assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	1	331845-332643	1	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGNGCCGCCGGNN	18	0	0	NA	NA	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP022014.1_331360_331543_-,NA	NA|398aa|up_9|NZ_CP022014.1_321538_322732_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP022014.1_322767_324450_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP022014.1_324466_326662_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP022014.1_326775_327909_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP022014.1_327905_328526_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP022014.1_328622_329204_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP022014.1_329133_329859_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP022014.1_329948_330869_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP022014.1_330908_331337_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP022014.1_331360_331543_-	NA	NA|900aa|down_0|NZ_CP022014.1_334708_337408_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP022014.1_337698_339309_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP022014.1_339332_340241_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP022014.1_340464_342360_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP022014.1_342356_343973_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP022014.1_343969_347962_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP022014.1_347958_348267_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP022014.1_348269_349811_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP022014.1_349859_350153_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP022014.1_350182_350473_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	2	364798-365496	1	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	365086-365127|365161-365193	NZ_CP022014.1_373102-373143|NZ_CP022014.1_371917-371949	NA	10	10	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP022014.1_361810_362113_+,NA|161aa|down_1|NZ_CP022014.1_374891_375374_-,NA|410aa|down_5|NZ_CP022014.1_377490_378720_+	NA|262aa|up_9|NZ_CP022014.1_356505_357291_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP022014.1_357279_358083_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP022014.1_358092_359490_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP022014.1_359668_361444_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP022014.1_361586_361814_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP022014.1_361810_362113_+	NA	NA|74aa|up_3|NZ_CP022014.1_362160_362382_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP022014.1_362378_362804_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP022014.1_362939_363572_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP022014.1_363568_364477_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP022014.1_374232_374904_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP022014.1_374891_375374_-	NA	NA|239aa|down_2|NZ_CP022014.1_375431_376148_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP022014.1_376249_376906_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP022014.1_376975_377467_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP022014.1_377490_378720_+	NA	NA|621aa|down_6|NZ_CP022014.1_378874_380737_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP022014.1_380808_381195_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP022014.1_381197_381860_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP022014.1_381920_382805_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	3	690285-690361	2	CRISPRCasFinder	no	c2c9_V-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|136aa|up_9|NZ_CP022014.1_676180_676588_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP022014.1_676647_677334_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP022014.1_677487_680121_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP022014.1_680143_682531_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP022014.1_682668_683391_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP022014.1_683387_684185_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP022014.1_684186_685074_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP022014.1_685079_686294_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NZ_CP022014.1_686290_687322_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NZ_CP022014.1_687318_688764_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP022014.1_691496_693047_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP022014.1_693098_693491_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP022014.1_693487_693745_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP022014.1_693927_695163_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP022014.1_695413_695827_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP022014.1_695823_696060_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP022014.1_696163_696670_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP022014.1_696783_697254_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP022014.1_697297_698059_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP022014.1_698115_698427_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	4	924282-925229	2	CRT	no	csa3	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	925065-925100|925065-925100|925065-925100	NZ_CP022014.1_673387-673352|NZ_CP022014.1_1211647-1211682|NZ_CP022014.1_2416279-2416244	NA	19	19	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP022014.1_929239_929791_-,NA|81aa|down_8|NZ_CP022014.1_935254_935497_+	NA|685aa|up_9|NZ_CP022014.1_911921_913976_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|389aa|up_8|NZ_CP022014.1_914141_915308_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP022014.1_915395_916412_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP022014.1_916573_917215_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP022014.1_917295_918351_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP022014.1_918402_918795_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP022014.1_918852_919275_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP022014.1_919236_919527_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP022014.1_919631_920537_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP022014.1_920555_921371_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP022014.1_925498_928147_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP022014.1_928614_929259_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP022014.1_929239_929791_-	NA	NA|241aa|down_3|NZ_CP022014.1_929871_930594_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP022014.1_930664_931693_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP022014.1_932381_933152_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP022014.1_933238_934051_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP022014.1_934118_934979_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP022014.1_935254_935497_+	NA	NA|431aa|down_9|NZ_CP022014.1_935773_937066_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	5	1189025-1189133	3	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP022014.1_1178374_1180006_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP022014.1_1180081_1181146_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP022014.1_1181198_1181672_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP022014.1_1181705_1182569_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP022014.1_1182573_1183431_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP022014.1_1183431_1184514_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP022014.1_1184594_1185014_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP022014.1_1185125_1185692_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP022014.1_1185688_1186084_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|674aa|up_0|NZ_CP022014.1_1186111_1188133_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP022014.1_1190410_1192174_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP022014.1_1192170_1192944_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP022014.1_1192955_1193993_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP022014.1_1194179_1195016_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP022014.1_1195131_1195983_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP022014.1_1196056_1197274_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP022014.1_1197326_1198271_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP022014.1_1198493_1199561_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP022014.1_1199617_1201012_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP022014.1_1201213_1201936_+	pfam06271, RDD, RDD family
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	6	1570199-1571271	4	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	1570399-1570420	NZ_CP022014.1_1209964-1209943	NA	15	15	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP022014.1_1561962_1562280_+,NA	NA|103aa|up_9|NZ_CP022014.1_1559477_1559786_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP022014.1_1559782_1561402_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP022014.1_1561962_1562280_+	NA	NA|209aa|up_6|NZ_CP022014.1_1562414_1563041_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP022014.1_1563106_1563439_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP022014.1_1563454_1564711_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP022014.1_1564838_1566050_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP022014.1_1566122_1567601_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP022014.1_1567597_1568983_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP022014.1_1569060_1570095_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP022014.1_1572125_1572527_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP022014.1_1572523_1572781_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP022014.1_1572863_1573823_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP022014.1_1573847_1574810_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP022014.1_1574943_1575546_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP022014.1_1575626_1577594_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP022014.1_1577611_1578436_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP022014.1_1578604_1579087_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP022014.1_1579158_1579983_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP022014.1_1580179_1581118_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	7	1635052-1635278	1	PILER-CR	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP022014.1_1621140_1621254_-,NA|137aa|up_7|NZ_CP022014.1_1621303_1621714_-,NA|288aa|down_2|NZ_CP022014.1_1639104_1639968_+	NA|162aa|up_9|NZ_CP022014.1_1620223_1620709_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP022014.1_1621140_1621254_-	NA	NA|137aa|up_7|NZ_CP022014.1_1621303_1621714_-	NA	NA|248aa|up_6|NZ_CP022014.1_1621730_1622474_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|305aa|up_5|NZ_CP022014.1_1622470_1623385_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP022014.1_1623437_1624982_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP022014.1_1624978_1626100_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP022014.1_1626116_1628219_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1405aa|up_1|NZ_CP022014.1_1628657_1632872_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP022014.1_1633273_1634200_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP022014.1_1636805_1638071_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP022014.1_1638098_1639085_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP022014.1_1639104_1639968_+	NA	NA|311aa|down_3|NZ_CP022014.1_1639917_1640850_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP022014.1_1640961_1641747_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP022014.1_1641743_1642685_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP022014.1_1642840_1644616_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP022014.1_1644663_1645470_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP022014.1_1645466_1648007_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP022014.1_1648003_1649197_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	8	2067316-2067570	3	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2067397-2067414|2067397-2067414|2067487-2067504	NZ_CP022014.1_399398-399381|NZ_CP022014.1_605613-605596|NZ_CP022014.1_3451066-3451049	NA	5	5	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP022014.1_2066675_2066939_-,NA	NA|165aa|up_9|NZ_CP022014.1_2053025_2053520_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP022014.1_2053867_2054545_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP022014.1_2054903_2057729_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP022014.1_2057955_2058816_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP022014.1_2058856_2059723_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP022014.1_2059727_2061614_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP022014.1_2061629_2063663_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP022014.1_2063782_2066008_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP022014.1_2066283_2066679_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP022014.1_2066675_2066939_-	NA	NA|346aa|down_0|NZ_CP022014.1_2068707_2069745_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP022014.1_2069744_2071112_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP022014.1_2071285_2072722_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP022014.1_2072757_2074209_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP022014.1_2074238_2075189_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP022014.1_2075203_2075620_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP022014.1_2075897_2076320_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|101aa|down_7|NZ_CP022014.1_2076368_2076671_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP022014.1_2076667_2076982_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP022014.1_2076981_2078715_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	9	2149184-2149403	5	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP022014.1_2137794_2138202_-,NA|127aa|down_5|NZ_CP022014.1_2156919_2157300_-	NA|155aa|up_9|NZ_CP022014.1_2131122_2131587_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP022014.1_2131762_2133985_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP022014.1_2134022_2134466_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP022014.1_2134579_2135173_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP022014.1_2135255_2135861_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP022014.1_2135960_2136965_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP022014.1_2137064_2137817_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP022014.1_2137794_2138202_-	NA	NA|767aa|up_1|NZ_CP022014.1_2138336_2140637_+	PLN02892, PLN02892, isocitrate lyase	NA|421aa|up_0|NZ_CP022014.1_2144760_2146022_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|155aa|down_0|NZ_CP022014.1_2151430_2151895_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP022014.1_2151992_2152856_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP022014.1_2152893_2154165_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP022014.1_2154436_2155552_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP022014.1_2155542_2156883_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP022014.1_2156919_2157300_-	NA	NA|621aa|down_6|NZ_CP022014.1_2157456_2159319_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP022014.1_2159326_2159806_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP022014.1_2160042_2160816_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP022014.1_2160819_2161587_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	10	3122712-3123859	2,6,4	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-C,Type III-A,Type III-D	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	13,14,15	15	TypeIII-B,TypeIII-C,TypeIII-A,TypeIII-D	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP022014.1_3115991_3116246_-,NA|135aa|up_7|NZ_CP022014.1_3116393_3116798_+,NA|64aa|up_6|NZ_CP022014.1_3116794_3116986_+,NA|86aa|up_4|NZ_CP022014.1_3118572_3118830_+,NA|104aa|up_3|NZ_CP022014.1_3118934_3119246_+,NA|203aa|up_2|NZ_CP022014.1_3119665_3120274_+,NA	NA|92aa|up_9|NZ_CP022014.1_3115540_3115816_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP022014.1_3115991_3116246_-	NA	NA|135aa|up_7|NZ_CP022014.1_3116393_3116798_+	NA	NA|64aa|up_6|NZ_CP022014.1_3116794_3116986_+	NA	NA|385aa|up_5|NZ_CP022014.1_3117184_3118339_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP022014.1_3118572_3118830_+	NA	NA|104aa|up_3|NZ_CP022014.1_3118934_3119246_+	NA	NA|203aa|up_2|NZ_CP022014.1_3119665_3120274_+	NA	NA|470aa|up_1|NZ_CP022014.1_3120344_3121754_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP022014.1_3121750_3122563_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP022014.1_3123890_3125152_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	csm3gr7|237aa|down_1|NZ_CP022014.1_3125515_3126226_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_2|NZ_CP022014.1_3126235_3126610_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_3|NZ_CP022014.1_3126606_3129045_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_4|NZ_CP022014.1_3129041_3129764_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_5|NZ_CP022014.1_3130163_3130709_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|295aa|down_6|NZ_CP022014.1_3130980_3131865_-	COG2253, COG2253, Uncharacterized conserved protein [Function unknown]	NA|296aa|down_7|NZ_CP022014.1_3131867_3132755_-	pfam09407, AbiEi_1, AbiEi antitoxin C-terminal domain	NA|182aa|down_8|NZ_CP022014.1_3133059_3133605_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|90aa|down_9|NZ_CP022014.1_3133601_3133871_-	COG5552, COG5552, Uncharacterized conserved protein [Function unknown]
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	11	3666678-3666796	7	CRISPRCasFinder	no	cas3	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Unclear	GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	30	1	1	3666708-3666766	NZ_CP022014.1_3666771-3666829	NA	1	1	Unclear	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|138aa|down_6|NZ_CP022014.1_3672429_3672843_-,NA|126aa|down_7|NZ_CP022014.1_3672877_3673255_-	NA|719aa|up_9|NZ_CP022014.1_3653504_3655661_+	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism]	NA|223aa|up_8|NZ_CP022014.1_3655657_3656326_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|395aa|up_7|NZ_CP022014.1_3656426_3657611_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|765aa|up_6|NZ_CP022014.1_3657615_3659910_+	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]	NA|390aa|up_5|NZ_CP022014.1_3659898_3661068_-	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|175aa|up_4|NZ_CP022014.1_3661092_3661617_-	PLN02948, PLN02948, phosphoribosylaminoimidazole carboxylase	NA|430aa|up_3|NZ_CP022014.1_3661613_3662903_-	TIGR01161, N5-carboxyaminoimidazole_ribonucleotide_synthase, phosphoribosylaminoimidazole carboxylase, PurK protein	NA|273aa|up_2|NZ_CP022014.1_3662856_3663675_+	COG2246, COG2246, Predicted membrane protein [Function unknown]	NA|173aa|up_1|NZ_CP022014.1_3663629_3664148_-	pfam03703, bPH_2, Bacterial PH domain	NA|267aa|up_0|NZ_CP022014.1_3664190_3664991_-	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|223aa|down_0|NZ_CP022014.1_3667062_3667731_+	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|298aa|down_1|NZ_CP022014.1_3667771_3668665_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|144aa|down_2|NZ_CP022014.1_3668661_3669093_+	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]	NA|601aa|down_3|NZ_CP022014.1_3669200_3671003_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|262aa|down_4|NZ_CP022014.1_3671012_3671798_-	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|146aa|down_5|NZ_CP022014.1_3671794_3672232_-	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]	NA|138aa|down_6|NZ_CP022014.1_3672429_3672843_-	NA	NA|126aa|down_7|NZ_CP022014.1_3672877_3673255_-	NA	NA|450aa|down_8|NZ_CP022014.1_3673288_3674638_-	PRK08297, PRK08297, L-lysine aminotransferase; Provisional	NA|151aa|down_9|NZ_CP022014.1_3674688_3675141_-	smart00344, HTH_ASNC, helix_turn_helix ASNC type
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	12	3744891-3745467	5	CRT	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGTTGCCNCCGNNGCCGCCG	25	0	0	NA	NA	NA	7	7	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP022014.1_3759699_3759987_-,NA|87aa|down_8|NZ_CP022014.1_3773106_3773367_-	NA|282aa|up_9|NZ_CP022014.1_3724240_3725086_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP022014.1_3725560_3726001_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP022014.1_3726034_3726904_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP022014.1_3726924_3727935_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP022014.1_3728219_3728852_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP022014.1_3728918_3730148_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP022014.1_3730430_3731780_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP022014.1_3731791_3732931_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP022014.1_3732927_3733659_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2538aa|up_0|NZ_CP022014.1_3733667_3741281_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP022014.1_3747569_3747827_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP022014.1_3748082_3757556_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP022014.1_3758181_3758628_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP022014.1_3758664_3759405_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP022014.1_3759699_3759987_-	NA	NA|265aa|down_5|NZ_CP022014.1_3771716_3772511_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_CP022014.1_3772592_3772964_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_7|NZ_CP022014.1_3772861_3773080_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_CP022014.1_3773106_3773367_-	NA	NA|130aa|down_9|NZ_CP022014.1_3773481_3773871_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	13	3852753-3852842	8	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|77aa|up_6|NZ_CP022014.1_3846148_3846379_+,NA|121aa|up_5|NZ_CP022014.1_3846482_3846845_-,NA|73aa|up_2|NZ_CP022014.1_3850818_3851037_-,NA|121aa|down_0|NZ_CP022014.1_3853827_3854190_-,NA|52aa|down_2|NZ_CP022014.1_3856031_3856187_-,NA|52aa|down_3|NZ_CP022014.1_3856211_3856367_-,NA|238aa|down_6|NZ_CP022014.1_3860402_3861116_-	NA|212aa|up_9|NZ_CP022014.1_3843827_3844463_-	COG1214, COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|169aa|up_8|NZ_CP022014.1_3844459_3844966_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_7|NZ_CP022014.1_3844962_3846189_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_6|NZ_CP022014.1_3846148_3846379_+	NA	NA|121aa|up_5|NZ_CP022014.1_3846482_3846845_-	NA	NA|177aa|up_4|NZ_CP022014.1_3847803_3848334_+	pfam00823, PPE, PPE family	NA|725aa|up_3|NZ_CP022014.1_3848651_3850826_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|73aa|up_2|NZ_CP022014.1_3850818_3851037_-	NA	NA|100aa|up_1|NZ_CP022014.1_3851531_3851831_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_CP022014.1_3851916_3852459_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP022014.1_3853827_3854190_-	NA	NA|179aa|down_1|NZ_CP022014.1_3854352_3854889_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP022014.1_3856031_3856187_-	NA	NA|52aa|down_3|NZ_CP022014.1_3856211_3856367_-	NA	NA|461aa|down_4|NZ_CP022014.1_3857559_3858942_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_CP022014.1_3858979_3860401_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_CP022014.1_3860402_3861116_-	NA	NA|285aa|down_7|NZ_CP022014.1_3861126_3861981_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_CP022014.1_3862202_3864077_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_CP022014.1_3864098_3864575_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_002208235.1_ASM220823v1	NZ_CP022014	Mycobacterium tuberculosis strain MTB2 chromosome, complete genome	14	4117170-4117258	9	CRISPRCasFinder	no		csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP022014.1_4107756_4108527_-,NA|119aa|up_3|NZ_CP022014.1_4113661_4114018_+,NA|52aa|up_2|NZ_CP022014.1_4114117_4114273_+,NA|233aa|up_0|NZ_CP022014.1_4116274_4116973_-,NA|126aa|down_6|NZ_CP022014.1_4122493_4122871_+	NA|288aa|up_9|NZ_CP022014.1_4106138_4107002_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP022014.1_4107756_4108527_-	NA	NA|549aa|up_7|NZ_CP022014.1_4108523_4110170_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP022014.1_4110166_4111030_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP022014.1_4111022_4111949_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP022014.1_4111950_4113576_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP022014.1_4113661_4114018_+	NA	NA|52aa|up_2|NZ_CP022014.1_4114117_4114273_+	NA	NA|652aa|up_1|NZ_CP022014.1_4114283_4116239_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP022014.1_4116274_4116973_-	NA	NA|173aa|down_0|NZ_CP022014.1_4117318_4117837_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP022014.1_4117837_4118821_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP022014.1_4118813_4120007_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP022014.1_4120012_4120834_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP022014.1_4120965_4121649_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP022014.1_4121648_4122386_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP022014.1_4122493_4122871_+	NA	NA|225aa|down_7|NZ_CP022014.1_4122969_4123644_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP022014.1_4123749_4124544_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP022014.1_4124550_4125006_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
