assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	1	366451-367149	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366739-366780|366814-366846	NZ_CP023624.1_374770-374811|NZ_CP023624.1_373585-373617	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP023624.1_363463_363766_+,NA|161aa|down_1|NZ_CP023624.1_376559_377042_-,NA|410aa|down_5|NZ_CP023624.1_379158_380388_+	NA|262aa|up_9|NZ_CP023624.1_358158_358944_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP023624.1_358932_359736_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP023624.1_359745_361143_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP023624.1_361321_363097_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP023624.1_363239_363467_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP023624.1_363463_363766_+	NA	NA|74aa|up_3|NZ_CP023624.1_363813_364035_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP023624.1_364031_364457_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP023624.1_364592_365225_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP023624.1_365221_366130_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP023624.1_375900_376572_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP023624.1_376559_377042_-	NA	NA|239aa|down_2|NZ_CP023624.1_377099_377816_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP023624.1_377917_378574_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP023624.1_378643_379135_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP023624.1_379158_380388_+	NA	NA|621aa|down_6|NZ_CP023624.1_380542_382405_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP023624.1_382476_382863_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP023624.1_382865_383528_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP023624.1_383588_384473_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	2	691898-691974	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP023624.1_677582_677798_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP023624.1_677794_678202_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP023624.1_678261_678948_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP023624.1_679101_681735_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP023624.1_681757_684145_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP023624.1_684282_685005_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP023624.1_685001_685799_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP023624.1_685800_686688_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP023624.1_686693_687908_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP023624.1_688931_690377_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP023624.1_693109_694660_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP023624.1_694711_695104_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP023624.1_695100_695358_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP023624.1_695540_696776_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP023624.1_697026_697440_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP023624.1_697436_697673_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP023624.1_697776_698283_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP023624.1_698396_698867_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP023624.1_698910_699672_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP023624.1_699728_700040_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	3	926494-927441	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927277-927312|927277-927312|927277-927312	NZ_CP023624.1_675001-674966|NZ_CP023624.1_1213614-1213649|NZ_CP023624.1_2423604-2423569	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP023624.1_931451_932003_-,NA|81aa|down_8|NZ_CP023624.1_937466_937709_+	NA|685aa|up_9|NZ_CP023624.1_914130_916185_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP023624.1_916350_917520_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP023624.1_917607_918624_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP023624.1_918785_919427_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP023624.1_919507_920563_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP023624.1_920614_921007_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP023624.1_921064_921487_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP023624.1_921448_921739_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP023624.1_921843_922749_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP023624.1_922767_923583_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP023624.1_927710_930359_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP023624.1_930826_931471_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP023624.1_931451_932003_-	NA	NA|218aa|down_3|NZ_CP023624.1_932152_932806_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP023624.1_932876_933905_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP023624.1_934593_935364_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP023624.1_935450_936263_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP023624.1_936330_937191_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP023624.1_937466_937709_+	NA	NA|431aa|down_9|NZ_CP023624.1_937985_939278_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	4	1191181-1191289	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP023624.1_1180548_1182180_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP023624.1_1182255_1183320_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP023624.1_1183372_1183846_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP023624.1_1183879_1184743_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP023624.1_1184747_1185605_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP023624.1_1185605_1186688_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP023624.1_1186768_1187188_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP023624.1_1187299_1187866_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP023624.1_1187862_1188258_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP023624.1_1188285_1190289_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP023624.1_1192374_1194138_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP023624.1_1194134_1194908_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP023624.1_1194919_1195957_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP023624.1_1196143_1196980_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP023624.1_1197095_1197947_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP023624.1_1198020_1199238_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP023624.1_1199290_1200235_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP023624.1_1200457_1201525_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP023624.1_1201581_1202976_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP023624.1_1203177_1203900_+	pfam06271, RDD, RDD family
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	5	1211815-1212671	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	70	1212198-1212219|1212243-1212258|1212381-1212402|1212381-1212402|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516|1212498-1212516	NZ_CP023624.1_2960370-2960349|NZ_CP023624.1_2088483-2088468|NZ_CP023624.1_837306-837327|NZ_CP023624.1_1217509-1217530|NZ_CP023624.1_674665-674647|NZ_CP023624.1_1213341-1213359|NZ_CP023624.1_1217482-1217500|NZ_CP023624.1_1217554-1217572|NZ_CP023624.1_1630567-1630549|NZ_CP023624.1_1633393-1633375|NZ_CP023624.1_1990687-1990669|NZ_CP023624.1_2061411-2061393|NZ_CP023624.1_2061858-2061840|NZ_CP023624.1_2061957-2061939|NZ_CP023624.1_2801919-2801901|NZ_CP023624.1_2805447-2805429|NZ_CP023624.1_1636788-1636770|NZ_CP023624.1_150188-150206|NZ_CP023624.1_333788-333770|NZ_CP023624.1_335207-335189|NZ_CP023624.1_335660-335642|NZ_CP023624.1_335711-335693|NZ_CP023624.1_335720-335702|NZ_CP023624.1_337991-337973|NZ_CP023624.1_338120-338102|NZ_CP023624.1_338387-338369|NZ_CP023624.1_338416-338434|NZ_CP023624.1_338510-338492|NZ_CP023624.1_363041-363023|NZ_CP023624.1_443370-443352|NZ_CP023624.1_546702-546684|NZ_CP023624.1_623892-623910|NZ_CP023624.1_624114-624132|NZ_CP023624.1_673831-673813|NZ_CP023624.1_840089-840107|NZ_CP023624.1_1090861-1090879|NZ_CP023624.1_1091509-1091527|NZ_CP023624.1_1095567-1095549|NZ_CP023624.1_1212870-1212888|NZ_CP023624.1_1213260-1213278|NZ_CP023624.1_1217902-1217920|NZ_CP023624.1_1489077-1489059|NZ_CP023624.1_1618530-1618512|NZ_CP023624.1_1618983-1618965|NZ_CP023624.1_1635906-1635888|NZ_CP023624.1_1635915-1635897|NZ_CP023624.1_1864179-1864161|NZ_CP023624.1_1864707-1864689|NZ_CP023624.1_1989961-1989943|NZ_CP023624.1_2001323-2001341|NZ_CP023624.1_2088681-2088663|NZ_CP023624.1_2303379-2303361|NZ_CP023624.1_2356831-2356813|NZ_CP023624.1_2419430-2419448|NZ_CP023624.1_2423517-2423499|NZ_CP023624.1_2569011-2568993|NZ_CP023624.1_2693310-2693328|NZ_CP023624.1_2795234-2795216|NZ_CP023624.1_2795816-2795798|NZ_CP023624.1_3054406-3054424|NZ_CP023624.1_3054505-3054523|NZ_CP023624.1_3705320-3705338|NZ_CP023624.1_3802159-3802177|NZ_CP023624.1_3802342-3802360|NZ_CP023624.1_3802510-3802528|NZ_CP023624.1_3930333-3930351|NZ_CP023624.1_3932063-3932081|NZ_CP023624.1_3940570-3940588|NZ_CP023624.1_4031543-4031525|NZ_CP023624.1_4094063-4094081	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP023624.1_1207247_1207514_+,NA|61aa|down_3|NZ_CP023624.1_1215089_1215272_+,NA|35aa|down_4|NZ_CP023624.1_1215381_1215486_+	NA|465aa|up_9|NZ_CP023624.1_1201581_1202976_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP023624.1_1203177_1203900_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP023624.1_1203931_1205098_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP023624.1_1205168_1205663_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP023624.1_1205848_1206283_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP023624.1_1206384_1207251_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP023624.1_1207247_1207514_+	NA	NA|674aa|up_2|NZ_CP023624.1_1207500_1209522_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP023624.1_1209620_1210349_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP023624.1_1210459_1211248_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP023624.1_1213904_1214225_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP023624.1_1214377_1214812_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP023624.1_1214910_1215078_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP023624.1_1215089_1215272_+	NA	NA|35aa|down_4|NZ_CP023624.1_1215381_1215486_+	NA	NA|152aa|down_5|NZ_CP023624.1_1215463_1215919_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP023624.1_1216333_1218895_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP023624.1_1219112_1220051_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP023624.1_1220438_1221719_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP023624.1_1221823_1222651_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	6	1572053-1573125	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP023624.1_1563816_1564134_+,NA	NA|103aa|up_9|NZ_CP023624.1_1561331_1561640_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP023624.1_1561636_1563256_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP023624.1_1563816_1564134_+	NA	NA|209aa|up_6|NZ_CP023624.1_1564268_1564895_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP023624.1_1564960_1565293_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP023624.1_1565308_1566565_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP023624.1_1566692_1567904_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP023624.1_1567976_1569455_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP023624.1_1569451_1570837_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP023624.1_1570914_1571949_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP023624.1_1573979_1574381_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP023624.1_1574377_1574635_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP023624.1_1574717_1575677_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP023624.1_1575701_1576664_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP023624.1_1576797_1577400_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP023624.1_1577480_1579448_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP023624.1_1579465_1580290_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP023624.1_1580458_1580941_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP023624.1_1581012_1581837_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP023624.1_1582033_1582972_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	7	2088153-2088407	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088234-2088251|2088234-2088251|2088324-2088341	NZ_CP023624.1_401066-401049|NZ_CP023624.1_607347-607330|NZ_CP023624.1_3450020-3450003	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP023624.1_2087512_2087776_-,NA	NA|165aa|up_9|NZ_CP023624.1_2073806_2074301_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP023624.1_2074704_2075382_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP023624.1_2075740_2078566_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP023624.1_2078792_2079653_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP023624.1_2079693_2080560_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP023624.1_2080564_2082451_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP023624.1_2082466_2084500_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP023624.1_2084619_2086845_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP023624.1_2087120_2087516_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP023624.1_2087512_2087776_-	NA	NA|346aa|down_0|NZ_CP023624.1_2089544_2090582_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP023624.1_2090581_2091949_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP023624.1_2092122_2093559_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP023624.1_2093594_2095046_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP023624.1_2095075_2096026_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP023624.1_2096040_2096457_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP023624.1_2096734_2097157_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP023624.1_2097205_2097508_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP023624.1_2097504_2097819_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP023624.1_2097818_2099552_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	8	2163245-2163349	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023624.1_2159789_2160197_-,NA|127aa|down_6|NZ_CP023624.1_2176416_2176797_-	NA|216aa|up_9|NZ_CP023624.1_2153103_2153751_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023624.1_2153757_2155980_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023624.1_2156017_2156461_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023624.1_2156574_2157168_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023624.1_2157250_2157856_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023624.1_2157955_2158960_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023624.1_2159059_2159812_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023624.1_2159789_2160197_-	NA	NA|368aa|up_1|NZ_CP023624.1_2160331_2161435_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023624.1_2161434_2162631_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP023624.1_2167515_2170479_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP023624.1_2170927_2171392_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP023624.1_2171489_2172353_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP023624.1_2172390_2173662_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP023624.1_2173933_2175049_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP023624.1_2175039_2176380_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP023624.1_2176416_2176797_-	NA	NA|621aa|down_7|NZ_CP023624.1_2176953_2178816_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP023624.1_2178823_2179303_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP023624.1_2179539_2180313_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	9	2168681-2168900	7	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP023624.1_2159789_2160197_-,NA|127aa|down_5|NZ_CP023624.1_2176416_2176797_-	NA|216aa|up_9|NZ_CP023624.1_2153103_2153751_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP023624.1_2153757_2155980_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP023624.1_2156017_2156461_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP023624.1_2156574_2157168_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP023624.1_2157250_2157856_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP023624.1_2157955_2158960_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP023624.1_2159059_2159812_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP023624.1_2159789_2160197_-	NA	NA|368aa|up_1|NZ_CP023624.1_2160331_2161435_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP023624.1_2161434_2162631_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|155aa|down_0|NZ_CP023624.1_2170927_2171392_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP023624.1_2171489_2172353_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP023624.1_2172390_2173662_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP023624.1_2173933_2175049_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP023624.1_2175039_2176380_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP023624.1_2176416_2176797_-	NA	NA|621aa|down_6|NZ_CP023624.1_2176953_2178816_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP023624.1_2178823_2179303_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP023624.1_2179539_2180313_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP023624.1_2180316_2181084_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	10	3118997-3120351	1,8,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP023624.1_3112276_3112531_-,NA|135aa|up_7|NZ_CP023624.1_3112678_3113083_+,NA|64aa|up_6|NZ_CP023624.1_3113079_3113271_+,NA|86aa|up_4|NZ_CP023624.1_3114857_3115115_+,NA|104aa|up_3|NZ_CP023624.1_3115219_3115531_+,NA|203aa|up_2|NZ_CP023624.1_3115950_3116559_+,NA	NA|92aa|up_9|NZ_CP023624.1_3111825_3112101_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP023624.1_3112276_3112531_-	NA	NA|135aa|up_7|NZ_CP023624.1_3112678_3113083_+	NA	NA|64aa|up_6|NZ_CP023624.1_3113079_3113271_+	NA	NA|385aa|up_5|NZ_CP023624.1_3113469_3114624_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP023624.1_3114857_3115115_+	NA	NA|104aa|up_3|NZ_CP023624.1_3115219_3115531_+	NA	NA|203aa|up_2|NZ_CP023624.1_3115950_3116559_+	NA	NA|470aa|up_1|NZ_CP023624.1_3116629_3118039_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP023624.1_3118035_3118848_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP023624.1_3120377_3121639_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP023624.1_3123436_3123778_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP023624.1_3123778_3124795_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP023624.1_3124807_3125956_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP023624.1_3126051_3127179_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP023624.1_3127175_3128084_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP023624.1_3128064_3128775_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP023624.1_3128784_3129159_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP023624.1_3129155_3131594_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP023624.1_3131590_3132313_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	11	3121674-3123388	9,4,2	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP023624.1_3112276_3112531_-,NA|135aa|up_8|NZ_CP023624.1_3112678_3113083_+,NA|64aa|up_7|NZ_CP023624.1_3113079_3113271_+,NA|86aa|up_5|NZ_CP023624.1_3114857_3115115_+,NA|104aa|up_4|NZ_CP023624.1_3115219_3115531_+,NA|203aa|up_3|NZ_CP023624.1_3115950_3116559_+,NA	NA|85aa|up_9|NZ_CP023624.1_3112276_3112531_-	NA	NA|135aa|up_8|NZ_CP023624.1_3112678_3113083_+	NA	NA|64aa|up_7|NZ_CP023624.1_3113079_3113271_+	NA	NA|385aa|up_6|NZ_CP023624.1_3113469_3114624_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP023624.1_3114857_3115115_+	NA	NA|104aa|up_4|NZ_CP023624.1_3115219_3115531_+	NA	NA|203aa|up_3|NZ_CP023624.1_3115950_3116559_+	NA	NA|470aa|up_2|NZ_CP023624.1_3116629_3118039_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP023624.1_3118035_3118848_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP023624.1_3120377_3121639_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP023624.1_3123436_3123778_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP023624.1_3123778_3124795_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP023624.1_3124807_3125956_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP023624.1_3126051_3127179_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP023624.1_3127175_3128084_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP023624.1_3128064_3128775_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP023624.1_3128784_3129159_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP023624.1_3129155_3131594_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP023624.1_3131590_3132313_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP023624.1_3132712_3133258_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	12	3736985-3738753	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCGCCGNNGCCGCCGNNGCCG	22	1	1	3738445-3738473	NZ_CP023624.1_1190833-1190861	NA	18	18	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023624.1_3755133_3755421_-,NA|87aa|down_9|NZ_CP023624.1_3768541_3768802_-	NA|282aa|up_9|NZ_CP023624.1_3719742_3720588_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023624.1_3721062_3721503_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023624.1_3721536_3722406_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023624.1_3722426_3723437_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023624.1_3723721_3724354_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023624.1_3724420_3725650_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023624.1_3725932_3727282_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023624.1_3727293_3728433_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023624.1_3728429_3729161_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023624.1_3729169_3736741_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023624.1_3743003_3743261_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023624.1_3743516_3752990_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023624.1_3753615_3754062_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023624.1_3754098_3754839_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023624.1_3755133_3755421_-	NA	NA|3717aa|down_5|NZ_CP023624.1_3755757_3766908_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023624.1_3767151_3767946_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023624.1_3768027_3768399_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023624.1_3768296_3768515_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023624.1_3768541_3768802_-	NA
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	13	3740491-3741032	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP023624.1_3755133_3755421_-,NA|87aa|down_9|NZ_CP023624.1_3768541_3768802_-	NA|282aa|up_9|NZ_CP023624.1_3719742_3720588_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP023624.1_3721062_3721503_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP023624.1_3721536_3722406_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP023624.1_3722426_3723437_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP023624.1_3723721_3724354_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP023624.1_3724420_3725650_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP023624.1_3725932_3727282_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP023624.1_3727293_3728433_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP023624.1_3728429_3729161_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP023624.1_3729169_3736741_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP023624.1_3743003_3743261_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP023624.1_3743516_3752990_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP023624.1_3753615_3754062_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP023624.1_3754098_3754839_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP023624.1_3755133_3755421_-	NA	NA|3717aa|down_5|NZ_CP023624.1_3755757_3766908_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP023624.1_3767151_3767946_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP023624.1_3768027_3768399_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP023624.1_3768296_3768515_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP023624.1_3768541_3768802_-	NA
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	14	3948177-3949928	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CANCGGCGGCANCGGCGGCNNCGGCGGNNNCGGCGG	36	2	9	3948768-3948803|3948768-3948803|3948768-3948803|3948768-3948803|3948768-3948803|3949659-3949685|3949659-3949685|3949659-3949685|3949659-3949685	NZ_CP023624.1_3946884-3946919|NZ_CP023624.1_3947226-3947261|NZ_CP023624.1_3947817-3947852|NZ_CP023624.1_3948168-3948203|NZ_CP023624.1_3932618-3932653|NZ_CP023624.1_361981-362007|NZ_CP023624.1_3941071-3941097|NZ_CP023624.1_3941407-3941433|NZ_CP023624.1_3941753-3941779	NA	21	21	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP023624.1_3953243_3954083_+	NA|318aa|up_9|NZ_CP023624.1_3920891_3921845_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP023624.1_3921869_3922061_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP023624.1_3922275_3923478_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP023624.1_3923502_3924624_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP023624.1_3924694_3926203_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1385aa|up_4|NZ_CP023624.1_3926373_3930528_+	pfam00934, PE, PE family	NA|1902aa|up_3|NZ_CP023624.1_3930818_3936524_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP023624.1_3936690_3938238_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP023624.1_3938234_3939071_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP023624.1_3944904_3945561_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP023624.1_3950636_3952283_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP023624.1_3952356_3953148_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP023624.1_3953243_3954083_+	NA	NA|399aa|down_3|NZ_CP023624.1_3954137_3955334_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP023624.1_3955362_3956073_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP023624.1_3956137_3957181_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP023624.1_3957333_3958245_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP023624.1_3958260_3959325_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP023624.1_3959341_3960526_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP023624.1_3960567_3961599_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002447895.1_ASM244789v1	NZ_CP023624	Mycobacterium tuberculosis strain MDRMA701 chromosome, complete genome	15	4110480-4110568	10	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP023624.1_4101066_4101837_-,NA|119aa|up_3|NZ_CP023624.1_4106971_4107328_+,NA|52aa|up_2|NZ_CP023624.1_4107427_4107583_+,NA|233aa|up_0|NZ_CP023624.1_4109584_4110283_-,NA|126aa|down_6|NZ_CP023624.1_4115803_4116181_+	NA|288aa|up_9|NZ_CP023624.1_4099448_4100312_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP023624.1_4101066_4101837_-	NA	NA|549aa|up_7|NZ_CP023624.1_4101833_4103480_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP023624.1_4103476_4104340_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP023624.1_4104332_4105259_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP023624.1_4105260_4106886_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP023624.1_4106971_4107328_+	NA	NA|52aa|up_2|NZ_CP023624.1_4107427_4107583_+	NA	NA|652aa|up_1|NZ_CP023624.1_4107593_4109549_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP023624.1_4109584_4110283_-	NA	NA|173aa|down_0|NZ_CP023624.1_4110628_4111147_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP023624.1_4111147_4112131_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP023624.1_4112123_4113317_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP023624.1_4113322_4114144_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP023624.1_4114275_4114959_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP023624.1_4114958_4115696_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP023624.1_4115803_4116181_+	NA	NA|225aa|down_7|NZ_CP023624.1_4116279_4116954_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP023624.1_4117059_4117854_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP023624.1_4117860_4118316_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
