assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	1	487501-487602	1	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	CTGCGGCCAGGGAGCCTGTCCCCGC	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA|54aa|up_3|NZ_CP020819.1_479153_479315_+,NA	NA|112aa|up_9|NZ_CP020819.1_468810_469146_-	pfam07411, DUF1508, Domain of unknown function (DUF1508)	NA|382aa|up_8|NZ_CP020819.1_469286_470432_-	cd06812, PLPDE_III_DSD_D-TA_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1	NA|220aa|up_7|NZ_CP020819.1_470458_471118_-	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase	NA|303aa|up_6|NZ_CP020819.1_471209_472118_+	cd08479, PBP2_CrgA_like_9, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold	NA|61aa|up_5|NZ_CP020819.1_472114_472297_+	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain	NA|2153aa|up_4|NZ_CP020819.1_472610_479069_+	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain	NA|54aa|up_3|NZ_CP020819.1_479153_479315_+	NA	NA|44aa|up_2|NZ_CP020819.1_479346_479478_+	COG5510, COG5510, Predicted small secreted protein [Function unknown]	NA|2300aa|up_1|NZ_CP020819.1_479924_486824_+	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain	NA|200aa|up_0|NZ_CP020819.1_486857_487457_+	cd20298, cupin_UAH, ureidoglycolate amidohydrolase (UAH) and related proteins, cupin domain	NA|326aa|down_0|NZ_CP020819.1_487883_488861_+	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold	NA|525aa|down_1|NZ_CP020819.1_488874_490449_+	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|247aa|down_2|NZ_CP020819.1_490456_491197_+	COG1414, IclR, Transcriptional regulator [Transcription]	NA|255aa|down_3|NZ_CP020819.1_491220_491985_+	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily	NA|112aa|down_4|NZ_CP020819.1_492029_492365_+	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]	NA|327aa|down_5|NZ_CP020819.1_492418_493399_+	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family;  contains the type 2 periplasmic binding fold	NA|185aa|down_6|NZ_CP020819.1_493498_494053_+	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases	NA|418aa|down_7|NZ_CP020819.1_494144_495398_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|321aa|down_8|NZ_CP020819.1_495375_496338_-	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold	NA|159aa|down_9|NZ_CP020819.1_496490_496967_+	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	2	1003913-1003997	2	CRISPRCasFinder	no	csa3	csa3,DEDDh,DinG,cas3	Type I-A	GGTGCCTGTCCCCGCGGGGACAG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|169aa|up_9|NZ_CP020819.1_994034_994541_-	cd08896, SRPBCC_CalC_Aha1-like_3, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins	csa3|113aa|up_8|NZ_CP020819.1_994537_994876_-	COG0640, ArsR, Predicted transcriptional regulators [Transcription]	NA|840aa|up_7|NZ_CP020819.1_995304_997824_+	PRK10833, PRK10833, putative assembly protein; Provisional	NA|129aa|up_6|NZ_CP020819.1_997820_998207_+	pfam03476, MOSC_N, MOSC N-terminal beta barrel domain	NA|406aa|up_5|NZ_CP020819.1_998214_999432_-	pfam03594, BenE, Benzoate membrane transport protein	NA|84aa|up_4|NZ_CP020819.1_999428_999680_-	cd10549, MtMvhB_like, Uncharacterized polyferredoxin-like protein	NA|170aa|up_3|NZ_CP020819.1_999734_1000244_-	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional	NA|207aa|up_2|NZ_CP020819.1_1000264_1000885_-	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair]	NA|402aa|up_1|NZ_CP020819.1_1000954_1002160_+	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional	NA|533aa|up_0|NZ_CP020819.1_1002206_1003805_-	cd07756, CYTH-like_Pase_CHAD, Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain	NA|274aa|down_0|NZ_CP020819.1_1004043_1004865_-	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE	NA|297aa|down_1|NZ_CP020819.1_1004861_1005752_-	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE	NA|257aa|down_2|NZ_CP020819.1_1005748_1006519_-	cd03256, ABC_PhnC_transporter, ATP-binding cassette domain of the binding protein-dependent phosphonate transport system	NA|336aa|down_3|NZ_CP020819.1_1006521_1007529_-	cd13573, PBP2_PnhD_3, Substrate binding domain of uncharacterized ABC-type phosphonate-like transporter; contains the type 2 periplasmic binding fold	NA|276aa|down_4|NZ_CP020819.1_1007677_1008505_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|266aa|down_5|NZ_CP020819.1_1008510_1009308_-	TIGR01484, Putative_mannosyl-3-phosphoglycerate_phosphatase, HAD-superfamily hydrolase, subfamily IIB	NA|392aa|down_6|NZ_CP020819.1_1009453_1010629_+	PRK14019, PRK14019, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	NA|176aa|down_7|NZ_CP020819.1_1010642_1011170_+	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional	NA|155aa|down_8|NZ_CP020819.1_1011177_1011642_+	PRK00202, nusB, transcription antitermination factor NusB	NA|339aa|down_9|NZ_CP020819.1_1011681_1012698_+	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	3	1530026-1530112	3	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	AGTGTGCCTGTCCCCGCAGGGACAG	25	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA|106aa|down_5|NZ_CP020819.1_1536036_1536354_-	NA|109aa|up_9|NZ_CP020819.1_1518354_1518681_+	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein	NA|203aa|up_8|NZ_CP020819.1_1518730_1519339_+	PRK00076, recR, recombination protein RecR; Reviewed	NA|417aa|up_7|NZ_CP020819.1_1519413_1520664_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|347aa|up_6|NZ_CP020819.1_1520769_1521810_+	cd13649, PBP2_Cae31940, Substrate binding domain of an uncharacterized protein similar to ABC-type transporter for thiamin biosynthetic pathway intermediates; a member of the type 2 periplasmic binding fold superfamily	NA|270aa|up_5|NZ_CP020819.1_1521802_1522612_+	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]	NA|265aa|up_4|NZ_CP020819.1_1522615_1523410_+	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]	NA|328aa|up_3|NZ_CP020819.1_1523451_1524435_-	PRK05269, PRK05269, transaldolase B; Provisional	NA|366aa|up_2|NZ_CP020819.1_1524697_1525795_+	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit	NA|1081aa|up_1|NZ_CP020819.1_1525805_1529048_+	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|255aa|up_0|NZ_CP020819.1_1529198_1529963_+	PRK07024, PRK07024, SDR family oxidoreductase	NA|215aa|down_0|NZ_CP020819.1_1530143_1530788_-	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1)	NA|300aa|down_1|NZ_CP020819.1_1530798_1531698_-	COG0583, LysR, Transcriptional regulator [Transcription]	NA|362aa|down_2|NZ_CP020819.1_1531745_1532831_-	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|570aa|down_3|NZ_CP020819.1_1532827_1534537_-	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]	NA|441aa|down_4|NZ_CP020819.1_1534613_1535936_-	cd13518, PBP2_Fe3_thiamine_like, Substrate binding domain of iron and thiamine transporters-like, a member of the type 2 periplasmic binding fold superfamily	NA|106aa|down_5|NZ_CP020819.1_1536036_1536354_-	NA	NA|438aa|down_6|NZ_CP020819.1_1536487_1537801_+	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G	NA|546aa|down_7|NZ_CP020819.1_1537831_1539469_-	PRK15041, PRK15041, methyl-accepting chemotaxis protein	NA|159aa|down_8|NZ_CP020819.1_1540092_1540569_+	PRK00226, greA, transcription elongation factor GreA; Reviewed	NA|201aa|down_9|NZ_CP020819.1_1540923_1541526_-	smart01103, CRS1_YhbY, Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	4	2351665-2351826	4	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GGTGGAAGTCGTGCCGCGGCCGAAGGTCGAAACGGCCCAGCCGCTTCCGCCCCG	54	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|303aa|up_9|NZ_CP020819.1_2328107_2329016_+	COG0583, LysR, Transcriptional regulator [Transcription]	NA|350aa|up_8|NZ_CP020819.1_2329358_2330408_+	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold	NA|207aa|up_7|NZ_CP020819.1_2330517_2331138_+	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component	NA|428aa|up_6|NZ_CP020819.1_2331134_2332418_+	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]	NA|240aa|up_5|NZ_CP020819.1_2332440_2333160_+	pfam11010, DUF2848, Protein of unknown function (DUF2848)	NA|450aa|up_4|NZ_CP020819.1_2333220_2334570_+	PRK07056, PRK07056, amidase; Provisional	NA|278aa|up_3|NZ_CP020819.1_2334588_2335422_+	PRK05463, PRK05463, putative hydro-lyase	NA|292aa|up_2|NZ_CP020819.1_2335555_2336431_+	pfam00563, EAL, EAL domain	NA|1239aa|up_1|NZ_CP020819.1_2336477_2340194_-	PRK09959, PRK09959, acid-sensing system histidine kinase EvgS	NA|210aa|up_0|NZ_CP020819.1_2340202_2340832_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|202aa|down_0|NZ_CP020819.1_2352813_2353419_+	pfam16970, FimA, Type-1 fimbrial protein, A	NA|245aa|down_1|NZ_CP020819.1_2353668_2354403_+	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]	NA|874aa|down_2|NZ_CP020819.1_2354465_2357087_+	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]	NA|366aa|down_3|NZ_CP020819.1_2357100_2358198_+	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]	NA|584aa|down_4|NZ_CP020819.1_2358190_2359942_+	pfam03865, ShlB, Haemolysin secretion/activation protein ShlB/FhaC/HecB	NA|434aa|down_5|NZ_CP020819.1_2359967_2361269_-	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit	NA|167aa|down_6|NZ_CP020819.1_2361261_2361762_-	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component	NA|362aa|down_7|NZ_CP020819.1_2361768_2362854_-	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold	NA|433aa|down_8|NZ_CP020819.1_2363006_2364305_-	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit	NA|164aa|down_9|NZ_CP020819.1_2364297_2364789_-	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	5	3129255-3129382	5	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GCCCCCACGCTGCGCCCGCTACGCGGGCTTGCTGCCCCCCGAG	43	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|621aa|up_9|NZ_CP020819.1_3119165_3121028_-	PRK05183, hscA, chaperone protein HscA; Provisional	NA|171aa|up_8|NZ_CP020819.1_3121157_3121670_-	PRK03578, hscB, Fe-S protein assembly co-chaperone HscB	NA|108aa|up_7|NZ_CP020819.1_3121672_3121996_-	TIGR02011, Protein_yfhF	NA|137aa|up_6|NZ_CP020819.1_3121997_3122408_-	PRK11325, PRK11325, scaffold protein; Provisional	NA|404aa|up_5|NZ_CP020819.1_3122441_3123653_-	PRK14012, PRK14012, IscS subfamily cysteine desulfurase	NA|171aa|up_4|NZ_CP020819.1_3123670_3124183_-	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR	NA|164aa|up_3|NZ_CP020819.1_3124398_3124890_-	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase	NA|676aa|up_2|NZ_CP020819.1_3125151_3127179_-	PRK05298, PRK05298, excinuclease ABC subunit UvrB	NA|401aa|up_1|NZ_CP020819.1_3127256_3128459_+	PRK09257, PRK09257, aromatic amino acid transaminase	NA|243aa|up_0|NZ_CP020819.1_3128509_3129238_+	PRK00215, PRK00215, transcriptional repressor LexA	NA|515aa|down_0|NZ_CP020819.1_3129467_3131012_-	TIGR01414, Contains:_AIDA-I_translocator, outer membrane autotransporter barrel domain	NA|321aa|down_1|NZ_CP020819.1_3131282_3132245_-	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family;  contains the type 2 periplasmic binding fold	NA|214aa|down_2|NZ_CP020819.1_3132279_3132921_-	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit	NA|239aa|down_3|NZ_CP020819.1_3132913_3133630_-	TIGR02429, 3-oxoadipate_CoA-transferase_subunit_A, 3-oxoacid CoA-transferase, A subunit	NA|332aa|down_4|NZ_CP020819.1_3133626_3134622_-	cd00567, ACAD, Acyl-CoA dehydrogenase	NA|388aa|down_5|NZ_CP020819.1_3134643_3135807_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|264aa|down_6|NZ_CP020819.1_3135803_3136595_-	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG	NA|386aa|down_7|NZ_CP020819.1_3136601_3137759_-	PRK06158, PRK06158, thiolase; Provisional	NA|144aa|down_8|NZ_CP020819.1_3137755_3138187_-	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|268aa|down_9|NZ_CP020819.1_3138183_3138987_-	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	6	3253251-3253366	6	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	TTTTTGCCTTGGGACGGCCCGGCGGCAAAAAAA	33	1	13	3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333|3253284-3253333	NZ_CP020819.1_1487010-1487059|NZ_CP020819.1_3095578-3095627|NZ_CP020819.1_3095661-3095710|NZ_CP020819.1_3095744-3095793|NZ_CP020819.1_3095827-3095876|NZ_CP020819.1_3095910-3095959|NZ_CP020819.1_3095993-3096042|NZ_CP020819.1_3096076-3096125|NZ_CP020819.1_1442441-1442392|NZ_CP020819.1_1442524-1442475|NZ_CP020819.1_3274321-3274272|NZ_CP020819.1_3274238-3274189|NZ_CP020819.1_3274404-3274355	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA|267aa|up_9|NZ_CP020819.1_3243569_3244370_+,NA|208aa|up_2|NZ_CP020819.1_3250857_3251481_-,NA|439aa|up_1|NZ_CP020819.1_3251477_3252794_-,NA|88aa|up_0|NZ_CP020819.1_3252790_3253054_-,NA	NA|267aa|up_9|NZ_CP020819.1_3243569_3244370_+	NA	NA|299aa|up_8|NZ_CP020819.1_3244591_3245488_-	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]	NA|282aa|up_7|NZ_CP020819.1_3245498_3246344_-	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion]	NA|539aa|up_6|NZ_CP020819.1_3246340_3247957_-	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]	NA|471aa|up_5|NZ_CP020819.1_3247953_3249366_-	pfam00263, Secretin, Bacterial type II and III secretion system protein	NA|282aa|up_4|NZ_CP020819.1_3249362_3250208_-	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB	NA|219aa|up_3|NZ_CP020819.1_3250204_3250861_-	PRK14852, PRK14852, hypothetical protein; Provisional	NA|208aa|up_2|NZ_CP020819.1_3250857_3251481_-	NA	NA|439aa|up_1|NZ_CP020819.1_3251477_3252794_-	NA	NA|88aa|up_0|NZ_CP020819.1_3252790_3253054_-	NA	NA|44aa|down_0|NZ_CP020819.1_3253411_3253543_-	COG5510, COG5510, Predicted small secreted protein [Function unknown]	NA|232aa|down_1|NZ_CP020819.1_3253569_3254265_-	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]	NA|179aa|down_2|NZ_CP020819.1_3254448_3254985_-	PRK01250, PRK01250, inorganic diphosphatase	NA|532aa|down_3|NZ_CP020819.1_3255013_3256609_-	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein	NA|395aa|down_4|NZ_CP020819.1_3256612_3257797_-	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed	NA|275aa|down_5|NZ_CP020819.1_3257834_3258659_-	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme	NA|315aa|down_6|NZ_CP020819.1_3258655_3259600_-	PRK00072, hemC, porphobilinogen deaminase; Reviewed	NA|240aa|down_7|NZ_CP020819.1_3259718_3260438_-	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family	NA|232aa|down_8|NZ_CP020819.1_3260596_3261292_-	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family	NA|294aa|down_9|NZ_CP020819.1_3261567_3262449_-	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	7	4108897-4109022	7	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GGGGGGCAGCAAGCTGGCGCAGCGAGCGCAGCGTGGGGGCATTTTC	46	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|245aa|up_9|NZ_CP020819.1_4095571_4096306_+	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional	NA|350aa|up_8|NZ_CP020819.1_4096346_4097396_+	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase	NA|193aa|up_7|NZ_CP020819.1_4097543_4098122_-	TIGR01841, hypothetical_protein, phasin family protein	NA|326aa|up_6|NZ_CP020819.1_4098508_4099486_+	cd13576, PBP2_BugD_Asp, Aspartic acid transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold	NA|1465aa|up_5|NZ_CP020819.1_4099579_4103974_-	pfam05785, CNF1, Rho-activating domain of cytotoxic necrotizing factor	NA|283aa|up_4|NZ_CP020819.1_4104174_4105023_-	COG1414, IclR, Transcriptional regulator [Transcription]	NA|271aa|up_3|NZ_CP020819.1_4105181_4105994_-	COG1058, CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]	NA|267aa|up_2|NZ_CP020819.1_4106048_4106849_-	pfam07264, EI24, Etoposide-induced protein 2	NA|128aa|up_1|NZ_CP020819.1_4106910_4107294_+	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains	NA|478aa|up_0|NZ_CP020819.1_4107305_4108739_-	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]	NA|110aa|down_0|NZ_CP020819.1_4109026_4109356_-	COG4392, COG4392, Predicted membrane protein [Function unknown]	NA|223aa|down_1|NZ_CP020819.1_4109358_4110027_-	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]	NA|307aa|down_2|NZ_CP020819.1_4110290_4111211_+	PRK06606, PRK06606, branched-chain amino acid transaminase	NA|71aa|down_3|NZ_CP020819.1_4111257_4111470_+	COG4391, COG4391, Uncharacterized protein conserved in bacteria [Function unknown]	NA|141aa|down_4|NZ_CP020819.1_4111492_4111915_+	pfam13474, SnoaL_3, SnoaL-like domain	NA|367aa|down_5|NZ_CP020819.1_4111931_4113032_+	COG0429, COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]	NA|506aa|down_6|NZ_CP020819.1_4113128_4114646_-	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only]	NA|280aa|down_7|NZ_CP020819.1_4114721_4115561_+	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]	NA|294aa|down_8|NZ_CP020819.1_4115582_4116464_-	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	NA|365aa|down_9|NZ_CP020819.1_4116545_4117640_-	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	8	4397923-4398016	8	CRISPRCasFinder	no	DEDDh	csa3,DEDDh,DinG,cas3	Unclear	GTGCCTGTCCCCGCCGGGACAGGCAC	26	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|398aa|up_9|NZ_CP020819.1_4386343_4387537_-	PRK06954, PRK06954, acetyl-CoA C-acetyltransferase	NA|343aa|up_8|NZ_CP020819.1_4387602_4388631_-	pfam00441, Acyl-CoA_dh_1, Acyl-CoA dehydrogenase, C-terminal domain	NA|391aa|up_7|NZ_CP020819.1_4388657_4389830_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|326aa|up_6|NZ_CP020819.1_4389955_4390933_+	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold	NA|324aa|up_5|NZ_CP020819.1_4390943_4391915_-	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold	NA|262aa|up_4|NZ_CP020819.1_4391981_4392767_-	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein	NA|411aa|up_3|NZ_CP020819.1_4392759_4393992_-	pfam02515, CoA_transf_3, CoA-transferase family III	NA|252aa|up_2|NZ_CP020819.1_4394187_4394943_-	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]	NA|173aa|up_1|NZ_CP020819.1_4395053_4395572_+	COG1285, SapB, Uncharacterized membrane protein [Function unknown]	NA|708aa|up_0|NZ_CP020819.1_4395568_4397692_-	PRK00007, PRK00007, elongation factor G; Reviewed	NA|157aa|down_0|NZ_CP020819.1_4398102_4398573_-	pfam00582, Usp, Universal stress protein family	NA|115aa|down_1|NZ_CP020819.1_4398661_4399006_-	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|467aa|down_2|NZ_CP020819.1_4399105_4400506_-	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]	NA|305aa|down_3|NZ_CP020819.1_4400694_4401609_+	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]	NA|220aa|down_4|NZ_CP020819.1_4401605_4402265_+	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism]	NA|308aa|down_5|NZ_CP020819.1_4402354_4403278_+	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|152aa|down_6|NZ_CP020819.1_4403283_4403739_-	COG4125, COG4125, Predicted membrane protein [Function unknown]	NA|368aa|down_7|NZ_CP020819.1_4403735_4404839_-	cd10807, YdjC_like_3, uncharacterized YdjC-like family proteins from bacteria	NA|91aa|down_8|NZ_CP020819.1_4404794_4405067_+	pfam04138, GtrA, GtrA-like protein	NA|540aa|down_9|NZ_CP020819.1_4405026_4406646_-	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	9	4533483-4533563	9	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GTGCCTGTCCCCGCCGGGACAGGC	24	1	1	4533507-4533539	NZ_CP020819.1_3963672-3963640	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA|42aa|up_2|NZ_CP020819.1_4531834_4531960_-,NA	NA|1169aa|up_9|NZ_CP020819.1_4519560_4523067_+	PRK13030, PRK13030, indolepyruvate ferredoxin oxidoreductase family protein	NA|976aa|up_8|NZ_CP020819.1_4523372_4526300_+	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha	NA|401aa|up_7|NZ_CP020819.1_4526321_4527524_+	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated	NA|221aa|up_6|NZ_CP020819.1_4527841_4528504_+	PRK14900, valS, valyl-tRNA synthetase; Provisional	NA|192aa|up_5|NZ_CP020819.1_4528642_4529218_+	pfam02325, YGGT, YGGT family	NA|488aa|up_4|NZ_CP020819.1_4529225_4530689_-	cd05945, DltA, D-alanine:D-alanyl carrier protein ligase (DltA) and similar proteins	NA|376aa|up_3|NZ_CP020819.1_4530699_4531827_-	TIGR04091, hypothetical_protein, D-alanyl-lipoteichoic acid biosynthesis protein DltB	NA|42aa|up_2|NZ_CP020819.1_4531834_4531960_-	NA	NA|376aa|up_1|NZ_CP020819.1_4531956_4533084_-	pfam04914, DltD, DltD protein	NA|80aa|up_0|NZ_CP020819.1_4533109_4533349_-	COG0236, AcpP, Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]	NA|168aa|down_0|NZ_CP020819.1_4533667_4534171_-	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]	NA|314aa|down_1|NZ_CP020819.1_4534344_4535286_-	cd01942, ribokinase_group_A, Ribokinase-like subgroup A	NA|376aa|down_2|NZ_CP020819.1_4535297_4536425_-	pfam11906, DUF3426, Protein of unknown function (DUF3426)	NA|308aa|down_3|NZ_CP020819.1_4536450_4537374_-	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA)	NA|449aa|down_4|NZ_CP020819.1_4537392_4538739_-	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated	NA|150aa|down_5|NZ_CP020819.1_4538748_4539198_-	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein	NA|145aa|down_6|NZ_CP020819.1_4539287_4539722_-	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase	NA|183aa|down_7|NZ_CP020819.1_4539800_4540349_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|457aa|down_8|NZ_CP020819.1_4540431_4541802_+	TIGR01081, mpl, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase	NA|198aa|down_9|NZ_CP020819.1_4541812_4542406_+	COG3150, COG3150, Predicted esterase [General function prediction only]
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	10	4676571-4676654	10	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GGTGCCTGTCCCCGCGGGGACAG	23	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA,NA	NA|429aa|up_9|NZ_CP020819.1_4668577_4669864_-	pfam00034, Cytochrom_C, Cytochrome c	NA|251aa|up_8|NZ_CP020819.1_4669874_4670627_-	COG2863, COG2863, Cytochrome c553 [Energy production and conversion]	NA|291aa|up_7|NZ_CP020819.1_4670798_4671671_+	PRK05416, PRK05416, RNase adapter RapZ	NA|317aa|up_6|NZ_CP020819.1_4671667_4672618_+	COG0797, RlpA, Lipoproteins [Cell envelope biogenesis, outer membrane]	NA|191aa|up_5|NZ_CP020819.1_4672614_4673187_-	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]	NA|313aa|up_4|NZ_CP020819.1_4673183_4674122_-	COG0313, COG0313, Predicted methyltransferases [General function prediction only]	NA|178aa|up_3|NZ_CP020819.1_4674188_4674722_+	PRK14685, PRK14685, hypothetical protein; Provisional	NA|201aa|up_2|NZ_CP020819.1_4674721_4675324_+	PRK13936, PRK13936, phosphoheptose isomerase; Provisional	NA|248aa|up_1|NZ_CP020819.1_4675320_4676064_+	PRK11023, PRK11023, divisome-associated lipoprotein YraP	NA|164aa|up_0|NZ_CP020819.1_4676060_4676552_+	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|263aa|down_0|NZ_CP020819.1_4676708_4677497_-	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]	NA|301aa|down_1|NZ_CP020819.1_4677758_4678661_+	PRK00942, PRK00942, acetylglutamate kinase; Provisional	NA|249aa|down_2|NZ_CP020819.1_4678660_4679407_+	cd02604, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to Saccharomyces cerevisiae Phm8p and Sdt1p	NA|192aa|down_3|NZ_CP020819.1_4679456_4680032_+	PRK09480, slmA, division inhibitor protein; Provisional	NA|498aa|down_4|NZ_CP020819.1_4680244_4681738_+	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region	NA|352aa|down_5|NZ_CP020819.1_4681748_4682804_+	pfam02615, Ldh_2, Malate/L-lactate dehydrogenase	NA|379aa|down_6|NZ_CP020819.1_4682829_4683966_-	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA	NA|651aa|down_7|NZ_CP020819.1_4683962_4685915_-	TIGR03423, pbp2_mrdA, penicillin-binding protein 2	NA|188aa|down_8|NZ_CP020819.1_4685928_4686492_-	TIGR03426, shape_MreD, rod shape-determining protein MreD	NA|295aa|down_9|NZ_CP020819.1_4686478_4687363_-	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional
GCF_003184485.1_ASM318448v1	NZ_CP020819	Bordetella bronchiseptica strain D973 chromosome, complete genome	11	4759592-4759672	11	CRISPRCasFinder	no		csa3,DEDDh,DinG,cas3	Orphan	GTGCCTGTCCCCGCGGGGACAGGCACCT	28	0	0	NA	NA	NA	1	1	Orphan	csa3,DEDDh,DinG,cas3	NA|79aa|up_8|NZ_CP020819.1_4750270_4750507_+,NA	NA|287aa|up_9|NZ_CP020819.1_4749282_4750143_+	cd01171, YXKO-related, B	NA|79aa|up_8|NZ_CP020819.1_4750270_4750507_+	NA	NA|543aa|up_7|NZ_CP020819.1_4750803_4752432_+	cd08498, PBP2_NikA_DppA_OppA_like_2, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|348aa|up_6|NZ_CP020819.1_4752480_4753524_+	cd06910, M14_ASTE_ASPA-like, Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup	NA|326aa|up_5|NZ_CP020819.1_4753582_4754560_+	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|307aa|up_4|NZ_CP020819.1_4754567_4755488_+	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|328aa|up_3|NZ_CP020819.1_4755484_4756468_+	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|337aa|up_2|NZ_CP020819.1_4756464_4757475_+	COG4608, AppF, ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]	NA|302aa|up_1|NZ_CP020819.1_4757477_4758383_+	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]	NA|378aa|up_0|NZ_CP020819.1_4758426_4759560_+	cd03885, M20_CPDG2, M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme	NA|690aa|down_0|NZ_CP020819.1_4759691_4761761_-	TIGR01074, ATP-dependent_DNA_helicase_Rep, ATP-dependent DNA helicase Rep	NA|701aa|down_1|NZ_CP020819.1_4761803_4763906_-	PRK05580, PRK05580, primosome assembly protein PriA; Validated	NA|359aa|down_2|NZ_CP020819.1_4764212_4765289_-	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated	NA|294aa|down_3|NZ_CP020819.1_4765364_4766246_-	PRK15115, PRK15115, response regulator GlrR; Provisional	NA|141aa|down_4|NZ_CP020819.1_4766428_4766851_-	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated	NA|467aa|down_5|NZ_CP020819.1_4766860_4768261_-	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated	NA|302aa|down_6|NZ_CP020819.1_4768303_4769209_-	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated	NA|514aa|down_7|NZ_CP020819.1_4769307_4770849_-	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated	NA|180aa|down_8|NZ_CP020819.1_4770883_4771423_-	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated	NA|157aa|down_9|NZ_CP020819.1_4771435_4771906_-	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated
