assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	1	338108-338330	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCG--CCGGTGCCGCCGGCGCC----------GAACAGCCCGCC	55	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_0|NZ_CP025598.1_333164_333347_-,NA	NA|398aa|up_9|NZ_CP025598.1_323342_324536_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP025598.1_324571_326254_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP025598.1_326270_328466_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP025598.1_328579_329713_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP025598.1_329709_330330_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP025598.1_330426_331008_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP025598.1_330937_331663_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP025598.1_331752_332673_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP025598.1_332712_333141_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP025598.1_333164_333347_-	NA	NA|537aa|down_0|NZ_CP025598.1_339367_340978_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP025598.1_341001_341910_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP025598.1_342133_344029_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP025598.1_344025_345642_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP025598.1_345638_349631_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP025598.1_349627_349936_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP025598.1_349938_351480_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP025598.1_351528_351822_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP025598.1_351851_352142_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP025598.1_352152_353040_+	pfam14011, ESX-1_EspG, EspG family
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	2	366467-367165	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366755-366796|366830-366862	NZ_CP025598.1_374786-374827|NZ_CP025598.1_373601-373633	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP025598.1_363479_363782_+,NA|161aa|down_1|NZ_CP025598.1_376575_377058_-,NA|410aa|down_5|NZ_CP025598.1_379174_380404_+	NA|262aa|up_9|NZ_CP025598.1_358174_358960_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP025598.1_358948_359752_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP025598.1_359761_361159_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP025598.1_361337_363113_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP025598.1_363255_363483_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP025598.1_363479_363782_+	NA	NA|74aa|up_3|NZ_CP025598.1_363829_364051_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP025598.1_364047_364473_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP025598.1_364608_365241_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP025598.1_365237_366146_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP025598.1_375916_376588_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP025598.1_376575_377058_-	NA	NA|239aa|down_2|NZ_CP025598.1_377115_377832_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP025598.1_377933_378590_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP025598.1_378659_379151_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP025598.1_379174_380404_+	NA	NA|621aa|down_6|NZ_CP025598.1_380558_382421_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP025598.1_382492_382879_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP025598.1_382881_383544_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP025598.1_383604_384489_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	3	692005-692081	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP025598.1_677689_677905_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP025598.1_677901_678309_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP025598.1_678368_679055_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP025598.1_679208_681842_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP025598.1_681864_684252_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP025598.1_684389_685112_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP025598.1_685108_685906_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP025598.1_685907_686795_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP025598.1_686800_688015_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP025598.1_689038_690484_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP025598.1_693216_694767_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP025598.1_694818_695211_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP025598.1_695207_695465_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP025598.1_695647_696883_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP025598.1_697133_697547_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP025598.1_697543_697780_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP025598.1_697883_698390_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP025598.1_698503_698974_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP025598.1_699017_699779_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP025598.1_699835_700147_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	4	926599-927546	1	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927382-927417|927382-927417|927382-927417	NZ_CP025598.1_675108-675073|NZ_CP025598.1_1213730-1213765|NZ_CP025598.1_2423782-2423747	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_1|NZ_CP025598.1_931546_932098_-,NA|81aa|down_7|NZ_CP025598.1_937561_937804_+	NA|685aa|up_9|NZ_CP025598.1_914235_916290_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP025598.1_916455_917625_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP025598.1_917712_918729_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP025598.1_918890_919532_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP025598.1_919612_920668_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP025598.1_920719_921112_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP025598.1_921169_921592_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP025598.1_921553_921844_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP025598.1_921948_922854_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP025598.1_922872_923688_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|215aa|down_0|NZ_CP025598.1_930921_931566_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_1|NZ_CP025598.1_931546_932098_-	NA	NA|218aa|down_2|NZ_CP025598.1_932247_932901_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_3|NZ_CP025598.1_932971_934000_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_4|NZ_CP025598.1_934688_935459_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_5|NZ_CP025598.1_935545_936358_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_6|NZ_CP025598.1_936425_937286_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_7|NZ_CP025598.1_937561_937804_+	NA	NA|431aa|down_8|NZ_CP025598.1_938080_939373_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|335aa|down_9|NZ_CP025598.1_939356_940361_+	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	5	964549-964825	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ACCTGGCGCCACCCGCGCCCGCCGAACTGGCGCCACCCGCGCCCGCCGACCTGGCACCACCCGC	64	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|67aa|up_3|NZ_CP025598.1_962648_962849_+,NA	NA|158aa|up_9|NZ_CP025598.1_953225_953699_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_8|NZ_CP025598.1_953695_954889_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|404aa|up_7|NZ_CP025598.1_955045_956257_+	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|721aa|up_6|NZ_CP025598.1_956261_958424_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NZ_CP025598.1_958491_960120_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NZ_CP025598.1_960310_962581_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NZ_CP025598.1_962648_962849_+	NA	NA|168aa|up_2|NZ_CP025598.1_962858_963362_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NZ_CP025598.1_963358_963841_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NZ_CP025598.1_963837_964263_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NZ_CP025598.1_965951_966230_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|361aa|down_1|NZ_CP025598.1_966233_967316_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NZ_CP025598.1_967312_967702_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NZ_CP025598.1_967866_968274_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|610aa|down_4|NZ_CP025598.1_968392_970222_-	pfam00934, PE, PE family	NA|651aa|down_5|NZ_CP025598.1_970482_972435_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_6|NZ_CP025598.1_972523_973684_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_7|NZ_CP025598.1_973783_974272_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_8|NZ_CP025598.1_974268_975915_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|263aa|down_9|NZ_CP025598.1_976052_976841_+	pfam11228, DUF3027, Protein of unknown function (DUF3027)
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	6	1191297-1191405	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP025598.1_1180664_1182296_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP025598.1_1182371_1183436_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP025598.1_1183488_1183962_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP025598.1_1183995_1184859_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP025598.1_1184863_1185721_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP025598.1_1185721_1186804_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP025598.1_1186884_1187304_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP025598.1_1187415_1187982_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP025598.1_1187978_1188374_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP025598.1_1188401_1190405_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP025598.1_1192490_1194254_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP025598.1_1194250_1195024_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP025598.1_1195035_1196073_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP025598.1_1196259_1197096_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP025598.1_1197211_1198063_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP025598.1_1198136_1199354_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP025598.1_1199406_1200351_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP025598.1_1200573_1201641_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP025598.1_1201697_1203092_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP025598.1_1203293_1204016_+	pfam06271, RDD, RDD family
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	7	1211931-1212787	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	73	1212314-1212335|1212359-1212374|1212497-1212518|1212497-1212518|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632|1212614-1212632	NZ_CP025598.1_2960555-2960534|NZ_CP025598.1_2088584-2088569|NZ_CP025598.1_837411-837432|NZ_CP025598.1_1217625-1217646|NZ_CP025598.1_1572809-1572791|NZ_CP025598.1_674772-674754|NZ_CP025598.1_1213457-1213475|NZ_CP025598.1_1217598-1217616|NZ_CP025598.1_1217670-1217688|NZ_CP025598.1_1630681-1630663|NZ_CP025598.1_1633507-1633489|NZ_CP025598.1_1990789-1990771|NZ_CP025598.1_2061512-2061494|NZ_CP025598.1_2061959-2061941|NZ_CP025598.1_2062058-2062040|NZ_CP025598.1_2802104-2802086|NZ_CP025598.1_2805632-2805614|NZ_CP025598.1_150189-150207|NZ_CP025598.1_333787-333769|NZ_CP025598.1_335206-335188|NZ_CP025598.1_335659-335641|NZ_CP025598.1_335710-335692|NZ_CP025598.1_335719-335701|NZ_CP025598.1_338007-337989|NZ_CP025598.1_338403-338385|NZ_CP025598.1_338432-338450|NZ_CP025598.1_338526-338508|NZ_CP025598.1_363057-363039|NZ_CP025598.1_443431-443413|NZ_CP025598.1_546773-546755|NZ_CP025598.1_623963-623981|NZ_CP025598.1_624185-624203|NZ_CP025598.1_673938-673920|NZ_CP025598.1_840194-840212|NZ_CP025598.1_1090957-1090975|NZ_CP025598.1_1091605-1091623|NZ_CP025598.1_1212986-1213004|NZ_CP025598.1_1213376-1213394|NZ_CP025598.1_1218018-1218036|NZ_CP025598.1_1489192-1489174|NZ_CP025598.1_1618645-1618627|NZ_CP025598.1_1619098-1619080|NZ_CP025598.1_1636020-1636002|NZ_CP025598.1_1636029-1636011|NZ_CP025598.1_1864309-1864291|NZ_CP025598.1_1864837-1864819|NZ_CP025598.1_1990068-1990050|NZ_CP025598.1_2001425-2001443|NZ_CP025598.1_2088782-2088764|NZ_CP025598.1_2303529-2303511|NZ_CP025598.1_2356982-2356964|NZ_CP025598.1_2419608-2419626|NZ_CP025598.1_2423695-2423677|NZ_CP025598.1_2569189-2569171|NZ_CP025598.1_2693473-2693491|NZ_CP025598.1_2795418-2795400|NZ_CP025598.1_2796000-2795982|NZ_CP025598.1_3054599-3054617|NZ_CP025598.1_3054698-3054716|NZ_CP025598.1_3705534-3705552|NZ_CP025598.1_3737511-3737493|NZ_CP025598.1_3738135-3738117|NZ_CP025598.1_3738378-3738360|NZ_CP025598.1_3738511-3738493|NZ_CP025598.1_3802371-3802389|NZ_CP025598.1_3802554-3802572|NZ_CP025598.1_3802722-3802740|NZ_CP025598.1_3930531-3930549|NZ_CP025598.1_3932261-3932279|NZ_CP025598.1_3940750-3940768|NZ_CP025598.1_3948744-3948762|NZ_CP025598.1_4031724-4031706|NZ_CP025598.1_4094249-4094267	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP025598.1_1207363_1207630_+,NA|61aa|down_3|NZ_CP025598.1_1215205_1215388_+,NA|35aa|down_4|NZ_CP025598.1_1215497_1215602_+	NA|465aa|up_9|NZ_CP025598.1_1201697_1203092_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP025598.1_1203293_1204016_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP025598.1_1204047_1205214_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP025598.1_1205284_1205779_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP025598.1_1205964_1206399_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP025598.1_1206500_1207367_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP025598.1_1207363_1207630_+	NA	NA|674aa|up_2|NZ_CP025598.1_1207616_1209638_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP025598.1_1209736_1210465_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP025598.1_1210575_1211364_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP025598.1_1214020_1214341_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP025598.1_1214493_1214928_+	pfam00934, PE, PE family	NA|56aa|down_2|NZ_CP025598.1_1215026_1215194_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP025598.1_1215205_1215388_+	NA	NA|35aa|down_4|NZ_CP025598.1_1215497_1215602_+	NA	NA|152aa|down_5|NZ_CP025598.1_1215579_1216035_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|854aa|down_6|NZ_CP025598.1_1216449_1219011_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP025598.1_1219228_1220167_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP025598.1_1220554_1221835_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP025598.1_1221939_1222767_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	8	2088254-2088508	2	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088335-2088352|2088335-2088352|2088425-2088442	NZ_CP025598.1_401082-401065|NZ_CP025598.1_607418-607401|NZ_CP025598.1_3450222-3450205	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP025598.1_2087613_2087877_-,NA	NA|165aa|up_9|NZ_CP025598.1_2073907_2074402_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP025598.1_2074805_2075483_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP025598.1_2075841_2078667_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP025598.1_2078893_2079754_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP025598.1_2079794_2080661_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP025598.1_2080665_2082552_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP025598.1_2082567_2084601_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP025598.1_2084720_2086946_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP025598.1_2087221_2087617_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP025598.1_2087613_2087877_-	NA	NA|346aa|down_0|NZ_CP025598.1_2089645_2090683_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP025598.1_2090682_2092050_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP025598.1_2092223_2093660_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP025598.1_2093695_2095147_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP025598.1_2095176_2096127_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP025598.1_2096141_2096558_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP025598.1_2096835_2097258_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP025598.1_2097306_2097609_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP025598.1_2097605_2097920_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP025598.1_2097919_2099653_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	9	2163361-2163465	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CAACCCAAACGGATTAATCGCGAAACCAGGGATCGT	36	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_2|NZ_CP025598.1_2159905_2160313_-,NA|127aa|down_6|NZ_CP025598.1_2176564_2176945_-	NA|216aa|up_9|NZ_CP025598.1_2153219_2153867_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP025598.1_2153873_2156096_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP025598.1_2156133_2156577_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP025598.1_2156690_2157284_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP025598.1_2157366_2157972_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP025598.1_2158071_2159076_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP025598.1_2159175_2159928_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP025598.1_2159905_2160313_-	NA	NA|368aa|up_1|NZ_CP025598.1_2160447_2161551_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_0|NZ_CP025598.1_2161550_2162747_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|988aa|down_0|NZ_CP025598.1_2167663_2170627_-	pfam00823, PPE, PPE family	NA|155aa|down_1|NZ_CP025598.1_2171075_2171540_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_2|NZ_CP025598.1_2171637_2172501_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_3|NZ_CP025598.1_2172538_2173810_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_4|NZ_CP025598.1_2174081_2175197_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_5|NZ_CP025598.1_2175187_2176528_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_6|NZ_CP025598.1_2176564_2176945_-	NA	NA|621aa|down_7|NZ_CP025598.1_2177101_2178964_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_8|NZ_CP025598.1_2178971_2179451_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_9|NZ_CP025598.1_2179687_2180461_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	10	2168829-2169048	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP025598.1_2159905_2160313_-,NA|127aa|down_5|NZ_CP025598.1_2176564_2176945_-	NA|741aa|up_9|NZ_CP025598.1_2153873_2156096_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP025598.1_2156133_2156577_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP025598.1_2156690_2157284_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP025598.1_2157366_2157972_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP025598.1_2158071_2159076_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP025598.1_2159175_2159928_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP025598.1_2159905_2160313_-	NA	NA|368aa|up_2|NZ_CP025598.1_2160447_2161551_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP025598.1_2161550_2162747_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP025598.1_2162916_2167296_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP025598.1_2171075_2171540_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP025598.1_2171637_2172501_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP025598.1_2172538_2173810_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP025598.1_2174081_2175197_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP025598.1_2175187_2176528_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP025598.1_2176564_2176945_-	NA	NA|621aa|down_6|NZ_CP025598.1_2177101_2178964_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP025598.1_2178971_2179451_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP025598.1_2179687_2180461_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP025598.1_2180464_2181232_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	11	3119190-3120544	3,7,3	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-D,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-A,TypeIII-D,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP025598.1_3112469_3112724_-,NA|135aa|up_7|NZ_CP025598.1_3112871_3113276_+,NA|64aa|up_6|NZ_CP025598.1_3113272_3113464_+,NA|86aa|up_4|NZ_CP025598.1_3115050_3115308_+,NA|104aa|up_3|NZ_CP025598.1_3115412_3115724_+,NA|203aa|up_2|NZ_CP025598.1_3116143_3116752_+,NA	NA|92aa|up_9|NZ_CP025598.1_3112018_3112294_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP025598.1_3112469_3112724_-	NA	NA|135aa|up_7|NZ_CP025598.1_3112871_3113276_+	NA	NA|64aa|up_6|NZ_CP025598.1_3113272_3113464_+	NA	NA|385aa|up_5|NZ_CP025598.1_3113662_3114817_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP025598.1_3115050_3115308_+	NA	NA|104aa|up_3|NZ_CP025598.1_3115412_3115724_+	NA	NA|203aa|up_2|NZ_CP025598.1_3116143_3116752_+	NA	NA|470aa|up_1|NZ_CP025598.1_3116822_3118232_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP025598.1_3118228_3119041_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP025598.1_3120570_3121832_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP025598.1_3123634_3123976_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP025598.1_3123976_3124993_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP025598.1_3125005_3126154_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP025598.1_3126249_3127377_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP025598.1_3127373_3128282_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP025598.1_3128262_3128973_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP025598.1_3128982_3129357_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP025598.1_3129353_3131792_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP025598.1_3131788_3132511_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	12	3121867-3123586	8,4,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-A,Type III-D,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-A,TypeIII-D,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP025598.1_3112469_3112724_-,NA|135aa|up_8|NZ_CP025598.1_3112871_3113276_+,NA|64aa|up_7|NZ_CP025598.1_3113272_3113464_+,NA|86aa|up_5|NZ_CP025598.1_3115050_3115308_+,NA|104aa|up_4|NZ_CP025598.1_3115412_3115724_+,NA|203aa|up_3|NZ_CP025598.1_3116143_3116752_+,NA	NA|85aa|up_9|NZ_CP025598.1_3112469_3112724_-	NA	NA|135aa|up_8|NZ_CP025598.1_3112871_3113276_+	NA	NA|64aa|up_7|NZ_CP025598.1_3113272_3113464_+	NA	NA|385aa|up_6|NZ_CP025598.1_3113662_3114817_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP025598.1_3115050_3115308_+	NA	NA|104aa|up_4|NZ_CP025598.1_3115412_3115724_+	NA	NA|203aa|up_3|NZ_CP025598.1_3116143_3116752_+	NA	NA|470aa|up_2|NZ_CP025598.1_3116822_3118232_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP025598.1_3118228_3119041_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP025598.1_3120570_3121832_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP025598.1_3123634_3123976_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP025598.1_3123976_3124993_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP025598.1_3125005_3126154_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP025598.1_3126249_3127377_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP025598.1_3127373_3128282_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP025598.1_3128262_3128973_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP025598.1_3128982_3129357_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP025598.1_3129353_3131792_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP025598.1_3131788_3132511_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP025598.1_3132910_3133456_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	13	3740705-3741246	5	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP025598.1_3755338_3755626_-,NA|87aa|down_9|NZ_CP025598.1_3768746_3769007_-	NA|282aa|up_9|NZ_CP025598.1_3719956_3720802_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP025598.1_3721276_3721717_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP025598.1_3721750_3722620_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP025598.1_3722640_3723651_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP025598.1_3723935_3724568_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP025598.1_3724634_3725864_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP025598.1_3726146_3727496_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP025598.1_3727507_3728647_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP025598.1_3728643_3729375_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_0|NZ_CP025598.1_3729383_3736955_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP025598.1_3743208_3743466_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP025598.1_3743721_3753195_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP025598.1_3753820_3754267_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP025598.1_3754303_3755044_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP025598.1_3755338_3755626_-	NA	NA|3717aa|down_5|NZ_CP025598.1_3755962_3767113_-	pfam00823, PPE, PPE family	NA|265aa|down_6|NZ_CP025598.1_3767356_3768151_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_7|NZ_CP025598.1_3768232_3768604_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_8|NZ_CP025598.1_3768501_3768720_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_9|NZ_CP025598.1_3768746_3769007_-	NA
GCF_002886685.1_ASM288668v1	NZ_CP025598	Mycobacterium tuberculosis strain GG-37-11 chromosome, complete genome	14	4110667-4110755	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP025598.1_4101253_4102024_-,NA|119aa|up_3|NZ_CP025598.1_4107158_4107515_+,NA|52aa|up_2|NZ_CP025598.1_4107614_4107770_+,NA|233aa|up_0|NZ_CP025598.1_4109771_4110470_-,NA|126aa|down_6|NZ_CP025598.1_4115990_4116368_+	NA|288aa|up_9|NZ_CP025598.1_4099635_4100499_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP025598.1_4101253_4102024_-	NA	NA|549aa|up_7|NZ_CP025598.1_4102020_4103667_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP025598.1_4103663_4104527_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP025598.1_4104519_4105446_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP025598.1_4105447_4107073_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP025598.1_4107158_4107515_+	NA	NA|52aa|up_2|NZ_CP025598.1_4107614_4107770_+	NA	NA|652aa|up_1|NZ_CP025598.1_4107780_4109736_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP025598.1_4109771_4110470_-	NA	NA|173aa|down_0|NZ_CP025598.1_4110815_4111334_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP025598.1_4111334_4112318_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP025598.1_4112310_4113504_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP025598.1_4113509_4114331_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP025598.1_4114462_4115146_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP025598.1_4115145_4115883_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP025598.1_4115990_4116368_+	NA	NA|225aa|down_7|NZ_CP025598.1_4116466_4117141_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP025598.1_4117246_4118041_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP025598.1_4118047_4118503_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
