assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	1	592838-592987	1	CRISPRCasFinder	no		DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	54	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA|579aa|up_6|NZ_CP040309.1_584003_585740_+,NA|245aa|down_7|NZ_CP040309.1_602064_602799_+	NA|238aa|up_9|NZ_CP040309.1_581906_582620_-	PRK12742, PRK12742, SDR family oxidoreductase	NA|198aa|up_8|NZ_CP040309.1_582690_583284_+	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family	NA|151aa|up_7|NZ_CP040309.1_583428_583881_+	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]	NA|579aa|up_6|NZ_CP040309.1_584003_585740_+	NA	NA|335aa|up_5|NZ_CP040309.1_585796_586801_-	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional	NA|139aa|up_4|NZ_CP040309.1_586962_587379_+	PRK11191, PRK11191, ribonuclease E inhibitor RraB	NA|168aa|up_3|NZ_CP040309.1_587424_587928_-	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family	NA|399aa|up_2|NZ_CP040309.1_588120_589317_+	COG4269, COG4269, Predicted membrane protein [Function unknown]	NA|952aa|up_1|NZ_CP040309.1_589371_592227_-	PRK05729, valS, valyl-tRNA synthetase; Reviewed	NA|148aa|up_0|NZ_CP040309.1_592226_592670_-	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated	NA|504aa|down_0|NZ_CP040309.1_593023_594535_-	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional	NA|367aa|down_1|NZ_CP040309.1_594801_595902_+	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional	NA|361aa|down_2|NZ_CP040309.1_595901_596984_+	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional	NA|501aa|down_3|NZ_CP040309.1_597144_598647_-	pfam05872, DUF853, Bacterial protein of unknown function (DUF853)	NA|340aa|down_4|NZ_CP040309.1_598776_599796_-	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD)	NA|425aa|down_5|NZ_CP040309.1_600240_601515_+	PRK09692, PRK09692, integrase; Provisional	NA|102aa|down_6|NZ_CP040309.1_601682_601988_+	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins	NA|245aa|down_7|NZ_CP040309.1_602064_602799_+	NA	NA|415aa|down_8|NZ_CP040309.1_602836_604081_-	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair]	NA|191aa|down_9|NZ_CP040309.1_604406_604979_-	pfam07455, Psu, Phage polarity suppression protein (Psu)
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	2	799488-799619	1	PILER-CR	no		DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	TTTTCAATATTGGTGAT	17	0	0	NA	NA	NA	2	2	Orphan	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|274aa|up_9|NZ_CP040309.1_785646_786468_+	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism]	NA|383aa|up_8|NZ_CP040309.1_786923_788072_+	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit	NA|1074aa|up_7|NZ_CP040309.1_788089_791311_+	PRK05294, carB, carbamoyl-phosphate synthase large subunit	NA|132aa|up_6|NZ_CP040309.1_791571_791967_+	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF	NA|197aa|up_5|NZ_CP040309.1_792085_792676_-	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional	NA|262aa|up_4|NZ_CP040309.1_792681_793467_-	PRK03580, PRK03580, crotonobetainyl-CoA hydratase	NA|518aa|up_3|NZ_CP040309.1_793575_795129_-	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated	NA|406aa|up_2|NZ_CP040309.1_795202_796420_-	PRK03525, PRK03525, L-carnitine CoA-transferase	NA|381aa|up_1|NZ_CP040309.1_796548_797691_-	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated	NA|505aa|up_0|NZ_CP040309.1_797721_799236_-	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter	NA|257aa|down_0|NZ_CP040309.1_799709_800480_+	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed	NA|314aa|down_1|NZ_CP040309.1_800494_801436_+	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein	NA|429aa|down_2|NZ_CP040309.1_801486_802773_+	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional	NA|96aa|down_3|NZ_CP040309.1_802769_803057_+	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional	NA|444aa|down_4|NZ_CP040309.1_803114_804446_+	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily	NA|177aa|down_5|NZ_CP040309.1_804553_805084_+	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF	NA|621aa|down_6|NZ_CP040309.1_805076_806939_+	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional	NA|160aa|down_7|NZ_CP040309.1_807130_807610_+	PRK10769, folA, type 3 dihydrofolate reductase	NA|78aa|down_8|NZ_CP040309.1_807695_807929_+	COG5302, COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid [General function prediction only]	NA|105aa|down_9|NZ_CP040309.1_807931_808246_+	pfam01845, CcdB, CcdB protein
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	3	824389-824523	2	CRISPRCasFinder	no		DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCC	50	0	0	NA	NA	NA	1	1	Orphan	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA|251aa|up_4|NZ_CP040309.1_816342_817095_+,NA|190aa|down_7|NZ_CP040309.1_833564_834134_+	NA|274aa|up_9|NZ_CP040309.1_809477_810299_-	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA	NA|330aa|up_8|NZ_CP040309.1_810295_811285_-	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed	NA|429aa|up_7|NZ_CP040309.1_811284_812571_-	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional	NA|785aa|up_6|NZ_CP040309.1_812623_814978_-	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional	NA|272aa|up_5|NZ_CP040309.1_815232_816048_+	PRK09430, djlA, co-chaperone DjlA	NA|251aa|up_4|NZ_CP040309.1_816342_817095_+	NA	NA|220aa|up_3|NZ_CP040309.1_817512_818172_-	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA|969aa|up_2|NZ_CP040309.1_818183_821090_-	PRK04914, PRK04914, RNA polymerase-associated protein RapA	NA|784aa|up_1|NZ_CP040309.1_821253_823605_-	PRK05762, PRK05762, DNA polymerase II; Reviewed	NA|232aa|up_0|NZ_CP040309.1_823679_824375_-	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD	NA|501aa|down_0|NZ_CP040309.1_824574_826077_-	PRK02929, PRK02929, L-arabinose isomerase; Provisional	NA|567aa|down_1|NZ_CP040309.1_826087_827788_-	PRK04123, PRK04123, ribulokinase; Provisional	NA|293aa|down_2|NZ_CP040309.1_828126_829005_+	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC	NA|255aa|down_3|NZ_CP040309.1_829090_829855_+	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown]	NA|233aa|down_4|NZ_CP040309.1_829941_830640_-	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ	NA|537aa|down_5|NZ_CP040309.1_830623_832234_-	PRK09433, thiP, thiamine transporter membrane protein; Reviewed	NA|328aa|down_6|NZ_CP040309.1_832209_833193_-	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional	NA|190aa|down_7|NZ_CP040309.1_833564_834134_+	NA	NA|553aa|down_8|NZ_CP040309.1_834362_836021_-	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR	NA|44aa|down_9|NZ_CP040309.1_836109_836241_+	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	4	3615882-3615993	2	PILER-CR	no		DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Orphan	TTTTCTTACCTGATTCGGGTAA	22	1	1	3615951-3615976	NZ_CP040309.1_2322313-2322288	NA	2	2	Orphan	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA|47aa|up_9|NZ_CP040309.1_3612092_3612233_-,NA|34aa|up_4|NZ_CP040309.1_3613493_3613595_-,NA|94aa|up_3|NZ_CP040309.1_3613685_3613967_-,NA|66aa|up_2|NZ_CP040309.1_3614010_3614208_-,NA|95aa|up_1|NZ_CP040309.1_3614435_3614720_-,NA|94aa|down_9|NZ_CP040309.1_3622727_3623009_+	NA|47aa|up_9|NZ_CP040309.1_3612092_3612233_-	NA	NA|121aa|up_8|NZ_CP040309.1_3612229_3612592_-	PRK09786, PRK09786, endodeoxyribonuclease RUS; Reviewed	NA|97aa|up_7|NZ_CP040309.1_3612588_3612879_-	pfam07102, DUF1364, Protein of unknown function (DUF1364)	NA|57aa|up_6|NZ_CP040309.1_3612871_3613042_-	PRK09689, PRK09689, prophage protein NinE; Provisional	NA|152aa|up_5|NZ_CP040309.1_3613041_3613497_-	PRK09741, PRK09741, hypothetical protein; Provisional	NA|34aa|up_4|NZ_CP040309.1_3613493_3613595_-	NA	NA|94aa|up_3|NZ_CP040309.1_3613685_3613967_-	NA	NA|66aa|up_2|NZ_CP040309.1_3614010_3614208_-	NA	NA|95aa|up_1|NZ_CP040309.1_3614435_3614720_-	NA	NA|234aa|up_0|NZ_CP040309.1_3614716_3615418_-	pfam06992, Phage_lambda_P, Replication protein P	NA|180aa|down_0|NZ_CP040309.1_3616430_3616970_-	pfam06254, YdaT_toxin, Putative bacterial toxin ydaT	NA|231aa|down_1|NZ_CP040309.1_3617333_3618026_+	COG2932, COG2932, Predicted transcriptional regulator [Transcription]	NA|536aa|down_2|NZ_CP040309.1_3618132_3619740_+	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation	NA|97aa|down_3|NZ_CP040309.1_3620243_3620534_+	PRK11354, kil, FtsZ inhibitor protein; Reviewed	NA|99aa|down_4|NZ_CP040309.1_3620609_3620906_+	pfam06064, Gam, Host-nuclease inhibitor protein Gam	NA|262aa|down_5|NZ_CP040309.1_3620911_3621697_+	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet	NA|226aa|down_6|NZ_CP040309.1_3621693_3622371_+	pfam09588, YqaJ, YqaJ-like viral recombinase domain	NA|61aa|down_7|NZ_CP040309.1_3622370_3622553_+	pfam07026, DUF1317, Protein of unknown function (DUF1317)	NA|64aa|down_8|NZ_CP040309.1_3622525_3622717_+	pfam07131, DUF1382, Protein of unknown function (DUF1382)	NA|94aa|down_9|NZ_CP040309.1_3622727_3623009_+	NA
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	5	4280985-4281197	3,1,3	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Type I-E	CGGTTTATCCCCGCTGGCGCGGGGAACAC,CGGTTTATCCCCGCTGGCGCGGGGAACACA,CGGTTTATCCCCGCTGGCGCGGGGAACACA	29,30,30	0	0	NA	NA	I-E:I-E:I-E	3,3,2	3	TypeI-E	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|254aa|up_9|NZ_CP040309.1_4272797_4273559_-	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional	NA|350aa|up_8|NZ_CP040309.1_4273539_4274589_-	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed	NA|160aa|up_7|NZ_CP040309.1_4274585_4275065_-	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed	NA|237aa|up_6|NZ_CP040309.1_4275064_4275775_-	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase	NA|104aa|up_5|NZ_CP040309.1_4275793_4276105_-	PRK00888, ftsB, cell division protein FtsB; Reviewed	NA|108aa|up_4|NZ_CP040309.1_4276298_4276622_-	pfam12084, DUF3561, Protein of unknown function (DUF3561)	NA|202aa|up_3|NZ_CP040309.1_4276671_4277277_-	PRK03846, PRK03846, adenylylsulfate kinase; Provisional	NA|476aa|up_2|NZ_CP040309.1_4277276_4278704_-	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional	NA|303aa|up_1|NZ_CP040309.1_4278705_4279614_-	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD	NA|346aa|up_0|NZ_CP040309.1_4279865_4280903_+	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional	cas2|98aa|down_0|NZ_CP040309.1_4281292_4281586_-	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional	cas1|308aa|down_1|NZ_CP040309.1_4281582_4282506_-	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI	cas6e|217aa|down_2|NZ_CP040309.1_4282502_4283153_-	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI	cas5|249aa|down_3|NZ_CP040309.1_4283134_4283881_-	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5	cas7|352aa|down_4|NZ_CP040309.1_4283891_4284947_-	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI	cse2gr11|179aa|down_5|NZ_CP040309.1_4284958_4285495_-	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2	cas8e|521aa|down_6|NZ_CP040309.1_4285491_4287054_-	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1	cas3|900aa|down_7|NZ_CP040309.1_4287151_4289851_-	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms]	NA|51aa|down_8|NZ_CP040309.1_4290042_4290195_-	pfam01848, HOK_GEF, Hok/gef family	NA|245aa|down_9|NZ_CP040309.1_4290458_4291193_-	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase
GCF_009432415.1_ASM943241v1	NZ_CP040309	Escherichia coli strain 21B8 chromosome, complete genome	6	4306827-4306915	4	CRISPRCasFinder	no	cas3	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	Unclear	GGTTTATCCCCACTGGCGCGGGGAACTC	28	0	0	NA	NA	I-E	1	1	Unclear	DEDDh,c2c9_V-U4,cas3,DinG,PrimPol,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,PD-DExK	NA,NA	NA|600aa|up_9|NZ_CP040309.1_4292978_4294778_-	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	NA|122aa|up_8|NZ_CP040309.1_4295093_4295459_+	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS)	NA|424aa|up_7|NZ_CP040309.1_4295536_4296808_+	PRK10015, PRK10015, oxidoreductase; Provisional	NA|87aa|up_6|NZ_CP040309.1_4296798_4297059_+	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion]	NA|192aa|up_5|NZ_CP040309.1_4297075_4297651_+	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]	NA|260aa|up_4|NZ_CP040309.1_4298655_4299435_-	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion]	NA|485aa|up_3|NZ_CP040309.1_4300842_4302297_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|262aa|up_2|NZ_CP040309.1_4302366_4303152_-	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs	NA|426aa|up_1|NZ_CP040309.1_4303470_4304748_+	cd06174, MFS, Major Facilitator Superfamily	NA|493aa|up_0|NZ_CP040309.1_4304774_4306253_+	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins	NA|224aa|down_0|NZ_CP040309.1_4307254_4307926_-	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	NA|207aa|down_1|NZ_CP040309.1_4308080_4308701_+	COG1704, LemA, Uncharacterized conserved protein [Function unknown]	NA|225aa|down_2|NZ_CP040309.1_4308714_4309389_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|383aa|down_3|NZ_CP040309.1_4309622_4310771_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|305aa|down_4|NZ_CP040309.1_4310767_4311682_+	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only]	NA|433aa|down_5|NZ_CP040309.1_4311741_4313040_-	PRK00077, eno, enolase; Provisional	NA|546aa|down_6|NZ_CP040309.1_4313127_4314765_-	PRK05380, pyrG, CTP synthetase; Validated	NA|264aa|down_7|NZ_CP040309.1_4314992_4315784_-	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed	NA|112aa|down_8|NZ_CP040309.1_4315854_4316190_-	PRK09907, PRK09907, endoribonuclease MazF	NA|83aa|down_9|NZ_CP040309.1_4316189_4316438_-	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE
