CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
FNEC01000038	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1038, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000008	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1008, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
FNEC01000095	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1095, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000090	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1090, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000080	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1080, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000064	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1064, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000006	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1006, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
FNEC01000042	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1042, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000083	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1083, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000012	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1012, whole genome shotgun sequence	0 crisprs	DinG,csa3	0	0	0	0
FNEC01000053	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1053, whole genome shotgun sequence	0 crisprs	NA	0	0	1	1
FNEC01000079	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1079, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000011	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1011, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000029	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1029, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000045	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1045, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000017	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1017, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
FNEC01000028	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1028, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000070	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1070, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000098	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1098, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000002	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1002, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000078	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1078, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000047	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1047, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
FNEC01000086	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1086, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000067	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1067, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000026	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1026, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
FNEC01000077	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1077, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000014	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1014, whole genome shotgun sequence	0 crisprs	NA	0	0	2	0
FNEC01000087	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1087, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000050	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1050, whole genome shotgun sequence	0 crisprs	csa3	0	0	0	0
FNEC01000082	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1082, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000007	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1007, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000043	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1043, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000062	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1062, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000081	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1081, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000020	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1020, whole genome shotgun sequence	0 crisprs	cas3	0	0	0	0
FNEC01000044	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1044, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000004	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1004, whole genome shotgun sequence	0 crisprs	DEDDh,csa3	0	0	0	0
FNEC01000100	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1100, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000099	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1099, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000021	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1021, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000046	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1046, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000052	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1052, whole genome shotgun sequence	0 crisprs	cas3	0	0	0	0
FNEC01000009	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1009, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000060	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1060, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000096	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1096, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000024	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1024, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000040	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1040, whole genome shotgun sequence	0 crisprs	cas3	0	0	0	0
FNEC01000093	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1093, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000089	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1089, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000016	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1016, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000015	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1015, whole genome shotgun sequence	0 crisprs	csa3	0	0	0	0
FNEC01000039	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1039, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000097	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1097, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000033	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1033, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000037	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1037, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	1	3
FNEC01000094	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1094, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000018	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1018, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000066	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1066, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000074	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1074, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000068	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1068, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000034	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1034, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000055	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1055, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000027	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1027, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000030	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1030, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000084	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1084, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000023	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1023, whole genome shotgun sequence	1 crisprs	NA	1	3	0	0
FNEC01000073	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1073, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000019	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1019, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000005	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1005, whole genome shotgun sequence	3 crisprs	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	1	10	0	0
FNEC01000036	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1036, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000022	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1022, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000076	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1076, whole genome shotgun sequence	0 crisprs	DinG	0	0	0	0
FNEC01000065	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1065, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000071	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1071, whole genome shotgun sequence	0 crisprs	RT	0	0	0	0
FNEC01000031	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1031, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
FNEC01000063	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1063, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000035	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000101	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1101, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000058	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1058, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000072	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1072, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000056	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1056, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000054	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1054, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000092	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1092, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000061	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1061, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000059	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1059, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000013	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1013, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000032	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1032, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000010	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1010, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
FNEC01000041	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1041, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000048	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1048, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000085	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1085, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000057	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1057, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000075	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1075, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000049	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1049, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000003	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1003, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000001	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1001, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000025	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1025, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
FNEC01000051	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1051, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000088	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1088, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000069	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1069, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
FNEC01000091	Pseudomonas delhiensis strain CCM 7361 genome assembly, contig: Ga0104656_1091, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6559 : 16553

Pseudomonas_phage(62.5%)

capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDK67850.1\|6559_7579_-\|capsid	phage major capsid protein, HK97 family	S4TNE3	Salmonella_phage	2.0e-30	32.0
SDK67882.1\|7936_8236_-	hypothetical protein	NA	NA	NA	NA
SDK67921.1\|8235_9774_-	Protein of unknown function	NA	NA	NA	NA
SDK67955.1\|9766_10645_-	putative DNA primase/helicase	A0A1B0VML8	Pseudomonas_phage	7.6e-95	65.6
SDK67983.1\|10641_10860_-	hypothetical protein	A0A1B0VRK9	Pseudomonas_phage	1.2e-22	68.0
SDK68021.1\|10852_11134_-	hypothetical protein	A0A1B0VMJ4	Pseudomonas_phage	4.2e-23	64.7
SDK68056.1\|11139_11685_-	hypothetical protein	A0A0A0YUG0	Pseudomonas_phage	1.9e-11	34.0
SDK68093.1\|11932_12091_-	hypothetical protein	NA	NA	NA	NA
SDK68133.1\|12083_12317_-	hypothetical protein	NA	NA	NA	NA
SDK68176.1\|12309_12573_-	hypothetical protein	NA	NA	NA	NA
SDK68218.1\|12851_13061_-	transcriptional regulator, AlpA family	B7SYF9	Stenotrophomonas_phage	1.3e-08	50.0
SDK68256.1\|13143_13647_-	hypothetical protein	NA	NA	NA	NA
SDK68288.1\|13643_14855_-	Integrase	A0A1B0VMI6	Pseudomonas_phage	1.3e-166	71.2
SDK68327.1\|15216_15489_-	Fe-S cluster biosynthesis and repair protein YggX	NA	NA	NA	NA
SDK68366.1\|15485_16553_-	A/G-specific DNA-adenine glycosylase	G3CB03	Aeropyrum_pernix_spindle-shaped_virus	3.4e-28	32.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. FNEC01000010

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

33743 : 39996

Powai_lake_megavirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDI89997.1\|33743_34175_-	nucleoside diphosphate kinase	A0A167REB2	Powai_lake_megavirus	1.2e-21	41.7
SDI90034.1\|34499_34700_-	FeS assembly protein IscX	NA	NA	NA	NA
SDI90069.1\|34713_35052_-	ferredoxin, 2Fe-2S	NA	NA	NA	NA
SDI90101.1\|35058_36918_-	Chaperone protein HscA	F2Y2E1	Organic_Lake_phycodnavirus	1.6e-105	40.3
SDI90147.1\|36963_37485_-	Co-chaperone protein HscB	NA	NA	NA	NA
SDI90184.1\|37492_37816_-	Iron-binding apoprotein IscA	A0A2H4N7N5	Lake_Baikal_phage	2.2e-23	49.5
SDI90219.1\|37842_38229_-	FeS assembly scaffold apoprotein IscU	A0A218MKD1	uncultured_virus	1.6e-52	79.8
SDI90257.1\|38255_39470_-	cysteine desulfurase IscS	H7BUW1	unidentified_phage	7.2e-35	39.8
SDI90297.1\|39498_39996_-	transcriptional regulator, BadM/Rrf2 family	M4M9K8	Vibrio_phage	3.7e-06	29.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. FNEC01000001

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. FNEC01000037

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

114 : 34736

Pseudomonas_phage(28.57%)

terminase,head,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDK39374.1\|114_855_-	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	A0A2H4J6Q0	uncultured_Caudovirales_phage	1.2e-27	41.1
SDK39414.1\|934_1198_+	hypothetical protein	A0A2H4J0V8	uncultured_Caudovirales_phage	3.1e-12	55.4
SDK39458.1\|1207_1396_+	hypothetical protein	NA	NA	NA	NA
SDK39501.1\|1358_1568_-	hypothetical protein	NA	NA	NA	NA
SDK39536.1\|1664_1853_+	hypothetical protein	B5WZX7	Pseudomonas_phage	2.1e-26	100.0
SDK39579.1\|1871_2051_+	hypothetical protein	B5WZX8	Pseudomonas_phage	1.5e-21	86.4
SDK39618.1\|2137_2968_+	hypothetical protein	A0A2H4J580	uncultured_Caudovirales_phage	5.0e-64	48.4
SDK39659.1\|2957_3749_+	phage DNA replication protein (predicted replicative helicase loader)	A0A059VK34	Pseudomonas_phage	1.6e-67	58.3
SDK39695.1\|3894_4014_+	hypothetical protein	Q9MC53	Pseudomonas_phage	8.8e-07	63.2
SDK39722.1\|4013_4184_+	hypothetical protein	NA	NA	NA	NA
SDK39759.1\|4176_4452_+	hypothetical protein	NA	NA	NA	NA
SDK39794.1\|4444_4849_+	NinB protein	A0A059VG13	Pseudomonas_phage	5.3e-35	55.1
SDK39835.1\|5028_5148_+	hypothetical protein	NA	NA	NA	NA
SDK39872.1\|5272_5875_+	Bacteriophage Lambda NinG protein	A0A125RNK9	Pseudomonas_phage	6.6e-90	84.0
SDK39909.1\|5871_6462_+	hypothetical protein	A0A0S2SYA9	Pseudomonas_phage	3.6e-56	51.8
SDK39949.1\|6582_6891_+	hypothetical protein	A0A125RNL3	Pseudomonas_phage	5.0e-17	54.1
SDK39988.1\|6893_7196_+	hypothetical protein	A0A125RNL4	Pseudomonas_phage	1.5e-21	58.9
SDK40041.1\|7208_7523_+	hypothetical protein	NA	NA	NA	NA
SDK40079.1\|7482_8883_+\|terminase	phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	1.2e-169	63.6
SDK40116.1\|8879_10379_+	hypothetical protein	A0A2R3UAL5	Myoviridae_environmental_samples	2.7e-116	48.3
SDK40155.1\|10431_11115_+\|head	phage putative head morphogenesis protein, SPP1 gp7 family	H9C0V1	Aeromonas_phage	7.3e-61	52.2
SDK40199.1\|11265_12762_+	hypothetical protein	A0A219YBB9	Aeromonas_phage	7.4e-66	38.5
SDK40235.1\|12766_13246_+	hypothetical protein	A0A219YBF2	Aeromonas_phage	3.9e-37	56.3
SDK40288.1\|13248_14286_+	hypothetical protein	A0A219YBB0	Aeromonas_phage	1.1e-92	51.6
SDK40340.1\|14289_14616_+	hypothetical protein	A0A1V0DZF2	Acinetobacter_phage	4.9e-07	37.9
SDK40379.1\|14619_15054_+	Protein of unknown function	A0A1X9SF97	Acinetobacter_phage	3.5e-16	39.4
SDK40422.1\|15041_15515_+	hypothetical protein	A0A077KC03	Edwardsiella_phage	2.2e-24	48.1
SDK40461.1\|15492_15873_+	hypothetical protein	A0A077KAW7	Edwardsiella_phage	1.8e-21	41.6
SDK40499.1\|15851_16445_+	hypothetical protein	H9C0W4	Aeromonas_phage	2.4e-15	31.2
SDK40540.1\|16569_17862_+	Protein of unknown function	H9C0W5	Aeromonas_phage	2.1e-69	38.3
SDK40577.1\|17874_18306_+	hypothetical protein	H9C0W6	Aeromonas_phage	5.9e-24	44.5
SDK40617.1\|18305_18734_+	hypothetical protein	H9C0W7	Aeromonas_phage	9.6e-19	44.6
SDK40661.1\|18913_20794_+	hypothetical protein	A0A1W6JPF2	Morganella_phage	6.8e-24	27.5
SDK40712.1\|20793_21441_+	hypothetical protein	A0A1X9SFH6	Acinetobacter_phage	4.4e-23	36.0
SDK40756.1\|21449_22976_+	Putative Ig domain-containing protein	A0A1D8KTD3	Synechococcus_phage	2.0e-13	27.7
SDK40803.1\|23565_24447_+	hypothetical protein	A0A2R3UAK8	Myoviridae_environmental_samples	6.4e-33	30.3
SDK40853.1\|24430_25087_+	hypothetical protein	A0A2R3UAK1	Myoviridae_environmental_samples	2.1e-33	46.9
SDK40896.1\|25035_25653_-	hypothetical protein	NA	NA	NA	NA
SDK40938.1\|25683_26037_+	hypothetical protein	A0A077KCA1	Edwardsiella_phage	5.7e-17	44.2
SDK40985.1\|26036_27251_+\|plate	Baseplate J-like protein	A0A2R3UAL9	Myoviridae_environmental_samples	1.2e-93	47.2
SDK41025.1\|27247_27928_+	Protein of unknown function	A0A2R3UAM9	Myoviridae_environmental_samples	2.8e-52	48.8
SDK41066.1\|27917_29021_+	hypothetical protein	Q6UIZ8	Burkholderia_virus	1.5e-23	48.5
SDK41101.1\|29267_30029_-	methyltransferase, FkbM family	I3UL74	Ostreococcus_lucimarinus_virus	3.7e-13	33.9
SDK41146.1\|30154_30688_+	putative chitinase	A0A059VA40	Pseudomonas_phage	7.9e-63	68.4
SDK41192.1\|30684_31194_+	Protein of unknown function	A0A077KH21	Edwardsiella_phage	1.7e-17	41.7
SDK41238.1\|31216_31456_-	hypothetical protein	W6MWY2	Pseudomonas_phage	4.5e-26	83.3
SDK41283.1\|31418_31715_-	hypothetical protein	A0A0A1IW04	Pseudomonas_phage	8.4e-22	46.9
SDK41332.1\|31716_31917_-	hypothetical protein	A0SMP0	Pseudomonas_virus	5.5e-25	85.9
SDK41378.1\|31964_32147_-	hypothetical protein	NA	NA	NA	NA
SDK41423.1\|32642_34736_+	Anaerobic selenocysteine-containing dehydrogenase	A0A077SK27	Escherichia_phage	1.4e-22	26.1

Anti-CRISPR protein detection

Acr_ID: FNEC01000037.1|SDK41283.1|31418_31715_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: FNEC01000037.1|SDK41332.1|31716_31917_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: FNEC01000037.1|SDK41378.1|31964_32147_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

FNEC01000037.1|SDK41283.1|31418_31715_-|hypothetical-protein

31418_31715_-

98 aa aa

AcrIF4

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR0002\|YP_007392799.1\|AcrIF4\|I-F\|Verified\|Pseudomonas-phage-JBD24	0.46938775510204084	1.0	0.98

FNEC01000037.1_31216_31456_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
FNEC01000037.1_31216_31456_-	AcrIE7-Aca1\|WP_087937213.1	0.8484848484848485	0.8481012658227848	0.9428571428571428

114-34736

FNEC01000037.1|SDK41332.1|31716_31917_-|hypothetical-protein

31716_31917_-

66 aa aa

AcrIE3

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR0408\|YP_950454.1\|AcrIE3\|I-E\|Verified\|Pseudomonas-phage-DMS3	0.859375	0.9848484848484849	0.9411764705882353

FNEC01000037.1_31216_31456_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
FNEC01000037.1_31216_31456_-	AcrIE7-Aca1\|WP_087937213.1	0.8484848484848485	0.8481012658227848	0.9428571428571428

114-34736

FNEC01000037.1|SDK41378.1|31964_32147_-|hypothetical-protein

31964_32147_-

60 aa aa

AcrIC5

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3672\|SDK41378.1\|AcrIC5\|I-C\|Verified\|Pseudomonas-delhiensis	1.0	1	1.0

FNEC01000037.1_31216_31456_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
FNEC01000037.1_31216_31456_-	AcrIE7-Aca1\|WP_087937213.1	0.8484848484848485	0.8481012658227848	0.9428571428571428

114-34736

5. FNEC01000017

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

20915 : 27944

Ectocarpus_siliculosus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDJ44029.1\|20915_22193_-	Signal transduction histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	1.8e-07	22.4
SDJ44067.1\|22182_22866_-	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	W8CYM9	Bacillus_phage	6.7e-30	34.1
SDJ44109.1\|23049_23433_-	camphor resistance protein CrcB	A0A2H4J148	uncultured_Caudovirales_phage	2.7e-36	68.0
SDJ44151.1\|23634_25275_-	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	3.9e-177	64.7
SDJ44192.1\|25323_25617_-	chaperonin GroES	A0A221S4G8	uncultured_virus	3.7e-14	48.4
SDJ44234.1\|25809_26277_-	UPF0716 protein FxsA	NA	NA	NA	NA
SDJ44268.1\|26341_27079_-	hypothetical protein	NA	NA	NA	NA
SDJ44308.1\|27185_27944_+	3-oxoacyl-[acyl-carrier protein] reductase	A0A0N9R355	Chrysochromulina_ericina_virus	5.9e-11	28.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. FNEC01000053

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

29609 : 40490

Pseudomonas_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDK82218.1\|29609_30683_-	iron(III) transport system ATP-binding protein	Q6GZ03	Mycoplasma_phage	7.5e-20	30.7
SDK82250.1\|30811_31729_-	ornithine carbamoyltransferase	NA	NA	NA	NA
SDK82293.1\|32268_32943_+	hypothetical protein	NA	NA	NA	NA
SDK82344.1\|32927_33266_-	hypothetical protein	A0A0H5ARD3	Pseudomonas_phage	4.5e-19	50.0
SDK82387.1\|33474_33909_-	hypothetical protein	W6MW33	Pseudomonas_phage	2.5e-06	36.6
SDK82432.1\|34105_34381_-	hypothetical protein	A0A127KNQ8	Pseudomonas_phage	5.2e-18	53.2
SDK82476.1\|34421_34673_-	hypothetical protein	Q9MC80	Pseudomonas_phage	1.7e-15	62.9
SDK82523.1\|34665_35148_-	hypothetical protein	A0A0N7IRF6	Acinetobacter_phage	7.7e-57	62.4
SDK82557.1\|35128_35797_-	hypothetical protein	NA	NA	NA	NA
SDK82600.1\|36277_37108_-	hypothetical protein	A0A0U1UNM2	Pseudomonas_phage	1.9e-23	61.5
SDK82651.1\|37104_37323_-	hypothetical protein	NA	NA	NA	NA
SDK82687.1\|37409_37670_+	hypothetical protein	NA	NA	NA	NA
SDK82708.1\|37663_38809_-	DNA (cytosine-5)-methyltransferase 1	Q6V7R9	Burkholderia_virus	6.5e-86	50.0
SDK82742.1\|39027_39390_-	hypothetical protein	A0A125RNR1	Pseudomonas_phage	6.4e-32	66.0
SDK82802.1\|39386_40490_-	AAA domain-containing protein	I6PCV5	Cronobacter_phage	1.0e-152	71.0

Anti-CRISPR protein detection

Acr_ID: FNEC01000053.1|SDK82432.1|34105_34381_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

FNEC01000053.1|SDK82432.1|34105_34381_-|hypothetical-protein

34105_34381_-

91 aa aa

29609-40490

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
FNEC01000023_1	Orphan	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	38419-38388	2

1. spacer 1.5|12735|32|FNEC01000023|CRT matches to FNEC01000053 position: 38419-38388, mismatch: 2

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
caacgacgccgccgtgtgttcgttgtcgcaag	Protospacer
*********************.*.********

7. FNEC01000031

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

19467 : 25457

uncultured_Caudovirales_phage(75.0%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDK18569.1\|19467_20469_-	Anthranilate phosphoribosyltransferase	A0A2H4JBY5	uncultured_Caudovirales_phage	3.6e-141	74.6
SDK18614.1\|20465_20801_-\|tRNA	tRNA 2-thiouridine synthesizing protein E	A0A2H4J8B6	uncultured_Caudovirales_phage	1.0e-39	72.1
SDK18669.1\|20797_21097_-\|tRNA	tRNA 2-thiouridine synthesizing protein B	A0A2H4JG28	uncultured_Caudovirales_phage	2.5e-21	58.8
SDK18710.1\|21096_21456_-\|tRNA	tRNA 2-thiouridine synthesizing protein C	A0A2H4J8C0	uncultured_Caudovirales_phage	1.8e-34	64.2
SDK18773.1\|21455_21848_-\|tRNA	tRNA 2-thiouridine synthesizing protein D	A0A2H4JA39	uncultured_Caudovirales_phage	1.8e-51	76.7
SDK18810.1\|21963_22629_-\|protease	modulator of FtsH protease	A0A2H4JFM9	uncultured_Caudovirales_phage	8.3e-86	77.6
SDK18865.1\|23514_24528_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	4.6e-43	31.7
SDK18895.1\|24524_25457_-	acetaldehyde dehydrogenase	G8DDL4	Micromonas_pusilla_virus	2.1e-34	34.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. FNEC01000023

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: FNEC01000023_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

FNEC01000023_1

12585-12794

Orphan

I-F

Consensus_repeat	Method
ATACTTCACTGCCGTGTAGGCAGCTAAGAAA	PILER-CR
CTTCACTGCCGTGTAGGCAGCTAAGAAA	CRT

3 spacers

The CRISPR arrays of FNEC01000023_1

>merge|FNEC01000023|1|12585-12794|PILER-CR,CRT
TACTTCACTGCCGTGTAGGCAGCTAAGAAAAGATGGAGCGCTATGCGGCGCGCTTGAACAAACTTCACTGCCGTGTAGGCAGCTAAGAAATGGAGGTAAGCGCCTCCGGGAAGCTTGTAATTCTTCACTGCCGTGTAGGCAGCTGAGAAACAACGACGCCGCCGTGTGTTCATCGTCGCAAGCTTCACTGCCATACAGGCAGACAGTGCT

>FNEC01000023|1|1|12585-12734|PILER-CR
TACTTCACTGCCGTGTAGGCAGCTAAGAAAA	GATGGAGCGCTATGCGGCGCGCTTGAACA
AACTTCACTGCCGTGTAGGCAGCTAAGAAAT	GGAGGTAAGCGCCTCCGGGAAGCTTGTAA
TTCTTCACTGCCGTGTAGGCAGCTGAGAAA

>FNEC01000023|1|1|12587-12794|CRT
CTTCACTGCCGTGTAGGCAGCTAAGAAA	AGATGGAGCGCTATGCGGCGCGCTTGAACAAA
CTTCACTGCCGTGTAGGCAGCTAAGAAA	TGGAGGTAAGCGCCTCCGGGAAGCTTGTAATT
CTTCACTGCCGTGTAGGCAGCTGAGAAA	CAACGACGCCGCCGTGTGTTCATCGTCGCAAG
CTTCACTGCCATACAGGCAGACAGTGCT

Protein	Signature genes	Signature genes Name	Protein_function
FNEC01000023.1\|SDJ78607.1\|6482_7586_+\|transcriptional-regulator,-AraC-family-with-amidase-like-domain	unknown	unknown	gnl\|CDD\|227311
FNEC01000023.1\|SDJ78518.1\|3483_4410_-\|glycine-betaine/proline-transport-system-substrate-binding-protein	unknown	unknown	gnl\|CDD\|188316
FNEC01000023.1\|SDJ79123.1\|23148_23787_-\|hypothetical-protein	unknown	unknown	unknown
FNEC01000023.1\|SDJ78756.1\|9540_11535_-\|Serine-phosphatase-RsbU,-regulator-of-sigma-subunit	unknown	unknown	gnl\|CDD\|225118
FNEC01000023.1\|SDJ78796.1\|11721_12372_-\|phosphoglycolate-phosphatase	unknown	unknown	gnl\|CDD\|319798
FNEC01000023.1\|SDJ78473.1\|2324_3263_-\|glycine-betaine/proline-transport-system-substrate-binding-protein	unknown	unknown	gnl\|CDD\|188316
FNEC01000023.1\|SDJ78440.1\|1443_2283_-\|glycine-betaine/proline-transport-system-permease-protein	unknown	unknown	gnl\|CDD\|188318
FNEC01000023.1\|SDJ78994.1\|18815_20441_+\|inorganic-phosphate-transporter,-PiT-family	unknown	unknown	gnl\|CDD\|223383
FNEC01000023.1\|SDJ78719.1\|8988_9531_-\|hypothetical-protein	unknown	unknown	unknown
FNEC01000023.1\|SDJ78643.1\|7780_8578_-\|diguanylate-cyclase-(GGDEF)-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
FNEC01000023.1\|SDJ79214.1\|25297_26893_+\|cytochrome-c-oxidase-subunit-1	unknown	unknown	gnl\|CDD\|238833
FNEC01000023.1\|SDJ78681.1\|8582_8963_-\|protein-of-unknown-function	unknown	unknown	gnl\|CDD\|378154
FNEC01000023.1\|SDJ78953.1\|16027_18538_-\|diguanylate-cyclase/phosphodiesterase-with-PAS/PAC-sensor(s)	unknown	unknown	gnl\|CDD\|183097
FNEC01000023.1\|SDJ79161.1\|24159_25284_+\|cytochrome-c-oxidase-subunit-2	unknown	unknown	gnl\|CDD\|224537
FNEC01000023.1\|SDJ79039.1\|20885_21947_+\|DNA-repair-photolyase	unknown	unknown	gnl\|CDD\|275263
FNEC01000023.1\|SDJ78563.1\|4740_6117_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
FNEC01000023.1\|SDJ78913.1\|15475_15742_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312883
FNEC01000023.1\|SDJ78872.1\|13430_15476_+\|oligopeptidase-A-Metallo-peptidase.-MEROPS-family-M03A	unknown	unknown	gnl\|CDD\|341051
FNEC01000023.1\|SDJ79077.1\|22189_22903_+\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|238449
FNEC01000023.1\|SDJ78834.1\|12809_13352_-\|Carbonic-anhydrase-or-acetyltransferase,-isoleucine-patch-superfamily	unknown	unknown	gnl\|CDD\|100051

Protein	Function_ID	Function_description	E-value
FNEC01000023.1\|SDJ78607.1\|6482_7586_+\|transcriptional-regulator,-AraC-family-with-amidase-like-domain	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	9.32284e-146
FNEC01000023.1\|SDJ78518.1\|3483_4410_-\|glycine-betaine/proline-transport-system-substrate-binding-protein	gnl\|CDD\|188316	TIGR03414, ABC_choline_bnd, choline ABC transporter, periplasmic binding protein. Partial phylogenetic profiling () vs. the genome property of glycine betaine biosynthesis from choline consistently reveals a member of this ABC transporter periplasmic binding protein as the best match, save for the betaine biosynthesis enzymes themselves. Genomes often carry several paralogs, one encoded together with the permease and ATP-binding components and another encoded next to a choline-sulfatase gene, suggesting that different members of this protein family interact with shared components and give some flexibility in substrate. Of two members from Sinorhizobium meliloti 1021, one designated ChoX has been shown experimentally to bind choline (though not various related compounds such as betaine) and to be required for about 60 % of choline uptake. Members of this protein have an invariant Cys residue near the N-terminus and likely are lipoproteins. [Transport and binding proteins, Amino acids, peptides and amines].	1.54702e-174
FNEC01000023.1\|SDJ79214.1\|25297_26893_+\|cytochrome-c-oxidase-subunit-1	gnl\|CDD\|238833	cd01663, Cyt_c_Oxidase_I, Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of prokaryotes. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits varies from three to five in bacteria and up to 13 in mammalian mitochondria. Only subunits I and II are essential for function, but subunit III, which is also conserved, may play a role in assembly or oxygen delivery to the active site. Subunits I, II, and III of mammalian CcO are encoded within the mitochondrial genome and the remaining 10 subunits are encoded within the nuclear genome. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme (heme a3) and a copper ion (CuB). It also contains a low-spin heme (heme a), believed to participate in the transfer of electrons to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from cytochrome c on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are transferred from cytochrome c (the electron donor) to heme a via the CuA binuclear site in subunit II, and directly from heme a to the binuclear center.	0
FNEC01000023.1\|SDJ78756.1\|9540_11535_-\|Serine-phosphatase-RsbU,-regulator-of-sigma-subunit	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	2.2567e-45
FNEC01000023.1\|SDJ78796.1\|11721_12372_-\|phosphoglycolate-phosphatase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.19773e-100
FNEC01000023.1\|SDJ78473.1\|2324_3263_-\|glycine-betaine/proline-transport-system-substrate-binding-protein	gnl\|CDD\|188316	TIGR03414, ABC_choline_bnd, choline ABC transporter, periplasmic binding protein. Partial phylogenetic profiling () vs. the genome property of glycine betaine biosynthesis from choline consistently reveals a member of this ABC transporter periplasmic binding protein as the best match, save for the betaine biosynthesis enzymes themselves. Genomes often carry several paralogs, one encoded together with the permease and ATP-binding components and another encoded next to a choline-sulfatase gene, suggesting that different members of this protein family interact with shared components and give some flexibility in substrate. Of two members from Sinorhizobium meliloti 1021, one designated ChoX has been shown experimentally to bind choline (though not various related compounds such as betaine) and to be required for about 60 % of choline uptake. Members of this protein have an invariant Cys residue near the N-terminus and likely are lipoproteins. [Transport and binding proteins, Amino acids, peptides and amines].	0
FNEC01000023.1\|SDJ78440.1\|1443_2283_-\|glycine-betaine/proline-transport-system-permease-protein	gnl\|CDD\|188318	TIGR03416, ABC_choXWV_perm, choline ABC transporter, permease protein.	2.37553e-142
FNEC01000023.1\|SDJ78994.1\|18815_20441_+\|inorganic-phosphate-transporter,-PiT-family	gnl\|CDD\|223383	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism].	7.80365e-55
FNEC01000023.1\|SDJ78643.1\|7780_8578_-\|diguanylate-cyclase-(GGDEF)-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.31008e-62
FNEC01000023.1\|SDJ78681.1\|8582_8963_-\|protein-of-unknown-function	gnl\|CDD\|378154	pfam09345, DUF1987, Domain of unknown function (DUF1987). This family of proteins are functionally uncharacterized.	6.68367e-54
FNEC01000023.1\|SDJ78953.1\|16027_18538_-\|diguanylate-cyclase/phosphodiesterase-with-PAS/PAC-sensor(s)	gnl\|CDD\|183097	PRK11359, PRK11359, cyclic-di-GMP phosphodiesterase; Provisional.	0
FNEC01000023.1\|SDJ79161.1\|24159_25284_+\|cytochrome-c-oxidase-subunit-2	gnl\|CDD\|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	2.92411e-75
FNEC01000023.1\|SDJ79039.1\|20885_21947_+\|DNA-repair-photolyase	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	1.1909e-23
FNEC01000023.1\|SDJ78563.1\|4740_6117_+\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
FNEC01000023.1\|SDJ78913.1\|15475_15742_+\|hypothetical-protein	gnl\|CDD\|312883	pfam09526, DUF2387, Probable metal-binding protein (DUF2387). Members of this family are small proteins, about 70 residues in length, with a basic triplet near the N-terminus and a probable metal-binding motif CPXCX(18)CXXC. Members are found in various proteobacteria.	1.17633e-39
FNEC01000023.1\|SDJ78872.1\|13430_15476_+\|oligopeptidase-A-Metallo-peptidase.-MEROPS-family-M03A	gnl\|CDD\|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
FNEC01000023.1\|SDJ79077.1\|22189_22903_+\|carbonic-anhydrase	gnl\|CDD\|238449	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	3.05184e-98
FNEC01000023.1\|SDJ78834.1\|12809_13352_-\|Carbonic-anhydrase-or-acetyltransferase,-isoleucine-patch-superfamily	gnl\|CDD\|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	1.88682e-80

>FNEC01000023.1|SDJ78796.1|11721_12372_-|phosphoglycolate-phosphatase
MHYQNILFDLDGTLTDPREGITRSIQYALAQLGIDEPDLRRLEHFIGPPLLQCFMSTYGFDEARAWEAVNHYRVRFKDTGLYENRVFEGVGELLELLGGQGRTLYIATSKPTVFAAEIARHFDFARHFRVIYGSELDGTRTNKVELIEHLLRLEGLDPAQTLMIGDRKHDLVGAHRNGLSAAGVGYGFGSREELLAEGPAHYFASLDELRAAFAAS
>FNEC01000023.1|SDJ78756.1|9540_11535_-|Serine-phosphatase-RsbU,-regulator-of-sigma-subunit
MAARWGLRGKSVVALLLACVLALVPAVLLGWKAMEDIRTHFGLAYAKNFTLLNQQKILAPVIRELSLSRRLAESVVTQDWLLEEGNSERRTRFFREADGYRGDQGEYSYFVIVDSSLHYYFNDSTSPLSNAPRYTLSRDDPQDAWYFATMASDSPYNINVNYDAKLRATKVWFNVQVIAGNHKVGLAGGGLDLTAFLDQFISRREAGVTPMIVDADGAIQAHPDRKLIALSSGAGTAESGGHRVFDLLASDEERKGLRQVLDDAQAHPGEVRTFWATLDGKQQLLATAYIPELRWHVLSAVDLHAAQVLDSRWIWPLAGTLAGLLALLLLGFAYTVELLLLKPLRGLRQSAKAIAAGQYDNPLPKSRGDEIGELSEAFASMAEQVRRHTEDLEDKVRQRTQALEQANREMAAAQKKIGDSIDYASLLQRAILPDRQLQASLGQHHFVLWKPRDVVGGDFYIYREGSEDSLIGVVDCAGHGVPGALMTMLALAAIDHAIDSVQSHDPAAILRETDQVMRGMISQERVTQALATNMDAGFVRVDHGRRLLHFSGAKISLFASNGDEVREYKGGRRAIGDKRQGEYENIQLPLEPGWTFYLCTDGFLDQAGGEHGFGFGNSRFAELLRRHSRLPLAEQARVFAATLADYQGERPQRDDITILSFRFE
>FNEC01000023.1|SDJ78719.1|8988_9531_-|hypothetical-protein
METLDLLAMRESYTRQRILLCFNGPISRSLIEEIGHALRNYMQAEQAHPSEAMDVFAVYIEMTQNIRHYATQRGYGDLDASATVAIARNEDGHYVVSAGNLVELADGRELVRSIEDIAGLDKAQLKAAYKEQLRRPREAGASSGAGLGLLDIARKSSAPLQTSLTEQPDGRAFFSLRAVI
>FNEC01000023.1|SDJ78681.1|8582_8963_-|protein-of-unknown-function
MSDLHISGTQSTPSIHGDWDAGVLAMQGDSYPENSYELFGQVIEWVQRFLAEAQRPLSLDLRLLYLNTSSIKAMMDIFDLLEEAHAGGRQTQVSWHYDRRNERVAELAEEFREDCSFPFVIQPYDE
>FNEC01000023.1|SDJ78643.1|7780_8578_-|diguanylate-cyclase-(GGDEF)-domain-containing-protein
MNSERELDLLIEELLADPQYLDHPLREALFLKHQQSLDQLARLERIARISDGFQSMARAQNSTLSERYHKQLRQLEKVARISDRYQNMMRDLNVALREASTHDPLTGIGNRRLLMERLREESERAQRHGKPYVLVILDIDHFKQVNDTWGHEVGDRVLVEIGCTMQAALRQYDLCGRWGGEEFLLLLPETALADAGQVIDRVRQDIRSLAVRVGTEALSVTASFGVAEYRLGESYSQTLSRADAALLEAKRSGRDKCVASAVASG
>FNEC01000023.1|SDJ78607.1|6482_7586_+|transcriptional-regulator,-AraC-family-with-amidase-like-domain
MSAFNTGVPPQNRAPQSIGFLLLDNFTLISLASAVEPLRMANQLSGRELYRWHTLTLDGRQVWASDGLQITPDASTDAAPPMDSLIVVGGVGIQRSVTRDHVVFLQTQARLGRRLGAVCTGSWALARAGLLDGYDCSVHWECLAAMQEAFPRVAMSTRLFSIDRNRYTSSGGTAPMDMMLHLIGREHGRELSAAISEMFIYERIRNEQDHQRVPLKHMLGTNQPKLQEIVALMEANLEEPIDLDELAVYVNVSRRQLERLFQKYLHCSPSRYYLKLRLIRARQLLKQTSMSIIEVASVCGFVSTPHFSKCYREYFGIPPRDERQGQPIGQPVMVMPIPQDLALMPHSSAISALSQAQGESTFASVRV
>FNEC01000023.1|SDJ78563.1|4740_6117_+|L-serine-ammonia-lyase
MAISVFDLFKIGIGPSSSHTVGPMRAAALFVGALRERQLLERVERIEVKLYGSLSATGVGHGTDRAVIMGLMGEWPDRIDPGQIAPRMAELLGSGELILAGERRIPFDWVRDMRLLEENLPYHPNAMSLAAYENGQELHADTYYSIGGGFVVDAEQAAAGSLDQDSTRLPYDFDSAAELLQLCRRHNLRVSELMLANERMWRSDTDTRDGLMRIWRAMQDCVNNGLKAEGILPGGLNVQRRAARLHRNLLEIGKPNVIGSTLSAMEWVNLYALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYYMRFNPDASEQDVVDFFLAAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEVLGASPEQVENAAEIGLEHNLGLTCDPVGGLVQVPCIERNAIAAVKAINAAQMALRGDGQHFISLDQAIRTMRDTGADMHDKYKETSRGGLAVSIIEC
>FNEC01000023.1|SDJ78518.1|3483_4410_-|glycine-betaine/proline-transport-system-substrate-binding-protein
MKCLLLSLLALPVLCSGLAQAAEPQSCLLVRFADVGWTDITVTTAVTRLVLSEQGYRTKVERLSVPDTYKAMAEKRIDVFLGNWMPSMAADIKPYADNGSVQTVRANLEGAKYTLAVPRYAYDAGLKSFADIAKFKEQLGGRIYGIEPGNDGNQLIRKMIADKAFGLGDFKLVESSEADMLASVRRAGALKQPIVFLGWEPHPMNTRLQMRYLEGGDAYFGPNYGGATVYTNVRAGYLDECPNVAQLLRNLKFDLAMENRLMDAVLNERSNPRQAAKDWLQANPQVRDAWLKGVQPRAQAPSKAVVQQ
>FNEC01000023.1|SDJ78473.1|2324_3263_-|glycine-betaine/proline-transport-system-substrate-binding-protein
MKGCKSLLLAVSLSAPLVVQAAEPESCGTVRFSDVGWTDITVTTATTRQVLESLGYTTKVNMLSVPVTYRSLANKDLDVFLGNWMPSMANDIKPYADNGSVETVRANLEGAKYTLAVTQAAYDGGLKNFADIARFSDKLGGKIYGIEPGNDGNRLVQGMIDKNRFDLGKFKLVESSEAGMLSQVGRADRRNQWIVFLGWEPHPMNTRFKMQYLQGGDDVFGPNYGGATIYTNVRKGYVQECPNVGKLLTNLTFTLDMENKLMDAVLNGGKKPEDAAKAWLKDHPELLDAWLAGVTTRDGKPALAAAKVAFAK
>FNEC01000023.1|SDJ78440.1|1443_2283_-|glycine-betaine/proline-transport-system-permease-protein
MFLTEHKIPLGEHIAAFVDWLTRHGSAVFDKISDVLEFLIHGVTGGLLWFHPLLLTAIMVGLVHFIQRSVGLTLFALASLLLILNLGYWQETMETLAQVIFATLVCVAIGVPLGILAAHKPWFYTALRPLLDLMQTVPTFVYLIPTLTLFGLGVVPGLISTVIFAIAAPIRLTCLGIQDVPAELMDAGKAFGCSRWQLLTRIELPHAMPSIGAGITQCIMLSLSMVVISALVGADGLGKPVVNALNTADISLGFEAGLAIVLLAILLDRVCKQRSLRGR
>FNEC01000023.1|SDJ78834.1|12809_13352_-|Carbonic-anhydrase-or-acetyltransferase,-isoleucine-patch-superfamily
MAIRSYQGKTPQLGERVFVDPSAVLIGDIEIGADSSVWPLVTVRGDMHRIRIGSRTSIQDGSVLHITHAGPYNPDGFPLTIGDEVTVGHKVLLHGCTVGNRVLVGMGCIVMDGAVIEDEVILGAGSLVPPGKVLESGFLYVGSPAKKARPLTDKERAFFAYTAGNYVKLKDRHIAEGYAG
>FNEC01000023.1|SDJ78872.1|13430_15476_+|oligopeptidase-A-Metallo-peptidase.-MEROPS-family-M03A
MSANPLLQNYDLPPFSAIRPEHVKPAIEQILADNRAAIARILAEQGATPSWDGLVLAMDELHARLGAAWSPVSHLNAVCNSAELREAYEGCLPMLSAYWTELGQNRELFKAYEALAGSPAAASFDLAQKTILEHALRDFRLSGIDLPAEQQQRYAEIQARLSELGSRFSNQLLDATQAWTKHVTDEAALAGLTDSAKAQMQQAAQAKGLDGWLISLEFPSYFAVMTYAQDRALREEVYAAYCTRASDQGPNAGQNDNGPVMQEILDLRQELARLLGYANFSALSLATKMAESPEQVLHFLRDLAVRSKPYAQQDLDQLKAYAAEQGCAQLQSWDSGYYGEKLREARYSVSQEALRAYFPVDKVLSGLFAIVQKLYGIQIRELHDFERWHPDVRLFEIEEHGQHVGRFYFDLYARANKRGGAWMDGARDRRRDAAGQLIAPVAYLVCNFTPAVNGKPALLTHDEVTTLFHEFGHGLHHLLTRVEHAGASGINGVAWDAVELPSQFMENWCWEPEGLALISGHYETGAPLPQDILEKMLAAKNFQSGLMMVRQLEFSLFDFELHTSHGDGRNVLDVLEAVRDEVAVMRPPAYNRFANSFAHIFAGGYAAGYYSYKWAEVLSADAFSRFEEEGVFNPQTGAAFREAILAKGGSQEPMALFVAFRGREPSIDALLRHSGLTGEAA
>FNEC01000023.1|SDJ78913.1|15475_15742_+|hypothetical-protein
MAEVKKRFIAGAVCPACSEQDKIVMWDEDGVPHRECVACGYADTLNAQGQSVPKELATRVNVTGLKKPADPKVQGVQFFPNPKLKKKD
>FNEC01000023.1|SDJ78953.1|16027_18538_-|diguanylate-cyclase/phosphodiesterase-with-PAS/PAC-sensor(s)
MPYDQLPDVFAQILEQAIDGVVVLDENNRVLLFNAAAERLWGYSREAVLGQDVGLLLPDEVRPRLDASLDTEGIAGSRSEVPMRCRDGSRLWGSMSISHIEFDGKRLLTAFVKDCTLQRRQREQMDVLSLAANETDNAVIVTGREGRILYVNAGFSRMFGWNAEQALGRYPSELLQVPQASVRRWRQAGAGLFRSEELVRDLIGRPLWCSVVANPILDTRGQPVNSVMLLTDITHTKLHEVLQNKVLDALVRERPLVDVMDLVCREVERIAPEVKASILRVDAQGRMHPLAAPSLPEDFSQSIEGARMGPRAGSCGTAAYRGKAVMVSDIASDPLWDDYRHLVPPGLKACWSSPIKNSEGRVIGTFAFYYEQCRGPDELHLRLVDVSLPLVALALEREEARAHIRQLAFYDTLTGLPNRSLLLAEAEQAMTRIEDDEAEMAVLFIDLDRFKQINDSLGHPVGDELLRLVAARLQEVVREQGLVGRLSGDEFVVVLPYCGALLASQVAERILARLALAHRVGGVSLITLASIGISLFPSNGRDMETLLHRADIAMYQAKNGGRGSYRFFSDEMNQRAQERLALESALREAVQRQTLSLHYQPQVRLGDGGVHAVEALARWRHPQLGAVAPNRFIALAEECGIIGELSQWVLREACRQLADWRRRGIHIPAVAVNLSPADFRDPDLPARLQDLLRRNGLAGSDLVVEITEGMLLDNHPATLDILRAVHGLGVRLSMDDFGTGYSSLGYLHRLPIRELKLDRSFVADLREGTAAQALTDAVMNIGRSLELMVIAEGVEDEAQLELLRQQGYPVAQGYLFSRPLPAAALEEWLVRRGKGL
>FNEC01000023.1|SDJ78994.1|18815_20441_+|inorganic-phosphate-transporter,-PiT-family
MLDRYQLLQSLRATRISRMPVNPVLQEVASPTGQLLFFLLLGGGLVYTFGNLALDILAQGGQLRPNGTLLVLALALLIALGFEFINGFHDTANAVATVIYTNALPPQVAVGWSGLWNLLGVLFSSGAVAFGIVTLLPLDLLLRVDSDAGLAMIFALLGASILWNLGTWWLGLPVSSSHTLIGSIVGVSLAHGVLSGELGIDGSAWEQLQKVGYALLLSPLLGFIGAGLLLLGMRAVVRRKMLFSAPQGRRPPPLGIRALLVLTCTGVSFAHGSNDGQKGIGLIMLILAALMPLSFAVDRSQAPAQVQQLRELAHRAELQLRRLAPQDIPMAPRQVLLDYQNEQRLTPEVLPALAAQLHNIGARLRGHDDLTGLPDDEVLALHNELYLSVESIRQLDRTEQLFDVDTWSTLQALRDRSLDTVQFIPPWVKVAVALALGLGTLVGWRRIVTTVGEGIGKQPLTYAQGASAQLTAMLTIGAADIYGLPVSTTQVLSSGVAGTMAANGSGLQWQTLRNMLLAWVLTLPAAICLAALLYWSLRVLI
>FNEC01000023.1|SDJ79039.1|20885_21947_+|DNA-repair-photolyase
MSSILPPRGRGTASNPHNRFAPTRSEVEDDGWYQDEAPPCRATEVRSEQAKTVISRNQSPDVGFDRSVNPYRGCEHGCIYCFARPSHAYWDLSPGIDFETRLIAKTNLAERLEAELSKPGYVPRPIALGINTDAYQPLERDQRLTRQALEILLRFRHPLHIITKGSLILRDLDLLGELASLNLVSVAFSLTTLDNELKRIMEPRTASPGARLRAMRTLHEHGVPVSAVLAPMIPMVNDMELERLLEAARDNGARSAGYILLRLPLEIAELFQQWLQAHFPDRAEHVMSLIRQSRGGKDYDSRFGTRMHGEGAFADLLARRFQVAARRLGLDRRDYAGLDCSLFQVPRAQMSLF
>FNEC01000023.1|SDJ79077.1|22189_22903_+|carbonic-anhydrase
MNDKTHGEEHITENADEALRHIVEGFRQFREEVFPQQEALFKKLAHAQNPRAMFITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTAIEFAVMALGVHHIIVCGHSDCGAMKAVLDPQTLERMPTVKAWLRHAEVAKTVVEQNCGCASHETLGILTEENVVAQLDHLKTHPSVAARLASGQLFIHGWVYDIETSQIKAYDAEAGRFRPLDGEGPIPMATPRPRYRQ
>FNEC01000023.1|SDJ79123.1|23148_23787_-|hypothetical-protein
MNIAALRELIQQAHQLETRNGHLARLIHSQMASLHPSINLSGDDATQVLTRFVHAYIEQVPEFLEAATSVARNAGIEARIKPVLKVAEHFFLTPPDLLAGHDGLDALLDEAYLAHRLVEEVNDRYIAHFGQPLIPLDTTVANLVAHQLIGEPFANRLDEAVHHAVESMLDDSVFSSPAAQAYRARLSDPQTVTAWKQWPCLSRRFGVELHLN
>FNEC01000023.1|SDJ79161.1|24159_25284_+|cytochrome-c-oxidase-subunit-2
MLRHPRTWMGLLSLLVFAPAHAAWTVNMTPGATEVSRNVFDLHMTIFWICVVIGIIVFGAMFWSMIVHRRSTGQQPAHFHESTAVEILWTVVPFLILVVMAIPATRTLIHMYDTTEPELDVQITGYQWKWQYKYLGQDVEFFSNLATSQEQIHNRDPKDDHYLLEVDNPLVLPAGVKVRFLVTSSDVIHSWWVPAFAVKRDAIPGFVNEAWTKVDEPGIYRGQCAELCGKDHGFMPIVVDVKAKPEFDKWLAERKEEAAKLKELTSKEWTKEELVARGDKVYHTICAACHQPEGQGMPPMFPALKGSKIVTGPKEHHLETVFNGVPGTAMAAFGKQLSEVDIAAVITFERNAWGNNDGDMVTPQDVVAYKQKQK
>FNEC01000023.1|SDJ79214.1|25297_26893_+|cytochrome-c-oxidase-subunit-1
MSAVIDHPEHSHAGEHHHGPAKGLMRWVLTTNHKDIGTLYLWFSFCAFLLGGSFAMVIRAELFQPGLQIVEPAFFNQMTTMHGLVMVFGAVMPAFVGLANWMVPLMIGAPDMALPRMNNFSFWLLPAAFGLLVSTLFMPGGGPNFGWTFYAPLSTTFAPHSVTFFIFALHMMGMSSIMGAINVIATILNLRAPGMTLMKMPLFVWTWLITAFLLIAVMPVLAGCVTMMLMDIHFGTSFFSAAGGGDPVLFQHVFWFFGHPEVYIMILPAFGAVSAIIPAFSRKPLFGYTSMVYATASIAFLSFIVWAHHMFVVGIPLVGELFFMYATMLIAVPTGVKVFNWASTMWQGSLTFEAPMLFAVAFVILFTIGGFSGLMLAIAPADFQYQDTYFVVAHFHYVLVPGAIFGIFASVYYWIPKWTGHMYDETLAKLHFWLSFIGMNMAFFPMHFLGLAGMPRRIPDYNLQFANFNMVSSIGAFLFGTTQLLFLFIVIKTIRGGKPAPAKPWDGAEGLEWTVPSPAPYHTFSTPPEVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	FNEC01000053.1	38388-38419	2	0.938

1. spacer 1.5|12735|32|FNEC01000023|CRT matches to position: 38388-38419, mismatch: 2, identity: 0.938

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
caacgacgccgccgtgtgttcgttgtcgcaag	Protospacer
*********************.*.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	MN693903	Marine virus AFVG_250M471, complete genome	3878-3909	5	0.844
FNEC01000023_1	1.1\|12616\|29\|FNEC01000023\|PILER-CR	12616-12644	29	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1858068-1858096	6	0.793
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	78182-78213	6	0.812
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	NZ_CP023739	Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence	64045-64076	8	0.75
FNEC01000023_1	1.3\|12615\|32\|FNEC01000023\|CRT	12615-12646	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1858065-1858096	9	0.719
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	460868-460899	9	0.719
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	151904-151935	10	0.688
FNEC01000023_1	1.5\|12735\|32\|FNEC01000023\|CRT	12735-12766	32	NC_019202	Pseudomonas aeruginosa plasmid pKLC102, complete sequence	77613-77644	10	0.688

1. spacer 1.5|12735|32|FNEC01000023|CRT matches to MN693903 (Marine virus AFVG_250M471, complete genome) position: , mismatch: 5, identity: 0.844

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
cagtggcggcgccgggtgttcatcgtcgcaag	Protospacer
**..*.** ***** *****************

2. spacer 1.1|12616|29|FNEC01000023|PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 6, identity: 0.793

agatggagcgctatgcggcgcgcttgaac	CRISPR spacer
agatggggcgctatgcggcccgcgccatc	Protospacer
******.************ *** . * *

3. spacer 1.5|12735|32|FNEC01000023|CRT matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

caacg-acgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
-aacgcacgccgccatgtgttcatcgccggcgg	Protospacer
 **** ********.***********.**  .*

4. spacer 1.5|12735|32|FNEC01000023|CRT matches to NZ_CP023739 (Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence) position: , mismatch: 8, identity: 0.75

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
acaggacgccgccgtctattcatcgtcgcggc	Protospacer
  * *********** *.***********..

5. spacer 1.3|12615|32|FNEC01000023|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 9, identity: 0.719

agatggagcgctatgcggcgcgcttgaacaaa	CRISPR spacer
agatggggcgctatgcggcccgcgccatcctc	Protospacer
******.************ *** . * *

6. spacer 1.5|12735|32|FNEC01000023|CRT matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
gagccccgcctccgtgtgctcatcgtcgcgcc	Protospacer
 *.*  **** *******.**********.

7. spacer 1.5|12735|32|FNEC01000023|CRT matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 10, identity: 0.688

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
tgggaccggcgccgcgtgttcatcgtcgccaa	Protospacer
... . ** *****.************** *.

8. spacer 1.5|12735|32|FNEC01000023|CRT matches to NC_019202 (Pseudomonas aeruginosa plasmid pKLC102, complete sequence) position: , mismatch: 10, identity: 0.688

caacgacgccgccgtgtgttcatcgtcgcaag	CRISPR spacer
ttcccgtttcgccgcgtgttcatcgtcgccag	Protospacer
.  * .. .*****.************** **

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. FNEC01000005

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: FNEC01000005_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

FNEC01000005_1

49839-50300

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGTATGCGGGGATGAACCG	PILER-CR
GTGTTCCCCGCGTATGCGGGGATGAACCG	CRT

7 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

The CRISPR arrays of FNEC01000005_1

>merge|FNEC01000005|1|49839-50300|PILER-CR,CRT
GTGTTCCCCGCGTATGCGGGGATGAACCGACTCCTTGCGGGTGCGCTCTTGCTTGCGCTTAGTGTTCCCCGCGTATGCGGGGATGAACCGTTAGCGGCGGGACGATCTACTCTTCGAATAACGTGTTCCCCGCGTATGCGGGGATGAACCGGTTTTCTTCGGAGCTTCCATGTCGGTCGTGGCGTGTTCCCCGCGTATGCGGGGATGAACCGGCCTGGAACACCGGGGCGCCGAACTGGACGGAGTGTTCCCCGCGTATGCGGGGATGAACCGTTCTGCAGCTCGGCACGCCCCTGCTGGGCATCGTGTTCCCCGCGTATGCGGGGATGAACCGTCATAATCAGCTTCCTCCTAAGTGAGCAGGTTGTGTTCCCCGCGCGCTTGGGCGTGGGGGTGAACCGTACGTGAACAAGCGCTCCGAGATATGGGGTGAATGTTCCCCGCATATGCGGGGATGCCTCG

>FNEC01000005|1|1|49839-50111|PILER-CR
GTGTTCCCCGCGTATGCGGGGATGAACCG	ACTCCTTGCGGGTGCGCTCTTGCTTGCGCTTA
GTGTTCCCCGCGTATGCGGGGATGAACCG	TTAGCGGCGGGACGATCTACTCTTCGAATAAC
GTGTTCCCCGCGTATGCGGGGATGAACCG	GTTTTCTTCGGAGCTTCCATGTCGGTCGTGGC
GTGTTCCCCGCGTATGCGGGGATGAACCG	GCCTGGAACACCGGGGCGCCGAACTGGACGGA
GTGTTCCCCGCGTATGCGGGGATGAACCG

>FNEC01000005|1|1|49839-50300|CRT
GTGTTCCCCGCGTATGCGGGGATGAACCG	ACTCCTTGCGGGTGCGCTCTTGCTTGCGCTTA
GTGTTCCCCGCGTATGCGGGGATGAACCG	TTAGCGGCGGGACGATCTACTCTTCGAATAAC
GTGTTCCCCGCGTATGCGGGGATGAACCG	GTTTTCTTCGGAGCTTCCATGTCGGTCGTGGC
GTGTTCCCCGCGTATGCGGGGATGAACCG	GCCTGGAACACCGGGGCGCCGAACTGGACGGA
GTGTTCCCCGCGTATGCGGGGATGAACCG	TTCTGCAGCTCGGCACGCCCCTGCTGGGCATC
GTGTTCCCCGCGTATGCGGGGATGAACCG	TCATAATCAGCTTCCTCCTAAGTGAGCAGGTT
GTGTTCCCCGCGCGCTTGGGCGTGGGGGT	GAACCGTACGTGAACAAGCGCTCCGAGATATGGGGTGA
ATGTTCCCCGCATATGCGGGGATGCCTCG

Protein	Signature genes	Signature genes Name	Protein_function
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
FNEC01000005.1\|SDI43022.1\|38266_39283_-\|phosphate-starvation-inducible-protein-PhoH	unknown	unknown	gnl\|CDD\|224616
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	unknown	unknown	gnl\|CDD\|236222
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	unknown	unknown	gnl\|CDD\|224228
FNEC01000005.1\|SDI43173.1\|42012_43296_-\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
FNEC01000005.1\|SDI43289.1\|44978_47366_+\|Signal-transduction-histidine-kinase	unknown	unknown	gnl\|CDD\|274362
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|235387
FNEC01000005.1\|SDI43250.1\|44000_44798_-\|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|180561
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|237559
FNEC01000005.1\|SDI43094.1\|40737_41175_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370154
FNEC01000005.1\|SDI43057.1\|39371_40712_-\|tRNA-i(6)A37-thiotransferase-enzyme-MiaB	unknown	unknown	gnl\|CDD\|237673
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
FNEC01000005.1\|SDI43210.1\|43357_43981_-\|thiamine-phosphate-diphosphorylase	unknown	unknown	gnl\|CDD\|234590
FNEC01000005.1\|SDI43136.1\|41251_41797_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276807
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|183199

Protein	Function_ID	Function_description	E-value
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.07162e-62
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	3.17586e-105
FNEC01000005.1\|SDI43022.1\|38266_39283_-\|phosphate-starvation-inducible-protein-PhoH	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	1.98114e-156
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	gnl\|CDD\|236222	PRK08292, PRK08292, AMP nucleosidase; Provisional.	0
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.02794e-147
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.10046e-12
FNEC01000005.1\|SDI43173.1\|42012_43296_-\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	2.83359e-53
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.86508e-153
FNEC01000005.1\|SDI43289.1\|44978_47366_+\|Signal-transduction-histidine-kinase	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.09835e-72
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	3.59692e-95
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|235387	PRK05283, PRK05283, deoxyribose-phosphate aldolase; Provisional.	3.83916e-103
FNEC01000005.1\|SDI43250.1\|44000_44798_-\|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase	gnl\|CDD\|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	1.54752e-116
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	gnl\|CDD\|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	2.67928e-51
FNEC01000005.1\|SDI43094.1\|40737_41175_+\|hypothetical-protein	gnl\|CDD\|370154	pfam08850, DUF1820, Domain of unknown function (DUF1820). This family includes small functionally uncharacterized proteins around 100 amino acids in length.	2.94888e-61
FNEC01000005.1\|SDI43057.1\|39371_40712_-\|tRNA-i(6)A37-thiotransferase-enzyme-MiaB	gnl\|CDD\|237673	PRK14325, PRK14325, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	2.48592e-62
FNEC01000005.1\|SDI43210.1\|43357_43981_-\|thiamine-phosphate-diphosphorylase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	3.83032e-78
FNEC01000005.1\|SDI43136.1\|41251_41797_-\|hypothetical-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.48242e-19
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	gnl\|CDD\|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	4.49385e-164

>FNEC01000005.1|SDI43364.1|48125_49775_+|putative-acyl-CoA-dehydrogenase
MNLHQYAETHEVSNQVPPLDGANLYRVDLPLQEWLRRYDGGWAEARLDAYGALAGGPLMAAGFLANENKPVFKSHDRYGHRIDLVEFHPAYHELMRTAIEHGIPSMPWTDPRAGAHVARAGLSYLHSQAEAGTGCPLTMTFASVPAIRLQPDIAEKWLPKILATEYDPRNLPIEQKAGATIGMAMTEKQGGTDVRANTTRAYPVGIPGPGQAYELVGHKWFCSAPMCDAFLTLAYTDKGLTCFLLPRHRPDGTRNEFYVQRLKNKLGNWSNASSEVEYRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSALMRQALTQAAHHCAYRQVGGRVLAEQPLMQNVLADLALESEAALALTMRMGRALDHLHDEQEDKFARLVTAVGKYWICKRAPAMINEAAECLGGAGYVEDTILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDALFAELGDGHGDARLAAFIGNLKASFADTADIQFRARQLTEDVAVALQAKLLLEAGNATVADAFIGSRLGNGGRVYGTLPRGTDVEALVARATPHLA
>FNEC01000005.1|SDI43326.1|47481_48129_+|transcriptional-regulator,-TetR-family
MVYRLTEARLQKDVELRERILQLALARVAEGGFAALTMQGLAEEAGIATGSLYRHFRGKGELAAEVFARASQREVDALAVVLRGTGGPAGRLARGLRQFARRAWDSRRLAFALIAEPVDPEVDEQRLLYREAYAELFGELLEEGVRSGHFHCGPTSLIAACLVGAIAESLVGPLSPPARAARDAGQPSPGLEQVSQALVDFCLRAVGAPQPEEPR
>FNEC01000005.1|SDI43289.1|44978_47366_+|Signal-transduction-histidine-kinase
MQRWLILFLLLLSPLVGAVSFDEHTSRLPLGHAIDVFEDVRGTADIADITSAALADSFRRHDRDVLNAGYSRSVFWIRLDLDYRPQESQDPAHWLLELAYPPLDRLDLYLPGADGRYQLAQRTGDTLPFASRPISLTNYLFDLKLAPGKPLRVYLRLESQGSIQAPLTLWSPKAYMENLPGNVYVLGIIYGVLLVMLVYNLFIFVSVRDTSYLYYILYIASFGLYQVSVNGAGIEYFWPNSPWWANAATPFLIGSASLFGCQFARSFLHTREHSPWVDRTLLALMAVGALVMLLAFSASYALSLRLATYLALAFVVVIFSAGILAWLRGMRVARYFIFAWTAFLLGGTINTLMVLGFLPNVFFTMYASQIGSALEVGLLSLALADRINAMKEERTRILQESSRKLEQLNLELANSNRLKDEFLATVTHELRTPMSGVIGSLELMQTVPMDVELAQYQKTATGSARDMMRMVNDILALIELQAGKLYPRREPFSLRGLFDSLRAQYAPRAEAKGLRFDLQLDESLPDTLEGDAGKLAQTLGYLLDNAIKFTHQGGVGLRVDGQRQSDGVALRVAVQDSGIGFETPANDALYQRFHQLDGSLTREYGGLGIGLALCRQLTGLLGGQLQHHSTPGRGSRFVLELNLGQPAQGFSVPPRRAGGQALRRPDQCTVLVVEDNAINQLVIRGMLLKLGYRVRTADNGSEAIDLLRREGVDAVLLDCQMPIMDGFATCRAIRALPQGGELPVLAITAHSHSGDRERCLAAGMSDYLAKPVKFEELQTLLHDWLLCQPALPSHA
>FNEC01000005.1|SDI43250.1|44000_44798_-|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase
MKTPTSRPVVLCLSGHDPSGGAGLQADIEALIAQGCHAAPAVTALTVQDTVNVSDFRVLDREWVLAQANAVIADLPVAAVKLGMLGSVEMVDTVVEIMQSLPGVPLVCDPVLRAGGGGALGKDEVGYAIRERLFPVAAIATPNLPEARILAELPEGSADECAEKLLPYIRNLLITGGHGDESEVHNRLYGRDGSQHTFTCQRLPGSYHGSGCTLASALSGRLALGEELASAVRSALDYTWRTLRDAEAPGRGQYVPRRLPLDFCS
>FNEC01000005.1|SDI43210.1|43357_43981_-|thiamine-phosphate-diphosphorylase
MKLRGLYAITDSKLLADGRLLPYVEAALRGGARLLQYRDKSSDESRRLREAEALRELCERHGATLIVNDDAELAARLGVSVHLGQTDGSLAAARALLGRQAIIGATCHGSLQLADQAVAEGADYVAFGRFFQSLTKPGASEASPELLEQARARFANVPLVAIGGVTLENAPGLIGRGADLLAVINALFAADTPAEVERRARAFAALF
>FNEC01000005.1|SDI43173.1|42012_43296_-|glutamate-1-semialdehyde-2,1-aminomutase
MSRSELLFANAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVVDEDDKRYVDYVGSWGPMILGHAHPEVLDAVRRQLEHGLSYGAPTALEVEMADLVCSLVPSMDMVRMVSSGTEATMSAIRLARGYTGRDDIIKFEGCYHGHSDSLLVKAGSGALTFGVPNSPGVPADFAKHTLTLPFNDLEAVEKALDEYGQKVACIIVEPVAGNMNCVPPAPGFLQGLRKACDKHGVVLIFDEVMTGFRVALGSAQALYGVTPDLSTFGKIIGGGMPVGAFGGKREIMQRISPLGPVYQAGTLSGNPLAMAAGLTTLKLISRPGFHDELTDYTSRMLQGLQERADAAGIPFVTTQAGGMFGLYFSGADDIVTFADVMASDAERFKRFFHLMLEGGVYLAPSAYEAGFTSIAHGDTELKLTLDAAERAFAALK
>FNEC01000005.1|SDI43136.1|41251_41797_-|hypothetical-protein
MYRSGRALLLGSLLFISPLFAQAGGNSLLVPATGRCTLNTVPEQLQQALASCQQIANGGDAEAQFELGEYYYTGERAPRDFPAALRWYEKASLQGHAQAQWRLGTMFFRGEGVKANNIQAYIVLKMAAVNGAEDAMDSADLVAEQMSKDELDIASKVLGQIFRNYLIELQTAGNTPFSPLP
>FNEC01000005.1|SDI43094.1|40737_41175_+|hypothetical-protein
MTGHYSGARGPFLGLRARRLCYDSRLFSQSCHPPFMNKRENPIYKVVFLNQGQVFEMYAKQIYQSELWGFLEIEEFVFGERTQVVVDPSEEKLKAQFEGVIRSFVPLHAIIRIDEVERLGTPKISEAKGGGNVMPFPMPMPDKNS
>FNEC01000005.1|SDI43057.1|39371_40712_-|tRNA-i(6)A37-thiotransferase-enzyme-MiaB
MAKKLFIQTHGCQMNEYDSSRMADLLGEEHALELTEKAEDADVILLNTCSIREKAQEKVFSELGAWRALKQQKPELVIGVGGCVASQEGAAIRERAPFVDVVFGPQTLHRLPEMIDAARTTRRPQVDVSFPEIEKFDRLPEPRVDGPTAFVSVMEGCSKYCSFCVVPYTRGEEVSRPFDDVLAEVIHLAENGVKEVTLLGQNVNGFRGATHDGRIADFAELLRVVAEVDGIERIRYTTSHPLEFSDALIAAHAELPQLVPFVHLPVQSGSDRVLAAMKRNHTALEYKSRIRKLKAAVPDICISSDFIVGFPGETDKDFEQTMKLVEEVGFDYSFVFIYSQRPGTPASDLADDTPDEVKKQRLMILNTRLQQQGFEISRRMVGSVQRILVTDYSKRDPGQLQGRTANNRVVNFACDNPRLIGQFAEVEIYEALPNSLRGRLVEPTRH
>FNEC01000005.1|SDI43022.1|38266_39283_-|phosphate-starvation-inducible-protein-PhoH
MNAPLDLHRFTLEPFDARSFANLCGQFDEHLHQIEKRLDIEIRNRGNQFELVGEAARTQAAEHLLQRLYREAQSGTELTPDMVHLFLQESGLEDLASASEVPSITLKTRKAHIRPRGANQQRYVKAILDHDINFGIGPAGTGKTYLAVACAVDALEREQIRRILLVRPAVEAGEKLGFLPGDLSQKIDPYLRPLYDALYEMLGFETVAKLIERQVIEVAPLAYMRGRTLNNSFIILDESQNTTIEQMKMFLTRIGFGSTAVITGDITQVDLPRGTRSGLKHVMEVLRDVPGISFTHFKPKDVVRHPLVQRIVEAYERFEARQPVRLDGERAPRETGDA
>FNEC01000005.1|SDI43396.1|50423_53108_+|CRISPR-associated-helicase,-Cas3-family
MGEGRLSFSGLSAAGRAVWAKSGDEGGHGLLAHLLDVAAVAETLLEIEPASTRRWASRALGVDEAEVGRWVAAIAGLHDFGKAIPGFQAKWPDGMAADQAHGLAFPASACNQGRHDLATASLLGRALLGVVAIEAGWLRDAVQAVSAHHGYHFLPDETNQGRPLAEPATWPAVRDEILRGYWQVLAPNGAPALDELSLPAVNWLAGLTSAADWIASNPEWFVPDQRGFDDLADYFRNACRLARLAFSQIGWRPYRPLLAGPADTDAVLARIVGRPGLSARPLQRVGDQLLQGVRGPALVVVEAPMGEGKTEFAFLAHLRLQAANGHRGLYVALPTQATGNALFDRALTFLEQFTTGPLDVQLVHGGAGMNEQVRHLRGIDHSSAESLSASAWFSQRKRPLLSAYGVGTIDQALFAALNVKHHFVRLWGLANRVVVLDEVHAYDTYTSGLIAALLRWLKALGCSVVLMSATLPLGRRAELLRAWGVSPDQVPELDYPRLLVADEGGIQGEHFGARPQSSIRLAGLDESLDTLADTAVELLAGGGCGALIVNTVERAQKLYIGLRQRLGDEVPLLLFHARFPADERAEREREVLAAFGTQGDRPRRALLVATQVAEQSLDIDFDFMLSDLAPVDLLLQRAGRLHRHDRERPAKHVQACLWVAGLRNGELPELENTAWRHVYDAYILLRTWALLRDGESLSLPADIDRLVQAVYGDDPLPDGLEEKARALIEIESYGEYLARVQKERRESFNIAIDPAEEPRSAYNGKPRGSEEGEGVGLENRTRLGPESITLIPVEEVEGGWCVRPGEPSFDPARPLDDAQARRLYERQLKVSRRALVAHFKRIDLPAAFEHPLLRNCYPLPLRQGQYPGEGLSLRLDSVLGLVYGPVDGANEGMA
>FNEC01000005.1|SDI43426.1|53104_54670_+|CRISPR-associated-protein,-Cse1-family
MNKDFCLLDEPWLLVRFADGRVEELGLLEVFARSGEIVALADTAPPNLVAHYRLLLAITHRALSEAFGRWREKDRARWFREGLPQAEIRGYLETWRERFWLFHPEQPFMQVAALATAEETRDKYKPWTQIALASASGNAPMVFDHACDLTPTAIRPALALATLLGFLQFTPGGLVKSLRDSDKAGALANTAAVLPLGENLAQTLCLALHPAPRNDAEPDLPTWERESPSIAALRGEPLLATGPNDRYTRLSRAVLLRREADGNVRWLHYAAGLALGEDPNAPDPMASFRAGSNGLVRLTFSEGRALWRDLPALVPHAGAGSQAAAVVQNAIGLHGNLAHFEPVHQPLLVAGLASDQAKLLRWRLERISLPSALLLEPDKALYLRGRLELAETLFLELRRLASGMLAETLPDPASKDTRARARSLVDAGPLAASYFAAAERALPELLDGIGAGALDEAESLWRGVLHRSAEAAWQQVLAGLGYSSRALRADARYWPRFRGLLKAQLAISDDPTIDVDKEAMS
>FNEC01000005.1|SDI43460.1|54666_55188_+|CRISPR-associated-protein,-Cse2-family
MSDHAEKFIEYLAALKDWDRGAMAALRHSLAFEPGAYPRAFPYVERFAGAAAHERDAHRLALYAVAGLFARHPLRRPQSFAAALGELLRLRQSPSIESRFVALLGADAENIVEYLRQAVSLLAADGIGFDHARLLVDLSQWLNPGTDPSRLRQRWARDFYRAAQPVSEYTDSE
>FNEC01000005.1|SDI43496.1|55199_56333_+|CRISPR-associated-protein,-Cse4-family
MSLFLEFHLIQNFAPSNLNRDDTGAPKDAIFGGQRRARVSSQCFKRAVRLAAKQHELLPEANRGIRTKKLKALLLERLAGRDAEEAGAKVEAALGAAGLKLKDDGKTEYLLFLGEGEVAAFAALIEQHWDELPVGGDKKSKKDAKASLPAEIIKKAKALLDGGKAVDVALFGRMLADMPAVNQDAACQVAHAISTHRVEREFDYFTAVDDKGDEGETGAGMIGQVEFNSATLYRYAVLDLRKLLGNLQEDRELALSAVEAFTRALALAIPTGKQNSFAAHNPPEFIGVCLRHASPLSLANAFERPVSPRADQALTEQSVERLTAYEDKLAPVYGAPQDRWLSLDLTDRWPADKGERLASLAALAQRARELAADALGA
>FNEC01000005.1|SDI43529.1|56335_57007_+|CRISPR-associated-protein,-Cas5e-family
MATLLLRLQGPMQSWGTTSRFDERDTQLEPSKSGVLGLVCAALGRDRREPVDDLAALRMGVRVEREGVPMRDYQTATGVVIASSGKPDLDRTVVSPRYYLADAVFLVGLEGERALLADVHAALARPVWPLALGRKSFVPTSPVHLPEGLRDQSLEYALANCFCLLEGGTPRTPRRLLLEHPNEGSVRLDQPVAPFAERRFGPRFVKSALFTPGGAHAPDPTAA
>FNEC01000005.1|SDI43565.1|56981_57593_+|CRISPR-associated-protein,-Cse3-family
MHLTRLRLDPRSAQARRDLGDAYEMHRTLVRAFVRDEQHSPPRILWRAEPTSAWSDPVVLVQAQEVADWSVLQALPNYLKGPVETRPLAPEQWLQEGERFRFRLFANPTVTREGKRLGLVAEDAQLAWLARQGERLGFSVEAALVTGSELLRSRKSEHRISLLRVCFEGRLQVRDPAALAQALRAGIGPGKAFGCGLLSLGRG
>FNEC01000005.1|SDI43603.1|57637_58510_+|CRISPR-associated-protein,-Cas1-family
MIFIQYGQIDVLDGAFVVIDKSGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGESGVRLYASGQPGGARADRLLYQARLALDDELRLKVVRKMYELRFQEPAPARRSVEQLRGIEGARVRGTYKLLARQYGVDWRSRNYDHQQWDAADIPNRCLSAATACLYGITEAAVLAAGYAPAIGFIHTGKPLSFVYDVADLFKFETVVPLAFRIAAQSPPEPERAVRLACRDLFRSSKLLGRIIPSIEEVLAAGGISPPEAPPESVPPAIPNPEGIGEAGHRSQG
>FNEC01000005.1|SDI43631.1|58506_58806_+|CRISPR-associated-protein,-Cas2-family
MSFLVVVTENVPPRLRGRLAIWLLEVRAGVYIGDVSRRTREMIWQQLSEGHGDGNVVMAWASAHESGYEFQTLGPNRRLPVEFDGLRLVAFQPLDSPDL
>FNEC01000005.1|SDI43665.1|59813_61289_+|AMP-nucleosidase
MNAELGDAFVVAHTAEEAVDRLAALHQRATGALSQALRRYLKTREQPAAEERALFRYPLLRLSYLCQGEVPSTTRAYAKVQTPGNYAVTITHPEAFRKYLLEQLRPLMEDFTVRVEVGPSEQNIPYPYVVEQGDELAGSGVTAAELARVFPSTDLSATSDGIADGLYQWEGADPMPLALFDAARTDFSLRRLVHYTGSDWRCVQPWILLTNYHRYVDQFIHMGLERLHEDPRFVRMVLPGNVVIERDMDRGEANAIIAGVEWHRFQMPAYHLIASDGDGVTLINIGVGPSNAKNITDHLAVLRPHCWLMIGHCGGLRQSQTIGDYVLAHAYMRRDGILDRVLPPHIPIPALAEVQVALQEAAALVTGERGEALKRRLRTGTVLTYDDRNWELHWAQERPLINLARAVAVDMESGTIAAQGYRLRVPYGTLLCVSDKPLHSEIKLPGAASAFYQRAVSQHLAIGIAAVDLLRTQLNSLHSRKLRSFDEPPFR
>FNEC01000005.1|SDI43693.1|61373_62132_+|deoxyribose-phosphate-aldolase
MAEPLQPTRAERAARLLSLLDLTSLNADDDMPRIVQLCRRALTPYGEVAAVCVYPRFVHVARRTLNGFGARAVKVASVCNFPAGDAPLAEVVEEVRRTLAEGADEIDLVYPWQALKAGRADGAVELIRACKALCGPYHRLKVIIESGELAEPELIRTACREAIAGGADFLKSSTGKVAVNATPEAARVMLECIVETGGKVGFKVAGGIRSLDDAEVYLAIAQEMLGDDWITSEHLRFGASALLDELLREMEA

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Crispr_ID: FNEC01000005_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

FNEC01000005_2

58876-59267

TypeI-E

I-E

Consensus_repeat	Method
TTCCCCGCAGGTGCGGGGATGAACCG	CRT
GTGTTCCCCGCAGGTGCGGGGATGAACCGGA	PILER-CR

6 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of FNEC01000005_2

>merge|FNEC01000005|2|58876-59267|CRT,PILER-CR
TTCCCCGCAGGTGCGGGGATGAACCGTTCCCGCCAGGAGCCCCCTGATGTCCACTATCGTGTTCCCCGCAGGTGCGGGGATGAACCGACGGCATTCACAACCGTAGCGTCAGGCAACTTGTGTTCCCCGCAGGTGCGGGGATGAACCGGTCAGGACGCTGATGACGGTCCAGCGCACCCGGTATTCCCCGCAGGTGCGGGGATGAACCGGTCAGGACGCTGATGACGGTCCAGCCGATGATGTGTTCCCCGCAGGTGCGGGGATGAACCGGAAACCCCATGAGCGATTTCAAGAAAGGCCGGGTGTTCCCCGCAGGTGCGGGGATGAACCGGACCCGCACTATGCGGCTGTCCTGGGCACCCGGTATTCCCCGCAGGTGCGGGGATGAACCG

>FNEC01000005|2|2|58876-59267|CRT
TTCCCCGCAGGTGCGGGGATGAACCG	TTCCCGCCAGGAGCCCCCTGATGTCCACTATCGTG
TTCCCCGCAGGTGCGGGGATGAACCG	ACGGCATTCACAACCGTAGCGTCAGGCAACTTGTG
TTCCCCGCAGGTGCGGGGATGAACCG	GTCAGGACGCTGATGACGGTCCAGCGCACCCGGTA
TTCCCCGCAGGTGCGGGGATGAACCG	GTCAGGACGCTGATGACGGTCCAGCCGATGATGTG
TTCCCCGCAGGTGCGGGGATGAACCG	GAAACCCCATGAGCGATTTCAAGAAAGGCCGGGTG
TTCCCCGCAGGTGCGGGGATGAACCG	GACCCGCACTATGCGGCTGTCCTGGGCACCCGGTA
TTCCCCGCAGGTGCGGGGATGAACCG

>FNEC01000005|2|2|59056-59208|PILER-CR
GTATTCCCCGCAGGTGCGGGGATGAACCGGT	CAGGACGCTGATGACGGTCCAGCCGATGAT
GTGTTCCCCGCAGGTGCGGGGATGAACCGGA	AACCCCATGAGCGATTTCAAGAAAGGCCGG
GTGTTCCCCGCAGGTGCGGGGATGAACCGGA

Protein	Signature genes	Signature genes Name	Protein_function
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
FNEC01000005.1\|SDI43836.1\|64824_65304_-\|transcriptional-regulator,-AsnC-family	unknown	unknown	gnl\|CDD\|224439
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
FNEC01000005.1\|SDI43882.1\|65747_66896_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369035
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	unknown	unknown	gnl\|CDD\|236222
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	unknown	unknown	gnl\|CDD\|224228
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842
FNEC01000005.1\|SDI43988.1\|68297_68714_-\|hypothetical-protein	unknown	unknown	unknown
FNEC01000005.1\|SDI43765.1\|63583_64192_+\|ribosomal-large-subunit-pseudouridine-synthase-E	unknown	unknown	gnl\|CDD\|211334
FNEC01000005.1\|SDI43804.1\|64199_64403_-\|Protein-of-unknown-function	unknown	unknown	gnl\|CDD\|378526
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|235387
FNEC01000005.1\|SDI43734.1\|62441_63488_-\|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily	unknown	unknown	gnl\|CDD\|293841
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|237559
FNEC01000005.1\|SDI43917.1\|66888_67779_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|181919
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
FNEC01000005.1\|SDI43950.1\|67780_68296_-\|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)	unknown	unknown	gnl\|CDD\|225200
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|183199

Protein	Function_ID	Function_description	E-value
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.07162e-62
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	3.17586e-105
FNEC01000005.1\|SDI43836.1\|64824_65304_-\|transcriptional-regulator,-AsnC-family	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	9.68709e-50
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.86508e-153
FNEC01000005.1\|SDI43882.1\|65747_66896_+\|hypothetical-protein	gnl\|CDD\|369035	pfam06682, SARAF, SOCE-associated regulatory factor of calcium homoeostasis. SARAF is as family of eukaryotic proteins embedded in the ER. SARAF is SOCE-associated regulatory factor, where SOCE is store operated calcium entry. ie a mechanism governing calcium homoeostasis in the cell and the mitochondria. SOCE involves the enabling of Ca2+ release-activated Ca2+ (CRAC) channels. SARAF is a single pass ER membrane protein whose systolic-facing domain is responsible for activity and whose luminary-facing domain carries out a regulatory function in conjunction with another membrane protein STIM, an ER single pass membrane protein that detects changes in ER Ca2+ levels through its EF-hand, conserved Ca2+ binding domain. STIM is the major target for SARAF regulation, and thus SARAF negatively regulates the SOCE entry of calcium into cells protecting them from overfilling.	1.87483e-05
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	gnl\|CDD\|236222	PRK08292, PRK08292, AMP nucleosidase; Provisional.	0
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	2.48592e-62
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.10046e-12
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	2.83359e-53
FNEC01000005.1\|SDI43765.1\|63583_64192_+\|ribosomal-large-subunit-pseudouridine-synthase-E	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	6.80296e-90
FNEC01000005.1\|SDI43804.1\|64199_64403_-\|Protein-of-unknown-function	gnl\|CDD\|378526	pfam10981, DUF2788, Protein of unknown function (DUF2788). This bacterial family of proteins have no known function.	1.51872e-11
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|235387	PRK05283, PRK05283, deoxyribose-phosphate aldolase; Provisional.	3.83916e-103
FNEC01000005.1\|SDI43734.1\|62441_63488_-\|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily	gnl\|CDD\|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	7.11378e-82
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	gnl\|CDD\|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	2.67928e-51
FNEC01000005.1\|SDI43917.1\|66888_67779_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|181919	PRK09509, fieF, CDF family cation-efflux pump FieF.	2.6584e-112
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	3.59692e-95
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.02794e-147
FNEC01000005.1\|SDI43950.1\|67780_68296_-\|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	1.79022e-35
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	gnl\|CDD\|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	4.49385e-164

>FNEC01000005.1|SDI43631.1|58506_58806_+|CRISPR-associated-protein,-Cas2-family
MSFLVVVTENVPPRLRGRLAIWLLEVRAGVYIGDVSRRTREMIWQQLSEGHGDGNVVMAWASAHESGYEFQTLGPNRRLPVEFDGLRLVAFQPLDSPDL
>FNEC01000005.1|SDI43603.1|57637_58510_+|CRISPR-associated-protein,-Cas1-family
MIFIQYGQIDVLDGAFVVIDKSGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGESGVRLYASGQPGGARADRLLYQARLALDDELRLKVVRKMYELRFQEPAPARRSVEQLRGIEGARVRGTYKLLARQYGVDWRSRNYDHQQWDAADIPNRCLSAATACLYGITEAAVLAAGYAPAIGFIHTGKPLSFVYDVADLFKFETVVPLAFRIAAQSPPEPERAVRLACRDLFRSSKLLGRIIPSIEEVLAAGGISPPEAPPESVPPAIPNPEGIGEAGHRSQG
>FNEC01000005.1|SDI43565.1|56981_57593_+|CRISPR-associated-protein,-Cse3-family
MHLTRLRLDPRSAQARRDLGDAYEMHRTLVRAFVRDEQHSPPRILWRAEPTSAWSDPVVLVQAQEVADWSVLQALPNYLKGPVETRPLAPEQWLQEGERFRFRLFANPTVTREGKRLGLVAEDAQLAWLARQGERLGFSVEAALVTGSELLRSRKSEHRISLLRVCFEGRLQVRDPAALAQALRAGIGPGKAFGCGLLSLGRG
>FNEC01000005.1|SDI43529.1|56335_57007_+|CRISPR-associated-protein,-Cas5e-family
MATLLLRLQGPMQSWGTTSRFDERDTQLEPSKSGVLGLVCAALGRDRREPVDDLAALRMGVRVEREGVPMRDYQTATGVVIASSGKPDLDRTVVSPRYYLADAVFLVGLEGERALLADVHAALARPVWPLALGRKSFVPTSPVHLPEGLRDQSLEYALANCFCLLEGGTPRTPRRLLLEHPNEGSVRLDQPVAPFAERRFGPRFVKSALFTPGGAHAPDPTAA
>FNEC01000005.1|SDI43496.1|55199_56333_+|CRISPR-associated-protein,-Cse4-family
MSLFLEFHLIQNFAPSNLNRDDTGAPKDAIFGGQRRARVSSQCFKRAVRLAAKQHELLPEANRGIRTKKLKALLLERLAGRDAEEAGAKVEAALGAAGLKLKDDGKTEYLLFLGEGEVAAFAALIEQHWDELPVGGDKKSKKDAKASLPAEIIKKAKALLDGGKAVDVALFGRMLADMPAVNQDAACQVAHAISTHRVEREFDYFTAVDDKGDEGETGAGMIGQVEFNSATLYRYAVLDLRKLLGNLQEDRELALSAVEAFTRALALAIPTGKQNSFAAHNPPEFIGVCLRHASPLSLANAFERPVSPRADQALTEQSVERLTAYEDKLAPVYGAPQDRWLSLDLTDRWPADKGERLASLAALAQRARELAADALGA
>FNEC01000005.1|SDI43460.1|54666_55188_+|CRISPR-associated-protein,-Cse2-family
MSDHAEKFIEYLAALKDWDRGAMAALRHSLAFEPGAYPRAFPYVERFAGAAAHERDAHRLALYAVAGLFARHPLRRPQSFAAALGELLRLRQSPSIESRFVALLGADAENIVEYLRQAVSLLAADGIGFDHARLLVDLSQWLNPGTDPSRLRQRWARDFYRAAQPVSEYTDSE
>FNEC01000005.1|SDI43426.1|53104_54670_+|CRISPR-associated-protein,-Cse1-family
MNKDFCLLDEPWLLVRFADGRVEELGLLEVFARSGEIVALADTAPPNLVAHYRLLLAITHRALSEAFGRWREKDRARWFREGLPQAEIRGYLETWRERFWLFHPEQPFMQVAALATAEETRDKYKPWTQIALASASGNAPMVFDHACDLTPTAIRPALALATLLGFLQFTPGGLVKSLRDSDKAGALANTAAVLPLGENLAQTLCLALHPAPRNDAEPDLPTWERESPSIAALRGEPLLATGPNDRYTRLSRAVLLRREADGNVRWLHYAAGLALGEDPNAPDPMASFRAGSNGLVRLTFSEGRALWRDLPALVPHAGAGSQAAAVVQNAIGLHGNLAHFEPVHQPLLVAGLASDQAKLLRWRLERISLPSALLLEPDKALYLRGRLELAETLFLELRRLASGMLAETLPDPASKDTRARARSLVDAGPLAASYFAAAERALPELLDGIGAGALDEAESLWRGVLHRSAEAAWQQVLAGLGYSSRALRADARYWPRFRGLLKAQLAISDDPTIDVDKEAMS
>FNEC01000005.1|SDI43396.1|50423_53108_+|CRISPR-associated-helicase,-Cas3-family
MGEGRLSFSGLSAAGRAVWAKSGDEGGHGLLAHLLDVAAVAETLLEIEPASTRRWASRALGVDEAEVGRWVAAIAGLHDFGKAIPGFQAKWPDGMAADQAHGLAFPASACNQGRHDLATASLLGRALLGVVAIEAGWLRDAVQAVSAHHGYHFLPDETNQGRPLAEPATWPAVRDEILRGYWQVLAPNGAPALDELSLPAVNWLAGLTSAADWIASNPEWFVPDQRGFDDLADYFRNACRLARLAFSQIGWRPYRPLLAGPADTDAVLARIVGRPGLSARPLQRVGDQLLQGVRGPALVVVEAPMGEGKTEFAFLAHLRLQAANGHRGLYVALPTQATGNALFDRALTFLEQFTTGPLDVQLVHGGAGMNEQVRHLRGIDHSSAESLSASAWFSQRKRPLLSAYGVGTIDQALFAALNVKHHFVRLWGLANRVVVLDEVHAYDTYTSGLIAALLRWLKALGCSVVLMSATLPLGRRAELLRAWGVSPDQVPELDYPRLLVADEGGIQGEHFGARPQSSIRLAGLDESLDTLADTAVELLAGGGCGALIVNTVERAQKLYIGLRQRLGDEVPLLLFHARFPADERAEREREVLAAFGTQGDRPRRALLVATQVAEQSLDIDFDFMLSDLAPVDLLLQRAGRLHRHDRERPAKHVQACLWVAGLRNGELPELENTAWRHVYDAYILLRTWALLRDGESLSLPADIDRLVQAVYGDDPLPDGLEEKARALIEIESYGEYLARVQKERRESFNIAIDPAEEPRSAYNGKPRGSEEGEGVGLENRTRLGPESITLIPVEEVEGGWCVRPGEPSFDPARPLDDAQARRLYERQLKVSRRALVAHFKRIDLPAAFEHPLLRNCYPLPLRQGQYPGEGLSLRLDSVLGLVYGPVDGANEGMA
>FNEC01000005.1|SDI43364.1|48125_49775_+|putative-acyl-CoA-dehydrogenase
MNLHQYAETHEVSNQVPPLDGANLYRVDLPLQEWLRRYDGGWAEARLDAYGALAGGPLMAAGFLANENKPVFKSHDRYGHRIDLVEFHPAYHELMRTAIEHGIPSMPWTDPRAGAHVARAGLSYLHSQAEAGTGCPLTMTFASVPAIRLQPDIAEKWLPKILATEYDPRNLPIEQKAGATIGMAMTEKQGGTDVRANTTRAYPVGIPGPGQAYELVGHKWFCSAPMCDAFLTLAYTDKGLTCFLLPRHRPDGTRNEFYVQRLKNKLGNWSNASSEVEYRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSALMRQALTQAAHHCAYRQVGGRVLAEQPLMQNVLADLALESEAALALTMRMGRALDHLHDEQEDKFARLVTAVGKYWICKRAPAMINEAAECLGGAGYVEDTILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDALFAELGDGHGDARLAAFIGNLKASFADTADIQFRARQLTEDVAVALQAKLLLEAGNATVADAFIGSRLGNGGRVYGTLPRGTDVEALVARATPHLA
>FNEC01000005.1|SDI43326.1|47481_48129_+|transcriptional-regulator,-TetR-family
MVYRLTEARLQKDVELRERILQLALARVAEGGFAALTMQGLAEEAGIATGSLYRHFRGKGELAAEVFARASQREVDALAVVLRGTGGPAGRLARGLRQFARRAWDSRRLAFALIAEPVDPEVDEQRLLYREAYAELFGELLEEGVRSGHFHCGPTSLIAACLVGAIAESLVGPLSPPARAARDAGQPSPGLEQVSQALVDFCLRAVGAPQPEEPR
>FNEC01000005.1|SDI43665.1|59813_61289_+|AMP-nucleosidase
MNAELGDAFVVAHTAEEAVDRLAALHQRATGALSQALRRYLKTREQPAAEERALFRYPLLRLSYLCQGEVPSTTRAYAKVQTPGNYAVTITHPEAFRKYLLEQLRPLMEDFTVRVEVGPSEQNIPYPYVVEQGDELAGSGVTAAELARVFPSTDLSATSDGIADGLYQWEGADPMPLALFDAARTDFSLRRLVHYTGSDWRCVQPWILLTNYHRYVDQFIHMGLERLHEDPRFVRMVLPGNVVIERDMDRGEANAIIAGVEWHRFQMPAYHLIASDGDGVTLINIGVGPSNAKNITDHLAVLRPHCWLMIGHCGGLRQSQTIGDYVLAHAYMRRDGILDRVLPPHIPIPALAEVQVALQEAAALVTGERGEALKRRLRTGTVLTYDDRNWELHWAQERPLINLARAVAVDMESGTIAAQGYRLRVPYGTLLCVSDKPLHSEIKLPGAASAFYQRAVSQHLAIGIAAVDLLRTQLNSLHSRKLRSFDEPPFR
>FNEC01000005.1|SDI43693.1|61373_62132_+|deoxyribose-phosphate-aldolase
MAEPLQPTRAERAARLLSLLDLTSLNADDDMPRIVQLCRRALTPYGEVAAVCVYPRFVHVARRTLNGFGARAVKVASVCNFPAGDAPLAEVVEEVRRTLAEGADEIDLVYPWQALKAGRADGAVELIRACKALCGPYHRLKVIIESGELAEPELIRTACREAIAGGADFLKSSTGKVAVNATPEAARVMLECIVETGGKVGFKVAGGIRSLDDAEVYLAIAQEMLGDDWITSEHLRFGASALLDELLREMEA
>FNEC01000005.1|SDI43734.1|62441_63488_-|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily
MPKARRSPWLITLLNLAGRLGGGYRGPQNTNFDGLRFRNLDAKPHHGFREFLKWQLERDRQLAWIEQPGPERRPETPARVSGEELRVTYVNHATLLIQHRGLNILTDPLWCERTSPFSFVGPKRHHPPGLALDELPPINLILVSHNHYDHLDVGSLGELARRFPQAKVVTGLGNAELIRACGFVEVHELDWWQSLPLHEGMRLTGVPAQHWSARSRYDTNRTLWLGFVLESADGPVLFPGDTGLGPEFGLIRERFGPMRFAALPIGAYEPRWFMRHHHMNPDDAVQAHRTLESQCSMAIHFGTFRLSDEGQFAPVHDLARALDEQGVDSQAFRAPKPGEQWLVGRMGG
>FNEC01000005.1|SDI43765.1|63583_64192_+|ribosomal-large-subunit-pseudouridine-synthase-E
MPRPPRPAPRRPAPRRVAKAPPAQPRLILLNKPFDVLTQFSDGEGRATLKDYVPVPGVYPAGRLDHDSEGLLLLTNDGRLQARIADPRHKLPKTYWVQVEGEPDEEQLQRLREGVQLNDGPTLPAEARRIDEPRLWERVPPVRFRKSVPTAWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWGLDGLQPGEWREVQP
>FNEC01000005.1|SDI43804.1|64199_64403_-|Protein-of-unknown-function
MNESFEDWMMYGLVSALVLFMAFIVWDLAKKSKAGRMGTMVLFFALGLGVFGFLVKSFVVAGLEGGF
>FNEC01000005.1|SDI43836.1|64824_65304_-|transcriptional-regulator,-AsnC-family
MNKLDRYDLRILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYILRQVALLDSKKLGLSLTAFVLIGMDRHTPERFEHFQSIIAQCPEVLECSLVTGMDADYQLKVMVPDMEHYQHFLLGTLTRIEGVTSVRSSFVLRNIMASTELPLEHLRS
>FNEC01000005.1|SDI43882.1|65747_66896_+|hypothetical-protein
MKSGIWCLASVGLLSLAIAGQAFAEGQGPGHGGQGGHGGGNGGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGSQASQGQGRPQNNWNGQWQGRPSHDDRGPDHRPGNWTTQWSSPSQGGGNGRGSDRRPGDWTTQWPGLNHGDRDDHGPGRPSAGGGSWQGRPPSAPGNAWHGRPGGNWGPHPSNWRPGYVVDRVPSGYYRVPWRGSDYFFNDGYWYRPHGARYVVVTPPYGVRVSYLPSYAEQLWFGSMLYFLAAGTYYLFDNSSQTYEVVPPPPQVAQAPLPTGNPYDVIAYPMYGQSPQQQAQDHYECHTWAVGQSGFDPAMAGYAPSQQAVDAYRGALGSCMQGRGYSVN
>FNEC01000005.1|SDI43917.1|66888_67779_-|cation-diffusion-facilitator-family-transporter
MDKDRARLLRLATSASLAVAVILVVTKALAWWYSGSVSLLAGLTDSLLDGAASLLNLLAVRYALRPADEDHRYGHGKAESLSGMGQALFISVSAVLIGTQALDRLQHPEPLGATGWGILVMLLSLALTVALLALQRRVIKRTGSLAVQADSLHYRSDLLLNGSILVALLLAHYGFPRMDAVFGLGIAAYILWSAVRIARESVAVLMDEELPADVSERMLELVRQVPGVAGAHDLRTRISGDRWFVQLHLELPGDMRLSQAHALCDQAVLAIRAEFPRAEVLVHADPLEVVGRETIS
>FNEC01000005.1|SDI43950.1|67780_68296_-|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)
MHAVLGRHLEKLLDYHLWAHERILEAVAPLDEAAYREPRGLFFGSLHGTLNHLAVVDRIWLDRVAGRPWQFTRLDTEAAPDRAALADFLREGVQGWKQWLARQDERDLGKQLEYRNMAGQEHRQSLADIVQHLVNHGTHHRGQMSAALTALGQPAPLLDYIYFLPQRQDTR
>FNEC01000005.1|SDI43988.1|68297_68714_-|hypothetical-protein
MRLATRVSCAVLSAALLSQLAACGTLFYPDRRGQIDGRIDPAIAVFDAIGLLFYIIPGLIAFGVDFATGAIYLPDEKYSVAPEKLHEAVGADGQVDRTKLKAIIERETGRALPLDDPRLIQRVGNPQQLASLGLKLEG

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Crispr_ID: FNEC01000005_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

FNEC01000005_3

59435-59710

TypeI-E

I-E

Consensus_repeat	Method
GGCCTAGTAGCGGTGTTCCCCGCAGGTGCGGGGATGAACCG	PILER-CR
GTGTTCCCCGCAGNTGCGGGGATGAACCG	CRT

4 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of FNEC01000005_3

>merge|FNEC01000005|3|59435-59710|PILER-CR,CRT
CGGTGTTCCCCGCAGATGCGGGGATGAACCGGCGACGAGTCCGGATGTCTTGGCCTAGTCGCGGTGTTCCCCGCAGGTGCGGGGATGAACCGTCGCGGCGGGCCGCCAGCCAGGCCTTGTAGGCGTGTTCCCCGCAGGTGCGGGGATGAACCGATTGATCTCGCGGGTCTCGTAGTCCACGGCCCCGTGTTCCCCGCAGGTGTGGAGATGAACCGAACAACAAGTTGCTCGTTCGCCCCGTCCGTAGGTATTCCCCGCGTATGCGGGGATGTGCCG

>FNEC01000005|3|3|59435-59587|PILER-CR
CGGTGTTCCCCGCAGATGCGGGGATGAACCGGCGACGAGTC	CGGATGTCTTGGCCTAGTCG
CGGTGTTCCCCGCAGGTGCGGGGATGAACCGTCGCGGCGGG	CCGCCAGCCAGGCCTTGTAG
GCGTGTTCCCCGCAGGTGCGGGGATGAACCG

>FNEC01000005|3|3|59437-59710|CRT
GTGTTCCCCGCAGATGCGGGGATGAACCG	GCGACGAGTCCGGATGTCTTGGCCTAGTCGCG
GTGTTCCCCGCAGGTGCGGGGATGAACCG	TCGCGGCGGGCCGCCAGCCAGGCCTTGTAGGC
GTGTTCCCCGCAGGTGCGGGGATGAACCG	ATTGATCTCGCGGGTCTCGTAGTCCACGGCCCC
GTGTTCCCCGCAGGTGTGGAGATGAACCG	AACAACAAGTTGCTCGTTCGCCCCGTCCGTAG
GTATTCCCCGCGTATGCGGGGATGTGCCG

Protein	Signature genes	Signature genes Name	Protein_function
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
FNEC01000005.1\|SDI43836.1\|64824_65304_-\|transcriptional-regulator,-AsnC-family	unknown	unknown	gnl\|CDD\|224439
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
FNEC01000005.1\|SDI43882.1\|65747_66896_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369035
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	unknown	unknown	gnl\|CDD\|236222
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	unknown	unknown	gnl\|CDD\|224228
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842
FNEC01000005.1\|SDI43988.1\|68297_68714_-\|hypothetical-protein	unknown	unknown	unknown
FNEC01000005.1\|SDI43765.1\|63583_64192_+\|ribosomal-large-subunit-pseudouridine-synthase-E	unknown	unknown	gnl\|CDD\|211334
FNEC01000005.1\|SDI43804.1\|64199_64403_-\|Protein-of-unknown-function	unknown	unknown	gnl\|CDD\|378526
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|235387
FNEC01000005.1\|SDI43734.1\|62441_63488_-\|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily	unknown	unknown	gnl\|CDD\|293841
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|237559
FNEC01000005.1\|SDI43917.1\|66888_67779_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|181919
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
FNEC01000005.1\|SDI43950.1\|67780_68296_-\|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)	unknown	unknown	gnl\|CDD\|225200
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|183199

Protein	Function_ID	Function_description	E-value
FNEC01000005.1\|SDI43631.1\|58506_58806_+\|CRISPR-associated-protein,-Cas2-family	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.07162e-62
FNEC01000005.1\|SDI43396.1\|50423_53108_+\|CRISPR-associated-helicase,-Cas3-family	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	3.17586e-105
FNEC01000005.1\|SDI43836.1\|64824_65304_-\|transcriptional-regulator,-AsnC-family	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	9.68709e-50
FNEC01000005.1\|SDI43496.1\|55199_56333_+\|CRISPR-associated-protein,-Cse4-family	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.86508e-153
FNEC01000005.1\|SDI43882.1\|65747_66896_+\|hypothetical-protein	gnl\|CDD\|369035	pfam06682, SARAF, SOCE-associated regulatory factor of calcium homoeostasis. SARAF is as family of eukaryotic proteins embedded in the ER. SARAF is SOCE-associated regulatory factor, where SOCE is store operated calcium entry. ie a mechanism governing calcium homoeostasis in the cell and the mitochondria. SOCE involves the enabling of Ca2+ release-activated Ca2+ (CRAC) channels. SARAF is a single pass ER membrane protein whose systolic-facing domain is responsible for activity and whose luminary-facing domain carries out a regulatory function in conjunction with another membrane protein STIM, an ER single pass membrane protein that detects changes in ER Ca2+ levels through its EF-hand, conserved Ca2+ binding domain. STIM is the major target for SARAF regulation, and thus SARAF negatively regulates the SOCE entry of calcium into cells protecting them from overfilling.	1.87483e-05
FNEC01000005.1\|SDI43665.1\|59813_61289_+\|AMP-nucleosidase	gnl\|CDD\|236222	PRK08292, PRK08292, AMP nucleosidase; Provisional.	0
FNEC01000005.1\|SDI43565.1\|56981_57593_+\|CRISPR-associated-protein,-Cse3-family	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	2.48592e-62
FNEC01000005.1\|SDI43326.1\|47481_48129_+\|transcriptional-regulator,-TetR-family	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.10046e-12
FNEC01000005.1\|SDI43529.1\|56335_57007_+\|CRISPR-associated-protein,-Cas5e-family	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	2.83359e-53
FNEC01000005.1\|SDI43765.1\|63583_64192_+\|ribosomal-large-subunit-pseudouridine-synthase-E	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	6.80296e-90
FNEC01000005.1\|SDI43804.1\|64199_64403_-\|Protein-of-unknown-function	gnl\|CDD\|378526	pfam10981, DUF2788, Protein of unknown function (DUF2788). This bacterial family of proteins have no known function.	1.51872e-11
FNEC01000005.1\|SDI43693.1\|61373_62132_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|235387	PRK05283, PRK05283, deoxyribose-phosphate aldolase; Provisional.	3.83916e-103
FNEC01000005.1\|SDI43734.1\|62441_63488_-\|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily	gnl\|CDD\|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	7.11378e-82
FNEC01000005.1\|SDI43460.1\|54666_55188_+\|CRISPR-associated-protein,-Cse2-family	gnl\|CDD\|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	2.67928e-51
FNEC01000005.1\|SDI43917.1\|66888_67779_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|181919	PRK09509, fieF, CDF family cation-efflux pump FieF.	2.6584e-112
FNEC01000005.1\|SDI43426.1\|53104_54670_+\|CRISPR-associated-protein,-Cse1-family	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	3.59692e-95
FNEC01000005.1\|SDI43603.1\|57637_58510_+\|CRISPR-associated-protein,-Cas1-family	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.02794e-147
FNEC01000005.1\|SDI43950.1\|67780_68296_-\|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	1.79022e-35
FNEC01000005.1\|SDI43364.1\|48125_49775_+\|putative-acyl-CoA-dehydrogenase	gnl\|CDD\|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	4.49385e-164

>FNEC01000005.1|SDI43631.1|58506_58806_+|CRISPR-associated-protein,-Cas2-family
MSFLVVVTENVPPRLRGRLAIWLLEVRAGVYIGDVSRRTREMIWQQLSEGHGDGNVVMAWASAHESGYEFQTLGPNRRLPVEFDGLRLVAFQPLDSPDL
>FNEC01000005.1|SDI43603.1|57637_58510_+|CRISPR-associated-protein,-Cas1-family
MIFIQYGQIDVLDGAFVVIDKSGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGESGVRLYASGQPGGARADRLLYQARLALDDELRLKVVRKMYELRFQEPAPARRSVEQLRGIEGARVRGTYKLLARQYGVDWRSRNYDHQQWDAADIPNRCLSAATACLYGITEAAVLAAGYAPAIGFIHTGKPLSFVYDVADLFKFETVVPLAFRIAAQSPPEPERAVRLACRDLFRSSKLLGRIIPSIEEVLAAGGISPPEAPPESVPPAIPNPEGIGEAGHRSQG
>FNEC01000005.1|SDI43565.1|56981_57593_+|CRISPR-associated-protein,-Cse3-family
MHLTRLRLDPRSAQARRDLGDAYEMHRTLVRAFVRDEQHSPPRILWRAEPTSAWSDPVVLVQAQEVADWSVLQALPNYLKGPVETRPLAPEQWLQEGERFRFRLFANPTVTREGKRLGLVAEDAQLAWLARQGERLGFSVEAALVTGSELLRSRKSEHRISLLRVCFEGRLQVRDPAALAQALRAGIGPGKAFGCGLLSLGRG
>FNEC01000005.1|SDI43529.1|56335_57007_+|CRISPR-associated-protein,-Cas5e-family
MATLLLRLQGPMQSWGTTSRFDERDTQLEPSKSGVLGLVCAALGRDRREPVDDLAALRMGVRVEREGVPMRDYQTATGVVIASSGKPDLDRTVVSPRYYLADAVFLVGLEGERALLADVHAALARPVWPLALGRKSFVPTSPVHLPEGLRDQSLEYALANCFCLLEGGTPRTPRRLLLEHPNEGSVRLDQPVAPFAERRFGPRFVKSALFTPGGAHAPDPTAA
>FNEC01000005.1|SDI43496.1|55199_56333_+|CRISPR-associated-protein,-Cse4-family
MSLFLEFHLIQNFAPSNLNRDDTGAPKDAIFGGQRRARVSSQCFKRAVRLAAKQHELLPEANRGIRTKKLKALLLERLAGRDAEEAGAKVEAALGAAGLKLKDDGKTEYLLFLGEGEVAAFAALIEQHWDELPVGGDKKSKKDAKASLPAEIIKKAKALLDGGKAVDVALFGRMLADMPAVNQDAACQVAHAISTHRVEREFDYFTAVDDKGDEGETGAGMIGQVEFNSATLYRYAVLDLRKLLGNLQEDRELALSAVEAFTRALALAIPTGKQNSFAAHNPPEFIGVCLRHASPLSLANAFERPVSPRADQALTEQSVERLTAYEDKLAPVYGAPQDRWLSLDLTDRWPADKGERLASLAALAQRARELAADALGA
>FNEC01000005.1|SDI43460.1|54666_55188_+|CRISPR-associated-protein,-Cse2-family
MSDHAEKFIEYLAALKDWDRGAMAALRHSLAFEPGAYPRAFPYVERFAGAAAHERDAHRLALYAVAGLFARHPLRRPQSFAAALGELLRLRQSPSIESRFVALLGADAENIVEYLRQAVSLLAADGIGFDHARLLVDLSQWLNPGTDPSRLRQRWARDFYRAAQPVSEYTDSE
>FNEC01000005.1|SDI43426.1|53104_54670_+|CRISPR-associated-protein,-Cse1-family
MNKDFCLLDEPWLLVRFADGRVEELGLLEVFARSGEIVALADTAPPNLVAHYRLLLAITHRALSEAFGRWREKDRARWFREGLPQAEIRGYLETWRERFWLFHPEQPFMQVAALATAEETRDKYKPWTQIALASASGNAPMVFDHACDLTPTAIRPALALATLLGFLQFTPGGLVKSLRDSDKAGALANTAAVLPLGENLAQTLCLALHPAPRNDAEPDLPTWERESPSIAALRGEPLLATGPNDRYTRLSRAVLLRREADGNVRWLHYAAGLALGEDPNAPDPMASFRAGSNGLVRLTFSEGRALWRDLPALVPHAGAGSQAAAVVQNAIGLHGNLAHFEPVHQPLLVAGLASDQAKLLRWRLERISLPSALLLEPDKALYLRGRLELAETLFLELRRLASGMLAETLPDPASKDTRARARSLVDAGPLAASYFAAAERALPELLDGIGAGALDEAESLWRGVLHRSAEAAWQQVLAGLGYSSRALRADARYWPRFRGLLKAQLAISDDPTIDVDKEAMS
>FNEC01000005.1|SDI43396.1|50423_53108_+|CRISPR-associated-helicase,-Cas3-family
MGEGRLSFSGLSAAGRAVWAKSGDEGGHGLLAHLLDVAAVAETLLEIEPASTRRWASRALGVDEAEVGRWVAAIAGLHDFGKAIPGFQAKWPDGMAADQAHGLAFPASACNQGRHDLATASLLGRALLGVVAIEAGWLRDAVQAVSAHHGYHFLPDETNQGRPLAEPATWPAVRDEILRGYWQVLAPNGAPALDELSLPAVNWLAGLTSAADWIASNPEWFVPDQRGFDDLADYFRNACRLARLAFSQIGWRPYRPLLAGPADTDAVLARIVGRPGLSARPLQRVGDQLLQGVRGPALVVVEAPMGEGKTEFAFLAHLRLQAANGHRGLYVALPTQATGNALFDRALTFLEQFTTGPLDVQLVHGGAGMNEQVRHLRGIDHSSAESLSASAWFSQRKRPLLSAYGVGTIDQALFAALNVKHHFVRLWGLANRVVVLDEVHAYDTYTSGLIAALLRWLKALGCSVVLMSATLPLGRRAELLRAWGVSPDQVPELDYPRLLVADEGGIQGEHFGARPQSSIRLAGLDESLDTLADTAVELLAGGGCGALIVNTVERAQKLYIGLRQRLGDEVPLLLFHARFPADERAEREREVLAAFGTQGDRPRRALLVATQVAEQSLDIDFDFMLSDLAPVDLLLQRAGRLHRHDRERPAKHVQACLWVAGLRNGELPELENTAWRHVYDAYILLRTWALLRDGESLSLPADIDRLVQAVYGDDPLPDGLEEKARALIEIESYGEYLARVQKERRESFNIAIDPAEEPRSAYNGKPRGSEEGEGVGLENRTRLGPESITLIPVEEVEGGWCVRPGEPSFDPARPLDDAQARRLYERQLKVSRRALVAHFKRIDLPAAFEHPLLRNCYPLPLRQGQYPGEGLSLRLDSVLGLVYGPVDGANEGMA
>FNEC01000005.1|SDI43364.1|48125_49775_+|putative-acyl-CoA-dehydrogenase
MNLHQYAETHEVSNQVPPLDGANLYRVDLPLQEWLRRYDGGWAEARLDAYGALAGGPLMAAGFLANENKPVFKSHDRYGHRIDLVEFHPAYHELMRTAIEHGIPSMPWTDPRAGAHVARAGLSYLHSQAEAGTGCPLTMTFASVPAIRLQPDIAEKWLPKILATEYDPRNLPIEQKAGATIGMAMTEKQGGTDVRANTTRAYPVGIPGPGQAYELVGHKWFCSAPMCDAFLTLAYTDKGLTCFLLPRHRPDGTRNEFYVQRLKNKLGNWSNASSEVEYRGALAWMVGEEGRGVPTIIEMVAMTRFDCMVGSSALMRQALTQAAHHCAYRQVGGRVLAEQPLMQNVLADLALESEAALALTMRMGRALDHLHDEQEDKFARLVTAVGKYWICKRAPAMINEAAECLGGAGYVEDTILPRLYREAPVNSTWEGSGNVQCLDVLRALSKEPGVLDALFAELGDGHGDARLAAFIGNLKASFADTADIQFRARQLTEDVAVALQAKLLLEAGNATVADAFIGSRLGNGGRVYGTLPRGTDVEALVARATPHLA
>FNEC01000005.1|SDI43326.1|47481_48129_+|transcriptional-regulator,-TetR-family
MVYRLTEARLQKDVELRERILQLALARVAEGGFAALTMQGLAEEAGIATGSLYRHFRGKGELAAEVFARASQREVDALAVVLRGTGGPAGRLARGLRQFARRAWDSRRLAFALIAEPVDPEVDEQRLLYREAYAELFGELLEEGVRSGHFHCGPTSLIAACLVGAIAESLVGPLSPPARAARDAGQPSPGLEQVSQALVDFCLRAVGAPQPEEPR
>FNEC01000005.1|SDI43665.1|59813_61289_+|AMP-nucleosidase
MNAELGDAFVVAHTAEEAVDRLAALHQRATGALSQALRRYLKTREQPAAEERALFRYPLLRLSYLCQGEVPSTTRAYAKVQTPGNYAVTITHPEAFRKYLLEQLRPLMEDFTVRVEVGPSEQNIPYPYVVEQGDELAGSGVTAAELARVFPSTDLSATSDGIADGLYQWEGADPMPLALFDAARTDFSLRRLVHYTGSDWRCVQPWILLTNYHRYVDQFIHMGLERLHEDPRFVRMVLPGNVVIERDMDRGEANAIIAGVEWHRFQMPAYHLIASDGDGVTLINIGVGPSNAKNITDHLAVLRPHCWLMIGHCGGLRQSQTIGDYVLAHAYMRRDGILDRVLPPHIPIPALAEVQVALQEAAALVTGERGEALKRRLRTGTVLTYDDRNWELHWAQERPLINLARAVAVDMESGTIAAQGYRLRVPYGTLLCVSDKPLHSEIKLPGAASAFYQRAVSQHLAIGIAAVDLLRTQLNSLHSRKLRSFDEPPFR
>FNEC01000005.1|SDI43693.1|61373_62132_+|deoxyribose-phosphate-aldolase
MAEPLQPTRAERAARLLSLLDLTSLNADDDMPRIVQLCRRALTPYGEVAAVCVYPRFVHVARRTLNGFGARAVKVASVCNFPAGDAPLAEVVEEVRRTLAEGADEIDLVYPWQALKAGRADGAVELIRACKALCGPYHRLKVIIESGELAEPELIRTACREAIAGGADFLKSSTGKVAVNATPEAARVMLECIVETGGKVGFKVAGGIRSLDDAEVYLAIAQEMLGDDWITSEHLRFGASALLDELLREMEA
>FNEC01000005.1|SDI43734.1|62441_63488_-|L-ascorbate-metabolism-protein-UlaG,-beta-lactamase-superfamily
MPKARRSPWLITLLNLAGRLGGGYRGPQNTNFDGLRFRNLDAKPHHGFREFLKWQLERDRQLAWIEQPGPERRPETPARVSGEELRVTYVNHATLLIQHRGLNILTDPLWCERTSPFSFVGPKRHHPPGLALDELPPINLILVSHNHYDHLDVGSLGELARRFPQAKVVTGLGNAELIRACGFVEVHELDWWQSLPLHEGMRLTGVPAQHWSARSRYDTNRTLWLGFVLESADGPVLFPGDTGLGPEFGLIRERFGPMRFAALPIGAYEPRWFMRHHHMNPDDAVQAHRTLESQCSMAIHFGTFRLSDEGQFAPVHDLARALDEQGVDSQAFRAPKPGEQWLVGRMGG
>FNEC01000005.1|SDI43765.1|63583_64192_+|ribosomal-large-subunit-pseudouridine-synthase-E
MPRPPRPAPRRPAPRRVAKAPPAQPRLILLNKPFDVLTQFSDGEGRATLKDYVPVPGVYPAGRLDHDSEGLLLLTNDGRLQARIADPRHKLPKTYWVQVEGEPDEEQLQRLREGVQLNDGPTLPAEARRIDEPRLWERVPPVRFRKSVPTAWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWGLDGLQPGEWREVQP
>FNEC01000005.1|SDI43804.1|64199_64403_-|Protein-of-unknown-function
MNESFEDWMMYGLVSALVLFMAFIVWDLAKKSKAGRMGTMVLFFALGLGVFGFLVKSFVVAGLEGGF
>FNEC01000005.1|SDI43836.1|64824_65304_-|transcriptional-regulator,-AsnC-family
MNKLDRYDLRILAELQRDARISNQELAERIGLSPSPCSRRVKQLEDDGYILRQVALLDSKKLGLSLTAFVLIGMDRHTPERFEHFQSIIAQCPEVLECSLVTGMDADYQLKVMVPDMEHYQHFLLGTLTRIEGVTSVRSSFVLRNIMASTELPLEHLRS
>FNEC01000005.1|SDI43882.1|65747_66896_+|hypothetical-protein
MKSGIWCLASVGLLSLAIAGQAFAEGQGPGHGGQGGHGGGNGGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGNQGGQWQGRPQGSQASQGQGRPQNNWNGQWQGRPSHDDRGPDHRPGNWTTQWSSPSQGGGNGRGSDRRPGDWTTQWPGLNHGDRDDHGPGRPSAGGGSWQGRPPSAPGNAWHGRPGGNWGPHPSNWRPGYVVDRVPSGYYRVPWRGSDYFFNDGYWYRPHGARYVVVTPPYGVRVSYLPSYAEQLWFGSMLYFLAAGTYYLFDNSSQTYEVVPPPPQVAQAPLPTGNPYDVIAYPMYGQSPQQQAQDHYECHTWAVGQSGFDPAMAGYAPSQQAVDAYRGALGSCMQGRGYSVN
>FNEC01000005.1|SDI43917.1|66888_67779_-|cation-diffusion-facilitator-family-transporter
MDKDRARLLRLATSASLAVAVILVVTKALAWWYSGSVSLLAGLTDSLLDGAASLLNLLAVRYALRPADEDHRYGHGKAESLSGMGQALFISVSAVLIGTQALDRLQHPEPLGATGWGILVMLLSLALTVALLALQRRVIKRTGSLAVQADSLHYRSDLLLNGSILVALLLAHYGFPRMDAVFGLGIAAYILWSAVRIARESVAVLMDEELPADVSERMLELVRQVPGVAGAHDLRTRISGDRWFVQLHLELPGDMRLSQAHALCDQAVLAIRAEFPRAEVLVHADPLEVVGRETIS
>FNEC01000005.1|SDI43950.1|67780_68296_-|Uncharacterized-damage-inducible-protein-DinB-(forms-a-four-helix-bundle)
MHAVLGRHLEKLLDYHLWAHERILEAVAPLDEAAYREPRGLFFGSLHGTLNHLAVVDRIWLDRVAGRPWQFTRLDTEAAPDRAALADFLREGVQGWKQWLARQDERDLGKQLEYRNMAGQEHRQSLADIVQHLVNHGTHHRGQMSAALTALGQPAPLLDYIYFLPQRQDTR
>FNEC01000005.1|SDI43988.1|68297_68714_-|hypothetical-protein
MRLATRVSCAVLSAALLSQLAACGTLFYPDRRGQIDGRIDPAIAVFDAIGLLFYIIPGLIAFGVDFATGAIYLPDEKYSVAPEKLHEAVGADGQVDRTKLKAIIERETGRALPLDDPRLIQRVGNPQQLASLGLKLEG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
FNEC01000005_3	3.2\|59537\|20\|FNEC01000005\|PILER-CR	59537-59556	20	FNEC01000001.1	56752-56771	2	0.9

1. spacer 3.2|59537|20|FNEC01000005|PILER-CR matches to position: 56752-56771, mismatch: 2, identity: 0.9

tcgcggcgggccgccagcca	CRISPR spacer
tcggcgcgggccgccagcca	Protospacer
***  ***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
FNEC01000005_3	3.2\|59537\|20\|FNEC01000005\|PILER-CR	59537-59556	20	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	593191-593210	1	0.95
FNEC01000005_3	3.2\|59537\|20\|FNEC01000005\|PILER-CR	59537-59556	20	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1874822-1874841	1	0.95
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_LR134420	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 11	168548-168579	6	0.812
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NC_007353	Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence	18505-18536	7	0.781
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	130937-130968	7	0.781
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NC_019369	Burkholderia cepacia plasmid pYS1, complete sequence	31744-31775	7	0.781
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	MN310542	Mycobacterium phage Keziacharles14, complete genome	17178-17209	7	0.781
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	NZ_CP030764	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence	40318-40347	7	0.767
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	978624-978653	7	0.767
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP016024	Ralstonia insidiosa strain ATCC 49129 plasmid pRI-1, complete sequence	153345-153376	7	0.781
FNEC01000005_1	1.1\|49868\|32\|FNEC01000005\|PILER-CR,CRT	49868-49899	32	NC_014840	Pantoea sp. At-9b plasmid pPAT9B03, complete sequence	70300-70331	8	0.75
FNEC01000005_1	1.3\|49990\|32\|FNEC01000005\|PILER-CR,CRT	49990-50021	32	KT339177	Lactococcus phage GE1, complete genome	11732-11763	8	0.75
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1365128-1365159	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	539732-539763	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP014675	Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence	370-401	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_LT900339	Gluconobacter oxydans 621H isolate WT-DSMZ plasmid 2	157621-157652	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NC_006672	Gluconobacter oxydans 621H plasmid pGOX1, complete sequence	157620-157651	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP015167	Acetobacter ascendens strain LMG 1590 plasmid unnamed3, complete sequence	5996-6027	8	0.75
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP043044	Gluconobacter thailandicus strain HD924 plasmid unnamed1, complete sequence	102086-102117	8	0.75
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	631043-631072	8	0.733
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	MF417841	Uncultured Caudovirales phage clone 7S_11, partial genome	6037-6066	8	0.733
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	371837-371868	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1874822-1874853	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	675570-675601	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NC_012849	Ralstonia pickettii 12D plasmid pRp12D02, complete sequence	168254-168285	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	402679-402710	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_AP018687	Vibrio rumoiensis strain FERM P-14531 plasmid 1, complete sequence	45433-45464	8	0.75
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	KY697807	Microcystis phage MACPNOA1, complete genome	2497-2528	8	0.75
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_KJ599675	Micrococcus sp. A7 plasmid pLMA7, complete sequence	54479-54510	9	0.719
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP029209	Nitratireductor sp. OM-1 plasmid pOM-1, complete sequence	555508-555539	9	0.719
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP041043	Paracoccus sp. AK26 plasmid pAK3, complete sequence	70765-70796	9	0.719
FNEC01000005_1	1.6\|50173\|32\|FNEC01000005\|CRT	50173-50204	32	NC_001884	Bacillus phage SPBc2, complete genome	61109-61140	9	0.719
FNEC01000005_1	1.6\|50173\|32\|FNEC01000005\|CRT	50173-50204	32	AF020713	Bacteriophage SPBc2 complete genome	61109-61140	9	0.719
FNEC01000005_1	1.6\|50173\|32\|FNEC01000005\|CRT	50173-50204	32	MT366948	Bacillus phage Hyb3phi3Ts-SPbeta, complete genome	50598-50629	9	0.719
FNEC01000005_1	1.6\|50173\|32\|FNEC01000005\|CRT	50173-50204	32	MT601274	Bacillus phage vB_BsuS-Goe13, complete genome	51305-51336	9	0.719
FNEC01000005_1	1.6\|50173\|32\|FNEC01000005\|CRT	50173-50204	32	MT601273	Bacillus phage vB_BsuS-Goe12, complete genome	51305-51336	9	0.719
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	NZ_CP013412	Burkholderia thailandensis strain 2002721643 plasmid p2002721643, complete sequence	107066-107095	9	0.7
FNEC01000005_2	2.7\|59087\|30\|FNEC01000005\|PILER-CR	59087-59116	30	NZ_CP010016	Burkholderia thailandensis 34 plasmid unnamed, complete sequence	324576-324605	9	0.7
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP015420	Rhodovulum sulfidophilum DSM 1374 plasmid unnamed2, complete sequence	50675-50706	9	0.719
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_AP014801	Rhodovulum sulfidophilum plasmid Plasmid1 DNA, complete genome, strain: DSM 2351	35492-35523	9	0.719
FNEC01000005_3	3.6\|59650\|32\|FNEC01000005\|CRT	59650-59681	32	NZ_AP014883	Acetobacter pasteurianus NBRC 101655 plasmid plasmid2 DNA, complete genome	4558-4589	9	0.719
FNEC01000005_1	1.1\|49868\|32\|FNEC01000005\|PILER-CR,CRT	49868-49899	32	NZ_CP033873	Caulobacter sp. FWC26 plasmid p1, complete sequence	155472-155503	10	0.688
FNEC01000005_1	1.1\|49868\|32\|FNEC01000005\|PILER-CR,CRT	49868-49899	32	NZ_AP022320	Burkholderia sp. THE68 plasmid BTHE68_p2, complete sequence	49886-49917	10	0.688
FNEC01000005_1	1.1\|49868\|32\|FNEC01000005\|PILER-CR,CRT	49868-49899	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1745477-1745508	10	0.688
FNEC01000005_1	1.3\|49990\|32\|FNEC01000005\|PILER-CR,CRT	49990-50021	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2991031-2991062	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	581781-581812	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP025017	Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence	233775-233806	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	569467-569498	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	179118-179149	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP054026	Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence	274763-274794	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP054036	Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence	116215-116246	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	598645-598676	10	0.688
FNEC01000005_1	1.4\|50051\|32\|FNEC01000005\|PILER-CR,CRT	50051-50082	32	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	350954-350985	10	0.688
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	53983-54014	10	0.688
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NZ_CP046330	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence	19666-19697	10	0.688
FNEC01000005_1	1.5\|50112\|32\|FNEC01000005\|CRT	50112-50143	32	NC_006525	Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence	87022-87053	10	0.688
FNEC01000005_3	3.3\|59466\|32\|FNEC01000005\|CRT	59466-59497	32	NZ_CP029434	Klebsiella quasipneumoniae strain CAV2013 plasmid pCAV2013-61, complete sequence	6826-6857	10	0.688
FNEC01000005_3	3.3\|59466\|32\|FNEC01000005\|CRT	59466-59497	32	NZ_CP029428	Klebsiella quasipneumoniae strain CAV2018 plasmid pCAV2018-51, complete sequence	1758-1789	10	0.688
FNEC01000005_3	3.3\|59466\|32\|FNEC01000005\|CRT	59466-59497	32	NZ_CP029440	Klebsiella quasipneumoniae strain CAV1947 plasmid pCAV1947-61, complete sequence	54812-54843	10	0.688
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NZ_CP020385	Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence	129236-129267	10	0.688
FNEC01000005_3	3.4\|59527\|32\|FNEC01000005\|CRT	59527-59558	32	NC_016972	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG2, complete sequence	64412-64443	11	0.656

1. spacer 3.2|59537|20|FNEC01000005|PILER-CR matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 1, identity: 0.95

tcgcggcgggccgccagcca	CRISPR spacer
gcgcggcgggccgccagcca	Protospacer
 *******************

2. spacer 3.2|59537|20|FNEC01000005|PILER-CR matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 1, identity: 0.95

tcgcggcgggccgccagcca	CRISPR spacer
tcgcggcgggccgccagccg	Protospacer
*******************.

3. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_LR134420 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 11) position: , mismatch: 6, identity: 0.812

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
tttaccagctcggcatgcccctcctgggcagc	Protospacer
**.  **********.****** ******* *

4. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NC_007353 (Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence) position: , mismatch: 7, identity: 0.781

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
gcttcgcgcaccggggccgcgaactggacggc	Protospacer
**.* * .*********  ************

5. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

gcctggaacaccggggcgccgaactggacgga--	CRISPR spacer
gccaggaacaccgaggcgccgaa--ggtcgcctt	Protospacer
*** *********.*********  ** **

6. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NC_019369 (Burkholderia cepacia plasmid pYS1, complete sequence) position: , mismatch: 7, identity: 0.781

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
gcttcgcgcaccggggccgcgaactggacggc	Protospacer
**.* * .*********  ************

7. spacer 1.5|50112|32|FNEC01000005|CRT matches to MN310542 (Mycobacterium phage Keziacharles14, complete genome) position: , mismatch: 7, identity: 0.781

ttctgca-gctcggcacgcccctgctgggcatc	CRISPR spacer
-ccgacacgctcggcacgctcctggtgggcaac	Protospacer
 .* .** ***********.**** ****** *

8. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to NZ_CP030764 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

caggacgctgatgacggtccagccgatgat	CRISPR spacer
cttcatgtcgatgacggtccagccggtgat	Protospacer
*   *.*..****************.****

9. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 7, identity: 0.767

caggacgctgatgacggtccagccgatgat	CRISPR spacer
gaggccgctgatgacggtcgagcccgttgt	Protospacer
 *** ************** **** .* .*

10. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP016024 (Ralstonia insidiosa strain ATCC 49129 plasmid pRI-1, complete sequence) position: , mismatch: 7, identity: 0.781

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
aggccggacgccgccagccaggcctcgtaggc	Protospacer
  ** * . ****************.******

11. spacer 1.1|49868|32|FNEC01000005|PILER-CR,CRT matches to NC_014840 (Pantoea sp. At-9b plasmid pPAT9B03, complete sequence) position: , mismatch: 8, identity: 0.75

actccttgcgggtgcgctcttgcttgcgctta	CRISPR spacer
gctggtggcgggtgcgctgttgattgcgctgg	Protospacer
.**  * *********** *** ******* .

12. spacer 1.3|49990|32|FNEC01000005|PILER-CR,CRT matches to KT339177 (Lactococcus phage GE1, complete genome) position: , mismatch: 8, identity: 0.75

gttttcttcggagcttccatgtcggtcgtggc	CRISPR spacer
agtttcttaggagcttccatatcggctttgga	Protospacer
. ****** ***********.****.. ***

13. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 8, identity: 0.75

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
acctggaaaaccggggcgccaaacatggctgg	Protospacer
.******* ***********.***  *.* *.

14. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.75

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
aggcgcagcccggcacgcccctgctgggacgc	Protospacer
   .*****.******************   *

15. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP014675 (Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence) position: , mismatch: 8, identity: 0.75

ttctgcag----ctcggcacgcccctgctgggcatc	CRISPR spacer
----gtggctttctcggcatgccactgctgggcatc	Protospacer
    *..*    *******.*** ************

16. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_LT900339 (Gluconobacter oxydans 621H isolate WT-DSMZ plasmid 2) position: , mismatch: 8, identity: 0.75

ttctgcag----ctcggcacgcccctgctgggcatc	CRISPR spacer
----gtggctttctcggcatgccactgctgggcatc	Protospacer
    *..*    *******.*** ************

17. spacer 1.5|50112|32|FNEC01000005|CRT matches to NC_006672 (Gluconobacter oxydans 621H plasmid pGOX1, complete sequence) position: , mismatch: 8, identity: 0.75

ttctgcag----ctcggcacgcccctgctgggcatc	CRISPR spacer
----gtggctttctcggcatgccactgctgggcatc	Protospacer
    *..*    *******.*** ************

18. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP015167 (Acetobacter ascendens strain LMG 1590 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

ttctgcag----ctcggcacgcccctgctgggcatc	CRISPR spacer
----gtggctttctcggcatgccactgctgggcatc	Protospacer
    *..*    *******.*** ************

19. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP043044 (Gluconobacter thailandicus strain HD924 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttctgcag----ctcggcacgcccctgctgggcatc	CRISPR spacer
----gtggctttctcggcatgccactgctgggcatc	Protospacer
    *..*    *******.*** ************

20. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 8, identity: 0.733

caggacgctgatgacggtccagccgatgat	CRISPR spacer
gatacggctgatgacgggcctgccgatgaa	Protospacer
 * .  *********** ** ********

21. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to MF417841 (Uncultured Caudovirales phage clone 7S_11, partial genome) position: , mismatch: 8, identity: 0.733

caggacgctgatgacggtccagccgatgat	CRISPR spacer
ttgctcgctgatgacggtcccgcggatggg	Protospacer
. *  *************** ** ****.

22. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gcgcggtcggccgccagccaggcctcgatgat	Protospacer
 *****. *****************.*  *..

23. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
tcgcggcgggccgccagccggaccgtcgaaag	Protospacer
*******************.*.** *  *..

24. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gcgcggtcggccgccagccaggcctcgatgat	Protospacer
 *****. *****************.*  *..

25. spacer 3.4|59527|32|FNEC01000005|CRT matches to NC_012849 (Ralstonia pickettii 12D plasmid pRp12D02, complete sequence) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
aggccggacgccgccaaccaggcctcgtaggc	Protospacer
  ** * . *******.********.******

26. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
tccgggtgggccgccagccaggccgtgacgtg	Protospacer
**  **.***************** **  *

27. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_AP018687 (Vibrio rumoiensis strain FERM P-14531 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

tcgc-ggcgggccgccagccaggccttgtaggc	CRISPR spacer
-cgcgggcggcccgccaaccaggccttgacctt	Protospacer
 *** ***** ******.**********    .

28. spacer 3.4|59527|32|FNEC01000005|CRT matches to KY697807 (Microcystis phage MACPNOA1, complete genome) position: , mismatch: 8, identity: 0.75

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
cagccgcgcgccgccagccaggcctcgaactc	Protospacer
. ** *** ****************.* *  *

29. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_KJ599675 (Micrococcus sp. A7 plasmid pLMA7, complete sequence) position: , mismatch: 9, identity: 0.719

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
agggcgcgcaccggggcgccaagctggacgga	Protospacer
.    * .************.*.*********

30. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP029209 (Nitratireductor sp. OM-1 plasmid pOM-1, complete sequence) position: , mismatch: 9, identity: 0.719

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
ctgttctacacctggacgccgaactggacggt	Protospacer
 . *   ***** **.***************

31. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP041043 (Paracoccus sp. AK26 plasmid pAK3, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
tgatcgcgcccggcacgccgctgctgggcaag	Protospacer
*  *   **.********* **********

32. spacer 1.6|50173|32|FNEC01000005|CRT matches to NC_001884 (Bacillus phage SPBc2, complete genome) position: , mismatch: 9, identity: 0.719

tcataatcagcttcctcctaagtg--agcaggtt	CRISPR spacer
tcataatcaatttcctcctaagtattattaaa--	Protospacer
*********..************.  * .*..

33. spacer 1.6|50173|32|FNEC01000005|CRT matches to AF020713 (Bacteriophage SPBc2 complete genome) position: , mismatch: 9, identity: 0.719

tcataatcagcttcctcctaagtg--agcaggtt	CRISPR spacer
tcataatcaatttcctcctaagtattattaaa--	Protospacer
*********..************.  * .*..

34. spacer 1.6|50173|32|FNEC01000005|CRT matches to MT366948 (Bacillus phage Hyb3phi3Ts-SPbeta, complete genome) position: , mismatch: 9, identity: 0.719

tcataatcagcttcctcctaagtg--agcaggtt	CRISPR spacer
tcataatcaatttcctcctaagtattattaaa--	Protospacer
*********..************.  * .*..

35. spacer 1.6|50173|32|FNEC01000005|CRT matches to MT601274 (Bacillus phage vB_BsuS-Goe13, complete genome) position: , mismatch: 9, identity: 0.719

tcataatcagcttcctcctaagtg--agcaggtt	CRISPR spacer
tcataatcaatttcctcctaagtattattaaa--	Protospacer
*********..************.  * .*..

36. spacer 1.6|50173|32|FNEC01000005|CRT matches to MT601273 (Bacillus phage vB_BsuS-Goe12, complete genome) position: , mismatch: 9, identity: 0.719

tcataatcagcttcctcctaagtg--agcaggtt	CRISPR spacer
tcataatcaatttcctcctaagtattattaaa--	Protospacer
*********..************.  * .*..

37. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to NZ_CP013412 (Burkholderia thailandensis strain 2002721643 plasmid p2002721643, complete sequence) position: , mismatch: 9, identity: 0.7

caggacgctgatgacggtccagccgatgat	CRISPR spacer
gtagtcgctgacgacggtccagccgagcgc	Protospacer
  .* ******.**************  ..

38. spacer 2.7|59087|30|FNEC01000005|PILER-CR matches to NZ_CP010016 (Burkholderia thailandensis 34 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

caggacgctgatgacggtccagccgatgat	CRISPR spacer
gtagtcgctgacgacggtccagccgagcgc	Protospacer
  .* ******.**************  ..

39. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP015420 (Rhodovulum sulfidophilum DSM 1374 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gcgccgctggccgccagccaggccgcgccttc	Protospacer
 *** ** **************** .*.   *

40. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_AP014801 (Rhodovulum sulfidophilum plasmid Plasmid1 DNA, complete genome, strain: DSM 2351) position: , mismatch: 9, identity: 0.719

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gcgccgctggccgccagccaggccgcgccttc	Protospacer
 *** ** **************** .*.   *

41. spacer 3.6|59650|32|FNEC01000005|CRT matches to NZ_AP014883 (Acetobacter pasteurianus NBRC 101655 plasmid plasmid2 DNA, complete genome) position: , mismatch: 9, identity: 0.719

aacaacaagttgctcgttcgccccgtccgtag	CRISPR spacer
gtttgctagttcatcgttcgccccgtccgtgg	Protospacer
. . .* ****  *****************.*

42. spacer 1.1|49868|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP033873 (Caulobacter sp. FWC26 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

actccttgcgggtgcgctcttgcttgcgctta	CRISPR spacer
ccaatggtcgcgtgcgctctggcttgcgcttc	Protospacer
 *  .   ** ********* **********

43. spacer 1.1|49868|32|FNEC01000005|PILER-CR,CRT matches to NZ_AP022320 (Burkholderia sp. THE68 plasmid BTHE68_p2, complete sequence) position: , mismatch: 10, identity: 0.688

actccttgcgggtgcgctcttgcttgcgctta	CRISPR spacer
ggtatgcacggttgcgctcttgcttgagcttg	Protospacer
. * . ..*** ************** ****.

44. spacer 1.1|49868|32|FNEC01000005|PILER-CR,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 10, identity: 0.688

actccttgcgggtgcgctcttgcttgcgctta	CRISPR spacer
ggtatgcacggttgcgctcttgcttgagcttg	Protospacer
. * . ..*** ************** ****.

45. spacer 1.3|49990|32|FNEC01000005|PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

gttttcttcggagcttccatgtcggtcgtggc	CRISPR spacer
ggcgcgttcggagcgtcgatgtcggtcgtcat	Protospacer
* . . ******** ** *********** ..

46. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggattagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

47. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP025017 (Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggatcagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

48. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggattagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

49. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
atggagaacaccgaggcgccgaacaggatgat	Protospacer
..  .********.********** ***.*.

50. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP054026 (Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggatcagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

51. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP054036 (Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggatcagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

52. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggattagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

53. spacer 1.4|50051|32|FNEC01000005|PILER-CR,CRT matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 10, identity: 0.688

gcctggaacaccggggcgccgaactggacgga	CRISPR spacer
aggatcagcacccgggcgccgaagtggacggc	Protospacer
.     *.**** ********** *******

54. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
aagtgcagctgggcacgcgcctgctgcagcgc	Protospacer
   ******* ******* ******* .   *

55. spacer 1.5|50112|32|FNEC01000005|CRT matches to NZ_CP046330 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
gccagcagctcggcatgccccagctggatcgt	Protospacer
 .* ***********.***** *****..  .

56. spacer 1.5|50112|32|FNEC01000005|CRT matches to NC_006525 (Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence) position: , mismatch: 10, identity: 0.688

ttctgcagctcggcacgcccctgctgggcatc	CRISPR spacer
gccagcagctcggcatgccccagctggatcgt	Protospacer
 .* ***********.***** *****..  .

57. spacer 3.3|59466|32|FNEC01000005|CRT matches to NZ_CP029434 (Klebsiella quasipneumoniae strain CAV2013 plasmid pCAV2013-61, complete sequence) position: , mismatch: 10, identity: 0.688

gcgacgagtccggatgtcttggcctagtcgcg	CRISPR spacer
tggacgagttcggatgtgttggcctgaaaatg	Protospacer
  *******.******* *******..  ..*

58. spacer 3.3|59466|32|FNEC01000005|CRT matches to NZ_CP029428 (Klebsiella quasipneumoniae strain CAV2018 plasmid pCAV2018-51, complete sequence) position: , mismatch: 10, identity: 0.688

gcgacgagtccggatgtcttggcctagtcgcg	CRISPR spacer
tggacgagttcggatgtgttggcctgaaaatg	Protospacer
  *******.******* *******..  ..*

59. spacer 3.3|59466|32|FNEC01000005|CRT matches to NZ_CP029440 (Klebsiella quasipneumoniae strain CAV1947 plasmid pCAV1947-61, complete sequence) position: , mismatch: 10, identity: 0.688

gcgacgagtccggatgtcttggcctagtcgcg	CRISPR spacer
tggacgagttcggatgtgttggcctgaaaatg	Protospacer
  *******.******* *******..  ..*

60. spacer 3.4|59527|32|FNEC01000005|CRT matches to NZ_CP020385 (Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence) position: , mismatch: 10, identity: 0.688

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gcgccgctggccgccagccaggccgcaccatc	Protospacer
 *** ** **************** ... . *

61. spacer 3.4|59527|32|FNEC01000005|CRT matches to NC_016972 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG2, complete sequence) position: , mismatch: 11, identity: 0.656

tcgcggcgggccgccagccaggccttgtaggc	CRISPR spacer
gtgcggcgggccgccaccctggcctaccgact	Protospacer
 .************** ** *****  ... .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

10. FNEC01000014

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

14497 : 21036

Pseudomonas_phage(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDJ21493.1\|14497_15547_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	5.0e-109	56.6
SDJ21533.1\|15543_16140_-	anthranilate synthase, component II	A0A0P0IKJ1	Acinetobacter_phage	3.0e-71	62.1
SDJ21574.1\|17657_17831_-	Mu-like prophage protein Com	B5TK59	Pseudomonas_phage	3.1e-08	63.2
SDJ21617.1\|17841_18114_-	hypothetical protein	NA	NA	NA	NA
SDJ21660.1\|18143_18476_-\|holin	holin, hol family	B5TK61	Pseudomonas_phage	1.4e-20	51.0
SDJ21697.1\|18756_19248_-	Ribosomal protein S18 acetylase RimI	NA	NA	NA	NA
SDJ21742.1\|19296_19656_-	hypothetical protein	NA	NA	NA	NA
SDJ21778.1\|19673_19883_-	transcriptional regulator, TraR/DksA family	Q9ZXI6	Pseudomonas_virus	1.4e-07	46.3
SDJ21817.1\|20277_21036_+	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	A0A1B0Z078	Pseudomonas_phage	2.3e-71	58.3

DBSCAN-SWA_2

55837 : 66209

Caulobacter_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SDJ23361.1\|55837_57877_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.8e-75	40.3
SDJ23405.1\|57955_59803_+	RNA polymerase, sigma 70 subunit, RpoD	A0A2I7SAT0	Vibrio_phage	3.4e-36	32.6
SDJ23451.1\|59922_63657_+	periplasmic sensor diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	8.7e-23	35.5
SDJ23497.1\|63821_64112_-	transcriptional regulator, XRE family	NA	NA	NA	NA
SDJ23552.1\|64111_64426_-	hypothetical protein	NA	NA	NA	NA
SDJ23594.1\|64645_65050_-	Predicted nuclease of the RNAse H fold, HicB family	A0A0U4ISP5	Pseudomonas_phage	7.4e-61	87.1
SDJ23635.1\|65082_65265_-	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	A0A0R6PJD4	Moraxella_phage	1.1e-16	61.7
SDJ23694.1\|65723_66209_+	Prophage antirepressor	E8ZDN2	Streptococcus_phage	4.3e-07	26.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage