assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	1	338028-338250	1	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	43	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|61aa|up_1|NZ_CP025596.1_333101_333284_-,NA	NA|561aa|up_9|NZ_CP025596.1_324508_326191_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_8|NZ_CP025596.1_326207_328403_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_7|NZ_CP025596.1_328516_329650_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_6|NZ_CP025596.1_329646_330267_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_5|NZ_CP025596.1_330363_330945_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_4|NZ_CP025596.1_330874_331600_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_3|NZ_CP025596.1_331689_332610_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_2|NZ_CP025596.1_332649_333078_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_1|NZ_CP025596.1_333101_333284_-	NA	NA|949aa|up_0|NZ_CP025596.1_333378_336225_-	pfam00934, PE, PE family	NA|537aa|down_0|NZ_CP025596.1_339287_340898_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_1|NZ_CP025596.1_340921_341830_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_2|NZ_CP025596.1_342053_343949_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_3|NZ_CP025596.1_343945_345562_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_4|NZ_CP025596.1_345558_349551_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_5|NZ_CP025596.1_349547_349856_+	pfam00934, PE, PE family	NA|514aa|down_6|NZ_CP025596.1_349858_351400_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_7|NZ_CP025596.1_351448_351742_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target	NA|97aa|down_8|NZ_CP025596.1_351771_352062_+	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown]	NA|296aa|down_9|NZ_CP025596.1_352072_352960_+	pfam14011, ESX-1_EspG, EspG family
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	2	366387-367085	1	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	366675-366716|366750-366782	NZ_CP025596.1_374706-374747|NZ_CP025596.1_373521-373553	NA	10	10	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|101aa|up_4|NZ_CP025596.1_363399_363702_+,NA|161aa|down_1|NZ_CP025596.1_376495_376978_-,NA|410aa|down_5|NZ_CP025596.1_379094_380324_+	NA|262aa|up_9|NZ_CP025596.1_358094_358880_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP025596.1_358868_359672_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP025596.1_359681_361079_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP025596.1_361257_363033_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP025596.1_363175_363403_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP025596.1_363399_363702_+	NA	NA|74aa|up_3|NZ_CP025596.1_363749_363971_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP025596.1_363967_364393_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP025596.1_364528_365161_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP025596.1_365157_366066_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP025596.1_375836_376508_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP025596.1_376495_376978_-	NA	NA|239aa|down_2|NZ_CP025596.1_377035_377752_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP025596.1_377853_378510_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP025596.1_378579_379071_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP025596.1_379094_380324_+	NA	NA|621aa|down_6|NZ_CP025596.1_380478_382341_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP025596.1_382412_382799_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|221aa|down_8|NZ_CP025596.1_382801_383464_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP025596.1_383524_384409_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	3	631180-631317	1	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGACCACGCCGGTG	18	2	3	631198-631215|631198-631215|631282-631299	NZ_CP025596.1_22466-22483|NZ_CP025596.1_1411966-1411983|NZ_CP025596.1_973139-973156	NA	3	3	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|54aa|up_7|NZ_CP025596.1_622018_622180_-,NA|478aa|up_0|NZ_CP025596.1_628195_629629_-,NA|450aa|down_2|NZ_CP025596.1_632952_634302_-,NA|93aa|down_5|NZ_CP025596.1_635832_636111_-	NA|325aa|up_9|NZ_CP025596.1_619788_620763_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP025596.1_620804_622022_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP025596.1_622018_622180_-	NA	NA|106aa|up_6|NZ_CP025596.1_622226_622544_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|595aa|up_5|NZ_CP025596.1_622690_624475_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP025596.1_624370_625378_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP025596.1_625459_626338_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP025596.1_626354_627149_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP025596.1_627145_628186_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP025596.1_628195_629629_-	NA	NA|211aa|down_0|NZ_CP025596.1_631640_632273_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP025596.1_632269_632932_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP025596.1_632952_634302_-	NA	NA|381aa|down_3|NZ_CP025596.1_634313_635456_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP025596.1_635470_635773_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP025596.1_635832_636111_-	NA	NA|418aa|down_6|NZ_CP025596.1_636107_637361_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP025596.1_637480_637867_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP025596.1_637929_638814_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP025596.1_638909_639812_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	4	691923-691999	2	CRISPRCasFinder	no	c2c9_V-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|72aa|up_9|NZ_CP025596.1_677607_677823_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP025596.1_677819_678227_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP025596.1_678286_678973_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_6|NZ_CP025596.1_679126_681760_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_5|NZ_CP025596.1_681782_684170_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_4|NZ_CP025596.1_684307_685030_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_3|NZ_CP025596.1_685026_685824_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_2|NZ_CP025596.1_685825_686713_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_1|NZ_CP025596.1_686718_687933_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|482aa|up_0|NZ_CP025596.1_688956_690402_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP025596.1_693134_694685_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP025596.1_694736_695129_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP025596.1_695125_695383_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP025596.1_695565_696801_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP025596.1_697051_697465_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP025596.1_697461_697698_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP025596.1_697801_698308_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP025596.1_698421_698892_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP025596.1_698935_699697_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP025596.1_699753_700065_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	5	926510-927457	2	CRT	no	csa3	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	927293-927328|927293-927328|927293-927328	NZ_CP025596.1_675026-674991|NZ_CP025596.1_1213656-1213691|NZ_CP025596.1_2423697-2423662	NA	19	19	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|184aa|down_2|NZ_CP025596.1_931458_932010_-,NA|81aa|down_8|NZ_CP025596.1_937473_937716_+	NA|685aa|up_9|NZ_CP025596.1_914146_916201_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP025596.1_916366_917536_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP025596.1_917623_918640_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_6|NZ_CP025596.1_918801_919443_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP025596.1_919523_920579_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP025596.1_920630_921023_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP025596.1_921080_921503_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP025596.1_921464_921755_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP025596.1_921859_922765_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP025596.1_922783_923599_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|880aa|down_0|NZ_CP025596.1_927726_930366_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP025596.1_930833_931478_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP025596.1_931458_932010_-	NA	NA|218aa|down_3|NZ_CP025596.1_932159_932813_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP025596.1_932883_933912_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP025596.1_934600_935371_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP025596.1_935457_936270_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|287aa|down_7|NZ_CP025596.1_936337_937198_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_8|NZ_CP025596.1_937473_937716_+	NA	NA|431aa|down_9|NZ_CP025596.1_937992_939285_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	6	1191223-1191331	3	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA	NA|544aa|up_9|NZ_CP025596.1_1180590_1182222_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP025596.1_1182297_1183362_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP025596.1_1183414_1183888_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP025596.1_1183921_1184785_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP025596.1_1184789_1185647_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP025596.1_1185647_1186730_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP025596.1_1186810_1187230_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP025596.1_1187341_1187908_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP025596.1_1187904_1188300_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|668aa|up_0|NZ_CP025596.1_1188327_1190331_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP025596.1_1192416_1194180_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP025596.1_1194176_1194950_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP025596.1_1194961_1195999_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP025596.1_1196185_1197022_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP025596.1_1197137_1197989_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP025596.1_1198062_1199280_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP025596.1_1199332_1200277_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP025596.1_1200499_1201567_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP025596.1_1201623_1203018_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP025596.1_1203219_1203942_+	pfam06271, RDD, RDD family
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	7	1211857-1212713	4	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GGCGGTGTCGGCGGTGCCGGCGG	23	4	74	1212240-1212261|1212285-1212300|1212423-1212444|1212423-1212444|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558|1212540-1212558	NZ_CP025596.1_2960463-2960442|NZ_CP025596.1_2088529-2088514|NZ_CP025596.1_837332-837353|NZ_CP025596.1_1217551-1217572|NZ_CP025596.1_674690-674672|NZ_CP025596.1_1213383-1213401|NZ_CP025596.1_1217524-1217542|NZ_CP025596.1_1217596-1217614|NZ_CP025596.1_1630603-1630585|NZ_CP025596.1_1633429-1633411|NZ_CP025596.1_1990725-1990707|NZ_CP025596.1_2061457-2061439|NZ_CP025596.1_2061904-2061886|NZ_CP025596.1_2062003-2061985|NZ_CP025596.1_2802011-2801993|NZ_CP025596.1_2805539-2805521|NZ_CP025596.1_150128-150146|NZ_CP025596.1_333724-333706|NZ_CP025596.1_335143-335125|NZ_CP025596.1_335596-335578|NZ_CP025596.1_335647-335629|NZ_CP025596.1_335656-335638|NZ_CP025596.1_337927-337909|NZ_CP025596.1_338323-338305|NZ_CP025596.1_338352-338370|NZ_CP025596.1_338446-338428|NZ_CP025596.1_362977-362959|NZ_CP025596.1_443350-443332|NZ_CP025596.1_546692-546674|NZ_CP025596.1_623881-623899|NZ_CP025596.1_624103-624121|NZ_CP025596.1_673856-673838|NZ_CP025596.1_840067-840085|NZ_CP025596.1_840116-840134|NZ_CP025596.1_1090886-1090904|NZ_CP025596.1_1091534-1091552|NZ_CP025596.1_1095592-1095574|NZ_CP025596.1_1212912-1212930|NZ_CP025596.1_1213302-1213320|NZ_CP025596.1_1217944-1217962|NZ_CP025596.1_1489110-1489092|NZ_CP025596.1_1618567-1618549|NZ_CP025596.1_1619020-1619002|NZ_CP025596.1_1635942-1635924|NZ_CP025596.1_1635951-1635933|NZ_CP025596.1_1864229-1864211|NZ_CP025596.1_1864757-1864739|NZ_CP025596.1_1989999-1989981|NZ_CP025596.1_2001361-2001379|NZ_CP025596.1_2088727-2088709|NZ_CP025596.1_2303420-2303402|NZ_CP025596.1_2356873-2356855|NZ_CP025596.1_2419526-2419544|NZ_CP025596.1_2423610-2423592|NZ_CP025596.1_2569094-2569076|NZ_CP025596.1_2693381-2693399|NZ_CP025596.1_2795326-2795308|NZ_CP025596.1_2795908-2795890|NZ_CP025596.1_3054499-3054517|NZ_CP025596.1_3054598-3054616|NZ_CP025596.1_3705412-3705430|NZ_CP025596.1_3737386-3737368|NZ_CP025596.1_3738010-3737992|NZ_CP025596.1_3738253-3738235|NZ_CP025596.1_3738386-3738368|NZ_CP025596.1_3802274-3802292|NZ_CP025596.1_3802457-3802475|NZ_CP025596.1_3802625-3802643|NZ_CP025596.1_3930416-3930434|NZ_CP025596.1_3932146-3932164|NZ_CP025596.1_3940644-3940662|NZ_CP025596.1_4031619-4031601|NZ_CP025596.1_4094145-4094163|NZ_CP025596.1_4094235-4094253	NA	16	16	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|89aa|up_3|NZ_CP025596.1_1207289_1207556_+,NA|61aa|down_3|NZ_CP025596.1_1215131_1215314_+,NA|35aa|down_4|NZ_CP025596.1_1215423_1215528_+	NA|465aa|up_9|NZ_CP025596.1_1201623_1203018_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|up_8|NZ_CP025596.1_1203219_1203942_+	pfam06271, RDD, RDD family	NA|389aa|up_7|NZ_CP025596.1_1203973_1205140_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|165aa|up_6|NZ_CP025596.1_1205210_1205705_-	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|145aa|up_5|NZ_CP025596.1_1205890_1206325_-	pfam14155, DUF4307, Domain of unknown function (DUF4307)	NA|289aa|up_4|NZ_CP025596.1_1206426_1207293_+	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca	NA|89aa|up_3|NZ_CP025596.1_1207289_1207556_+	NA	NA|674aa|up_2|NZ_CP025596.1_1207542_1209564_+	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]	NA|243aa|up_1|NZ_CP025596.1_1209662_1210391_-	TIGR01065, Hypothetical_UPF0073_protein_yqfA	NA|263aa|up_0|NZ_CP025596.1_1210501_1211290_+	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional	NA|107aa|down_0|NZ_CP025596.1_1213946_1214267_+	COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]	NA|145aa|down_1|NZ_CP025596.1_1214419_1214854_+	pfam00934, PE, PE family	NA|55aa|down_2|NZ_CP025596.1_1214955_1215120_+	smart00637, CBD_II, CBD_II domain	NA|61aa|down_3|NZ_CP025596.1_1215131_1215314_+	NA	NA|35aa|down_4|NZ_CP025596.1_1215423_1215528_+	NA	NA|152aa|down_5|NZ_CP025596.1_1215505_1215961_+	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12	NA|851aa|down_6|NZ_CP025596.1_1216375_1218928_+	pfam00934, PE, PE family	NA|313aa|down_7|NZ_CP025596.1_1219145_1220084_-	PRK05439, PRK05439, pantothenate kinase; Provisional	NA|427aa|down_8|NZ_CP025596.1_1220471_1221752_+	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed	NA|276aa|down_9|NZ_CP025596.1_1221856_1222684_+	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	8	1572085-1573157	5	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	0	0	NA	NA	NA	15	15	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|106aa|up_7|NZ_CP025596.1_1563848_1564166_+,NA	NA|103aa|up_9|NZ_CP025596.1_1561363_1561672_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP025596.1_1561668_1563288_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP025596.1_1563848_1564166_+	NA	NA|209aa|up_6|NZ_CP025596.1_1564300_1564927_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP025596.1_1564992_1565325_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP025596.1_1565340_1566597_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP025596.1_1566724_1567936_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP025596.1_1568008_1569487_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP025596.1_1569483_1570869_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP025596.1_1570946_1571981_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP025596.1_1574010_1574412_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP025596.1_1574408_1574666_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP025596.1_1574748_1575708_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP025596.1_1575732_1576695_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP025596.1_1576828_1577431_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP025596.1_1577511_1579479_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP025596.1_1579496_1580321_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP025596.1_1580489_1580972_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP025596.1_1581043_1581868_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP025596.1_1582064_1583003_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	9	1636520-1636746	2	PILER-CR	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CGGCGGCGCCGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCCG	47	0	0	NA	NA	NA	2	2	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|38aa|up_8|NZ_CP025596.1_1623028_1623142_-,NA|137aa|up_7|NZ_CP025596.1_1623191_1623602_-,NA|288aa|down_2|NZ_CP025596.1_1640584_1641448_+	NA|162aa|up_9|NZ_CP025596.1_1622111_1622597_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP025596.1_1623028_1623142_-	NA	NA|137aa|up_7|NZ_CP025596.1_1623191_1623602_-	NA	NA|248aa|up_6|NZ_CP025596.1_1623618_1624362_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|304aa|up_5|NZ_CP025596.1_1624358_1625270_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP025596.1_1625322_1626867_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP025596.1_1626863_1627985_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP025596.1_1628001_1630104_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1330aa|up_1|NZ_CP025596.1_1630542_1634532_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP025596.1_1634933_1635860_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP025596.1_1638285_1639551_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP025596.1_1639578_1640565_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP025596.1_1640584_1641448_+	NA	NA|311aa|down_3|NZ_CP025596.1_1641397_1642330_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP025596.1_1642441_1643227_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP025596.1_1643223_1644165_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP025596.1_1644267_1646043_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP025596.1_1646090_1646897_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP025596.1_1646893_1649434_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP025596.1_1649430_1650624_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	10	2088199-2088453	3	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	2088280-2088297|2088280-2088297|2088370-2088387	NZ_CP025596.1_401002-400985|NZ_CP025596.1_607336-607319|NZ_CP025596.1_3450109-3450092	NA	5	5	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|88aa|up_0|NZ_CP025596.1_2087558_2087822_-,NA	NA|165aa|up_9|NZ_CP025596.1_2073852_2074347_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP025596.1_2074750_2075428_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP025596.1_2075786_2078612_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP025596.1_2078838_2079699_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP025596.1_2079739_2080606_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP025596.1_2080610_2082497_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP025596.1_2082512_2084546_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP025596.1_2084665_2086891_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP025596.1_2087166_2087562_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP025596.1_2087558_2087822_-	NA	NA|346aa|down_0|NZ_CP025596.1_2089590_2090628_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP025596.1_2090627_2091995_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP025596.1_2092168_2093605_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP025596.1_2093640_2095092_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP025596.1_2095121_2096072_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP025596.1_2096086_2096503_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP025596.1_2096780_2097203_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP025596.1_2097251_2097554_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP025596.1_2097550_2097865_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP025596.1_2097864_2099598_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	11	2168744-2168963	6	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|136aa|up_3|NZ_CP025596.1_2159850_2160258_-,NA|127aa|down_5|NZ_CP025596.1_2176479_2176860_-	NA|741aa|up_9|NZ_CP025596.1_2153818_2156041_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_8|NZ_CP025596.1_2156078_2156522_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_7|NZ_CP025596.1_2156635_2157229_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_6|NZ_CP025596.1_2157311_2157917_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_5|NZ_CP025596.1_2158016_2159021_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_4|NZ_CP025596.1_2159120_2159873_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_3|NZ_CP025596.1_2159850_2160258_-	NA	NA|368aa|up_2|NZ_CP025596.1_2160392_2161496_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|399aa|up_1|NZ_CP025596.1_2161495_2162692_+	COG2224, AceA, Isocitrate lyase [Energy production and conversion]	NA|1460aa|up_0|NZ_CP025596.1_2162861_2167241_-	pfam00823, PPE, PPE family	NA|155aa|down_0|NZ_CP025596.1_2170990_2171455_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP025596.1_2171552_2172416_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP025596.1_2172453_2173725_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP025596.1_2173996_2175112_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP025596.1_2175102_2176443_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP025596.1_2176479_2176860_-	NA	NA|621aa|down_6|NZ_CP025596.1_2177016_2178879_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP025596.1_2178886_2179366_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP025596.1_2179602_2180376_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|215aa|down_9|NZ_CP025596.1_2181169_2181814_-	TIGR03085, TIGR03085, TIGR03085 family protein
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	12	3119087-3120440	3,7,4	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	17,17,18	18	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_8|NZ_CP025596.1_3112366_3112621_-,NA|135aa|up_7|NZ_CP025596.1_3112768_3113173_+,NA|64aa|up_6|NZ_CP025596.1_3113169_3113361_+,NA|86aa|up_4|NZ_CP025596.1_3114947_3115205_+,NA|104aa|up_3|NZ_CP025596.1_3115309_3115621_+,NA|203aa|up_2|NZ_CP025596.1_3116040_3116649_+,NA	NA|92aa|up_9|NZ_CP025596.1_3111915_3112191_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP025596.1_3112366_3112621_-	NA	NA|135aa|up_7|NZ_CP025596.1_3112768_3113173_+	NA	NA|64aa|up_6|NZ_CP025596.1_3113169_3113361_+	NA	NA|385aa|up_5|NZ_CP025596.1_3113559_3114714_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP025596.1_3114947_3115205_+	NA	NA|104aa|up_3|NZ_CP025596.1_3115309_3115621_+	NA	NA|203aa|up_2|NZ_CP025596.1_3116040_3116649_+	NA	NA|470aa|up_1|NZ_CP025596.1_3116719_3118129_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP025596.1_3118125_3118938_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP025596.1_3120466_3121728_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP025596.1_3123527_3123869_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP025596.1_3123869_3124886_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP025596.1_3124898_3126047_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP025596.1_3126142_3127270_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP025596.1_3127266_3128175_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP025596.1_3128155_3128866_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP025596.1_3128875_3129250_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP025596.1_3129246_3131685_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_9|NZ_CP025596.1_3131681_3132404_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	13	3121763-3123479	8,5,4	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	23,23,22	23	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|85aa|up_9|NZ_CP025596.1_3112366_3112621_-,NA|135aa|up_8|NZ_CP025596.1_3112768_3113173_+,NA|64aa|up_7|NZ_CP025596.1_3113169_3113361_+,NA|86aa|up_5|NZ_CP025596.1_3114947_3115205_+,NA|104aa|up_4|NZ_CP025596.1_3115309_3115621_+,NA|203aa|up_3|NZ_CP025596.1_3116040_3116649_+,NA	NA|85aa|up_9|NZ_CP025596.1_3112366_3112621_-	NA	NA|135aa|up_8|NZ_CP025596.1_3112768_3113173_+	NA	NA|64aa|up_7|NZ_CP025596.1_3113169_3113361_+	NA	NA|385aa|up_6|NZ_CP025596.1_3113559_3114714_+	pfam00665, rve, Integrase core domain	NA|86aa|up_5|NZ_CP025596.1_3114947_3115205_+	NA	NA|104aa|up_4|NZ_CP025596.1_3115309_3115621_+	NA	NA|203aa|up_3|NZ_CP025596.1_3116040_3116649_+	NA	NA|470aa|up_2|NZ_CP025596.1_3116719_3118129_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP025596.1_3118125_3118938_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP025596.1_3120466_3121728_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP025596.1_3123527_3123869_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP025596.1_3123869_3124886_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP025596.1_3124898_3126047_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP025596.1_3126142_3127270_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP025596.1_3127266_3128175_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP025596.1_3128155_3128866_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP025596.1_3128875_3129250_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP025596.1_3129246_3131685_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_8|NZ_CP025596.1_3131681_3132404_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP025596.1_3132803_3133349_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	14	3740598-3741139	6	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|96aa|down_4|NZ_CP025596.1_3755240_3755528_-,NA|87aa|down_8|NZ_CP025596.1_3768649_3768910_-	NA|282aa|up_9|NZ_CP025596.1_3719834_3720680_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP025596.1_3721154_3721595_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP025596.1_3721628_3722498_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP025596.1_3722518_3723529_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP025596.1_3723813_3724446_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP025596.1_3724512_3725742_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP025596.1_3726024_3727374_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP025596.1_3727385_3728525_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP025596.1_3728521_3729253_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2523aa|up_0|NZ_CP025596.1_3729261_3736830_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP025596.1_3743110_3743368_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP025596.1_3743623_3753097_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP025596.1_3753722_3754169_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP025596.1_3754205_3754946_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP025596.1_3755240_3755528_-	NA	NA|265aa|down_5|NZ_CP025596.1_3767259_3768054_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_CP025596.1_3768135_3768507_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_7|NZ_CP025596.1_3768404_3768623_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_CP025596.1_3768649_3768910_-	NA	NA|130aa|down_9|NZ_CP025596.1_3769024_3769414_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	15	3948260-3948766	7	CRT	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	CACCGGCGGCACCGGCGGCNCNGGCGGCACCGGCGGCNA	39	4	7	3948299-3948349|3948299-3948349|3948389-3948424|3948389-3948424|3948464-3948496|3948464-3948496|3948677-3948727	NZ_CP025596.1_3948899-3948949|NZ_CP025596.1_3949516-3949566|NZ_CP025596.1_3948989-3949024|NZ_CP025596.1_3949606-3949641|NZ_CP025596.1_3949064-3949096|NZ_CP025596.1_3949681-3949713|NZ_CP025596.1_3949280-3949330	NA	6	6	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA,NA|280aa|down_2|NZ_CP025596.1_3953325_3954165_+	NA|64aa|up_9|NZ_CP025596.1_3921979_3922171_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_8|NZ_CP025596.1_3922385_3923588_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_7|NZ_CP025596.1_3923612_3924734_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_6|NZ_CP025596.1_3924804_3926313_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1376aa|up_5|NZ_CP025596.1_3926483_3930611_+	pfam00934, PE, PE family	NA|1899aa|up_4|NZ_CP025596.1_3930901_3936598_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP025596.1_3936764_3938312_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP025596.1_3938308_3939145_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1782aa|up_1|NZ_CP025596.1_3939504_3944850_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP025596.1_3944978_3945635_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP025596.1_3950718_3952365_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP025596.1_3952438_3953230_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP025596.1_3953325_3954165_+	NA	NA|399aa|down_3|NZ_CP025596.1_3954219_3955416_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP025596.1_3955444_3956155_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP025596.1_3956219_3957263_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP025596.1_3957415_3958327_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP025596.1_3958342_3959407_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP025596.1_3959423_3960608_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP025596.1_3960649_3961681_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_002886945.1_ASM288694v1	NZ_CP025596	Mycobacterium tuberculosis strain GG-27-11 chromosome, complete genome	16	4110580-4110668	9	CRISPRCasFinder	no		RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	RT,csa3,c2c9_V-U4,cas3,DinG,WYL,cas4,DEDDh,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	NA|257aa|up_8|NZ_CP025596.1_4101166_4101937_-,NA|119aa|up_3|NZ_CP025596.1_4107071_4107428_+,NA|52aa|up_2|NZ_CP025596.1_4107527_4107683_+,NA|233aa|up_0|NZ_CP025596.1_4109684_4110383_-,NA|126aa|down_6|NZ_CP025596.1_4115903_4116281_+	NA|288aa|up_9|NZ_CP025596.1_4099548_4100412_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP025596.1_4101166_4101937_-	NA	NA|549aa|up_7|NZ_CP025596.1_4101933_4103580_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP025596.1_4103576_4104440_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP025596.1_4104432_4105359_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP025596.1_4105360_4106986_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP025596.1_4107071_4107428_+	NA	NA|52aa|up_2|NZ_CP025596.1_4107527_4107683_+	NA	NA|652aa|up_1|NZ_CP025596.1_4107693_4109649_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP025596.1_4109684_4110383_-	NA	NA|173aa|down_0|NZ_CP025596.1_4110728_4111247_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP025596.1_4111247_4112231_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP025596.1_4112223_4113417_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP025596.1_4113422_4114244_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP025596.1_4114375_4115059_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP025596.1_4115058_4115796_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP025596.1_4115903_4116281_+	NA	NA|225aa|down_7|NZ_CP025596.1_4116379_4117054_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP025596.1_4117159_4117954_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP025596.1_4117960_4118416_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
