assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	1	366421-367119	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366709-366750|366784-366816	NZ_CP023589.1_374740-374781|NZ_CP023589.1_373555-373587	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023589.1_363433_363736_+,NA|161aa|down_1|NZ_CP023589.1_376529_377012_-,NA|410aa|down_5|NZ_CP023589.1_379128_380358_+	NA|262aa|up_9|NZ_CP023589.1_358128_358914_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023589.1_358902_359706_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023589.1_359715_361113_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023589.1_361291_363067_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023589.1_363209_363437_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023589.1_363433_363736_+	NA	NA|74aa|up_3|NZ_CP023589.1_363783_364005_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023589.1_364001_364427_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023589.1_364562_365195_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023589.1_365191_366100_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023589.1_375870_376542_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023589.1_376529_377012_-	NA	NA|239aa|down_2|NZ_CP023589.1_377069_377786_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023589.1_377887_378544_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023589.1_378613_379105_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023589.1_379128_380358_+	NA	NA|621aa|down_6|NZ_CP023589.1_380512_382375_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023589.1_382446_382833_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023589.1_382835_383498_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023589.1_383558_384443_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	2	691877-691953	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023589.1_677561_677777_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023589.1_677773_678181_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023589.1_678240_678927_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023589.1_679080_681714_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023589.1_681736_684124_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023589.1_684261_684984_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023589.1_684980_685778_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023589.1_685779_686667_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023589.1_686672_687887_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023589.1_688910_690356_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023589.1_693088_694639_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023589.1_694690_695083_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023589.1_695079_695337_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023589.1_695519_696755_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023589.1_697005_697419_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023589.1_697415_697652_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023589.1_697755_698262_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023589.1_698375_698846_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023589.1_698889_699651_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023589.1_699707_700019_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	3	926473-927420	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927256-927291|927256-927291|927256-927291	NZ_CP023589.1_674980-674945|NZ_CP023589.1_1213602-1213637|NZ_CP023589.1_2423583-2423548	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023589.1_931430_931982_-,NA|81aa|down_8|NZ_CP023589.1_937445_937688_+	NA|685aa|up_9|NZ_CP023589.1_914109_916164_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023589.1_916329_917499_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023589.1_917586_918603_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023589.1_918764_919406_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023589.1_919486_920542_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023589.1_920593_920986_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023589.1_921043_921466_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023589.1_921427_921718_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023589.1_921822_922728_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023589.1_922746_923562_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023589.1_927689_930338_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023589.1_930805_931450_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023589.1_931430_931982_-	NA	NA|218aa|down_3|NZ_CP023589.1_932131_932785_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023589.1_932855_933884_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023589.1_934572_935343_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023589.1_935429_936242_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023589.1_936309_937170_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023589.1_937445_937688_+	NA	NA|431aa|down_9|NZ_CP023589.1_937964_939257_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	4	1191178-1191286	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023589.1_1180545_1182177_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023589.1_1182252_1183317_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023589.1_1183369_1183843_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023589.1_1183876_1184740_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023589.1_1184744_1185602_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023589.1_1185602_1186685_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023589.1_1186765_1187185_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023589.1_1187296_1187863_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023589.1_1187859_1188255_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023589.1_1188282_1190286_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023589.1_1192371_1194135_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023589.1_1194131_1194905_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023589.1_1194916_1195954_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023589.1_1196140_1196977_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023589.1_1197092_1197944_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023589.1_1198017_1199235_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023589.1_1199287_1200232_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023589.1_1200454_1201522_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023589.1_1201578_1202973_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023589.1_1203174_1203897_+	pfam06271, RDD, RDD family
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	5	1211812-1212659	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	2	71	1212369-1212390|1212369-1212390|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504|1212486-1212504	NZ_CP023589.1_837285-837306|NZ_CP023589.1_1217497-1217518|NZ_CP023589.1_1572681-1572663|NZ_CP023589.1_674644-674626|NZ_CP023589.1_1213329-1213347|NZ_CP023589.1_1217470-1217488|NZ_CP023589.1_1217542-1217560|NZ_CP023589.1_1630553-1630535|NZ_CP023589.1_1633379-1633361|NZ_CP023589.1_1990666-1990648|NZ_CP023589.1_2061391-2061373|NZ_CP023589.1_2061838-2061820|NZ_CP023589.1_2061937-2061919|NZ_CP023589.1_2801899-2801881|NZ_CP023589.1_2805427-2805409|NZ_CP023589.1_150187-150205|NZ_CP023589.1_333754-333736|NZ_CP023589.1_335173-335155|NZ_CP023589.1_335626-335608|NZ_CP023589.1_335677-335659|NZ_CP023589.1_335686-335668|NZ_CP023589.1_337961-337943|NZ_CP023589.1_338090-338072|NZ_CP023589.1_338357-338339|NZ_CP023589.1_338386-338404|NZ_CP023589.1_338480-338462|NZ_CP023589.1_363011-362993|NZ_CP023589.1_443310-443292|NZ_CP023589.1_546654-546636|NZ_CP023589.1_623844-623862|NZ_CP023589.1_624066-624084|NZ_CP023589.1_673810-673792|NZ_CP023589.1_840068-840086|NZ_CP023589.1_1090841-1090859|NZ_CP023589.1_1091489-1091507|NZ_CP023589.1_1095547-1095529|NZ_CP023589.1_1212858-1212876|NZ_CP023589.1_1213248-1213266|NZ_CP023589.1_1217890-1217908|NZ_CP023589.1_1618517-1618499|NZ_CP023589.1_1618970-1618952|NZ_CP023589.1_1635892-1635874|NZ_CP023589.1_1635901-1635883|NZ_CP023589.1_1864180-1864162|NZ_CP023589.1_1864708-1864690|NZ_CP023589.1_1989940-1989922|NZ_CP023589.1_2001303-2001321|NZ_CP023589.1_2088661-2088643|NZ_CP023589.1_2303361-2303343|NZ_CP023589.1_2356812-2356794|NZ_CP023589.1_2419409-2419427|NZ_CP023589.1_2423496-2423478|NZ_CP023589.1_2568989-2568971|NZ_CP023589.1_2693287-2693305|NZ_CP023589.1_2795214-2795196|NZ_CP023589.1_2795796-2795778|NZ_CP023589.1_3054386-3054404|NZ_CP023589.1_3054485-3054503|NZ_CP023589.1_3705299-3705317|NZ_CP023589.1_3737276-3737258|NZ_CP023589.1_3737900-3737882|NZ_CP023589.1_3738143-3738125|NZ_CP023589.1_3738276-3738258|NZ_CP023589.1_3802121-3802139|NZ_CP023589.1_3802304-3802322|NZ_CP023589.1_3802472-3802490|NZ_CP023589.1_3930297-3930315|NZ_CP023589.1_3932027-3932045|NZ_CP023589.1_3940536-3940554|NZ_CP023589.1_4031511-4031493|NZ_CP023589.1_4094042-4094060	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023589.1_1207244_1207511_+,NA|61aa|down_3|NZ_CP023589.1_1215077_1215260_+,NA|35aa|down_4|NZ_CP023589.1_1215369_1215474_+	NA|465aa|up_9|NZ_CP023589.1_1201578_1202973_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023589.1_1203174_1203897_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023589.1_1203928_1205095_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023589.1_1205165_1205660_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023589.1_1205845_1206280_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023589.1_1206381_1207248_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023589.1_1207244_1207511_+	NA	NA|674aa|up_2|NZ_CP023589.1_1207497_1209519_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023589.1_1209617_1210346_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023589.1_1210456_1211245_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023589.1_1213892_1214213_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023589.1_1214365_1214800_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP023589.1_1214898_1215066_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023589.1_1215077_1215260_+	NA	NA|35aa|down_4|NZ_CP023589.1_1215369_1215474_+	NA	NA|152aa|down_5|NZ_CP023589.1_1215451_1215907_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023589.1_1216321_1218883_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023589.1_1219100_1220039_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023589.1_1220426_1221707_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023589.1_1221811_1222639_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	6	1488946-1489065	1	PILER-CR	no	DinG	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type IV-A	AACCCGCCGGTGCCGCCGGCACCGCCGGCG	30	1	1	1488976-1488994	NZ_CP023589.1_399557-399575	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|99aa|up_3|NZ_CP023589.1_1484836_1485133_+,NA	NA|166aa|up_9|NZ_CP023589.1_1476988_1477486_-	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional	NA|497aa|up_8|NZ_CP023589.1_1477482_1478973_-	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]	NA|542aa|up_7|NZ_CP023589.1_1479053_1480679_-	cd07302, CHD, cyclase homology domain	NA|536aa|up_6|NZ_CP023589.1_1480748_1482356_-	cd07302, CHD, cyclase homology domain	NA|568aa|up_5|NZ_CP023589.1_1482368_1484072_-	COG2114, CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]	NA|224aa|up_4|NZ_CP023589.1_1484142_1484814_+	PRK03298, PRK03298, endonuclease NucS	NA|99aa|up_3|NZ_CP023589.1_1484836_1485133_+	NA	NA|153aa|up_2|NZ_CP023589.1_1485167_1485626_-	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE)	NA|394aa|up_1|NZ_CP023589.1_1485704_1486886_+	PRK05790, PRK05790, putative acyltransferase; Provisional	NA|305aa|up_0|NZ_CP023589.1_1487015_1487930_+	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]	NA|732aa|down_0|NZ_CP023589.1_1489971_1492167_-	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB	NA|702aa|down_1|NZ_CP023589.1_1492174_1494280_-	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins	NA|864aa|down_2|NZ_CP023589.1_1494418_1497010_+	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase	DinG|665aa|down_3|NZ_CP023589.1_1497049_1499044_-	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]	NA|449aa|down_4|NZ_CP023589.1_1499067_1500414_-	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated	NA|102aa|down_5|NZ_CP023589.1_1500515_1500821_+	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed	NA|219aa|down_6|NZ_CP023589.1_1500780_1501437_+	pfam09438, DUF2017, Domain of unknown function (DUF2017)	NA|345aa|down_7|NZ_CP023589.1_1501453_1502488_+	COG3191, DmpA, L-aminopeptidase/D-esterase [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|147aa|down_8|NZ_CP023589.1_1502495_1502936_+	cd08070, MPN_like, Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding)	NA|94aa|down_9|NZ_CP023589.1_1502957_1503239_+	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	7	1636470-1636696	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP023589.1_1622978_1623092_-,NA|137aa|up_7|NZ_CP023589.1_1623141_1623552_-,NA|288aa|down_2|NZ_CP023589.1_1640534_1641398_+	NA|162aa|up_9|NZ_CP023589.1_1622061_1622547_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP023589.1_1622978_1623092_-	NA	NA|137aa|up_7|NZ_CP023589.1_1623141_1623552_-	NA	NA|248aa|up_6|NZ_CP023589.1_1623568_1624312_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP023589.1_1624308_1625220_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP023589.1_1625272_1626817_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP023589.1_1626813_1627935_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP023589.1_1627951_1630054_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP023589.1_1630492_1634482_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP023589.1_1634883_1635810_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP023589.1_1638235_1639501_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP023589.1_1639528_1640515_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP023589.1_1640534_1641398_+	NA	NA|311aa|down_3|NZ_CP023589.1_1641347_1642280_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP023589.1_1642391_1643177_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP023589.1_1643173_1644115_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP023589.1_1644217_1645993_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP023589.1_1646040_1646847_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP023589.1_1646843_1649384_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP023589.1_1649380_1650574_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	8	2088133-2088387	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088214-2088231|2088214-2088231|2088304-2088321	NZ_CP023589.1_401036-401019|NZ_CP023589.1_607299-607282|NZ_CP023589.1_3449999-3449982	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023589.1_2087492_2087756_-,NA	NA|165aa|up_9|NZ_CP023589.1_2073786_2074281_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023589.1_2074684_2075362_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023589.1_2075720_2078546_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023589.1_2078772_2079633_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023589.1_2079673_2080540_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023589.1_2080544_2082431_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023589.1_2082446_2084480_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023589.1_2084599_2086825_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023589.1_2087100_2087496_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023589.1_2087492_2087756_-	NA	NA|346aa|down_0|NZ_CP023589.1_2089524_2090562_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023589.1_2090561_2091929_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023589.1_2092102_2093539_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023589.1_2093574_2095026_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023589.1_2095055_2096006_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023589.1_2096020_2096437_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023589.1_2096714_2097137_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023589.1_2097185_2097488_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023589.1_2097484_2097799_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023589.1_2097798_2099532_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	9	2163225-2163329	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023589.1_2159769_2160177_-,NA|127aa|down_6|NZ_CP023589.1_2176398_2176779_-	NA|216aa|up_9|NZ_CP023589.1_2153083_2153731_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023589.1_2153737_2155960_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023589.1_2155997_2156441_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023589.1_2156554_2157148_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023589.1_2157230_2157836_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023589.1_2157935_2158940_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023589.1_2159039_2159792_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023589.1_2159769_2160177_-	NA	NA|368aa|up_1|NZ_CP023589.1_2160311_2161415_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023589.1_2161414_2162611_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023589.1_2167497_2170461_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023589.1_2170909_2171374_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023589.1_2171471_2172335_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023589.1_2172372_2173644_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023589.1_2173915_2175031_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023589.1_2175021_2176362_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023589.1_2176398_2176779_-	NA	NA|621aa|down_7|NZ_CP023589.1_2176935_2178798_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023589.1_2178805_2179285_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023589.1_2179521_2180295_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	10	2168663-2168882	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP023589.1_2159769_2160177_-,NA|127aa|down_5|NZ_CP023589.1_2176398_2176779_-	NA|741aa|up_9|NZ_CP023589.1_2153737_2155960_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP023589.1_2155997_2156441_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP023589.1_2156554_2157148_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP023589.1_2157230_2157836_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP023589.1_2157935_2158940_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP023589.1_2159039_2159792_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP023589.1_2159769_2160177_-	NA	NA|368aa|up_2|NZ_CP023589.1_2160311_2161415_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP023589.1_2161414_2162611_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP023589.1_2162780_2167160_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP023589.1_2170909_2171374_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023589.1_2171471_2172335_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023589.1_2172372_2173644_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023589.1_2173915_2175031_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023589.1_2175021_2176362_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023589.1_2176398_2176779_-	NA	NA|621aa|down_6|NZ_CP023589.1_2176935_2178798_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023589.1_2178805_2179285_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023589.1_2179521_2180295_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023589.1_2180298_2181066_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	11	3118977-3120331	3,7,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-B,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	16,17,18	18	TypeIII-C,TypeIII-B,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023589.1_3112256_3112511_-,NA|135aa|up_7|NZ_CP023589.1_3112658_3113063_+,NA|64aa|up_6|NZ_CP023589.1_3113059_3113251_+,NA|86aa|up_4|NZ_CP023589.1_3114837_3115095_+,NA|104aa|up_3|NZ_CP023589.1_3115199_3115511_+,NA|203aa|up_2|NZ_CP023589.1_3115930_3116539_+,NA	NA|92aa|up_9|NZ_CP023589.1_3111805_3112081_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023589.1_3112256_3112511_-	NA	NA|135aa|up_7|NZ_CP023589.1_3112658_3113063_+	NA	NA|64aa|up_6|NZ_CP023589.1_3113059_3113251_+	NA	NA|385aa|up_5|NZ_CP023589.1_3113449_3114604_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023589.1_3114837_3115095_+	NA	NA|104aa|up_3|NZ_CP023589.1_3115199_3115511_+	NA	NA|203aa|up_2|NZ_CP023589.1_3115930_3116539_+	NA	NA|470aa|up_1|NZ_CP023589.1_3116609_3118019_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023589.1_3118015_3118828_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023589.1_3120357_3121619_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023589.1_3123416_3123758_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023589.1_3123758_3124775_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023589.1_3124787_3125936_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023589.1_3126031_3127159_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023589.1_3127155_3128064_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023589.1_3128044_3128755_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023589.1_3128764_3129139_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023589.1_3129135_3131574_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023589.1_3131570_3132293_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	12	3121654-3123368	8,4,4,5	CRISPRCasFinder,CRT,PILER-CR,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-B,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A:II-B,III-A	23,23,20,20	23	TypeIII-C,TypeIII-B,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023589.1_3112256_3112511_-,NA|135aa|up_8|NZ_CP023589.1_3112658_3113063_+,NA|64aa|up_7|NZ_CP023589.1_3113059_3113251_+,NA|86aa|up_5|NZ_CP023589.1_3114837_3115095_+,NA|104aa|up_4|NZ_CP023589.1_3115199_3115511_+,NA|203aa|up_3|NZ_CP023589.1_3115930_3116539_+,NA	NA|85aa|up_9|NZ_CP023589.1_3112256_3112511_-	NA	NA|135aa|up_8|NZ_CP023589.1_3112658_3113063_+	NA	NA|64aa|up_7|NZ_CP023589.1_3113059_3113251_+	NA	NA|385aa|up_6|NZ_CP023589.1_3113449_3114604_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023589.1_3114837_3115095_+	NA	NA|104aa|up_4|NZ_CP023589.1_3115199_3115511_+	NA	NA|203aa|up_3|NZ_CP023589.1_3115930_3116539_+	NA	NA|470aa|up_2|NZ_CP023589.1_3116609_3118019_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023589.1_3118015_3118828_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023589.1_3120357_3121619_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023589.1_3123416_3123758_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023589.1_3123758_3124775_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023589.1_3124787_3125936_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023589.1_3126031_3127159_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023589.1_3127155_3128064_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023589.1_3128044_3128755_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023589.1_3128764_3129139_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023589.1_3129135_3131574_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023589.1_3131570_3132293_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023589.1_3132692_3133238_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	13	3740470-3741011	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023589.1_3755094_3755382_-,NA|87aa|down_9|NZ_CP023589.1_3768502_3768763_-	NA|282aa|up_9|NZ_CP023589.1_3719721_3720567_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023589.1_3721041_3721482_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023589.1_3721515_3722385_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023589.1_3722405_3723416_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023589.1_3723700_3724333_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023589.1_3724399_3725629_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023589.1_3725911_3727261_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023589.1_3727272_3728412_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023589.1_3728408_3729140_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023589.1_3729148_3736720_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023589.1_3742964_3743222_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023589.1_3743477_3752951_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023589.1_3753576_3754023_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023589.1_3754059_3754800_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023589.1_3755094_3755382_-	NA	NA|3717aa|down_5|NZ_CP023589.1_3755718_3766869_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023589.1_3767112_3767907_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023589.1_3767988_3768360_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023589.1_3768257_3768476_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023589.1_3768502_3768763_-	NA
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	14	3948144-3949895	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948735-3948770|3948735-3948770|3948735-3948770|3948735-3948770|3948735-3948770|3949626-3949652|3949626-3949652|3949626-3949652|3949626-3949652	NZ_CP023589.1_3946851-3946886|NZ_CP023589.1_3947193-3947228|NZ_CP023589.1_3947784-3947819|NZ_CP023589.1_3948135-3948170|NZ_CP023589.1_3932582-3932617|NZ_CP023589.1_361951-361977|NZ_CP023589.1_3941037-3941063|NZ_CP023589.1_3941373-3941399|NZ_CP023589.1_3941719-3941745	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023589.1_3953210_3954050_+	NA|255aa|up_9|NZ_CP023589.1_3919865_3920630_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_8|NZ_CP023589.1_3920855_3921809_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_7|NZ_CP023589.1_3921833_3922025_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_6|NZ_CP023589.1_3922239_3923442_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_5|NZ_CP023589.1_3923466_3924588_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_4|NZ_CP023589.1_3924658_3926167_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1385aa|up_3|NZ_CP023589.1_3926337_3930492_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023589.1_3936656_3938204_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023589.1_3938200_3939037_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023589.1_3944871_3945528_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023589.1_3950603_3952250_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023589.1_3952323_3953115_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023589.1_3953210_3954050_+	NA	NA|399aa|down_3|NZ_CP023589.1_3954104_3955301_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023589.1_3955329_3956040_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023589.1_3956104_3957148_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023589.1_3957300_3958212_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023589.1_3958227_3959292_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023589.1_3959308_3960493_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023589.1_3960534_3961566_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447195.1_ASM244719v1	NZ_CP023589	Mycobacterium tuberculosis strain TBV5000 chromosome, complete genome	15	4110459-4110547	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023589.1_4101045_4101816_-,NA|119aa|up_3|NZ_CP023589.1_4106950_4107307_+,NA|52aa|up_2|NZ_CP023589.1_4107406_4107562_+,NA|233aa|up_0|NZ_CP023589.1_4109563_4110262_-,NA|126aa|down_6|NZ_CP023589.1_4115782_4116160_+	NA|288aa|up_9|NZ_CP023589.1_4099427_4100291_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023589.1_4101045_4101816_-	NA	NA|549aa|up_7|NZ_CP023589.1_4101812_4103459_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023589.1_4103455_4104319_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023589.1_4104311_4105238_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023589.1_4105239_4106865_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023589.1_4106950_4107307_+	NA	NA|52aa|up_2|NZ_CP023589.1_4107406_4107562_+	NA	NA|652aa|up_1|NZ_CP023589.1_4107572_4109528_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023589.1_4109563_4110262_-	NA	NA|173aa|down_0|NZ_CP023589.1_4110607_4111126_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023589.1_4111126_4112110_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023589.1_4112102_4113296_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023589.1_4113301_4114123_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023589.1_4114254_4114938_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023589.1_4114937_4115675_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023589.1_4115782_4116160_+	NA	NA|225aa|down_7|NZ_CP023589.1_4116258_4116933_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023589.1_4117038_4117833_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023589.1_4117839_4118295_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
