assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	1	335370-335942	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGGCNCCGCCGNNGCCG	21	1	1	335889-335921	NZ_CP023602.1_338643-338675	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP023602.1_333144_333327_-,NA	NA|398aa|up_9|NZ_CP023602.1_323322_324516_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP023602.1_324551_326234_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP023602.1_326250_328446_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP023602.1_328559_329693_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP023602.1_329689_330310_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP023602.1_330406_330988_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP023602.1_330917_331643_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP023602.1_331732_332653_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP023602.1_332692_333121_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP023602.1_333144_333327_-	NA	NA|835aa|down_0|NZ_CP023602.1_336544_339049_-	pfam00934, PE, PE family	NA|537aa|down_1|NZ_CP023602.1_339339_340950_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_2|NZ_CP023602.1_340973_341882_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_3|NZ_CP023602.1_342105_344001_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_4|NZ_CP023602.1_343997_345614_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_5|NZ_CP023602.1_345610_349603_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_6|NZ_CP023602.1_349599_349908_+	pfam00934, PE, PE family	NA|514aa|down_7|NZ_CP023602.1_349910_351452_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_8|NZ_CP023602.1_351500_351794_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_9|NZ_CP023602.1_351823_352114_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	2	337698-338666	2,1	CRT,PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	NNNNNNCCGCCGGCGCCGCCG,ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	21,43	0	0	NA	NA	NA:NA	15,2	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP023602.1_333144_333327_-,NA	NA|561aa|up_9|NZ_CP023602.1_324551_326234_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP023602.1_326250_328446_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP023602.1_328559_329693_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP023602.1_329689_330310_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP023602.1_330406_330988_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP023602.1_330917_331643_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP023602.1_331732_332653_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP023602.1_332692_333121_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP023602.1_333144_333327_-	NA	NA|958aa|up_0|NZ_CP023602.1_333421_336295_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_CP023602.1_339339_340950_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP023602.1_340973_341882_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP023602.1_342105_344001_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP023602.1_343997_345614_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP023602.1_345610_349603_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP023602.1_349599_349908_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP023602.1_349910_351452_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP023602.1_351500_351794_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP023602.1_351823_352114_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP023602.1_352124_353012_+	pfam14011, ESX-1_EspG, EspG family
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	3	631236-631373	3	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	631254-631271|631254-631271|631338-631355	NZ_CP023602.1_22466-22483|NZ_CP023602.1_1412034-1412051|NZ_CP023602.1_973202-973219	NA	3	3	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NZ_CP023602.1_622074_622236_-,NA|478aa|up_0|NZ_CP023602.1_628251_629685_-,NA|450aa|down_2|NZ_CP023602.1_633008_634358_-,NA|93aa|down_5|NZ_CP023602.1_635888_636167_-	NA|325aa|up_9|NZ_CP023602.1_619844_620819_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP023602.1_620860_622078_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP023602.1_622074_622236_-	NA	NA|106aa|up_6|NZ_CP023602.1_622282_622600_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|595aa|up_5|NZ_CP023602.1_622746_624531_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP023602.1_624426_625434_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP023602.1_625515_626394_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP023602.1_626410_627205_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP023602.1_627201_628242_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP023602.1_628251_629685_-	NA	NA|211aa|down_0|NZ_CP023602.1_631696_632329_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP023602.1_632325_632988_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP023602.1_633008_634358_-	NA	NA|381aa|down_3|NZ_CP023602.1_634369_635512_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP023602.1_635526_635829_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP023602.1_635888_636167_-	NA	NA|418aa|down_6|NZ_CP023602.1_636163_637417_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP023602.1_637536_637923_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP023602.1_637985_638870_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP023602.1_638965_639868_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	4	691985-692061	1	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|136aa|up_9|NZ_CP023602.1_677880_678288_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP023602.1_678347_679034_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP023602.1_679187_681821_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP023602.1_681843_684231_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP023602.1_684368_685091_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP023602.1_685087_685885_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP023602.1_685886_686774_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP023602.1_686779_687994_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_1|NZ_CP023602.1_689017_690463_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|479aa|up_0|NZ_CP023602.1_690459_691896_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023602.1_693196_694747_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023602.1_694798_695191_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023602.1_695187_695445_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023602.1_695627_696863_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023602.1_697113_697527_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023602.1_697523_697760_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023602.1_697863_698370_-	cd00075, HATPase, Histidine kinase-like ATPase domain	NA|157aa|down_7|NZ_CP023602.1_698483_698954_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023602.1_698997_699759_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023602.1_699815_700127_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	5	926581-927528	4	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927364-927399|927364-927399|927364-927399	NZ_CP023602.1_675082-675047|NZ_CP023602.1_1213713-1213748|NZ_CP023602.1_2423705-2423670	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023602.1_931529_932081_-,NA|81aa|down_8|NZ_CP023602.1_937544_937787_+	NA|685aa|up_9|NZ_CP023602.1_914217_916272_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023602.1_916437_917607_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023602.1_917694_918711_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023602.1_918872_919514_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023602.1_919594_920650_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023602.1_920701_921094_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023602.1_921151_921574_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023602.1_921535_921826_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023602.1_921930_922836_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023602.1_922854_923670_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|880aa|down_0|NZ_CP023602.1_927797_930437_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023602.1_930904_931549_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023602.1_931529_932081_-	NA	NA|218aa|down_3|NZ_CP023602.1_932230_932884_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023602.1_932954_933983_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023602.1_934671_935442_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023602.1_935528_936341_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023602.1_936408_937269_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023602.1_937544_937787_+	NA	NA|431aa|down_9|NZ_CP023602.1_938063_939356_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	6	1191280-1191388	2	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023602.1_1180647_1182279_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023602.1_1182354_1183419_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023602.1_1183471_1183945_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023602.1_1183978_1184842_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023602.1_1184846_1185704_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023602.1_1185704_1186787_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023602.1_1186867_1187287_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023602.1_1187398_1187965_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023602.1_1187961_1188357_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023602.1_1188384_1190388_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023602.1_1192473_1194237_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023602.1_1194233_1195007_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023602.1_1195018_1196056_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023602.1_1196242_1197079_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023602.1_1197194_1198046_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023602.1_1198119_1199337_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023602.1_1199389_1200334_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023602.1_1200556_1201624_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023602.1_1201680_1203075_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023602.1_1203276_1203999_+	pfam06271, RDD, RDD family
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	7	1211914-1212770	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	66	1212297-1212318|1212342-1212357|1212480-1212501|1212480-1212501|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615|1212597-1212615	NZ_CP023602.1_2960458-2960437|NZ_CP023602.1_2088599-2088584|NZ_CP023602.1_837394-837415|NZ_CP023602.1_1217608-1217629|NZ_CP023602.1_674746-674728|NZ_CP023602.1_1213440-1213458|NZ_CP023602.1_1217581-1217599|NZ_CP023602.1_1217653-1217671|NZ_CP023602.1_1630671-1630653|NZ_CP023602.1_1633497-1633479|NZ_CP023602.1_1636892-1636874|NZ_CP023602.1_1990809-1990791|NZ_CP023602.1_2061527-2061509|NZ_CP023602.1_2061974-2061956|NZ_CP023602.1_2062073-2062055|NZ_CP023602.1_2802009-2801991|NZ_CP023602.1_2805537-2805519|NZ_CP023602.1_150165-150183|NZ_CP023602.1_333767-333749|NZ_CP023602.1_335186-335168|NZ_CP023602.1_363029-363011|NZ_CP023602.1_443400-443382|NZ_CP023602.1_546744-546726|NZ_CP023602.1_623937-623955|NZ_CP023602.1_624159-624177|NZ_CP023602.1_673912-673894|NZ_CP023602.1_840177-840195|NZ_CP023602.1_1090942-1090960|NZ_CP023602.1_1091590-1091608|NZ_CP023602.1_1095649-1095631|NZ_CP023602.1_1212969-1212987|NZ_CP023602.1_1213359-1213377|NZ_CP023602.1_1218001-1218019|NZ_CP023602.1_1489178-1489160|NZ_CP023602.1_1618635-1618617|NZ_CP023602.1_1619088-1619070|NZ_CP023602.1_1636010-1635992|NZ_CP023602.1_1636019-1636001|NZ_CP023602.1_1864299-1864281|NZ_CP023602.1_1864827-1864809|NZ_CP023602.1_1990083-1990065|NZ_CP023602.1_2001444-2001462|NZ_CP023602.1_2088797-2088779|NZ_CP023602.1_2303475-2303457|NZ_CP023602.1_2356922-2356904|NZ_CP023602.1_2419531-2419549|NZ_CP023602.1_2423618-2423600|NZ_CP023602.1_2569107-2569089|NZ_CP023602.1_2693402-2693420|NZ_CP023602.1_2795324-2795306|NZ_CP023602.1_2795906-2795888|NZ_CP023602.1_3054498-3054516|NZ_CP023602.1_3054597-3054615|NZ_CP023602.1_3705412-3705430|NZ_CP023602.1_3737390-3737372|NZ_CP023602.1_3738014-3737996|NZ_CP023602.1_3738257-3738239|NZ_CP023602.1_3738390-3738372|NZ_CP023602.1_3802253-3802271|NZ_CP023602.1_3802436-3802454|NZ_CP023602.1_3802604-3802622|NZ_CP023602.1_3930402-3930420|NZ_CP023602.1_3932132-3932150|NZ_CP023602.1_3940639-3940657|NZ_CP023602.1_4031617-4031599|NZ_CP023602.1_4094142-4094160	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023602.1_1207346_1207613_+,NA|61aa|down_3|NZ_CP023602.1_1215188_1215371_+,NA|35aa|down_4|NZ_CP023602.1_1215480_1215585_+	NA|465aa|up_9|NZ_CP023602.1_1201680_1203075_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023602.1_1203276_1203999_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023602.1_1204030_1205197_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023602.1_1205267_1205762_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023602.1_1205947_1206382_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023602.1_1206483_1207350_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023602.1_1207346_1207613_+	NA	NA|674aa|up_2|NZ_CP023602.1_1207599_1209621_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023602.1_1209719_1210448_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023602.1_1210558_1211347_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023602.1_1214003_1214324_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023602.1_1214476_1214911_+	pfam00934, PE, PE family	NA|55aa|down_2|NZ_CP023602.1_1215012_1215177_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023602.1_1215188_1215371_+	NA	NA|35aa|down_4|NZ_CP023602.1_1215480_1215585_+	NA	NA|152aa|down_5|NZ_CP023602.1_1215562_1216018_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023602.1_1216432_1218994_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023602.1_1219211_1220150_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023602.1_1220537_1221818_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023602.1_1221922_1222750_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	8	1572153-1573225	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP023602.1_1563916_1564234_+,NA	NA|103aa|up_9|NZ_CP023602.1_1561431_1561740_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023602.1_1561736_1563356_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023602.1_1563916_1564234_+	NA	NA|209aa|up_6|NZ_CP023602.1_1564368_1564995_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023602.1_1565060_1565393_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023602.1_1565408_1566665_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023602.1_1566792_1568004_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023602.1_1568076_1569555_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023602.1_1569551_1570937_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023602.1_1571014_1572049_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023602.1_1574078_1574480_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023602.1_1574476_1574734_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023602.1_1574816_1575776_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023602.1_1575800_1576763_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023602.1_1576896_1577499_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023602.1_1577579_1579547_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023602.1_1579564_1580389_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023602.1_1580557_1581040_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023602.1_1581111_1581936_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023602.1_1582132_1583071_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	9	2088269-2088523	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088350-2088367|2088350-2088367|2088440-2088457	NZ_CP023602.1_401054-401037|NZ_CP023602.1_607392-607375|NZ_CP023602.1_3450112-3450095	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023602.1_2087628_2087892_-,NA	NA|165aa|up_9|NZ_CP023602.1_2073922_2074417_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023602.1_2074820_2075498_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023602.1_2075856_2078682_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023602.1_2078908_2079769_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023602.1_2079809_2080676_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023602.1_2080680_2082567_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023602.1_2082582_2084616_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023602.1_2084735_2086961_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023602.1_2087236_2087632_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023602.1_2087628_2087892_-	NA	NA|346aa|down_0|NZ_CP023602.1_2089660_2090698_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023602.1_2090697_2092065_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023602.1_2092238_2093675_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023602.1_2093710_2095162_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023602.1_2095191_2096142_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023602.1_2096156_2096573_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023602.1_2096850_2097273_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023602.1_2097321_2097624_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023602.1_2097620_2097935_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023602.1_2097934_2099668_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	10	2163362-2163466	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|157aa|up_9|NZ_CP023602.1_2152409_2152880_-,NA|136aa|up_1|NZ_CP023602.1_2159905_2160313_-,NA|127aa|down_6|NZ_CP023602.1_2176534_2176915_-	NA|157aa|up_9|NZ_CP023602.1_2152409_2152880_-	NA	NA|216aa|up_8|NZ_CP023602.1_2153219_2153867_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_7|NZ_CP023602.1_2153873_2156096_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_6|NZ_CP023602.1_2156133_2156577_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_5|NZ_CP023602.1_2156690_2157284_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_4|NZ_CP023602.1_2157366_2157972_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_3|NZ_CP023602.1_2158071_2159076_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_2|NZ_CP023602.1_2159175_2159928_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_1|NZ_CP023602.1_2159905_2160313_-	NA	NA|767aa|up_0|NZ_CP023602.1_2160447_2162748_+	PLN02892, PLN02892, isocitrate lyase	NA|988aa|down_0|NZ_CP023602.1_2167633_2170597_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023602.1_2171045_2171510_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023602.1_2171607_2172471_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023602.1_2172508_2173780_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023602.1_2174051_2175167_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023602.1_2175157_2176498_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023602.1_2176534_2176915_-	NA	NA|621aa|down_7|NZ_CP023602.1_2177071_2178934_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023602.1_2178941_2179421_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023602.1_2179657_2180431_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	11	2168799-2169018	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|157aa|up_9|NZ_CP023602.1_2152409_2152880_-,NA|136aa|up_1|NZ_CP023602.1_2159905_2160313_-,NA|127aa|down_5|NZ_CP023602.1_2176534_2176915_-	NA|157aa|up_9|NZ_CP023602.1_2152409_2152880_-	NA	NA|216aa|up_8|NZ_CP023602.1_2153219_2153867_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_7|NZ_CP023602.1_2153873_2156096_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_6|NZ_CP023602.1_2156133_2156577_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_5|NZ_CP023602.1_2156690_2157284_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_4|NZ_CP023602.1_2157366_2157972_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_3|NZ_CP023602.1_2158071_2159076_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_2|NZ_CP023602.1_2159175_2159928_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_1|NZ_CP023602.1_2159905_2160313_-	NA	NA|767aa|up_0|NZ_CP023602.1_2160447_2162748_+	PLN02892, PLN02892, isocitrate lyase	NA|155aa|down_0|NZ_CP023602.1_2171045_2171510_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023602.1_2171607_2172471_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023602.1_2172508_2173780_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023602.1_2174051_2175167_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023602.1_2175157_2176498_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023602.1_2176534_2176915_-	NA	NA|621aa|down_6|NZ_CP023602.1_2177071_2178934_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023602.1_2178941_2179421_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023602.1_2179657_2180431_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|215aa|down_9|NZ_CP023602.1_2181224_2181869_-	TIGR03085, TIGR03085, TIGR03085 family protein
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	12	3119090-3120444	2,7,6	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-C,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-B,TypeIII-C,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023602.1_3112369_3112624_-,NA|135aa|up_7|NZ_CP023602.1_3112771_3113176_+,NA|64aa|up_6|NZ_CP023602.1_3113172_3113364_+,NA|86aa|up_4|NZ_CP023602.1_3114950_3115208_+,NA|104aa|up_3|NZ_CP023602.1_3115312_3115624_+,NA|203aa|up_2|NZ_CP023602.1_3116043_3116652_+,NA	NA|92aa|up_9|NZ_CP023602.1_3111918_3112194_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023602.1_3112369_3112624_-	NA	NA|135aa|up_7|NZ_CP023602.1_3112771_3113176_+	NA	NA|64aa|up_6|NZ_CP023602.1_3113172_3113364_+	NA	NA|385aa|up_5|NZ_CP023602.1_3113562_3114717_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023602.1_3114950_3115208_+	NA	NA|104aa|up_3|NZ_CP023602.1_3115312_3115624_+	NA	NA|203aa|up_2|NZ_CP023602.1_3116043_3116652_+	NA	NA|470aa|up_1|NZ_CP023602.1_3116722_3118132_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023602.1_3118128_3118941_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023602.1_3120470_3121732_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023602.1_3123529_3123871_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023602.1_3123871_3124888_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023602.1_3124900_3126049_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023602.1_3126144_3127272_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023602.1_3127268_3128177_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023602.1_3128157_3128868_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023602.1_3128877_3129252_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023602.1_3129248_3131687_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023602.1_3131683_3132406_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	13	3121767-3123481	8,7,3	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-B,Type III-C,Type III-D,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGA	36,36,35	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-B,TypeIII-C,TypeIII-D,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023602.1_3112369_3112624_-,NA|135aa|up_8|NZ_CP023602.1_3112771_3113176_+,NA|64aa|up_7|NZ_CP023602.1_3113172_3113364_+,NA|86aa|up_5|NZ_CP023602.1_3114950_3115208_+,NA|104aa|up_4|NZ_CP023602.1_3115312_3115624_+,NA|203aa|up_3|NZ_CP023602.1_3116043_3116652_+,NA	NA|85aa|up_9|NZ_CP023602.1_3112369_3112624_-	NA	NA|135aa|up_8|NZ_CP023602.1_3112771_3113176_+	NA	NA|64aa|up_7|NZ_CP023602.1_3113172_3113364_+	NA	NA|385aa|up_6|NZ_CP023602.1_3113562_3114717_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023602.1_3114950_3115208_+	NA	NA|104aa|up_4|NZ_CP023602.1_3115312_3115624_+	NA	NA|203aa|up_3|NZ_CP023602.1_3116043_3116652_+	NA	NA|470aa|up_2|NZ_CP023602.1_3116722_3118132_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023602.1_3118128_3118941_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023602.1_3120470_3121732_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023602.1_3123529_3123871_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023602.1_3123871_3124888_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023602.1_3124900_3126049_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023602.1_3126144_3127272_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023602.1_3127268_3128177_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023602.1_3128157_3128868_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023602.1_3128877_3129252_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023602.1_3129248_3131687_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023602.1_3131683_3132406_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023602.1_3132805_3133351_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	14	3740584-3741125	8	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023602.1_3755226_3755514_-,NA|87aa|down_9|NZ_CP023602.1_3768634_3768895_-	NA|282aa|up_9|NZ_CP023602.1_3719835_3720681_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023602.1_3721155_3721596_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023602.1_3721629_3722499_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023602.1_3722519_3723530_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023602.1_3723814_3724447_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023602.1_3724513_3725743_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023602.1_3726025_3727375_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023602.1_3727386_3728526_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023602.1_3728522_3729254_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023602.1_3729262_3736834_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023602.1_3743096_3743354_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023602.1_3743609_3753083_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023602.1_3753708_3754155_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023602.1_3754191_3754932_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023602.1_3755226_3755514_-	NA	NA|3717aa|down_5|NZ_CP023602.1_3755850_3767001_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023602.1_3767244_3768039_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023602.1_3768120_3768492_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023602.1_3768389_3768608_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023602.1_3768634_3768895_-	NA
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	15	3948247-3949998	9	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCACCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948838-3948873|3948838-3948873|3948838-3948873|3948838-3948873|3948838-3948873|3949729-3949755|3949729-3949755|3949729-3949755|3949729-3949755	NZ_CP023602.1_3946954-3946989|NZ_CP023602.1_3947296-3947331|NZ_CP023602.1_3947887-3947922|NZ_CP023602.1_3948238-3948273|NZ_CP023602.1_3932687-3932722|NZ_CP023602.1_361969-361995|NZ_CP023602.1_3941140-3941166|NZ_CP023602.1_3941476-3941502|NZ_CP023602.1_3941822-3941848	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023602.1_3953313_3954153_+	NA|318aa|up_9|NZ_CP023602.1_3920978_3921932_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP023602.1_3921956_3922148_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP023602.1_3922362_3923565_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP023602.1_3923589_3924711_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP023602.1_3924781_3926290_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1379aa|up_4|NZ_CP023602.1_3926460_3930597_+	pfam00934, PE, PE family	NA|1902aa|up_3|NZ_CP023602.1_3930887_3936593_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023602.1_3936759_3938307_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023602.1_3938303_3939140_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023602.1_3944974_3945631_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023602.1_3950706_3952353_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023602.1_3952426_3953218_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023602.1_3953313_3954153_+	NA	NA|399aa|down_3|NZ_CP023602.1_3954207_3955404_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023602.1_3955432_3956143_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023602.1_3956207_3957251_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023602.1_3957403_3958315_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023602.1_3958330_3959395_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|344aa|down_8|NZ_CP023602.1_3960637_3961669_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD	NA|175aa|down_9|NZ_CP023602.1_3961682_3962207_-	COG0663, PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]
GCF_002447455.1_ASM244745v1	NZ_CP023602	Mycobacterium tuberculosis strain LE13 chromosome, complete genome	16	4110559-4110647	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023602.1_4101145_4101916_-,NA|119aa|up_3|NZ_CP023602.1_4107050_4107407_+,NA|52aa|up_2|NZ_CP023602.1_4107506_4107662_+,NA|233aa|up_0|NZ_CP023602.1_4109663_4110362_-,NA|126aa|down_6|NZ_CP023602.1_4115882_4116260_+	NA|288aa|up_9|NZ_CP023602.1_4099527_4100391_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023602.1_4101145_4101916_-	NA	NA|549aa|up_7|NZ_CP023602.1_4101912_4103559_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023602.1_4103555_4104419_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023602.1_4104411_4105338_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023602.1_4105339_4106965_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023602.1_4107050_4107407_+	NA	NA|52aa|up_2|NZ_CP023602.1_4107506_4107662_+	NA	NA|652aa|up_1|NZ_CP023602.1_4107672_4109628_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023602.1_4109663_4110362_-	NA	NA|173aa|down_0|NZ_CP023602.1_4110707_4111226_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023602.1_4111226_4112210_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023602.1_4112202_4113396_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023602.1_4113401_4114223_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023602.1_4114354_4115038_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023602.1_4115037_4115775_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023602.1_4115882_4116260_+	NA	NA|225aa|down_7|NZ_CP023602.1_4116358_4117033_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023602.1_4117136_4117931_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023602.1_4117937_4118393_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
