assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	1	316919-317000	1	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CACGCCGCGGTTCGTCTCCTCCAGCTCG	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|398aa|up_8|NZ_CP023298.1_301979_303173_-,NA|230aa|up_6|NZ_CP023298.1_305624_306314_-,NA|501aa|up_5|NZ_CP023298.1_306343_307846_-,NA|77aa|down_6|NZ_CP023298.1_321445_321676_+	NA|411aa|up_9|NZ_CP023298.1_300747_301980_-	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|398aa|up_8|NZ_CP023298.1_301979_303173_-	NA	NA|658aa|up_7|NZ_CP023298.1_303455_305429_-	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed	NA|230aa|up_6|NZ_CP023298.1_305624_306314_-	NA	NA|501aa|up_5|NZ_CP023298.1_306343_307846_-	NA	NA|229aa|up_4|NZ_CP023298.1_307842_308529_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|179aa|up_3|NZ_CP023298.1_308525_309062_-	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|764aa|up_2|NZ_CP023298.1_309162_311454_+	pfam13861, FLgD_tudor, FlgD Tudor-like domain	NA|1041aa|up_1|NZ_CP023298.1_311480_314603_+	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	NA|525aa|up_0|NZ_CP023298.1_314609_316184_-	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|344aa|down_0|NZ_CP023298.1_317526_318558_-	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains	NA|135aa|down_1|NZ_CP023298.1_318554_318959_-	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains	NA|142aa|down_2|NZ_CP023298.1_318955_319381_-	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation	NA|287aa|down_3|NZ_CP023298.1_319382_320243_-	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation	NA|118aa|down_4|NZ_CP023298.1_320409_320763_+	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|156aa|down_5|NZ_CP023298.1_320872_321340_+	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL	NA|77aa|down_6|NZ_CP023298.1_321445_321676_+	NA	NA|263aa|down_7|NZ_CP023298.1_321754_322543_-	COG5660, COG5660, Predicted integral membrane protein [Function unknown]	NA|208aa|down_8|NZ_CP023298.1_322593_323217_-	pfam11706, zf-CGNR, CGNR zinc finger	NA|262aa|down_9|NZ_CP023298.1_323355_324141_+	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	2	701371-701477	2	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGGCAGCGTGGGTGGCTGGCGTGGTC	27	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|133aa|up_2|NZ_CP023298.1_697288_697687_-,NA|288aa|down_2|NZ_CP023298.1_703320_704184_+	NA|531aa|up_9|NZ_CP023298.1_689388_690981_+	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]	NA|152aa|up_8|NZ_CP023298.1_690977_691433_+	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains	NA|273aa|up_7|NZ_CP023298.1_691425_692244_+	cd01517, PAP_phosphatase, PAP-phosphatase_like domains	NA|258aa|up_6|NZ_CP023298.1_692312_693086_+	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|337aa|up_5|NZ_CP023298.1_693237_694248_+	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning]	NA|640aa|up_4|NZ_CP023298.1_694508_696428_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|242aa|up_3|NZ_CP023298.1_696464_697190_+	cd05233, SDR_c, classical (c) SDRs	NA|133aa|up_2|NZ_CP023298.1_697288_697687_-	NA	NA|709aa|up_1|NZ_CP023298.1_697998_700125_+	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair]	NA|166aa|up_0|NZ_CP023298.1_700558_701056_-	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain	NA|102aa|down_0|NZ_CP023298.1_702511_702817_+	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156	NA|71aa|down_1|NZ_CP023298.1_702878_703091_+	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism]	NA|288aa|down_2|NZ_CP023298.1_703320_704184_+	NA	NA|381aa|down_3|NZ_CP023298.1_704169_705312_-	pfam13679, Methyltransf_32, Methyltransferase domain	NA|649aa|down_4|NZ_CP023298.1_706539_708486_-	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]	NA|75aa|down_5|NZ_CP023298.1_708702_708927_-	pfam11305, DUF3107, Protein of unknown function (DUF3107)	NA|220aa|down_6|NZ_CP023298.1_708966_709626_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|521aa|down_7|NZ_CP023298.1_710066_711629_+	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|320aa|down_8|NZ_CP023298.1_711628_712588_+	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold	NA|294aa|down_9|NZ_CP023298.1_712639_713521_+	pfam11350, DUF3152, Protein of unknown function (DUF3152)
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	3	737747-737849	3	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGTGACCGGTCCTGCTCCGACCC	25	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|302aa|up_7|NZ_CP023298.1_729574_730480_-,NA	NA|179aa|up_9|NZ_CP023298.1_727721_728258_+	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB	NA|434aa|up_8|NZ_CP023298.1_728268_729570_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|302aa|up_7|NZ_CP023298.1_729574_730480_-	NA	NA|179aa|up_6|NZ_CP023298.1_730479_731016_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|207aa|up_5|NZ_CP023298.1_731080_731701_+	pfam00329, Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit	NA|320aa|up_4|NZ_CP023298.1_731700_732660_+	pfam00146, NADHdh, NADH dehydrogenase	NA|200aa|up_3|NZ_CP023298.1_732762_733362_+	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI	NA|190aa|up_2|NZ_CP023298.1_733358_733928_+	pfam00499, Oxidored_q3, NADH-ubiquinone/plastoquinone oxidoreductase chain 6	NA|119aa|up_1|NZ_CP023298.1_733927_734284_+	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK	NA|638aa|up_0|NZ_CP023298.1_734280_736194_+	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed	NA|485aa|down_0|NZ_CP023298.1_737904_739359_+	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN	NA|302aa|down_1|NZ_CP023298.1_739771_740677_+	PRK03072, PRK03072, heat shock protein HtpX; Provisional	NA|142aa|down_2|NZ_CP023298.1_740930_741356_+	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|336aa|down_3|NZ_CP023298.1_741412_742420_+	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1	NA|271aa|down_4|NZ_CP023298.1_742439_743252_+	COG3393, COG3393, Predicted acetyltransferase [General function prediction only]	NA|203aa|down_5|NZ_CP023298.1_743296_743905_+	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown]	NA|101aa|down_6|NZ_CP023298.1_743926_744229_+	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase	NA|186aa|down_7|NZ_CP023298.1_744687_745245_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|330aa|down_8|NZ_CP023298.1_747348_748338_+	pfam01636, APH, Phosphotransferase enzyme family	NA|164aa|down_9|NZ_CP023298.1_749000_749492_+	cd11740, YajQ_like, Proteins similar to Escherichia coli YajQ
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	4	1175224-1175385	1	CRT	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTCGGCTCGCCGGCAGCC	18	0	0	NA	NA	NA	4	4	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|111aa|down_2|NZ_CP023298.1_1177149_1177482_+,NA|350aa|down_4|NZ_CP023298.1_1177914_1178964_+,NA|470aa|down_5|NZ_CP023298.1_1178960_1180370_+	NA|262aa|up_9|NZ_CP023298.1_1161697_1162483_-	pfam06750, DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain	NA|169aa|up_8|NZ_CP023298.1_1162637_1163144_-	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]	NA|412aa|up_7|NZ_CP023298.1_1163246_1164482_-	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]	NA|374aa|up_6|NZ_CP023298.1_1164484_1165606_-	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]	NA|556aa|up_5|NZ_CP023298.1_1165686_1167354_-	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB	NA|324aa|up_4|NZ_CP023298.1_1167413_1168385_-	PRK09393, ftrA, transcriptional activator FtrA; Provisional	NA|428aa|up_3|NZ_CP023298.1_1168438_1169722_+	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters	NA|105aa|up_2|NZ_CP023298.1_1169835_1170150_-	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation	NA|807aa|up_1|NZ_CP023298.1_1170244_1172665_+	pfam13424, TPR_12, Tetratricopeptide repeat	NA|560aa|up_0|NZ_CP023298.1_1172666_1174346_-	cd01948, EAL, EAL domain	NA|46aa|down_0|NZ_CP023298.1_1176277_1176415_-	TIGR04268, FxSxx-COOH, FXSXX-COOH protein	NA|158aa|down_1|NZ_CP023298.1_1176626_1177100_+	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family	NA|111aa|down_2|NZ_CP023298.1_1177149_1177482_+	NA	NA|95aa|down_3|NZ_CP023298.1_1177502_1177787_-	pfam04248, NTP_transf_9, Domain of unknown function (DUF427)	NA|350aa|down_4|NZ_CP023298.1_1177914_1178964_+	NA	NA|470aa|down_5|NZ_CP023298.1_1178960_1180370_+	NA	NA|596aa|down_6|NZ_CP023298.1_1180571_1182359_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|281aa|down_7|NZ_CP023298.1_1182937_1183780_-	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal	NA|337aa|down_8|NZ_CP023298.1_1184337_1185348_-	pfam14350, Beta_protein, Beta protein	NA|432aa|down_9|NZ_CP023298.1_1185384_1186680_-	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	5	1847622-1847697	4	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CTCGTCGTCCGCCGCTGATCGTCTT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|225aa|up_8|NZ_CP023298.1_1831653_1832328_-,NA	NA|193aa|up_9|NZ_CP023298.1_1831078_1831657_-	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase	NA|225aa|up_8|NZ_CP023298.1_1831653_1832328_-	NA	NA|268aa|up_7|NZ_CP023298.1_1832324_1833128_-	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs	NA|650aa|up_6|NZ_CP023298.1_1833213_1835163_+	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism]	NA|353aa|up_5|NZ_CP023298.1_1836527_1837586_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|148aa|up_4|NZ_CP023298.1_1838824_1839268_+	pfam18726, HEPN_SAV_6107, SAV_6107-like HEPN	NA|569aa|up_3|NZ_CP023298.1_1841250_1842957_+	cd03468, PolY_like, DNA Polymerase Y-family	NA|1135aa|up_2|NZ_CP023298.1_1842969_1846374_+	PRK05672, dnaE2, error-prone DNA polymerase; Validated	NA|125aa|up_1|NZ_CP023298.1_1846416_1846791_+	pfam00720, SSI, Subtilisin inhibitor-like	NA|249aa|up_0|NZ_CP023298.1_1846840_1847587_+	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA|131aa|down_0|NZ_CP023298.1_1849128_1849521_+	pfam11239, DUF3040, Protein of unknown function (DUF3040)	NA|822aa|down_1|NZ_CP023298.1_1850183_1852649_-	pfam01841, Transglut_core, Transglutaminase-like superfamily	NA|433aa|down_2|NZ_CP023298.1_1852645_1853944_-	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]	NA|346aa|down_3|NZ_CP023298.1_1853946_1854984_-	COG0714, COG0714, MoxR-like ATPases [General function prediction only]	NA|929aa|down_4|NZ_CP023298.1_1855394_1858181_+	PRK00390, leuS, leucyl-tRNA synthetase; Validated	NA|238aa|down_5|NZ_CP023298.1_1858339_1859053_-	COG0398, COG0398, Uncharacterized conserved protein [Function unknown]	NA|238aa|down_6|NZ_CP023298.1_1859114_1859828_-	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only]	NA|407aa|down_7|NZ_CP023298.1_1859843_1861064_-	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]	NA|266aa|down_8|NZ_CP023298.1_1861667_1862465_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|144aa|down_9|NZ_CP023298.1_1863299_1863731_+	PRK00326, PRK00326, transcriptional regulator MraZ
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	6	2214153-2214234	5	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCCGTGATCGATGCGCTGCGGGGCTGAA	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|52aa|up_9|NZ_CP023298.1_2202086_2202242_-,NA|202aa|up_6|NZ_CP023298.1_2203400_2204006_+,NA|154aa|up_5|NZ_CP023298.1_2204067_2204529_+,NA|347aa|up_4|NZ_CP023298.1_2204621_2205662_+,NA|129aa|down_0|NZ_CP023298.1_2214564_2214951_+,NA|261aa|down_2|NZ_CP023298.1_2216887_2217670_-,NA|166aa|down_9|NZ_CP023298.1_2224002_2224500_-	NA|52aa|up_9|NZ_CP023298.1_2202086_2202242_-	NA	NA|195aa|up_8|NZ_CP023298.1_2202240_2202825_+	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit	NA|115aa|up_7|NZ_CP023298.1_2203039_2203384_+	COG1378, COG1378, Predicted transcriptional regulators [Transcription]	NA|202aa|up_6|NZ_CP023298.1_2203400_2204006_+	NA	NA|154aa|up_5|NZ_CP023298.1_2204067_2204529_+	NA	NA|347aa|up_4|NZ_CP023298.1_2204621_2205662_+	NA	NA|259aa|up_3|NZ_CP023298.1_2205906_2206683_-	pfam13539, Peptidase_M15_4, D-alanyl-D-alanine carboxypeptidase	NA|1690aa|up_2|NZ_CP023298.1_2206959_2212029_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|97aa|up_1|NZ_CP023298.1_2212233_2212524_+	pfam10825, DUF2752, Protein of unknown function (DUF2752)	NA|180aa|up_0|NZ_CP023298.1_2212538_2213078_+	pfam06271, RDD, RDD family	NA|129aa|down_0|NZ_CP023298.1_2214564_2214951_+	NA	NA|424aa|down_1|NZ_CP023298.1_2215619_2216891_-	PLN02856, PLN02856, fumarylacetoacetase	NA|261aa|down_2|NZ_CP023298.1_2216887_2217670_-	NA	NA|392aa|down_3|NZ_CP023298.1_2217864_2219040_-	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|367aa|down_4|NZ_CP023298.1_2219355_2220456_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|399aa|down_5|NZ_CP023298.1_2220406_2221603_-	PRK07337, PRK07337, pyridoxal phosphate-dependent aminotransferase	NA|201aa|down_6|NZ_CP023298.1_2221843_2222446_+	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|159aa|down_7|NZ_CP023298.1_2222482_2222959_-	pfam08044, DUF1707, Domain of unknown function (DUF1707)	NA|267aa|down_8|NZ_CP023298.1_2223205_2224006_+	TIGR02764, Probable_polysaccharide_deacetylase_PdaB, polysaccharide deacetylase family sporulation protein PdaB	NA|166aa|down_9|NZ_CP023298.1_2224002_2224500_-	NA
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	7	2648302-2648490	6	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCGGGTCGGCGGCGGACTCGCGCCCGA	27	0	0	NA	NA	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA	NA|535aa|up_9|NZ_CP023298.1_2636265_2637870_-	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]	NA|397aa|up_8|NZ_CP023298.1_2637874_2639065_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|385aa|up_7|NZ_CP023298.1_2639263_2640418_+	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains	NA|129aa|up_6|NZ_CP023298.1_2640471_2640858_+	pfam01627, Hpt, Hpt domain	NA|384aa|up_5|NZ_CP023298.1_2640866_2642018_-	TIGR02635, putative_xylose_isomerase, L-rhamnose isomerase, Streptomyces subtype	NA|344aa|up_4|NZ_CP023298.1_2642014_2643046_-	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins	NA|319aa|up_3|NZ_CP023298.1_2643042_2643999_-	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins	NA|500aa|up_2|NZ_CP023298.1_2643995_2645495_-	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]	NA|343aa|up_1|NZ_CP023298.1_2645499_2646528_-	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs	NA|140aa|up_0|NZ_CP023298.1_2647275_2647695_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|287aa|down_0|NZ_CP023298.1_2649176_2650037_+	pfam12277, DUF3618, Protein of unknown function (DUF3618)	NA|309aa|down_1|NZ_CP023298.1_2650158_2651085_-	pfam00459, Inositol_P, Inositol monophosphatase family	NA|527aa|down_2|NZ_CP023298.1_2651083_2652664_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|200aa|down_3|NZ_CP023298.1_2652644_2653244_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|443aa|down_4|NZ_CP023298.1_2653301_2654630_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|497aa|down_5|NZ_CP023298.1_2654690_2656181_+	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2	NA|445aa|down_6|NZ_CP023298.1_2656192_2657527_+	PRK06062, PRK06062, hypothetical protein; Provisional	NA|479aa|down_7|NZ_CP023298.1_2657658_2659095_+	PRK13473, PRK13473, aminobutyraldehyde dehydrogenase	NA|386aa|down_8|NZ_CP023298.1_2659145_2660303_+	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|403aa|down_9|NZ_CP023298.1_2660344_2661553_+	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	8	2931992-2932076	7	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCGGTGTCTGAGCCCGGTGTCTG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|89aa|up_0|NZ_CP023298.1_2929130_2929397_-,NA|315aa|down_2|NZ_CP023298.1_2935043_2935988_-,NA|74aa|down_3|NZ_CP023298.1_2935991_2936213_-	NA|640aa|up_9|NZ_CP023298.1_2913142_2915062_+	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR	NA|635aa|up_8|NZ_CP023298.1_2915283_2917188_+	COG1620, LldP, L-lactate permease [Energy production and conversion]	NA|532aa|up_7|NZ_CP023298.1_2917276_2918872_+	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]	NA|144aa|up_6|NZ_CP023298.1_2919265_2919697_-	cd00161, RICIN, Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication	NA|434aa|up_5|NZ_CP023298.1_2921028_2922330_-	pfam00872, Transposase_mut, Transposase, Mutator family	NA|888aa|up_4|NZ_CP023298.1_2922482_2925146_-	TIGR03788, marine_srt_targ, marine proteobacterial sortase target protein	NA|220aa|up_3|NZ_CP023298.1_2925142_2925802_-	COG0789, SoxR, Predicted transcriptional regulators [Transcription]	NA|245aa|up_2|NZ_CP023298.1_2925822_2926557_+	pfam04199, Cyclase, Putative cyclase	NA|767aa|up_1|NZ_CP023298.1_2926526_2928827_-	pfam05547, Peptidase_M6, Immune inhibitor A peptidase M6	NA|89aa|up_0|NZ_CP023298.1_2929130_2929397_-	NA	NA|383aa|down_0|NZ_CP023298.1_2932394_2933543_-	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19)	NA|365aa|down_1|NZ_CP023298.1_2933673_2934768_+	COG4124, ManB, Beta-mannanase [Carbohydrate transport and metabolism]	NA|315aa|down_2|NZ_CP023298.1_2935043_2935988_-	NA	NA|74aa|down_3|NZ_CP023298.1_2935991_2936213_-	NA	NA|647aa|down_4|NZ_CP023298.1_2936268_2938209_-	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]	NA|543aa|down_5|NZ_CP023298.1_2938348_2939977_+	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed	NA|349aa|down_6|NZ_CP023298.1_2940040_2941087_+	pfam06224, HTH_42, Winged helix DNA-binding domain	NA|437aa|down_7|NZ_CP023298.1_2941187_2942498_+	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD)	NA|186aa|down_8|NZ_CP023298.1_2942647_2943205_-	pfam01872, RibD_C, RibD C-terminal domain	NA|641aa|down_9|NZ_CP023298.1_2943533_2945456_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	9	3451720-3451872	8	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCTGCCGCGGAGGCCGAGCGGCAGCGG	27	0	0	NA	NA	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|342aa|up_8|NZ_CP023298.1_3434004_3435030_-,NA|323aa|up_2|NZ_CP023298.1_3445610_3446579_+,NA	NA|749aa|up_9|NZ_CP023298.1_3431478_3433725_+	PRK11249, katE, hydroperoxidase II; Provisional	NA|342aa|up_8|NZ_CP023298.1_3434004_3435030_-	NA	NA|131aa|up_7|NZ_CP023298.1_3435183_3435576_-	PRK03624, PRK03624, putative acetyltransferase; Provisional	NA|999aa|up_6|NZ_CP023298.1_3435584_3438581_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|813aa|up_5|NZ_CP023298.1_3438880_3441319_+	sd00006, TPR, Tetratricopeptide repeat	NA|983aa|up_4|NZ_CP023298.1_3441320_3444269_+	pfam00931, NB-ARC, NB-ARC domain	NA|459aa|up_3|NZ_CP023298.1_3444265_3445642_+	pfam12770, CHAT, CHAT domain	NA|323aa|up_2|NZ_CP023298.1_3445610_3446579_+	NA	NA|342aa|up_1|NZ_CP023298.1_3446584_3447610_-	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed	NA|731aa|up_0|NZ_CP023298.1_3448178_3450371_+	PRK15061, PRK15061, catalase/peroxidase	NA|324aa|down_0|NZ_CP023298.1_3454253_3455225_+	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins	NA|246aa|down_1|NZ_CP023298.1_3455490_3456228_+	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071)	NA|211aa|down_2|NZ_CP023298.1_3456367_3457000_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|631aa|down_3|NZ_CP023298.1_3457072_3458965_+	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA	NA|512aa|down_4|NZ_CP023298.1_3459000_3460536_+	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain	NA|624aa|down_5|NZ_CP023298.1_3460535_3462407_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|381aa|down_6|NZ_CP023298.1_3462408_3463551_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|397aa|down_7|NZ_CP023298.1_3463544_3464735_-	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase	NA|547aa|down_8|NZ_CP023298.1_3464930_3466571_+	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|402aa|down_9|NZ_CP023298.1_3467562_3468768_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	10	4385947-4386061	9	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CGGGTTCGCGCCGCCGTCGGCCGGGCCCTCG	31	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|288aa|up_9|NZ_CP023298.1_4375893_4376757_+,NA|204aa|up_8|NZ_CP023298.1_4376778_4377390_-,NA|206aa|up_7|NZ_CP023298.1_4377609_4378227_+,NA|347aa|up_5|NZ_CP023298.1_4379020_4380061_-,NA|164aa|up_2|NZ_CP023298.1_4382919_4383411_+,NA|153aa|down_1|NZ_CP023298.1_4387429_4387888_+,NA|143aa|down_3|NZ_CP023298.1_4390537_4390966_+,NA|144aa|down_7|NZ_CP023298.1_4392778_4393210_-,NA|76aa|down_8|NZ_CP023298.1_4393227_4393455_-,NA|139aa|down_9|NZ_CP023298.1_4393463_4393880_-	NA|288aa|up_9|NZ_CP023298.1_4375893_4376757_+	NA	NA|204aa|up_8|NZ_CP023298.1_4376778_4377390_-	NA	NA|206aa|up_7|NZ_CP023298.1_4377609_4378227_+	NA	NA|224aa|up_6|NZ_CP023298.1_4378223_4378895_+	pfam13761, DUF4166, Domain of unknown function (DUF4166)	NA|347aa|up_5|NZ_CP023298.1_4379020_4380061_-	NA	NA|172aa|up_4|NZ_CP023298.1_4380240_4380756_-	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|319aa|up_3|NZ_CP023298.1_4380891_4381848_+	cd03138, GATase1_AraC_2, AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain	NA|164aa|up_2|NZ_CP023298.1_4382919_4383411_+	NA	NA|391aa|up_1|NZ_CP023298.1_4383523_4384696_-	PRK12678, PRK12678, transcription termination factor Rho; Provisional	NA|389aa|up_0|NZ_CP023298.1_4384747_4385914_-	pfam08007, Cupin_4, Cupin superfamily protein	NA|390aa|down_0|NZ_CP023298.1_4386194_4387364_+	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|153aa|down_1|NZ_CP023298.1_4387429_4387888_+	NA	NA|877aa|down_2|NZ_CP023298.1_4387898_4390529_+	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp	NA|143aa|down_3|NZ_CP023298.1_4390537_4390966_+	NA	NA|139aa|down_4|NZ_CP023298.1_4390962_4391379_+	pfam06271, RDD, RDD family	NA|350aa|down_5|NZ_CP023298.1_4391375_4392425_+	PRK13517, PRK13517, glutamate--cysteine ligase	NA|92aa|down_6|NZ_CP023298.1_4392498_4392774_-	pfam09851, SHOCT, Short C-terminal domain	NA|144aa|down_7|NZ_CP023298.1_4392778_4393210_-	NA	NA|76aa|down_8|NZ_CP023298.1_4393227_4393455_-	NA	NA|139aa|down_9|NZ_CP023298.1_4393463_4393880_-	NA
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	11	5587956-5588176	10	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGCGGCGGGACGATGCGCTGCCGGGGCG	29	1	1	5588129-5588147	NZ_CP023298.1_5835307-5835325	NA	4	4	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|81aa|up_0|NZ_CP023298.1_5586471_5586714_+,NA|102aa|down_0|NZ_CP023298.1_5590099_5590405_-,NA|54aa|down_1|NZ_CP023298.1_5590868_5591030_-	NA|416aa|up_9|NZ_CP023298.1_5574321_5575569_-	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism]	NA|512aa|up_8|NZ_CP023298.1_5575565_5577101_-	PRK13549, PRK13549, xylose transporter ATP-binding subunit; Provisional	NA|358aa|up_7|NZ_CP023298.1_5577171_5578245_-	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system	NA|496aa|up_6|NZ_CP023298.1_5578325_5579813_-	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|328aa|up_5|NZ_CP023298.1_5580148_5581132_-	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators	NA|474aa|up_4|NZ_CP023298.1_5581302_5582724_+	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252)	NA|141aa|up_3|NZ_CP023298.1_5582720_5583143_+	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme	NA|510aa|up_2|NZ_CP023298.1_5583037_5584567_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|384aa|up_1|NZ_CP023298.1_5585111_5586263_-	cd03814, GT4-like, glycosyltransferase family 4 proteins	NA|81aa|up_0|NZ_CP023298.1_5586471_5586714_+	NA	NA|102aa|down_0|NZ_CP023298.1_5590099_5590405_-	NA	NA|54aa|down_1|NZ_CP023298.1_5590868_5591030_-	NA	NA|517aa|down_2|NZ_CP023298.1_5592917_5594468_+	COG0457, NrfG, FOG: TPR repeat [General function prediction only]	NA|349aa|down_3|NZ_CP023298.1_5594451_5595498_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|273aa|down_4|NZ_CP023298.1_5595538_5596357_-	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism]	NA|395aa|down_5|NZ_CP023298.1_5596390_5597575_-	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB	NA|229aa|down_6|NZ_CP023298.1_5597571_5598258_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|451aa|down_7|NZ_CP023298.1_5598254_5599607_-	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit	NA|237aa|down_8|NZ_CP023298.1_5599676_5600387_-	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD	NA|255aa|down_9|NZ_CP023298.1_5600575_5601340_-	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	12	5885684-5885778	11	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGACCGGCGGAACCGTCGCCG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|185aa|down_0|NZ_CP023298.1_5885814_5886369_+,NA|225aa|down_7|NZ_CP023298.1_5891461_5892136_-	NA|448aa|up_9|NZ_CP023298.1_5874161_5875505_-	COG3866, PelB, Pectate lyase [Carbohydrate transport and metabolism]	NA|112aa|up_8|NZ_CP023298.1_5875590_5875926_-	cd06988, cupin_DddK, Dimethylsulfoniopropionate lyase DddK and related proteins, cupin domain	NA|366aa|up_7|NZ_CP023298.1_5875903_5877001_-	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]	NA|485aa|up_6|NZ_CP023298.1_5877097_5878552_-	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]	NA|470aa|up_5|NZ_CP023298.1_5878548_5879958_-	PRK02925, PRK02925, glucuronate isomerase; Reviewed	NA|442aa|up_4|NZ_CP023298.1_5879954_5881280_-	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]	NA|342aa|up_3|NZ_CP023298.1_5881457_5882483_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|426aa|up_2|NZ_CP023298.1_5882492_5883770_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|325aa|up_1|NZ_CP023298.1_5883775_5884750_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|278aa|up_0|NZ_CP023298.1_5884750_5885584_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|185aa|down_0|NZ_CP023298.1_5885814_5886369_+	NA	NA|156aa|down_1|NZ_CP023298.1_5886477_5886945_-	COG1522, Lrp, Transcriptional regulators [Transcription]	NA|373aa|down_2|NZ_CP023298.1_5887085_5888204_+	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains	NA|238aa|down_3|NZ_CP023298.1_5888400_5889114_-	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated	NA|61aa|down_4|NZ_CP023298.1_5889381_5889564_-	PRK14236, PRK14236, phosphate transporter ATP-binding protein; Provisional	NA|216aa|down_5|NZ_CP023298.1_5889576_5890224_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|418aa|down_6|NZ_CP023298.1_5890211_5891465_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|225aa|down_7|NZ_CP023298.1_5891461_5892136_-	NA	NA|362aa|down_8|NZ_CP023298.1_5892210_5893296_-	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|369aa|down_9|NZ_CP023298.1_5893483_5894590_+	cd06216, FNR_iron_sulfur_binding_2, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	13	6195284-6195397	12	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGGGCCCGCAGAGGAATCCGGACGCGCC	28	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|213aa|up_9|NZ_CP023298.1_6183057_6183696_+,NA|138aa|up_8|NZ_CP023298.1_6185002_6185416_+,NA|408aa|up_7|NZ_CP023298.1_6185606_6186830_-,NA|335aa|down_3|NZ_CP023298.1_6200292_6201297_-,NA|140aa|down_6|NZ_CP023298.1_6203300_6203720_-	NA|213aa|up_9|NZ_CP023298.1_6183057_6183696_+	NA	NA|138aa|up_8|NZ_CP023298.1_6185002_6185416_+	NA	NA|408aa|up_7|NZ_CP023298.1_6185606_6186830_-	NA	NA|367aa|up_6|NZ_CP023298.1_6186867_6187968_-	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn)	NA|220aa|up_5|NZ_CP023298.1_6187957_6188617_-	pfam02397, Bac_transf, Bacterial sugar transferase	NA|419aa|up_4|NZ_CP023298.1_6188629_6189886_-	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]	NA|651aa|up_3|NZ_CP023298.1_6189915_6191868_-	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]	NA|374aa|up_2|NZ_CP023298.1_6192235_6193357_+	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins	NA|188aa|up_1|NZ_CP023298.1_6193289_6193853_-	pfam04892, VanZ, VanZ like family	NA|202aa|up_0|NZ_CP023298.1_6194145_6194751_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|523aa|down_0|NZ_CP023298.1_6195514_6197083_-	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily	NA|204aa|down_1|NZ_CP023298.1_6197219_6197831_-	pfam02517, Abi, CAAX protease self-immunity	NA|639aa|down_2|NZ_CP023298.1_6198179_6200096_+	PRK13351, PRK13351, elongation factor G-like protein	NA|335aa|down_3|NZ_CP023298.1_6200292_6201297_-	NA	NA|404aa|down_4|NZ_CP023298.1_6201498_6202710_+	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|222aa|down_5|NZ_CP023298.1_6202628_6203294_+	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|140aa|down_6|NZ_CP023298.1_6203300_6203720_-	NA	NA|456aa|down_7|NZ_CP023298.1_6203786_6205154_-	TIGR03356, BGL, beta-galactosidase	NA|299aa|down_8|NZ_CP023298.1_6205150_6206047_-	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|305aa|down_9|NZ_CP023298.1_6206053_6206968_-	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	14	6284126-6284214	13	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CCCGCACCGCAACATCGGCCACGGCC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|141aa|up_4|NZ_CP023298.1_6280080_6280503_+,NA|572aa|down_9|NZ_CP023298.1_6300151_6301867_+	NA|528aa|up_9|NZ_CP023298.1_6272385_6273969_+	PRK12853, PRK12853, glucose-6-phosphate dehydrogenase	NA|529aa|up_8|NZ_CP023298.1_6273957_6275544_-	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|880aa|up_7|NZ_CP023298.1_6275547_6278187_-	PRK08257, PRK08257, acetyl-CoA acetyltransferase; Validated	NA|199aa|up_6|NZ_CP023298.1_6278283_6278880_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|384aa|up_5|NZ_CP023298.1_6278882_6280034_+	cd01160, LCAD, Long chain acyl-CoA dehydrogenase	NA|141aa|up_4|NZ_CP023298.1_6280080_6280503_+	NA	NA|125aa|up_3|NZ_CP023298.1_6280525_6280900_-	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown]	NA|151aa|up_2|NZ_CP023298.1_6281124_6281577_-	pfam03780, Asp23, Asp23 family, cell envelope-related function	NA|114aa|up_1|NZ_CP023298.1_6281745_6282087_+	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3	NA|665aa|up_0|NZ_CP023298.1_6282079_6284074_-	COG3276, SelB, Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]	NA|429aa|down_0|NZ_CP023298.1_6284365_6285652_-	PRK04311, PRK04311, selenocysteine synthase; Provisional	NA|258aa|down_1|NZ_CP023298.1_6285915_6286689_+	cd05483, retropepsin_like_bacteria, Bacterial aspartate proteases, retropepsin-like protease family	NA|403aa|down_2|NZ_CP023298.1_6287000_6288209_-	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism]	NA|779aa|down_3|NZ_CP023298.1_6288367_6290704_-	pfam13229, Beta_helix, Right handed beta helix region	NA|331aa|down_4|NZ_CP023298.1_6291160_6292153_+	TIGR00476, selenide_water_dikinase, selenium donor protein	NA|676aa|down_5|NZ_CP023298.1_6292190_6294218_-	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|304aa|down_6|NZ_CP023298.1_6294448_6295360_-	pfam03916, NrfD, Polysulphide reductase, NrfD	NA|306aa|down_7|NZ_CP023298.1_6295380_6296298_-	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins	NA|1067aa|down_8|NZ_CP023298.1_6296299_6299500_-	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit	NA|572aa|down_9|NZ_CP023298.1_6300151_6301867_+	NA
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	15	7161443-7161533	14	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GGCGGACCGCGAGCGGCCCGCCCTCCGAA	29	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|84aa|down_1|NZ_CP023298.1_7162659_7162911_-	NA|413aa|up_9|NZ_CP023298.1_7148340_7149579_-	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase	NA|306aa|up_8|NZ_CP023298.1_7149581_7150499_+	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase	NA|543aa|up_7|NZ_CP023298.1_7150522_7152151_-	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin	NA|446aa|up_6|NZ_CP023298.1_7152225_7153563_+	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|419aa|up_5|NZ_CP023298.1_7153559_7154816_+	PRK09237, PRK09237, amidohydrolase/deacetylase family metallohydrolase	NA|127aa|up_4|NZ_CP023298.1_7154815_7155196_+	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis]	NA|101aa|up_3|NZ_CP023298.1_7158035_7158338_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|136aa|up_2|NZ_CP023298.1_7158334_7158742_+	pfam00699, Urease_beta, Urease beta subunit	NA|523aa|up_1|NZ_CP023298.1_7158738_7160307_+	PRK13206, ureC, urease subunit alpha; Reviewed	NA|348aa|up_0|NZ_CP023298.1_7160316_7161360_-	cd08260, Zn_ADH6, Alcohol dehydrogenases of the MDR family	NA|301aa|down_0|NZ_CP023298.1_7161541_7162444_-	COG1191, FliA, DNA-directed RNA polymerase specialized sigma subunit [Transcription]	NA|84aa|down_1|NZ_CP023298.1_7162659_7162911_-	NA	NA|616aa|down_2|NZ_CP023298.1_7163243_7165091_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|905aa|down_3|NZ_CP023298.1_7165464_7168179_-	PRK14016, PRK14016, cyanophycin synthetase; Provisional	NA|296aa|down_4|NZ_CP023298.1_7168069_7168957_-	TIGR02069, cyanophycinase, cyanophycinase	NA|163aa|down_5|NZ_CP023298.1_7169111_7169600_-	COG1733, COG1733, Predicted transcriptional regulators [Transcription]	NA|174aa|down_6|NZ_CP023298.1_7169656_7170178_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|437aa|down_7|NZ_CP023298.1_7170207_7171518_-	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed	NA|233aa|down_8|NZ_CP023298.1_7171538_7172237_-	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|290aa|down_9|NZ_CP023298.1_7172385_7173255_+	cd00317, cyclophilin, cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	16	7827086-7827166	15	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTGCTCTGACCGCGACCACCCACGGA	26	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|570aa|down_5|NZ_CP023298.1_7834063_7835773_+	NA|266aa|up_9|NZ_CP023298.1_7818485_7819283_-	pfam00303, Thymidylat_synt, Thymidylate synthase	NA|202aa|up_8|NZ_CP023298.1_7819295_7819901_-	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional	NA|85aa|up_7|NZ_CP023298.1_7819969_7820224_-	cd07184, E_set_Isoamylase_like_N, N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins	NA|152aa|up_6|NZ_CP023298.1_7820306_7820762_+	COG2153, ElaA, Predicted acyltransferase [General function prediction only]	NA|234aa|up_5|NZ_CP023298.1_7820748_7821450_-	pfam06778, Chlor_dismutase, Chlorite dismutase	NA|465aa|up_4|NZ_CP023298.1_7821446_7822841_-	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed	NA|373aa|up_3|NZ_CP023298.1_7822906_7824025_-	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated	NA|191aa|up_2|NZ_CP023298.1_7824023_7824596_+	pfam11452, DUF3000, Protein of unknown function (DUF3000)	NA|337aa|up_1|NZ_CP023298.1_7824605_7825616_-	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|434aa|up_0|NZ_CP023298.1_7825761_7827063_+	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis]	NA|399aa|down_0|NZ_CP023298.1_7827449_7828646_+	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine	NA|688aa|down_1|NZ_CP023298.1_7828642_7830706_+	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ	NA|303aa|down_2|NZ_CP023298.1_7830805_7831714_+	pfam09770, PAT1, Topoisomerase II-associated protein PAT1	NA|411aa|down_3|NZ_CP023298.1_7831710_7832943_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|221aa|down_4|NZ_CP023298.1_7832939_7833602_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|570aa|down_5|NZ_CP023298.1_7834063_7835773_+	NA	NA|450aa|down_6|NZ_CP023298.1_7836815_7838165_-	pfam13360, PQQ_2, PQQ-like domain	NA|436aa|down_7|NZ_CP023298.1_7838232_7839540_-	pfam13360, PQQ_2, PQQ-like domain	NA|641aa|down_8|NZ_CP023298.1_7839588_7841511_-	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional	NA|468aa|down_9|NZ_CP023298.1_7841660_7843064_+	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	17	7857635-7857740	16	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GATGTCGTGCGCTCCGGCCGATAA	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|255aa|up_5|NZ_CP023298.1_7852325_7853090_-,NA|81aa|up_0|NZ_CP023298.1_7857282_7857525_+,NA|91aa|down_9|NZ_CP023298.1_7866620_7866893_-	NA|126aa|up_9|NZ_CP023298.1_7850255_7850633_-	cd04488, RecG_wedge_OBF, RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG	NA|216aa|up_8|NZ_CP023298.1_7850658_7851306_-	pfam12502, DUF3710, Protein of unknown function (DUF3710)	NA|159aa|up_7|NZ_CP023298.1_7851292_7851769_-	PRK00601, dut, dUTP diphosphatase	NA|171aa|up_6|NZ_CP023298.1_7851862_7852375_+	pfam11292, DUF3093, Protein of unknown function (DUF3093)	NA|255aa|up_5|NZ_CP023298.1_7852325_7853090_-	NA	NA|99aa|up_4|NZ_CP023298.1_7853215_7853512_-	pfam13834, DUF4193, Domain of unknown function (DUF4193)	NA|183aa|up_3|NZ_CP023298.1_7853857_7854406_+	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator	NA|271aa|up_2|NZ_CP023298.1_7854414_7855227_-	cd01639, IMPase, IMPase, inositol monophosphatase and related domains	NA|516aa|up_1|NZ_CP023298.1_7855490_7857038_+	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional	NA|81aa|up_0|NZ_CP023298.1_7857282_7857525_+	NA	NA|526aa|down_0|NZ_CP023298.1_7858357_7859935_-	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain	NA|577aa|down_1|NZ_CP023298.1_7859986_7861717_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|205aa|down_2|NZ_CP023298.1_7861810_7862425_-	COG2860, COG2860, Predicted membrane protein [Function unknown]	NA|73aa|down_3|NZ_CP023298.1_7862432_7862651_-	pfam11238, DUF3039, Protein of unknown function (DUF3039)	NA|317aa|down_4|NZ_CP023298.1_7862774_7863725_+	pfam04227, Indigoidine_A, Indigoidine synthase A like protein	NA|296aa|down_5|NZ_CP023298.1_7863910_7864798_+	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)	NA|124aa|down_6|NZ_CP023298.1_7865025_7865397_-	pfam11298, DUF3099, Protein of unknown function (DUF3099)	NA|195aa|down_7|NZ_CP023298.1_7865498_7866083_-	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein	NA|167aa|down_8|NZ_CP023298.1_7866123_7866624_-	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms]	NA|91aa|down_9|NZ_CP023298.1_7866620_7866893_-	NA
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	18	7916744-7916846	17	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	ACCGGCGGCTTCGGATGCCGGCGC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|241aa|up_8|NZ_CP023298.1_7907679_7908402_-,NA|151aa|up_5|NZ_CP023298.1_7910621_7911074_-,NA	NA|317aa|up_9|NZ_CP023298.1_7906716_7907667_+	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|241aa|up_8|NZ_CP023298.1_7907679_7908402_-	NA	NA|166aa|up_7|NZ_CP023298.1_7908404_7908902_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|501aa|up_6|NZ_CP023298.1_7909095_7910598_-	PRK14326, PRK14326, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional	NA|151aa|up_5|NZ_CP023298.1_7910621_7911074_-	NA	NA|248aa|up_4|NZ_CP023298.1_7911199_7911943_+	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]	NA|294aa|up_3|NZ_CP023298.1_7912005_7912887_+	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold	NA|237aa|up_2|NZ_CP023298.1_7912928_7913639_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|323aa|up_1|NZ_CP023298.1_7913712_7914681_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|575aa|up_0|NZ_CP023298.1_7914759_7916484_-	PRK12704, PRK12704, phosphodiesterase; Provisional	NA|213aa|down_0|NZ_CP023298.1_7918404_7919043_-	PRK00117, recX, recombination regulator RecX; Reviewed	NA|349aa|down_1|NZ_CP023298.1_7919624_7920671_-	PRK09354, recA, recombinase A; Provisional	NA|67aa|down_2|NZ_CP023298.1_7920848_7921049_-	pfam11248, DUF3046, Protein of unknown function (DUF3046)	NA|222aa|down_3|NZ_CP023298.1_7921527_7922193_-	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|449aa|down_4|NZ_CP023298.1_7922658_7924005_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|414aa|down_5|NZ_CP023298.1_7924068_7925310_+	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase	NA|218aa|down_6|NZ_CP023298.1_7925332_7925986_+	PRK10958, PRK10958, leucine export protein LeuE; Provisional	NA|764aa|down_7|NZ_CP023298.1_7926171_7928463_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|1656aa|down_8|NZ_CP023298.1_7928598_7933566_+	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional	NA|309aa|down_9|NZ_CP023298.1_7933761_7934688_-	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	19	7933392-7933633	1	PILER-CR	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCGGCGCCGCTGCGGGAGGCGCTGACCGCCGCCGGGTTCCGGGCTACGCCGCG	53	1	1	7933583-7933618	NZ_CP023298.1_7933634-7933669	NA	2	2	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA	NA|323aa|up_9|NZ_CP023298.1_7913712_7914681_+	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]	NA|575aa|up_8|NZ_CP023298.1_7914759_7916484_-	PRK12704, PRK12704, phosphodiesterase; Provisional	NA|213aa|up_7|NZ_CP023298.1_7918404_7919043_-	PRK00117, recX, recombination regulator RecX; Reviewed	NA|349aa|up_6|NZ_CP023298.1_7919624_7920671_-	PRK09354, recA, recombinase A; Provisional	NA|67aa|up_5|NZ_CP023298.1_7920848_7921049_-	pfam11248, DUF3046, Protein of unknown function (DUF3046)	NA|222aa|up_4|NZ_CP023298.1_7921527_7922193_-	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain	NA|449aa|up_3|NZ_CP023298.1_7922658_7924005_-	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional	NA|414aa|up_2|NZ_CP023298.1_7924068_7925310_+	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase	NA|218aa|up_1|NZ_CP023298.1_7925332_7925986_+	PRK10958, PRK10958, leucine export protein LeuE; Provisional	NA|764aa|up_0|NZ_CP023298.1_7926171_7928463_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|309aa|down_0|NZ_CP023298.1_7933761_7934688_-	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family	NA|264aa|down_1|NZ_CP023298.1_7934760_7935552_+	pfam01887, SAM_adeno_trans, S-adenosyl-l-methionine hydroxide adenosyltransferase	NA|288aa|down_2|NZ_CP023298.1_7937515_7938379_-	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]	NA|133aa|down_3|NZ_CP023298.1_7938866_7939265_-	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|162aa|down_4|NZ_CP023298.1_7939426_7939912_-	pfam02464, CinA, Competence-damaged protein	NA|197aa|down_5|NZ_CP023298.1_7939975_7940566_-	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA|487aa|down_6|NZ_CP023298.1_7940562_7942023_-	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO	NA|220aa|down_7|NZ_CP023298.1_7942111_7942771_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|158aa|down_8|NZ_CP023298.1_7942803_7943277_+	pfam11695, DUF3291, Domain of unknown function (DUF3291)	NA|830aa|down_9|NZ_CP023298.1_7943398_7945888_-	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	20	8356581-8356645	18	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCACAACGCCGCGCGACGAAGCAC	24	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|126aa|up_2|NZ_CP023298.1_8354009_8354387_-,NA	NA|372aa|up_9|NZ_CP023298.1_8347153_8348269_+	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed	NA|314aa|up_8|NZ_CP023298.1_8349302_8350244_-	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family	NA|411aa|up_7|NZ_CP023298.1_8350588_8351821_-	COG0281, SfcA, Malic enzyme [Energy production and conversion]	NA|87aa|up_6|NZ_CP023298.1_8351959_8352220_-	cd06530, S26_SPase_I, The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3	NA|135aa|up_5|NZ_CP023298.1_8352353_8352758_+	pfam09055, Sod_Ni, Nickel-containing superoxide dismutase	NA|136aa|up_4|NZ_CP023298.1_8352853_8353261_+	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|235aa|up_3|NZ_CP023298.1_8353266_8353971_-	COG2186, FadR, Transcriptional regulators [Transcription]	NA|126aa|up_2|NZ_CP023298.1_8354009_8354387_-	NA	NA|317aa|up_1|NZ_CP023298.1_8354456_8355407_+	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]	NA|85aa|up_0|NZ_CP023298.1_8355818_8356073_+	pfam02467, Whib, Transcription factor WhiB	NA|303aa|down_0|NZ_CP023298.1_8356711_8357620_-	cd03416, CbiX_SirB_N, Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain	NA|255aa|down_1|NZ_CP023298.1_8357601_8358366_-	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase	NA|564aa|down_2|NZ_CP023298.1_8358517_8360209_-	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]	NA|513aa|down_3|NZ_CP023298.1_8360754_8362293_-	pfam12282, H_kinase_N, Signal transduction histidine kinase	NA|339aa|down_4|NZ_CP023298.1_8362322_8363339_-	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]	NA|524aa|down_5|NZ_CP023298.1_8363470_8365042_+	sd00006, TPR, Tetratricopeptide repeat	NA|72aa|down_6|NZ_CP023298.1_8365043_8365259_-	PRK14040, PRK14040, oxaloacetate decarboxylase subunit alpha	NA|95aa|down_7|NZ_CP023298.1_8365654_8365939_-	TIGR03988, antisig_RsrA, mycothiol system anti-sigma-R factor	NA|200aa|down_8|NZ_CP023298.1_8365943_8366543_-	TIGR02947, putative_RNA_polymerase_sigma_factor, RNA polymerase sigma-70 factor, TIGR02947 family	NA|205aa|down_9|NZ_CP023298.1_8366796_8367411_-	COG3571, COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	21	8786368-8786548	19	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GCCGCCTCACCACCGCACACCGC	23	1	1	8786457-8786473	NZ_CP023298.1_2972395-2972379	NA	3	3	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|337aa|up_8|NZ_CP023298.1_8776984_8777995_+,NA|148aa|down_4|NZ_CP023298.1_8792271_8792715_+	NA|239aa|up_9|NZ_CP023298.1_8776000_8776717_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|337aa|up_8|NZ_CP023298.1_8776984_8777995_+	NA	NA|276aa|up_7|NZ_CP023298.1_8778029_8778857_+	pfam11209, DUF2993, Protein of unknown function (DUF2993)	NA|283aa|up_6|NZ_CP023298.1_8779180_8780029_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|112aa|up_5|NZ_CP023298.1_8780034_8780370_+	pfam07210, DUF1416, Protein of unknown function (DUF1416)	NA|216aa|up_4|NZ_CP023298.1_8780674_8781322_-	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown]	NA|374aa|up_3|NZ_CP023298.1_8781367_8782489_+	COG4129, COG4129, Predicted membrane protein [Function unknown]	NA|550aa|up_2|NZ_CP023298.1_8782840_8784490_+	pfam13367, PrsW-protease, Protease prsW family	NA|114aa|up_1|NZ_CP023298.1_8784480_8784822_-	smart00883, Cpn10, Chaperonin 10 Kd subunit	NA|448aa|up_0|NZ_CP023298.1_8784881_8786225_+	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only]	NA|96aa|down_0|NZ_CP023298.1_8786838_8787126_-	pfam13223, DUF4031, Protein of unknown function (DUF4031)	NA|157aa|down_1|NZ_CP023298.1_8789179_8789650_-	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of  thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides	NA|541aa|down_2|NZ_CP023298.1_8789756_8791379_-	PRK00013, groEL, chaperonin GroEL; Reviewed	NA|169aa|down_3|NZ_CP023298.1_8791765_8792272_+	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|148aa|down_4|NZ_CP023298.1_8792271_8792715_+	NA	NA|428aa|down_5|NZ_CP023298.1_8792931_8794215_-	PRK07591, PRK07591, threonine synthase; Validated	NA|292aa|down_6|NZ_CP023298.1_8794567_8795443_-	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein	NA|902aa|down_7|NZ_CP023298.1_8795439_8798145_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|720aa|down_8|NZ_CP023298.1_8798275_8800435_+	TIGR01243, Cell_division_cycle_protein_48_homolog_MJ1156, AAA family ATPase, CDC48 subfamily	NA|95aa|down_9|NZ_CP023298.1_8800437_8800722_-	pfam11662, DUF3263, Protein of unknown function (DUF3263)
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	22	9194187-9194258	20	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	GTTGTTGCCACCACCGTTGTTGTT	24	1	1	9194211-9194234	NZ_CP023298.1_9194244-9194267	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA,NA|253aa|down_8|NZ_CP023298.1_9205740_9206499_-	NA|102aa|up_9|NZ_CP023298.1_9176969_9177275_+	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family	NA|478aa|up_8|NZ_CP023298.1_9177572_9179006_-	TIGR00665, DnaB, replicative DNA helicase	NA|1554aa|up_7|NZ_CP023298.1_9179415_9184077_+	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|150aa|up_6|NZ_CP023298.1_9184892_9185342_-	PRK00137, rplI, 50S ribosomal protein L9; Reviewed	NA|80aa|up_5|NZ_CP023298.1_9185356_9185596_-	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed	NA|191aa|up_4|NZ_CP023298.1_9185664_9186237_-	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional	NA|97aa|up_3|NZ_CP023298.1_9186302_9186593_-	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed	NA|322aa|up_2|NZ_CP023298.1_9186889_9187855_-	PRK12373, PRK12373, NADH-quinone oxidoreductase subunit E	NA|258aa|up_1|NZ_CP023298.1_9187985_9188759_+	PRK01060, PRK01060, endonuclease IV; Provisional	NA|506aa|up_0|NZ_CP023298.1_9192457_9193975_-	COG5650, COG5650, Predicted integral membrane protein [Function unknown]	NA|145aa|down_0|NZ_CP023298.1_9196989_9197424_-	pfam17249, DUF5318, Family of unknown function (DUF5318)	NA|218aa|down_1|NZ_CP023298.1_9197585_9198239_+	COG1695, COG1695, Predicted transcriptional regulators [Transcription]	NA|360aa|down_2|NZ_CP023298.1_9198262_9199342_+	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type	NA|381aa|down_3|NZ_CP023298.1_9199487_9200630_+	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap	NA|734aa|down_4|NZ_CP023298.1_9200709_9202911_+	cd06225, HAMP, Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain	NA|425aa|down_5|NZ_CP023298.1_9202913_9204188_+	TIGR04012, poly_gGlu_PgsB, poly-gamma-glutamate synthase PgsB/CapB	NA|162aa|down_6|NZ_CP023298.1_9204184_9204670_+	pfam14102, Caps_synth_CapC, Capsule biosynthesis CapC	NA|348aa|down_7|NZ_CP023298.1_9204680_9205724_+	pfam00877, NLPC_P60, NlpC/P60 family	NA|253aa|down_8|NZ_CP023298.1_9205740_9206499_-	NA	NA|152aa|down_9|NZ_CP023298.1_9206712_9207168_-	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]
GCF_002717025.1_ASM271702v1	NZ_CP023298	Actinoplanes sp. SE50 chromosome, complete genome	23	9229284-9229368	21	CRISPRCasFinder	no		csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	Orphan	CGATCCCGCGTCCGACCCGACCC	23	0	0	NA	NA	NA	1	1	Orphan	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	NA|406aa|up_6|NZ_CP023298.1_9220194_9221412_+,NA|217aa|up_2|NZ_CP023298.1_9224084_9224735_-,NA	NA|559aa|up_9|NZ_CP023298.1_9215861_9217538_+	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins	NA|518aa|up_8|NZ_CP023298.1_9217759_9219313_+	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN	NA|236aa|up_7|NZ_CP023298.1_9219490_9220198_+	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed	NA|406aa|up_6|NZ_CP023298.1_9220194_9221412_+	NA	NA|320aa|up_5|NZ_CP023298.1_9221516_9222476_+	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase	NA|106aa|up_4|NZ_CP023298.1_9222492_9222810_+	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin	NA|384aa|up_3|NZ_CP023298.1_9222932_9224084_+	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3	NA|217aa|up_2|NZ_CP023298.1_9224084_9224735_-	NA	NA|437aa|up_1|NZ_CP023298.1_9224929_9226240_+	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|321aa|up_0|NZ_CP023298.1_9226236_9227199_+	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed	NA|211aa|down_0|NZ_CP023298.1_9231436_9232069_-	TIGR00997, Probable_intracellular_septation_protein_A, intracellular septation protein A	NA|354aa|down_1|NZ_CP023298.1_9232355_9233417_-	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein	NA|278aa|down_2|NZ_CP023298.1_9233413_9234247_-	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]	NA|296aa|down_3|NZ_CP023298.1_9234850_9235738_-	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA|196aa|down_4|NZ_CP023298.1_9235739_9236327_-	COG1847, Jag, Predicted RNA-binding protein [General function prediction only]	NA|341aa|down_5|NZ_CP023298.1_9236471_9237494_-	PRK01315, PRK01315, putative inner membrane protein translocase component YidC; Provisional	NA|86aa|down_6|NZ_CP023298.1_9237495_9237753_-	pfam01809, Haemolytic, Haemolytic domain	NA|119aa|down_7|NZ_CP023298.1_9237749_9238106_-	PRK03459, rnpA, ribonuclease P; Reviewed	NA|46aa|down_8|NZ_CP023298.1_9238142_9238280_-	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed	NA|NA	NA
