682197_683085_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	3	669113-670090	3	CRISPRCasFinder	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CCGCCGTTGCCGCCGTTGCCGCCG	24	1	2	669569-669589|669569-669589	NZ_CP018300.1_2015088-2015108|NZ_CP018300.1_3907128-3907108	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|114aa|up_6|NZ_CP018300.1_661320_661662_-,NA|56aa|up_5|NZ_CP018300.1_661712_661880_-,NA|164aa|down_1|NZ_CP018300.1_673394_673886_-	NA|89aa|up_9|NZ_CP018300.1_657281_657548_+	pfam08940, DUF1918, Domain of unknown function (DUF1918)	NA|693aa|up_8|NZ_CP018300.1_657573_659652_+	PRK08665, PRK08665, vitamin B12-dependent ribonucleotide reductase	NA|444aa|up_7|NZ_CP018300.1_659765_661097_-	COG1926, COG1926, Predicted phosphoribosyltransferases [General function prediction only]	NA|114aa|up_6|NZ_CP018300.1_661320_661662_-	NA	NA|56aa|up_5|NZ_CP018300.1_661712_661880_-	NA	NA|464aa|up_4|NZ_CP018300.1_662129_663521_-	PRK12484, PRK12484, nicotinate phosphoribosyltransferase; Provisional	NA|381aa|up_3|NZ_CP018300.1_663530_664673_-	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane]	NA|389aa|up_2|NZ_CP018300.1_664857_666024_-	PRK07588, PRK07588, FAD-binding domain	csa3|435aa|up_1|NZ_CP018300.1_666126_667431_+	pfam08327, AHSA1, Activator of Hsp90 ATPase homolog 1-like protein	NA|262aa|up_0|NZ_CP018300.1_667444_668230_+	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only]	NA|253aa|down_0|NZ_CP018300.1_672507_673266_+	pfam01927, Mut7-C, Mut7-C RNAse domain	NA|164aa|down_1|NZ_CP018300.1_673394_673886_-	NA	NA|72aa|down_2|NZ_CP018300.1_673979_674195_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|down_3|NZ_CP018300.1_674191_674599_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|down_4|NZ_CP018300.1_674658_675345_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|down_5|NZ_CP018300.1_675498_678132_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|down_6|NZ_CP018300.1_678154_680542_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|down_7|NZ_CP018300.1_680679_681402_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|down_8|NZ_CP018300.1_681398_682196_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|down_9|NZ_CP018300.1_682197_683085_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	4	688295-688371	4	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP018300.1_673979_674195_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP018300.1_674191_674599_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP018300.1_674658_675345_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP018300.1_675498_678132_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP018300.1_678154_680542_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP018300.1_680679_681402_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP018300.1_681398_682196_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP018300.1_682197_683085_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP018300.1_683090_684305_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP018300.1_685328_686774_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP018300.1_689506_691057_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP018300.1_691108_691501_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP018300.1_691497_691755_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP018300.1_691937_693173_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP018300.1_693423_693837_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP018300.1_693833_694070_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP018300.1_694173_694680_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP018300.1_694793_695264_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP018300.1_695307_696069_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP018300.1_696125_696437_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	5	922012-922959	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	922795-922830|922795-922830|922795-922830	NZ_CP018300.1_671398-671363|NZ_CP018300.1_1209716-1209751|NZ_CP018300.1_2410522-2410487	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|81aa|down_7|NZ_CP018300.1_933519_933762_+	NA|685aa|up_9|NZ_CP018300.1_909648_911703_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP018300.1_911868_913038_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP018300.1_913125_914142_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP018300.1_914303_914945_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP018300.1_915025_916081_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP018300.1_916132_916525_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP018300.1_916582_917005_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP018300.1_916966_917257_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP018300.1_917361_918267_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP018300.1_918285_919101_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP018300.1_923228_925877_-	pfam00934, PE, PE family	NA|421aa|down_1|NZ_CP018300.1_926815_928077_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|218aa|down_2|NZ_CP018300.1_928205_928859_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_3|NZ_CP018300.1_928929_929958_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_4|NZ_CP018300.1_930646_931417_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_5|NZ_CP018300.1_931503_932316_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_6|NZ_CP018300.1_932383_933244_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_7|NZ_CP018300.1_933519_933762_+	NA	NA|431aa|down_8|NZ_CP018300.1_934038_935331_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|335aa|down_9|NZ_CP018300.1_935314_936319_+	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	6	1187265-1187373	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP018300.1_1176632_1178264_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP018300.1_1178339_1179404_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP018300.1_1179456_1179930_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP018300.1_1179963_1180827_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP018300.1_1180831_1181689_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP018300.1_1181689_1182772_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP018300.1_1182852_1183272_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP018300.1_1183383_1183950_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP018300.1_1183946_1184342_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP018300.1_1184369_1186373_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP018300.1_1188458_1190222_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP018300.1_1190218_1190992_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP018300.1_1191003_1192041_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP018300.1_1192227_1193064_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP018300.1_1193179_1194031_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP018300.1_1194104_1195322_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP018300.1_1195374_1196319_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|298aa|down_7|NZ_CP018300.1_1196715_1197609_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP018300.1_1197665_1199060_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP018300.1_1199261_1199984_+	pfam06271, RDD, RDD family
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	7	1484788-1484907	1	PILER-CR	no	DinG	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type IV-A	AACCCGCCGGTGCCGCCGGCACCGCCGGCG	30	1	1	1484818-1484836	NZ_CP018300.1_399081-399099	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|99aa|up_3|NZ_CP018300.1_1480678_1480975_+,NA	NA|166aa|up_9|NZ_CP018300.1_1472830_1473328_-	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional	NA|497aa|up_8|NZ_CP018300.1_1473324_1474815_-	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]	NA|542aa|up_7|NZ_CP018300.1_1474895_1476521_-	cd07302, CHD, cyclase homology domain	NA|536aa|up_6|NZ_CP018300.1_1476590_1478198_-	cd07302, CHD, cyclase homology domain	NA|568aa|up_5|NZ_CP018300.1_1478210_1479914_-	COG2114, CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]	NA|224aa|up_4|NZ_CP018300.1_1479984_1480656_+	PRK03298, PRK03298, endonuclease NucS	NA|99aa|up_3|NZ_CP018300.1_1480678_1480975_+	NA	NA|153aa|up_2|NZ_CP018300.1_1481009_1481468_-	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE)	NA|394aa|up_1|NZ_CP018300.1_1481546_1482728_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|305aa|up_0|NZ_CP018300.1_1482857_1483772_+	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|732aa|down_0|NZ_CP018300.1_1485813_1488009_-	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB	NA|702aa|down_1|NZ_CP018300.1_1488016_1490122_-	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins	NA|864aa|down_2|NZ_CP018300.1_1490260_1492852_+	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase	DinG|665aa|down_3|NZ_CP018300.1_1492891_1494886_-	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]	NA|449aa|down_4|NZ_CP018300.1_1494909_1496256_-	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated	NA|102aa|down_5|NZ_CP018300.1_1496357_1496663_+	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed	NA|219aa|down_6|NZ_CP018300.1_1496622_1497279_+	pfam09438, DUF2017, Domain of unknown function (DUF2017)	NA|345aa|down_7|NZ_CP018300.1_1497295_1498330_+	COG3191, DmpA, L-aminopeptidase/D-esterase [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|147aa|down_8|NZ_CP018300.1_1498337_1498778_+	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding)	NA|94aa|down_9|NZ_CP018300.1_1498799_1499081_+	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	8	1566525-1567596	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1566725-1566746	NZ_CP018300.1_1208012-1207991	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP018300.1_1558288_1558606_+,NA	NA|103aa|up_9|NZ_CP018300.1_1555803_1556112_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP018300.1_1556108_1557728_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP018300.1_1558288_1558606_+	NA	NA|209aa|up_6|NZ_CP018300.1_1558740_1559367_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP018300.1_1559432_1559765_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP018300.1_1559780_1561037_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP018300.1_1561164_1562376_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP018300.1_1562448_1563927_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP018300.1_1563923_1565309_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP018300.1_1565386_1566421_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP018300.1_1568450_1568852_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP018300.1_1568848_1569106_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP018300.1_1569188_1570148_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP018300.1_1570172_1571135_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP018300.1_1571268_1571871_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP018300.1_1571951_1573919_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP018300.1_1573936_1574761_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP018300.1_1574929_1575412_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP018300.1_1575483_1576308_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP018300.1_1576504_1577443_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	9	1631148-1631374	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_7|NZ_CP018300.1_1617426_1617540_-,NA|288aa|down_2|NZ_CP018300.1_1635200_1636064_+	NA|767aa|up_9|NZ_CP018300.1_1614093_1616394_+	TIGR00509, Trimethylamine-N-oxide_reductase_1, molybdopterin guanine dinucleotide-containing S/N-oxide reductases	NA|162aa|up_8|NZ_CP018300.1_1616509_1616995_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_7|NZ_CP018300.1_1617426_1617540_-	NA	NA|248aa|up_6|NZ_CP018300.1_1618012_1618756_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP018300.1_1618752_1619664_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP018300.1_1619716_1621261_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP018300.1_1621257_1622379_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP018300.1_1622395_1624498_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1408aa|up_1|NZ_CP018300.1_1624936_1629160_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP018300.1_1629561_1630488_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP018300.1_1632901_1634167_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP018300.1_1634194_1635181_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP018300.1_1635200_1636064_+	NA	NA|311aa|down_3|NZ_CP018300.1_1636013_1636946_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP018300.1_1637057_1637843_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP018300.1_1637839_1638781_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP018300.1_1638936_1640712_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP018300.1_1640759_1641566_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP018300.1_1641562_1644103_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP018300.1_1644099_1645293_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	10	2071290-2071826	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGTNNCCGCCGNTGCC	21	3	5	2071554-2071571|2071554-2071571|2071653-2071670|2071653-2071670|2071743-2071760	NZ_CP018300.1_3903766-3903749|NZ_CP018300.1_3903862-3903845|NZ_CP018300.1_400560-400543|NZ_CP018300.1_603633-603616|NZ_CP018300.1_3435527-3435510	NA	9	9	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP018300.1_2070931_2071195_-,NA	NA|165aa|up_9|NZ_CP018300.1_2057337_2057832_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP018300.1_2058123_2058801_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP018300.1_2059159_2061985_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP018300.1_2062211_2063072_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP018300.1_2063112_2063979_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP018300.1_2063983_2065870_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP018300.1_2065885_2067919_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP018300.1_2068038_2070264_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP018300.1_2070539_2070935_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP018300.1_2070931_2071195_-	NA	NA|346aa|down_0|NZ_CP018300.1_2072963_2074001_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP018300.1_2074000_2075368_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP018300.1_2075541_2076978_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP018300.1_2077013_2078465_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP018300.1_2078494_2079445_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP018300.1_2079459_2079876_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP018300.1_2080153_2080576_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP018300.1_2080624_2080927_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP018300.1_2080923_2081238_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP018300.1_2081237_2082971_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	11	2151803-2152022	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP018300.1_2143260_2143668_-,NA|127aa|down_5|NZ_CP018300.1_2159538_2159919_-	NA|741aa|up_9|NZ_CP018300.1_2137228_2139451_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP018300.1_2139488_2139932_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP018300.1_2140045_2140639_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP018300.1_2140721_2141327_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP018300.1_2141426_2142431_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP018300.1_2142530_2143283_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP018300.1_2143260_2143668_-	NA	NA|368aa|up_2|NZ_CP018300.1_2143802_2144906_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP018300.1_2144905_2146102_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1343aa|up_0|NZ_CP018300.1_2146271_2150300_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP018300.1_2154049_2154514_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP018300.1_2154611_2155475_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP018300.1_2155512_2156784_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP018300.1_2157055_2158171_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP018300.1_2158161_2159502_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP018300.1_2159538_2159919_-	NA	NA|621aa|down_6|NZ_CP018300.1_2160075_2161938_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP018300.1_2161945_2162425_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP018300.1_2162661_2163435_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP018300.1_2163438_2164206_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	12	3103398-3104752	3,8,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-A,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	15,17,18	18	TypeIII-B,TypeIII-A,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP018300.1_3096677_3096932_-,NA|135aa|up_7|NZ_CP018300.1_3097079_3097484_+,NA|64aa|up_6|NZ_CP018300.1_3097480_3097672_+,NA|86aa|up_4|NZ_CP018300.1_3099258_3099516_+,NA|104aa|up_3|NZ_CP018300.1_3099620_3099932_+,NA|203aa|up_2|NZ_CP018300.1_3100351_3100960_+,NA	NA|92aa|up_9|NZ_CP018300.1_3096226_3096502_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP018300.1_3096677_3096932_-	NA	NA|135aa|up_7|NZ_CP018300.1_3097079_3097484_+	NA	NA|64aa|up_6|NZ_CP018300.1_3097480_3097672_+	NA	NA|385aa|up_5|NZ_CP018300.1_3097870_3099025_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP018300.1_3099258_3099516_+	NA	NA|104aa|up_3|NZ_CP018300.1_3099620_3099932_+	NA	NA|203aa|up_2|NZ_CP018300.1_3100351_3100960_+	NA	NA|470aa|up_1|NZ_CP018300.1_3101030_3102440_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP018300.1_3102436_3103249_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP018300.1_3104778_3106040_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP018300.1_3107732_3108074_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP018300.1_3108074_3109091_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP018300.1_3109103_3110252_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP018300.1_3110347_3111475_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP018300.1_3111471_3112380_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP018300.1_3112360_3113071_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP018300.1_3113080_3113455_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP018300.1_3113451_3115890_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NZ_CP018300.1_3115886_3116831_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	13	3106117-3107684	4,9,4	PILER-CR,CRISPRCasFinder,CRT	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-A,Type III-D,Type III-C	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	21,21,21	21	TypeIII-B,TypeIII-A,TypeIII-D,TypeIII-C	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP018300.1_3096677_3096932_-,NA|135aa|up_8|NZ_CP018300.1_3097079_3097484_+,NA|64aa|up_7|NZ_CP018300.1_3097480_3097672_+,NA|86aa|up_5|NZ_CP018300.1_3099258_3099516_+,NA|104aa|up_4|NZ_CP018300.1_3099620_3099932_+,NA|203aa|up_3|NZ_CP018300.1_3100351_3100960_+,NA	NA|85aa|up_9|NZ_CP018300.1_3096677_3096932_-	NA	NA|135aa|up_8|NZ_CP018300.1_3097079_3097484_+	NA	NA|64aa|up_7|NZ_CP018300.1_3097480_3097672_+	NA	NA|385aa|up_6|NZ_CP018300.1_3097870_3099025_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP018300.1_3099258_3099516_+	NA	NA|104aa|up_4|NZ_CP018300.1_3099620_3099932_+	NA	NA|203aa|up_3|NZ_CP018300.1_3100351_3100960_+	NA	NA|470aa|up_2|NZ_CP018300.1_3101030_3102440_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP018300.1_3102436_3103249_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP018300.1_3104778_3106040_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP018300.1_3107732_3108074_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP018300.1_3108074_3109091_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP018300.1_3109103_3110252_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP018300.1_3110347_3111475_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP018300.1_3111471_3112380_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP018300.1_3112360_3113071_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP018300.1_3113080_3113455_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP018300.1_3113451_3115890_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_8|NZ_CP018300.1_3115886_3116831_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP018300.1_3117008_3117554_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	14	3724836-3725683	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGNNNCCNCCGTNNCCGCC	23	0	0	NA	NA	NA	11	11	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP018300.1_3739556_3739844_-,NA|87aa|down_9|NZ_CP018300.1_3752964_3753225_-	NA|282aa|up_9|NZ_CP018300.1_3704213_3705059_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP018300.1_3705533_3705974_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP018300.1_3706007_3706877_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP018300.1_3706897_3707908_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP018300.1_3708192_3708825_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP018300.1_3708891_3710121_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP018300.1_3710403_3711753_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP018300.1_3711764_3712904_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP018300.1_3712900_3713632_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2538aa|up_0|NZ_CP018300.1_3713640_3721254_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP018300.1_3727426_3727684_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP018300.1_3727939_3737413_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP018300.1_3738038_3738485_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|273aa|down_3|NZ_CP018300.1_3738521_3739340_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP018300.1_3739556_3739844_-	NA	NA|3717aa|down_5|NZ_CP018300.1_3740180_3751331_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP018300.1_3751574_3752369_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP018300.1_3752450_3752822_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|137aa|down_8|NZ_CP018300.1_3752719_3753130_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP018300.1_3752964_3753225_-	NA
GCF_001895845.1_ASM189584v1	NZ_CP018300	Mycobacterium tuberculosis strain I0002353-6, complete genome	15	4084902-4084990	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP018300.1_4075488_4076259_-,NA|119aa|up_3|NZ_CP018300.1_4081393_4081750_+,NA|52aa|up_2|NZ_CP018300.1_4081849_4082005_+,NA|233aa|up_0|NZ_CP018300.1_4084006_4084705_-,NA|126aa|down_6|NZ_CP018300.1_4090225_4090603_+	NA|288aa|up_9|NZ_CP018300.1_4073870_4074734_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP018300.1_4075488_4076259_-	NA	NA|549aa|up_7|NZ_CP018300.1_4076255_4077902_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP018300.1_4077898_4078762_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP018300.1_4078754_4079681_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP018300.1_4079682_4081308_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP018300.1_4081393_4081750_+	NA	NA|52aa|up_2|NZ_CP018300.1_4081849_4082005_+	NA	NA|652aa|up_1|NZ_CP018300.1_4082015_4083971_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP018300.1_4084006_4084705_-	NA	NA|173aa|down_0|NZ_CP018300.1_4085050_4085569_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP018300.1_4085569_4086553_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP018300.1_4086545_4087739_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP018300.1_4087744_4088566_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP018300.1_4088697_4089381_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP018300.1_4089380_4090118_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP018300.1_4090225_4090603_+	NA	NA|225aa|down_7|NZ_CP018300.1_4090701_4091376_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP018300.1_4091481_4092276_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP018300.1_4092282_4092738_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
