assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	1	794835-794979	1	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	GCGGAGTGGAGGCCGACGGTCAAACGGCTGCCCTTGCCGGGGG	43	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|76aa|up_8|NZ_CP044407.1_784250_784478_+,NA|79aa|down_8|NZ_CP044407.1_803940_804177_-	NA|134aa|up_9|NZ_CP044407.1_783493_783895_+	pfam13577, SnoaL_4, SnoaL-like domain	NA|76aa|up_8|NZ_CP044407.1_784250_784478_+	NA	NA|180aa|up_7|NZ_CP044407.1_784557_785097_-	pfam03413, PepSY, Peptidase propeptide and YPEB domain	NA|234aa|up_6|NZ_CP044407.1_785358_786060_+	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|475aa|up_5|NZ_CP044407.1_786072_787497_+	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|1178aa|up_4|NZ_CP044407.1_787730_791264_+	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed	NA|208aa|up_3|NZ_CP044407.1_791283_791907_-	TIGR04037, predicted_flavoprotein, LLM-partnered FMN reductase, CE1759 family	NA|362aa|up_2|NZ_CP044407.1_791903_792989_-	TIGR04036, family_protein, putative luciferase-like monooxygenase, FMN-dependent, CE1758 family	NA|306aa|up_1|NZ_CP044407.1_793060_793978_-	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|251aa|up_0|NZ_CP044407.1_794058_794811_+	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083	NA|231aa|down_0|NZ_CP044407.1_795065_795758_+	pfam14099, Polysacc_lyase, Polysaccharide lyase	NA|581aa|down_1|NZ_CP044407.1_795726_797469_-	PRK13800, PRK13800, fumarate reductase/succinate dehydrogenase flavoprotein subunit	NA|194aa|down_2|NZ_CP044407.1_797530_798112_-	pfam04264, YceI, YceI-like domain	NA|267aa|down_3|NZ_CP044407.1_798217_799018_+	cd00293, USP_Like, Usp: Universal stress protein family	NA|323aa|down_4|NZ_CP044407.1_799118_800087_+	pfam05257, CHAP, CHAP domain	NA|227aa|down_5|NZ_CP044407.1_800837_801518_-	pfam11361, DUF3159, Protein of unknown function (DUF3159)	NA|498aa|down_6|NZ_CP044407.1_801660_803154_-	pfam01861, DUF43, Protein of unknown function DUF43	NA|252aa|down_7|NZ_CP044407.1_803177_803933_-	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs	NA|79aa|down_8|NZ_CP044407.1_803940_804177_-	NA	NA|384aa|down_9|NZ_CP044407.1_804173_805325_-	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH)
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	2	2735068-2735168	2	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	GCGATGCAGCAATCGCACGCGAG	23	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|192aa|up_1|NZ_CP044407.1_2732960_2733536_-,NA	NA|298aa|up_9|NZ_CP044407.1_2722866_2723760_+	pfam14472, DUF4429, Domain of unknown function (DUF4429)	NA|341aa|up_8|NZ_CP044407.1_2723814_2724837_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|548aa|up_7|NZ_CP044407.1_2724937_2726581_+	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]	NA|260aa|up_6|NZ_CP044407.1_2726991_2727771_-	pfam02525, Flavodoxin_2, Flavodoxin-like fold	NA|329aa|up_5|NZ_CP044407.1_2728377_2729364_+	PRK09393, ftrA, transcriptional activator FtrA; Provisional	NA|112aa|up_4|NZ_CP044407.1_2729580_2729916_+	PRK12748, PRK12748, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|406aa|up_3|NZ_CP044407.1_2730030_2731248_+	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE)	NA|525aa|up_2|NZ_CP044407.1_2731290_2732865_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|192aa|up_1|NZ_CP044407.1_2732960_2733536_-	NA	NA|419aa|up_0|NZ_CP044407.1_2733535_2734792_-	PRK05476, PRK05476, S-adenosyl-L-homocysteine hydrolase; Provisional	NA|477aa|down_0|NZ_CP044407.1_2735217_2736648_-	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase	NA|114aa|down_1|NZ_CP044407.1_2736769_2737111_+	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators	NA|225aa|down_2|NZ_CP044407.1_2737112_2737787_-	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|530aa|down_3|NZ_CP044407.1_2737802_2739392_-	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|318aa|down_4|NZ_CP044407.1_2739919_2740873_-	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]	NA|358aa|down_5|NZ_CP044407.1_2740869_2741943_-	PRK08674, PRK08674, bifunctional phosphoglucose/phosphomannose isomerase; Validated	NA|61aa|down_6|NZ_CP044407.1_2742008_2742191_-	COG2835, COG2835, Uncharacterized conserved protein [Function unknown]	NA|452aa|down_7|NZ_CP044407.1_2742187_2743543_-	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed	NA|124aa|down_8|NZ_CP044407.1_2743801_2744173_-	pfam12005, DUF3499, Protein of unknown function (DUF3499)	NA|139aa|down_9|NZ_CP044407.1_2744386_2744803_+	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	3	2987910-2988132	3	CRISPRCasFinder	no	WYL	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Unclear	CGCGCCCGCGGCCCCGCGGGGCGGCGGC	28	0	0	NA	NA	NA	3	3	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA,NA	NA|134aa|up_9|NZ_CP044407.1_2971078_2971480_-	pfam05995, CDO_I, Cysteine dioxygenase type I	NA|208aa|up_8|NZ_CP044407.1_2972019_2972643_+	pfam05257, CHAP, CHAP domain	NA|164aa|up_7|NZ_CP044407.1_2973111_2973603_+	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]	NA|805aa|up_6|NZ_CP044407.1_2973599_2976014_+	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]	NA|286aa|up_5|NZ_CP044407.1_2976010_2976868_+	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]	NA|366aa|up_4|NZ_CP044407.1_2976950_2978048_+	cd07823, SRPBCC_5, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins	NA|242aa|up_3|NZ_CP044407.1_2978109_2978835_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|1228aa|up_2|NZ_CP044407.1_2978861_2982545_-	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	NA|1162aa|up_1|NZ_CP044407.1_2982566_2986052_-	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	NA|315aa|up_0|NZ_CP044407.1_2986221_2987166_-	cd08411, PBP2_OxyR, The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily	NA|241aa|down_0|NZ_CP044407.1_2988298_2989021_-	cd05362, THN_reductase-like_SDR_c, tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs	NA|467aa|down_1|NZ_CP044407.1_2989194_2990595_-	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins	NA|213aa|down_2|NZ_CP044407.1_2990803_2991442_+	PRK03624, PRK03624, putative acetyltransferase; Provisional	NA|253aa|down_3|NZ_CP044407.1_2991630_2992389_+	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs	NA|475aa|down_4|NZ_CP044407.1_2992409_2993834_-	cd16018, Enpp, Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin	NA|340aa|down_5|NZ_CP044407.1_2993845_2994865_+	pfam02515, CoA_transf_3, CoA-transferase family III	NA|959aa|down_6|NZ_CP044407.1_2994923_2997800_+	COG3899, COG3899, Predicted ATPase [General function prediction only]	NA|274aa|down_7|NZ_CP044407.1_2997844_2998666_-	pfam13489, Methyltransf_23, Methyltransferase domain	NA|657aa|down_8|NZ_CP044407.1_2998817_3000788_-	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase	NA|254aa|down_9|NZ_CP044407.1_3000958_3001720_+	COG1414, IclR, Transcriptional regulator [Transcription]
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	4	3668746-3668880	4	CRISPRCasFinder	no	WYL	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Unclear	GGGGGCCTTCCTTCAACGGGCGCTGCGTGCGATTGCTGCATCGCTCCGAC	50	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|91aa|up_6|NZ_CP044407.1_3660843_3661116_+,NA	NA|161aa|up_9|NZ_CP044407.1_3659613_3660096_-	pfam13671, AAA_33, AAA domain	NA|80aa|up_8|NZ_CP044407.1_3660120_3660360_-	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators	NA|85aa|up_7|NZ_CP044407.1_3660405_3660660_-	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators	NA|91aa|up_6|NZ_CP044407.1_3660843_3661116_+	NA	NA|577aa|up_5|NZ_CP044407.1_3661519_3663250_+	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter	WYL|210aa|up_4|NZ_CP044407.1_3663253_3663883_-	pfam13280, WYL, WYL domain	NA|398aa|up_3|NZ_CP044407.1_3664273_3665467_+	pfam06441, EHN, Epoxide hydrolase N-terminus	NA|274aa|up_2|NZ_CP044407.1_3665539_3666361_-	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|247aa|up_1|NZ_CP044407.1_3666485_3667226_-	pfam13714, PEP_mutase, Phosphoenolpyruvate phosphomutase	NA|343aa|up_0|NZ_CP044407.1_3667346_3668375_+	COG2382, Fes, Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]	NA|73aa|down_0|NZ_CP044407.1_3669127_3669346_+	pfam10041, DUF2277, Uncharacterized conserved protein (DUF2277)	NA|342aa|down_1|NZ_CP044407.1_3669400_3670426_-	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional	NA|107aa|down_2|NZ_CP044407.1_3670588_3670909_+	pfam04024, PspC, PspC domain	NA|423aa|down_3|NZ_CP044407.1_3670913_3672182_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|114aa|down_4|NZ_CP044407.1_3672288_3672630_-	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein	NA|565aa|down_5|NZ_CP044407.1_3672683_3674378_+	pfam00149, Metallophos, Calcineurin-like phosphoesterase	NA|103aa|down_6|NZ_CP044407.1_3676360_3676669_+	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated	NA|405aa|down_7|NZ_CP044407.1_3677073_3678288_-	cd07719, arylsulfatase_AtsA-like_MBL-fold, Pseudoalteromonas carrageenovora arylsulfatase AtsA and related proteins; MBL-fold metallo-hydrolase domain	NA|366aa|down_8|NZ_CP044407.1_3678348_3679446_-	PRK06847, PRK06847, hypothetical protein; Provisional	NA|309aa|down_9|NZ_CP044407.1_3680464_3681391_-	TIGR03213, Biphenyl-23-diol_12-dioxygenase_1, 2,3-dihydroxybiphenyl 1,2-dioxygenase
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	5	4339607-4339758	5	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	GACTCTTCCAGGAGATCGCGCTTTCACGCACTAAGCGCGTCGCTCTAG	48	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|114aa|up_9|NZ_CP044407.1_4323919_4324261_-,NA|234aa|up_5|NZ_CP044407.1_4328720_4329422_+,NA|216aa|up_4|NZ_CP044407.1_4329471_4330119_-,NA|354aa|up_3|NZ_CP044407.1_4330475_4331537_+,NA|189aa|up_0|NZ_CP044407.1_4338633_4339200_+,NA|1693aa|down_2|NZ_CP044407.1_4347087_4352166_-,NA|283aa|down_4|NZ_CP044407.1_4355194_4356043_-,NA|180aa|down_7|NZ_CP044407.1_4357108_4357648_-,NA|96aa|down_9|NZ_CP044407.1_4359064_4359352_-	NA|114aa|up_9|NZ_CP044407.1_4323919_4324261_-	NA	NA|540aa|up_8|NZ_CP044407.1_4324349_4325969_-	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters	NA|599aa|up_7|NZ_CP044407.1_4325647_4327444_-	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|329aa|up_6|NZ_CP044407.1_4327460_4328447_-	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins	NA|234aa|up_5|NZ_CP044407.1_4328720_4329422_+	NA	NA|216aa|up_4|NZ_CP044407.1_4329471_4330119_-	NA	NA|354aa|up_3|NZ_CP044407.1_4330475_4331537_+	NA	NA|310aa|up_2|NZ_CP044407.1_4333354_4334284_+	cd00221, Vsr, Very Short Patch Repair (Vsr) Endonuclease	NA|553aa|up_1|NZ_CP044407.1_4336918_4338577_+	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]	NA|189aa|up_0|NZ_CP044407.1_4338633_4339200_+	NA	NA|382aa|down_0|NZ_CP044407.1_4341405_4342551_+	pfam08878, DUF1837, Domain of unknown function (DUF1837)	NA|1166aa|down_1|NZ_CP044407.1_4342540_4346038_+	COG1204, COG1204, Superfamily II helicase [General function prediction only]	NA|1693aa|down_2|NZ_CP044407.1_4347087_4352166_-	NA	NA|1008aa|down_3|NZ_CP044407.1_4352190_4355214_-	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment	NA|283aa|down_4|NZ_CP044407.1_4355194_4356043_-	NA	NA|146aa|down_5|NZ_CP044407.1_4356368_4356806_-	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1	NA|84aa|down_6|NZ_CP044407.1_4356793_4357045_-	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1	NA|180aa|down_7|NZ_CP044407.1_4357108_4357648_-	NA	NA|272aa|down_8|NZ_CP044407.1_4358224_4359040_-	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons	NA|96aa|down_9|NZ_CP044407.1_4359064_4359352_-	NA
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	6	4721536-4721636	6	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	CGGGCCTTGCTGGTGCGATTGCTGC	25	1	1	4721561-4721611	NZ_CP044407.1_4721326-4721376	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|63aa|up_6|NZ_CP044407.1_4712576_4712765_-,NA|177aa|up_3|NZ_CP044407.1_4716839_4717370_-,NA|203aa|down_0|NZ_CP044407.1_4721916_4722525_+,NA|100aa|down_5|NZ_CP044407.1_4724969_4725269_+	NA|79aa|up_9|NZ_CP044407.1_4710906_4711143_+	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed	NA|149aa|up_8|NZ_CP044407.1_4711161_4711608_+	PRK00137, rplI, 50S ribosomal protein L9; Reviewed	NA|229aa|up_7|NZ_CP044407.1_4711877_4712564_+	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls	NA|63aa|up_6|NZ_CP044407.1_4712576_4712765_-	NA	NA|442aa|up_5|NZ_CP044407.1_4712869_4714195_-	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins	NA|727aa|up_4|NZ_CP044407.1_4714621_4716802_+	TIGR00665, DnaB, replicative DNA helicase	NA|177aa|up_3|NZ_CP044407.1_4716839_4717370_-	NA	NA|261aa|up_2|NZ_CP044407.1_4717993_4718776_+	PRK06523, PRK06523, short chain dehydrogenase; Provisional	NA|448aa|up_1|NZ_CP044407.1_4718828_4720172_-	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]	NA|265aa|up_0|NZ_CP044407.1_4720174_4720969_-	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein	NA|203aa|down_0|NZ_CP044407.1_4721916_4722525_+	NA	NA|74aa|down_1|NZ_CP044407.1_4722524_4722746_+	COG3655, COG3655, Predicted transcriptional regulator [Transcription]	NA|300aa|down_2|NZ_CP044407.1_4722742_4723642_-	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family	NA|168aa|down_3|NZ_CP044407.1_4723676_4724180_-	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]	NA|210aa|down_4|NZ_CP044407.1_4724340_4724970_+	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal	NA|100aa|down_5|NZ_CP044407.1_4724969_4725269_+	NA	NA|258aa|down_6|NZ_CP044407.1_4725279_4726053_-	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase	NA|291aa|down_7|NZ_CP044407.1_4726183_4727056_+	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain	NA|392aa|down_8|NZ_CP044407.1_4727000_4728176_-	COG2890, HemK, Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]	NA|129aa|down_9|NZ_CP044407.1_4728262_4728649_+	pfam10823, DUF2568, Protein of unknown function (DUF2568)
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	7	5916546-5916768	7	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	CGCTCCGGCCGAGGCCGAACGCATCGCCCGCTC	33	0	0	NA	NA	NA	2	2	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|132aa|up_0|NZ_CP044407.1_5915800_5916196_+,NA|313aa|down_1|NZ_CP044407.1_5918844_5919783_+	NA|465aa|up_9|NZ_CP044407.1_5902401_5903796_+	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]	NA|425aa|up_8|NZ_CP044407.1_5903786_5905061_-	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]	NA|194aa|up_7|NZ_CP044407.1_5906669_5907251_+	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]	NA|329aa|up_6|NZ_CP044407.1_5907253_5908240_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|140aa|up_5|NZ_CP044407.1_5908320_5908740_+	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds	NA|386aa|up_4|NZ_CP044407.1_5908786_5909944_-	cd06453, SufS_like, Cysteine desulfurase (SufS)-like	NA|628aa|up_3|NZ_CP044407.1_5910070_5911954_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|431aa|up_2|NZ_CP044407.1_5912224_5913517_-	sd00006, TPR, Tetratricopeptide repeat	NA|225aa|up_1|NZ_CP044407.1_5914804_5915479_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|132aa|up_0|NZ_CP044407.1_5915800_5916196_+	NA	NA|383aa|down_0|NZ_CP044407.1_5917637_5918786_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|313aa|down_1|NZ_CP044407.1_5918844_5919783_+	NA	NA|149aa|down_2|NZ_CP044407.1_5919795_5920242_+	cd06587, VOC, vicinal oxygen chelate (VOC) family	NA|579aa|down_3|NZ_CP044407.1_5920246_5921983_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|598aa|down_4|NZ_CP044407.1_5921979_5923773_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|616aa|down_5|NZ_CP044407.1_5924085_5925933_-	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|852aa|down_6|NZ_CP044407.1_5925929_5928485_-	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases	NA|941aa|down_7|NZ_CP044407.1_5929086_5931909_-	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|430aa|down_8|NZ_CP044407.1_5932112_5933402_+	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|280aa|down_9|NZ_CP044407.1_5933698_5934538_-	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	8	5916969-5917190	8	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	CGCTCCGGCCGAGGCCGAACGCATCGCCCGCTC	33	0	0	NA	NA	NA	2	2	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|132aa|up_0|NZ_CP044407.1_5915800_5916196_+,NA|313aa|down_1|NZ_CP044407.1_5918844_5919783_+	NA|465aa|up_9|NZ_CP044407.1_5902401_5903796_+	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]	NA|425aa|up_8|NZ_CP044407.1_5903786_5905061_-	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]	NA|194aa|up_7|NZ_CP044407.1_5906669_5907251_+	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]	NA|329aa|up_6|NZ_CP044407.1_5907253_5908240_+	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain	NA|140aa|up_5|NZ_CP044407.1_5908320_5908740_+	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds	NA|386aa|up_4|NZ_CP044407.1_5908786_5909944_-	cd06453, SufS_like, Cysteine desulfurase (SufS)-like	NA|628aa|up_3|NZ_CP044407.1_5910070_5911954_+	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|431aa|up_2|NZ_CP044407.1_5912224_5913517_-	sd00006, TPR, Tetratricopeptide repeat	NA|225aa|up_1|NZ_CP044407.1_5914804_5915479_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|132aa|up_0|NZ_CP044407.1_5915800_5916196_+	NA	NA|383aa|down_0|NZ_CP044407.1_5917637_5918786_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|313aa|down_1|NZ_CP044407.1_5918844_5919783_+	NA	NA|149aa|down_2|NZ_CP044407.1_5919795_5920242_+	cd06587, VOC, vicinal oxygen chelate (VOC) family	NA|579aa|down_3|NZ_CP044407.1_5920246_5921983_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|598aa|down_4|NZ_CP044407.1_5921979_5923773_-	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]	NA|616aa|down_5|NZ_CP044407.1_5924085_5925933_-	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]	NA|852aa|down_6|NZ_CP044407.1_5925929_5928485_-	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases	NA|941aa|down_7|NZ_CP044407.1_5929086_5931909_-	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon	NA|430aa|down_8|NZ_CP044407.1_5932112_5933402_+	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain	NA|280aa|down_9|NZ_CP044407.1_5933698_5934538_-	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	9	6630666-6630798	9	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	CGCCTCCCGCTCCGCCAGGGCTCCGCTCCAGGCGCCGGTCAG	42	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA,NA	NA|407aa|up_9|NZ_CP044407.1_6619882_6621103_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|344aa|up_8|NZ_CP044407.1_6621310_6622342_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|468aa|up_7|NZ_CP044407.1_6622519_6623923_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|62aa|up_6|NZ_CP044407.1_6623999_6624185_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|67aa|up_5|NZ_CP044407.1_6624216_6624417_-	pfam04149, DUF397, Domain of unknown function (DUF397)	NA|271aa|up_4|NZ_CP044407.1_6624413_6625226_-	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|141aa|up_3|NZ_CP044407.1_6625322_6625745_+	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains	NA|722aa|up_2|NZ_CP044407.1_6625874_6628040_-	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only]	NA|383aa|up_1|NZ_CP044407.1_6628200_6629349_+	PRK07811, PRK07811, cystathionine gamma-synthase; Provisional	NA|306aa|up_0|NZ_CP044407.1_6629676_6630594_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|158aa|down_0|NZ_CP044407.1_6631402_6631876_-	COG5500, COG5500, Predicted integral membrane protein [Function unknown]	NA|218aa|down_1|NZ_CP044407.1_6632001_6632655_+	pfam14246, TetR_C_7, AefR-like transcriptional repressor, C-terminal region	NA|679aa|down_2|NZ_CP044407.1_6632662_6634699_-	COG4867, COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain [General function prediction only]	NA|470aa|down_3|NZ_CP044407.1_6634724_6636134_-	COG1239, ChlI, Mg-chelatase subunit ChlI [Coenzyme metabolism]	NA|388aa|down_4|NZ_CP044407.1_6637288_6638452_+	COG4398, COG4398, Uncharacterized protein conserved in bacteria [Function unknown]	NA|321aa|down_5|NZ_CP044407.1_6638448_6639411_+	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]	NA|270aa|down_6|NZ_CP044407.1_6639565_6640375_+	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain	NA|292aa|down_7|NZ_CP044407.1_6640396_6641272_-	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form	NA|479aa|down_8|NZ_CP044407.1_6641268_6642705_-	pfam03559, Hexose_dehydrat, NDP-hexose 2,3-dehydratase	NA|320aa|down_9|NZ_CP044407.1_6642990_6643950_+	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only]
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	10	6972422-6972509	10	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	GTTGCCGCGCTCGTCGTACCGCGCC	25	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|194aa|up_8|NZ_CP044407.1_6959592_6960174_-,NA|160aa|up_0|NZ_CP044407.1_6969578_6970058_-,NA|182aa|down_2|NZ_CP044407.1_6974990_6975536_-,NA|216aa|down_6|NZ_CP044407.1_6978646_6979294_+	NA|489aa|up_9|NZ_CP044407.1_6958046_6959513_+	cd00433, Peptidase_M17, Cytosol aminopeptidase family, N-terminal and catalytic domains	NA|194aa|up_8|NZ_CP044407.1_6959592_6960174_-	NA	NA|201aa|up_7|NZ_CP044407.1_6960269_6960872_-	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only]	NA|386aa|up_6|NZ_CP044407.1_6962745_6963903_+	cd16327, RseB, RseB, a sensor in periplasmic stress	NA|625aa|up_5|NZ_CP044407.1_6964039_6965914_+	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family	NA|119aa|up_4|NZ_CP044407.1_6966016_6966373_+	PRK01371, PRK01371, Sec-independent protein translocase protein TatB	NA|380aa|up_3|NZ_CP044407.1_6966517_6967657_-	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase	NA|167aa|up_2|NZ_CP044407.1_6967718_6968219_-	pfam06210, DUF1003, Protein of unknown function (DUF1003)	NA|436aa|up_1|NZ_CP044407.1_6968215_6969523_-	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]	NA|160aa|up_0|NZ_CP044407.1_6969578_6970058_-	NA	NA|112aa|down_0|NZ_CP044407.1_6973625_6973961_+	PHA03247, PHA03247, large tegument protein UL36; Provisional	NA|306aa|down_1|NZ_CP044407.1_6974034_6974952_+	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family	NA|182aa|down_2|NZ_CP044407.1_6974990_6975536_-	NA	NA|314aa|down_3|NZ_CP044407.1_6975576_6976518_+	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism]	NA|516aa|down_4|NZ_CP044407.1_6976605_6978153_+	COG1266, COG1266, Predicted metal-dependent membrane protease [General function prediction only]	NA|130aa|down_5|NZ_CP044407.1_6978183_6978573_-	cd04673, Nudix_Hydrolase_15, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X	NA|216aa|down_6|NZ_CP044407.1_6978646_6979294_+	NA	NA|282aa|down_7|NZ_CP044407.1_6979335_6980181_+	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]	NA|236aa|down_8|NZ_CP044407.1_6980211_6980919_+	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain	NA|312aa|down_9|NZ_CP044407.1_6980968_6981904_+	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	11	7129694-7129825	11	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	GGCCTTCCTTCAACGGGCGCTGCGTGCGATTGCTGCATCGCTCCGAC	47	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|90aa|up_8|NZ_CP044407.1_7121209_7121479_-,NA|146aa|up_2|NZ_CP044407.1_7127869_7128307_+,NA	NA|332aa|up_9|NZ_CP044407.1_7120202_7121198_+	PRK06256, PRK06256, biotin synthase; Validated	NA|90aa|up_8|NZ_CP044407.1_7121209_7121479_-	NA	NA|237aa|up_7|NZ_CP044407.1_7121480_7122191_-	cd06260, DUF820, Domain of unknown function (DUF820)	NA|244aa|up_6|NZ_CP044407.1_7122278_7123010_-	COG2188, PhnF, Transcriptional regulators [Transcription]	NA|412aa|up_5|NZ_CP044407.1_7123122_7124358_-	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed	NA|90aa|up_4|NZ_CP044407.1_7126243_7126513_-	pfam02467, Whib, Transcription factor WhiB	NA|313aa|up_3|NZ_CP044407.1_7126810_7127749_-	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]	NA|146aa|up_2|NZ_CP044407.1_7127869_7128307_+	NA	NA|253aa|up_1|NZ_CP044407.1_7128344_7129103_-	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily	NA|143aa|up_0|NZ_CP044407.1_7129153_7129582_-	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional	NA|305aa|down_0|NZ_CP044407.1_7130322_7131237_-	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)	NA|254aa|down_1|NZ_CP044407.1_7131336_7132098_+	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH)	NA|342aa|down_2|NZ_CP044407.1_7132097_7133123_+	pfam14486, DUF4432, Domain of unknown function (DUF4432)	NA|263aa|down_3|NZ_CP044407.1_7133119_7133908_+	PRK06398, PRK06398, aldose dehydrogenase; Validated	NA|393aa|down_4|NZ_CP044407.1_7133965_7135144_+	pfam16396, DUF5005, Domain of unknown function (DUF5005)	NA|310aa|down_5|NZ_CP044407.1_7135228_7136158_+	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|235aa|down_6|NZ_CP044407.1_7136192_7136897_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|424aa|down_7|NZ_CP044407.1_7137033_7138305_+	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]	NA|323aa|down_8|NZ_CP044407.1_7138312_7139281_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|278aa|down_9|NZ_CP044407.1_7139277_7140111_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	12	7596724-7596995	12	CRISPRCasFinder	no	WYL	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Unclear	CGGCGCGGACGGCGCGGACGGCGTGG	26	1	21	7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969|7596951-7596969	NZ_CP044407.1_7596978-7596996|NZ_CP044407.1_1073667-1073649|NZ_CP044407.1_2260059-2260041|NZ_CP044407.1_2260068-2260050|NZ_CP044407.1_3588385-3588367|NZ_CP044407.1_3588394-3588376|NZ_CP044407.1_973232-973250|NZ_CP044407.1_2356496-2356514|NZ_CP044407.1_2617180-2617198|NZ_CP044407.1_3780581-3780599|NZ_CP044407.1_4441066-4441084|NZ_CP044407.1_7455966-7455984|NZ_CP044407.1_7596987-7597005|NZ_CP044407.1_7950613-7950631|NZ_CP044407.1_8168923-8168941|NZ_CP044407.1_1588749-1588731|NZ_CP044407.1_1732364-1732346|NZ_CP044407.1_2260077-2260059|NZ_CP044407.1_2312474-2312456|NZ_CP044407.1_3588367-3588349|NZ_CP044407.1_3893406-3893388	NA	4	4	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA|206aa|up_3|NZ_CP044407.1_7591852_7592470_+,NA|474aa|up_0|NZ_CP044407.1_7594939_7596361_-,NA|411aa|down_3|NZ_CP044407.1_7602466_7603699_-,NA|118aa|down_8|NZ_CP044407.1_7608252_7608606_+	NA|393aa|up_9|NZ_CP044407.1_7584809_7585988_+	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]	NA|373aa|up_8|NZ_CP044407.1_7586023_7587142_+	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold	NA|275aa|up_7|NZ_CP044407.1_7587351_7588176_+	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]	NA|268aa|up_6|NZ_CP044407.1_7588262_7589066_+	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]	NA|470aa|up_5|NZ_CP044407.1_7589079_7590489_+	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase	NA|168aa|up_4|NZ_CP044407.1_7591017_7591521_-	pfam03703, bPH_2, Bacterial PH domain	NA|206aa|up_3|NZ_CP044407.1_7591852_7592470_+	NA	NA|440aa|up_2|NZ_CP044407.1_7592444_7593764_-	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type	NA|323aa|up_1|NZ_CP044407.1_7593959_7594928_-	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold	NA|474aa|up_0|NZ_CP044407.1_7594939_7596361_-	NA	NA|449aa|down_0|NZ_CP044407.1_7597325_7598672_-	cd01461, vWA_interalpha_trypsin_inhibitor, vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin)	NA|387aa|down_1|NZ_CP044407.1_7598668_7599829_-	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms]	NA|812aa|down_2|NZ_CP044407.1_7599968_7602404_-	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat	NA|411aa|down_3|NZ_CP044407.1_7602466_7603699_-	NA	WYL|177aa|down_4|NZ_CP044407.1_7603864_7604395_+	COG2378, COG2378, Predicted transcriptional regulator [Transcription]	NA|220aa|down_5|NZ_CP044407.1_7604797_7605457_-	pfam13489, Methyltransf_23, Methyltransferase domain	NA|282aa|down_6|NZ_CP044407.1_7605493_7606339_+	COG1378, COG1378, Predicted transcriptional regulators [Transcription]	NA|536aa|down_7|NZ_CP044407.1_7606349_7607957_-	pfam07905, PucR, Purine catabolism regulatory protein-like family	NA|118aa|down_8|NZ_CP044407.1_7608252_7608606_+	NA	NA|422aa|down_9|NZ_CP044407.1_7609063_7610329_+	cd13588, PBP2_polyamine_1, The periplasmic-binding component of an uncharacterized ABC transporter involved in uptake of polyamines; contains the type 2 periplasmic binding fold
GCF_008824145.1_ASM882414v1	NZ_CP044407	Actinomadura sp. WMMB499 chromosome, complete genome	13	7794515-7794669	13	CRISPRCasFinder	no		WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	Orphan	CTGACCGACGACCGGAGCGGAGCGCTAGCGGAGTGGAGGTCGGCGGGCGGGCGG	54	0	0	NA	NA	NA	1	1	Orphan	WYL,cas4,csa3,DinG,c2c9_V-U4,cas3,DEDDh	NA,NA|85aa|down_8|NZ_CP044407.1_7804832_7805087_-	NA|379aa|up_9|NZ_CP044407.1_7781405_7782542_+	PRK14278, PRK14278, chaperone protein DnaJ; Provisional	NA|244aa|up_8|NZ_CP044407.1_7782659_7783391_+	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional	NA|239aa|up_7|NZ_CP044407.1_7783456_7784173_-	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau	NA|196aa|up_6|NZ_CP044407.1_7784169_7784757_-	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family	NA|115aa|up_5|NZ_CP044407.1_7785057_7785402_+	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides	NA|352aa|up_4|NZ_CP044407.1_7785598_7786654_+	pfam02562, PhoH, PhoH-like protein	NA|160aa|up_3|NZ_CP044407.1_7786650_7787130_+	PRK00016, PRK00016, metal-binding heat shock protein; Provisional	NA|439aa|up_2|NZ_CP044407.1_7787147_7788464_+	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|111aa|up_1|NZ_CP044407.1_7788494_7788827_-	PRK06848, PRK06848, cytidine deaminase	NA|713aa|up_0|NZ_CP044407.1_7788979_7791118_+	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only]	NA|312aa|down_0|NZ_CP044407.1_7794700_7795636_+	PRK00089, era, GTPase Era; Reviewed	NA|271aa|down_1|NZ_CP044407.1_7795626_7796439_-	pfam16481, DUF5058, Domain of unknown function (DUF5058)	NA|571aa|down_2|NZ_CP044407.1_7796848_7798561_+	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated	NA|347aa|down_3|NZ_CP044407.1_7798595_7799636_+	COG1609, PurR, Transcriptional regulators [Transcription]	NA|452aa|down_4|NZ_CP044407.1_7799820_7801176_+	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold	NA|312aa|down_5|NZ_CP044407.1_7801294_7802230_+	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]	NA|293aa|down_6|NZ_CP044407.1_7802236_7803115_+	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]	NA|532aa|down_7|NZ_CP044407.1_7803170_7804766_+	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins	NA|85aa|down_8|NZ_CP044407.1_7804832_7805087_-	NA	NA|350aa|down_9|NZ_CP044407.1_7805090_7806140_-	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease
