assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002012185.1_ASM201218v1	NZ_CP018962	Escherichia coli strain Ecol_422 chromosome, complete genome	1	90962-91663	1,1,1	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	Type I-E	CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC,CGGTTTATCCCCGCTGGCGCGGGGAACTC	29,29,29	0	0	NA	NA	I-E:I-E:I-E	11,11,8	11	TypeI-E	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA,NA	NA|254aa|up_9|NZ_CP018962.1_82773_83535_-	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional	NA|350aa|up_8|NZ_CP018962.1_83515_84565_-	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|160aa|up_7|NZ_CP018962.1_84561_85041_-	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|237aa|up_6|NZ_CP018962.1_85040_85751_-	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|104aa|up_5|NZ_CP018962.1_85769_86081_-	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|108aa|up_4|NZ_CP018962.1_86274_86598_-	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|202aa|up_3|NZ_CP018962.1_86647_87253_-	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|476aa|up_2|NZ_CP018962.1_87252_88680_-	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|303aa|up_1|NZ_CP018962.1_88681_89590_-	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|346aa|up_0|NZ_CP018962.1_89841_90879_+	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	NA|226aa|down_0|NZ_CP018962.1_91780_92458_+	pfam01527, HTH_Tnp_1, Transposase	NA|524aa|down_1|NZ_CP018962.1_93601_95173_+	pfam03050, DDE_Tnp_IS66, Transposase IS66 family	cas2|95aa|down_2|NZ_CP018962.1_95252_95537_-	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	cas1|306aa|down_3|NZ_CP018962.1_95538_96456_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|200aa|down_4|NZ_CP018962.1_96471_97071_-	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas5|225aa|down_5|NZ_CP018962.1_97057_97732_-	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI	cas7|364aa|down_6|NZ_CP018962.1_97734_98826_-	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cse2gr11|161aa|down_7|NZ_CP018962.1_98838_99321_-	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2	cas8e|495aa|down_8|NZ_CP018962.1_99313_100798_-	PRK09693, PRK09693, Cascade antiviral complex protein; Validated	cas3|889aa|down_9|NZ_CP018962.1_101236_103903_-	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3
GCF_002012185.1_ASM201218v1	NZ_CP018962	Escherichia coli strain Ecol_422 chromosome, complete genome	2	120698-121091	2,2,2	PILER-CR,CRISPRCasFinder,CRT	no	cas3	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	Unclear	GGTTTATCCCCGCTGGCGCGGGGAAC,GGTTTATCCCCGCTGGCGCGGGGAACAC,GGTTTATCCCCGCTGGCGCGGGGAACAC	26,28,28	0	0	NA	NA	I-E:I-E:I-E	6,6,6	6	Unclear	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA,NA|47aa|down_1|NZ_CP018962.1_122240_122381_+	NA|424aa|up_9|NZ_CP018962.1_109340_110612_+	PRK10015, PRK10015, oxidoreductase; Provisional	NA|87aa|up_8|NZ_CP018962.1_110602_110863_+	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|192aa|up_7|NZ_CP018962.1_110879_111455_+	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|287aa|up_6|NZ_CP018962.1_111602_112463_-	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion]	NA|260aa|up_5|NZ_CP018962.1_112459_113239_-	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|446aa|up_4|NZ_CP018962.1_113216_114554_-	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily	NA|485aa|up_3|NZ_CP018962.1_114647_116102_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|262aa|up_2|NZ_CP018962.1_116171_116957_-	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|426aa|up_1|NZ_CP018962.1_117275_118553_+	cd06174, MFS, Major Facilitator Superfamily	NA|493aa|up_0|NZ_CP018962.1_118579_120058_+	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|224aa|down_0|NZ_CP018962.1_121430_122102_-	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|47aa|down_1|NZ_CP018962.1_122240_122381_+	NA	NA|291aa|down_2|NZ_CP018962.1_122394_123267_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|433aa|down_3|NZ_CP018962.1_123326_124625_-	PRK00077, eno, enolase; Provisional	NA|546aa|down_4|NZ_CP018962.1_124712_126350_-	PRK05380, pyrG, CTP synthetase; Validated	NA|264aa|down_5|NZ_CP018962.1_126577_127369_-	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|112aa|down_6|NZ_CP018962.1_127439_127775_-	PRK09907, PRK09907, endoribonuclease MazF	NA|83aa|down_7|NZ_CP018962.1_127774_128023_-	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE	NA|745aa|down_8|NZ_CP018962.1_128100_130335_-	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional	NA|434aa|down_9|NZ_CP018962.1_130382_131684_-	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
GCF_002012185.1_ASM201218v1	NZ_CP018962	Escherichia coli strain Ecol_422 chromosome, complete genome	3	1743821-1743970	3	CRISPRCasFinder	no		csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	Orphan	CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	54	0	0	NA	NA	NA	1	1	Orphan	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA|556aa|up_6|NZ_CP018962.1_1735054_1736722_+,NA	NA|238aa|up_9|NZ_CP018962.1_1732957_1733671_-	PRK12742, PRK12742, SDR family oxidoreductase	NA|198aa|up_8|NZ_CP018962.1_1733741_1734335_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|151aa|up_7|NZ_CP018962.1_1734479_1734932_+	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]	NA|556aa|up_6|NZ_CP018962.1_1735054_1736722_+	NA	NA|335aa|up_5|NZ_CP018962.1_1736778_1737783_-	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional	NA|139aa|up_4|NZ_CP018962.1_1737944_1738361_+	PRK11191, PRK11191, ribonuclease E inhibitor RraB	NA|168aa|up_3|NZ_CP018962.1_1738406_1738910_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|399aa|up_2|NZ_CP018962.1_1739102_1740299_+	COG4269, COG4269, Predicted membrane protein [Function unknown]	NA|952aa|up_1|NZ_CP018962.1_1740354_1743210_-	PRK05729, valS, valyl-tRNA synthetase; Reviewed	NA|148aa|up_0|NZ_CP018962.1_1743209_1743653_-	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated	NA|504aa|down_0|NZ_CP018962.1_1744006_1745518_-	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional	NA|367aa|down_1|NZ_CP018962.1_1745784_1746885_+	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional	NA|361aa|down_2|NZ_CP018962.1_1746884_1747967_+	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional	NA|501aa|down_3|NZ_CP018962.1_1748085_1749588_-	pfam05872, DUF853, Bacterial protein of unknown function (DUF853)	NA|333aa|down_4|NZ_CP018962.1_1749665_1750664_-	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators	NA|440aa|down_5|NZ_CP018962.1_1750730_1752050_-	TIGR00791, Gluconate_permease, gluconate transporter	NA|255aa|down_6|NZ_CP018962.1_1752114_1752879_-	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional	NA|344aa|down_7|NZ_CP018962.1_1752902_1753934_-	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional	NA|188aa|down_8|NZ_CP018962.1_1754150_1754714_+	PRK09825, idnK, gluconokinase	NA|340aa|down_9|NZ_CP018962.1_1754717_1755737_-	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)
GCF_002012185.1_ASM201218v1	NZ_CP018962	Escherichia coli strain Ecol_422 chromosome, complete genome	4	2516189-2516285	4	CRISPRCasFinder	no		csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	Orphan	GCTTGACGCGTCTTATCAGGCCTACAA	27	0	0	NA	NA	NA	1	1	Orphan	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA,NA	NA|454aa|up_9|NZ_CP018962.1_2503969_2505331_+	PRK08044, PRK08044, allantoinase AllB	NA|434aa|up_8|NZ_CP018962.1_2505387_2506689_+	PRK11412, PRK11412, uracil/xanthine transporter	NA|382aa|up_7|NZ_CP018962.1_2506710_2507856_+	PRK09932, PRK09932, glycerate 3-kinase	NA|262aa|up_6|NZ_CP018962.1_2508083_2508869_-	TIGR03214, ura-cupin, putative allantoin catabolism protein	NA|412aa|up_5|NZ_CP018962.1_2508879_2510115_-	TIGR03176, AllC, allantoate amidohydrolase	NA|350aa|up_4|NZ_CP018962.1_2510136_2511186_-	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional	NA|556aa|up_3|NZ_CP018962.1_2511502_2513170_+	PRK06091, PRK06091, membrane protein FdrA; Validated	NA|420aa|up_2|NZ_CP018962.1_2513179_2514439_+	pfam06545, DUF1116, Protein of unknown function (DUF1116)	NA|272aa|up_1|NZ_CP018962.1_2514449_2515265_+	pfam11392, DUF2877, Protein of unknown function (DUF2877)	NA|298aa|up_0|NZ_CP018962.1_2515261_2516155_+	PRK09411, PRK09411, carbamate kinase; Reviewed	NA|356aa|down_0|NZ_CP018962.1_2516349_2517417_-	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed	NA|170aa|down_1|NZ_CP018962.1_2517413_2517923_-	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]	NA|241aa|down_2|NZ_CP018962.1_2518040_2518763_-	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional	NA|165aa|down_3|NZ_CP018962.1_2518765_2519260_-	PRK10791, PRK10791, peptidylprolyl isomerase B	NA|462aa|down_4|NZ_CP018962.1_2519433_2520819_+	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated	NA|174aa|down_5|NZ_CP018962.1_2520854_2521376_-	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only]	NA|71aa|down_6|NZ_CP018962.1_2521483_2521696_-	PRK11507, PRK11507, ribosome-associated protein YbcJ	NA|289aa|down_7|NZ_CP018962.1_2521697_2522564_-	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	NA|181aa|down_8|NZ_CP018962.1_2523034_2523577_+	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA	NA|231aa|down_9|NZ_CP018962.1_2523796_2524489_+	PRK15195, PRK15195, molecular chaperone FimC
GCF_002012185.1_ASM201218v1	NZ_CP018962	Escherichia coli strain Ecol_422 chromosome, complete genome	5	4344983-4345109	5	CRISPRCasFinder	no		csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	Orphan	TTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGC	39	0	0	NA	NA	NA	1	1	Orphan	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA,NA|105aa|down_3|NZ_CP018962.1_4349673_4349988_+	NA|395aa|up_9|NZ_CP018962.1_4323890_4325075_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|259aa|up_8|NZ_CP018962.1_4325148_4325925_-	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown]	NA|550aa|up_7|NZ_CP018962.1_4325929_4327579_-	COG5445, COG5445, Predicted secreted protein [Function unknown]	NA|1465aa|up_6|NZ_CP018962.1_4327579_4331974_-	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only]	NA|208aa|up_5|NZ_CP018962.1_4332117_4332741_-	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown]	NA|563aa|up_4|NZ_CP018962.1_4332737_4334426_-	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown]	NA|876aa|up_3|NZ_CP018962.1_4334574_4337202_-	PRK05560, PRK05560, DNA gyrase subunit A; Validated	NA|241aa|up_2|NZ_CP018962.1_4337348_4338071_+	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA|1251aa|up_1|NZ_CP018962.1_4338198_4341951_-	PRK09752, PRK09752, AIDA-I family autotransporter YfaL	NA|762aa|up_0|NZ_CP018962.1_4342646_4344932_+	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha	NA|377aa|down_0|NZ_CP018962.1_4345165_4346296_+	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed	NA|85aa|down_1|NZ_CP018962.1_4346295_4346550_+	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein	NA|217aa|down_2|NZ_CP018962.1_4346603_4347254_-	PRK09902, PRK09902, lipopolysaccharide kinase InaA	NA|105aa|down_3|NZ_CP018962.1_4349673_4349988_+	NA	NA|359aa|down_4|NZ_CP018962.1_4350206_4351283_-	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional	NA|453aa|down_5|NZ_CP018962.1_4351287_4352646_-	PRK11273, glpT, glycerol-3-phosphate transporter	NA|543aa|down_6|NZ_CP018962.1_4352918_4354547_+	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA|420aa|down_7|NZ_CP018962.1_4354536_4355796_+	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]	NA|397aa|down_8|NZ_CP018962.1_4355792_4356983_+	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	NA|300aa|down_9|NZ_CP018962.1_4357175_4358075_+	PRK09956, PRK09956, ISNCY family transposase
GCF_002012185.1_ASM201218v1	NZ_CP018961	Escherichia coli strain Ecol_422 plasmid pEC422_1, complete sequence	1	276922-277868	1	CRISPRCasFinder	no	RT,DinG	c2c9_V-U4,RT,DinG	Unclear	CCGATAACCCCCGCATGCGGGGGGAATAC	29	0	0	NA	NA	NA	15	15	Orphan	csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK,DEDDh,RT,DinG,c2c9_V-U4	NA|211aa|up_8|NZ_CP018961.1_266490_267123_-,NA|87aa|up_5|NZ_CP018961.1_270615_270876_+,NA|236aa|down_1|NZ_CP018961.1_278969_279677_-,NA|264aa|down_4|NZ_CP018961.1_282116_282908_-,NA|137aa|down_7|NZ_CP018961.1_285335_285746_-,NA|136aa|down_8|NZ_CP018961.1_285775_286183_-,NA|132aa|down_9|NZ_CP018961.1_286192_286588_-	NA|468aa|up_9|NZ_CP018961.1_265058_266462_+	pfam13565, HTH_32, Homeodomain-like domain	NA|211aa|up_8|NZ_CP018961.1_266490_267123_-	NA	NA|447aa|up_7|NZ_CP018961.1_267375_268716_-	pfam13518, HTH_28, Helix-turn-helix domain	NA|394aa|up_6|NZ_CP018961.1_268863_270045_+	pfam00665, rve, Integrase core domain	NA|87aa|up_5|NZ_CP018961.1_270615_270876_+	NA	NA|157aa|up_4|NZ_CP018961.1_270985_271456_-	pfam08808, RES, RES domain	NA|148aa|up_3|NZ_CP018961.1_271452_271896_-	TIGR02293, conserved_protein_of_unknown_function, putative toxin-antitoxin system antitoxin component, TIGR02293 family	NA|424aa|up_2|NZ_CP018961.1_271996_273268_-	PRK03609, umuC, translesion error-prone DNA polymerase V subunit UmuC	NA|141aa|up_1|NZ_CP018961.1_273267_273690_-	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit	RT|495aa|up_0|NZ_CP018961.1_273775_275260_-	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase	NA|264aa|down_0|NZ_CP018961.1_277933_278725_-	pfam08317, Spc7, Spc7 kinetochore protein	NA|236aa|down_1|NZ_CP018961.1_278969_279677_-	NA	DinG|625aa|down_2|NZ_CP018961.1_279670_281545_-	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]	NA|189aa|down_3|NZ_CP018961.1_281547_282114_-	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e	NA|264aa|down_4|NZ_CP018961.1_282116_282908_-	NA	NA|138aa|down_5|NZ_CP018961.1_282970_283384_-	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|335aa|down_6|NZ_CP018961.1_283960_284965_-	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|137aa|down_7|NZ_CP018961.1_285335_285746_-	NA	NA|136aa|down_8|NZ_CP018961.1_285775_286183_-	NA	NA|132aa|down_9|NZ_CP018961.1_286192_286588_-	NA
