CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_GL454108	Enterococcus faecalis TX2137 Scfld165, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454104	Enterococcus faecalis TX2137 Scfld147, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454098	Enterococcus faecalis TX2137 Scfld116, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454112	Enterococcus faecalis TX2137 Scfld182, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454118	Enterococcus faecalis TX2137 Scfld204, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454138	Enterococcus faecalis TX2137 Scfld317, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454052	Enterococcus faecalis TX2137 Scfld8, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_GL454082	Enterococcus faecalis TX2137 Scfld74, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454144	Enterococcus faecalis TX2137 Scfld357, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454076	Enterococcus faecalis TX2137 Scfld60, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454087	Enterococcus faecalis TX2137 Scfld88, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454146	Enterococcus faecalis TX2137 Scfld362, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454113	Enterococcus faecalis TX2137 Scfld183, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454103	Enterococcus faecalis TX2137 Scfld137, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454151	Enterococcus faecalis TX2137 Scfld481, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454072	Enterococcus faecalis TX2137 Scfld45, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454140	Enterococcus faecalis TX2137 Scfld320, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454114	Enterococcus faecalis TX2137 Scfld185, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454124	Enterococcus faecalis TX2137 Scfld231, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454051	Enterococcus faecalis TX2137 Scfld6, whole genome shotgun sequence	1 crisprs	NA	0	2	0	0
NZ_GL454149	Enterococcus faecalis TX2137 Scfld387, whole genome shotgun sequence	0 crisprs	NA	0	0	0	2
NZ_GL454105	Enterococcus faecalis TX2137 Scfld150, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454125	Enterococcus faecalis TX2137 Scfld242, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454145	Enterococcus faecalis TX2137 Scfld358, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454109	Enterococcus faecalis TX2137 Scfld169, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454066	Enterococcus faecalis TX2137 Scfld35, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454091	Enterococcus faecalis TX2137 Scfld95, whole genome shotgun sequence	0 crisprs	cas3,csa3,WYL	0	0	0	0
NZ_GL454092	Enterococcus faecalis TX2137 Scfld97, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454153	Enterococcus faecalis TX2137 Scfld555, whole genome shotgun sequence	0 crisprs	DEDDh,csa3,DinG	0	0	1	0
NZ_GL454152	Enterococcus faecalis TX2137 Scfld514, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454148	Enterococcus faecalis TX2137 Scfld377, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454121	Enterococcus faecalis TX2137 Scfld217, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454095	Enterococcus faecalis TX2137 Scfld109, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454097	Enterococcus faecalis TX2137 Scfld114, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454083	Enterococcus faecalis TX2137 Scfld81, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454137	Enterococcus faecalis TX2137 Scfld315, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454122	Enterococcus faecalis TX2137 Scfld223, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454150	Enterococcus faecalis TX2137 Scfld425, whole genome shotgun sequence	1 crisprs	csn2,cas2,cas1,cas9	0	8	0	0
NZ_GL454099	Enterococcus faecalis TX2137 Scfld117, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454078	Enterococcus faecalis TX2137 Scfld62, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454070	Enterococcus faecalis TX2137 Scfld39, whole genome shotgun sequence	0 crisprs	WYL	0	0	0	0
NZ_GL454063	Enterococcus faecalis TX2137 Scfld31, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454111	Enterococcus faecalis TX2137 Scfld181, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454065	Enterococcus faecalis TX2137 Scfld34, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454062	Enterococcus faecalis TX2137 Scfld30, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454086	Enterococcus faecalis TX2137 Scfld87, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454084	Enterococcus faecalis TX2137 Scfld82, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454064	Enterococcus faecalis TX2137 Scfld33, whole genome shotgun sequence	0 crisprs	DinG	0	0	0	0
NZ_GL454139	Enterococcus faecalis TX2137 Scfld318, whole genome shotgun sequence	2 crisprs	NA	1	13	1	0
NZ_GL454075	Enterococcus faecalis TX2137 Scfld57, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454069	Enterococcus faecalis TX2137 Scfld38, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454093	Enterococcus faecalis TX2137 Scfld98, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454147	Enterococcus faecalis TX2137 Scfld367, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454123	Enterococcus faecalis TX2137 Scfld224, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454142	Enterococcus faecalis TX2137 Scfld335, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454054	Enterococcus faecalis TX2137 Scfld10, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454053	Enterococcus faecalis TX2137 Scfld9, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454107	Enterococcus faecalis TX2137 Scfld163, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454061	Enterococcus faecalis TX2137 Scfld29, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454071	Enterococcus faecalis TX2137 Scfld40, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454059	Enterococcus faecalis TX2137 Scfld19, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454090	Enterococcus faecalis TX2137 Scfld94, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454049	Enterococcus faecalis TX2137 Scfld4, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454129	Enterococcus faecalis TX2137 Scfld261, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454131	Enterococcus faecalis TX2137 Scfld278, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454050	Enterococcus faecalis TX2137 Scfld5, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454127	Enterococcus faecalis TX2137 Scfld247, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454088	Enterococcus faecalis TX2137 Scfld89, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454055	Enterococcus faecalis TX2137 Scfld11, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454056	Enterococcus faecalis TX2137 Scfld15, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454135	Enterococcus faecalis TX2137 Scfld296, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454102	Enterococcus faecalis TX2137 Scfld126, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454101	Enterococcus faecalis TX2137 Scfld124, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454106	Enterococcus faecalis TX2137 Scfld155, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454094	Enterococcus faecalis TX2137 Scfld99, whole genome shotgun sequence	1 crisprs	NA	0	0	0	0
NZ_GL454073	Enterococcus faecalis TX2137 Scfld50, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454079	Enterococcus faecalis TX2137 Scfld71, whole genome shotgun sequence	0 crisprs	cas3	0	0	1	0
NZ_GL454134	Enterococcus faecalis TX2137 Scfld292, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454115	Enterococcus faecalis TX2137 Scfld186, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454080	Enterococcus faecalis TX2137 Scfld72, whole genome shotgun sequence	0 crisprs	cas14j,cas3	0	0	2	0
NZ_GL454068	Enterococcus faecalis TX2137 Scfld37, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454119	Enterococcus faecalis TX2137 Scfld214, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454060	Enterococcus faecalis TX2137 Scfld26, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454116	Enterococcus faecalis TX2137 Scfld197, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454130	Enterococcus faecalis TX2137 Scfld263, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454057	Enterococcus faecalis TX2137 Scfld17, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454120	Enterococcus faecalis TX2137 Scfld216, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454143	Enterococcus faecalis TX2137 Scfld356, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454085	Enterococcus faecalis TX2137 Scfld86, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454089	Enterococcus faecalis TX2137 Scfld93, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454110	Enterococcus faecalis TX2137 Scfld175, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454074	Enterococcus faecalis TX2137 Scfld56, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454058	Enterococcus faecalis TX2137 Scfld18, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454077	Enterococcus faecalis TX2137 Scfld61, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454128	Enterococcus faecalis TX2137 Scfld253, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454096	Enterococcus faecalis TX2137 Scfld110, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454141	Enterococcus faecalis TX2137 Scfld330, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454048	Enterococcus faecalis TX2137 Scfld3, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454081	Enterococcus faecalis TX2137 Scfld73, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454100	Enterococcus faecalis TX2137 Scfld118, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454067	Enterococcus faecalis TX2137 Scfld36, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454136	Enterococcus faecalis TX2137 Scfld311, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454126	Enterococcus faecalis TX2137 Scfld245, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454117	Enterococcus faecalis TX2137 Scfld203, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454132	Enterococcus faecalis TX2137 Scfld280, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_GL454133	Enterococcus faecalis TX2137 Scfld282, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_GL454150_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_GL454150_1

110492-111199

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	CRT

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_GL454150_1

>merge|NZ_GL454150|1|110492-111199|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,CRT
CGTATTTGCGAAAACTAAACAACATGACTCTAAAACGTTCTACATATGTAATGAATGCTCATTAGAGATTTGGTACCATTCTAAACAACATGACTCTAAAACTTTAACAGCTGTGAAGGGCATTCTAACGAGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACACGACATGTGACAATCCATAAATTGTACCTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTGTGAAAGTAAATACCATCGGTTTTCATCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGCGCTGTTTGCTCTGTCACGTCTTTTCTAAGTTTTGGTACCATTCTAAACAACATGACTCTNNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGTGTTTTGGTACCATTCTAAACAACATGACTCTANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACACTGTGGGGCTTGCTACTTTTCCGGCGCTGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACACATGTTTCGTTATGTATGAATTTAAAACAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAGCGTGTTAGGAGGAGAAAACGAATGAGCAGTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACC

>NZ_GL454150|1|1|110492-111198|CRISPRCasFinder
CGTATTTGCGAAAACTAAACAACATGACTCTAAAAC	GTTCTACATATGTAATGAATGCTCATTAGA
GATTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTTAACAGCTGTGAAGGGCATTCTAACGAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACGACATGTGACAATCCATAAATTGTACCT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TGTGAAAGTAAATACCATCGGTTTTCATCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCGCTGTTTGCTCTGTCACGTCTTTTCTAA
GTTTTGGTACCATTCTAAACAACATGACTCTNNNNN	NNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGT
GTTTTGGTACCATTCTAAACAACATGACTCTANNNN	NNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACACTGTGGGGCTTGCTACTTTTCCGGCGCTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACATGTTTCGTTATGTATGAATTTAAAACA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGCGTGTTAGGAGGAGAAAACGAATGAGCAGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_GL454150|1|1|110494-110857|CRT
TATTTGCGAAAACTAAACAACATGACTCTAAAAC	GTTCTACATATGTAATGAATGCTCATTAGAGA
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTTAACAGCTGTGAAGGGCATTCTAACGAGGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACGACATGTGACAATCCATAAATTGTACCTGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TGTGAAAGTAAATACCATCGGTTTTCATCAGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCGCTGTTTGCTCTGTCACGTCTTTTCTAAGT
TTTGGTACCATTCTAAACAACATGACTCTNNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGTGTTTTGGTACCATTCTAAACAACATGACTCTANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACA	CTGTGGGGCTTGCTACTTTTCCGGCGCTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	CATGTTTCGTTATGTATGAATTTAAAACA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	GCGTGTTAGGAGGAGAAAACGAATGAGCAGT


>NZ_GL454150|1|1|110560-110791|PILER-CR
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTTAACAGCTGTGAAGGGCATTCTAACGAGGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACGACATGTGACAATCCATAAATTGTACCTGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TGTGAAAGTAAATACCATCGGTTTTCATCAGT
TTTGGTACCATTCTAAACAACATGACTCTAAAACGCGCTGTTTGCTCTGTCACGTCTTTTCTAAGTTTTGGTACCATTCTAAACAACATGACTCTNNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGTGTTTTGGTACCATTCTAAACAACATGACTCTANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACA	CTGTGGGGCTTGCTACTTTTCCGGCGCTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	CATGTTTCGTTATGTATGAATTTAAAACA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	GCGTGTTAGGAGGAGAAAACGAATGAGCAGT


>NZ_GL454150|1|2|110963-111199|PILER-CR
	TTTAACAGCTGTGAAGGGCATTCTAACGAGGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACGACATGTGACAATCCATAAATTGTACCTGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TGTGAAAGTAAATACCATCGGTTTTCATCAGT
TTTGGTACCATTCTAAACAACATGACTCTAAAACGCGCTGTTTGCTCTGTCACGTCTTTTCTAAGTTTTGGTACCATTCTAAACAACATGACTCTNNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGTGTTTTGGTACCATTCTAAACAACATGACTCTANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACA	CTGTGGGGCTTGCTACTTTTCCGGCGCTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	CATGTTTCGTTATGTATGAATTTAAAACA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	GCGTGTTAGGAGGAGAAAACGAATGAGCAGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACC

>NZ_GL454150|1|2|110963-111199|CRT
	GTTCTACATATGTAATGAATGCTCATTAGAGA
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTTAACAGCTGTGAAGGGCATTCTAACGAGGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACGACATGTGACAATCCATAAATTGTACCTGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	TGTGAAAGTAAATACCATCGGTTTTCATCAGT
TTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCGCTGTTTGCTCTGTCACGTCTTTTCTAAGT
TTTGGTACCATTCTAAACAACATGACTCTNNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACAACAAACCTTTTTTGGATTTGAAGGCACGTGTTTTGGTACCATTCTAAACAACATGACTCTANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACA	CTGTGGGGCTTGCTACTTTTCCGGCGCTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	CATGTTTCGTTATGTATGAATTTAAAACA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACA	GCGTGTTAGGAGGAGAAAACGAATGAGCAGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_GL454150.1\|WP_002364837.1\|120399_122049_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_GL454150.1\|WP_002367993.1\|107471_108425_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_GL454150.1\|WP_002367997.1\|103237_103792_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_GL454150.1\|WP_002401854.1\|102262_103114_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_GL454150.1\|WP_002378012.1\|111291_111951_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_GL454150.1\|WP_002355518.1\|99318_99660_-\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|237467
NZ_GL454150.1\|WP_002358655.1\|118007_119423_-\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|130941
NZ_GL454150.1\|WP_002378020.1\|99722_101909_-\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_GL454150.1\|WP_002364833.1\|111951_112281_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_GL454150.1\|WP_002401855.1\|103802_105323_-\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|215211
NZ_GL454150.1\|WP_002364834.1\|112277_113144_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_GL454150.1\|WP_002378008.1\|119556_120291_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_GL454150.1\|WP_002381241.1\|108660_109674_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_GL454150.1\|WP_002358653.1\|123845_124418_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223477
NZ_GL454150.1\|WP_002355509.1\|105356_105812_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_GL454150.1\|WP_002378016.1\|105953_107471_-\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_GL454150.1\|WP_002393823.1\|122228_123779_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	unknown	unknown	gnl\|CDD\|237588
NZ_GL454150.1\|WP_002378021.1\|97927_99163_-\|DNA-repair-exonuclease	unknown	unknown	gnl\|CDD\|277319
NZ_GL454150.1\|WP_002355504.1\|117630_117864_-\|hypothetical-protein	unknown	unknown	unknown
NZ_GL454150.1\|WP_002378009.1\|113144_117158_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044

Protein	Function_ID	Function_description	E-value
NZ_GL454150.1\|WP_002364837.1\|120399_122049_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.27874e-136
NZ_GL454150.1\|WP_002367993.1\|107471_108425_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.78143e-140
NZ_GL454150.1\|WP_002367997.1\|103237_103792_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.36986e-26
NZ_GL454150.1\|WP_002401854.1\|102262_103114_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.48238e-91
NZ_GL454150.1\|WP_002378012.1\|111291_111951_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.59659e-118
NZ_GL454150.1\|WP_002355518.1\|99318_99660_-\|YlbF-family-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	2.56028e-37
NZ_GL454150.1\|WP_002358655.1\|118007_119423_-\|dipeptidase-PepV	gnl\|CDD\|130941	TIGR01886, Beta-Ala-Xaa_dipeptidase, dipeptidase PepV. This model represents a small clade of dipeptidase enzymes which are members of the larger M25 subfamily of metalloproteases. Two characterized enzymes are included in the seed. One, from Lactococcus lactis has been shown to act on a wide range of dipeptides, but not larger peptides. The enzyme from Lactobacillus delbrueckii was originally characterized as a Xaa-His dipeptidase, specifically a carnosinase (beta-Ala-His) by complementation of an E. coli mutant. Further study, including the crystallization of the enzyme, has shown it to also be a non-specific dipeptidase. This group also includes enzymes from Streptococcus and Enterococcus. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_GL454150.1\|WP_002378020.1\|99722_101909_-\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_GL454150.1\|WP_002364833.1\|111951_112281_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.08189e-44
NZ_GL454150.1\|WP_002401855.1\|103802_105323_-\|phosphoglucomutase	gnl\|CDD\|215211	PLN02371, PLN02371, phosphoglucosamine mutase family protein.	0
NZ_GL454150.1\|WP_002364834.1\|112277_113144_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.59266e-115
NZ_GL454150.1\|WP_002378008.1\|119556_120291_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	1.63579e-91
NZ_GL454150.1\|WP_002381241.1\|108660_109674_+\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.63008e-11
NZ_GL454150.1\|WP_002358653.1\|123845_124418_-\|hypothetical-protein	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	4.15912e-18
NZ_GL454150.1\|WP_002355509.1\|105356_105812_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	1.0984e-46
NZ_GL454150.1\|WP_002378016.1\|105953_107471_-\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.15846e-168
NZ_GL454150.1\|WP_002393823.1\|122228_123779_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	gnl\|CDD\|237588	PRK14022, PRK14022, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.	0
NZ_GL454150.1\|WP_002378021.1\|97927_99163_-\|DNA-repair-exonuclease	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.16125e-50
NZ_GL454150.1\|WP_002378009.1\|113144_117158_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0

>NZ_GL454150.1|WP_002381241.1|108660_109674_+|acyltransferase-family-protein
MENDKRIYKWDNVKLFLIFLVIFGHILDREASPSRLMETINFWIYSFHMPAFIFVSGLFSKHAIKQRKYLRLLSFVWLYLLAKLLITLANFAFANKMNFDLLNETGVPWYLLSLASFYLITIFLQRVQPKIMLPIIIVIGCASGYLPVEGFLSLGRTLGFFPFFYCGYLMDIQKLQTFLDHRKVKWAAIGVILSSFLFVNSQWSLATKFWGFLTGWASYAEISPAFEYSSFIQLFFYVAAALVSLSWFALLPKRKLPLSALGKDTLYPYLLHMPLIILLESGLQLDTLFKEWFTFRILALFFLALFILAITNMPVVKRGADYLFNPQSIMIPKKIYK
>NZ_GL454150.1|WP_002367993.1|107471_108425_-|ABC-transporter-ATP-binding-protein
MIKFQNVSKVYQENAVLSDVNLTIQQGEFFVLVGPSGSGKTTTLKMINRLIEPTTGEVALNEQAVTNYPLRELRLKIGYVLQQIALFPNLTVAENIELIPEMKKWPKEQRRERTIELLKKVQLNPEEYLHRKPAALSGGEQQRIGILRAIAAEPEVILMDEPFSALDPISRHHLQRLVKELHQELASTIVFVTHDMNEALLLGERICIMDAGKIIQVDTPEAIQKHPKNNFVGQFFKQSSPELANYCGADLTAFLEAADETIEPVPTVFMETNLKEIVQLINAQEKANLVEKQQVLGCITSKTITRFMEQLLESEGQ
>NZ_GL454150.1|WP_002378016.1|105953_107471_-|ABC-transporter-permease/substrate-binding-protein
MQALIETFFARKEEYLQALIEHMQLSFISLLFAALIAIPLAIYLTSHRKLAESLLQVTGIFQTIPSLALLGLLIPLIGIGQPPAIVALVIYALFPILQNTYTGLTEIDPSLEEAAEAFGMSKKEKLFKFELQMALPFIISGIRTATVLIIGTATLAALIGAGGLGTFILLGIDRNNLSLIFIGALSSAALAVLFNYGIHWLEKANGRRLIIGGTILGLLLGGSFFWNQQTSSKEKQLTIAGKLGAEPDIIINMYKALIEENSDIQVTLKPNFGKTTFLYNALKSDEIDLYPEFTGTVIETFLKNPPQLDNQPQVVYEAARAGLKKQENLTLLKPMRYENTYAVAVKRSFAKAHQLKTISDLQKISNQLKAGFTLEFIDRQDGYKGLQEKYHLNLNVQSMEPALRYQAINNGEVNVIDAYSTDSELRQYDLVTLEDDQALFPPYQGAPLIKTATLEKYPELAEILNKLAGKISEEEMSEMNYQVNVEGQDPSIVAKDYLKEKNLLK
>NZ_GL454150.1|WP_002355509.1|105356_105812_-|arginine-repressor
MKKAERQRLIKQLIMQQEIETQDELITRLEELGVRATQATVSRDIREMSIVKTHGADGRVKYAIFSQAQGTSSEEKLRESVKDSVVRMERVQFIVILHTEMGNADVVSNFLDEVAYPEVAGTVAGADTIIVITRSEEDAEHFIERIENMIF
>NZ_GL454150.1|WP_002401855.1|103802_105323_-|phosphoglucomutase
MVELKALQNGSDIRGIALDTEEQTATLTATAVAEIAVGVVRWLQDKKQLPRKAQQRLTIAIGHDSRLTAEPIKQALVDTFLSLGIQVIDVGLATTPAMFMATQFPTLQCDAAIMITASHLPYYFNGLKFFTAEGGAEKEDIRYILSHTDPLTANENGTLMKQELLPIYAEHLVAKIRQGIHSPEEKPLQGFRIIVDAGNGAGGFFAEQVLQVLGADTTGSQFLEPDGHFPNHVPNPDNSEAMKSIQTAVLANQADLGIIFDTDVDRSAVVDQSGEVLNRNNLIAVLAAIVLKEAPGSYIVTNSPTSSHLKTFIEEKGGQQIRYISGYRNVINKMIELNHGGFQTPLAIETSGHAAFQENYNLDDGAYVVAKILMLLPELKQNNQTLGDLIATLKQPAETNEFRFKITAEDVTCYGQQVLRDFELFVESQADFAVDRENQEGVRGNVSGQYGSGWFLLRLSLHEPLLVLQVENDQSDKNACVIEKIATFLQKYEEIDSQQIENNLGN
>NZ_GL454150.1|WP_002367997.1|103237_103792_-|GNAT-family-N-acetyltransferase
MENVLKGKHIGFSHFREEYIEHIAKQQWDNELLRHLSWDALHPWGLEEWKDFTINKGEDDRFLFAILENTTEEFIGWVSLSDVQLKNRGANLGIAILQKEQRGQGYGFEAVSLICKFAFYELGLHKIRLAVNSNNQKAIHVYEKVGFKKEGIDREALFQDGQWLDIYNYGILQKEWLQMIKAES
>NZ_GL454150.1|WP_002401854.1|102262_103114_+|RluA-family-pseudouridine-synthase
MRLPENFSTMTVKELLENEWLVPRKVRHFLRTRKNVKINGETAAFHFPVQAGDCVTLTFEETDYVRPTIHLGEATHVKVLYEDEHLMIVNKPYGIKTHPNQPQETDTLLNHVAAYLAEKNQVPYVVHRLDKETSGAIVFAKNPFVLPILGRLLETKQIYRQYQAIVAGHFNQKEQTINQPIGRDRHDRRKRRIDPQKGDSAITHVQVVQALSNNQTAVTCVLETGRTHQIRVHLASEGHPIIGDPLYNPKSQAARLMLHASQLHLLHPFTKKQIVVTAAPGLW
>NZ_GL454150.1|WP_002378020.1|99722_101909_-|PBP1A-family-penicillin-binding-protein
MDNLKQFFSKVGVGLRHFWTWIKPYLIQFHQARKRIWKKYQINKIFLLIGLVVALGASIYLFYLAKSANVETLKSGLSESTRVYDESGEEVGKLFGQKGTFVELDNISPYIQDAVISTEDRGFYQHKGYSIKGIARAVVGKLTFGKIGGGGGGSTITQQLAKNAYLTQEQTLDRKARELFLAIEIEKKYSKKDILAMYLNNSYFGNGVWGVQDAARKYFGVDASQVTVGEAATLAGMLKGPGIYNPIDYIDNATARRNTVLQLMVDNKKLSQEEANQEASVNLASLLNDTYVGDENSYKYPYYFDAVIDEAVNRYKFKEEDILNKGYKIYTSLNQGYQDAMDATYKNDALFPPNAEDGAMVQSGSVAIDPKTGGVQALVGGRGEHVYRGFNFATQTKRSPGSSLKPISVYTPALEAGYKPDSVLEDKPQDYYPAQNYSRTYSGEVPMYQALGESLNLPAVWLLHQIGLDKGYEKTEKFGIPLSEKDRYYGLALGGLQTGVSPLTMAGAYSAFANEGYKTETHLITKIVDSTGAIVVDNTKVKKEQVITKDVADGITSMLLGVFSSGSGVNAQPAGYVMAGKTGTTETNFDSSKTNDQWVIGYTPEVVIATWLGFQETSKTHYLEGSSATYASQVFNSQASGILPQVKQAQFPVADAYATGGKVVDSNDSLTGGANSNWRDNLKDFGNSVQDGASNFGDTLNEVGGQIKDGAKKVKDKIEGIFGGLLGN
>NZ_GL454150.1|WP_002355518.1|99318_99660_-|YlbF-family-regulator
MSNIYDTANQIERELRELDEFKALQAAYEEVKADEAAYTLFKEFQGFQQGLQEKQMRGEEFTDEDAEKAQSIATKVQETAVINELMQKEQAFSLVVNDLNRIIMTPVRDMYND
>NZ_GL454150.1|WP_002378021.1|97927_99163_-|DNA-repair-exonuclease
MKLLHTADLHMDRSFEGLTGIPTALAKRLREANQQLLMNIVTVAIREAVDLVIFAGDTFHQSQTSISMQAQLMAALEQLKQAEIPVILTFGNHDYYKKDRYWFSFPDNVFLFEKEMVETLYFETRAGEQVAVSGFSYEHPWIDENKALEFPIKQADSDIHIGIYHGDTSRKAQQNYAPFTWKDLKATGYNYWALGHIHQPQIVSEQPLIVYPGTPQGHTKKEQSLQGVAVVTLSQNQATVQFEKVAEIDWTNEEVSLAQCRDTQSVLSYLETSLLTKWHAHQQQQLMALTLKETQHLDVTVVQAIVNGELLSYLQQQLLQKTQGDFFVYRLILQAEEPTKEPIYLSASPNLLTALEKTYLDPVIFEDTTKELLRYPEFAGIFSMDEQWRSESLRLAHEQINEDFTIQEDPL
>NZ_GL454150.1|WP_002378012.1|111291_111951_-|type-II-A-CRISPR-associated-protein-Csn2
MRVNFSLLEEPIEIEKATFLTIKDVQTFAHLVKLIYQYDGENDLKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGITVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA
>NZ_GL454150.1|WP_002364833.1|111951_112281_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRLLLMFDMPTDTASDRKAYRKFRKFLINEGFIMHQFSVYSKILLNDTANKAMLARLKQNNPQRGLITLLNVTEKQFSRMIYLHGEQDNRVANSDERIVFLGEE
>NZ_GL454150.1|WP_002364834.1|112277_113144_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNKHSKLSYKNNHLVFKAIDHQELIHLSEIDVLLLETTDISLTTMLLKRLIDEKILVLFCDDKRLPIGKILPFYGRHDSSLQLTRQLAWTEERKGQVWTAIIAQKITNQSLHLAQRDYGQKAAALLAMRAELRLFDPANREGHAARSYFNTLFGNDFTREQENDINAGLNYGYTLLLSIFARELVQTGCFTQLGLKHANQFNDFNLASDLMEPFRPLVDQIIYENRKEAFPIMKRKLFALFMNTYMYKKKQMFLTNIATDYTKHVVKVLNQEEEGVPEFGI
>NZ_GL454150.1|WP_002378009.1|113144_117158_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKDYVIGLDIGTNSVGWAVMTEDYQLVKKKMPIYGNTEKKKIKKNFWGVRLFEEGHTAEDRRLKRTARRRISRRRNRLRYLQAFFEEAMTALDENFFARLQESFLVPEDKKWHRHPIFAKLEDEVAYHETYPTIYHLRKKLADSSEQADLRLIYLALAHIVKYRGHFLIEGKLSTENISVKEQFQQFMIIYNQTFVNGESRLVSAPLPESVLIEEELTEKASRTKKSEKVLQQFPQEKANGLFGQFLKLMVGNKADFKKVFGLEEEAKITYASESYEEDLEGILAKVGDEYSDVFLAAKNVYDAVELSTILADSDKKSHAKLSSSMIVRFTEHQEDLKNFKRFIRENCPDEYDNLFKNEQKDGYAGYITHAGKVSQLKFYQYVKKIIQDIAGAEYFLEKIAQENFLRKQRTFDNGVIPHQIHLAELQAIIHRQAAYYPFLKENQEKIEQLVTFRIPYYVGPLSKGDANTFAWLKRQSEEPIRPWNLQETVDLDQSATAFIERMTNFDTYLPSEKVLPKHSLLYEKFMVFNELTKISYTDDRGIKANFSGKEKEKIFDYLFKTRRKVKKKDIIQFYRNEYNTEIVTLSGLEEDQFNASFSTYQDLLKCGLTRAELDHPDNAEKLEDIIKILTIFEDRQRIRTQLSTFKGQFSAEVLKKLERKHYTGWGRLSKKLINGIYDKESGKTILDYLIKDDGVSKHYNRNFMQLINDSQLSFKNAIQKAQSSEHEETLSETVNELAGSPAIKKGIYQSLKIVDELVAIMGYAPKRIVVEMARENQTTSTGKRRSIQRLKIVEKAMAEIGSNLLKEQPTTNEQLRDTRLFLYYMQNGKDMYTGDELSLHRLSHYDIDHIIPQSFMKDDSLDNLVLVGSTENRGKSDDVPSKEVVKDMKAYWEKLYAAGLISQRKFQRLTKGEQGGLTLEDKAHFIQRQLVETRQITKNVAGILDQRYNAKSKEKKVQIITLKASLTSQFRSIFGLYKVREVNDYHHGQDAYLNCVVATTLLKVYPNLAPEFVYGEYPKFQTFKENKATAKAIIYTNLLRFFTEDEPRFTKDGEILWSNSYLKTIKKELNYHQMNIVKKVEVQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVLFTHEKGKKPLIKQEILGITIMEKTRFEQNPILFLEEKGFLRPRVLMKLPKYTLYQFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKQCLLPNQSESLAYVEQHQPEFQEILERVVDFAEVHTLAKSKVQQIVKLFEANQTADVKEIAASFIQLMQFNAMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVVD
>NZ_GL454150.1|WP_002355504.1|117630_117864_-|hypothetical-protein
MSETLIVNYLIKGRVKMNVEELVQKAKDLIGEGNVEHAQQFIEEHKDELGEHYHKITAMLADTTTDGLFDKIKGLFQ
>NZ_GL454150.1|WP_002358655.1|118007_119423_-|dipeptidase-PepV
MTIDWTKEVEARKDDLLEDLQNLLRINSERDDAQATPEAPFGPGPVAGLKHMLAYGERDGFTVKNVDNYAGHIEYGEGDETLGIFGHMDVVPAGDGWETDPYEPVIKDGKIYARGASDDKGPSMAAYYAMKIIKELGLPVSKKIRFVVGSDEESGWGDMDYYFQHEEAPDFGFSPDAEFPIINGEKGNVTIRLTFRGGNGADYKLESFKSGLRENMVPGTADAVVTAASADEAASLAASFETFIKQEAKISGNAELSDKTVTFHVVGKGAHGASPQSGINAATFLATFLNDYSFAEGAYSFINTIAEFIHEDFYGEKLGVAFEDEKMGKLTMNAGIVNFDPENPENSLVTLNFRYPKGTSAEELQAKVQATVGETVTATQGDRNQEPHYVPVDDPLVATLLQVYEDHTGEKGQEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEFMELDDLFRAAAIYADAIYRLAK
>NZ_GL454150.1|WP_002378008.1|119556_120291_-|rRNA-pseudouridine-synthase
MRLDKFLADVGIGSRKEIKQLLKKKVVTVNGDVVKEAKTQVNEETDQIALMGEILTYQKFFYYMLHKPQGVISATEDQRDETVIDLLTDQDYRADLFPVGRLDKDTEGLLLLTNDGQLAHQLLSPKKHVDKEYLAEVEGLVTAEDCQLFAQGFALKDGEMVKPSRLVIETINEEEGTSVVRLVIQEGKFHQVKRMLATVGKPVTYLKRLRMGELWLDETLELGGYRPLTEAELQQLQPKQSYLN
>NZ_GL454150.1|WP_002364837.1|120399_122049_-|polysaccharide-biosynthesis-protein
MINQPNSVDQPILTNQEKMVKGSAWMTASNIISRMLGAIYIIPWYAWMGEHGNEANSLFSMGYTIYALFLMISTAGIPGAIAKQTSHYNSLNEYKISRQLFYRALQLMGGLGVVFAIVMYLASPALAALSGGGPELVPTMRSLSLAVLVFPSMSVIRGYFQGNQEMMPFALSQIVEQVARVFYMLLTAFIIMKVFEGNYVTAVTQATFAAFIGMLASFAVLGYYMYKQKPLFDYLEEHSANEHEIAPKELLIETFKEAIPFIVVGSGVTVFKLVDQFTFSNFMRLFTDYSDTQLRELFGIFNANPDKLTMIVVALATSISATGLPLITEAVTLKNHRELARLISNNLQLFVFVMLPATFGMIVLAQPLYTVFYMPDALGTSLLVQACYASLFLGLYMLVSNMLMGMYENRDAMRYLGIGLAVKLIVQFPAIRLFEVYGPLLATMIGFTVSCVLILRRIRQVTRFNYKLTLRRTLLMFCITVIMMIIALIFRQFLYLFLDPTRRFQAFIIVVIVAAAGGAFYGYSVLKIRLADRLLGKNAAKLRAKFNIK
>NZ_GL454150.1|WP_002393823.1|122228_123779_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase
MKRLEAKKVTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTILDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAEAFINKKN
>NZ_GL454150.1|WP_002358653.1|123845_124418_-|hypothetical-protein
MKQFFQKGSKPNQLVVAFHGTGGNEYQLLTTIATLYPEASVLSYLGTEGVGEQRRFFAPLVNGALPRANFDERVTAFLEEVWQPQKLYDEVIFIGYSNGANFILGLLEKNPTIANTVILLHPSNLGYQYVSGEFATKVIVTTGAQDELSIPGQVLSLANQLKKHFPVDFLLVDGGHGLSEEEVTKIKEVL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_GL454150_1	1.4\|110726\|30\|NZ_GL454150\|CRISPRCasFinder	110726-110755	30	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	40757-40786	6	0.8
NZ_GL454150_1	1.8\|111065\|30\|NZ_GL454150\|CRISPRCasFinder	111065-111094	30	NZ_CP014570	Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence	14813-14842	6	0.8
NZ_GL454150_1	1.8\|111065\|30\|NZ_GL454150\|CRISPRCasFinder	111065-111094	30	NZ_CP043436	Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence	10209-10238	6	0.8
NZ_GL454150_1	1.8\|111065\|30\|NZ_GL454150\|CRISPRCasFinder	111065-111094	30	NZ_CP008809	Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence	2921-2950	6	0.8
NZ_GL454150_1	1.8\|111065\|30\|NZ_GL454150\|CRISPRCasFinder	111065-111094	30	NZ_CP008812	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence	10382-10411	6	0.8
NZ_GL454150_1	1.16\|111066\|29\|NZ_GL454150\|PILER-CR,CRT	111066-111094	29	NZ_CP014570	Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence	14814-14842	6	0.793
NZ_GL454150_1	1.16\|111066\|29\|NZ_GL454150\|PILER-CR,CRT	111066-111094	29	NZ_CP043436	Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence	10209-10237	6	0.793
NZ_GL454150_1	1.16\|111066\|29\|NZ_GL454150\|PILER-CR,CRT	111066-111094	29	NZ_CP008809	Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence	2922-2950	6	0.793
NZ_GL454150_1	1.16\|111066\|29\|NZ_GL454150\|PILER-CR,CRT	111066-111094	29	NZ_CP008812	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence	10383-10411	6	0.793
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	9754-9783	7	0.767
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	20272-20301	7	0.767
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP031904	Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence	60569-60598	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_011752	Escherichia coli 55989 plasmid 55989p, complete sequence	49973-50002	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	CP042952	Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence	67474-67503	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP026724	Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence	101148-101177	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	CP051693	Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence	31503-31532	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_019000	Escherichia coli plasmid pHUSEC41-2, complete sequence	51056-51085	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP009053	Escherichia coli NCCP15648 plasmid p15648-3, complete sequence	55603-55632	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	10746-10775	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_018662	Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence	58558-58587	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_018654	Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence	17881-17910	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP023530	Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence	6482-6511	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP041001	Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence	63459-63488	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	CP025574	Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence	51314-51343	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP013186	Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence	39899-39928	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP023533	Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence	24355-24384	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP022087	Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence	40046-40075	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	CP049615	Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence	17811-17840	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NC_022743	Escherichia coli plasmid pHUSEC2011-2, complete sequence	53979-54008	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP027392	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence	4511-4540	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP023062	Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence	55180-55209	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_CP023552	Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence	47364-47393	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	NZ_KY706108	Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence	60040-60069	8	0.733
NZ_GL454150_1	1.1\|110528\|30\|NZ_GL454150\|CRISPRCasFinder	110528-110557	30	KU886273	Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome	26680-26709	8	0.733
NZ_GL454150_1	1.5\|110792\|30\|NZ_GL454150\|CRISPRCasFinder	110792-110821	30	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	710636-710665	8	0.733
NZ_GL454150_1	1.5\|110792\|30\|NZ_GL454150\|CRISPRCasFinder	110792-110821	30	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	219326-219355	8	0.733
NZ_GL454150_1	1.5\|110792\|30\|NZ_GL454150\|CRISPRCasFinder	110792-110821	30	NZ_CP053224	Sphingobium sp. RSMS plasmid pRSMS1, complete sequence	48396-48425	8	0.733
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	9752-9783	9	0.719
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP031270	Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence	20272-20303	9	0.719
NZ_GL454150_1	1.17\|111132\|31\|NZ_GL454150\|PILER-CR,CRT	111132-111162	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1915425-1915455	9	0.71
NZ_GL454150_1	1.9\|111131\|32\|NZ_GL454150\|CRISPRCasFinder	111131-111162	32	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1915425-1915456	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP031904	Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence	60567-60598	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_011752	Escherichia coli 55989 plasmid 55989p, complete sequence	49973-50004	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	CP042952	Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence	67474-67505	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP026724	Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence	101148-101179	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	CP051693	Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence	31503-31534	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_019000	Escherichia coli plasmid pHUSEC41-2, complete sequence	51056-51087	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP009053	Escherichia coli NCCP15648 plasmid p15648-3, complete sequence	55603-55634	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	10746-10777	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_018662	Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence	58558-58589	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_018654	Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence	17879-17910	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP023530	Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence	6480-6511	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP041001	Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence	63457-63488	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	CP025574	Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence	51312-51343	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP013186	Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence	39899-39930	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP023533	Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence	24353-24384	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP022087	Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence	40046-40077	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	CP049615	Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence	17811-17842	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NC_022743	Escherichia coli plasmid pHUSEC2011-2, complete sequence	53979-54010	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP027392	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence	4509-4540	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP023062	Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence	55178-55209	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_CP023552	Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence	47362-47393	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	NZ_KY706108	Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence	60038-60069	10	0.688
NZ_GL454150_1	1.10\|110528\|32\|NZ_GL454150\|CRT	110528-110559	32	KU886273	Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome	26680-26711	10	0.688

1. spacer 1.4|110726|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 6, identity: 0.8

tgtgaaagtaaataccatcggttttcatca	CRISPR spacer
ttcgaaagaaaataccatcggtttttacct	Protospacer
* .***** ****************.*.*

2. spacer 1.8|111065|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP014570 (Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence) position: , mismatch: 6, identity: 0.8

-acatgtttcgttatgtatgaatttaaaaca	CRISPR spacer
aatataaat-gttatggatgaatttaaaaca	Protospacer
 *.**.  * ****** **************

3. spacer 1.8|111065|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP043436 (Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence) position: , mismatch: 6, identity: 0.8

-acatgtttcgttatgtatgaatttaaaaca	CRISPR spacer
aatataaat-gttatggatgaatttaaaaca	Protospacer
 *.**.  * ****** **************

4. spacer 1.8|111065|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP008809 (Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence) position: , mismatch: 6, identity: 0.8

-acatgtttcgttatgtatgaatttaaaaca	CRISPR spacer
aatataaat-gttatggatgaatttaaaaca	Protospacer
 *.**.  * ****** **************

5. spacer 1.8|111065|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP008812 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence) position: , mismatch: 6, identity: 0.8

-acatgtttcgttatgtatgaatttaaaaca	CRISPR spacer
aatataaat-gttatggatgaatttaaaaca	Protospacer
 *.**.  * ****** **************

6. spacer 1.16|111066|29|NZ_GL454150|PILER-CR,CRT matches to NZ_CP014570 (Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence) position: , mismatch: 6, identity: 0.793

catgt-ttcgttatgtatgaatttaaaaca	CRISPR spacer
-atataaatgttatggatgaatttaaaaca	Protospacer
 **.*   .****** **************

7. spacer 1.16|111066|29|NZ_GL454150|PILER-CR,CRT matches to NZ_CP043436 (Campylobacter fetus subsp. venerealis NCTC 10354 plasmid p3226, complete sequence) position: , mismatch: 6, identity: 0.793

catgt-ttcgttatgtatgaatttaaaaca	CRISPR spacer
-atataaatgttatggatgaatttaaaaca	Protospacer
 **.*   .****** **************

8. spacer 1.16|111066|29|NZ_GL454150|PILER-CR,CRT matches to NZ_CP008809 (Campylobacter fetus subsp. fetus 04/554 plasmid pCFF04554, complete sequence) position: , mismatch: 6, identity: 0.793

catgt-ttcgttatgtatgaatttaaaaca	CRISPR spacer
-atataaatgttatggatgaatttaaaaca	Protospacer
 **.*   .****** **************

9. spacer 1.16|111066|29|NZ_GL454150|PILER-CR,CRT matches to NZ_CP008812 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-2, complete sequence) position: , mismatch: 6, identity: 0.793

catgt-ttcgttatgtatgaatttaaaaca	CRISPR spacer
-atataaatgttatggatgaatttaaaaca	Protospacer
 **.*   .****** **************

10. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
aatgtatataagtaatgaatgctcatttaa	Protospacer
. * **.*** **************** .*

11. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
aatgtatataagtaatgaatgctcatttaa	Protospacer
. * **.*** **************** .*

12. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP031904 (Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

13. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_011752 (Escherichia coli 55989 plasmid 55989p, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

14. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to CP042952 (Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

15. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP026724 (Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

16. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to CP051693 (Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

17. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_019000 (Escherichia coli plasmid pHUSEC41-2, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

18. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP009053 (Escherichia coli NCCP15648 plasmid p15648-3, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

19. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_018666 (Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

20. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_018662 (Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

21. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_018654 (Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

22. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP023530 (Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

23. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP041001 (Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

24. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to CP025574 (Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

25. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP013186 (Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

26. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP023533 (Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

27. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP022087 (Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

28. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to CP049615 (Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

29. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NC_022743 (Escherichia coli plasmid pHUSEC2011-2, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

30. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP027392 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

31. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP023062 (Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

32. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP023552 (Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

33. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to NZ_KY706108 (Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttg	Protospacer
   .******************* ***  .

34. spacer 1.1|110528|30|NZ_GL454150|CRISPRCasFinder matches to KU886273 (Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome) position: , mismatch: 8, identity: 0.733

gttctacatatgtaatgaatgctcattaga	CRISPR spacer
gttctacatttgtaatgaatactagcccaa	Protospacer
********* **********.** ... .*

35. spacer 1.5|110792|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctgtttgctctgtcacgtc---ttttctaa	CRISPR spacer
tcgctgtttcctctgtcacgtcagacgctc---	Protospacer
 ******** ************   . .**

36. spacer 1.5|110792|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctgtttgctctgtcacgtc---ttttctaa	CRISPR spacer
tcgctgtttcctctgtcacgtcagacgctc---	Protospacer
 ******** ************   . .**

37. spacer 1.5|110792|30|NZ_GL454150|CRISPRCasFinder matches to NZ_CP053224 (Sphingobium sp. RSMS plasmid pRSMS1, complete sequence) position: , mismatch: 8, identity: 0.733

gcgctgtttgctctgtcacgtc---ttttctaa	CRISPR spacer
tcgctgtttcctctgtcacgtcagacgctc---	Protospacer
 ******** ************   . .**

38. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
aatgtatataagtaatgaatgctcatttaact	Protospacer
. * **.*** **************** .*

39. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP031270 (Staphylococcus warneri strain 16A plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
aatgtatataagtaatgaatgctcatttaact	Protospacer
. * **.*** **************** .*

40. spacer 1.17|111132|31|NZ_GL454150|PILER-CR,CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 9, identity: 0.71

gcgtgttaggaggagaaaacgaatgagcagt	CRISPR spacer
caattcgcggagggggaaacgaatgagcagt	Protospacer
  .* .  *****.*.***************

41. spacer 1.9|111131|32|NZ_GL454150|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 10, identity: 0.688

agcgtgttaggaggagaaaacgaatgagcagt	CRISPR spacer
gcaattcgcggagggggaaacgaatgagcagt	Protospacer
.  .* .  *****.*.***************

42. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP031904 (Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

43. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_011752 (Escherichia coli 55989 plasmid 55989p, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

44. spacer 1.10|110528|32|NZ_GL454150|CRT matches to CP042952 (Escherichia coli strain D8-1 plasmid pD8-1_1, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

45. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP026724 (Escherichia coli strain 266917_2 plasmid p266917_2_01, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

46. spacer 1.10|110528|32|NZ_GL454150|CRT matches to CP051693 (Escherichia coli strain SCU-318 plasmid pSCU-318-1, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

47. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_019000 (Escherichia coli plasmid pHUSEC41-2, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

48. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP009053 (Escherichia coli NCCP15648 plasmid p15648-3, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

49. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_018666 (Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

50. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_018662 (Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

51. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_018654 (Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

52. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP023530 (Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

53. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP041001 (Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

54. spacer 1.10|110528|32|NZ_GL454150|CRT matches to CP025574 (Escherichia coli strain E-1246 plasmid pE1246_1, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

55. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP013186 (Escherichia coli strain FORC_029 plasmid FORC_029p, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

56. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP023533 (Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

57. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP022087 (Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

58. spacer 1.10|110528|32|NZ_GL454150|CRT matches to CP049615 (Escherichia coli O157:H7 strain K1516 plasmid pK1516-3, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

59. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NC_022743 (Escherichia coli plasmid pHUSEC2011-2, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

60. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP027392 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

61. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP023062 (Escherichia coli strain FORC_069 plasmid pFORC69, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

62. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_CP023552 (Escherichia coli strain FORC_043 plasmid pFORC43, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

63. spacer 1.10|110528|32|NZ_GL454150|CRT matches to NZ_KY706108 (Escherichia coli strain pAA-ST131 plasmid ESBL20150001, complete sequence) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
tagttacatatgtaatgaatgctgattttgat	Protospacer
   .******************* ***  ..

64. spacer 1.10|110528|32|NZ_GL454150|CRT matches to KU886273 (Freshwater phage uvFW-CGR-AMD-COM-C455, complete genome) position: , mismatch: 10, identity: 0.688

gttctacatatgtaatgaatgctcattagaga	CRISPR spacer
gttctacatttgtaatgaatactagcccaacc	Protospacer
********* **********.** ... .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15356 : 26270

Streptococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002356366.1\|15356_15995_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8
WP_002356367.1\|16014_16344_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_002384059.1\|16345_17296_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356371.1\|17412_18252_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002356372.1\|18244_18592_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_002359438.1\|18704_19577_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
WP_002378641.1\|19591_20254_+	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	6.9e-16	29.9
WP_002356377.1\|20237_20996_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002362328.1\|21121_22240_+	DNA polymerase IV	D0R0A3	Streptococcus_phage	4.2e-13	29.1
WP_002356379.1\|22284_22881_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002382497.1\|22913_25097_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.0e-286	66.8
WP_002356382.1\|25502_26270_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.4e-30	35.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_GL454139

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_GL454139_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_GL454139_1

138600-139304

Orphan

II-A,II-B

Consensus_repeat	Method
TAAGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAA	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT

9 spacers

The CRISPR arrays of NZ_GL454139_1

>merge|NZ_GL454139|1|138600-139304|PILER-CR,CRISPRCasFinder,CRT,PILER-CR,CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTGTTTTTAATATTGCCGTCTTTTAAATAAGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTCTTAGAACGCTATTCGGAACGCTTTAAGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTACTTTCTTGATAGATTCTTTAGCCTTATGTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACGCATCAATCAAAATTCCCTCAATCACATAAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGATAAGTATTACACATCAAAAAAATGCTTAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGGTCTTTTTTTCTTGTTCTAAATTTTGGAAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAAGCAAGAATAGTAAGAACTACAAAAATGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTGATTGGAGCTCCAACATGGGACGGTCGAGTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACGAAGATGGTAGCGAAGTTATTGTAAATCCCGTTTTGGTACCATTCTAAACAACATGACTCTAA

>NZ_GL454139|1|1|138600-138768|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTGTTT	TTAATATTGCCGTCTTTTAAATAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTCTT	AGAACGCTATTCGGAACGCTTTAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTACTTTCTTGATAGATTCTTTAGCCTTATGTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATCAATCAAAATTCCCTCAATCACATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAAGTATTACACATCAAAAAAATGCTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGTCTTTTTTTCTTGTTCTAAATTTTGGAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCAAGAATAGTAAGAACTACAAAAATGC


>NZ_GL454139|1|1|138600-139304|CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACTGTTTTTAATATTGCCGTCTTTTAAATAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACTTCTTAGAACGCTATTCGGAACGCTTTAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACTTACTTTCTTGATAGATTCTTTAGCCTTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAA	NNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACGCATCAATCAAAATTCCCTCAATCACATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACGATAAGTATTACACATCAAAAAAATGCTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACGGTCTTTTTTTCTTGTTCTAAATTTTGGAA
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACAAGCAAGAATAGTAAGAACTACAAAAATGC
GTTTTGGTACCATTCTAAACAACATGACTCTAA	AACTTGATTGGAGCTCCAACATGGGACGGTCGA
GTTTTGGTACCATTCTAAACAACATGACTCTAA	NNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAACGAAGATGGTAGCGAAGTTATTGTAAATCCC
GTTTTGGTACCATTCTAAACAACATGACTCTAA

>NZ_GL454139|1|1|138600-138834|CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	GTTTTTAATATTGCCGTCTTTTAAATAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	TCTTAGAACGCTATTCGGAACGCTTTAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	TACTTTCTTGATAGATTCTTTAGCCTTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATCAATCAAAATTCCCTCAATCACATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAAGTATTACACATCAAAAAAATGCTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGTCTTTTTTTCTTGTTCTAAATTTTGGAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCAAGAATAGTAAGAACTACAAAAATGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTGATTGGAGCTCCAACATGGGACGGTCGA


>NZ_GL454139|1|2|138837-139136|PILER-CR
	TTAATATTGCCGTCTTTTAAATAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTCTT	AGAACGCTATTCGGAACGCTTTAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACTTACTTTCTTGATAGATTCTTTAGCCTTATGTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATCAATCAAAATTCCCTCAATCACATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAAGTATTACACATCAAAAAAATGCTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGTCTTTTTTTCTTGTTCTAAATTTTGGAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCAAGAATAGTAAGAACTACAAAAATGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_GL454139|1|2|138837-139202|CRT
	GTTTTTAATATTGCCGTCTTTTAAATAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	TCTTAGAACGCTATTCGGAACGCTTTAAG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAACT	TACTTTCTTGATAGATTCTTTAGCCTTAT
GTTTTGGTACCATTCTAAACAACATGACTCTAANNNNNNNNNNTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATCAATCAAAATTCCCTCAATCACATAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAAGTATTACACATCAAAAAAATGCTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGTCTTTTTTTCTTGTTCTAAATTTTGGAA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCAAGAATAGTAAGAACTACAAAAATGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TTGATTGGAGCTCCAACATGGGACGGTCGA
GTTTTGGTACCATTCTAAACAACATGACTCTAANNN

Protein	Signature genes	Signature genes Name	Protein_function
NZ_GL454139.1\|WP_002378481.1\|139464_140328_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214874
NZ_GL454139.1\|WP_002364246.1\|132197_133964_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_GL454139.1\|WP_002356959.1\|147089_147434_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_GL454139.1\|WP_002362076.1\|148803_149778_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_GL454139.1\|WP_002362075.1\|145739_146864_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_GL454139.1\|WP_002356962.1\|144321_145560_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_GL454139.1\|WP_002378475.1\|128870_130082_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_GL454139.1\|WP_002364244.1\|125301_126003_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_GL454139.1\|WP_002378477.1\|133960_135694_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_GL454139.1\|WP_002381711.1\|124434_125184_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_GL454139.1\|WP_002401813.1\|140412_142662_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_GL454139.1\|WP_002356974.1\|136708_138127_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_GL454139.1\|WP_002401815.1\|147501_148647_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_GL454139.1\|WP_002378474.1\|126133_128557_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_GL454139.1\|WP_002356965.1\|143087_143657_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_GL454139.1\|WP_002356966.1\|142624_142990_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_GL454139.1\|WP_002356963.1\|143789_144305_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_GL454139.1\|WP_002360016.1\|130110_131016_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_GL454139.1\|WP_002356976.1\|135698_136712_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_GL454139.1\|WP_002378476.1\|131137_132118_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220

Protein	Function_ID	Function_description	E-value
NZ_GL454139.1\|WP_002378481.1\|139464_140328_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|214874	smart00871, AraC_E_bind, Bacterial transcription activator, effector binding domain. This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.	5.42864e-27
NZ_GL454139.1\|WP_002364246.1\|132197_133964_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_GL454139.1\|WP_002356959.1\|147089_147434_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_GL454139.1\|WP_002362076.1\|148803_149778_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_GL454139.1\|WP_002362075.1\|145739_146864_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_GL454139.1\|WP_002356962.1\|144321_145560_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.18762e-174
NZ_GL454139.1\|WP_002378475.1\|128870_130082_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	4.85138e-122
NZ_GL454139.1\|WP_002364244.1\|125301_126003_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.52313e-37
NZ_GL454139.1\|WP_002378477.1\|133960_135694_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_GL454139.1\|WP_002381711.1\|124434_125184_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63593e-110
NZ_GL454139.1\|WP_002401813.1\|140412_142662_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_GL454139.1\|WP_002356974.1\|136708_138127_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_GL454139.1\|WP_002401815.1\|147501_148647_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	2.81317e-177
NZ_GL454139.1\|WP_002378474.1\|126133_128557_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.30065e-174
NZ_GL454139.1\|WP_002356965.1\|143087_143657_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.91104e-15
NZ_GL454139.1\|WP_002356966.1\|142624_142990_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_GL454139.1\|WP_002356963.1\|143789_144305_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	5.73504e-32
NZ_GL454139.1\|WP_002360016.1\|130110_131016_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_GL454139.1\|WP_002356976.1\|135698_136712_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NZ_GL454139.1\|WP_002378476.1\|131137_132118_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	4.36842e-80

>NZ_GL454139.1|WP_002356974.1|136708_138127_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_GL454139.1|WP_002356976.1|135698_136712_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_GL454139.1|WP_002378477.1|133960_135694_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGITLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_GL454139.1|WP_002364246.1|132197_133964_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVAQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_GL454139.1|WP_002378476.1|131137_132118_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFGPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_GL454139.1|WP_002360016.1|130110_131016_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_GL454139.1|WP_002378475.1|128870_130082_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVQTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_GL454139.1|WP_002378474.1|126133_128557_-|DNA-translocase-FtsK
MAQKRATNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKETKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NZ_GL454139.1|WP_002364244.1|125301_126003_-|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEELFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_GL454139.1|WP_002381711.1|124434_125184_-|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIVQNGNQKEFYDLIMVKLAEIEGVDNEF
>NZ_GL454139.1|WP_002378481.1|139464_140328_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFFAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWSGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQKENQAIMELAQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFATLQENIYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_GL454139.1|WP_002401813.1|140412_142662_-|DNA-topoisomerase-III
MAKQNSANGKLFETHEFKEKPQGIFFKLFFYSRNLEKIEPIFGIIRKDSTQKGAKLVVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKEIFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_GL454139.1|WP_002356966.1|142624_142990_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_GL454139.1|WP_002356965.1|143087_143657_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAG
>NZ_GL454139.1|WP_002356963.1|143789_144305_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQLLAKAKFEFLY
>NZ_GL454139.1|WP_002356962.1|144321_145560_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDD
>NZ_GL454139.1|WP_002362075.1|145739_146864_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_GL454139.1|WP_002356959.1|147089_147434_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_GL454139.1|WP_002401815.1|147501_148647_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQMIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKNNGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_GL454139.1|WP_002362076.1|148803_149778_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE

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Crispr_ID: NZ_GL454139_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_GL454139_2

158813-158923

Orphan

Consensus_repeat	Method
TTCGTGTAAATGACACAACTTGCCCTTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_GL454139_2

>merge|NZ_GL454139|2|158813-158923|CRISPRCasFinder
TTCGTGTAAATGACACAACTTGCCCTTCGGTCATCTTGTACTGTTCATCATCTACTCTGTCGCTTCGCGCCAGTCGTAGTGATTCGTGCAAATGACACAACTTGCCCTTCG

>NZ_GL454139|2|2|158813-158923|CRISPRCasFinder
TTCGTGTAAATGACACAACTTGCCCTTCG	GTCATCTTGTACTGTTCATCATCTACTCTGTCGCTTCGCGCCAGTCGTAGTGA
TTCGTGCAAATGACACAACTTGCCCTTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_GL454139.1\|WP_002356940.1\|164789_166598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_GL454139.1\|WP_002356936.1\|170458_171814_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_GL454139.1\|WP_002378492.1\|161761_162727_-\|hypothetical-protein	unknown	unknown	unknown
NZ_GL454139.1\|WP_002366917.1\|155689_156523_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_GL454139.1\|WP_002356937.1\|169677_170229_-\|ECF-type-riboflavin-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|184218
NZ_GL454139.1\|WP_002401818.1\|161494_161674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_GL454139.1\|WP_002356956.1\|149990_150740_+\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NZ_GL454139.1\|WP_002359933.1\|167040_167874_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_GL454139.1\|WP_002356942.1\|162902_163193_-\|hypothetical-protein	unknown	unknown	unknown
NZ_GL454139.1\|WP_002364373.1\|150736_151606_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NZ_GL454139.1\|WP_002401815.1\|147501_148647_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_GL454139.1\|WP_002362076.1\|148803_149778_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_GL454139.1\|WP_002362078.1\|152573_154112_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_GL454139.1\|WP_002378495.1\|167870_169577_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_GL454139.1\|WP_002401817.1\|159790_161281_+\|glucosyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|372986
NZ_GL454139.1\|WP_002360002.1\|151592_152519_+\|metal-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238557
NZ_GL454139.1\|WP_002359998.1\|156542_157223_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_GL454139.1\|WP_002391464.1\|163240_164521_-\|aminoacyltransferase	unknown	unknown	gnl\|CDD\|367067
NZ_GL454139.1\|WP_002378488.1\|157241_158312_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236863
NZ_GL454139.1\|WP_002378487.1\|154481_155675_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349940

Protein	Function_ID	Function_description	E-value
NZ_GL454139.1\|WP_002356940.1\|164789_166598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_GL454139.1\|WP_002356936.1\|170458_171814_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_GL454139.1\|WP_002359933.1\|167040_167874_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.22427e-41
NZ_GL454139.1\|WP_002366917.1\|155689_156523_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.7228e-107
NZ_GL454139.1\|WP_002356937.1\|169677_170229_-\|ECF-type-riboflavin-transporter-substrate-binding-protein	gnl\|CDD\|184218	PRK13661, PRK13661, ECF-type riboflavin transporter substrate-binding protein.	3.25341e-93
NZ_GL454139.1\|WP_002356956.1\|149990_150740_+\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	6.42122e-104
NZ_GL454139.1\|WP_002364373.1\|150736_151606_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	4.30887e-76
NZ_GL454139.1\|WP_002401815.1\|147501_148647_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	2.81317e-177
NZ_GL454139.1\|WP_002362076.1\|148803_149778_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_GL454139.1\|WP_002362078.1\|152573_154112_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.093e-165
NZ_GL454139.1\|WP_002378495.1\|167870_169577_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	3.94445e-89
NZ_GL454139.1\|WP_002401817.1\|159790_161281_+\|glucosyltransferase-domain-containing-protein	gnl\|CDD\|372986	pfam14264, Glucos_trans_II, Glucosyl transferase GtrII. This family includes glucosyl transferase II from the Shigella phage SfII, which mediates seroconversion of S. flexneri when the phage is integrated into the host chromosome.	3.7449e-32
NZ_GL454139.1\|WP_002360002.1\|151592_152519_+\|metal-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238557	cd01137, PsaA, Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	2.69531e-124
NZ_GL454139.1\|WP_002359998.1\|156542_157223_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	2.31083e-88
NZ_GL454139.1\|WP_002391464.1\|163240_164521_-\|aminoacyltransferase	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	3.0293e-176
NZ_GL454139.1\|WP_002378488.1\|157241_158312_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	7.54405e-167
NZ_GL454139.1\|WP_002378487.1\|154481_155675_-\|amidohydrolase	gnl\|CDD\|349940	cd08019, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0

>NZ_GL454139.1|WP_002378488.1|157241_158312_-|methionine-ABC-transporter-ATP-binding-protein
MIELKNISVTFQQKKQEIQAVQDVSLTIDKGDIYGIVGYSGAGKSTLVRVINLLQRPTAGTVIINKENILTFSKKELRQQRKKIGMIFQHFNLMKERTIFRNIDFSLKYSGLSKSERRQKISHLLELVGLSEKRDAYPSQLSGGQKQRVAIARALANDPEILLCDEATSALDPKTTGQILALLKKLNQELNLTIVLITHEMQVVKEICNKVAVMENGCVVESNDIVSIFSQPQQPLTKDFIRTATHIDQALTTILEHPKLADLDKNQELIEFSYVGDQTNEPLIAQLYSQYQVYTNILYGNVEIVQNVPIGHLIVVLSGDEAQRQQALTYLAKQGVRTNVLKTYQQTKQKQNLQVI
>NZ_GL454139.1|WP_002359998.1|156542_157223_-|ABC-transporter-permease
MYQLFEKYFPNVVQLKQEFLQSTWETLYMVFWTALIAGVLGVLLGVVLVSTGPSGVLKNPPLYSVLEKIINVCRSIPFIIMLALIQPLTRILAGTTIGTTAALVPLVIGVIPFFARQIENALLEVDPGVIEAAEAMGTSPLGIIFRVYLIEGLPSIIRVSAVTIINLIGLTAMAGAIGAGGLGNLAITRGYNRFQTDVTFMATLIILIMVFISQAISNQLIKKTSH
>NZ_GL454139.1|WP_002366917.1|155689_156523_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKFSKLIGLIGVLAFTIAGCASGSAKDTKTETVKLGVVGTKNDEWESVKDRLKKKNIDLQLVEFTDYTQPNAALAEKEIDLNAFQHQIFLDNYNKEHGTKLVSIGNTVNAPLGIYANKLKDITKIKDGGEIAIPNDPTNGGRALILLQTAGLIKVDPAKQQLPTVSDITENKRQLKITELDATQTARALQDVDASVINSGMAVDAGYTPDKDAIFLEPVNEKAKPYVNIVVAREEDQENKLYQKVVEEYQQEETKKVIAETSKGANVPAWETFGKK
>NZ_GL454139.1|WP_002378487.1|154481_155675_-|amidohydrolase
MSTTTIQTIQEAIATEKEWIIHLRRHFHQYPEASLKEYETIKRIKEELLALAIPFVEVGETGVLATIEGGLGAGKTILLRADIDALELPDATGAAYASKNPGLNHACGHDGHAAALLGAAKVLKKHQNTFSGTVKLAFQPAEEIGAGARQFVEGNYLEAIDQVFGIHLDSSVPVGKLVATKGATNASCDIFKIEVSGQSSHVAQPQNGRDAVLAAASIVVELQKIVAREIDPLDSVVVGIGVLQAGTRYNIVANQATIEGTVRTFSQETRQFVLQRVEEIAHEIAQSHRTEIADFSVYAAANPLINEEQATNRAQQVASEIVGFENVVTDHPKSLGADDFADYLAVIPGIYGRVGSRNPENPATHFGHHHEQFDIDERALLLAAEYHIRYALNYLSE
>NZ_GL454139.1|WP_002362078.1|152573_154112_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSILTIEHLTHRFGEKVLYEEASLQVNKGDHLGLTGQNGVGKSTLIKILTGEVLPDEGTIQWQKNCKIGYLDQHVSVEQSLTMVDFLKQAFQELFDKEAKLTKLYEEYSQTASEKLLEQAGKLQTDLDESNFYQIDTIIQDLANGLGLQAIGLDKKLGELSGGQRSKVILAKLLLEAPDVLLLDEPTNYLDDTHIQWLVRYLNNFEGSFLLVSHDYQFLNEVTNCIADIEFGKLTKYTGNVEKSFAQKEQNKQTYLKQYQAQQEKIEKMEAYIRKYKAGNRATMAKSRQKQLDRLERLTPPGSLTKPAIEFPYQGLVATQALTTQKLVVGYREPLLEPLDLMVHVGEKVALKGFNGIGKSTLIKTLTKVIPSLDGEFHYPLNTKIAYFTQDLAWPNEQLTPLDYLSDRFPDTTIKERRSHLARAGLPDKLAMQSLALLSGGEQTKVKLAELMMQTSNLLFLDEPTNHIDEAAKKSLQEAIHVYPGTVFLVSHEADFYEEIVDRVIDIEELVK
>NZ_GL454139.1|WP_002360002.1|151592_152519_+|metal-ABC-transporter-substrate-binding-protein
MKKFSLFFLTLLAGLTLAACGNQAAEKKEKLAIVTTNSILSDLVKNVGEDKIELHSIVPIGTDPHEYEPLPEDIAKASEADILFFNGLNLETGGNGWFNKLMKTAKKVENKDYFSTSKNVTPQYLTSAGQEQTEDPHAWLDIENGIKYVENIRDVLVEKDPKNKDFYTENAKNYTEKLSKLHEEAKAKFADIPDDKKLLVTSEGAFKYFSKAYDLNAAYIWEINTESQGTPEQMTTIIDTIKKSKAPVLFVETSVDKRSMERVSKEVKRPIYDTLFTDSLAKEGTEGDTYYSMMNWNLTKIHDGLMSK
>NZ_GL454139.1|WP_002364373.1|150736_151606_+|metal-ABC-transporter-permease
MIAAFIDGLFRYQFLQNALLTSIIVGLISGVIGSFIILRGMSLMGDAISHAVLPGVAVSYMFGFNYIFGASIFGLLAALSIGFITQKSPLKNDTAIGVVFSSFFALGIIFISFAKSSTDLYHILFGNVLAVADTDILITCVVGVIVLIFVALFYKELQLTSFDPTMAQAYGLNIQFFHYALMFLLTLVAVSSLQTVGTILVIAMLITPAATAYLLTNHLPTMIGLASTFGILSSVIGLFFSYSYNLASGATIVLTAALFFLLAFFFSPKKGLVFVNREKEMEESTNEKI
>NZ_GL454139.1|WP_002356956.1|149990_150740_+|metal-ABC-transporter-ATP-binding-protein
MRKSFNLAVQALTVQYQGRTALNNIHVTIPSGKITGIIGPNGAGKSTFIKGLLGLIKTKERNVLLNNQAIDQQKTTIAYVEQRSALDLSFPISVFETVLLGTYPNLGLLKRPGKKEKQAAMAALKMVQLEDYAQRQIGELSGGQLQRVFIARVLAQGAEVIFLDEPFVGIDMSSEKVIMDILKSLKNQGKMIIIVHHDLHKVSHYFDELIVLKNRLIAAGPVEQTFTAETLQEAYGDLLGDLLIQGVAK
>NZ_GL454139.1|WP_002362076.1|148803_149778_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE
>NZ_GL454139.1|WP_002401815.1|147501_148647_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQMIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKNNGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_GL454139.1|WP_002401817.1|159790_161281_+|glucosyltransferase-domain-containing-protein
MMKQLPTESKKFDLKNWCIENKAYLLLIILIYQVAVLSIGIINFPYLDDNARQVAGMTDFGTTYARWGSEFLSWFVQGSRHLTDLGLTTPILTGLILSLTSILAIYIINDQKISWGSSLVATLIGLNPWFLQCLSFRFDSPYMALSIFCSFLPFYWWQRNSFTFFLVSAFSLFVMFNTYQASSGIYIVIVLFLTFKQLLAGENFIALCKKVALAAIAYLLSIVSYLIELKFVPSATNNIGGSQALPSLHDIPSVAYQNSYHYFSELLNQSNRLWLLLLLLLLVLFFISHLSNSKINLCLSFLYCILYLGLASLLSFGIFIVYSRNIAGDAPRYIYGFAVFVTISMLSLFNNRQVKAIYLTSLLVASLLSYYILSFVLVYSSTLNYQKEAFNRQAAVLTDDLKNVVTNERKKVYLNTFFKNSTVYANTSRNYPILSKIVPPNDGLYFPNYVWFNTSSNLGVEMVPLTDTDMSKNQKVVSNHFYDIYTNNKEIFVFMK
>NZ_GL454139.1|WP_002401818.1|161494_161674_+|hypothetical-protein
MRTRQKKLFLFSIILWLVEFLITRISDSFPGATPLFVVICLIQGILFTYFCLAFFYYPQ
>NZ_GL454139.1|WP_002378492.1|161761_162727_-|hypothetical-protein
MSTIHEFPKNYERFIAQGEEALVEHNQIAALENFQQAYQLQQTPPVNQKIVQLLLEMGEADEALALAEAFQETYFENLETAAIYMQIYSQSRRFIEGYILLKQLLQTKKITLAQQKTLEQQLMQVEEAYQQLETQQIQAIKRNLLVSDQLPVYQQLANIKTSLYLPKPVFVEVAKDLVMNQALSYFAREWFIEELALLQFSEPLTFLWYDNQPQTVLLEGKTGPLNTPIYSEICTELRNRLENDDPIMLQHLEEEIRLHLAYLYPLAETVISDPTIWVWGYLATYYPEYIEKELTEAKGHQIDAVQKVQQAIRTAFTQIML
>NZ_GL454139.1|WP_002356942.1|162902_163193_-|hypothetical-protein
MENQVEVMTYAQLKEIMQVLEANEAITEDTKVFIDTGWDSVQEVAPDAVSIEKVAKFTVADVLTNESFAGYSLEEKAEKMNAEGDLETAIIIRNLY
>NZ_GL454139.1|WP_002391464.1|163240_164521_-|aminoacyltransferase
MLIYLTKKDCELFDMDQFSTLTEQEFTTFAMTHPAGNFLETPEMKHLLERRGWHCEYVGVKREGQLIAACILSKKKVKIGYAFDIDGGILMDYTDKKCVEAFFTGLKKYVKKNDGLYLTFTPNKQICLRDFNGGEVEKVNQETFDYFTSIGFEHQGFDVHNFDGAPRWLFVKDMAGLTEEDLWKSYGKDAKYDIKKTWEYGVTTRELRYEELPLFKKLTEETSARRNFEDKDLAYYQAVYEEFGERAKFMVAELNFATYLENLHEKLRKLQETLNEVNEALIANPKSRKKNNQKREFEDEVRTVRKRIDEAKEMKTSDEPEILAGALFIVHPQEVVYLFSGTYEKYKQYYAPYLIQHKMLTYTVENNIPKYNFYGVDGVFDGSDGVLKFKQSFGGHVEELMGNFQWKAKPMKYALYHALKTIKEKV
>NZ_GL454139.1|WP_002356940.1|164789_166598_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGMIGKENVTESLIQGLTKLEYRGYDSAGICVNDQSQQPHVVKAVGGIADLAAKLTPEIDGTVGIGHTRWATHGEPTVANAHPHVSSDQRFALVHNGVIENFEELKEQFLSGAHLIGDTDTEIVVQLIAHFAENGFSTKDAFKAALAEIKGSYAFALMDKMDPNTIYVAKNKSPLLIGLGEGFNVICSDAMAMIKETNQFVEIVDGEIVTVTADKVVIETPEGQVINREPFEAQLDLNDIEKGTYPFYMLKEIDEQPAVMRKIVQAYTQGEKVTLDEALLEKINQCDRIYIIACGTSYNAGWVGKSLIETIASIPVEVHLSSEFGYNMPILSEKPFFIFLSQSGETADSRQVLVQVNELGHPSLTLTNVAGSTLSREADDTLLLHAGPEIAVASTKAYTAQIAVLAILAKAIGEERQTLAAVSFDVAHELSVVAAVMETLIDEKQQMKALVEDYLTYTRNAFYIGRGVDYYVSMEAALKLKEISYIQAEGFAAGELKHGTIALIEEGTPVIGIVTDAKVAAHTRGNLKEVESRGARNIVIALESLAKPQDQLIIPDVHPLLSALVSIVPGQLLAYYATLQRGYDVDKPRNLAKSVTVE
>NZ_GL454139.1|WP_002359933.1|167040_167874_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MSERQMLGYHPDSTWIHRLNGTSKLVFLIVVSVACMTTYDTRYLLGMSVVSLVLLKLSNIKWHQISFVIKFIAIFSLLNILTVYLFAPEYGVDLYQSRTVIWEGIGRFTLTQEELFYEFNLVLKYFCTIPLALIFLLTTNPSEFASSLNRIGVSYRISYAVALAIRYIPDIQEDFFNISLAQQARGYEMSKKGRLGQRIKGVAQIVLPLILSSLDRIETVSTAMELRRFGQKKNRTWYAQQPFHLRDFSVMLLALCLLGISFWLFHVNGGRFYNPFQ
>NZ_GL454139.1|WP_002378495.1|167870_169577_-|ABC-transporter-ATP-binding-protein
MKKPIITFNNFSFQYHSQSEPTLKGIQLTIYEGEKVLIVGPSGSGKSTLAQCINGLIPNIYEGEIQGTATVAGKNIQETSLFDLSFDVGTVLQDTDGQFIGLTVAEDIAFALENDAVEQAEMKKAVHKWSEIVELNQLLQHRPQDLSGGQKQRVSMAGVLINQSKILLFDEPLANLDPRAGQETMTLIDTIQQETKATVLIIEHRLEDVLCESVDRIIVMNEGAIISDTTPDELLRQDTLTQQGIREPLYVTAMKYAGIDLTQVSHLDKLAEVSGEMVLPKMTQWSVQPSSVSAVKGAELLRLEQVSYQYDRHGEKVLDDFSVTIHHGEMISIVGKNGAGKSTLSKIICGFITPQSGKILWEGQDFSNYSIKERADKIGYVMQNPNQMISKKMIFEEVALGLVLRDVPQAEIEERVTNILHICGLYPFRNWPISALSFGQKKRVTIASILVLEPELLILDEPTAGQDFKHYTEMMTFLEELNRLGVTILMITHDMHLMLEYTTRALVVCDGRLLADATPVAVLTDEKLIQAASLKETSLFTFAKALGLENPLLFTEKFVAYDREVRFG
>NZ_GL454139.1|WP_002356937.1|169677_170229_-|ECF-type-riboflavin-transporter-substrate-binding-protein
MKEKMSVKTIVAIGIGSAVFVILGRFVVIPTGIPNTNLETSYPFLALMSVVFGPVAGGLIGLIGHTLKDFTTYGSAWWSWIICSGIIGIIFGFAGRKMDLQHGEFTTNDMVRFNIFQAFGNIVVWGLIAPSLDILIYSEPASKVFTQGVFATVSNIVAVGIIGTLLMKAYASTRTKKGSLSKD
>NZ_GL454139.1|WP_002356936.1|170458_171814_-|phosphoglucosamine-mutase
MGKYFGTDGVRGIANKELTPELAFKLGRYGGYVLSQHEDSSRKPRVLVGRDTRISGEMLEQALIAGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISASHNPAEDNGIKFFGADGFKLVDDQEAEIEALLDAEEDTLPRPSAEGLGSLDEFPEGLLKYSQFLVQSIPGDLADMTVCLDAANGATATAVNRVFADLETDFYTMGTSPNGLNINDGVGSTHPEALAEMVVEKGADAGLAFDGDGDRIIAVDELGRIIDGDKIMYICAKYLAEKKRLKKDTIVTTVMSNLGFHKAVEEIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMIFLDYNTTGDGMLSGIQLLNVMKQTGKKLSELADEVTIYPQKLVNIRVTDKNGAMEVPAIKAVVEQAEAEMNGEGRILVRPSGTEPLLRVMAEAPTQEKVDYYVDKIAEVVRAEIGVE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_GL454058.1	260-289	0	1.0

1. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to position: 260-289, mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	6418-6447	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	40343-40372	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	CP002493	Enterococcus faecalis 62 plasmid EF62pB, complete sequence	41009-41038	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_LR135294	Enterococcus faecium isolate E7237 plasmid 2	59816-59845	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_LR135204	Enterococcus faecium isolate E7171 plasmid 2	63376-63405	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	55670-55699	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	28811-28840	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NC_006827	Enterococcus faecalis plasmid pCF10, complete sequence	61304-61333	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP028283	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence	6782-6811	0	1.0
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP018066	Enterococcus faecium strain E1 plasmid pE1_230, complete sequence	180982-181011	0	1.0
NZ_GL454139_1	1.15\|138873\|30\|NZ_GL454139\|PILER-CR,CRT	138873-138902	30	NC_028671	Enterococcus phage vB_EfaS_IME197, complete genome	35468-35497	1	0.967
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NZ_CP046399	Bacillus sp. A260 plasmid unnamed11, complete sequence	84399-84423	3	0.88
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	6418-6450	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	40343-40375	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	CP002493	Enterococcus faecalis 62 plasmid EF62pB, complete sequence	41009-41041	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_LR135294	Enterococcus faecium isolate E7237 plasmid 2	59816-59848	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_LR135204	Enterococcus faecium isolate E7171 plasmid 2	63376-63408	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	55670-55702	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	28811-28843	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NC_006827	Enterococcus faecalis plasmid pCF10, complete sequence	61304-61336	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_CP028283	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence	6782-6814	3	0.909
NZ_GL454139_1	1.7\|138936\|33\|NZ_GL454139\|CRISPRCasFinder	138936-138968	33	NZ_CP018066	Enterococcus faecium strain E1 plasmid pE1_230, complete sequence	180979-181011	3	0.909
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NZ_CP018746	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1	5299-5323	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NZ_CP028865	Borreliella garinii strain 20047 plasmid lp36, complete sequence	31705-31729	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NC_001856	Borreliella burgdorferi B31 plasmid lp38, complete sequence	5298-5322	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NZ_CP019853	Borreliella burgdorferi plasmid lp38, complete sequence	5298-5322	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NZ_CP019764	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence	5298-5322	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	NC_017240	Borreliella afzelii PKo plasmid lp32-10, complete sequence	24098-24122	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	KJ608189	UNVERIFIED: Leuconostoc phage LLC-1, partial genome	10099-10123	4	0.84
NZ_GL454139_1	1.1\|138641\|25\|NZ_GL454139\|PILER-CR	138641-138665	25	KT852578	Bacillus phage BMBtp1, complete genome	15759-15783	4	0.84
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	KJ608189	UNVERIFIED: Leuconostoc phage LLC-1, partial genome	10095-10123	5	0.828
NZ_GL454139_1	1.13\|138703\|29\|NZ_GL454139\|CRT	138703-138731	29	NZ_CP051549	Phytobacter diazotrophicus strain UAEU22 plasmid unnamed1	56137-56165	5	0.828
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	CP016195	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence	223010-223039	5	0.833
NZ_GL454139_1	1.15\|138873\|30\|NZ_GL454139\|PILER-CR,CRT	138873-138902	30	NC_019735	Crinalium epipsammum PCC 9333 plasmid pCRI9333.04, complete sequence	24640-24669	6	0.8
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NZ_CP049890	Jeotgalibaca porci strain CCUG 69148 plasmid p_unnamed1, complete sequence	52446-52475	6	0.8
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	MH319764	Marine virus AG-345-P14 Ga0172274_11 genomic sequence	11101-11130	6	0.8
NZ_GL454139_1	1.5\|138765\|33\|NZ_GL454139\|CRISPRCasFinder	138765-138797	33	NC_011265	Borrelia duttonii Ly plasmid pl27, complete sequence	7959-7991	7	0.788
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NZ_CP046399	Bacillus sp. A260 plasmid unnamed11, complete sequence	84399-84427	7	0.759
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	KT852578	Bacillus phage BMBtp1, complete genome	15755-15783	7	0.759
NZ_GL454139_1	1.14\|138769\|29\|NZ_GL454139\|CRT	138769-138797	29	NC_011265	Borrelia duttonii Ly plasmid pl27, complete sequence	7963-7991	7	0.759
NZ_GL454139_1	1.14\|138769\|29\|NZ_GL454139\|CRT	138769-138797	29	NC_007021	Staphylococcus phage Twort, complete genome	73082-73110	7	0.759
NZ_GL454139_1	1.14\|138769\|29\|NZ_GL454139\|CRT	138769-138797	29	MT151386	Staphylococcus virus Twort, complete genome	115611-115639	7	0.759
NZ_GL454139_1	1.15\|138873\|30\|NZ_GL454139\|PILER-CR,CRT	138873-138902	30	MN855764	Siphoviridae sp. isolate 508, partial genome	26661-26690	7	0.767
NZ_GL454139_1	1.16\|138939\|30\|NZ_GL454139\|PILER-CR,CRT	138939-138968	30	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	109092-109121	7	0.767
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MT074146	Bacteroides phage SJC03, complete genome	702-731	7	0.767
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MN693361	Marine virus AFVG_25M120, complete genome	15458-15487	7	0.767
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MN694366	Marine virus AFVG_250M1050, complete genome	6922-6951	7	0.767
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	3114-3143	7	0.767
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NC_022602	Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR47, complete sequence	46780-46809	7	0.767
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	CP034667	Proteus vulgaris strain PvSC3 plasmid pPvSC3, complete sequence	88090-88119	7	0.767
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	NC_025249	Lactococcus lactis subsp. cremoris MG1363 plasmid pFI430, complete sequence	26320-26349	7	0.767
NZ_GL454139_1	1.9\|139068\|33\|NZ_GL454139\|CRISPRCasFinder	139068-139100	33	NC_025249	Lactococcus lactis subsp. cremoris MG1363 plasmid pFI430, complete sequence	26317-26349	8	0.758
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NZ_CP018746	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1	5295-5323	8	0.724
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NZ_CP028865	Borreliella garinii strain 20047 plasmid lp36, complete sequence	31705-31733	8	0.724
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NC_001856	Borreliella burgdorferi B31 plasmid lp38, complete sequence	5294-5322	8	0.724
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NZ_CP019853	Borreliella burgdorferi plasmid lp38, complete sequence	5294-5322	8	0.724
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NZ_CP019764	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence	5294-5322	8	0.724
NZ_GL454139_1	1.12\|138637\|29\|NZ_GL454139\|CRT	138637-138665	29	NC_017240	Borreliella afzelii PKo plasmid lp32-10, complete sequence	24098-24126	8	0.724
NZ_GL454139_1	1.15\|138873\|30\|NZ_GL454139\|PILER-CR,CRT	138873-138902	30	AP017992	Planktothrix agardhii NIES-204 plasmid plasmid1 DNA, complete sequence	63387-63416	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	303022-303051	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MT939487	Erwinia phage pEa_SNUABM_47, complete genome	166256-166285	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MT939486	Erwinia phage pEa_SNUABM_12, complete genome	166996-167025	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NC_041917	Serratia phage BF, complete genome	166968-166997	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MT939488	Erwinia phage pEa_SNUABM_50, complete genome	166133-166162	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NZ_CP026682	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence	162641-162670	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	MN693354	Marine virus AFVG_25M352, complete genome	31251-31280	8	0.733
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NC_041973	Erwinia phage vB_EamM_RAY, complete genome	119192-119221	8	0.733
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	100420-100449	8	0.733
NZ_GL454139_1	1.18\|139071\|30\|NZ_GL454139\|PILER-CR,CRT	139071-139100	30	MN693692	Marine virus AFVG_250M675, complete genome	38024-38053	8	0.733
NZ_GL454139_1	1.3\|138633\|33\|NZ_GL454139\|CRISPRCasFinder	138633-138665	33	NZ_CP046399	Bacillus sp. A260 plasmid unnamed11, complete sequence	84395-84427	9	0.727
NZ_GL454139_1	1.8\|139002\|33\|NZ_GL454139\|CRISPRCasFinder	139002-139034	33	NZ_CP049890	Jeotgalibaca porci strain CCUG 69148 plasmid p_unnamed1, complete sequence	52446-52478	9	0.727
NZ_GL454139_1	1.8\|139002\|33\|NZ_GL454139\|CRISPRCasFinder	139002-139034	33	MN694366	Marine virus AFVG_250M1050, complete genome	6922-6954	9	0.727
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	NZ_LR214994	Mycoplasma hyopneumoniae strain NCTC10127 plasmid 3	9647-9676	9	0.7
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	AJ748296	Sulfolobus islandicus rudivirus 1 variant XX, complete genome	1976-2005	9	0.7
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	AJ414696	Sulfolobus virus SIRV-1 complete viral genome	1976-2005	9	0.7
NZ_GL454139_1	1.17\|139005\|30\|NZ_GL454139\|PILER-CR,CRT	139005-139034	30	AJ414696	Sulfolobus virus SIRV-1 complete viral genome	30304-30333	9	0.7
NZ_GL454139_1	1.3\|138633\|33\|NZ_GL454139\|CRISPRCasFinder	138633-138665	33	KT852578	Bacillus phage BMBtp1, complete genome	15755-15787	11	0.667

1. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

2. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

3. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to CP002493 (Enterococcus faecalis 62 plasmid EF62pB, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

4. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_LR135294 (Enterococcus faecium isolate E7237 plasmid 2) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

5. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_LR135204 (Enterococcus faecium isolate E7171 plasmid 2) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

6. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

7. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

8. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NC_006827 (Enterococcus faecalis plasmid pCF10, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

9. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP028283 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

10. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP018066 (Enterococcus faecium strain E1 plasmid pE1_230, complete sequence) position: , mismatch: 0, identity: 1.0

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
gataagtattacacatcaaaaaaatgctta	Protospacer
******************************

11. spacer 1.15|138873|30|NZ_GL454139|PILER-CR,CRT matches to NC_028671 (Enterococcus phage vB_EfaS_IME197, complete genome) position: , mismatch: 1, identity: 0.967

gcatcaatcaaaattccctcaatcacataa	CRISPR spacer
gcatcaatcaaaattccctcgatcacataa	Protospacer
********************.*********

12. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NZ_CP046399 (Bacillus sp. A260 plasmid unnamed11, complete sequence) position: , mismatch: 3, identity: 0.88

gtttttaatattgccgtcttttaaa	CRISPR spacer
ttttttaatatagccttcttttaaa	Protospacer
 ********** *** *********

13. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

14. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

15. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to CP002493 (Enterococcus faecalis 62 plasmid EF62pB, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

16. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_LR135294 (Enterococcus faecium isolate E7237 plasmid 2) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

17. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_LR135204 (Enterococcus faecium isolate E7171 plasmid 2) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

18. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

19. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

20. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NC_006827 (Enterococcus faecalis plasmid pCF10, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

21. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP028283 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

22. spacer 1.7|138936|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP018066 (Enterococcus faecium strain E1 plasmid pE1_230, complete sequence) position: , mismatch: 3, identity: 0.909

aacgataagtattacacatcaaaaaaatgctta	CRISPR spacer
cctgataagtattacacatcaaaaaaatgctta	Protospacer
  .******************************

23. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NZ_CP018746 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

24. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NZ_CP028865 (Borreliella garinii strain 20047 plasmid lp36, complete sequence) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

25. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NC_001856 (Borreliella burgdorferi B31 plasmid lp38, complete sequence) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

26. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NZ_CP019853 (Borreliella burgdorferi plasmid lp38, complete sequence) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

27. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NZ_CP019764 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

28. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to NC_017240 (Borreliella afzelii PKo plasmid lp32-10, complete sequence) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tcttttaataatgccttcttttaaa	Protospacer
 .******** **** *********

29. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to KJ608189 (UNVERIFIED: Leuconostoc phage LLC-1, partial genome) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
gtttataatattgccgtctttgtca	Protospacer
**** ****************   *

30. spacer 1.1|138641|25|NZ_GL454139|PILER-CR matches to KT852578 (Bacillus phage BMBtp1, complete genome) position: , mismatch: 4, identity: 0.84

gtttttaatattgccgtcttttaaa	CRISPR spacer
tattttaatattgccctcttttaca	Protospacer
  ************* ******* *

31. spacer 1.12|138637|29|NZ_GL454139|CRT matches to KJ608189 (UNVERIFIED: Leuconostoc phage LLC-1, partial genome) position: , mismatch: 5, identity: 0.828

gtttttaatattgccgtcttttaaataag	CRISPR spacer
gtttataatattgccgtctttgtcagaag	Protospacer
**** ****************   * ***

32. spacer 1.13|138703|29|NZ_GL454139|CRT matches to NZ_CP051549 (Phytobacter diazotrophicus strain UAEU22 plasmid unnamed1) position: , mismatch: 5, identity: 0.828

tcttagaacgctattcggaacgctttaag	CRISPR spacer
tggtggaacggtattcgaaacgctttaag	Protospacer
*  *.***** ******.***********

33. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to CP016195 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence) position: , mismatch: 5, identity: 0.833

aagcaagaatagtaagaactacaaaaatgc	CRISPR spacer
aacgaagaagagtaagtactacaaaaatga	Protospacer
**  ***** ****** ************

34. spacer 1.15|138873|30|NZ_GL454139|PILER-CR,CRT matches to NC_019735 (Crinalium epipsammum PCC 9333 plasmid pCRI9333.04, complete sequence) position: , mismatch: 6, identity: 0.8

gcatcaatcaaaattccctcaatcacataa	CRISPR spacer
gcatcaatcagaatttcctcaatagcttca	Protospacer
**********.****.******* .* * *

35. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP049890 (Jeotgalibaca porci strain CCUG 69148 plasmid p_unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
gtatgttttttctggctctaaattttggaa	Protospacer
*  . ******** *.**************

36. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to MH319764 (Marine virus AG-345-P14 Ga0172274_11 genomic sequence) position: , mismatch: 6, identity: 0.8

aagcaagaatagtaagaact-acaaaaatgc	CRISPR spacer
aagcaagaatagaaagaactaacatgggtg-	Protospacer
************ ******* *** ...**

37. spacer 1.5|138765|33|NZ_GL454139|CRISPRCasFinder matches to NC_011265 (Borrelia duttonii Ly plasmid pl27, complete sequence) position: , mismatch: 7, identity: 0.788

aacttactttcttgatagattctttagccttat	CRISPR spacer
aacttactttcttgaaagatactttagaacttg	Protospacer
*************** **** ******  .*

38. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NZ_CP046399 (Bacillus sp. A260 plasmid unnamed11, complete sequence) position: , mismatch: 7, identity: 0.759

gtttttaatattgccgtcttttaaataag	CRISPR spacer
ttttttaatatagccttcttttaaagtta	Protospacer
 ********** *** *********   .

39. spacer 1.12|138637|29|NZ_GL454139|CRT matches to KT852578 (Bacillus phage BMBtp1, complete genome) position: , mismatch: 7, identity: 0.759

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tattttaatattgccctcttttacatctc	Protospacer
  ************* ******* **

40. spacer 1.14|138769|29|NZ_GL454139|CRT matches to NC_011265 (Borrelia duttonii Ly plasmid pl27, complete sequence) position: , mismatch: 7, identity: 0.759

tactttcttgatagattctttagccttat	CRISPR spacer
tactttcttgaaagatactttagaacttg	Protospacer
*********** **** ******  .*

41. spacer 1.14|138769|29|NZ_GL454139|CRT matches to NC_007021 (Staphylococcus phage Twort, complete genome) position: , mismatch: 7, identity: 0.759

tactttcttgatagattctttagccttat	CRISPR spacer
agctttcttcatagattctttagtgtact	Protospacer
 .******* *************. *  *

42. spacer 1.14|138769|29|NZ_GL454139|CRT matches to MT151386 (Staphylococcus virus Twort, complete genome) position: , mismatch: 7, identity: 0.759

tactttcttgatagattctttagccttat	CRISPR spacer
agctttcttcatagattctttagtgtact	Protospacer
 .******* *************. *  *

43. spacer 1.15|138873|30|NZ_GL454139|PILER-CR,CRT matches to MN855764 (Siphoviridae sp. isolate 508, partial genome) position: , mismatch: 7, identity: 0.767

gcatcaatcaaaattccctcaatcacataa	CRISPR spacer
gaacttaagaaaattcactcaatcacataa	Protospacer
* *.. *  ******* *************

44. spacer 1.16|138939|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gataagtattacacatcaaaaaaatgctta	CRISPR spacer
aaaaatacttacacatcaaaaaaacgcttt	Protospacer
.* **   ****************.****

45. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 7, identity: 0.767

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cttctttttcttttgttctaaattttctat	Protospacer
  *******.*.**************  *

46. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MN693361 (Marine virus AFVG_25M120, complete genome) position: , mismatch: 7, identity: 0.767

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
gacatttttttcttgtgctaaattttcaat	Protospacer
*.. ************ ********* .*

47. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MN694366 (Marine virus AFVG_250M1050, complete genome) position: , mismatch: 7, identity: 0.767

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
tctcttattttcttggtctaaatttttaag	Protospacer
  **** ******** ********** .*.

48. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 7, identity: 0.767

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
tttttctttttcttcttctaaagtttggat	Protospacer
  *.*.******** ******* ******

49. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NC_022602 (Carnobacterium inhibens subsp. gilichinskyi plasmid pWNCR47, complete sequence) position: , mismatch: 7, identity: 0.767

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cgtcagtttttcttgttctaaattagataa	Protospacer
 ***  ******************  . **

50. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to CP034667 (Proteus vulgaris strain PvSC3 plasmid pPvSC3, complete sequence) position: , mismatch: 7, identity: 0.767

aagcaagaatagtaagaactacaaaaatgc	CRISPR spacer
atgagtaaaaagtaagaactacaaaaatgg	Protospacer
* * . .** *******************

51. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to NC_025249 (Lactococcus lactis subsp. cremoris MG1363 plasmid pFI430, complete sequence) position: , mismatch: 7, identity: 0.767

aagcaagaatagtaagaactacaaaaatgc	CRISPR spacer
attaaagaaaaggaagaactacaaaaatcg	Protospacer
*   ***** ** ***************

52. spacer 1.9|139068|33|NZ_GL454139|CRISPRCasFinder matches to NC_025249 (Lactococcus lactis subsp. cremoris MG1363 plasmid pFI430, complete sequence) position: , mismatch: 8, identity: 0.758

--aacaagcaagaatagtaagaactacaaaaatgc	CRISPR spacer
ttaatta--aagaaaaggaagaactacaaaaatcg	Protospacer
  **. *  ***** ** ***************

53. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NZ_CP018746 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaacttt	Protospacer
 .******** **** *********.

54. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NZ_CP028865 (Borreliella garinii strain 20047 plasmid lp36, complete sequence) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaacttt	Protospacer
 .******** **** *********.

55. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NC_001856 (Borreliella burgdorferi B31 plasmid lp38, complete sequence) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaaattt	Protospacer
 .******** **** *********

56. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NZ_CP019853 (Borreliella burgdorferi plasmid lp38, complete sequence) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaaattt	Protospacer
 .******** **** *********

57. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NZ_CP019764 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp38, complete sequence) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaaattt	Protospacer
 .******** **** *********

58. spacer 1.12|138637|29|NZ_GL454139|CRT matches to NC_017240 (Borreliella afzelii PKo plasmid lp32-10, complete sequence) position: , mismatch: 8, identity: 0.724

gtttttaatattgccgtcttttaaataag	CRISPR spacer
tcttttaataatgccttcttttaaacttt	Protospacer
 .******** **** *********.

59. spacer 1.15|138873|30|NZ_GL454139|PILER-CR,CRT matches to AP017992 (Planktothrix agardhii NIES-204 plasmid plasmid1 DNA, complete sequence) position: , mismatch: 8, identity: 0.733

gcatcaatcaaaattccctcaatcacataa	CRISPR spacer
ccggactccataattccctcaatcacataa	Protospacer
 *.    .** *******************

60. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
atacagtttttcttgttctgaattttgggt	Protospacer
.  *  *************.********.

61. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MT939487 (Erwinia phage pEa_SNUABM_47, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cattgttttttcttgtgctaaattttgtgc	Protospacer
 .*. *********** ********** .

62. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MT939486 (Erwinia phage pEa_SNUABM_12, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cattgttttttcttgtgctaaattttgtgc	Protospacer
 .*. *********** ********** .

63. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NC_041917 (Serratia phage BF, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cattgttttttcttgtgctaaattttgtgc	Protospacer
 .*. *********** ********** .

64. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MT939488 (Erwinia phage pEa_SNUABM_50, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cattgttttttcttgtgctaaattttgtgc	Protospacer
 .*. *********** ********** .

65. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP026682 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cctttttttttcttgttctaattcttgttg	Protospacer
  *.***************** *.***  .

66. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to MN693354 (Marine virus AFVG_25M352, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
gtagagtttttcttgttctatattttgcat	Protospacer
*     ************** ****** *

67. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NC_041973 (Erwinia phage vB_EamM_RAY, complete genome) position: , mismatch: 8, identity: 0.733

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
cgtctttttttttggttctaaattaactta	Protospacer
 **********.* **********     *

68. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 8, identity: 0.733

aagcaagaatagtaagaactacaaaaatgc	CRISPR spacer
atactgctatagtaagaactataaaaatga	Protospacer
* .* .  *************.*******

69. spacer 1.18|139071|30|NZ_GL454139|PILER-CR,CRT matches to MN693692 (Marine virus AFVG_250M675, complete genome) position: , mismatch: 8, identity: 0.733

aagcaagaatagtaagaactacaaaaatgc------	CRISPR spacer
aagcaagaatagcaagaact------aagctttatt	Protospacer
************.*******      * **

70. spacer 1.3|138633|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP046399 (Bacillus sp. A260 plasmid unnamed11, complete sequence) position: , mismatch: 9, identity: 0.727

aactgtttttaatattgccgtcttttaaataag	CRISPR spacer
tacattttttaatatagccttcttttaaagtta	Protospacer
 **  ********** *** *********   .

71. spacer 1.8|139002|33|NZ_GL454139|CRISPRCasFinder matches to NZ_CP049890 (Jeotgalibaca porci strain CCUG 69148 plasmid p_unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

aacggtctttttttcttgttctaaattttggaa	CRISPR spacer
ggagtatgttttttctggctctaaattttggaa	Protospacer
.. *  . ******** *.**************

72. spacer 1.8|139002|33|NZ_GL454139|CRISPRCasFinder matches to MN694366 (Marine virus AFVG_250M1050, complete genome) position: , mismatch: 9, identity: 0.727

aacggtctttttttcttgttctaaattttggaa	CRISPR spacer
tgctctcttattttcttggtctaaatttttaag	Protospacer
 .*  **** ******** ********** .*.

73. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to NZ_LR214994 (Mycoplasma hyopneumoniae strain NCTC10127 plasmid 3) position: , mismatch: 9, identity: 0.7

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
ccgctttttttctggttctaacttttattc	Protospacer
   ********** ******* ****.

74. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to AJ748296 (Sulfolobus islandicus rudivirus 1 variant XX, complete genome) position: , mismatch: 9, identity: 0.7

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
ataatttttttctttttctaaatttagtcc	Protospacer
.   ********** ********** *

75. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to AJ414696 (Sulfolobus virus SIRV-1 complete viral genome) position: , mismatch: 9, identity: 0.7

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
ataatttttttctttttctaaatttagtcc	Protospacer
.   ********** ********** *

76. spacer 1.17|139005|30|NZ_GL454139|PILER-CR,CRT matches to AJ414696 (Sulfolobus virus SIRV-1 complete viral genome) position: , mismatch: 9, identity: 0.7

ggtctttttttcttgttctaaattttggaa	CRISPR spacer
ataatttttttctttttctaaatttagtcc	Protospacer
.   ********** ********** *

77. spacer 1.3|138633|33|NZ_GL454139|CRISPRCasFinder matches to KT852578 (Bacillus phage BMBtp1, complete genome) position: , mismatch: 11, identity: 0.667

aactgtttttaatattgccgtcttttaaataag	CRISPR spacer
tttctattttaatattgccctcttttacatctc	Protospacer
  ..  ************* ******* **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

64495 : 116844

Enterococcus_phage(36.36%)

holin,portal,tail,tRNA,head,terminase,integrase,capsid

attL 96835:96850|attR 126330:126345

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002360034.1\|64495_66265_-\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_002362049.1\|66282_67584_-\|tRNA	histidine--tRNA ligase	A0A2K9L0H9	Tupanvirus	1.7e-21	24.2
WP_002378438.1\|67941_68388_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002357079.1\|68411_70625_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A142EZT7	Stenotrophomonas_phage	4.7e-08	38.4
WP_002378439.1\|70839_71592_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002371999.1\|71593_72541_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002383131.1\|72556_73051_-	DUF3013 family protein	NA	NA	NA	NA
WP_002364174.1\|72998_73676_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_002360030.1\|73804_75082_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-105	49.9
WP_002357068.1\|75355_75688_+	hypothetical protein	NA	NA	NA	NA
WP_002357065.1\|76003_76477_+	universal stress protein	NA	NA	NA	NA
WP_002357064.1\|76588_77776_-	acetate kinase	NA	NA	NA	NA
WP_002357063.1\|77800_78808_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002362054.1\|78936_79290_-	hypothetical protein	NA	NA	NA	NA
WP_002378441.1\|79289_79724_-	ComGF family competence protein	NA	NA	NA	NA
WP_002370967.1\|79713_80040_-	type II secretion system protein	NA	NA	NA	NA
WP_002357056.1\|80840_81782_-	ferrochelatase	NA	NA	NA	NA
WP_002378444.1\|82497_82770_-	hypothetical protein	NA	NA	NA	NA
WP_002357053.1\|82841_83042_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.6e-24	80.3
WP_002378445.1\|83894_85154_-	LysM peptidoglycan-binding domain-containing protein	C9E2L1	Enterococcus_phage	3.3e-208	89.2
WP_002378446.1\|85166_85547_-\|holin	phage holin family protein	A0A097QQ04	Enterococcus_phage	1.1e-61	100.0
WP_002368228.1\|85557_85680_-	XkdX family protein	NA	NA	NA	NA
WP_002363385.1\|85681_86077_-	hypothetical protein	NA	NA	NA	NA
WP_002363384.1\|86095_86548_-	hypothetical protein	C0LZY6	Enterococcus_phage	3.3e-17	40.3
WP_002363383.1\|86564_87305_-	hypothetical protein	A0A1X9IGH6	Lactococcus_phage	1.2e-27	34.6
WP_002378447.1\|87310_88756_-\|tail	phage tail protein	A0A1S5SA59	Streptococcus_phage	8.2e-70	36.5
WP_002363380.1\|88755_89478_-	hypothetical protein	A0A1S5SA63	Streptococcus_phage	6.0e-37	37.6
WP_002378448.1\|89474_93929_-\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	3.0e-86	48.1
WP_002366371.1\|93915_94221_-	hypothetical protein	NA	NA	NA	NA
WP_002378449.1\|94289_94688_-	hypothetical protein	NA	NA	NA	NA
WP_002401805.1\|94741_95314_-	hypothetical protein	NA	NA	NA	NA
WP_002378453.1\|95362_95545_-	hypothetical protein	C9E2K1	Enterococcus_phage	1.0e-09	53.3
WP_002364302.1\|95547_96153_-\|tail	phage major tail protein, TP901-1 family	A0A1X9IGH1	Lactococcus_phage	4.5e-22	36.1
WP_002363373.1\|96171_96564_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_002363372.1\|96560_96899_-	HK97 gp10 family phage protein	A0A1X9IGH0	Lactococcus_phage	6.7e-15	40.9
96835:96850	attL	NA	NA	NA	NA
WP_002378454.1\|96895_97171_-	hypothetical protein	NA	NA	NA	NA
WP_002363369.1\|97167_97500_-\|head,tail	phage head-tail connector protein	A0A097BY74	Leuconostoc_phage	3.1e-09	38.9
WP_002378455.1\|97570_98467_-	hypothetical protein	U3PDP8	Lactobacillus_phage	1.9e-69	49.8
WP_002378456.1\|98480_99134_-	hypothetical protein	NA	NA	NA	NA
WP_002378457.1\|99238_100165_-\|capsid	minor capsid protein	A0A097QPZ9	Enterococcus_phage	4.4e-133	100.0
WP_002378458.1\|100157_101642_-\|portal	phage portal protein	A0A097QPZ5	Enterococcus_phage	3.8e-139	99.6
WP_002369892.1\|101641_102925_-\|terminase	PBSX family phage terminase large subunit	Q9AZ91	Lactobacillus_prophage	6.0e-157	65.5
WP_002364295.1\|102905_103340_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.8e-44	64.5
WP_002378459.1\|104072_104522_-	hypothetical protein	NA	NA	NA	NA
WP_002378460.1\|104551_105460_-	hypothetical protein	NA	NA	NA	NA
WP_002357018.1\|106174_106591_-	autolysin	D2IZ17	Enterococcus_phage	1.4e-67	99.3
WP_002378462.1\|107498_107906_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	5.9e-58	84.3
WP_002364343.1\|107902_108760_-	helix-turn-helix domain-containing protein	A0A0P0ICZ8	Lactobacillus_phage	1.1e-24	36.1
WP_002357010.1\|108759_108960_-	hypothetical protein	NA	NA	NA	NA
WP_002364344.1\|108964_109606_-	hypothetical protein	U5U4M2	Lactobacillus_phage	4.8e-30	36.0
WP_002378463.1\|109610_110345_-	ERF family protein	A0A1W6JNQ5	Staphylococcus_phage	3.0e-20	29.9
WP_002357007.1\|110337_110655_-	hypothetical protein	NA	NA	NA	NA
WP_002357006.1\|110874_111429_+	hypothetical protein	V9QKZ3	Oenococcus_phage	2.4e-06	24.5
WP_002378465.1\|112086_112296_-	hypothetical protein	D2IZ57	Enterococcus_phage	8.8e-18	74.2
WP_002357001.1\|112350_112539_+	YegP family protein	NA	NA	NA	NA
WP_002378466.1\|112564_113290_-	phage regulatory protein	A0A0P0IDD0	Lactobacillus_phage	2.2e-31	54.7
WP_002381719.1\|113328_113640_-	hypothetical protein	NA	NA	NA	NA
WP_002364354.1\|113650_113827_-	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
WP_002364355.1\|114138_114471_+	helix-turn-helix transcriptional regulator	A0A097QQ00	Enterococcus_phage	2.6e-35	69.1
WP_002378467.1\|114487_114832_+	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	3.2e-41	71.7
WP_002378468.1\|114867_115596_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	3.2e-22	48.4
WP_002378469.1\|115695_116844_+\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	1.5e-37	30.2
126330:126345	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_GL454051

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CRISPR-Cas detection and classification

Crispr_ID: NZ_GL454051_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_GL454051_1

5081-5212

Orphan

Consensus_repeat	Method
GTTGGTTTTTCCCACTTTCGAACA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_GL454051_1

>merge|NZ_GL454051|1|5081-5212|CRISPRCasFinder
GTTGGTTTTTCCCACTTTCGAACAAAGTACTGGTATTATTGGATTCTTCTGGACGTTGGTTTTTCCCACTTTCGAAAGAAACGCTGATTTTATCATGTTTATCCGAAGGTTGGTTTTTCCCACTTTCGGGAA

>NZ_GL454051|1|1|5081-5212|CRISPRCasFinder
GTTGGTTTTTCCCACTTTCGAACA	AAGTACTGGTATTATTGGATTCTTCTGGAC
GTTGGTTTTTCCCACTTTCGAAAG	AAACGCTGATTTTATCATGTTTATCCGAAG
GTTGGTTTTTCCCACTTTCGGGAA

Protein	Function_ID	Function_description	E-value
NZ_GL454051.1\|WP_002401356.1\|3297_4455_-\|TraB/GumN-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	9.12006e-90
NZ_GL454051.1\|WP_002401358.1\|6244_7027_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.60929e-71
NZ_GL454051.1\|WP_002401355.1\|1658_3284_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0

>NZ_GL454051.1|WP_002401356.1|3297_4455_-|TraB/GumN-family-protein
MEEDIVRLFYKGSEIILIGTSHISTESADLVRKTIQEENPDTICIEWDEKRYKKNIHPDEWDDTDIVKIIKNKQFPVFIFGVIYKLFQKKVSQDMNSLVGKEFVVAVDESKKLNIKFYLIDRDSSLTFKRAWRMLNFREKVKLPYAFGKIFEGAEETEEEVQNLLESENFEPVFEELKESYPNLWEVFVTERDDYLATKIQNTANGKTVAVLGKAHLKGVSDRLKNNQKSDLQKLEIIPPKKIGSKLLEWIIPGILLILLGVSFYQGTQVGIEQLLRWLLWNGGLAALFTIFALGHPLTVLTSLIFAPLATLLPMVSVGVFSAIVEATVRKPKVKDFQTMDLDLQSLKTIYKNRVLRVFLVFFLSSLGGLLGNIIGGLGIVKNLF
>NZ_GL454051.1|WP_002401355.1|1658_3284_-|peptide-ABC-transporter-substrate-binding-protein
MGGLKKVGVLVFVLSVFASCGVNKSTEDSKKANETKVEQIATLSAGTPVQSLDPATAVDQTSVTLLANVMEGLYRLDEKNQPQPAIAAGQPKISNSGKTYTIVIRDGAKWADGTDITADDFVTAWQRVLDPKTASPNVELFAAIKNAKEISIGNQQKETLGVKSKGNKTIEIELEEPTPYFTDLLALTAYFPVQQNAVKEYGKEYGTTKENIITNGAFTLTDLNGVGISDKWTIAKNPKYWDKKHVTMEKIKFQVVKDINTGINLYNDGQLDDAPVAGEYSMQLENNKDFIRELSATTMFLELNQRNKKSITSNKHARQAINFAIDRETISNKILTNGSIPAKGVVPSKLIYNPKTGKDFTNSSLVFLDKSKAKDSWEKAKKELKGTDLSIDIMVNEEDLSKKLGEYLQNELQDTLDGLKVSVTAVPATLQTERLNSGNFMIALSGWQADFADPVSFLANFESKSSLNHGGYANEEYDKLLKNNTSKRLQELKDAEKLIIEDAGVIPLLQIGNAKLRNPKIAEIIVHTIGAKYDYKNMQIK
>NZ_GL454051.1|WP_002401354.1|644_1625_+|hypothetical-protein
MVLFQPKLKECIVLDYKELLEILRKDLNFKKIDLYQEKSNKTRYREIELGEKSPTIEELISFTDTLGIRLSEFLFRGNITPLEASYYGKRKLEVSSLINDFPELERQFPEIYKNRFKNLQCYTLFTICLVISKSLNKSLYTFKNKDVRELKNFYKNREIIIGADYAILSHLHMAVSEHLNELDFLVEKLFPIKQSHGDIHDYAVQICIKNAVTVFLEKKDFDKVDYYLEQFDIVRKTPSFILDGNINLEMIYLRHLKNFLQNRNMEEYLKAVNIVNLFFELGEEVTYKALVKEVTEIARKENFEVPSSLNLIGDTIKNADFLKTRK
>NZ_GL454051.1|WP_002360663.1|5895_6252_-|hypothetical-protein
MSNNRGKSAAERLLGAGKEDTNPTKATTSNEKELKTTHEHIVMNKKNIEKLIKQQGNSKRNADSIRINPILANALKYWTSIGEPEKSKPDVIEETLLKSIPEEYLIKGYEMAKKQNKI
>NZ_GL454051.1|WP_002401358.1|6244_7027_-|ParA-family-protein
MARIISVANQKGGVSKTTTSINLGAALHFTFNKSVLVIDMDPQGNATDNFGFDIDGTNVPTIYEVLKDETSITEAILNYKGIDVIPADIALSSAEREFTQVGSEHRLKRVLQPIEENYDYIIIDCPPSLGILTVNAFTVSDEIIIPVEAAYFSLKGLVKLNETIETVKEYTNESLIIRGVLFTKYNERFNISKEMNKTANQISDALHVNIFDTYIRRTITVDEAQAAGSDLISFNKTSTAEDDYIQFTKEFLEKVGDLNE
>NZ_GL454051.1|WP_002401360.1|7272_7569_-|replication-control-protein-PrgN
MPRKTFVYPHPINTFIIKQLGITVEEFCELHAFSQGTVSSWITRNKKIETLPISFIYSLSLSASKTMDQVYSDLLKLQDDYLLHLERHRRTKKIIDEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5073-5102	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	602-631	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	515-544	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33709-33738	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7643-7672	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66171-66200	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12176-12205	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	503-532	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60906-60935	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92754-92783	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	503-532	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5526-5555	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43889-43918	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83505-83534	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9536-9565	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4944-4973	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	827-856	0	1.0
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66225-66254	0	1.0
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	449-478	0	1.0
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	748-777	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5019-5048	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	548-577	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	461-490	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33655-33684	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	449-478	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5472-5501	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43943-43972	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83451-83480	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	694-723	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9482-9511	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4998-5027	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	773-802	1	0.967
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7697-7726	2	0.933
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12230-12259	2	0.933
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60960-60989	2	0.933
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92808-92837	2	0.933
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NZ_CP034685	Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence	63364-63393	5	0.833
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31963-31992	6	0.8
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	MT711976	Streptomyces phage Coruscant, complete genome	87401-87430	7	0.767
NZ_GL454051_1	1.1\|5105\|30\|NZ_GL454051\|CRISPRCasFinder	5105-5134	30	JQ660954	Clostridium phage PhiS63, complete genome	22890-22919	9	0.7
NZ_GL454051_1	1.2\|5159\|30\|NZ_GL454051\|CRISPRCasFinder	5159-5188	30	NC_015250	Acinetobacter phage 133, complete genome	121681-121710	9	0.7

1. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

2. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

3. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

4. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

5. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

6. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

7. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

8. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

9. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

10. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

11. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

12. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

13. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

14. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

15. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

16. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

17. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

18. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgctgattttatcatgtttatccgaag	Protospacer
******************************

19. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgctgattttatcatgtttatccgaag	Protospacer
******************************

20. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

aagtactggtattattggattcttctggac	CRISPR spacer
aagtcctggtattattggattcttctggac	Protospacer
**** *************************

21. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****.************************

22. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

23. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

24. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

25. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

26. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

27. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

28. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

29. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****.************************

30. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****.************************

31. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

32. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******.***********************

33. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**.***********************

34. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**.***********************

35. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**.***********************

36. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**.***********************

37. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NZ_CP034685 (Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence) position: , mismatch: 5, identity: 0.833

aaacgctgattttatcatgtttatccgaag---	CRISPR spacer
aaacgttgatttaatcatgtttat---aagttt	Protospacer
*****.****** ***********   ***

38. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 6, identity: 0.8

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattaaaggattcttcaaaat	Protospacer
**************  ********* ..*.

39. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 7, identity: 0.767

aagtactggtattattggattcttctggac	CRISPR spacer
acagagtggttttattggcttcttctggat	Protospacer
* . * **** ******* **********.

40. spacer 1.1|5105|30|NZ_GL454051|CRISPRCasFinder matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 9, identity: 0.7

aagtactggtattattggattcttctggac	CRISPR spacer
ttgtactgatattattggtttcttcgtttt	Protospacer
  ******.********* ******    .

41. spacer 1.2|5159|30|NZ_GL454051|CRISPRCasFinder matches to NC_015250 (Acinetobacter phage 133, complete genome) position: , mismatch: 9, identity: 0.7

aaacgctgattttatcatgtttatccgaag	CRISPR spacer
gtaccctgatattatcatgtttatcgatga	Protospacer
. ** ***** ************** . ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_GL454079

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

303899 : 324317

Enterococcus_phage(37.5%)

tRNA,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002360474.1\|303899_304496_-	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	1.5e-22	37.1
WP_002363808.1\|304495_305446_-	riboflavin biosynthesis protein RibF	A0A1V0SD03	Indivirus	1.2e-05	28.7
WP_002378252.1\|305471_306392_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_002401525.1\|306546_307671_-	SH3 domain-containing protein	A0A139ZVY1	Enterococcus_phage	1.2e-76	44.3
WP_002357842.1\|307789_308185_-\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_002378249.1\|308208_309978_-	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.2e-142	62.2
WP_002378248.1\|310010_311468_-\|tail	phage tail protein	C9E2K6	Enterococcus_phage	9.5e-175	47.5
WP_002378247.1\|311480_312407_-\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	4.1e-147	78.6
WP_002401527.1\|312408_315342_-	hypothetical protein	A0A1U9WR55	Streptococcus_virus	2.8e-08	25.1
WP_002392533.1\|315331_315625_-	hypothetical protein	NA	NA	NA	NA
WP_002377707.1\|315717_316077_-\|tail	tail assembly chaperone	A0A2P1JTV4	Anoxybacillus_phage	2.8e-11	36.0
WP_002378245.1\|316109_316622_-\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	3.0e-35	49.4
WP_002401528.1\|316634_317051_-	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|317272_317680_-	RinA family phage transcriptional activator	E9LUP5	Lactobacillus_phage	3.3e-16	38.4
WP_002363798.1\|317699_318092_-	hypothetical protein	NA	NA	NA	NA
WP_002378242.1\|318158_319001_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.4e-29	30.3
WP_002401529.1\|319019_319694_-	DnaD domain protein	A0A1X9I617	Streptococcus_phage	9.5e-21	32.7
WP_002361687.1\|320170_320653_+	helix-turn-helix transcriptional regulator	R9QTP6	Staphylococcus_phage	1.5e-20	48.6
WP_002382232.1\|320687_321173_+	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002401530.1\|321232_321463_-	hypothetical protein	NA	NA	NA	NA
WP_002360497.1\|321545_321896_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002401531.1\|321920_324317_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_GL454094

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_GL454094_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_GL454094_1

82794-82867

Orphan

Consensus_repeat	Method
GTTTTTCTGTTGCTCACCAACTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_GL454094_1

>merge|NZ_GL454094|1|82794-82867|CRISPRCasFinder
GTTTTTCTGTTGCTCACCAACTATTGGCTCTACGTCCAATTCTATATCGAGTTTTTCTGTTGCTCGCCAACTAT

>NZ_GL454094|1|1|82794-82867|CRISPRCasFinder
GTTTTTCTGTTGCTCACCAACTAT	TGGCTCTACGTCCAATTCTATATCGA
GTTTTTCTGTTGCTCGCCAACTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_GL454094.1\|WP_002381060.1\|80400_81372_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_GL454094.1\|WP_002360992.1\|92883_93750_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_GL454094.1\|WP_002401678.1\|68538_69807_+\|competence/damage-inducible-protein-A	unknown	unknown	gnl\|CDD\|234789
NZ_GL454094.1\|WP_002378823.1\|88744_89452_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_GL454094.1\|WP_002401680.1\|87968_88649_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_GL454094.1\|WP_002378827.1\|79101_79656_+\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NZ_GL454094.1\|WP_002354875.1\|83189_83840_-\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NZ_GL454094.1\|WP_002359021.1\|93874_94087_+\|hypothetical-protein	unknown	unknown	unknown
NZ_GL454094.1\|WP_002368461.1\|90150_91419_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_GL454094.1\|WP_002354883.1\|89492_89942_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_GL454094.1\|WP_002378825.1\|83854_86599_-\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NZ_GL454094.1\|WP_002354864.1\|73079_73877_+\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NZ_GL454094.1\|WP_002354866.1\|73964_74336_+\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|226923
NZ_GL454094.1\|WP_002354863.1\|71363_72920_+\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_GL454094.1\|WP_002354868.1\|76944_79077_+\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NZ_GL454094.1\|WP_002354871.1\|79788_80226_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_GL454094.1\|WP_002378828.1\|74336_76913_+\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_GL454094.1\|WP_002354877.1\|86859_87573_+\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_GL454094.1\|WP_002354885.1\|91411_92716_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_GL454094.1\|WP_002354860.1\|69920_70967_+\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476

Protein	Function_ID	Function_description	E-value
NZ_GL454094.1\|WP_002381060.1\|80400_81372_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_GL454094.1\|WP_002360992.1\|92883_93750_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	8.53832e-35
NZ_GL454094.1\|WP_002401678.1\|68538_69807_+\|competence/damage-inducible-protein-A	gnl\|CDD\|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NZ_GL454094.1\|WP_002378823.1\|88744_89452_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.3494e-16
NZ_GL454094.1\|WP_002401680.1\|87968_88649_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	6.52526e-09
NZ_GL454094.1\|WP_002378827.1\|79101_79656_+\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	3.23253e-85
NZ_GL454094.1\|WP_002354875.1\|83189_83840_-\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	7.1375e-106
NZ_GL454094.1\|WP_002368461.1\|90150_91419_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.21959e-51
NZ_GL454094.1\|WP_002354883.1\|89492_89942_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NZ_GL454094.1\|WP_002378825.1\|83854_86599_-\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	1.11964e-173
NZ_GL454094.1\|WP_002354864.1\|73079_73877_+\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NZ_GL454094.1\|WP_002354866.1\|73964_74336_+\|YlbF-family-regulator	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	8.72333e-15
NZ_GL454094.1\|WP_002354863.1\|71363_72920_+\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_GL454094.1\|WP_002354868.1\|76944_79077_+\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NZ_GL454094.1\|WP_002354871.1\|79788_80226_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93
NZ_GL454094.1\|WP_002378828.1\|74336_76913_+\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_GL454094.1\|WP_002354877.1\|86859_87573_+\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.92052e-137
NZ_GL454094.1\|WP_002354885.1\|91411_92716_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.18356e-85
NZ_GL454094.1\|WP_002354860.1\|69920_70967_+\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0

>NZ_GL454094.1|WP_002381060.1|80400_81372_+|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NZ_GL454094.1|WP_002354871.1|79788_80226_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NZ_GL454094.1|WP_002378827.1|79101_79656_+|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPAFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NZ_GL454094.1|WP_002354868.1|76944_79077_+|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAVDSENHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSATSQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NZ_GL454094.1|WP_002378828.1|74336_76913_+|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKERQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVALIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPISVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NZ_GL454094.1|WP_002354866.1|73964_74336_+|YlbF-family-regulator
MEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NZ_GL454094.1|WP_002354864.1|73079_73877_+|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NZ_GL454094.1|WP_002354863.1|71363_72920_+|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NZ_GL454094.1|WP_002354860.1|69920_70967_+|recombinase-RecA
MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLALDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAEKLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKDLISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEGQEELPLDE
>NZ_GL454094.1|WP_002401678.1|68538_69807_+|competence/damage-inducible-protein-A
MLLEKGKSMKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQVVAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMFQQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATEEKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISHELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTIAECFHFNRDRNYIRQSAVMRGLDLLRRRIINKK
>NZ_GL454094.1|WP_002354875.1|83189_83840_-|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGISIDETFNETLKGISRMDSLDRILAHGHRENAFTPAEKEALAQQKNDHYVQLLEHLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NZ_GL454094.1|WP_002378825.1|83854_86599_-|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPEDFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLAAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAIMIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTTSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NZ_GL454094.1|WP_002354877.1|86859_87573_+|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWTEGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NZ_GL454094.1|WP_002401680.1|87968_88649_+|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQATTTGNTPVSVGVEGGVLPEGNYGGAIDPDPNTLNSDFDLLYIPRSISFAKTAISDDLSSIKSSSYANYAVGDLRGTKEGWHVTATILEMVNGGDKLAGAVSFNQVGYVAYYDEVDNRFKVESVGSFNSSPVAPEFPTSRSITIGGGALLVGNAVSGKGQGMWNSYMTDPTLNITTPYQQIKAGTYTGEIAWNLVAGPSV
>NZ_GL454094.1|WP_002378823.1|88744_89452_+|WxL-domain-containing-protein
MKKKIMASLLVGSAVVGASLAPLSAQAVTTGNTPVQVEFGGGTLPDGNSKDGNSVDPDPEGSNSNFDLLFIPREFDFGTLSISDDLTQPIFNKADHLNGEDREGVGVGDLRGTKEGWHLTAQSSGLTQGSENLQGTIAVRQVYSNVLRYDETTNEFTSYGSILETAPNIPIRNNWTMDLGGDAKLLANATAGNGQGLWKIGMWSTSLTITTSAYGIKAGNYTGNITWNLVAGPSI
>NZ_GL454094.1|WP_002354883.1|89492_89942_-|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NZ_GL454094.1|WP_002368461.1|90150_91419_+|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNQLMPQTMLTAEEWIARINAVTISEIQEVAKRLELQAIFFLEGETEND
>NZ_GL454094.1|WP_002354885.1|91411_92716_+|insulinase-family-protein
MIKKDYAQIKETLYTETLANGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETLIREEGLSRFYMYPKGETEQ
>NZ_GL454094.1|WP_002360992.1|92883_93750_+|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETETTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NZ_GL454094.1|WP_002359021.1|93874_94087_+|hypothetical-protein
MLKIVNKKFNLITIFSIALLVMGFLIVGLQLYFYFIYGSKFLDSITLIGMINLGLGYYQLFLKKGKNISE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_GL454149

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NZ_GL454149.1|WP_002401839.1|1972_2302_-|hypothetical-protein

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Acr_ID: NZ_GL454149.1|WP_025188019.1|2315_2930_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_GL454149.1|WP_002401839.1|1972_2302_-|hypothetical-protein

1972_2302_-

109 aa aa

AcrIIA17

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3633\|WP_002401839.1\|AcrIIA17\|II-A\|Verified\|Enterococcus-faecalis	1.0	1	1.0

HTH_49

Identity	Hit_domain_coverage
NA	NA

NZ_GL454149.1|WP_025188019.1|2315_2930_-|hypothetical-protein

2315_2930_-

204 aa aa

AcrIIA16

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3632\|WP_025188019.1\|AcrIIA16\|II-A\|Verified\|Enterococcus-faecalis	1.0	1	1.0

HTH_49

Identity	Hit_domain_coverage
NA	NA

9. NZ_GL454080

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

77547 : 85468

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|77547_78606_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002361357.1\|78605_79562_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.5e-23	33.9
WP_002355796.1\|79602_80673_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002355797.1\|81072_81594_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|81707_81908_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|81968_82328_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002393469.1\|82374_82755_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_002361363.1\|82822_83182_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002368164.1\|83249_83744_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002378095.1\|83761_84277_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	49.1
WP_002378096.1\|84292_85468_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.1e-86	48.0

DBSCAN-SWA_2

135928 : 153455

Streptococcus_phage(100.0%)

integrase

attL 141898:141912|attR 154231:154245

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000420682.1\|135928_136243_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|136258_136645_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|136673_138059_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|138061_138214_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|138236_139442_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|139484_139706_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|139822_140320_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|140294_140801_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|140784_143232_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
141898:141912	attL	NA	NA	NA	NA
WP_000804748.1\|143234_145412_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|145408_146410_+	bifunctional lysozyme/C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224318.1\|146406_147339_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_073459231.1\|147583_147700_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_002364936.1\|147715_149635_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	94.5
WP_002319681.1\|149757_149925_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	7.3e-15	66.0
WP_001227347.1\|149984_150338_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|150842_151265_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|151261_151492_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|151952_152156_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|152237_153455_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
154231:154245	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

10. NZ_GL454052

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

115115 : 123759

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002360141.1\|115115_115688_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.2e-25	35.1
WP_002360140.1\|115684_116716_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	8.2e-56	44.4
WP_002401381.1\|116717_118157_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-49	33.2
WP_002378402.1\|118132_120352_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	9.7e-147	39.9
WP_002357272.1\|120348_121023_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|121023_121275_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002378403.1\|121288_122002_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	3.3e-48	43.0
WP_002397378.1\|122153_123278_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002378405.1\|123270_123759_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.4e-19	42.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage