assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	1	1823557-1823689	1	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	ACCGGACCCCGTGGGCCAACCGGAC	25	0	0	NA	NA	NA	2	2	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|301aa|up_8|NZ_CP018627.1_1813815_1814718_-,NA|232aa|up_7|NZ_CP018627.1_1814714_1815410_-,NA	NA|287aa|up_9|NZ_CP018627.1_1812709_1813570_-	pfam03631, Virul_fac_BrkB, Virulence factor BrkB	NA|301aa|up_8|NZ_CP018627.1_1813815_1814718_-	NA	NA|232aa|up_7|NZ_CP018627.1_1814714_1815410_-	NA	NA|141aa|up_6|NZ_CP018627.1_1815423_1815846_-	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane]	NA|335aa|up_5|NZ_CP018627.1_1816085_1817090_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|254aa|up_4|NZ_CP018627.1_1817155_1817917_-	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription]	NA|549aa|up_3|NZ_CP018627.1_1818045_1819692_+	cd01154, AidB, Proteins involved in DNA damage response, similar to the AidB gene product	NA|262aa|up_2|NZ_CP018627.1_1819718_1820504_+	PRK08259, PRK08259, crotonase/enoyl-CoA hydratase family protein	NA|257aa|up_1|NZ_CP018627.1_1821459_1822230_+	pfam14023, DUF4239, Protein of unknown function (DUF4239)	NA|431aa|up_0|NZ_CP018627.1_1822192_1823485_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|284aa|down_0|NZ_CP018627.1_1823737_1824589_-	COG1409, Icc, Predicted phosphohydrolases [General function prediction only]	NA|154aa|down_1|NZ_CP018627.1_1824695_1825157_+	pfam00582, Usp, Universal stress protein family	NA|71aa|down_2|NZ_CP018627.1_1825241_1825454_+	pfam07311, Dodecin, Dodecin	NA|356aa|down_3|NZ_CP018627.1_1825503_1826571_-	cd08589, PI-PLCc_SaPLC1_like, Catalytic domain of Streptomyces antibioticus phosphatidylinositol-specific phospholipase C1-like proteins	NA|363aa|down_4|NZ_CP018627.1_1826802_1827891_-	cd05240, UDP_G4E_3_SDR_e, UDP-glucose 4 epimerase (G4E), subgroup 3, extended (e) SDRs	NA|613aa|down_5|NZ_CP018627.1_1828113_1829952_-	PRK05899, PRK05899, transketolase; Reviewed	NA|440aa|down_6|NZ_CP018627.1_1829979_1831299_-	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|404aa|down_7|NZ_CP018627.1_1831439_1832651_-	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]	NA|289aa|down_8|NZ_CP018627.1_1832841_1833708_-	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair]	NA|938aa|down_9|NZ_CP018627.1_1833867_1836681_+	cd09818, PIOX_like, Animal heme oxidases similar to plant pathogen-inducible oxygenases
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	2	2448404-2448851	2	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GTGAGGGCACCGAGGCCGCCCACCGATGCGGGCA	34	0	0	NA	NA	NA	6	6	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|200aa|up_6|NZ_CP018627.1_2439616_2440216_-,NA|201aa|up_5|NZ_CP018627.1_2440219_2440822_-,NA|88aa|up_3|NZ_CP018627.1_2443737_2444001_-,NA|133aa|up_1|NZ_CP018627.1_2446308_2446707_-,NA|70aa|down_0|NZ_CP018627.1_2449555_2449765_+,NA|236aa|down_5|NZ_CP018627.1_2460024_2460732_+,NA|72aa|down_6|NZ_CP018627.1_2461237_2461453_+,NA|219aa|down_8|NZ_CP018627.1_2462418_2463075_+	NA|192aa|up_9|NZ_CP018627.1_2435831_2436407_+	cd19110, AKR_AKR1E1-2, AKR1E family of aldo-keto reductase (AKR)	NA|275aa|up_8|NZ_CP018627.1_2437749_2438574_+	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease	NA|92aa|up_7|NZ_CP018627.1_2439460_2439736_+	pfam13683, rve_3, Integrase core domain	NA|200aa|up_6|NZ_CP018627.1_2439616_2440216_-	NA	NA|201aa|up_5|NZ_CP018627.1_2440219_2440822_-	NA	NA|193aa|up_4|NZ_CP018627.1_2443145_2443724_-	pfam12158, DUF3592, Protein of unknown function (DUF3592)	NA|88aa|up_3|NZ_CP018627.1_2443737_2444001_-	NA	NA|290aa|up_2|NZ_CP018627.1_2444005_2444875_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|133aa|up_1|NZ_CP018627.1_2446308_2446707_-	NA	NA|283aa|up_0|NZ_CP018627.1_2446703_2447552_-	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|70aa|down_0|NZ_CP018627.1_2449555_2449765_+	NA	NA|352aa|down_1|NZ_CP018627.1_2453688_2454744_-	pfam13358, DDE_3, DDE superfamily endonuclease	NA|255aa|down_2|NZ_CP018627.1_2454862_2455627_+	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase	NA|317aa|down_3|NZ_CP018627.1_2455644_2456595_-	cd07730, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|391aa|down_4|NZ_CP018627.1_2458499_2459672_-	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal	NA|236aa|down_5|NZ_CP018627.1_2460024_2460732_+	NA	NA|72aa|down_6|NZ_CP018627.1_2461237_2461453_+	NA	NA|267aa|down_7|NZ_CP018627.1_2461496_2462296_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|219aa|down_8|NZ_CP018627.1_2462418_2463075_+	NA	NA|365aa|down_9|NZ_CP018627.1_2463098_2464193_-	pfam13358, DDE_3, DDE superfamily endonuclease
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	3	2531307-2531396	3	CRISPRCasFinder	no	DEDDh	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Unclear	GGCCGCACCCCCGCGGGTGCGGGGAGCAG	29	1	1	2531336-2531367	NZ_CP018627.1_5395762-5395793	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|418aa|up_3|NZ_CP018627.1_2524552_2525806_-,NA|133aa|down_1|NZ_CP018627.1_2532839_2533238_+,NA|125aa|down_5|NZ_CP018627.1_2540058_2540433_+,NA|50aa|down_6|NZ_CP018627.1_2541041_2541191_-,NA|84aa|down_8|NZ_CP018627.1_2543680_2543932_+,NA|73aa|down_9|NZ_CP018627.1_2544482_2544701_-	NA|347aa|up_9|NZ_CP018627.1_2516785_2517826_+	PRK14544, PRK14544, nucleoside diphosphate kinase; Provisional	NA|395aa|up_8|NZ_CP018627.1_2517852_2519037_+	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B	DEDDh|201aa|up_7|NZ_CP018627.1_2519033_2519636_+	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family	NA|200aa|up_6|NZ_CP018627.1_2519629_2520229_+	pfam13521, AAA_28, AAA domain	NA|261aa|up_5|NZ_CP018627.1_2520225_2521008_+	cd19088, AKR_AKR13B1, AKR13B family of aldo-keto reductase (AKR)	NA|713aa|up_4|NZ_CP018627.1_2521995_2524134_+	sd00006, TPR, Tetratricopeptide repeat	NA|418aa|up_3|NZ_CP018627.1_2524552_2525806_-	NA	NA|1043aa|up_2|NZ_CP018627.1_2526087_2529216_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|141aa|up_1|NZ_CP018627.1_2529623_2530046_-	pfam13683, rve_3, Integrase core domain	NA|360aa|up_0|NZ_CP018627.1_2530175_2531255_+	pfam13683, rve_3, Integrase core domain	NA|283aa|down_0|NZ_CP018627.1_2531994_2532843_+	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|133aa|down_1|NZ_CP018627.1_2532839_2533238_+	NA	NA|356aa|down_2|NZ_CP018627.1_2534360_2535428_+	pfam13683, rve_3, Integrase core domain	NA|158aa|down_3|NZ_CP018627.1_2535502_2535976_+	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|224aa|down_4|NZ_CP018627.1_2539049_2539721_-	pfam07510, DUF1524, Protein of unknown function (DUF1524)	NA|125aa|down_5|NZ_CP018627.1_2540058_2540433_+	NA	NA|50aa|down_6|NZ_CP018627.1_2541041_2541191_-	NA	NA|136aa|down_7|NZ_CP018627.1_2542996_2543404_+	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only]	NA|84aa|down_8|NZ_CP018627.1_2543680_2543932_+	NA	NA|73aa|down_9|NZ_CP018627.1_2544482_2544701_-	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	4	2824286-2824361	4	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GGGAGGGGTGCCCATCAGCGCTCGT	25	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|103aa|up_5|NZ_CP018627.1_2818123_2818432_-,NA|65aa|down_2|NZ_CP018627.1_2827955_2828150_+	NA|534aa|up_9|NZ_CP018627.1_2811421_2813023_+	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]	NA|412aa|up_8|NZ_CP018627.1_2813195_2814431_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|977aa|up_7|NZ_CP018627.1_2814427_2817358_+	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed	NA|152aa|up_6|NZ_CP018627.1_2817605_2818061_-	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of  thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides	NA|103aa|up_5|NZ_CP018627.1_2818123_2818432_-	NA	NA|425aa|up_4|NZ_CP018627.1_2818469_2819744_-	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]	NA|351aa|up_3|NZ_CP018627.1_2819772_2820825_-	pfam12852, Cupin_6, Cupin	NA|406aa|up_2|NZ_CP018627.1_2820917_2822135_+	PRK10213, nepI, purine ribonucleoside efflux pump NepI	NA|316aa|up_1|NZ_CP018627.1_2822300_2823248_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|290aa|up_0|NZ_CP018627.1_2823294_2824164_-	cd08023, GH16_laminarinase_like, Laminarinase, member of the glycosyl hydrolase family 16	NA|418aa|down_0|NZ_CP018627.1_2825851_2827105_-	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|141aa|down_1|NZ_CP018627.1_2827291_2827714_-	sd00045, ANK, ankyrin repeats	NA|65aa|down_2|NZ_CP018627.1_2827955_2828150_+	NA	NA|543aa|down_3|NZ_CP018627.1_2828151_2829780_+	pfam03737, RraA-like, Aldolase/RraA	NA|508aa|down_4|NZ_CP018627.1_2829890_2831414_-	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|219aa|down_5|NZ_CP018627.1_2831510_2832167_+	COG2364, COG2364, Predicted membrane protein [Function unknown]	NA|126aa|down_6|NZ_CP018627.1_2832423_2832801_+	pfam13397, RbpA, RNA polymerase-binding protein	NA|201aa|down_7|NZ_CP018627.1_2832990_2833593_-	pfam04186, FxsA, FxsA cytoplasmic membrane protein	NA|145aa|down_8|NZ_CP018627.1_2833995_2834430_+	pfam04066, MrpF_PhaF, Multiple resistance and pH regulation protein F (MrpF / PhaF)	NA|94aa|down_9|NZ_CP018627.1_2834426_2834708_+	pfam13244, DUF4040, Domain of unknown function (DUF4040)
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	5	2864928-2865079	1,5	PILER-CR,CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GTCGGCCCCGCGCCAGCGGGGGT--------------------------GGTTCC,GTCGGCCCCGCGCCAGCGGGGGTGGTTC	55,28	3	3	2864957-2864989|2864956-2864989|2865018-2865050	NZ_CP018627.1_3809336-3809304|NZ_CP018627.1_3809337-3809304|NZ_CP018627.1_9097555-9097523	NA:NA	2,2	2	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|52aa|up_8|NZ_CP018627.1_2852864_2853020_-,NA|676aa|up_7|NZ_CP018627.1_2853685_2855713_+,NA|148aa|up_2|NZ_CP018627.1_2861971_2862415_+,NA|216aa|down_9|NZ_CP018627.1_2876074_2876722_+	NA|465aa|up_9|NZ_CP018627.1_2850959_2852354_-	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|52aa|up_8|NZ_CP018627.1_2852864_2853020_-	NA	NA|676aa|up_7|NZ_CP018627.1_2853685_2855713_+	NA	NA|212aa|up_6|NZ_CP018627.1_2855760_2856396_-	COG4282, SMI1, Protein involved in beta-1,3-glucan synthesis [Carbohydrate transport and metabolism]	NA|490aa|up_5|NZ_CP018627.1_2857249_2858719_-	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment	NA|371aa|up_4|NZ_CP018627.1_2858845_2859958_-	pfam13683, rve_3, Integrase core domain	NA|256aa|up_3|NZ_CP018627.1_2860129_2860897_-	cd00102, IPT, Immunoglobulin-like fold, Plexins, Transcription factors (IPT)	NA|148aa|up_2|NZ_CP018627.1_2861971_2862415_+	NA	NA|255aa|up_1|NZ_CP018627.1_2862601_2863366_+	pfam13527, Acetyltransf_9, Acetyltransferase (GNAT) domain	NA|292aa|up_0|NZ_CP018627.1_2863415_2864292_-	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096)	NA|340aa|down_0|NZ_CP018627.1_2865354_2866374_+	pfam14224, DUF4331, Domain of unknown function (DUF4331)	NA|405aa|down_1|NZ_CP018627.1_2866440_2867655_-	PRK15072, PRK15072, D-galactonate dehydratase family protein	NA|285aa|down_2|NZ_CP018627.1_2867720_2868575_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|320aa|down_3|NZ_CP018627.1_2868571_2869531_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|436aa|down_4|NZ_CP018627.1_2869530_2870838_-	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|263aa|down_5|NZ_CP018627.1_2871063_2871852_-	COG2186, FadR, Transcriptional regulators [Transcription]	NA|407aa|down_6|NZ_CP018627.1_2872508_2873729_+	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain	NA|188aa|down_7|NZ_CP018627.1_2873993_2874557_-	pfam06821, Ser_hydrolase, Serine hydrolase	NA|252aa|down_8|NZ_CP018627.1_2875000_2875756_+	pfam01636, APH, Phosphotransferase enzyme family	NA|216aa|down_9|NZ_CP018627.1_2876074_2876722_+	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	6	3097548-3097710	6	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CCGCACTCGGCGGAGGCGGCGGCCGGGCCGGACGGCCGGTAGGCGTCAGCGCCCC	55	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|171aa|up_2|NZ_CP018627.1_3094450_3094963_+,NA|73aa|up_1|NZ_CP018627.1_3095215_3095434_-,NA|79aa|up_0|NZ_CP018627.1_3095720_3095957_-,NA|123aa|down_8|NZ_CP018627.1_3110783_3111152_+,NA|135aa|down_9|NZ_CP018627.1_3111267_3111672_+	NA|352aa|up_9|NZ_CP018627.1_3087496_3088552_-	TIGR01824, Anthranilate_synthase_component_I-like_protein, aminodeoxychorismate synthase, component I, clade 2	NA|99aa|up_8|NZ_CP018627.1_3089206_3089503_-	pfam13453, zf-TFIIB, Transcription factor zinc-finger	NA|337aa|up_7|NZ_CP018627.1_3089568_3090579_-	cd05153, HomoserineK_II, Type II Homoserine Kinase	NA|317aa|up_6|NZ_CP018627.1_3090706_3091657_+	pfam04199, Cyclase, Putative cyclase	NA|196aa|up_5|NZ_CP018627.1_3091754_3092342_+	pfam17935, TetR_C_27, Tetracyclin repressor-like, C-terminal domain	NA|155aa|up_4|NZ_CP018627.1_3092385_3092850_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|411aa|up_3|NZ_CP018627.1_3092948_3094181_+	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily	NA|171aa|up_2|NZ_CP018627.1_3094450_3094963_+	NA	NA|73aa|up_1|NZ_CP018627.1_3095215_3095434_-	NA	NA|79aa|up_0|NZ_CP018627.1_3095720_3095957_-	NA	NA|407aa|down_0|NZ_CP018627.1_3098599_3099820_-	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)	NA|1396aa|down_1|NZ_CP018627.1_3099956_3104144_-	pfam02277, DBI_PRT, Phosphoribosyltransferase	NA|418aa|down_2|NZ_CP018627.1_3104424_3105678_-	cd11644, Precorrin-6Y-MT, Precorrin-6Y methyltransferase (also named CbiE)	NA|216aa|down_3|NZ_CP018627.1_3105969_3106617_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|274aa|down_4|NZ_CP018627.1_3106825_3107647_-	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold	NA|263aa|down_5|NZ_CP018627.1_3107743_3108532_-	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]	NA|352aa|down_6|NZ_CP018627.1_3108528_3109584_-	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional	NA|216aa|down_7|NZ_CP018627.1_3109987_3110635_-	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p)	NA|123aa|down_8|NZ_CP018627.1_3110783_3111152_+	NA	NA|135aa|down_9|NZ_CP018627.1_3111267_3111672_+	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	7	3101777-3102011	7	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CGGGCCCGGCGGCTGCGGGCTCGG	24	1	1	3101960-3101986	NZ_CP018627.1_3101990-3102016	NA	4	4	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|171aa|up_5|NZ_CP018627.1_3094450_3094963_+,NA|73aa|up_4|NZ_CP018627.1_3095215_3095434_-,NA|79aa|up_3|NZ_CP018627.1_3095720_3095957_-,NA|123aa|down_6|NZ_CP018627.1_3110783_3111152_+,NA|135aa|down_7|NZ_CP018627.1_3111267_3111672_+	NA|317aa|up_9|NZ_CP018627.1_3090706_3091657_+	pfam04199, Cyclase, Putative cyclase	NA|196aa|up_8|NZ_CP018627.1_3091754_3092342_+	pfam17935, TetR_C_27, Tetracyclin repressor-like, C-terminal domain	NA|155aa|up_7|NZ_CP018627.1_3092385_3092850_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|411aa|up_6|NZ_CP018627.1_3092948_3094181_+	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily	NA|171aa|up_5|NZ_CP018627.1_3094450_3094963_+	NA	NA|73aa|up_4|NZ_CP018627.1_3095215_3095434_-	NA	NA|79aa|up_3|NZ_CP018627.1_3095720_3095957_-	NA	NA|442aa|up_2|NZ_CP018627.1_3096263_3097589_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|273aa|up_1|NZ_CP018627.1_3097700_3098519_-	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis]	NA|407aa|up_0|NZ_CP018627.1_3098599_3099820_-	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)	NA|418aa|down_0|NZ_CP018627.1_3104424_3105678_-	cd11644, Precorrin-6Y-MT, Precorrin-6Y methyltransferase (also named CbiE)	NA|216aa|down_1|NZ_CP018627.1_3105969_3106617_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|274aa|down_2|NZ_CP018627.1_3106825_3107647_-	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold	NA|263aa|down_3|NZ_CP018627.1_3107743_3108532_-	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]	NA|352aa|down_4|NZ_CP018627.1_3108528_3109584_-	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional	NA|216aa|down_5|NZ_CP018627.1_3109987_3110635_-	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p)	NA|123aa|down_6|NZ_CP018627.1_3110783_3111152_+	NA	NA|135aa|down_7|NZ_CP018627.1_3111267_3111672_+	NA	NA|168aa|down_8|NZ_CP018627.1_3111770_3112274_-	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain	NA|174aa|down_9|NZ_CP018627.1_3112395_3112917_-	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	8	3102107-3102316	8	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CGGGCCCGGCGGCTGCGGGCTCGG	24	0	0	NA	NA	NA	3	3	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|171aa|up_5|NZ_CP018627.1_3094450_3094963_+,NA|73aa|up_4|NZ_CP018627.1_3095215_3095434_-,NA|79aa|up_3|NZ_CP018627.1_3095720_3095957_-,NA|123aa|down_6|NZ_CP018627.1_3110783_3111152_+,NA|135aa|down_7|NZ_CP018627.1_3111267_3111672_+	NA|317aa|up_9|NZ_CP018627.1_3090706_3091657_+	pfam04199, Cyclase, Putative cyclase	NA|196aa|up_8|NZ_CP018627.1_3091754_3092342_+	pfam17935, TetR_C_27, Tetracyclin repressor-like, C-terminal domain	NA|155aa|up_7|NZ_CP018627.1_3092385_3092850_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|411aa|up_6|NZ_CP018627.1_3092948_3094181_+	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily	NA|171aa|up_5|NZ_CP018627.1_3094450_3094963_+	NA	NA|73aa|up_4|NZ_CP018627.1_3095215_3095434_-	NA	NA|79aa|up_3|NZ_CP018627.1_3095720_3095957_-	NA	NA|442aa|up_2|NZ_CP018627.1_3096263_3097589_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|273aa|up_1|NZ_CP018627.1_3097700_3098519_-	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis]	NA|407aa|up_0|NZ_CP018627.1_3098599_3099820_-	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT)	NA|418aa|down_0|NZ_CP018627.1_3104424_3105678_-	cd11644, Precorrin-6Y-MT, Precorrin-6Y methyltransferase (also named CbiE)	NA|216aa|down_1|NZ_CP018627.1_3105969_3106617_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|274aa|down_2|NZ_CP018627.1_3106825_3107647_-	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold	NA|263aa|down_3|NZ_CP018627.1_3107743_3108532_-	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]	NA|352aa|down_4|NZ_CP018627.1_3108528_3109584_-	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional	NA|216aa|down_5|NZ_CP018627.1_3109987_3110635_-	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p)	NA|123aa|down_6|NZ_CP018627.1_3110783_3111152_+	NA	NA|135aa|down_7|NZ_CP018627.1_3111267_3111672_+	NA	NA|168aa|down_8|NZ_CP018627.1_3111770_3112274_-	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain	NA|174aa|down_9|NZ_CP018627.1_3112395_3112917_-	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	9	3271024-3271148	9	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GCCCCTGGCAACGCAATCCAGCCCCTCCGGCGATTGAGGAGC	42	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|348aa|up_8|NZ_CP018627.1_3254621_3255665_-,NA	NA|804aa|up_9|NZ_CP018627.1_3251602_3254014_+	COG2183, Tex, Transcriptional accessory protein [Transcription]	NA|348aa|up_8|NZ_CP018627.1_3254621_3255665_-	NA	NA|597aa|up_7|NZ_CP018627.1_3255864_3257655_-	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter	NA|441aa|up_6|NZ_CP018627.1_3257769_3259092_-	cd06242, M14-like, Peptidase M14-like domain; uncharacterized subgroup	NA|497aa|up_5|NZ_CP018627.1_3261454_3262945_+	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain	NA|287aa|up_4|NZ_CP018627.1_3263027_3263888_-	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236)	NA|1247aa|up_3|NZ_CP018627.1_3263907_3267648_-	PRK09525, lacZ, beta-galactosidase	NA|248aa|up_2|NZ_CP018627.1_3267922_3268666_+	cd04778, HTH_MerR-like_sg2, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily	NA|299aa|up_1|NZ_CP018627.1_3268923_3269820_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|313aa|up_0|NZ_CP018627.1_3269941_3270880_+	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold	NA|763aa|down_0|NZ_CP018627.1_3271299_3273588_-	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ	NA|405aa|down_1|NZ_CP018627.1_3273860_3275075_-	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|387aa|down_2|NZ_CP018627.1_3275153_3276314_-	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]	NA|486aa|down_3|NZ_CP018627.1_3276489_3277947_-	PRK03893, PRK03893, putative sialic acid transporter; Provisional	NA|313aa|down_4|NZ_CP018627.1_3277943_3278882_-	cd00408, DHDPS-like, Dihydrodipicolinate synthase family	NA|202aa|down_5|NZ_CP018627.1_3278931_3279537_+	pfam06718, DUF1203, Protein of unknown function (DUF1203)	NA|247aa|down_6|NZ_CP018627.1_3279693_3280434_-	pfam04493, Endonuclease_5, Endonuclease V	NA|99aa|down_7|NZ_CP018627.1_3280464_3280761_+	COG2350, COG2350, Uncharacterized protein conserved in bacteria [Function unknown]	NA|361aa|down_8|NZ_CP018627.1_3280788_3281871_-	COG4447, COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]	NA|494aa|down_9|NZ_CP018627.1_3282205_3283687_-	pfam08601, PAP1, Transcription factor PAP1
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	10	4155329-4155421	10	CRISPRCasFinder	no	DEDDh	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Unclear	CACGGCCTGACGAGCGCCGGTTGCGGCCCG	30	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|79aa|up_4|NZ_CP018627.1_4149209_4149446_+,NA|304aa|down_1|NZ_CP018627.1_4157153_4158065_+,NA|78aa|down_3|NZ_CP018627.1_4159216_4159450_+,NA|239aa|down_8|NZ_CP018627.1_4164276_4164993_-	NA|514aa|up_9|NZ_CP018627.1_4143480_4145022_+	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]	NA|465aa|up_8|NZ_CP018627.1_4145110_4146505_+	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]	NA|473aa|up_7|NZ_CP018627.1_4146572_4147991_+	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated	NA|97aa|up_6|NZ_CP018627.1_4148107_4148398_-	COG2261, COG2261, Predicted membrane protein [Function unknown]	NA|130aa|up_5|NZ_CP018627.1_4148626_4149016_+	pfam11298, DUF3099, Protein of unknown function (DUF3099)	NA|79aa|up_4|NZ_CP018627.1_4149209_4149446_+	NA	NA|330aa|up_3|NZ_CP018627.1_4149488_4150478_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|540aa|up_2|NZ_CP018627.1_4150582_4152202_-	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain	NA|119aa|up_1|NZ_CP018627.1_4152198_4152555_-	pfam04341, DUF485, Protein of unknown function, DUF485	NA|493aa|up_0|NZ_CP018627.1_4153245_4154724_+	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins	NA|317aa|down_0|NZ_CP018627.1_4156082_4157033_-	COG3000, ERG3, Sterol desaturase [Lipid metabolism]	NA|304aa|down_1|NZ_CP018627.1_4157153_4158065_+	NA	DEDDh|329aa|down_2|NZ_CP018627.1_4158166_4159153_+	PRK06063, PRK06063, DEDDh family exonuclease	NA|78aa|down_3|NZ_CP018627.1_4159216_4159450_+	NA	NA|270aa|down_4|NZ_CP018627.1_4159528_4160338_+	cd06662, SURF1, SURF1 superfamily	NA|594aa|down_5|NZ_CP018627.1_4160385_4162167_+	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]	NA|252aa|down_6|NZ_CP018627.1_4162171_4162927_+	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR	NA|185aa|down_7|NZ_CP018627.1_4163714_4164269_-	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP	NA|239aa|down_8|NZ_CP018627.1_4164276_4164993_-	NA	NA|151aa|down_9|NZ_CP018627.1_4164989_4165442_-	pfam03780, Asp23, Asp23 family, cell envelope-related function
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	11	4539398-4539490	11	CRISPRCasFinder	no	WYL,csa3	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Type I-A	CCCCGCCACCTGACCAGCGACCG	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|124aa|up_2|NZ_CP018627.1_4535780_4536152_-,NA|66aa|down_3|NZ_CP018627.1_4543873_4544071_+	NA|892aa|up_9|NZ_CP018627.1_4526169_4528845_+	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed	WYL|322aa|up_8|NZ_CP018627.1_4529473_4530439_+	COG2378, COG2378, Predicted transcriptional regulator [Transcription]	NA|309aa|up_7|NZ_CP018627.1_4530731_4531658_-	PRK08303, PRK08303, short chain dehydrogenase; Provisional	NA|173aa|up_6|NZ_CP018627.1_4531867_4532386_+	pfam14024, DUF4240, Protein of unknown function (DUF4240)	NA|162aa|up_5|NZ_CP018627.1_4532445_4532931_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|300aa|up_4|NZ_CP018627.1_4533089_4533989_+	TIGR01777, Hypothetical_UPF0105_protein_Rv2216/MT2273/Mb2239	NA|449aa|up_3|NZ_CP018627.1_4534227_4535574_+	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase	NA|124aa|up_2|NZ_CP018627.1_4535780_4536152_-	NA	NA|483aa|up_1|NZ_CP018627.1_4536168_4537617_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	csa3|254aa|up_0|NZ_CP018627.1_4538377_4539139_+	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors	NA|548aa|down_0|NZ_CP018627.1_4539681_4541325_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|258aa|down_1|NZ_CP018627.1_4541580_4542354_+	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB	NA|317aa|down_2|NZ_CP018627.1_4542676_4543627_+	PRK05481, PRK05481, lipoyl synthase; Provisional	NA|66aa|down_3|NZ_CP018627.1_4543873_4544071_+	NA	NA|227aa|down_4|NZ_CP018627.1_4544081_4544762_+	pfam13829, DUF4191, Domain of unknown function (DUF4191)	NA|156aa|down_5|NZ_CP018627.1_4544873_4545341_-	pfam06271, RDD, RDD family	NA|470aa|down_6|NZ_CP018627.1_4545595_4547005_+	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I	NA|197aa|down_7|NZ_CP018627.1_4547079_4547670_-	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3)	NA|456aa|down_8|NZ_CP018627.1_4548030_4549398_-	PTZ00146, PTZ00146, fibrillarin; Provisional	NA|213aa|down_9|NZ_CP018627.1_4549527_4550166_-	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3)
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	12	4609822-4610077	2,12	PILER-CR,CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CCCGGGGCGAAGCCCCCGCCGGGGTCTGGGGCGGAGCCCCAGTTTCGGGAAGGGGCG,CCGGGGTCTGGGGCGGAGCCCCAGTTTCGGGAAGGGGCGGGGAGGGGA	57,48	0	0	NA	NA	NA:NA	2,1	2	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|107aa|up_7|NZ_CP018627.1_4596352_4596673_+,NA|368aa|up_6|NZ_CP018627.1_4596756_4597860_+,NA|67aa|down_9|NZ_CP018627.1_4622836_4623037_-	NA|298aa|up_9|NZ_CP018627.1_4594657_4595551_-	pfam13560, HTH_31, Helix-turn-helix domain	NA|143aa|up_8|NZ_CP018627.1_4595725_4596154_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|107aa|up_7|NZ_CP018627.1_4596352_4596673_+	NA	NA|368aa|up_6|NZ_CP018627.1_4596756_4597860_+	NA	NA|1086aa|up_5|NZ_CP018627.1_4599230_4602488_-	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	NA|209aa|up_4|NZ_CP018627.1_4602607_4603234_-	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083	NA|454aa|up_3|NZ_CP018627.1_4603321_4604683_-	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism]	NA|548aa|up_2|NZ_CP018627.1_4605107_4606751_+	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]	NA|585aa|up_1|NZ_CP018627.1_4606890_4608645_+	PRK13981, PRK13981, NAD synthetase; Provisional	NA|259aa|up_0|NZ_CP018627.1_4608702_4609479_-	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|402aa|down_0|NZ_CP018627.1_4610100_4611306_-	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|342aa|down_1|NZ_CP018627.1_4611530_4612556_-	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2	NA|203aa|down_2|NZ_CP018627.1_4612728_4613337_-	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|542aa|down_3|NZ_CP018627.1_4613333_4614959_-	PRK14995, PRK14995, SmvA family efflux MFS transporter	NA|287aa|down_4|NZ_CP018627.1_4615179_4616040_+	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed	NA|337aa|down_5|NZ_CP018627.1_4616273_4617284_+	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit	NA|270aa|down_6|NZ_CP018627.1_4617295_4618105_+	pfam01061, ABC2_membrane, ABC-2 type transporter	NA|1137aa|down_7|NZ_CP018627.1_4618211_4621622_-	COG3903, COG3903, Predicted ATPase [General function prediction only]	NA|266aa|down_8|NZ_CP018627.1_4621843_4622641_+	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms	NA|67aa|down_9|NZ_CP018627.1_4622836_4623037_-	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	13	4680630-4680781	13,3	CRISPRCasFinder,PILER-CR	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CGGGACCATCCCCGCGGGCGCGGGGAGCAG,CCCGCGGGGAT--------------------------GGTCCC	30,43	0	0	NA	NA	I-E:NA	2,2	2	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|134aa|up_0|NZ_CP018627.1_4679513_4679915_+,NA	NA|144aa|up_9|NZ_CP018627.1_4669924_4670356_+	pfam10025, DUF2267, Uncharacterized conserved protein (DUF2267)	NA|257aa|up_8|NZ_CP018627.1_4670426_4671197_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|289aa|up_7|NZ_CP018627.1_4671200_4672067_-	PRK06224, PRK06224, citryl-CoA lyase	NA|430aa|up_6|NZ_CP018627.1_4672168_4673458_-	pfam02515, CoA_transf_3, CoA-transferase family III	NA|461aa|up_5|NZ_CP018627.1_4673528_4674911_+	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily	NA|301aa|up_4|NZ_CP018627.1_4674964_4675867_-	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|293aa|up_3|NZ_CP018627.1_4676015_4676894_+	COG0583, LysR, Transcriptional regulator [Transcription]	NA|357aa|up_2|NZ_CP018627.1_4677049_4678120_+	PRK08194, PRK08194, tartrate dehydrogenase; Provisional	NA|411aa|up_1|NZ_CP018627.1_4678243_4679476_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|134aa|up_0|NZ_CP018627.1_4679513_4679915_+	NA	NA|192aa|down_0|NZ_CP018627.1_4681549_4682125_-	pfam05685, Uma2, Putative restriction endonuclease	NA|268aa|down_1|NZ_CP018627.1_4682658_4683462_+	PRK02101, PRK02101, peroxide stress protein YaaA	NA|220aa|down_2|NZ_CP018627.1_4683721_4684381_+	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional	NA|401aa|down_3|NZ_CP018627.1_4684427_4685630_-	PRK07238, PRK07238, bifunctional RNase H/acid phosphatase; Provisional	NA|248aa|down_4|NZ_CP018627.1_4685634_4686378_-	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]	NA|287aa|down_5|NZ_CP018627.1_4686506_4687367_-	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3)	NA|345aa|down_6|NZ_CP018627.1_4687503_4688538_-	cd01146, FhuD, Fe3+-siderophore binding domain FhuD	NA|315aa|down_7|NZ_CP018627.1_4691503_4692448_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|362aa|down_8|NZ_CP018627.1_4692486_4693572_-	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase	NA|285aa|down_9|NZ_CP018627.1_4693696_4694551_-	PLN02864, PLN02864, enoyl-CoA hydratase
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	14	4874437-4874540	14	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	TGCTCTGCCAATTGAGCTACAGGGGA	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|310aa|up_3|NZ_CP018627.1_4870953_4871883_-,NA|75aa|up_0|NZ_CP018627.1_4873764_4873989_+,NA|90aa|down_0|NZ_CP018627.1_4874787_4875057_+	NA|148aa|up_9|NZ_CP018627.1_4862520_4862964_-	cd14505, CDKN3-like, cyclin-dependent kinase inhibitor 3 and similar proteins	NA|147aa|up_8|NZ_CP018627.1_4863155_4863596_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|912aa|up_7|NZ_CP018627.1_4863634_4866370_-	pfam08305, NPCBM, NPCBM/NEW2 domain	NA|493aa|up_6|NZ_CP018627.1_4866532_4868011_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|227aa|up_5|NZ_CP018627.1_4867997_4868678_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|513aa|up_4|NZ_CP018627.1_4868806_4870345_+	COG5305, COG5305, Predicted membrane protein [Function unknown]	NA|310aa|up_3|NZ_CP018627.1_4870953_4871883_-	NA	NA|319aa|up_2|NZ_CP018627.1_4871972_4872929_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|149aa|up_1|NZ_CP018627.1_4872925_4873372_-	COG1725, COG1725, Predicted transcriptional regulators [Transcription]	NA|75aa|up_0|NZ_CP018627.1_4873764_4873989_+	NA	NA|90aa|down_0|NZ_CP018627.1_4874787_4875057_+	NA	NA|529aa|down_1|NZ_CP018627.1_4875082_4876669_+	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases	NA|415aa|down_2|NZ_CP018627.1_4876923_4878168_-	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|672aa|down_3|NZ_CP018627.1_4878510_4880526_-	PRK05667, dnaG, DNA primase; Validated	NA|432aa|down_4|NZ_CP018627.1_4880601_4881897_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|454aa|down_5|NZ_CP018627.1_4882197_4883559_-	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional	NA|347aa|down_6|NZ_CP018627.1_4883555_4884596_-	pfam01903, CbiX, CbiX	NA|763aa|down_7|NZ_CP018627.1_4884840_4887129_+	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite	NA|329aa|down_8|NZ_CP018627.1_4887169_4888156_-	PRK09358, PRK09358, adenosine deaminase; Provisional	NA|216aa|down_9|NZ_CP018627.1_4888323_4888971_+	cd06260, DUF820, Domain of unknown function (DUF820)
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	15	5251793-5251878	15	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GTCCTCAAGCGCCGGACGGGCTT	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA,NA|189aa|down_9|NZ_CP018627.1_5382879_5383446_-	NA|312aa|up_9|NZ_CP018627.1_5224812_5225748_-	PRK11242, PRK11242, DNA-binding transcriptional regulator CynR; Provisional	NA|348aa|up_8|NZ_CP018627.1_5225922_5226966_-	pfam13469, Sulfotransfer_3, Sulfotransferase family	NA|937aa|up_7|NZ_CP018627.1_5227604_5230415_+	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|553aa|up_6|NZ_CP018627.1_5230454_5232113_+	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase	NA|470aa|up_5|NZ_CP018627.1_5232206_5233616_-	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|219aa|up_4|NZ_CP018627.1_5233686_5234343_-	pfam00975, Thioesterase, Thioesterase domain	NA|335aa|up_3|NZ_CP018627.1_5234695_5235700_+	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|252aa|up_2|NZ_CP018627.1_5236368_5237124_+	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms]	NA|313aa|up_1|NZ_CP018627.1_5237158_5238097_+	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]	NA|3921aa|up_0|NZ_CP018627.1_5238209_5249972_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|3206aa|down_0|NZ_CP018627.1_5267349_5276967_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|7198aa|down_1|NZ_CP018627.1_5277023_5298617_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|5202aa|down_2|NZ_CP018627.1_5298668_5314274_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|1659aa|down_3|NZ_CP018627.1_5314535_5319512_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|8608aa|down_4|NZ_CP018627.1_5319576_5345400_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|3435aa|down_5|NZ_CP018627.1_5345425_5355730_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|8216aa|down_6|NZ_CP018627.1_5355777_5380425_-	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]	NA|516aa|down_7|NZ_CP018627.1_5380758_5382306_-	COG3428, COG3428, Predicted membrane protein [Function unknown]	NA|167aa|down_8|NZ_CP018627.1_5382302_5382803_-	COG3402, COG3402, Uncharacterized conserved protein [Function unknown]	NA|189aa|down_9|NZ_CP018627.1_5382879_5383446_-	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	16	6035929-6036026	16	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GCACCTCCCGGCGGTAGCCGGGG	23	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|119aa|up_7|NZ_CP018627.1_6028179_6028536_-,NA|49aa|up_5|NZ_CP018627.1_6030553_6030700_+,NA|72aa|up_2|NZ_CP018627.1_6032960_6033176_-,NA	NA|367aa|up_9|NZ_CP018627.1_6024965_6026066_-	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|700aa|up_8|NZ_CP018627.1_6026083_6028183_-	COG1215, COG1215, Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]	NA|119aa|up_7|NZ_CP018627.1_6028179_6028536_-	NA	NA|472aa|up_6|NZ_CP018627.1_6029006_6030422_-	PRK06061, PRK06061, amidase; Provisional	NA|49aa|up_5|NZ_CP018627.1_6030553_6030700_+	NA	NA|417aa|up_4|NZ_CP018627.1_6030755_6032006_-	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II	NA|238aa|up_3|NZ_CP018627.1_6032127_6032841_+	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]	NA|72aa|up_2|NZ_CP018627.1_6032960_6033176_-	NA	NA|530aa|up_1|NZ_CP018627.1_6033286_6034876_-	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM	NA|299aa|up_0|NZ_CP018627.1_6035011_6035908_+	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|392aa|down_0|NZ_CP018627.1_6036340_6037516_-	PHA00370, III, attachment protein	NA|228aa|down_1|NZ_CP018627.1_6037515_6038199_-	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]	NA|357aa|down_2|NZ_CP018627.1_6038259_6039330_-	pfam14219, DUF4328, Domain of unknown function (DUF4328)	NA|557aa|down_3|NZ_CP018627.1_6039659_6041330_-	cd06564, GH20_DspB_LnbB-like, Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins	NA|184aa|down_4|NZ_CP018627.1_6041646_6042198_+	PRK13798, PRK13798, putative OHCU decarboxylase; Provisional	NA|127aa|down_5|NZ_CP018627.1_6042354_6042735_+	cd03501, SQR_TypeA_SdhC_like, Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase C (SdhC)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol	NA|157aa|down_6|NZ_CP018627.1_6042740_6043211_+	cd03500, SQR_TypeA_SdhD_like, Succinate:quinone oxidoreductase (SQR) Type A subfamily, Succinate dehydrogenase D (SdhD)-like subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol	NA|585aa|down_7|NZ_CP018627.1_6043235_6044990_+	PRK08205, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed	NA|258aa|down_8|NZ_CP018627.1_6044989_6045763_+	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed	NA|465aa|down_9|NZ_CP018627.1_6045930_6047325_+	pfam04892, VanZ, VanZ like family
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	17	6169568-6169699	17	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	TCACGGGTTCCTCACTCACATCCGGAAGACGCCGAAGC	38	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA,NA|528aa|down_3|NZ_CP018627.1_6176499_6178083_-,NA|175aa|down_9|NZ_CP018627.1_6185268_6185793_+	NA|290aa|up_9|NZ_CP018627.1_6155371_6156241_-	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|231aa|up_8|NZ_CP018627.1_6157052_6157745_-	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription]	NA|252aa|up_7|NZ_CP018627.1_6157897_6158653_+	PRK02947, PRK02947, sugar isomerase domain-containing protein	NA|517aa|up_6|NZ_CP018627.1_6158743_6160294_-	pfam00989, PAS, PAS fold	NA|232aa|up_5|NZ_CP018627.1_6160783_6161479_-	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase	NA|367aa|up_4|NZ_CP018627.1_6161819_6162920_+	PRK12350, PRK12350, citrate synthase 2; Provisional	NA|212aa|up_3|NZ_CP018627.1_6163018_6163654_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|316aa|up_2|NZ_CP018627.1_6163650_6164598_-	PRK07827, PRK07827, enoyl-CoA hydratase family protein	NA|528aa|up_1|NZ_CP018627.1_6164594_6166178_-	cd05904, 4CL, 4-Coumarate-CoA Ligase (4CL)	NA|387aa|up_0|NZ_CP018627.1_6166339_6167500_-	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|571aa|down_0|NZ_CP018627.1_6171354_6173067_-	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA	NA|287aa|down_1|NZ_CP018627.1_6173063_6173924_-	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein	NA|801aa|down_2|NZ_CP018627.1_6174100_6176503_-	sd00006, TPR, Tetratricopeptide repeat	NA|528aa|down_3|NZ_CP018627.1_6176499_6178083_-	NA	NA|142aa|down_4|NZ_CP018627.1_6178215_6178641_-	pfam18478, PIN_10, PIN like domain	NA|219aa|down_5|NZ_CP018627.1_6178591_6179248_-	pfam04255, DUF433, Protein of unknown function (DUF433)	NA|941aa|down_6|NZ_CP018627.1_6179450_6182273_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|373aa|down_7|NZ_CP018627.1_6182451_6183570_+	TIGR01366, Putative_phosphoserine_aminotransferase_PSAT	NA|337aa|down_8|NZ_CP018627.1_6183787_6184798_-	pfam13449, Phytase-like, Esterase-like activity of phytase	NA|175aa|down_9|NZ_CP018627.1_6185268_6185793_+	NA
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	18	6223308-6223398	18	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GGCCACACCGCCCGCGCGGGGCACTCACCT	30	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|143aa|up_6|NZ_CP018627.1_6216018_6216447_+,NA|122aa|down_1|NZ_CP018627.1_6223850_6224216_-	NA|965aa|up_9|NZ_CP018627.1_6210052_6212947_+	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|157aa|up_8|NZ_CP018627.1_6213040_6213511_-	pfam04892, VanZ, VanZ like family	NA|550aa|up_7|NZ_CP018627.1_6214202_6215852_+	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|143aa|up_6|NZ_CP018627.1_6216018_6216447_+	NA	NA|711aa|up_5|NZ_CP018627.1_6216752_6218885_+	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only]	NA|140aa|up_4|NZ_CP018627.1_6218929_6219349_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|243aa|up_3|NZ_CP018627.1_6219594_6220323_-	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]	NA|224aa|up_2|NZ_CP018627.1_6220379_6221051_+	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown]	NA|223aa|up_1|NZ_CP018627.1_6221151_6221820_-	pfam03575, Peptidase_S51, Peptidase family S51	NA|413aa|up_0|NZ_CP018627.1_6222042_6223281_+	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism]	NA|91aa|down_0|NZ_CP018627.1_6223578_6223851_-	pfam13223, DUF4031, Protein of unknown function (DUF4031)	NA|122aa|down_1|NZ_CP018627.1_6223850_6224216_-	NA	NA|313aa|down_2|NZ_CP018627.1_6224320_6225259_+	COG1737, RpiR, Transcriptional regulators [Transcription]	NA|324aa|down_3|NZ_CP018627.1_6225376_6226348_+	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed	NA|542aa|down_4|NZ_CP018627.1_6226496_6228122_-	PRK00013, groEL, chaperonin GroEL; Reviewed	NA|69aa|down_5|NZ_CP018627.1_6228541_6228748_-	COG1278, CspC, Cold shock proteins [Transcription]	NA|93aa|down_6|NZ_CP018627.1_6229157_6229436_-	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins	NA|434aa|down_7|NZ_CP018627.1_6229432_6230734_-	PRK07591, PRK07591, threonine synthase; Validated	NA|316aa|down_8|NZ_CP018627.1_6231086_6232034_+	PRK13915, PRK13915, putative glucosyl-3-phosphoglycerate synthase; Provisional	NA|489aa|down_9|NZ_CP018627.1_6232149_6233616_+	cd03788, GT20_TPS, trehalose-6-phosphate synthase
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	19	7255565-7255649	19	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GCTCAGCGCTCGCGAACGGGCTCAGC	26	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|234aa|up_5|NZ_CP018627.1_7249266_7249968_-,NA|145aa|down_4|NZ_CP018627.1_7259014_7259449_-	NA|499aa|up_9|NZ_CP018627.1_7242366_7243863_+	pfam08386, Abhydrolase_4, TAP-like protein	NA|596aa|up_8|NZ_CP018627.1_7243956_7245744_-	PLN02286, PLN02286, arginine-tRNA ligase	NA|584aa|up_7|NZ_CP018627.1_7245900_7247652_+	PRK00750, lysK, lysyl-tRNA synthetase; Reviewed	NA|489aa|up_6|NZ_CP018627.1_7247711_7249178_-	pfam10935, DUF2637, Protein of unknown function (DUF2637)	NA|234aa|up_5|NZ_CP018627.1_7249266_7249968_-	NA	NA|293aa|up_4|NZ_CP018627.1_7250103_7250982_-	pfam10220, Smg8_Smg9, Smg8_Smg9	NA|398aa|up_3|NZ_CP018627.1_7251199_7252393_+	pfam01139, RtcB, tRNA-splicing ligase RtcB	NA|413aa|up_2|NZ_CP018627.1_7252503_7253742_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|469aa|up_1|NZ_CP018627.1_7253806_7255213_-	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional	NA|79aa|up_0|NZ_CP018627.1_7255202_7255439_-	pfam13370, Fer4_13, 4Fe-4S single cluster domain of Ferredoxin I	NA|252aa|down_0|NZ_CP018627.1_7255663_7256419_-	cd05346, SDR_c5, classical (c) SDR, subgroup 5	NA|442aa|down_1|NZ_CP018627.1_7256674_7258000_+	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|111aa|down_2|NZ_CP018627.1_7257989_7258322_-	PRK02237, PRK02237, YnfA family protein	NA|179aa|down_3|NZ_CP018627.1_7258438_7258975_+	pfam12867, DinB_2, DinB superfamily	NA|145aa|down_4|NZ_CP018627.1_7259014_7259449_-	NA	NA|439aa|down_5|NZ_CP018627.1_7259682_7260999_+	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase	NA|233aa|down_6|NZ_CP018627.1_7260995_7261694_+	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1)	NA|395aa|down_7|NZ_CP018627.1_7261960_7263145_+	cd10976, CE4_CDA_like_3, Putative catalytic domain of uncharacterized bacterial hypothetical proteins similar to insect chitin deacetylase-like proteins	NA|206aa|down_8|NZ_CP018627.1_7263251_7263869_+	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|255aa|down_9|NZ_CP018627.1_7263874_7264639_+	pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	20	7747522-7747617	20	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	GAGGACGACTGGCCGTCGGCCGGTGGG	27	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|173aa|up_9|NZ_CP018627.1_7737250_7737769_-,NA|287aa|up_4|NZ_CP018627.1_7742038_7742899_-,NA	NA|173aa|up_9|NZ_CP018627.1_7737250_7737769_-	NA	NA|197aa|up_8|NZ_CP018627.1_7737839_7738430_-	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional	NA|200aa|up_7|NZ_CP018627.1_7738514_7739114_-	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed	NA|326aa|up_6|NZ_CP018627.1_7739314_7740292_-	PRK03092, PRK03092, ribose-phosphate diphosphokinase	NA|486aa|up_5|NZ_CP018627.1_7740363_7741821_-	PRK14352, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	NA|287aa|up_4|NZ_CP018627.1_7742038_7742899_-	NA	NA|528aa|up_3|NZ_CP018627.1_7743088_7744672_+	cd16917, HATPase_UhpB-NarQ-NarX-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ	NA|163aa|up_2|NZ_CP018627.1_7744708_7745197_-	pfam14433, SUKH-3, SUKH-3 immunity protein	NA|174aa|up_1|NZ_CP018627.1_7745277_7745799_-	pfam14431, YwqJ-deaminase, YwqJ-like deaminase	NA|326aa|up_0|NZ_CP018627.1_7745995_7746973_+	pfam14414, WHH, A nuclease of the HNH/ENDO VII superfamily with conserved WHH	NA|307aa|down_0|NZ_CP018627.1_7750420_7751341_+	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown]	NA|529aa|down_1|NZ_CP018627.1_7751489_7753076_-	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|263aa|down_2|NZ_CP018627.1_7753520_7754309_+	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|857aa|down_3|NZ_CP018627.1_7754305_7756876_+	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]	NA|336aa|down_4|NZ_CP018627.1_7757021_7758029_-	cd08292, ETR_like_2, 2-enoyl thioester reductase (ETR) like proteins, child 2	NA|329aa|down_5|NZ_CP018627.1_7758891_7759878_+	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR)	NA|391aa|down_6|NZ_CP018627.1_7759947_7761120_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|333aa|down_7|NZ_CP018627.1_7761536_7762535_-	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]	NA|124aa|down_8|NZ_CP018627.1_7762537_7762909_-	cd06587, VOC, vicinal oxygen chelate (VOC) family	NA|154aa|down_9|NZ_CP018627.1_7762991_7763453_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	21	7811278-7811372	21	CRISPRCasFinder	no	WYL	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Unclear	TGCCGCCGAGGCCGCAGTAGCCGG	24	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|227aa|up_7|NZ_CP018627.1_7802047_7802728_-,NA|69aa|up_2|NZ_CP018627.1_7808769_7808976_-,NA|366aa|down_0|NZ_CP018627.1_7812065_7813163_-,NA|85aa|down_2|NZ_CP018627.1_7814633_7814888_-	NA|269aa|up_9|NZ_CP018627.1_7800225_7801032_+	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator	NA|336aa|up_8|NZ_CP018627.1_7801028_7802036_+	pfam16169, DUF4872, Domain of unknown function (DUF4872)	NA|227aa|up_7|NZ_CP018627.1_7802047_7802728_-	NA	NA|250aa|up_6|NZ_CP018627.1_7802962_7803712_-	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus	NA|164aa|up_5|NZ_CP018627.1_7805073_7805565_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|358aa|up_4|NZ_CP018627.1_7805650_7806724_-	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only]	NA|555aa|up_3|NZ_CP018627.1_7806720_7808385_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|69aa|up_2|NZ_CP018627.1_7808769_7808976_-	NA	NA|112aa|up_1|NZ_CP018627.1_7808987_7809323_-	pfam07110, EthD, EthD domain	NA|128aa|up_0|NZ_CP018627.1_7809467_7809851_+	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily	NA|366aa|down_0|NZ_CP018627.1_7812065_7813163_-	NA	NA|388aa|down_1|NZ_CP018627.1_7813300_7814464_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|85aa|down_2|NZ_CP018627.1_7814633_7814888_-	NA	NA|161aa|down_3|NZ_CP018627.1_7815682_7816165_-	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|402aa|down_4|NZ_CP018627.1_7816669_7817875_+	PRK08198, PRK08198, threonine dehydratase; Provisional	NA|329aa|down_5|NZ_CP018627.1_7818112_7819099_+	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit	NA|288aa|down_6|NZ_CP018627.1_7819098_7819962_+	pfam01061, ABC2_membrane, ABC-2 type transporter	NA|166aa|down_7|NZ_CP018627.1_7820095_7820593_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|135aa|down_8|NZ_CP018627.1_7820780_7821185_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|291aa|down_9|NZ_CP018627.1_7821282_7822155_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	22	10170870-10170962	22	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CGGTCCCGAGCCTTCGCCGGTGA	23	1	1	10170893-10170939	NZ_CP018627.1_10170858-10170904	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA,NA|81aa|down_3|NZ_CP018627.1_10174059_10174302_-	NA|354aa|up_9|NZ_CP018627.1_10158813_10159875_-	COG1609, PurR, Transcriptional regulators [Transcription]	NA|326aa|up_8|NZ_CP018627.1_10160020_10160998_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|56aa|up_7|NZ_CP018627.1_10161089_10161257_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|686aa|up_6|NZ_CP018627.1_10161326_10163384_-	cd14792, GH27, glycosyl hydrolase family 27 (GH27)	NA|419aa|up_5|NZ_CP018627.1_10163624_10164881_+	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]	NA|305aa|up_4|NZ_CP018627.1_10164893_10165808_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|306aa|up_3|NZ_CP018627.1_10165804_10166722_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|345aa|up_2|NZ_CP018627.1_10166927_10167962_+	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|454aa|up_1|NZ_CP018627.1_10168089_10169451_-	PRK07907, PRK07907, hypothetical protein; Provisional	NA|402aa|up_0|NZ_CP018627.1_10169620_10170826_+	TIGR02032, Uncharacterized_protein_MJ1520, geranylgeranyl reductase family	NA|410aa|down_0|NZ_CP018627.1_10171110_10172340_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|222aa|down_1|NZ_CP018627.1_10172363_10173029_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|302aa|down_2|NZ_CP018627.1_10173154_10174060_-	pfam10977, DUF2797, Protein of unknown function (DUF2797)	NA|81aa|down_3|NZ_CP018627.1_10174059_10174302_-	NA	NA|170aa|down_4|NZ_CP018627.1_10174308_10174818_-	pfam14539, DUF4442, Domain of unknown function (DUF4442)	NA|245aa|down_5|NZ_CP018627.1_10174887_10175622_-	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083	NA|420aa|down_6|NZ_CP018627.1_10175677_10176937_-	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters	NA|410aa|down_7|NZ_CP018627.1_10176954_10178184_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|196aa|down_8|NZ_CP018627.1_10178207_10178795_-	pfam16157, DUF4865, Domain of unknown function (DUF4865)	NA|98aa|down_9|NZ_CP018627.1_10179046_10179340_+	COG3462, COG3462, Predicted membrane protein [Function unknown]
GCF_002021875.1_ASM202187v1	NZ_CP018627	Streptomyces hygroscopicus strain XM201 chromosome, complete genome	23	11947252-11947340	23	CRISPRCasFinder	no		WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	Orphan	CTTCCTGCCCCGCGAGCGGAGTTCGGCG	28	0	0	NA	NA	NA	1	1	Orphan	WYL,csa3,DEDDh,cas4,cas3,DinG,Cas14u_CAS-V,casR	NA|65aa|up_1|NZ_CP018627.1_11945130_11945325_-,NA|74aa|up_0|NZ_CP018627.1_11946390_11946612_+,NA|250aa|down_1|NZ_CP018627.1_11950223_11950973_-,NA|196aa|down_3|NZ_CP018627.1_11951525_11952113_+,NA|79aa|down_7|NZ_CP018627.1_11958220_11958457_-,NA|203aa|down_8|NZ_CP018627.1_11958543_11959152_+	NA|67aa|up_9|NZ_CP018627.1_11933838_11934039_-	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain	NA|260aa|up_8|NZ_CP018627.1_11936576_11937356_+	COG3947, COG3947, Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]	NA|126aa|up_7|NZ_CP018627.1_11937585_11937963_-	pfam12680, SnoaL_2, SnoaL-like domain	NA|268aa|up_6|NZ_CP018627.1_11938018_11938822_-	pfam07920, DUF1684, Protein of unknown function (DUF1684)	NA|298aa|up_5|NZ_CP018627.1_11938994_11939888_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|205aa|up_4|NZ_CP018627.1_11940015_11940630_-	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|349aa|up_3|NZ_CP018627.1_11940680_11941727_+	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]	NA|237aa|up_2|NZ_CP018627.1_11944071_11944782_-	smart00706, TECPR, Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins	NA|65aa|up_1|NZ_CP018627.1_11945130_11945325_-	NA	NA|74aa|up_0|NZ_CP018627.1_11946390_11946612_+	NA	NA|523aa|down_0|NZ_CP018627.1_11948643_11950212_-	PRK14995, PRK14995, SmvA family efflux MFS transporter	NA|250aa|down_1|NZ_CP018627.1_11950223_11950973_-	NA	NA|99aa|down_2|NZ_CP018627.1_11950978_11951275_+	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain	NA|196aa|down_3|NZ_CP018627.1_11951525_11952113_+	NA	NA|236aa|down_4|NZ_CP018627.1_11953106_11953814_-	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain	NA|265aa|down_5|NZ_CP018627.1_11955564_11956359_-	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR	NA|532aa|down_6|NZ_CP018627.1_11956543_11958139_-	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|79aa|down_7|NZ_CP018627.1_11958220_11958457_-	NA	NA|203aa|down_8|NZ_CP018627.1_11958543_11959152_+	NA	NA|178aa|down_9|NZ_CP018627.1_11959894_11960428_+	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme
