NCBI Pathogen Detection (https://www.ncbi.nlm.nih.gov/pathogens/isolates/) integrates bacterial pathogen genomic sequences originating in food, environmental sources, and patients. 368 clinical isolates (31 species) from human submitted in 2020, which have complete bacterial genome sequences and predicted AMR genotypes were collected for infecting phages prediction using PHISDetector. Finally, reliable infecting phages for 315 bacterial isolates (85.6%) from 21 species (67.7%) were obtained. View the result tables.

454 bacteria isolates from human gastrointestinal tract that have completed sequencing and annotation were collected from https://www.hmpdacc.org/hmp/HMRGD/. Candidate phages for 135 bacteria from 55 species were predicted using PHISDetector with high reliability. These interactions provided potential tools for precise manipulation of specific microbes in human gut, benefit for studying the function of intestinal symbiotic bacteria or developing therapies for treating pathogenic bacteria. View the result tables.

Antibiotic resistance in human pathogenic bacteria has been becoming a threat to public health in the recent years, phage therapy is one of the alternatives to antibiotics. This case demonstrates the result of analysis about the two phage cocktail used as phage therapy. Data of Georgian Bacteriophage Cocktail was analysed based on the Similarity analysis. HostPhinder and GeneNet are used for identifying the bacteria host of those bacteriophage in Georgian Bacteriophage Cocktail. All the bacteria hosts except for Streptococcus are predicted on the basis of genus level. View the result tables.

3641 bacterial genomes with prophage regions were collected and those prophage regions are identified by PHASTER, VirSorter and Prophinder respectively, those data are available for download in our website. We process the prophage region futher to obtain an integrated file containing prophage region information, the processing criterion for each bacteria is as follows:(1) Retain one prophage region if multiple methods identify the same prophage region, but the method for identifying are all reserved. (2) Merge prophage region if there exists overlap between regions of the prophage identified by multiple methods. View the result tables.

755 phages with annotated hosts are analyzed for identifying the protein interaction between bacteriophage and bacteria host. Those interaction information are critical to the study of effective infection of host cells. View the result tables.