assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	1	618140-618257	1	CRISPRCasFinder	no		cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Orphan	TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	40	0	0	NA	NA	NA	1	1	Orphan	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA,NA|55aa|down_0|NZ_CP010213.1_618330_618495_-	NA|115aa|up_9|NZ_CP010213.1_605861_606206_-	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional	NA|313aa|up_8|NZ_CP010213.1_606394_607333_+	PRK10341, PRK10341, transcriptional regulator TdcA	NA|330aa|up_7|NZ_CP010213.1_607431_608421_+	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA|444aa|up_6|NZ_CP010213.1_608442_609774_+	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional	NA|403aa|up_5|NZ_CP010213.1_609799_611008_+	PRK12379, PRK12379, propionate kinase	NA|765aa|up_4|NZ_CP010213.1_611041_613336_+	cd01678, PFL1, Pyruvate formate lyase 1	NA|130aa|up_3|NZ_CP010213.1_613349_613739_+	PRK11401, PRK11401, enamine/imine deaminase	NA|455aa|up_2|NZ_CP010213.1_613810_615175_+	PRK15040, PRK15040, L-serine ammonia-lyase	NA|444aa|up_1|NZ_CP010213.1_615449_616781_+	TIGR00814, membrane_transport_protein_YhjV, serine transporter	NA|437aa|up_0|NZ_CP010213.1_616808_618119_+	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism]	NA|55aa|down_0|NZ_CP010213.1_618330_618495_-	NA	NA|234aa|down_1|NZ_CP010213.1_618517_619219_-	COG1741, COG1741, Pirin-related protein [General function prediction only]	NA|299aa|down_2|NZ_CP010213.1_619323_620220_+	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold	NA|119aa|down_3|NZ_CP010213.1_620270_620627_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|122aa|down_4|NZ_CP010213.1_620868_621234_-	COG3152, COG3152, Predicted membrane protein [Function unknown]	NA|329aa|down_5|NZ_CP010213.1_621526_622513_-	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]	NA|161aa|down_6|NZ_CP010213.1_622582_623065_-	COG2259, COG2259, Predicted membrane protein [Function unknown]	NA|100aa|down_7|NZ_CP010213.1_623160_623460_-	pfam13997, YqjK, YqjK-like protein	NA|135aa|down_8|NZ_CP010213.1_623449_623854_-	COG5393, COG5393, Predicted membrane protein [Function unknown]	NA|102aa|down_9|NZ_CP010213.1_623856_624162_-	COG4575, ElaB, Uncharacterized conserved protein [Function unknown]
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	2	1153844-1154604	2,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Type I-E	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	12,12,10	12	TypeI-E	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA|121aa|up_3|NZ_CP010213.1_1150740_1151103_-,NA	NA|745aa|up_9|NZ_CP010213.1_1143676_1145911_+	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|83aa|up_8|NZ_CP010213.1_1145988_1146237_+	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|112aa|up_7|NZ_CP010213.1_1146236_1146572_+	PRK09907, PRK09907, endoribonuclease MazF	NA|264aa|up_6|NZ_CP010213.1_1146642_1147434_+	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|546aa|up_5|NZ_CP010213.1_1147661_1149299_+	PRK05380, pyrG, CTP synthetase; Validated	NA|433aa|up_4|NZ_CP010213.1_1149386_1150685_+	PRK00077, eno, enolase; Provisional	NA|121aa|up_3|NZ_CP010213.1_1150740_1151103_-	NA	NA|302aa|up_2|NZ_CP010213.1_1151138_1152044_-	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|201aa|up_1|NZ_CP010213.1_1152057_1152660_-	COG1704, LemA, Uncharacterized conserved protein [Function unknown]	NA|224aa|up_0|NZ_CP010213.1_1152832_1153504_+	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|122aa|down_0|NZ_CP010213.1_1155836_1156202_-	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS)	NA|600aa|down_1|NZ_CP010213.1_1156517_1158317_+	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	NA|571aa|down_2|NZ_CP010213.1_1158316_1160029_+	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit	NA|245aa|down_3|NZ_CP010213.1_1160102_1160837_+	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|51aa|down_4|NZ_CP010213.1_1161101_1161254_+	pfam01848, HOK_GEF, Hok/gef family	cas3|900aa|down_5|NZ_CP010213.1_1161447_1164147_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas8e|521aa|down_6|NZ_CP010213.1_1164244_1165807_+	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cse2gr11|180aa|down_7|NZ_CP010213.1_1165803_1166343_+	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2	cas7|352aa|down_8|NZ_CP010213.1_1166354_1167410_+	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cas5|249aa|down_9|NZ_CP010213.1_1167420_1168167_+	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	3	1170106-1170622	2,3,2	PILER-CR,CRISPRCasFinder,CRT	no	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Type I-E	GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG,GTGTTCCCCGCGCCAGCGGGGATAAACCG	29,29,29	0	0	NA	NA	I-E:I-E:I-E	8,8,8	8	TypeI-E	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA,NA	NA|245aa|up_9|NZ_CP010213.1_1160102_1160837_+	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|51aa|up_8|NZ_CP010213.1_1161101_1161254_+	pfam01848, HOK_GEF, Hok/gef family	cas3|900aa|up_7|NZ_CP010213.1_1161447_1164147_+	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	cas8e|521aa|up_6|NZ_CP010213.1_1164244_1165807_+	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cse2gr11|180aa|up_5|NZ_CP010213.1_1165803_1166343_+	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2	cas7|352aa|up_4|NZ_CP010213.1_1166354_1167410_+	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cas5|249aa|up_3|NZ_CP010213.1_1167420_1168167_+	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas6e|217aa|up_2|NZ_CP010213.1_1168148_1168799_+	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas1|307aa|up_1|NZ_CP010213.1_1168795_1169716_+	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas2|98aa|up_0|NZ_CP010213.1_1169715_1170009_+	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	NA|346aa|down_0|NZ_CP010213.1_1170703_1171741_-	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|303aa|down_1|NZ_CP010213.1_1171992_1172901_+	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|476aa|down_2|NZ_CP010213.1_1172902_1174330_+	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|202aa|down_3|NZ_CP010213.1_1174329_1174935_+	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|108aa|down_4|NZ_CP010213.1_1174984_1175308_+	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|104aa|down_5|NZ_CP010213.1_1175501_1175813_+	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|237aa|down_6|NZ_CP010213.1_1175831_1176542_+	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|160aa|down_7|NZ_CP010213.1_1176541_1177021_+	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|350aa|down_8|NZ_CP010213.1_1177017_1178067_+	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|254aa|down_9|NZ_CP010213.1_1178047_1178809_+	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	4	2384611-2384734	4	CRISPRCasFinder	no	DEDDh	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Unclear	CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	43	0	0	NA	NA	NA	1	1	Orphan	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA,NA|30aa|down_7|NZ_CP010213.1_2393630_2393720_+	NA|471aa|up_9|NZ_CP010213.1_2374064_2375477_-	PRK09206, PRK09206, pyruvate kinase PykF	NA|70aa|up_8|NZ_CP010213.1_2376033_2376243_+	PRK10292, PRK10292, fumarate hydratase FumD	NA|209aa|up_7|NZ_CP010213.1_2376698_2377325_+	PRK09898, PRK09898, ferredoxin-like protein	NA|701aa|up_6|NZ_CP010213.1_2377345_2379448_+	PRK09849, PRK09849, putative oxidoreductase; Provisional	NA|216aa|up_5|NZ_CP010213.1_2379451_2380099_+	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein	NA|223aa|up_4|NZ_CP010213.1_2380162_2380831_+	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein	NA|262aa|up_3|NZ_CP010213.1_2380827_2381613_+	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional	NA|271aa|up_2|NZ_CP010213.1_2381616_2382429_+	PRK09946, PRK09946, hypothetical protein; Provisional	NA|535aa|up_1|NZ_CP010213.1_2382440_2384045_-	PRK09897, PRK09897, FAD-NAD(P)-binding protein	NA|102aa|up_0|NZ_CP010213.1_2384170_2384476_-	PRK11118, PRK11118, putative monooxygenase; Provisional	NA|419aa|down_0|NZ_CP010213.1_2385048_2386305_+	PRK09945, PRK09945, hypothetical protein; Provisional	NA|458aa|down_1|NZ_CP010213.1_2386345_2387719_-	PRK01766, PRK01766, multidrug efflux protein; Reviewed	NA|214aa|down_2|NZ_CP010213.1_2387933_2388575_+	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional	NA|383aa|down_3|NZ_CP010213.1_2388614_2389763_-	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase	NA|404aa|down_4|NZ_CP010213.1_2390053_2391265_-	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter	NA|311aa|down_5|NZ_CP010213.1_2391377_2392310_+	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional	NA|342aa|down_6|NZ_CP010213.1_2392306_2393332_-	PRK10703, PRK10703, HTH-type transcriptional repressor PurR	NA|30aa|down_7|NZ_CP010213.1_2393630_2393720_+	NA	NA|390aa|down_8|NZ_CP010213.1_2393885_2395055_+	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|194aa|down_9|NZ_CP010213.1_2395200_2395782_-	PRK10543, PRK10543, superoxide dismutase [Fe]
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	5	3011636-3011727	5	CRISPRCasFinder	no		cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Orphan	CCACCTTTTTTACCTGCTTCAGATGC	26	0	0	NA	NA	NA	1	1	Orphan	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA|60aa|up_7|NZ_CP010213.1_3005969_3006149_-,NA|186aa|down_1|NZ_CP010213.1_3015206_3015764_+,NA|94aa|down_2|NZ_CP010213.1_3015765_3016047_+,NA|72aa|down_3|NZ_CP010213.1_3016046_3016262_+,NA|108aa|down_5|NZ_CP010213.1_3016704_3017028_+,NA|68aa|down_6|NZ_CP010213.1_3018329_3018533_+,NA|258aa|down_8|NZ_CP010213.1_3020929_3021703_+	NA|1321aa|up_9|NZ_CP010213.1_3001150_3005113_+	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed	NA|213aa|up_8|NZ_CP010213.1_3005152_3005791_-	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional	NA|60aa|up_7|NZ_CP010213.1_3005969_3006149_-	NA	NA|364aa|up_6|NZ_CP010213.1_3006078_3007170_+	TIGR03612, RutA, pyrimidine utilization protein A	NA|231aa|up_5|NZ_CP010213.1_3007169_3007862_+	TIGR03614, RutB, pyrimidine utilization protein B	NA|129aa|up_4|NZ_CP010213.1_3007873_3008260_+	TIGR03610, RutC, pyrimidine utilization protein C	NA|267aa|up_3|NZ_CP010213.1_3008267_3009068_+	TIGR03611, RutD, pyrimidine utilization protein D	NA|197aa|up_2|NZ_CP010213.1_3009077_3009668_+	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional	NA|165aa|up_1|NZ_CP010213.1_3009678_3010173_+	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F	NA|443aa|up_0|NZ_CP010213.1_3010193_3011522_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|183aa|down_0|NZ_CP010213.1_3012762_3013311_+	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain	NA|186aa|down_1|NZ_CP010213.1_3015206_3015764_+	NA	NA|94aa|down_2|NZ_CP010213.1_3015765_3016047_+	NA	NA|72aa|down_3|NZ_CP010213.1_3016046_3016262_+	NA	NA|96aa|down_4|NZ_CP010213.1_3016258_3016546_+	pfam13392, HNH_3, HNH endonuclease	NA|108aa|down_5|NZ_CP010213.1_3016704_3017028_+	NA	NA|68aa|down_6|NZ_CP010213.1_3018329_3018533_+	NA	NA|708aa|down_7|NZ_CP010213.1_3018641_3020765_+	COG3941, COG3941, Mu-like prophage protein [General function prediction only]	NA|258aa|down_8|NZ_CP010213.1_3020929_3021703_+	NA	NA|548aa|down_9|NZ_CP010213.1_3021722_3023366_-	pfam07508, Recombinase, Recombinase
GCF_001901165.1_ASM190116v1	NZ_CP010213	Escherichia coli strain M15, complete genome	6	3327456-3327600	6	CRISPRCasFinder	no		cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	Orphan	GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	52	0	0	NA	NA	NA	1	1	Orphan	cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4,RT,PrimPol	NA,NA	NA|330aa|up_9|NZ_CP010213.1_3315354_3316344_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|303aa|up_8|NZ_CP010213.1_3316740_3317649_+	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related	NA|674aa|up_7|NZ_CP010213.1_3317840_3319862_-	PRK05298, PRK05298, excinuclease ABC subunit UvrB	NA|226aa|up_6|NZ_CP010213.1_3320440_3321118_-	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD	NA|252aa|up_5|NZ_CP010213.1_3321110_3321866_-	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional	NA|385aa|up_4|NZ_CP010213.1_3321852_3323007_-	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed	NA|347aa|up_3|NZ_CP010213.1_3323003_3324044_-	PRK15108, PRK15108, biotin synthase; Provisional	NA|430aa|up_2|NZ_CP010213.1_3324130_3325420_+	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated	NA|159aa|up_1|NZ_CP010213.1_3325478_3325955_+	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional	NA|428aa|up_0|NZ_CP010213.1_3326106_3327390_+	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase	NA|754aa|down_0|NZ_CP010213.1_3327623_3329885_-	PRK11413, PRK11413, putative hydratase; Provisional	NA|478aa|down_1|NZ_CP010213.1_3330067_3331501_-	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region	NA|351aa|down_2|NZ_CP010213.1_3331576_3332629_-	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase	NA|318aa|down_3|NZ_CP010213.1_3332812_3333766_+	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|332aa|down_4|NZ_CP010213.1_3333806_3334802_-	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional	NA|273aa|down_5|NZ_CP010213.1_3334956_3335775_+	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional	NA|353aa|down_6|NZ_CP010213.1_3335775_3336834_-	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC	NA|230aa|down_7|NZ_CP010213.1_3336836_3337526_-	PRK09421, modB, molybdate ABC transporter permease subunit	NA|258aa|down_8|NZ_CP010213.1_3337525_3338299_-	PRK10677, modA, molybdate transporter periplasmic protein; Provisional	NA|50aa|down_9|NZ_CP010213.1_3338465_3338615_-	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ
