assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	1	595442-596589	1,1,1	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Type III-C,Type III-D,Type III-B,Type III-A	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	14,14,15	15	TypeIII-C,TypeIII-D,TypeIII-B,TypeIII-A	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|85aa|up_8|NZ_CP019613.1_588721_588976_-,NA|135aa|up_7|NZ_CP019613.1_589123_589528_+,NA|64aa|up_6|NZ_CP019613.1_589524_589716_+,NA|86aa|up_4|NZ_CP019613.1_591302_591560_+,NA|104aa|up_3|NZ_CP019613.1_591664_591976_+,NA|203aa|up_2|NZ_CP019613.1_592395_593004_+,NA	NA|92aa|up_9|NZ_CP019613.1_588270_588546_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP019613.1_588721_588976_-	NA	NA|135aa|up_7|NZ_CP019613.1_589123_589528_+	NA	NA|64aa|up_6|NZ_CP019613.1_589524_589716_+	NA	NA|385aa|up_5|NZ_CP019613.1_589914_591069_+	pfam00665, rve, Integrase core domain	NA|86aa|up_4|NZ_CP019613.1_591302_591560_+	NA	NA|104aa|up_3|NZ_CP019613.1_591664_591976_+	NA	NA|203aa|up_2|NZ_CP019613.1_592395_593004_+	NA	NA|470aa|up_1|NZ_CP019613.1_593074_594484_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP019613.1_594480_595293_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP019613.1_596620_597882_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	csm3gr7|237aa|down_1|NZ_CP019613.1_598245_598956_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_2|NZ_CP019613.1_598965_599340_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_3|NZ_CP019613.1_599336_601775_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|241aa|down_4|NZ_CP019613.1_601771_602494_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_5|NZ_CP019613.1_602893_603439_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|295aa|down_6|NZ_CP019613.1_603710_604595_-	COG2253, COG2253, Uncharacterized conserved protein [Function unknown]	NA|296aa|down_7|NZ_CP019613.1_604597_605485_-	pfam09407, AbiEi_1, AbiEi antitoxin C-terminal domain	NA|182aa|down_8|NZ_CP019613.1_605789_606335_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]	NA|90aa|down_9|NZ_CP019613.1_606331_606601_-	COG5552, COG5552, Uncharacterized conserved protein [Function unknown]
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	2	1136553-1136671	2	CRISPRCasFinder	no	cas3	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Unclear	GCCCCTGTGAGTCGAGTGAGCGGAACGAAC	30	1	1	1136583-1136641	NZ_CP019613.1_1136646-1136704	NA	1	1	Unclear	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA|138aa|down_6|NZ_CP019613.1_1142304_1142718_-,NA|126aa|down_7|NZ_CP019613.1_1142752_1143130_-	NA|719aa|up_9|NZ_CP019613.1_1123379_1125536_+	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism]	NA|223aa|up_8|NZ_CP019613.1_1125532_1126201_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|395aa|up_7|NZ_CP019613.1_1126301_1127486_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|765aa|up_6|NZ_CP019613.1_1127490_1129785_+	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]	NA|390aa|up_5|NZ_CP019613.1_1129773_1130943_-	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases	NA|175aa|up_4|NZ_CP019613.1_1130967_1131492_-	PLN02948, PLN02948, phosphoribosylaminoimidazole carboxylase	NA|430aa|up_3|NZ_CP019613.1_1131488_1132778_-	TIGR01161, N5-carboxyaminoimidazole_ribonucleotide_synthase, phosphoribosylaminoimidazole carboxylase, PurK protein	NA|273aa|up_2|NZ_CP019613.1_1132731_1133550_+	COG2246, COG2246, Predicted membrane protein [Function unknown]	NA|173aa|up_1|NZ_CP019613.1_1133504_1134023_-	pfam03703, bPH_2, Bacterial PH domain	NA|267aa|up_0|NZ_CP019613.1_1134065_1134866_-	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]	NA|223aa|down_0|NZ_CP019613.1_1136937_1137606_+	PRK00148, PRK00148, Maf-like protein; Reviewed	NA|298aa|down_1|NZ_CP019613.1_1137646_1138540_+	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]	NA|144aa|down_2|NZ_CP019613.1_1138536_1138968_+	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]	NA|601aa|down_3|NZ_CP019613.1_1139075_1140878_+	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]	NA|262aa|down_4|NZ_CP019613.1_1140887_1141673_-	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed	NA|146aa|down_5|NZ_CP019613.1_1141669_1142107_-	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]	NA|138aa|down_6|NZ_CP019613.1_1142304_1142718_-	NA	NA|126aa|down_7|NZ_CP019613.1_1142752_1143130_-	NA	NA|450aa|down_8|NZ_CP019613.1_1143163_1144513_-	PRK08297, PRK08297, L-lysine aminotransferase; Provisional	NA|151aa|down_9|NZ_CP019613.1_1144563_1145016_-	smart00344, HTH_ASNC, helix_turn_helix ASNC type
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	3	1213827-1214403	2	CRT	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	GCCGCCGTTGCCNCCGNNGCCGCCG	25	0	0	NA	NA	NA	7	7	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA|96aa|down_4|NZ_CP019613.1_1228635_1228923_-,NA|87aa|down_8|NZ_CP019613.1_1242042_1242303_-	NA|147aa|up_9|NZ_CP019613.1_1194508_1194949_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_8|NZ_CP019613.1_1194982_1195852_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_7|NZ_CP019613.1_1195872_1196883_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|215aa|up_6|NZ_CP019613.1_1197155_1197800_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_5|NZ_CP019613.1_1197866_1199096_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_4|NZ_CP019613.1_1199378_1200728_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_3|NZ_CP019613.1_1200739_1201879_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_2|NZ_CP019613.1_1201875_1202607_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|2524aa|up_1|NZ_CP019613.1_1202615_1210187_-	pfam00823, PPE, PPE family	NA|327aa|up_0|NZ_CP019613.1_1210235_1211216_-	pfam09606, Med15, ARC105 or Med15 subunit of Mediator complex non-fungal	NA|86aa|down_0|NZ_CP019613.1_1216505_1216763_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|3158aa|down_1|NZ_CP019613.1_1217018_1226492_-	pfam00823, PPE, PPE family	NA|149aa|down_2|NZ_CP019613.1_1227117_1227564_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|247aa|down_3|NZ_CP019613.1_1227600_1228341_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_4|NZ_CP019613.1_1228635_1228923_-	NA	NA|265aa|down_5|NZ_CP019613.1_1240652_1241447_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_CP019613.1_1241528_1241900_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|73aa|down_7|NZ_CP019613.1_1241797_1242016_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_CP019613.1_1242042_1242303_-	NA	NA|130aa|down_9|NZ_CP019613.1_1242417_1242807_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	4	1323339-1323428	3	CRISPRCasFinder	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|77aa|up_7|NZ_CP019613.1_1315375_1315606_+,NA|121aa|up_6|NZ_CP019613.1_1315709_1316072_-,NA|73aa|up_2|NZ_CP019613.1_1321404_1321623_-,NA|121aa|down_0|NZ_CP019613.1_1324413_1324776_-,NA|52aa|down_2|NZ_CP019613.1_1326617_1326773_-,NA|52aa|down_3|NZ_CP019613.1_1326797_1326953_-,NA|238aa|down_6|NZ_CP019613.1_1330988_1331702_-	NA|169aa|up_9|NZ_CP019613.1_1313686_1314193_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_8|NZ_CP019613.1_1314189_1315416_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_7|NZ_CP019613.1_1315375_1315606_+	NA	NA|121aa|up_6|NZ_CP019613.1_1315709_1316072_-	NA	NA|177aa|up_5|NZ_CP019613.1_1317030_1317561_+	pfam00823, PPE, PPE family	NA|252aa|up_4|NZ_CP019613.1_1317878_1318634_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|421aa|up_3|NZ_CP019613.1_1318717_1319979_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|73aa|up_2|NZ_CP019613.1_1321404_1321623_-	NA	NA|100aa|up_1|NZ_CP019613.1_1322117_1322417_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_CP019613.1_1322502_1323045_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP019613.1_1324413_1324776_-	NA	NA|179aa|down_1|NZ_CP019613.1_1324938_1325475_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP019613.1_1326617_1326773_-	NA	NA|52aa|down_3|NZ_CP019613.1_1326797_1326953_-	NA	NA|461aa|down_4|NZ_CP019613.1_1328145_1329528_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_CP019613.1_1329565_1330987_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_CP019613.1_1330988_1331702_-	NA	NA|285aa|down_7|NZ_CP019613.1_1331712_1332567_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_CP019613.1_1332788_1334663_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_CP019613.1_1334684_1335161_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	5	1408707-1409642	3	CRT	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	GGCGGNNNCGGCGGCNCCGGCGGC	24	0	0	NA	NA	NA	12	12	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA|280aa|down_5|NZ_CP019613.1_1430127_1430967_+	NA|351aa|up_9|NZ_CP019613.1_1393417_1394470_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|401aa|up_8|NZ_CP019613.1_1394469_1395672_-	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|281aa|up_7|NZ_CP019613.1_1395691_1396534_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|255aa|up_6|NZ_CP019613.1_1396568_1397333_-	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|318aa|up_5|NZ_CP019613.1_1397558_1398512_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_4|NZ_CP019613.1_1398536_1398728_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_3|NZ_CP019613.1_1398942_1400145_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_2|NZ_CP019613.1_1400169_1401291_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_1|NZ_CP019613.1_1401361_1402870_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1396aa|up_0|NZ_CP019613.1_1403040_1407228_+	pfam00934, PE, PE family	NA|516aa|down_0|NZ_CP019613.1_1412802_1414350_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|down_1|NZ_CP019613.1_1414346_1415183_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|down_2|NZ_CP019613.1_1422185_1422842_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_3|NZ_CP019613.1_1427520_1429167_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_4|NZ_CP019613.1_1429240_1430032_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_5|NZ_CP019613.1_1430127_1430967_+	NA	NA|399aa|down_6|NZ_CP019613.1_1431021_1432218_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_7|NZ_CP019613.1_1432246_1432957_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_8|NZ_CP019613.1_1433021_1434065_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_9|NZ_CP019613.1_1434217_1435129_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	6	1425073-1426204	4	CRT	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CNNCGGCGGNACCGGCGGCNNNGGCGGNNCCGGCGGC	37	7	10	1425200-1425246|1425284-1425318|1425596-1425636|1425674-1425708|1425674-1425708|1425674-1425708|1425674-1425708|1425746-1425780|1425818-1425864|1425902-1425936	NZ_CP019613.1_1426379-1426425|NZ_CP019613.1_1426463-1426497|NZ_CP019613.1_1426205-1426245|NZ_CP019613.1_1424117-1424151|NZ_CP019613.1_1424429-1424463|NZ_CP019613.1_1424780-1424814|NZ_CP019613.1_1425065-1425099|NZ_CP019613.1_1426316-1426350|NZ_CP019613.1_1426388-1426434|NZ_CP019613.1_1426472-1426506	NA	14	14	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA|280aa|down_2|NZ_CP019613.1_1430127_1430967_+	NA|318aa|up_9|NZ_CP019613.1_1397558_1398512_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP019613.1_1398536_1398728_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP019613.1_1398942_1400145_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP019613.1_1400169_1401291_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP019613.1_1401361_1402870_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1396aa|up_4|NZ_CP019613.1_1403040_1407228_+	pfam00934, PE, PE family	NA|1706aa|up_3|NZ_CP019613.1_1407518_1412636_+	pfam00934, PE, PE family	NA|516aa|up_2|NZ_CP019613.1_1412802_1414350_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_1|NZ_CP019613.1_1414346_1415183_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|219aa|up_0|NZ_CP019613.1_1422185_1422842_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP019613.1_1427520_1429167_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|264aa|down_1|NZ_CP019613.1_1429240_1430032_+	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein	NA|280aa|down_2|NZ_CP019613.1_1430127_1430967_+	NA	NA|399aa|down_3|NZ_CP019613.1_1431021_1432218_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_4|NZ_CP019613.1_1432246_1432957_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_5|NZ_CP019613.1_1433021_1434065_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_6|NZ_CP019613.1_1434217_1435129_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_7|NZ_CP019613.1_1435144_1436209_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_8|NZ_CP019613.1_1436225_1437410_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_9|NZ_CP019613.1_1437451_1438483_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	7	1587604-1587692	4	CRISPRCasFinder	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|257aa|up_6|NZ_CP019613.1_1578190_1578961_-,NA|233aa|up_0|NZ_CP019613.1_1586708_1587407_-,NA|126aa|down_6|NZ_CP019613.1_1592927_1593305_+	NA|388aa|up_9|NZ_CP019613.1_1573861_1575025_-	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase	NA|351aa|up_8|NZ_CP019613.1_1575021_1576074_-	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein	NA|288aa|up_7|NZ_CP019613.1_1576572_1577436_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_6|NZ_CP019613.1_1578190_1578961_-	NA	NA|549aa|up_5|NZ_CP019613.1_1578957_1580604_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_4|NZ_CP019613.1_1580600_1581464_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_3|NZ_CP019613.1_1581456_1582383_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_2|NZ_CP019613.1_1582384_1584010_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|652aa|up_1|NZ_CP019613.1_1584717_1586673_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP019613.1_1586708_1587407_-	NA	NA|173aa|down_0|NZ_CP019613.1_1587752_1588271_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP019613.1_1588271_1589255_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP019613.1_1589247_1590441_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP019613.1_1590446_1591268_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP019613.1_1591399_1592083_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP019613.1_1592082_1592820_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP019613.1_1592927_1593305_+	NA	NA|225aa|down_7|NZ_CP019613.1_1593403_1594078_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP019613.1_1594183_1594978_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP019613.1_1594984_1595440_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	8	2221348-2221458	2	PILER-CR	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CCGCCGTTGCCGCCGTTGCCGATC	24	0	0	NA	NA	NA	2	2	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|61aa|up_0|NZ_CP019613.1_2219680_2219863_-,NA	NA|398aa|up_9|NZ_CP019613.1_2209858_2211052_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP019613.1_2211087_2212770_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP019613.1_2212786_2214982_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP019613.1_2215095_2216229_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP019613.1_2216225_2216846_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP019613.1_2216942_2217524_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP019613.1_2217453_2218179_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP019613.1_2218268_2219189_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP019613.1_2219228_2219657_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP019613.1_2219680_2219863_-	NA	NA|405aa|down_0|NZ_CP019613.1_2223028_2224243_-	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional	NA|903aa|down_1|NZ_CP019613.1_2225035_2227744_-	pfam00934, PE, PE family	NA|539aa|down_2|NZ_CP019613.1_2228034_2229651_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_3|NZ_CP019613.1_2229674_2230583_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_4|NZ_CP019613.1_2230806_2232702_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_5|NZ_CP019613.1_2232698_2234315_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_6|NZ_CP019613.1_2234311_2238304_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_7|NZ_CP019613.1_2238300_2238609_+	pfam00934, PE, PE family	NA|514aa|down_8|NZ_CP019613.1_2238611_2240153_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|98aa|down_9|NZ_CP019613.1_2240201_2240495_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	9	2255140-2255838	5	CRISPRCasFinder	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	33	2	2	2255428-2255469|2255503-2255535	NZ_CP019613.1_2263444-2263485|NZ_CP019613.1_2262259-2262291	NA	10	10	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|101aa|up_4|NZ_CP019613.1_2252152_2252455_+,NA|161aa|down_1|NZ_CP019613.1_2265233_2265716_-,NA|410aa|down_5|NZ_CP019613.1_2267832_2269062_+	NA|262aa|up_9|NZ_CP019613.1_2246847_2247633_+	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional	NA|268aa|up_8|NZ_CP019613.1_2247621_2248425_-	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown]	NA|466aa|up_7|NZ_CP019613.1_2248434_2249832_-	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase)	NA|592aa|up_6|NZ_CP019613.1_2250010_2251786_+	pfam00934, PE, PE family	NA|76aa|up_5|NZ_CP019613.1_2251928_2252156_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|101aa|up_4|NZ_CP019613.1_2252152_2252455_+	NA	NA|74aa|up_3|NZ_CP019613.1_2252502_2252724_+	PHA01748, PHA01748, hypothetical protein	NA|142aa|up_2|NZ_CP019613.1_2252720_2253146_+	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins	NA|211aa|up_1|NZ_CP019613.1_2253281_2253914_+	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|303aa|up_0|NZ_CP019613.1_2253910_2254819_+	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs	NA|224aa|down_0|NZ_CP019613.1_2264574_2265246_+	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase	NA|161aa|down_1|NZ_CP019613.1_2265233_2265716_-	NA	NA|239aa|down_2|NZ_CP019613.1_2265773_2266490_+	cd03392, PAP2_like_2, PAP2_like_2 proteins	NA|219aa|down_3|NZ_CP019613.1_2266591_2267248_+	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown]	NA|164aa|down_4|NZ_CP019613.1_2267317_2267809_-	pfam13577, SnoaL_4, SnoaL-like domain	NA|410aa|down_5|NZ_CP019613.1_2267832_2269062_+	NA	NA|621aa|down_6|NZ_CP019613.1_2269216_2271079_+	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones]	NA|129aa|down_7|NZ_CP019613.1_2271150_2271537_+	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]	NA|212aa|down_8|NZ_CP019613.1_2271539_2272175_-	pfam11259, DUF3060, Protein of unknown function (DUF3060)	NA|295aa|down_9|NZ_CP019613.1_2272262_2273147_+	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	10	2519945-2520082	5	CRT	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CCGCCGACCACGCCGGTG	18	2	3	2519963-2519980|2519963-2519980|2520047-2520064	NZ_CP019613.1_1911991-1912008|NZ_CP019613.1_3300731-3300748|NZ_CP019613.1_2860548-2860565	NA	3	3	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|54aa|up_7|NZ_CP019613.1_2510690_2510852_-,NA|478aa|up_0|NZ_CP019613.1_2516960_2518394_-,NA|450aa|down_2|NZ_CP019613.1_2521717_2523067_-,NA|93aa|down_5|NZ_CP019613.1_2524597_2524876_-	NA|325aa|up_9|NZ_CP019613.1_2508460_2509435_+	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB	NA|406aa|up_8|NZ_CP019613.1_2509476_2510694_+	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]	NA|54aa|up_7|NZ_CP019613.1_2510690_2510852_-	NA	NA|106aa|up_6|NZ_CP019613.1_2510898_2511216_+	pfam14012, DUF4229, Protein of unknown function (DUF4229)	NA|626aa|up_5|NZ_CP019613.1_2511362_2513240_+	pfam00934, PE, PE family	NA|336aa|up_4|NZ_CP019613.1_2513135_2514143_-	TIGR00747, 3-oxoacyl-_synthase_3, 3-oxoacyl-(acyl-carrier-protein) synthase III	NA|293aa|up_3|NZ_CP019613.1_2514224_2515103_-	TIGR00751, 14-dihydroxy-2-naphthoate_octaprenyltransferase, 1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA|265aa|up_2|NZ_CP019613.1_2515119_2515914_+	PRK07823, PRK07823, S-methyl-5'-thioadenosine phosphorylase	NA|347aa|up_1|NZ_CP019613.1_2515910_2516951_+	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs	NA|478aa|up_0|NZ_CP019613.1_2516960_2518394_-	NA	NA|211aa|down_0|NZ_CP019613.1_2520405_2521038_+	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily	NA|221aa|down_1|NZ_CP019613.1_2521034_2521697_+	COG3222, COG3222, Uncharacterized protein conserved in bacteria [Function unknown]	NA|450aa|down_2|NZ_CP019613.1_2521717_2523067_-	NA	NA|381aa|down_3|NZ_CP019613.1_2523078_2524221_-	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase	NA|101aa|down_4|NZ_CP019613.1_2524235_2524538_-	pfam11829, DUF3349, Protein of unknown function (DUF3349)	NA|93aa|down_5|NZ_CP019613.1_2524597_2524876_-	NA	NA|418aa|down_6|NZ_CP019613.1_2524872_2526126_-	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism]	NA|129aa|down_7|NZ_CP019613.1_2526245_2526632_-	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family	NA|295aa|down_8|NZ_CP019613.1_2526694_2527579_-	PRK05866, PRK05866, SDR family oxidoreductase	NA|301aa|down_9|NZ_CP019613.1_2527674_2528577_-	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	11	2580679-2580755	6	CRISPRCasFinder	no	c2c9_V-U4	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA	NA|72aa|up_9|NZ_CP019613.1_2566363_2566579_+	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|136aa|up_8|NZ_CP019613.1_2566575_2566983_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_7|NZ_CP019613.1_2567042_2567729_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|796aa|up_6|NZ_CP019613.1_2570537_2572925_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP019613.1_2573062_2573785_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP019613.1_2573781_2574579_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP019613.1_2574580_2575468_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP019613.1_2575473_2576688_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NZ_CP019613.1_2576684_2577716_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NZ_CP019613.1_2577712_2579158_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP019613.1_2581890_2583441_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP019613.1_2583492_2583885_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP019613.1_2583881_2584139_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP019613.1_2584321_2585557_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP019613.1_2585807_2586221_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP019613.1_2586217_2586454_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP019613.1_2586557_2587064_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP019613.1_2587177_2587648_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP019613.1_2587691_2588453_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP019613.1_2588509_2588821_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	12	2812561-2813508	6	CRT	no	csa3	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	2813344-2813379|2813344-2813379|2813344-2813379	NZ_CP019613.1_2563782-2563747|NZ_CP019613.1_3102578-3102613|NZ_CP019613.1_4311432-4311397	NA	19	19	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA,NA|184aa|down_2|NZ_CP019613.1_2817518_2818070_-,NA|81aa|down_8|NZ_CP019613.1_2824891_2825134_+	NA|214aa|up_9|NZ_CP019613.1_2799500_2800142_-	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU	NA|685aa|up_8|NZ_CP019613.1_2800199_2802254_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|389aa|up_7|NZ_CP019613.1_2802419_2803586_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_6|NZ_CP019613.1_2803673_2804690_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|214aa|up_5|NZ_CP019613.1_2804851_2805493_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_4|NZ_CP019613.1_2805573_2806629_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_3|NZ_CP019613.1_2806680_2807073_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_2|NZ_CP019613.1_2807130_2807553_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|302aa|up_1|NZ_CP019613.1_2807910_2808816_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP019613.1_2808834_2809650_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|883aa|down_0|NZ_CP019613.1_2813777_2816426_-	pfam00934, PE, PE family	NA|215aa|down_1|NZ_CP019613.1_2816893_2817538_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_2|NZ_CP019613.1_2817518_2818070_-	NA	NA|241aa|down_3|NZ_CP019613.1_2818150_2818873_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_4|NZ_CP019613.1_2818943_2819972_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_5|NZ_CP019613.1_2820660_2821431_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_6|NZ_CP019613.1_2821517_2822330_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|421aa|down_7|NZ_CP019613.1_2823109_2824371_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|81aa|down_8|NZ_CP019613.1_2824891_2825134_+	NA	NA|431aa|down_9|NZ_CP019613.1_2825410_2826703_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	13	2851880-2852131	3	PILER-CR	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CGGGTGGTGCCAGGTCGGCGGGCGCGGGTGGCGCCAGTTCGGCGGGCGCGGGTGGCGCCAGGT	63	1	1	2852053-2852108	NZ_CP019613.1_2852181-2852236	NA	2	2	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|67aa|up_3|NZ_CP019613.1_2849978_2850179_+,NA	NA|158aa|up_9|NZ_CP019613.1_2840555_2841029_+	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|398aa|up_8|NZ_CP019613.1_2841025_2842219_-	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC	NA|404aa|up_7|NZ_CP019613.1_2842375_2843587_+	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase	NA|721aa|up_6|NZ_CP019613.1_2843591_2845754_+	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB	NA|543aa|up_5|NZ_CP019613.1_2845821_2847450_-	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|757aa|up_4|NZ_CP019613.1_2847640_2849911_-	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain	NA|67aa|up_3|NZ_CP019613.1_2849978_2850179_+	NA	NA|168aa|up_2|NZ_CP019613.1_2850188_2850692_+	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC	NA|161aa|up_1|NZ_CP019613.1_2850688_2851171_+	cd00886, MogA_MoaB, MogA_MoaB family	NA|142aa|up_0|NZ_CP019613.1_2851167_2851593_+	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism]	NA|93aa|down_0|NZ_CP019613.1_2853281_2853560_-	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins	NA|361aa|down_1|NZ_CP019613.1_2853563_2854646_-	PRK00164, moaA, GTP 3',8-cyclase MoaA	NA|130aa|down_2|NZ_CP019613.1_2854642_2855032_-	PRK11770, PRK11770, YccF domain-containing protein	NA|136aa|down_3|NZ_CP019613.1_2855196_2855604_+	COG1278, CspC, Cold shock proteins [Transcription]	NA|610aa|down_4|NZ_CP019613.1_2855722_2857552_-	pfam00934, PE, PE family	NA|651aa|down_5|NZ_CP019613.1_2857812_2859765_+	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|387aa|down_6|NZ_CP019613.1_2859853_2861014_-	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|163aa|down_7|NZ_CP019613.1_2861113_2861602_-	pfam10969, DUF2771, Protein of unknown function (DUF2771)	NA|549aa|down_8|NZ_CP019613.1_2861598_2863245_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|263aa|down_9|NZ_CP019613.1_2863382_2864171_+	pfam11228, DUF3027, Protein of unknown function (DUF3027)
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	14	3462430-3463502	7	CRISPRCasFinder	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	3462630-3462651	NZ_CP019613.1_3100904-3100883	NA	15	15	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|191aa|up_7|NZ_CP019613.1_3453938_3454511_+,NA	NA|103aa|up_9|NZ_CP019613.1_3451708_3452017_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP019613.1_3452013_3453633_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|191aa|up_7|NZ_CP019613.1_3453938_3454511_+	NA	NA|209aa|up_6|NZ_CP019613.1_3454645_3455272_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP019613.1_3455337_3455670_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP019613.1_3455685_3456942_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP019613.1_3457069_3458281_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP019613.1_3458353_3459832_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP019613.1_3459828_3461214_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP019613.1_3461291_3462326_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP019613.1_3464356_3464758_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP019613.1_3464754_3465012_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP019613.1_3465094_3466054_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP019613.1_3466078_3467041_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP019613.1_3467174_3467777_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP019613.1_3467857_3469825_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP019613.1_3469842_3470667_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP019613.1_3470835_3471318_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP019613.1_3471389_3472214_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP019613.1_3472410_3473349_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	15	3527115-3527340	4	PILER-CR	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	CGTTGGCGCCGTTGCCGCCGGCGCCGCCGTTGCCGCC	37	0	0	NA	NA	NA	2	2	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|38aa|up_8|NZ_CP019613.1_3513221_3513335_-,NA|137aa|up_7|NZ_CP019613.1_3513384_3513795_-,NA|288aa|down_2|NZ_CP019613.1_3531167_3532031_+	NA|162aa|up_9|NZ_CP019613.1_3512304_3512790_-	cd07820, SRPBCC_3, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|38aa|up_8|NZ_CP019613.1_3513221_3513335_-	NA	NA|137aa|up_7|NZ_CP019613.1_3513384_3513795_-	NA	NA|248aa|up_6|NZ_CP019613.1_3513811_3514555_-	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	NA|305aa|up_5|NZ_CP019613.1_3514551_3515466_-	TIGR00534, Putative_OxPP_cycle_protein_OpcA, glucose-6-phosphate dehydrogenase assembly protein OpcA	NA|515aa|up_4|NZ_CP019613.1_3515518_3517063_-	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated	NA|374aa|up_3|NZ_CP019613.1_3517059_3518181_-	PRK03343, PRK03343, transaldolase; Validated	NA|701aa|up_2|NZ_CP019613.1_3518197_3520300_-	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism]	NA|1399aa|up_1|NZ_CP019613.1_3520738_3524935_-	pfam00934, PE, PE family	NA|309aa|up_0|NZ_CP019613.1_3525336_3526263_+	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional	NA|422aa|down_0|NZ_CP019613.1_3528868_3530134_+	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]	NA|329aa|down_1|NZ_CP019613.1_3530161_3531148_-	cd05286, QOR2, Quinone oxidoreductase (QOR)	NA|288aa|down_2|NZ_CP019613.1_3531167_3532031_+	NA	NA|311aa|down_3|NZ_CP019613.1_3531980_3532913_-	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]	NA|262aa|down_4|NZ_CP019613.1_3533024_3533810_-	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family	NA|314aa|down_5|NZ_CP019613.1_3533806_3534748_-	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms]	NA|592aa|down_6|NZ_CP019613.1_3534903_3536679_-	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein	NA|269aa|down_7|NZ_CP019613.1_3536726_3537533_+	COG2345, COG2345, Predicted transcriptional regulator [Transcription]	NA|847aa|down_8|NZ_CP019613.1_3537529_3540070_+	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB	NA|398aa|down_9|NZ_CP019613.1_3540066_3541260_+	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	16	3960848-3961102	7	CRT	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	3960929-3960946|3960929-3960946|3961019-3961036	NZ_CP019613.1_2289740-2289723|NZ_CP019613.1_2496008-2495991|NZ_CP019613.1_922300-922283	NA	5	5	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|88aa|up_0|NZ_CP019613.1_3960207_3960471_-,NA	NA|165aa|up_9|NZ_CP019613.1_3946501_3946996_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP019613.1_3947399_3948077_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP019613.1_3948435_3951261_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP019613.1_3951487_3952348_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP019613.1_3952388_3953255_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP019613.1_3953259_3955146_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP019613.1_3955161_3957195_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP019613.1_3957314_3959540_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP019613.1_3959815_3960211_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP019613.1_3960207_3960471_-	NA	NA|346aa|down_0|NZ_CP019613.1_3962239_3963277_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP019613.1_3963276_3964644_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|480aa|down_2|NZ_CP019613.1_3964817_3966257_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP019613.1_3966289_3967741_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP019613.1_3967770_3968721_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP019613.1_3968735_3969152_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP019613.1_3969429_3969852_+	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria	NA|101aa|down_7|NZ_CP019613.1_3969900_3970203_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP019613.1_3970199_3970514_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP019613.1_3970513_3972247_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_003287185.1_ASM328718v1	NZ_CP019613	Mycobacterium tuberculosis strain H112 chromosome, complete genome	17	4043992-4044211	8	CRISPRCasFinder	no		csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,c2c9_V-U4,csm3gr7,csm2gr11,cas10,cas6,cas3,DEDDh,DinG,WYL,cas4	NA|136aa|up_2|NZ_CP019613.1_4032530_4032938_-,NA|127aa|down_5|NZ_CP019613.1_4051727_4052108_-	NA|155aa|up_9|NZ_CP019613.1_4025858_4026323_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_8|NZ_CP019613.1_4026498_4028721_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_7|NZ_CP019613.1_4028758_4029202_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_6|NZ_CP019613.1_4029315_4029909_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_5|NZ_CP019613.1_4029991_4030597_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|335aa|up_4|NZ_CP019613.1_4030696_4031701_-	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family	NA|251aa|up_3|NZ_CP019613.1_4031800_4032553_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP019613.1_4032530_4032938_-	NA	NA|767aa|up_1|NZ_CP019613.1_4033072_4035373_+	PLN02892, PLN02892, isocitrate lyase	NA|421aa|up_0|NZ_CP019613.1_4039568_4040830_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|155aa|down_0|NZ_CP019613.1_4046238_4046703_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP019613.1_4046800_4047664_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|424aa|down_2|NZ_CP019613.1_4047701_4048973_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP019613.1_4049244_4050360_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP019613.1_4050350_4051691_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP019613.1_4051727_4052108_-	NA	NA|621aa|down_6|NZ_CP019613.1_4052264_4054127_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP019613.1_4054134_4054614_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP019613.1_4054850_4055624_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP019613.1_4055627_4056395_-	PRK05867, PRK05867, SDR family oxidoreductase
