assembly_id	genome_id	genome_def	crispr_array_locus_merge	crispr_array_location_merge	crispr_locus_id	crispr_pred_method	array_in_prot	prot_within_array_20000	prot_in_genome	crispr_type_by_cas_prot	consensus_repeat	repeat_length	self-targeting_spacer_number	self-targeting_target_number	spacer_location	protospacer_location	repeat_type	spacer_locus_num	spacer_num	correct_crispr_type	genome_cas_prots	unknown_protein_around_crispr	L10	L10_domain	L9	L9_domain	L8	L8_domain	L7	L7_domain	L6	L6_domain	L5	L5_domain	L4	L4_domain	L3	L3_domain	L2	L2_domain	L1	L1_domain	R1	R1_domain	R2	R2_domain	R3	R3_domain	R4	R4_domain	R5	R5_domain	R6	R6_domain	R7	R7_domain	R8	R8_domain	R9	R9_domain	R10	R10_domain
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	1	136362-136914	1	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CCGGCGCCGCCGGCCCCGCCGTTGCCGA	28	2	11	136441-136457|136441-136457|136441-136457|136441-136457|136441-136457|136441-136457|136441-136457|136762-136781|136762-136781|136762-136781|136762-136781	NZ_CP046309.1_2847695-2847711|NZ_CP046309.1_2847863-2847879|NZ_CP046309.1_1143878-1143862|NZ_CP046309.1_1143977-1143961|NZ_CP046309.1_1144058-1144042|NZ_CP046309.1_3351520-3351504|NZ_CP046309.1_3353151-3353135|NZ_CP046309.1_513188-513207|NZ_CP046309.1_2844981-2845000|NZ_CP046309.1_2847944-2847963|NZ_CP046309.1_3336022-3336003	NA	10	10	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|222aa|up_2|NZ_CP046309.1_132234_132900_+,NA	NA|410aa|up_9|NZ_CP046309.1_124627_125857_+	pfam00823, PPE, PPE family	NA|469aa|up_8|NZ_CP046309.1_125988_127395_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|119aa|up_7|NZ_CP046309.1_127639_127996_+	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|235aa|up_6|NZ_CP046309.1_128149_128854_+	COG1285, SapB, Uncharacterized membrane protein [Function unknown]	NA|401aa|up_5|NZ_CP046309.1_128863_130066_-	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]	NA|144aa|up_4|NZ_CP046309.1_130387_130819_-	pfam13827, DUF4189, Domain of unknown function (DUF4189)	NA|301aa|up_3|NZ_CP046309.1_131227_132130_+	COG3000, ERG3, Sterol desaturase [Lipid metabolism]	NA|222aa|up_2|NZ_CP046309.1_132234_132900_+	NA	NA|246aa|up_1|NZ_CP046309.1_132962_133700_+	pfam13305, WHG, WHG domain	NA|488aa|up_0|NZ_CP046309.1_134300_135764_+	PRK07121, PRK07121, FAD-binding protein	NA|640aa|down_0|NZ_CP046309.1_137481_139401_-	COG4178, COG4178, ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]	NA|548aa|down_1|NZ_CP046309.1_139471_141115_+	PRK05858, PRK05858, acetolactate synthase	NA|809aa|down_2|NZ_CP046309.1_141129_143556_+	PRK12326, PRK12326, preprotein translocase subunit SecA; Reviewed	NA|210aa|down_3|NZ_CP046309.1_143752_144382_+	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism]	NA|308aa|down_4|NZ_CP046309.1_144374_145298_+	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown]	NA|111aa|down_5|NZ_CP046309.1_145359_145692_+	COG3856, Sbp, Uncharacterized conserved protein (small basic protein) [Function unknown]	NA|293aa|down_6|NZ_CP046309.1_145708_146587_+	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown]	NA|135aa|down_7|NZ_CP046309.1_146624_147029_+	PRK01202, PRK01202, glycine cleavage system protein GcvH	NA|163aa|down_8|NZ_CP046309.1_147268_147757_+	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms]	NA|248aa|down_9|NZ_CP046309.1_147753_148497_+	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	2	162906-163160	1	CRT	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	GCCNCCGTCGCCGCCNNTGCC	21	2	3	162987-163004|162987-163004|163077-163094	NZ_CP046309.1_2913315-2913298|NZ_CP046309.1_3120918-3120901|NZ_CP046309.1_1541122-1541105	NA	5	5	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|88aa|up_0|NZ_CP046309.1_162265_162529_-,NA	NA|165aa|up_9|NZ_CP046309.1_148615_149110_+	pfam02577, DNase-RNase, Bifunctional nuclease	NA|226aa|up_8|NZ_CP046309.1_149457_150135_+	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators	NA|942aa|up_7|NZ_CP046309.1_150493_153319_+	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase	NA|287aa|up_6|NZ_CP046309.1_153545_154406_-	PRK03204, PRK03204, haloalkane dehalogenase; Provisional	NA|289aa|up_5|NZ_CP046309.1_154446_155313_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|629aa|up_4|NZ_CP046309.1_155317_157204_-	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c	NA|678aa|up_3|NZ_CP046309.1_157219_159253_-	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF)	NA|742aa|up_2|NZ_CP046309.1_159372_161598_-	PRK02999, PRK02999, malate synthase G; Provisional	NA|132aa|up_1|NZ_CP046309.1_161873_162269_-	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]	NA|88aa|up_0|NZ_CP046309.1_162265_162529_-	NA	NA|346aa|down_0|NZ_CP046309.1_164297_165335_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|456aa|down_1|NZ_CP046309.1_165334_166702_-	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only]	NA|479aa|down_2|NZ_CP046309.1_166875_168312_-	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein	NA|484aa|down_3|NZ_CP046309.1_168347_169799_-	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase	NA|317aa|down_4|NZ_CP046309.1_169828_170779_-	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase	NA|139aa|down_5|NZ_CP046309.1_170793_171210_-	COG3682, COG3682, Predicted transcriptional regulator [Transcription]	NA|141aa|down_6|NZ_CP046309.1_171487_171910_+	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]	NA|101aa|down_7|NZ_CP046309.1_171958_172261_+	pfam00547, Urease_gamma, Urease, gamma subunit	NA|105aa|down_8|NZ_CP046309.1_172257_172572_+	PRK13202, ureB, urease subunit beta; Reviewed	NA|578aa|down_9|NZ_CP046309.1_172571_174305_+	PRK13206, ureC, urease subunit alpha; Reviewed
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	3	245637-245856	2	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	GTGCCAGCCGGAATCGTGATCGGCGGAACCGTCACCGACGGAATACTCA	49	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|157aa|up_9|NZ_CP046309.1_227105_227576_-,NA|136aa|up_2|NZ_CP046309.1_234601_235009_-,NA|127aa|down_5|NZ_CP046309.1_253372_253753_-	NA|157aa|up_9|NZ_CP046309.1_227105_227576_-	NA	NA|216aa|up_8|NZ_CP046309.1_227915_228563_-	pfam14081, DUF4262, Domain of unknown function (DUF4262)	NA|741aa|up_7|NZ_CP046309.1_228569_230792_-	PRK15061, PRK15061, catalase/peroxidase	NA|148aa|up_6|NZ_CP046309.1_230829_231273_-	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]	NA|198aa|up_5|NZ_CP046309.1_231386_231980_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|202aa|up_4|NZ_CP046309.1_232062_232668_-	COG1881, COG1881, Phospholipid-binding protein [General function prediction only]	NA|251aa|up_3|NZ_CP046309.1_233871_234624_+	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|136aa|up_2|NZ_CP046309.1_234601_235009_-	NA	NA|767aa|up_1|NZ_CP046309.1_235143_237444_+	PLN02892, PLN02892, isocitrate lyase	NA|421aa|up_0|NZ_CP046309.1_241827_243089_+	PHA02517, PHA02517, putative transposase OrfB; Reviewed	NA|155aa|down_0|NZ_CP046309.1_247883_248348_-	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|down_1|NZ_CP046309.1_248445_249309_+	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like	NA|467aa|down_2|NZ_CP046309.1_249217_250618_-	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|372aa|down_3|NZ_CP046309.1_250889_252005_+	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]	NA|447aa|down_4|NZ_CP046309.1_251995_253336_+	pfam00144, Beta-lactamase, Beta-lactamase	NA|127aa|down_5|NZ_CP046309.1_253372_253753_-	NA	NA|621aa|down_6|NZ_CP046309.1_253909_255772_+	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional	NA|160aa|down_7|NZ_CP046309.1_255779_256259_-	pfam09167, DUF1942, Domain of unknown function (DUF1942)	NA|258aa|down_8|NZ_CP046309.1_256495_257269_+	COG3361, COG3361, Uncharacterized conserved protein [Function unknown]	NA|256aa|down_9|NZ_CP046309.1_257272_258040_-	PRK05867, PRK05867, SDR family oxidoreductase
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	4	1208473-1209328	1,3,2	PILER-CR,CRISPRCasFinder,CRT	no	c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	11,11,11	11	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|85aa|up_7|NZ_CP046309.1_1201753_1202008_-,NA|135aa|up_6|NZ_CP046309.1_1202155_1202560_+,NA|64aa|up_5|NZ_CP046309.1_1202556_1202748_+,NA|86aa|up_4|NZ_CP046309.1_1204333_1204591_+,NA|104aa|up_3|NZ_CP046309.1_1204695_1205007_+,NA|203aa|up_2|NZ_CP046309.1_1205426_1206035_+,NA	NA|348aa|up_9|NZ_CP046309.1_1200068_1201112_-	COG5586, COG5586, Uncharacterized conserved protein [Function unknown]	NA|92aa|up_8|NZ_CP046309.1_1201302_1201578_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_7|NZ_CP046309.1_1201753_1202008_-	NA	NA|135aa|up_6|NZ_CP046309.1_1202155_1202560_+	NA	NA|64aa|up_5|NZ_CP046309.1_1202556_1202748_+	NA	NA|86aa|up_4|NZ_CP046309.1_1204333_1204591_+	NA	NA|104aa|up_3|NZ_CP046309.1_1204695_1205007_+	NA	NA|203aa|up_2|NZ_CP046309.1_1205426_1206035_+	NA	NA|470aa|up_1|NZ_CP046309.1_1206105_1207515_+	pfam00665, rve, Integrase core domain	NA|271aa|up_0|NZ_CP046309.1_1207511_1208324_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|down_0|NZ_CP046309.1_1209412_1210674_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_1|NZ_CP046309.1_1212739_1213081_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_2|NZ_CP046309.1_1213081_1214098_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_3|NZ_CP046309.1_1214110_1215259_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_4|NZ_CP046309.1_1215354_1216482_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_5|NZ_CP046309.1_1216478_1217387_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_6|NZ_CP046309.1_1217367_1218078_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_7|NZ_CP046309.1_1218087_1218462_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_8|NZ_CP046309.1_1218458_1220897_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_9|NZ_CP046309.1_1220893_1221838_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	5	1210753-1212691	4,3,2	CRISPRCasFinder,CRT,PILER-CR	no	cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Type III-D,Type III-A,Type III-C,Type III-B	GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC,GTTTCCGTCCCCTCTCGGGGTTTTGGGTCTGACGAC	36,36,36	0	0	NA	NA	II-B,III-A:II-B,III-A:II-B,III-A	26,26,23	26	TypeIII-D,TypeIII-A,TypeIII-C,TypeIII-B	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|85aa|up_8|NZ_CP046309.1_1201753_1202008_-,NA|135aa|up_7|NZ_CP046309.1_1202155_1202560_+,NA|64aa|up_6|NZ_CP046309.1_1202556_1202748_+,NA|86aa|up_5|NZ_CP046309.1_1204333_1204591_+,NA|104aa|up_4|NZ_CP046309.1_1204695_1205007_+,NA|203aa|up_3|NZ_CP046309.1_1205426_1206035_+,NA	NA|92aa|up_9|NZ_CP046309.1_1201302_1201578_+	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown]	NA|85aa|up_8|NZ_CP046309.1_1201753_1202008_-	NA	NA|135aa|up_7|NZ_CP046309.1_1202155_1202560_+	NA	NA|64aa|up_6|NZ_CP046309.1_1202556_1202748_+	NA	NA|86aa|up_5|NZ_CP046309.1_1204333_1204591_+	NA	NA|104aa|up_4|NZ_CP046309.1_1204695_1205007_+	NA	NA|203aa|up_3|NZ_CP046309.1_1205426_1206035_+	NA	NA|470aa|up_2|NZ_CP046309.1_1206105_1207515_+	pfam00665, rve, Integrase core domain	NA|271aa|up_1|NZ_CP046309.1_1207511_1208324_+	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]	NA|421aa|up_0|NZ_CP046309.1_1209412_1210674_-	PHA02517, PHA02517, putative transposase OrfB; Reviewed	cas2|114aa|down_0|NZ_CP046309.1_1212739_1213081_-	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms]	cas1|339aa|down_1|NZ_CP046309.1_1213081_1214098_-	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1	csm6|383aa|down_2|NZ_CP046309.1_1214110_1215259_-	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6	csm5gr7|376aa|down_3|NZ_CP046309.1_1215354_1216482_-	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms]	csm4gr5|303aa|down_4|NZ_CP046309.1_1216478_1217387_-	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	csm3gr7|237aa|down_5|NZ_CP046309.1_1217367_1218078_-	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3	csm2gr11|125aa|down_6|NZ_CP046309.1_1218087_1218462_-	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2	cas10|813aa|down_7|NZ_CP046309.1_1218458_1220897_-	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10	cas6|315aa|down_8|NZ_CP046309.1_1220893_1221838_-	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense    mechanisms]	NA|182aa|down_9|NZ_CP046309.1_1222015_1222561_-	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown]
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	6	1837885-1838426	4	CRT	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CCGCCGTTNCCNCCGTTGCCGCC	23	0	0	NA	NA	NA	7	7	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA|96aa|down_3|NZ_CP046309.1_1852631_1852919_-,NA|87aa|down_8|NZ_CP046309.1_1866039_1866300_-	NA|282aa|up_9|NZ_CP046309.1_1815424_1816270_-	pfam05305, DUF732, Protein of unknown function (DUF732)	NA|147aa|up_8|NZ_CP046309.1_1816744_1817185_+	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators	NA|290aa|up_7|NZ_CP046309.1_1817218_1818088_-	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD	NA|337aa|up_6|NZ_CP046309.1_1818108_1819119_-	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed	NA|211aa|up_5|NZ_CP046309.1_1819403_1820036_+	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional	NA|410aa|up_4|NZ_CP046309.1_1820102_1821332_-	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase	NA|450aa|up_3|NZ_CP046309.1_1821614_1822964_+	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated	NA|380aa|up_2|NZ_CP046309.1_1822975_1824115_+	PRK00175, metX, homoserine O-acetyltransferase; Provisional	NA|244aa|up_1|NZ_CP046309.1_1824111_1824843_+	pfam08241, Methyltransf_11, Methyltransferase domain	NA|3104aa|up_0|NZ_CP046309.1_1824851_1834163_-	pfam00823, PPE, PPE family	NA|86aa|down_0|NZ_CP046309.1_1840499_1840757_-	pfam11222, DUF3017, Protein of unknown function (DUF3017)	NA|149aa|down_1|NZ_CP046309.1_1851113_1851560_+	pfam01548, DEDD_Tnp_IS110, Transposase	NA|281aa|down_2|NZ_CP046309.1_1851596_1852439_-	pfam01610, DDE_Tnp_ISL3, Transposase	NA|96aa|down_3|NZ_CP046309.1_1852631_1852919_-	NA	NA|3717aa|down_4|NZ_CP046309.1_1853255_1864406_-	pfam00823, PPE, PPE family	NA|265aa|down_5|NZ_CP046309.1_1864649_1865444_-	pfam08031, BBE, Berberine and berberine like	NA|124aa|down_6|NZ_CP046309.1_1865525_1865897_-	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion]	NA|137aa|down_7|NZ_CP046309.1_1865794_1866205_-	pfam01565, FAD_binding_4, FAD binding domain	NA|87aa|down_8|NZ_CP046309.1_1866039_1866300_-	NA	NA|130aa|down_9|NZ_CP046309.1_1866414_1866804_+	pfam05305, DUF732, Protein of unknown function (DUF732)
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	7	1943998-1944087	5	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CCAGGCGTTGGGCTGGCTGCCGAT	24	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|77aa|up_7|NZ_CP046309.1_1937392_1937623_+,NA|121aa|up_6|NZ_CP046309.1_1937726_1938089_-,NA|73aa|up_2|NZ_CP046309.1_1942063_1942282_-,NA|121aa|down_0|NZ_CP046309.1_1945072_1945435_-,NA|52aa|down_2|NZ_CP046309.1_1947276_1947432_-,NA|52aa|down_3|NZ_CP046309.1_1947456_1947612_-,NA|238aa|down_6|NZ_CP046309.1_1951647_1952361_-	NA|169aa|up_9|NZ_CP046309.1_1935703_1936210_-	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only]	NA|409aa|up_8|NZ_CP046309.1_1936206_1937433_-	PRK00053, alr, alanine racemase; Reviewed	NA|77aa|up_7|NZ_CP046309.1_1937392_1937623_+	NA	NA|121aa|up_6|NZ_CP046309.1_1937726_1938089_-	NA	NA|177aa|up_5|NZ_CP046309.1_1938251_1938782_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|177aa|up_4|NZ_CP046309.1_1939048_1939579_+	pfam00823, PPE, PPE family	NA|725aa|up_3|NZ_CP046309.1_1939896_1942071_-	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair]	NA|73aa|up_2|NZ_CP046309.1_1942063_1942282_-	NA	NA|100aa|up_1|NZ_CP046309.1_1942776_1943076_+	pfam00934, PE, PE family	NA|181aa|up_0|NZ_CP046309.1_1943161_1943704_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|121aa|down_0|NZ_CP046309.1_1945072_1945435_-	NA	NA|179aa|down_1|NZ_CP046309.1_1945597_1946134_+	pfam00823, PPE, PPE family	NA|52aa|down_2|NZ_CP046309.1_1947276_1947432_-	NA	NA|52aa|down_3|NZ_CP046309.1_1947456_1947612_-	NA	NA|461aa|down_4|NZ_CP046309.1_1948804_1950187_-	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha	NA|474aa|down_5|NZ_CP046309.1_1950224_1951646_-	pfam01256, Carb_kinase, Carbohydrate kinase	NA|238aa|down_6|NZ_CP046309.1_1951647_1952361_-	NA	NA|285aa|down_7|NZ_CP046309.1_1952371_1953226_-	pfam14494, DUF4436, Domain of unknown function (DUF4436)	NA|625aa|down_8|NZ_CP046309.1_1953447_1955322_-	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase	NA|159aa|down_9|NZ_CP046309.1_1955343_1955820_+	pfam10708, DUF2510, Protein of unknown function (DUF2510)
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	8	2044521-2046113	5	CRT	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CGGCGGNNCCGGCGGNNNNGGCGGNNCCGGCGG	33	17	23	2044554-2044613|2044647-2044688|2044722-2044760|2044722-2044760|2044794-2044832|2044866-2044907|2044941-2044970|2045085-2045120|2045154-2045210|2045244-2045288|2045322-2045360|2045322-2045360|2045394-2045429|2045394-2045429|2045463-2045483|2045463-2045483|2045463-2045483|2045607-2045639|2045673-2045729|2045763-2045798|2045763-2045798|2045940-2045990|2046024-2046080	NZ_CP046309.1_2046201-2046260|NZ_CP046309.1_2046294-2046335|NZ_CP046309.1_2046369-2046407|NZ_CP046309.1_2030127-2030165|NZ_CP046309.1_2046441-2046479|NZ_CP046309.1_2046513-2046554|NZ_CP046309.1_2046588-2046617|NZ_CP046309.1_2046660-2046695|NZ_CP046309.1_2046729-2046785|NZ_CP046309.1_2046819-2046863|NZ_CP046309.1_2046369-2046407|NZ_CP046309.1_2030127-2030165|NZ_CP046309.1_2044449-2044484|NZ_CP046309.1_2046096-2046131|NZ_CP046309.1_2030268-2030288|NZ_CP046309.1_3488030-3488010|NZ_CP046309.1_2046342-2046362|NZ_CP046309.1_2046303-2046335|NZ_CP046309.1_2046369-2046425|NZ_CP046309.1_2044467-2044502|NZ_CP046309.1_2046114-2046149|NZ_CP046309.1_2046285-2046335|NZ_CP046309.1_2046369-2046425	NA	20	20	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA	NA|318aa|up_9|NZ_CP046309.1_2018217_2019171_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP046309.1_2019195_2019387_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP046309.1_2019601_2020804_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP046309.1_2020828_2021950_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP046309.1_2022020_2023529_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1418aa|up_4|NZ_CP046309.1_2023699_2027953_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP046309.1_2034132_2035680_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP046309.1_2035676_2036513_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1909aa|up_1|NZ_CP046309.1_2036872_2042599_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP046309.1_2042727_2043384_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP046309.1_2048771_2050418_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|399aa|down_1|NZ_CP046309.1_2050974_2052171_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_2|NZ_CP046309.1_2052199_2052910_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_3|NZ_CP046309.1_2052974_2054018_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_4|NZ_CP046309.1_2054170_2055082_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_5|NZ_CP046309.1_2055097_2056162_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_6|NZ_CP046309.1_2056178_2057363_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_7|NZ_CP046309.1_2057404_2058436_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD	NA|175aa|down_8|NZ_CP046309.1_2058449_2058974_-	COG0663, PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]	NA|387aa|down_9|NZ_CP046309.1_2059088_2060249_+	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH)
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	9	2046846-2047911	6	CRT	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CGGCGGNACCGGCGGCNNNGGCGGCNCCGGCGGC	34	9	9	2046943-2046998|2047033-2047082|2047117-2047154|2047270-2047304|2047339-2047394|2047429-2047472|2047576-2047613|2047648-2047697|2047732-2047769	NZ_CP046309.1_2046415-2046470|NZ_CP046309.1_2046505-2046554|NZ_CP046309.1_2046580-2046617|NZ_CP046309.1_2046661-2046695|NZ_CP046309.1_2046730-2046785|NZ_CP046309.1_2046820-2046863|NZ_CP046309.1_2046442-2046479|NZ_CP046309.1_2046514-2046563|NZ_CP046309.1_2046589-2046626	NA	13	13	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA	NA|318aa|up_9|NZ_CP046309.1_2018217_2019171_-	PRK07792, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional	NA|64aa|up_8|NZ_CP046309.1_2019195_2019387_-	COG1141, Fer, Ferredoxin [Energy production and conversion]	NA|401aa|up_7|NZ_CP046309.1_2019601_2020804_+	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|374aa|up_6|NZ_CP046309.1_2020828_2021950_+	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism]	NA|503aa|up_5|NZ_CP046309.1_2022020_2023529_+	PRK07867, PRK07867, acyl-CoA synthetase; Validated	NA|1418aa|up_4|NZ_CP046309.1_2023699_2027953_+	pfam00934, PE, PE family	NA|516aa|up_3|NZ_CP046309.1_2034132_2035680_-	PRK07586, PRK07586, acetolactate synthase large subunit	NA|279aa|up_2|NZ_CP046309.1_2035676_2036513_-	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]	NA|1909aa|up_1|NZ_CP046309.1_2036872_2042599_+	pfam00934, PE, PE family	NA|219aa|up_0|NZ_CP046309.1_2042727_2043384_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|549aa|down_0|NZ_CP046309.1_2048771_2050418_-	PRK07798, PRK07798, acyl-CoA synthetase; Validated	NA|399aa|down_1|NZ_CP046309.1_2050974_2052171_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|237aa|down_2|NZ_CP046309.1_2052199_2052910_+	pfam06314, ADC, Acetoacetate decarboxylase (ADC)	NA|348aa|down_3|NZ_CP046309.1_2052974_2054018_-	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family	NA|304aa|down_4|NZ_CP046309.1_2054170_2055082_+	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]	NA|355aa|down_5|NZ_CP046309.1_2055097_2056162_+	PRK07937, PRK07937, lipid-transfer protein; Provisional	NA|395aa|down_6|NZ_CP046309.1_2056178_2057363_+	PRK08313, PRK08313, thiolase domain-containing protein	NA|344aa|down_7|NZ_CP046309.1_2057404_2058436_+	cd14952, NHL_PKND_like, NHL repeat domain of the protein kinase PknD	NA|175aa|down_8|NZ_CP046309.1_2058449_2058974_-	COG0663, PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]	NA|387aa|down_9|NZ_CP046309.1_2059088_2060249_+	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH)
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	10	2207439-2207527	6	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	GCTCGGCGACGATGCGGGCCGGATGACGGCC	31	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|257aa|up_8|NZ_CP046309.1_2198025_2198796_-,NA|119aa|up_3|NZ_CP046309.1_2203930_2204287_+,NA|52aa|up_2|NZ_CP046309.1_2204386_2204542_+,NA|233aa|up_0|NZ_CP046309.1_2206543_2207242_-,NA|126aa|down_6|NZ_CP046309.1_2212762_2213140_+	NA|288aa|up_9|NZ_CP046309.1_2196407_2197271_+	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490	NA|257aa|up_8|NZ_CP046309.1_2198025_2198796_-	NA	NA|549aa|up_7|NZ_CP046309.1_2198792_2200439_-	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]	NA|288aa|up_6|NZ_CP046309.1_2200435_2201299_-	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|309aa|up_5|NZ_CP046309.1_2201291_2202218_-	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]	NA|542aa|up_4|NZ_CP046309.1_2202219_2203845_-	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold	NA|119aa|up_3|NZ_CP046309.1_2203930_2204287_+	NA	NA|52aa|up_2|NZ_CP046309.1_2204386_2204542_+	NA	NA|652aa|up_1|NZ_CP046309.1_2204552_2206508_+	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional	NA|233aa|up_0|NZ_CP046309.1_2206543_2207242_-	NA	NA|173aa|down_0|NZ_CP046309.1_2207587_2208106_+	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III	NA|328aa|down_1|NZ_CP046309.1_2208106_2209090_+	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]	NA|398aa|down_2|NZ_CP046309.1_2209082_2210276_-	pfam13365, Trypsin_2, Trypsin-like peptidase domain	NA|274aa|down_3|NZ_CP046309.1_2210281_2211103_-	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes	NA|228aa|down_4|NZ_CP046309.1_2211234_2211918_-	cd02966, TlpA_like_family, TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins	NA|246aa|down_5|NZ_CP046309.1_2211917_2212655_-	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]	NA|126aa|down_6|NZ_CP046309.1_2212762_2213140_+	NA	NA|225aa|down_7|NZ_CP046309.1_2213238_2213913_+	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]	NA|265aa|down_8|NZ_CP046309.1_2214018_2214813_-	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain	NA|152aa|down_9|NZ_CP046309.1_2214819_2215275_-	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	11	2844245-2844355	3	PILER-CR	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CCGCCGTTGCCGCCGTTGCCGATC	24	0	0	NA	NA	NA	2	2	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|61aa|up_0|NZ_CP046309.1_2842577_2842760_-,NA	NA|398aa|up_9|NZ_CP046309.1_2832755_2833949_-	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair]	NA|561aa|up_8|NZ_CP046309.1_2833984_2835667_+	PRK07788, PRK07788, acyl-CoA synthetase; Validated	NA|732aa|up_7|NZ_CP046309.1_2835683_2837879_-	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26	NA|378aa|up_6|NZ_CP046309.1_2837992_2839126_-	pfam12146, Hydrolase_4, Serine aminopeptidase, S33	NA|207aa|up_5|NZ_CP046309.1_2839122_2839743_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|194aa|up_4|NZ_CP046309.1_2839839_2840421_+	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	NA|242aa|up_3|NZ_CP046309.1_2840350_2841076_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|307aa|up_2|NZ_CP046309.1_2841165_2842086_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	NA|143aa|up_1|NZ_CP046309.1_2842125_2842554_-	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins	NA|61aa|up_0|NZ_CP046309.1_2842577_2842760_-	NA	NA|900aa|down_0|NZ_CP046309.1_2845925_2848625_-	pfam00934, PE, PE family	NA|838aa|down_1|NZ_CP046309.1_2848874_2851388_-	pfam00934, PE, PE family	NA|537aa|down_2|NZ_CP046309.1_2851678_2853289_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|303aa|down_3|NZ_CP046309.1_2853312_2854221_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|632aa|down_4|NZ_CP046309.1_2854444_2856340_+	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA	NA|539aa|down_5|NZ_CP046309.1_2856336_2857953_+	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B	NA|1331aa|down_6|NZ_CP046309.1_2857949_2861942_+	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa	NA|103aa|down_7|NZ_CP046309.1_2861938_2862247_+	pfam00934, PE, PE family	NA|514aa|down_8|NZ_CP046309.1_2862249_2863791_+	pfam00823, PPE, PPE family	NA|98aa|down_9|NZ_CP046309.1_2863839_2864133_+	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	12	3205599-3205675	7	CRISPRCasFinder	no	c2c9_V-U4	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Type V-U4	TGAGGTGCGGCGTGAGCGCGGGT	23	0	0	NA	NA	NA	1	1	TypeV-U4	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA	NA|136aa|up_9|NZ_CP046309.1_3191494_3191902_+	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins	NA|229aa|up_8|NZ_CP046309.1_3191961_3192648_-	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN	NA|878aa|up_7|NZ_CP046309.1_3192801_3195435_+	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]	NA|796aa|up_6|NZ_CP046309.1_3195457_3197845_-	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region	NA|241aa|up_5|NZ_CP046309.1_3197982_3198705_+	COG2186, FadR, Transcriptional regulators [Transcription]	NA|266aa|up_4|NZ_CP046309.1_3198701_3199499_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|296aa|up_3|NZ_CP046309.1_3199500_3200388_+	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|405aa|up_2|NZ_CP046309.1_3200393_3201608_+	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative	NA|344aa|up_1|NZ_CP046309.1_3201604_3202636_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|482aa|up_0|NZ_CP046309.1_3202632_3204078_+	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein	NA|517aa|down_0|NZ_CP046309.1_3206810_3208361_+	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]	NA|131aa|down_1|NZ_CP046309.1_3208412_3208805_-	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins	NA|86aa|down_2|NZ_CP046309.1_3208801_3209059_-	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]	NA|412aa|down_3|NZ_CP046309.1_3209241_3210477_-	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only]	NA|138aa|down_4|NZ_CP046309.1_3210727_3211141_-	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins	NA|79aa|down_5|NZ_CP046309.1_3211137_3211374_-	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription]	NA|169aa|down_6|NZ_CP046309.1_3211477_3211984_-	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms]	NA|157aa|down_7|NZ_CP046309.1_3212097_3212568_-	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB	NA|254aa|down_8|NZ_CP046309.1_3212611_3213373_-	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]	NA|104aa|down_9|NZ_CP046309.1_3213429_3213741_+	pfam03413, PepSY, Peptidase propeptide and YPEB domain
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	13	3441243-3442189	7	CRT	no	csa3	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Type I-A	CGGGGCCGGCGGNNCCGGCGG	21	1	3	3442025-3442060|3442025-3442060|3442025-3442060	NZ_CP046309.1_3728776-3728811|NZ_CP046309.1_512889-512854|NZ_CP046309.1_3188701-3188666	NA	19	19	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA|184aa|down_1|NZ_CP046309.1_3446198_3446750_-,NA|81aa|down_7|NZ_CP046309.1_3452210_3452453_+	NA|685aa|up_9|NZ_CP046309.1_3428879_3430934_-	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain	NA|390aa|up_8|NZ_CP046309.1_3431099_3432269_-	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family	NA|339aa|up_7|NZ_CP046309.1_3432356_3433373_-	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain	NA|220aa|up_6|NZ_CP046309.1_3433534_3434194_-	COG1309, AcrR, Transcriptional regulator [Transcription]	NA|352aa|up_5|NZ_CP046309.1_3434256_3435312_+	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown]	csa3|131aa|up_4|NZ_CP046309.1_3435363_3435756_-	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor	NA|141aa|up_3|NZ_CP046309.1_3435813_3436236_-	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis]	NA|97aa|up_2|NZ_CP046309.1_3436197_3436488_+	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair]	NA|302aa|up_1|NZ_CP046309.1_3436592_3437498_+	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]	NA|272aa|up_0|NZ_CP046309.1_3437516_3438332_-	TIGR04255, hypothetical_protein, TIGR04255 family protein	NA|215aa|down_0|NZ_CP046309.1_3445573_3446218_+	pfam14032, PknH_C, PknH-like extracellular domain	NA|184aa|down_1|NZ_CP046309.1_3446198_3446750_-	NA	NA|241aa|down_2|NZ_CP046309.1_3446830_3447553_-	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction    only]	NA|343aa|down_3|NZ_CP046309.1_3447623_3448652_-	COG4861, COG4861, Uncharacterized protein conserved in bacteria [Function unknown]	NA|257aa|down_4|NZ_CP046309.1_3449340_3450111_+	pfam01427, Peptidase_M15, D-ala-D-ala dipeptidase	NA|271aa|down_5|NZ_CP046309.1_3450197_3451010_+	pfam13847, Methyltransf_31, Methyltransferase domain	NA|286aa|down_6|NZ_CP046309.1_3451077_3451935_-	TIGR01250, Proline_iminopeptidase, proline-specific peptidase, Bacillus coagulans-type subfamily	NA|81aa|down_7|NZ_CP046309.1_3452210_3452453_+	NA	NA|431aa|down_8|NZ_CP046309.1_3452729_3454022_+	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily	NA|335aa|down_9|NZ_CP046309.1_3454005_3455010_+	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	14	3706154-3706262	8	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	GACAGCCAGCCGGCTGACCCGCCGT	25	0	0	NA	NA	NA	1	1	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA,NA	NA|544aa|up_9|NZ_CP046309.1_3695473_3697105_+	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles	NA|355aa|up_8|NZ_CP046309.1_3697180_3698245_+	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]	NA|158aa|up_7|NZ_CP046309.1_3698297_3698771_+	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins	NA|288aa|up_6|NZ_CP046309.1_3698804_3699668_+	cd01908, YafJ, Glutamine amidotransferases class-II (Gn-AT)_YafJ-type	NA|286aa|up_5|NZ_CP046309.1_3699672_3700530_+	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]	NA|361aa|up_4|NZ_CP046309.1_3700530_3701613_-	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6	NA|140aa|up_3|NZ_CP046309.1_3701693_3702113_-	pfam17301, LpqV, Putative lipoprotein LpqV	NA|189aa|up_2|NZ_CP046309.1_3702224_3702791_+	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain	NA|132aa|up_1|NZ_CP046309.1_3702787_3703183_+	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain	NA|672aa|up_0|NZ_CP046309.1_3703210_3705226_-	pfam00934, PE, PE family	NA|588aa|down_0|NZ_CP046309.1_3707530_3709294_-	COG4425, COG4425, Predicted membrane protein [Function unknown]	NA|258aa|down_1|NZ_CP046309.1_3709290_3710064_-	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional	NA|346aa|down_2|NZ_CP046309.1_3710075_3711113_-	PRK05617, PRK05617, 3-hydroxyisobutyryl-CoA hydrolase; Provisional	NA|279aa|down_3|NZ_CP046309.1_3711299_3712136_+	COG4760, COG4760, Predicted membrane protein [Function unknown]	NA|284aa|down_4|NZ_CP046309.1_3712251_3713103_+	pfam18741, MTES_1575, REase_MTES_1575	NA|406aa|down_5|NZ_CP046309.1_3713176_3714394_-	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase	NA|315aa|down_6|NZ_CP046309.1_3714446_3715391_-	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases	NA|356aa|down_7|NZ_CP046309.1_3715613_3716681_+	COG0657, Aes, Esterase/lipase [Lipid metabolism]	NA|465aa|down_8|NZ_CP046309.1_3716737_3718132_+	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase	NA|241aa|down_9|NZ_CP046309.1_3718333_3719056_+	pfam06271, RDD, RDD family
GCF_009730235.1_ASM973023v1	NZ_CP046309	Mycobacterium tuberculosis strain FDAARGOS_750 chromosome, complete genome	15	4090074-4091146	9	CRISPRCasFinder	no		csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	Orphan	CCGCCGTTGCCGCCGGCACCGCCGTCGCCGAT	32	1	1	4090274-4090295	NZ_CP046309.1_3727084-3727063	NA	15	15	Orphan	csa3,WYL,cas4,DEDDh,c2c9_V-U4,cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6,cas3,RT,DinG	NA|106aa|up_7|NZ_CP046309.1_4081837_4082155_+,NA	NA|103aa|up_9|NZ_CP046309.1_4079352_4079661_+	pfam00934, PE, PE family	NA|540aa|up_8|NZ_CP046309.1_4079657_4081277_+	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion]	NA|106aa|up_7|NZ_CP046309.1_4081837_4082155_+	NA	NA|209aa|up_6|NZ_CP046309.1_4082289_4082916_+	PRK00300, gmk, guanylate kinase; Provisional	NA|111aa|up_5|NZ_CP046309.1_4082981_4083314_+	TIGR00690, DNA-directed_RNA_polymerase_subunit_omega, DNA-directed RNA polymerase, omega subunit	NA|419aa|up_4|NZ_CP046309.1_4083329_4084586_+	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated	NA|404aa|up_3|NZ_CP046309.1_4084713_4085925_+	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated	NA|493aa|up_2|NZ_CP046309.1_4085997_4087476_-	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]	NA|462aa|up_1|NZ_CP046309.1_4087472_4088858_-	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]	NA|345aa|up_0|NZ_CP046309.1_4088935_4089970_+	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein	NA|134aa|down_0|NZ_CP046309.1_4092000_4092402_-	cd18741, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily	NA|86aa|down_1|NZ_CP046309.1_4092398_4092656_-	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family	NA|320aa|down_2|NZ_CP046309.1_4092738_4093698_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|321aa|down_3|NZ_CP046309.1_4093722_4094685_-	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold	NA|201aa|down_4|NZ_CP046309.1_4094818_4095421_+	COG3714, COG3714, Predicted membrane protein [Function unknown]	NA|656aa|down_5|NZ_CP046309.1_4095501_4097469_+	PRK14873, PRK14873, primosomal protein N'	NA|275aa|down_6|NZ_CP046309.1_4097486_4098311_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|161aa|down_7|NZ_CP046309.1_4098479_4098962_+	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein	NA|275aa|down_8|NZ_CP046309.1_4099033_4099858_-	pfam13649, Methyltransf_25, Methyltransferase domain	NA|313aa|down_9|NZ_CP046309.1_4100054_4100993_+	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed
