CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_ANDC01000010	Streptococcus agalactiae CCUG 29782 ctg120000959607, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000018	Streptococcus agalactiae CCUG 29782 ctg120000959615, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_ANDC01000002	Streptococcus agalactiae CCUG 29782 ctg120000959599, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000016	Streptococcus agalactiae CCUG 29782 ctg120000959613, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000004	Streptococcus agalactiae CCUG 29782 ctg120000959601, whole genome shotgun sequence	0 crisprs	NA	0	0	1
NZ_ANDC01000009	Streptococcus agalactiae CCUG 29782 ctg120000959606, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000021	Streptococcus agalactiae CCUG 29782 ctg120000959618, whole genome shotgun sequence	0 crisprs	cas3,csa3	0	1	0
NZ_ANDC01000024	Streptococcus agalactiae CCUG 29782 ctg120000959621, whole genome shotgun sequence	0 crisprs	NA	0	2	0
NZ_ANDC01000023	Streptococcus agalactiae CCUG 29782 ctg120000959620, whole genome shotgun sequence	1 crisprs	csn2,cas2,cas1,cas9	12	0	0
NZ_ANDC01000020	Streptococcus agalactiae CCUG 29782 ctg120000959617, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000005	Streptococcus agalactiae CCUG 29782 ctg120000959602, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000011	Streptococcus agalactiae CCUG 29782 ctg120000959608, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000001	Streptococcus agalactiae CCUG 29782 ctg120000959567, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000007	Streptococcus agalactiae CCUG 29782 ctg120000959604, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000006	Streptococcus agalactiae CCUG 29782 ctg120000959603, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000003	Streptococcus agalactiae CCUG 29782 ctg120000959600, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000013	Streptococcus agalactiae CCUG 29782 ctg120000959610, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000019	Streptococcus agalactiae CCUG 29782 ctg120000959616, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000017	Streptococcus agalactiae CCUG 29782 ctg120000959614, whole genome shotgun sequence	0 crisprs	cas3	0	0	0
NZ_ANDC01000015	Streptococcus agalactiae CCUG 29782 ctg120000959612, whole genome shotgun sequence	1 crisprs	DEDDh,WYL	0	2	0
NZ_ANDC01000012	Streptococcus agalactiae CCUG 29782 ctg120000959609, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_ANDC01000008	Streptococcus agalactiae CCUG 29782 ctg120000959605, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_ANDC01000022	Streptococcus agalactiae CCUG 29782 ctg120000959619, whole genome shotgun sequence	1 crisprs	csm6	0	0	0
NZ_ANDC01000014	Streptococcus agalactiae CCUG 29782 ctg120000959611, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NZ_ANDC01000004.1|WP_000384271.1|6341_6668_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_ANDC01000004.1|WP_000384271.1|6341_6668_-|hypothetical-protein

6341_6668_-

108 aa aa

AcrIIA21

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3639\|WP_000384271.1\|AcrIIA21\|II-A\|Verified\|Streptococcus	1.0	1	1.0

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_ANDC01000023_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANDC01000023_1

69538-70431

TypeII

II-A,II-B:II-A

Consensus_repeat	Method
GTTTTGGAACCATTCGAAACANCACAGCTCTAAAAC	CRT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	PILER-CR

13 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_ANDC01000023_1

>merge|NZ_ANDC01000023|1|69538-70431|CRT,CRISPRCasFinder,PILER-CR
TGGTGCCCTAGCATAATAACAGCACAGCTTTAAAACATCAGTACCAACAAATGATTTTGTACCATCGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTCAGCATTCGGCATTGATATTTTCCCCTCTGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACAAATGTTCTTTTTTAAAATCTTTCATGTTCGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACGGTGGACAAGCTAACCCACAAGAAACTGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACCTAGCTTTATTTATCCCGTTGCGGATGTTTGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACGAAGTAAAAGATATTTATGCAGAAGTGATTGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACTCCGCAAGATGAAACAGATATCTCTTTAAAGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACCTTGAGGCGGTATCTCTCATAAAATGATTAGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACAGCTCTAAATCAACATATCCATCAACTTCAGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACCCTACACACTCGTCTCACGTACTGTTGACAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACATAGTCATCCATCATAACGACTGGTGTGATGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACGAAATTCAAACTGCTTGTAAAATCTCCAGCGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACCATACATGTATGTAAGTGGTAAGAGTTTTTGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_ANDC01000023|1|1|69538-70431|CRT
TGGTGCCCTAGCATAATAACAGCACAGCTTTAAAAC	ATCAGTACCAACAAATGATTTTGTACCATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TCAGCATTCGGCATTGATATTTTCCCCTCT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AAATGTTCTTTTTTAAAATCTTTCATGTTC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACGGTGGACAAGCTAACCCACAAGAAACT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAGCTTTATTTATCCCGTTGCGGATGTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GAAGTAAAAGATATTTATGCAGAAGTGATT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCCGCAAGATGAAACAGATATCTCTTTAAA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTTGAGGCGGTATCTCTCATAAAATGATTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGCTCTAAATCAACATATCCATCAACTTCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CCTACACACTCGTCTCACGTACTGTTGACA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATAGTCATCCATCATAACGACTGGTGTGAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	GAAATTCAAACTGCTTGTAAAATCTCCAGC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CATACATGTATGTAAGTGGTAAGAGTTTTT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_ANDC01000023|1|1|69604-70431|CRISPRCasFinder
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TCAGCATTCGGCATTGATATTTTCCCCTCT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AAATGTTCTTTTTTAAAATCTTTCATGTTC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACGGTGGACAAGCTAACCCACAAGAAACT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAGCTTTATTTATCCCGTTGCGGATGTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GAAGTAAAAGATATTTATGCAGAAGTGATT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCCGCAAGATGAAACAGATATCTCTTTAAA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTTGAGGCGGTATCTCTCATAAAATGATTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGCTCTAAATCAACATATCCATCAACTTCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CCTACACACTCGTCTCACGTACTGTTGACA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATAGTCATCCATCATAACGACTGGTGTGAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	GAAATTCAAACTGCTTGTAAAATCTCCAGC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CATACATGTATGTAAGTGGTAAGAGTTTTT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_ANDC01000023|1|1|69736-70431|PILER-CR
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACGGTGGACAAGCTAACCCACAAGAAACT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAGCTTTATTTATCCCGTTGCGGATGTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GAAGTAAAAGATATTTATGCAGAAGTGATT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCCGCAAGATGAAACAGATATCTCTTTAAA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTTGAGGCGGTATCTCTCATAAAATGATTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGCTCTAAATCAACATATCCATCAACTTCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CCTACACACTCGTCTCACGTACTGTTGACA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATAGTCATCCATCATAACGACTGGTGTGAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	GAAATTCAAACTGCTTGTAAAATCTCCAGC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CATACATGTATGTAAGTGGTAAGAGTTTTT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANDC01000023.1\|WP_000665410.1\|62051_62486_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_ANDC01000023.1\|WP_000621139.1\|62485_62950_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_ANDC01000023.1\|WP_001875996.1\|57302_57884_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_ANDC01000023.1\|WP_000168894.1\|59107_61900_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_ANDC01000023.1\|WP_000590706.1\|70531_71197_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_ANDC01000023.1\|WP_000929490.1\|71521_72391_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_ANDC01000023.1\|WP_000914658.1\|79072_80203_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_ANDC01000023.1\|WP_001056394.1\|55924_56536_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_ANDC01000023.1\|WP_000180008.1\|62958_63618_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_ANDC01000023.1\|WP_001019133.1\|66596_68429_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_ANDC01000023.1\|WP_000159235.1\|80699_81071_-\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_ANDC01000023.1\|WP_000323544.1\|77560_78331_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_ANDC01000023.1\|WP_000653350.1\|76914_77571_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_ANDC01000023.1\|WP_001241816.1\|80294_80675_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_ANDC01000023.1\|WP_001040103.1\|72392_76526_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_ANDC01000023.1\|WP_000678286.1\|63717_66351_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|380193
NZ_ANDC01000023.1\|WP_000438311.1\|68564_68981_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_ANDC01000023.1\|WP_000523795.1\|78331_79069_-\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_ANDC01000023.1\|WP_000065320.1\|58004_59108_-\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_ANDC01000023.1\|WP_000122197.1\|71183_71525_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043

Protein	Function_ID	Function_description	E-value
NZ_ANDC01000023.1\|WP_000665410.1\|62051_62486_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
NZ_ANDC01000023.1\|WP_000621139.1\|62485_62950_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.90455e-18
NZ_ANDC01000023.1\|WP_001875996.1\|57302_57884_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	3.28709e-71
NZ_ANDC01000023.1\|WP_000168894.1\|59107_61900_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_ANDC01000023.1\|WP_000590706.1\|70531_71197_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.61399e-122
NZ_ANDC01000023.1\|WP_000929490.1\|71521_72391_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	5.3759e-138
NZ_ANDC01000023.1\|WP_000914658.1\|79072_80203_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_ANDC01000023.1\|WP_001056394.1\|55924_56536_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
NZ_ANDC01000023.1\|WP_000180008.1\|62958_63618_-\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	1.30028e-33
NZ_ANDC01000023.1\|WP_001019133.1\|66596_68429_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_ANDC01000023.1\|WP_000159235.1\|80699_81071_-\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	7.7979e-28
NZ_ANDC01000023.1\|WP_000323544.1\|77560_78331_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_ANDC01000023.1\|WP_000653350.1\|76914_77571_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.6374e-51
NZ_ANDC01000023.1\|WP_001241816.1\|80294_80675_-\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_ANDC01000023.1\|WP_001040103.1\|72392_76526_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_ANDC01000023.1\|WP_000678286.1\|63717_66351_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	8.03849e-22
NZ_ANDC01000023.1\|WP_000438311.1\|68564_68981_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	2.94262e-78
NZ_ANDC01000023.1\|WP_000523795.1\|78331_79069_-\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_ANDC01000023.1\|WP_000065320.1\|58004_59108_-\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.44123e-105
NZ_ANDC01000023.1\|WP_000122197.1\|71183_71525_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.70123e-50

>NZ_ANDC01000023.1|WP_000438311.1|68564_68981_-|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIEVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>NZ_ANDC01000023.1|WP_001019133.1|66596_68429_-|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_ANDC01000023.1|WP_000678286.1|63717_66351_-|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHPDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKKQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQNNSHYRVNSSKIAGLHHPTSDGFLFNGQGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKVDSKKQSPSSKKPRTENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLASLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_ANDC01000023.1|WP_000180008.1|62958_63618_-|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKG
>NZ_ANDC01000023.1|WP_000621139.1|62485_62950_-|GNAT-family-N-acetyltransferase
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_ANDC01000023.1|WP_000665410.1|62051_62486_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>NZ_ANDC01000023.1|WP_000168894.1|59107_61900_-|cation-transporting-P-type-ATPase
MASTNNVSDTNTCFAKEELEEIFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVEQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDERSTYTVLGDPTEACLNVLLEKSGINRQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDGAKVISGLELSEMTDSQLKKELSGEAVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKTLSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLIGCPFIMIGLDEVRKLFSSRKNKR
>NZ_ANDC01000023.1|WP_000065320.1|58004_59108_-|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEISLEFEKQFAAMVFTIPNINYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGTGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFLGAYHDNSRETK
>NZ_ANDC01000023.1|WP_001875996.1|57302_57884_+|CatB-related-O-acetyltransferase
MRTDMSTGASYPKYRFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL
>NZ_ANDC01000023.1|WP_001056394.1|55924_56536_-|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN
>NZ_ANDC01000023.1|WP_000590706.1|70531_71197_-|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_ANDC01000023.1|WP_000122197.1|71183_71525_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGSITLLTVTEKQFARMVYLHGEHNMSVANSDSRLVFLGDSYDQD
>NZ_ANDC01000023.1|WP_000929490.1|71521_72391_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLESFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLILSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_ANDC01000023.1|WP_001040103.1|72392_76526_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATMQEEKYYHEKFPTIYHLRKELADKKEKADLRLVYLALAHIIKFRGHFLIEDDRFDVRNTDIQKQYQAFLEIFDTTFENNHLLSQNVDVEAILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSVAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHHEDLKHLKQFVKASLPENYREVFADSSKDGYAGYIEGKTNQEAFYKYLLKLLTKQEGSEYFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELRAIIRRQSEYYPFLKENQDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRFLAEGFKDFQFLNRKQKETIFNSLFKEKRKVTEKDIISFLNKVDGYEGIAIKGIEKQFNASLSTYHDLKKILGKDFLDNTDNELILEDIVQTLTLFEDREMIKKCLDIYKDFFTESQLKKLYRRHYTGWGRLSAKLINGIRNKENQKTILDYLIDDGSANRNFMQLINDDDLSFKPIIDKARTGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTAKGLSRSRQRLTTLRESLANLKSNILEEKKPKYVKDQVENHHLSDDRLFLYYLQNGRDMYTKKALDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSIEIVKARKMFWKNLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNEVDNGKKICKVKIVTLKSNLVSNFRKEFGFYKIREVNDYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGMYRQKKLSKIVHEDKEEKYSEATRKMFFYSNLMNMFKRVVRLADGSIVVRPVIETGRYMRKTAWDKKKHFATVRKVLSYPQNNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRDDKLMILPKYSLFELENGRRRLLASAGELQKGNELALPTQFMKFLYLASRYNESKGKPEEIEKKQEFVNQHVSYFDDILQLINDFSKRVILADANLEKINKLYQDNKENIPVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>NZ_ANDC01000023.1|WP_000653350.1|76914_77571_-|TIGR01906-family-membrane-protein
MKDKLLIVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_ANDC01000023.1|WP_000323544.1|77560_78331_-|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_ANDC01000023.1|WP_000523795.1|78331_79069_-|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_ANDC01000023.1|WP_000914658.1|79072_80203_-|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELIRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_ANDC01000023.1|WP_001241816.1|80294_80675_-|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_ANDC01000023.1|WP_000159235.1|80699_81071_-|YbgA-family-protein
MTKEAKLLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_ANDC01000023_1	1.5\|69838\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69838-69867	30	MK448742	Streptococcus phage Javan37, complete genome	28973-29002	0	1.0
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448749	Streptococcus phage Javan39, complete genome	20005-20034	0	1.0
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MH853356	Streptococcus phage LF2, partial genome	43016-43045	0	1.0
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448956	Streptococcus phage Javan48, complete genome	33900-33929	1	0.967
NZ_ANDC01000023_1	1.5\|69838\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69838-69867	30	MK448956	Streptococcus phage Javan48, complete genome	32279-32308	1	0.967
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MK448742	Streptococcus phage Javan37, complete genome	29903-29932	1	0.967
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MK448851	Streptococcus phage Javan14, complete genome	33850-33879	1	0.967
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	JX409894	Streptococcus phage LYGO9, complete genome	13214-13243	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448971	Streptococcus phage Javan52, complete genome	35890-35919	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448829	Streptococcus phage Javan7, complete genome	30583-30612	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448736	Streptococcus phage Javan35, complete genome	31054-31083	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448781	Streptococcus phage Javan5, complete genome	33076-33105	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448749	Streptococcus phage Javan39, complete genome	35482-35511	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MH853355	Streptococcus phage LF1, complete genome	21440-21469	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	JX409895	Streptococcus phage JX01, complete genome	25061-25090	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448938	Streptococcus phage Javan44, complete genome	31055-31084	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MH853356	Streptococcus phage LF2, partial genome	27496-27525	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448911	Streptococcus phage Javan34, complete genome	31054-31083	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448837	Streptococcus phage Javan10, complete genome	29112-29141	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MH853358	Streptococcus phage LF4, complete genome	21440-21469	2	0.933
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448916	Streptococcus phage Javan36, complete genome	31054-31083	2	0.933
NZ_ANDC01000023_1	1.5\|69838\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69838-69867	30	MK448796	Streptococcus phage Javan53, complete genome	37775-37804	2	0.933
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	MK448924	Streptococcus phage Javan384, complete genome	7947-7976	2	0.933
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MK448956	Streptococcus phage Javan48, complete genome	33209-33238	2	0.933
NZ_ANDC01000023_1	1.10\|70168\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70168-70197	30	JX409894	Streptococcus phage LYGO9, complete genome	31844-31873	2	0.933
NZ_ANDC01000023_1	1.10\|70168\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70168-70197	30	JX409895	Streptococcus phage JX01, complete genome	662-691	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448796	Streptococcus phage Javan53, complete genome	36041-36070	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448971	Streptococcus phage Javan52, complete genome	32226-32255	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448829	Streptococcus phage Javan7, complete genome	26921-26950	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448956	Streptococcus phage Javan48, complete genome	30545-30574	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MH853355	Streptococcus phage LF1, complete genome	17778-17807	2	0.933
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MH853358	Streptococcus phage LF4, complete genome	17778-17807	2	0.933
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	AJ609634	Bacteriophage EJ-1 proviral DNA, complete genome	10413-10442	3	0.9
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	NC_005294	Streptococcus prophage EJ-1, complete genome	10413-10442	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448859	Streptococcus phage Javan170, complete genome	20220-20249	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448690	Streptococcus phage Javan169, complete genome	20578-20607	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448850	Streptococcus phage Javan132, complete genome	19807-19836	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448676	Streptococcus phage Javan131, complete genome	22730-22759	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448688	Streptococcus phage Javan161, complete genome	20173-20202	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448973	Streptococcus phage Javan522, complete genome	19671-19700	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448955	Streptococcus phage Javan478, complete genome	21048-21077	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448778	Streptococcus phage Javan493, complete genome	19213-19242	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448962	Streptococcus phage Javan496, complete genome	9204-9233	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448975	Streptococcus phage Javan526, complete genome	19995-20024	3	0.9
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448782	Streptococcus phage Javan501, complete genome	22353-22382	3	0.9
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448837	Streptococcus phage Javan10, complete genome	25450-25479	3	0.9
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448742	Streptococcus phage Javan37, complete genome	27241-27270	3	0.9
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448851	Streptococcus phage Javan14, complete genome	31180-31209	3	0.9
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	KC465899	Pelagibacter phage HTVC008M, complete genome	125202-125231	4	0.867
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	JX409894	Streptococcus phage LYGO9, complete genome	28656-28685	4	0.867
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	MK448675	Streptococcus phage Javan129, complete genome	20470-20499	4	0.867
NZ_ANDC01000023_1	1.11\|70234\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70234-70263	30	JX409895	Streptococcus phage JX01, complete genome	40503-40532	4	0.867
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MK448749	Streptococcus phage Javan39, complete genome	31818-31847	4	0.867
NZ_ANDC01000023_1	1.12\|70300\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70300-70329	30	MH853356	Streptococcus phage LF2, partial genome	31159-31188	4	0.867
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MN693096	Marine virus AFVG_25M80, complete genome	24962-24991	5	0.833
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP035396	Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence	5260-5289	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP032856	Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence	45542-45571	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_MG557999	Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence	51740-51769	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_MF497781	Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence	51740-51769	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MT074138	Bacteroides phage DAC17, complete genome	95749-95778	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MT074136	Bacteroides phage DAC15, complete genome	96339-96368	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP046030	Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence	15565-15594	6	0.8
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	AP014166	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, * SEQUENCING IN PROGRESS *	5438-5467	6	0.8
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	AP014287	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S24-C25, * SEQUENCING IN PROGRESS *	29553-29582	6	0.8
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448932	Streptococcus phage Javan42, complete genome	30325-30354	7	0.767
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448742	Streptococcus phage Javan37, complete genome	30594-30623	7	0.767
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448669	Streptococcus phage Javan11, complete genome	30754-30783	7	0.767
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448708	Streptococcus phage Javan23, complete genome	33082-33111	7	0.767
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK448897	Streptococcus phage Javan28, complete genome	33082-33111	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_KR091915	Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence	42923-42952	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP025915	Escherichia coli strain 203740 plasmid p203740_35, complete sequence	8594-8623	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_LS999564	Escherichia coli isolate EC-TO143 plasmid 5, complete sequence	682-711	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_LN824136	Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671	16675-16704	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP054370	Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence	19258-19287	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP006640	Escherichia coli PCN061 plasmid PCN061p4, complete sequence	5957-5986	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP029801	Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence	7884-7913	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP015505	Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence	27842-27871	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP026060	Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence	16877-16906	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP024853	Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence	326-355	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_LT985287	Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence	31253-31282	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP028999	Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence	14730-14759	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP027258	Escherichia coli strain EC11 plasmid unnamed3, complete sequence	21718-21747	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP019200	Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence	31777-31806	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP023823	Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence	16675-16704	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP026025	Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence	33042-33071	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP018988	Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence	682-711	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_MK033500	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence	7491-7520	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_MK033501	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence	55790-55819	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_MK033499	Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence	107898-107927	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MN693256	Marine virus AFVG_25M339, complete genome	27548-27577	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_LR215001	Mycoplasma conjunctivae strain NCTC10147 plasmid 5	7233-7262	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MN855807	Siphoviridae sp. isolate 122, partial genome	13518-13547	7	0.767
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	FJ429185	Lactococcus phage P087, complete genome	18714-18743	7	0.767
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	MT778840	Rhizobium phage P11VFA, complete genome	28085-28114	7	0.767
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	63260-63289	7	0.767
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	MF417890	Uncultured Caudovirales phage clone 7F_15, partial genome	31755-31784	7	0.767
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	MF417953	Uncultured Caudovirales phage clone 7S_15, partial genome	5050-5079	7	0.767
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	GU557055	Puniceispirillum phage HMO-2011, complete genome	33660-33689	7	0.767
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	NZ_CP044019	Acinetobacter indicus strain HY20 plasmid pAI01, complete sequence	64701-64730	7	0.767
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	MN855940	Myoviridae sp. isolate 64, complete genome	2455-2484	7	0.767
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	CAJCJZ010000002	Enterococcus phage vB_EfaS_140 genome assembly, contig: phage140-genome, whole genome shotgun sequence	37602-37631	7	0.767
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	MT119360	Enterococcus phage nattely, complete genome	46883-46912	7	0.767
NZ_ANDC01000023_1	1.7\|69970\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69970-69999	30	NZ_CP028120	Escherichia coli O43 str. RM10042 plasmid pRM10042-1, complete sequence	45471-45500	7	0.767
NZ_ANDC01000023_1	1.7\|69970\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69970-69999	30	NZ_CP033633	Escherichia coli isolate ECCNB12-2 plasmid pTB-nb2, complete sequence	135584-135613	7	0.767
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NC_012530	Lactobacillus phage Lb338-1, complete genome	12604-12633	7	0.767
NZ_ANDC01000023_1	1.13\|70366\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70366-70395	30	NC_004534	Corynebacterium glutamicum plasmid pCG2, complete sequence	2537-2566	7	0.767
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250021	Prevotella phage Lak-B2, complete genome	147280-147309	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250024	Prevotella phage Lak-B5, complete genome	142029-142058	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250028	Prevotella phage Lak-B9, complete genome	146163-146192	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250023	Prevotella phage Lak-B4, complete genome	147183-147212	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250025	Prevotella phage Lak-B6, complete genome	145222-145251	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250022	Prevotella phage Lak-B3, complete genome	145237-145266	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250027	Prevotella phage Lak-B8, complete genome	147394-147423	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250026	Prevotella phage Lak-B7, complete genome	147393-147422	8	0.733
NZ_ANDC01000023_1	1.1\|69574\|30\|NZ_ANDC01000023\|CRT	69574-69603	30	MK250020	Prevotella phage Lak-B1, complete genome	146143-146172	8	0.733
NZ_ANDC01000023_1	1.2\|69640\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69640-69669	30	NZ_CP050094	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence	273778-273807	8	0.733
NZ_ANDC01000023_1	1.2\|69640\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69640-69669	30	NC_008379	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence	256698-256727	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	70939-70968	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP012103	Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence	20110-20139	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_LR214953	Mycoplasma neurolyticum strain NCTC10166 plasmid 3	5510-5539	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP009352	Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence	2297-2326	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NZ_CP051681	Cohnella sp. MFER-1 plasmid unnamed1	74376-74405	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NC_004952	Francisella novicida plasmid pFNL10, complete sequence	110-139	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NC_002109	Francisella tularensis plasmid pOM1, complete sequence	110-139	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	LC494302	Escherichia phage SP27 DNA, complete genome	245480-245509	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	230963-230992	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	NC_027364	Escherichia phage PBECO 4, complete genome	39408-39437	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MH383160	Escherichia phage UB, complete genome	99995-100024	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MK327931	Escherichia phage vB_EcoM_G17, complete genome	256257-256286	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MN871445	UNVERIFIED: Serratia phage KpHz_2, complete genome	75797-75826	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MK448636	Streptococcus satellite phage Javan749, complete genome	10387-10416	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MN871444	UNVERIFIED: Serratia phage KpGz_1, complete genome	13324-13353	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	MN693101	Marine virus AFVG_25M559, complete genome	25633-25662	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	KT725776	Bacillus phage vB_BceS-MY192, partial genome	2349-2378	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	187103-187132	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	KM507819	Escherichia phage 121Q, complete genome	246579-246608	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	NC_008201	Mannheimia phage phiMHaA1, complete genome	22041-22070	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	DQ426905	Bacteriophage phi-MhaA1-BAA410, complete genome	22116-22145	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	KP137432	Mannheimia phage vB_MhM_535AP1, complete genome	22081-22110	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	JN255163	Mannheimia phage vB_MhM_1152AP, complete genome	22277-22306	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	KP137438	Mannheimia phage vB_MhM_2256AP1, complete genome	22442-22471	8	0.733
NZ_ANDC01000023_1	1.4\|69772\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69772-69801	30	DQ426904	Bacteriophage phi-MhaA1-PHL101, complete genome	22041-22070	8	0.733
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	MK448665	Streptococcus phage Javan1, complete genome	31865-31894	8	0.733
NZ_ANDC01000023_1	1.6\|69904\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69904-69933	30	NZ_CP053834	Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence	102759-102788	8	0.733
NZ_ANDC01000023_1	1.7\|69970\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	69970-69999	30	NC_014502	Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence	95768-95797	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MN871480	UNVERIFIED: Pseudomonas phage PaSz-1_45_270k, complete genome	229744-229773	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MT001829	Salmonella phage SE_PL, complete genome	257363-257392	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	DI373487	KR 1020130142837-A/1: Bacteriophage of Pseudomonas aeruginosa and uses thereof	253719-253748	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MK773491	Salmonella phage 7t3, complete genome	91373-91402	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MN871489	UNVERIFIED: Pseudomonas phage PaZh_1, complete genome	261622-261651	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NC_042081	Pseudomonas phage SL2, complete genome	232282-232311	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	MK268344	Salmonella phage Munch, complete genome	28685-28714	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NC_042060	Pseudomonas phage PA7, partial genome	253719-253748	8	0.733
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NC_004629	Pseudomonas phage phiKZ, complete genome	52347-52376	8	0.733
NZ_ANDC01000023_1	1.3\|69706\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder	69706-69735	30	HQ683709	Planktothrix phage PaV-LD, complete genome	72162-72191	9	0.7
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NZ_CP046044	Acinetobacter towneri strain 19110F47 plasmid p19110F47-2, complete sequence	79842-79871	9	0.7
NZ_ANDC01000023_1	1.9\|70102\|30\|NZ_ANDC01000023\|CRT,CRISPRCasFinder,PILER-CR	70102-70131	30	NZ_CP048015	Acinetobacter towneri strain 205 plasmid pAT205, complete sequence	1512-1541	9	0.7

1. spacer 1.5|69838|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ctagctttatttatcccgttgcggatgttt	CRISPR spacer
ctagctttatttatcccgttgcggatgttt	Protospacer
******************************

2. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

atagtcatccatcataacgactggtgtgat	CRISPR spacer
atagtcatccatcataacgactggtgtgat	Protospacer
******************************

3. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

atagtcatccatcataacgactggtgtgat	CRISPR spacer
atagtcatccatcataacgactggtgtgat	Protospacer
******************************

4. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 1, identity: 0.967

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaacaaatgattttgtaccatc	Protospacer
****** ***********************

5. spacer 1.5|69838|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 1, identity: 0.967

ctagctttatttatcccgttgcggatgttt	CRISPR spacer
ctaactttatttatcccgttgcggatgttt	Protospacer
***.**************************

6. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 1, identity: 0.967

agctctaaatcaacatatccatcaacttca	CRISPR spacer
agttctaaatcaacatatccatcaacttca	Protospacer
**.***************************

7. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.967

agctctaaatcaacatatccatcaacttca	CRISPR spacer
agttctaaatcaacatatccatcaacttca	Protospacer
**.***************************

8. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

9. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

10. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

11. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

12. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

13. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

14. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

15. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

16. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

17. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

18. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

19. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

20. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

21. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 2, identity: 0.933

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtcccaaaaaatgattttgtaccatc	Protospacer
****** **** ******************

22. spacer 1.5|69838|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 2, identity: 0.933

ctagctttatttatcccgttgcggatgttt	CRISPR spacer
ctagctttatttattccgttgcggatgttc	Protospacer
**************.**************.

23. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448924 (Streptococcus phage Javan384, complete genome) position: , mismatch: 2, identity: 0.933

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
gaagtaaaagatatttatgcagaagttatc	Protospacer
************************** **.

24. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 2, identity: 0.933

agctctaaatcaacatatccatcaacttca	CRISPR spacer
agttctaaatcaacatatccatcgacttca	Protospacer
**.********************.******

25. spacer 1.10|70168|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 2, identity: 0.933

cctacacactcgtctcacgtactgttgaca	CRISPR spacer
cctacacactcgtcgcacgtactgctgaca	Protospacer
************** *********.*****

26. spacer 1.10|70168|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 2, identity: 0.933

cctacacactcgtctcacgtactgttgaca	CRISPR spacer
cctacacactcgtcgcacgtactgctgaca	Protospacer
************** *********.*****

27. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttgtaaaatctccagc	Protospacer
*.****.***********************

28. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
gaaattcaaactgcttataaaatctccaac	Protospacer
****************.***********.*

29. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448829 (Streptococcus phage Javan7, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttgtaaaatctccagc	Protospacer
*.****.***********************

30. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
gaaattcaaactgcttataaaatctccaac	Protospacer
****************.***********.*

31. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MH853355 (Streptococcus phage LF1, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttgtaaaatctccagc	Protospacer
*.****.***********************

32. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MH853358 (Streptococcus phage LF4, complete genome) position: , mismatch: 2, identity: 0.933

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttgtaaaatctccagc	Protospacer
*.****.***********************

33. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to AJ609634 (Bacteriophage EJ-1 proviral DNA, complete genome) position: , mismatch: 3, identity: 0.9

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
gaagtgaaagatatttatgcagaagttatc	Protospacer
*****.******************** **.

34. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_005294 (Streptococcus prophage EJ-1, complete genome) position: , mismatch: 3, identity: 0.9

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
gaagtgaaagatatttatgcagaagttatc	Protospacer
*****.******************** **.

35. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
gtagtcatccatcataataactggtgtgat	Protospacer
.****************..***********

36. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
gtagtcatccatcataataactggtgtgat	Protospacer
.****************..***********

37. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
gtagtcatccatcataataactggtgtgat	Protospacer
.****************..***********

38. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
gtagtcatccatcataataactggtgtgat	Protospacer
.****************..***********

39. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
gtagtcatccatcataataactggtgtgat	Protospacer
.****************..***********

40. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

41. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

42. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

43. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

44. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

45. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.9

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataacaactggtgtgat	Protospacer
* *.**************.***********

46. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 3, identity: 0.9

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttataaaatctccagc	Protospacer
*.****.*********.*************

47. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 3, identity: 0.9

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttataaaatctccagc	Protospacer
*.****.*********.*************

48. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 3, identity: 0.9

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
gaaattcaaattgcttataaaatctccaac	Protospacer
**********.*****.***********.*

49. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to KC465899 (Pelagibacter phage HTVC008M, complete genome) position: , mismatch: 4, identity: 0.867

aaatgttcttttttaaaatctttcatgttc-	CRISPR spacer
aaatctacttttttaaaatcttt-atattca	Protospacer
**** * **************** **.***

50. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 4, identity: 0.867

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataataactggtgtgat	Protospacer
* *.*************..***********

51. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 4, identity: 0.867

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataataactggtgtgat	Protospacer
* *.*************..***********

52. spacer 1.11|70234|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 4, identity: 0.867

atagtcatccatcataacgactggtgtgat	CRISPR spacer
aaaatcatccatcataataactggtgtgat	Protospacer
* *.*************..***********

53. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 4, identity: 0.867

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttataaaatctccaac	Protospacer
*.****.*********.***********.*

54. spacer 1.12|70300|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 4, identity: 0.867

gaaattcaaactgcttgtaaaatctccagc	CRISPR spacer
ggaatttaaactgcttataaaatctccaac	Protospacer
*.****.*********.***********.*

55. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MN693096 (Marine virus AFVG_25M80, complete genome) position: , mismatch: 5, identity: 0.833

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
acaagaaacaacaaatgattttgtaccaac	Protospacer
*. ** * ******************** *

56. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP035396 (Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ccaagttcttttttaaaatcattcatgtgt	Protospacer
  * **************** ******* .

57. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP032856 (Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ccaagttcttttttaaaatcattcatgtgt	Protospacer
  * **************** ******* .

58. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_MG557999 (Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttaaaatctttcaccccc	Protospacer
.** *********************. ..*

59. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_MF497781 (Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttaaaatctttcaccccc	Protospacer
.** *********************. ..*

60. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MT074138 (Bacteroides phage DAC17, complete genome) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
atatgttcttttttaaagtcttgcattgtt	Protospacer
* ***************.**** ***  *.

61. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MT074136 (Bacteroides phage DAC15, complete genome) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
atatgttcttttttaaagtcttgcattgtt	Protospacer
* ***************.**** ***  *.

62. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP046030 (Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

---aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gctaaa---tcttttctaaaatctttcatggtg	Protospacer
   ***   ******.************** *

63. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to AP014166 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatcttcttttttagaatctttaacttta	Protospacer
**** **********.******* *. **

64. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to AP014287 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S24-C25, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

agctctaaatcaacatatccatcaacttca	CRISPR spacer
accttgaaatcaacatctccatcaactttg	Protospacer
* **. ********** ***********..

65. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448932 (Streptococcus phage Javan42, complete genome) position: , mismatch: 7, identity: 0.767

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
ccaacttccagaaaatgattttgtaccatc	Protospacer
 . * * ***. ******************

66. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 7, identity: 0.767

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
ccaacttccagaaaatgattttgtaccatc	Protospacer
 . * * ***. ******************

67. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448669 (Streptococcus phage Javan11, complete genome) position: , mismatch: 7, identity: 0.767

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
ccaacttccagaaaatgattttgtaccatc	Protospacer
 . * * ***. ******************

68. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448708 (Streptococcus phage Javan23, complete genome) position: , mismatch: 7, identity: 0.767

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
ccaacttccagaaaatgattttgtaccatc	Protospacer
 . * * ***. ******************

69. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK448897 (Streptococcus phage Javan28, complete genome) position: , mismatch: 7, identity: 0.767

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
ccaacttccagaaaatgattttgtaccatc	Protospacer
 . * * ***. ******************

70. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_KR091915 (Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

71. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP025915 (Escherichia coli strain 203740 plasmid p203740_35, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

72. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_LS999564 (Escherichia coli isolate EC-TO143 plasmid 5, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

73. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_LN824136 (Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

74. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP054370 (Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

75. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP006640 (Escherichia coli PCN061 plasmid PCN061p4, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

76. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP029801 (Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

77. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP015505 (Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

78. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP026060 (Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

79. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP024853 (Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

80. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_LT985287 (Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

81. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP028999 (Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

82. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP027258 (Escherichia coli strain EC11 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

83. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP019200 (Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

84. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP023823 (Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

85. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP026025 (Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

86. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP018988 (Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

87. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_MK033500 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

88. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_MK033501 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

89. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_MK033499 (Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gaaggttcttttttgaaatctttcaccccc	Protospacer
.** **********.**********. ..*

90. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MN693256 (Marine virus AFVG_25M339, complete genome) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
tcttcttctttttttaaatctttcatgctg	Protospacer
   * ********* ************.*

91. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_LR215001 (Mycoplasma conjunctivae strain NCTC10147 plasmid 5) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatgctcttttttaaaatttttatcttcc	Protospacer
*****.*************.***  . *.*

92. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MN855807 (Siphoviridae sp. isolate 122, partial genome) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
tagtaatcttttttaatatctttcatggtg	Protospacer
 *.*. ********** ********** *

93. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to FJ429185 (Lactococcus phage P087, complete genome) position: , mismatch: 7, identity: 0.767

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
tagtaatcttttttaatatctttcatggtg	Protospacer
 *.*. ********** ********** *

94. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 7, identity: 0.767

tacggtggacaagctaacccacaagaaact	CRISPR spacer
caacgtggacaagctcacccacaagaacga	Protospacer
.*  *********** ***********

95. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 7, identity: 0.767

tacggtggacaagctaacccacaagaaact	CRISPR spacer
caacgtggacaagctcacccacaagaacga	Protospacer
.*  *********** ***********

96. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MF417890 (Uncultured Caudovirales phage clone 7F_15, partial genome) position: , mismatch: 7, identity: 0.767

tacggtggacaagctaacccacaagaaact	CRISPR spacer
caaagtggacaagctaagccacaacaagca	Protospacer
.* .************* ****** **.*

97. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MF417953 (Uncultured Caudovirales phage clone 7S_15, partial genome) position: , mismatch: 7, identity: 0.767

tacggtggacaagctaacccacaagaaact	CRISPR spacer
caaagtggacaagctaagccacaacaagca	Protospacer
.* .************* ****** **.*

98. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to GU557055 (Puniceispirillum phage HMO-2011, complete genome) position: , mismatch: 7, identity: 0.767

tacggtggacaagctaacccacaagaaact	CRISPR spacer
tacggtggacaatctaacccattggtaaga	Protospacer
************ ********. .* **

99. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP044019 (Acinetobacter indicus strain HY20 plasmid pAI01, complete sequence) position: , mismatch: 7, identity: 0.767

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
caggtaaatgatatttatgcacaagtagct	Protospacer
 *.***** ************ ****...*

100. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MN855940 (Myoviridae sp. isolate 64, complete genome) position: , mismatch: 7, identity: 0.767

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
gaagtaaaagagatttatggagagtgggct	Protospacer
*********** ******* ***.  *..*

101. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to CAJCJZ010000002 (Enterococcus phage vB_EfaS_140 genome assembly, contig: phage140-genome, whole genome shotgun sequence) position: , mismatch: 7, identity: 0.767

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
aaactaaaagatatttatgcacaattagtc	Protospacer
.** ***************** ** *..*.

102. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 7, identity: 0.767

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
aaactaaaagatatttatgcacaattagta	Protospacer
.** ***************** ** *..*

103. spacer 1.7|69970|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP028120 (Escherichia coli O43 str. RM10042 plasmid pRM10042-1, complete sequence) position: , mismatch: 7, identity: 0.767

tccgcaagatgaaacagatatctctttaaa	CRISPR spacer
tccgcaatatgatacagatatctctgcccg	Protospacer
******* **** ************ .  .

104. spacer 1.7|69970|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP033633 (Escherichia coli isolate ECCNB12-2 plasmid pTB-nb2, complete sequence) position: , mismatch: 7, identity: 0.767

tccgcaagatgaaacagatatctctttaaa	CRISPR spacer
tccgcaatatgatacagatatctctgcccg	Protospacer
******* **** ************ .  .

105. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_012530 (Lactobacillus phage Lb338-1, complete genome) position: , mismatch: 7, identity: 0.767

agctctaaatcaacatatccatcaacttca	CRISPR spacer
gttcctaaaacaacatatccatcaacctga	Protospacer
. ..***** ****************.* *

106. spacer 1.13|70366|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_004534 (Corynebacterium glutamicum plasmid pCG2, complete sequence) position: , mismatch: 7, identity: 0.767

catacatgtatgtaagtggtaagagttttt	CRISPR spacer
catacatgtatgtaagtggtaaaacaccag	Protospacer
**********************.*  ..

107. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250021 (Prevotella phage Lak-B2, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

108. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

109. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250028 (Prevotella phage Lak-B9, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

110. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

111. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250025 (Prevotella phage Lak-B6, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

112. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250022 (Prevotella phage Lak-B3, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

113. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

114. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250026 (Prevotella phage Lak-B7, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

115. spacer 1.1|69574|30|NZ_ANDC01000023|CRT matches to MK250020 (Prevotella phage Lak-B1, complete genome) position: , mismatch: 8, identity: 0.733

atcagtaccaacaaatgattttgtaccatc	CRISPR spacer
atcagtaacaacaaataattttggagacaa	Protospacer
******* ********.****** *

116. spacer 1.2|69640|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP050094 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence) position: , mismatch: 8, identity: 0.733

tcagcattcggcattgatattttcccctct	CRISPR spacer
cgcgccttcggcattgatattttcatagct	Protospacer
.  ** ****************** .  **

117. spacer 1.2|69640|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NC_008379 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence) position: , mismatch: 8, identity: 0.733

tcagcattcggcattgatattttcccctct	CRISPR spacer
cgcgccttcggcattgatattttcatagct	Protospacer
.  ** ****************** .  **

118. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatgttcttttttaaattctactagtata	Protospacer
***************** *** ..*   *

119. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP012103 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
cgacctcattttttaaaatctttgatgttt	Protospacer
 .*. *. *************** *****.

120. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_LR214953 (Mycoplasma neurolyticum strain NCTC10166 plasmid 3) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatgttgttttttaaaatttttatcaatt	Protospacer
******* ***********.***  .. *.

121. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP009352 (Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ctattctcttttttaaaatcgttcatgcaa	Protospacer
  ** .************** ******.

122. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NZ_CP051681 (Cohnella sp. MFER-1 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
accgtttctttttcaaaatcgttcatgtga	Protospacer
*    ********.****** *******

123. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NC_004952 (Francisella novicida plasmid pFNL10, complete sequence) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ctattctcttttttaaaatcgttcatgcaa	Protospacer
  ** .************** ******.

124. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NC_002109 (Francisella tularensis plasmid pOM1, complete sequence) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ctattctcttttttaaaatcgttcatgcaa	Protospacer
  ** .************** ******.

125. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

126. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

127. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

128. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

129. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

130. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MN871445 (UNVERIFIED: Serratia phage KpHz_2, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatgttctttttttaaatctaagaggaat	Protospacer
************** ******   * *  .

131. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MK448636 (Streptococcus satellite phage Javan749, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
tagatttcttttttaaaatcttttataaac	Protospacer
 *.  ******************.**.  *

132. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MN871444 (UNVERIFIED: Serratia phage KpGz_1, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
aaatgttctttttttaaatctaagaggaat	Protospacer
************** ******   * *  .

133. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to MN693101 (Marine virus AFVG_25M559, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
caatgttcttttttaaattcttctactctt	Protospacer
 **************** ****..*. .*.

134. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to KT725776 (Bacillus phage vB_BceS-MY192, partial genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ccttgttcttttttaaaatcaatcatccac	Protospacer
   *****************  **** . *

135. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

136. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 8, identity: 0.733

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
ttctgttcttttttcaaagctttcatatga	Protospacer
   *********** *** *******.*

137. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_008201 (Mannheimia phage phiMHaA1, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

138. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to DQ426905 (Bacteriophage phi-MhaA1-BAA410, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

139. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to KP137432 (Mannheimia phage vB_MhM_535AP1, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

140. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to JN255163 (Mannheimia phage vB_MhM_1152AP, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

141. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to KP137438 (Mannheimia phage vB_MhM_2256AP1, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

142. spacer 1.4|69772|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to DQ426904 (Bacteriophage phi-MhaA1-PHL101, complete genome) position: , mismatch: 8, identity: 0.733

tacggtggacaagctaacccacaagaaact	CRISPR spacer
cacggtggacgagctaacccacgatggccc	Protospacer
.*********.***********.* .. *.

143. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK448665 (Streptococcus phage Javan1, complete genome) position: , mismatch: 8, identity: 0.733

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
gaagtaaaagttatttttgcagaacctgca	Protospacer
********** ***** ******* . ..

144. spacer 1.6|69904|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP053834 (Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence) position: , mismatch: 8, identity: 0.733

gaagtaaaagatatttatgcagaagtgatt	CRISPR spacer
tatacaaaagatattgatgcagaagttaaa	Protospacer
 * ..********** ********** *

145. spacer 1.7|69970|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_014502 (Gloeothece verrucosa PCC 7822 plasmid Cy782203, complete sequence) position: , mismatch: 8, identity: 0.733

tccgcaagatgaaacagatatctctttaaa	CRISPR spacer
gtttctcgatgaaaccgatatctttttaaa	Protospacer
 .. *  ******** *******.******

146. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MN871480 (UNVERIFIED: Pseudomonas phage PaSz-1_45_270k, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

147. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MT001829 (Salmonella phage SE_PL, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
gaatgtaaatcatcatatctatcaactttt	Protospacer
.. * ******* ******.********.

148. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to DI373487 (KR 1020130142837-A/1: Bacteriophage of Pseudomonas aeruginosa and uses thereof) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

149. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK773491 (Salmonella phage 7t3, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
gaatgtaaatcatcatatctatcaactttt	Protospacer
.. * ******* ******.********.

150. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MN871489 (UNVERIFIED: Pseudomonas phage PaZh_1, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

151. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_042081 (Pseudomonas phage SL2, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

152. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to MK268344 (Salmonella phage Munch, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
gaatgtaaatcatcatatctatcaactttt	Protospacer
.. * ******* ******.********.

153. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_042060 (Pseudomonas phage PA7, partial genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

154. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NC_004629 (Pseudomonas phage phiKZ, complete genome) position: , mismatch: 8, identity: 0.733

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttataagaaccaccatatccatcaacttca	Protospacer
   *  .**.** *****************

155. spacer 1.3|69706|30|NZ_ANDC01000023|CRT,CRISPRCasFinder matches to HQ683709 (Planktothrix phage PaV-LD, complete genome) position: , mismatch: 9, identity: 0.7

aaatgttcttttttaaaatctttcatgttc	CRISPR spacer
gccaattctttgttaaaatctgtcatgtgg	Protospacer
.   .****** ********* ******

156. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP046044 (Acinetobacter towneri strain 19110F47 plasmid p19110F47-2, complete sequence) position: , mismatch: 9, identity: 0.7

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttgctgaaatcaacatatccatgagcttct	Protospacer
   .. **************** *.****

157. spacer 1.9|70102|30|NZ_ANDC01000023|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP048015 (Acinetobacter towneri strain 205 plasmid pAT205, complete sequence) position: , mismatch: 9, identity: 0.7

agctctaaatcaacatatccatcaacttca	CRISPR spacer
ttgctgaaatcaacatatccatgagcttct	Protospacer
   .. **************** *.****

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_ANDC01000018

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

42737 : 54802

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000783419.1\|42737_44042_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	1.2e-11	34.2
WP_001045908.1\|44188_45088_-	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000166549.1\|45280_46828_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.7e-44	52.4
WP_000780022.1\|46847_47600_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000685109.1\|47622_48171_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.4e-25	35.6
WP_001291328.1\|48338_49361_-	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	1.1e-63	42.7
WP_000220676.1\|49388_50843_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_001042250.1\|51076_54802_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.9e-38	25.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_ANDC01000021

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

39686 : 46890

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000706188.1\|39686_40931_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.7e-87	41.3
WP_000217754.1\|40932_42216_+	insulinase family protein	A0A2K9V7S4	Bandra_megavirus	1.3e-21	33.3
WP_000976003.1\|42338_42881_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000181757.1\|42880_43720_+	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
WP_000510606.1\|43695_44538_+	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	2.5e-18	25.5
WP_000359358.1\|44530_45325_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000029066.1\|45540_46080_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	5.8e-21	42.2
WP_001042655.1\|46185_46890_+	transglycosylase SLT domain-containing protein	A0A2H4J6C5	uncultured_Caudovirales_phage	4.2e-27	56.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_ANDC01000015

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_ANDC01000015_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANDC01000015_1

196396-197693

Orphan

Consensus_repeat	Method
GTNGANGCGCTNGTNCTNGCTGANGT	CRT

20 spacers

The CRISPR arrays of NZ_ANDC01000015_1

>merge|NZ_ANDC01000015|1|196396-197693|CRT
GTGGAAGCGCTGGTACTTGCTGATGTCGATGCACTCGTTGAGACGCTGGTGCTGGCTGACGTCGTGGCACTCATTGAAGCGCTAGTGCTGGCTGACATTGACGCACTCGTTGAAGCGCTGGTGCTGGCTGACGTCGACGCACTCATTGAAGCGCTAGTGCTGGCTGACATCGAGGCACTTGTTGAAGAACTTGTGCTGGCTGACATTGACGCACTCGTTGAGGCGCTAGTGCTGGCTGACGTCGACGCACTCATGGAAGCACTTGTGCTGGCTGACGTCGAGGCACTCATTGAGGCGCTAGTGCTGGCTGATGTCGATGCACTGGTACTTGCACTTGTGGAAGAACTTGTACTTGCCGATGTTGAGGCGCTAGTACTTGCTGATGTGGAAGCACTCGTACTTGCACTTGTGGAAGCGCTGGTACTTGCTGATGTCGATGCACTCATTGAGGCGCTAGTACTTGCACTTGTGGAAGCACTGGTGCTGGCTGACGTCGATGCACTCATTGAGGCGCTAGTACTGGCTGACGTCGATGCACTGGTACTTGCACTTGTGGAAGCGCTCATACTTGCTGACGTGGATGCACTGATACTTGCACTTGTGGAGGCGCTCATACTTGCTGACGTGGATGCACTGGTACTTGCTGACGTGGATGCGCTCATACTTGCTGATGTGGATGCACTGGTACTTGCTGACGTGGAAGCGCTAGTACTTGTTGACGTCGAGGCACTGGTACTGGCACTTGTTGAAGCACTAGTACTTGCACTGGTTGAGGCGCTCATACTTGCACTTGTTGAAGCGCTAGTACTTGCACTTGTTGAGGCGCTCATACTTGCTGAGGTGGAAGCACTGGTTGAAGCACTGGTTGAAGCACTGGTTGAGGCGCTAGTGCTGGCTGACGTCGAGGCACTCATTGAAGCACTTGTGCTGGCTGACATCGACGCACTCATTGAGGCGCTAGTGCTGGCTGATGTGGAAGCACTGGTTGAAGCACTGGTTGAGGCGCTGGTGCTGGCTGACGTTGAGGCGCTAGTGCTGGCTGACGTTGAGGCACTCGTTGAGGCGCTGGTGCTGGCACTTGTGGAAGCGCTAGTACTTGCTGACGTGGATGCACTCGTACTTGCACTTGTTGAAGCACTCATACTTGCACTTGTTGAAGCACTTGTGCTGGCTGATGTCGAGGCACTCGTTGAGGTGCTGGTTGAAGCGCTGGTGCTGGCTGACGTCGACGCACTCATGGAAGCGCTGGTACTTGCTGATGTCGAGGCACTCATGGAAGCGCTGGTACTTGCTGACGT

>NZ_ANDC01000015|1|1|196396-197693|CRT
GTGGAAGCGCTGGTACTTGCTGATGT	CGATGCACTCGTTGAGACGCTGGTGCTGGCTGACGTCGTGGCACTC
ATTGAAGCGCTAGTGCTGGCTGACAT	TGACGCACTCGTTGAAGCGCTGGTGCTGGCTGACGTCGACGCACTC
ATTGAAGCGCTAGTGCTGGCTGACAT	CGAGGCACTTGTTGAAGAACTTGTGCTGGCTGACATTGACGCACTC
GTTGAGGCGCTAGTGCTGGCTGACGT	CGACGCACTCATGGAAGCACTTGTGCTGGCTGACGTCGAGGCACTC
ATTGAGGCGCTAGTGCTGGCTGATGT	CGATGCACTGGTACTTGCACTTGTGGAAGAACTTGTACTTGCCGAT
GTTGAGGCGCTAGTACTTGCTGATGT	GGAAGCACTCGTACTTGCACTT
GTGGAAGCGCTGGTACTTGCTGATGT	CGATGCACTCATTGAGGCGCTAGTACTTGCACTT
GTGGAAGCACTGGTGCTGGCTGACGT	CGATGCACTCATTGAGGCGCTAGTACTGGCTGACGTCGATGCACTGGTACTTGCACTT
GTGGAAGCGCTCATACTTGCTGACGT	GGATGCACTGATACTTGCACTTGTGGAGGCGCTCATACTTGCTGAC
GTGGATGCACTGGTACTTGCTGACGT	GGATGCGCTCATACTTGCTGAT
GTGGATGCACTGGTACTTGCTGACGT	GGAAGCGCTAGTACTTGTTGAC
GTCGAGGCACTGGTACTGGCACTTGT	TGAAGCACTAGTACTTGCACTG
GTTGAGGCGCTCATACTTGCACTTGT	TGAAGCGCTAGTACTTGCACTT
GTTGAGGCGCTCATACTTGCTGAGGT	GGAAGCACTGGTTGAAGCACTGGTTGAAGCACTG
GTTGAGGCGCTAGTGCTGGCTGACGT	CGAGGCACTCATTGAAGCACTTGTGCTGGCTGACATCGACGCACTC
ATTGAGGCGCTAGTGCTGGCTGATGT	GGAAGCACTGGTTGAAGCACTGGTTGAGGCGCTGGTGCTGGCTGAC
GTTGAGGCGCTAGTGCTGGCTGACGT	TGAGGCACTCGTTGAGGCGCTGGTGCTGGCACTT
GTGGAAGCGCTAGTACTTGCTGACGT	GGATGCACTCGTACTTGCACTTGTTGAAGCACTCATACTTGCACTT
GTTGAAGCACTTGTGCTGGCTGATGT	CGAGGCACTCGTTGAGGTGCTG
GTTGAAGCGCTGGTGCTGGCTGACGT	CGACGCACTCATGGAAGCGCTGGTACTTGCTGATGTCGAGGCACTC
ATGGAAGCGCTGGTACTTGCTGACGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANDC01000015.1\|WP_000795050.1\|191262_192447_-\|glycosyl-transferase-family-8	unknown	unknown	gnl\|CDD\|133037
NZ_ANDC01000015.1\|WP_000104405.1\|183685_184678_-\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_ANDC01000015.1\|WP_000502594.1\|208287_208446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000015.1\|WP_000751408.1\|193674_194880_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|133037
NZ_ANDC01000015.1\|WP_000681005.1\|204773_206957_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|270337
NZ_ANDC01000015.1\|WP_001865283.1\|192436_193678_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|133037
NZ_ANDC01000015.1\|WP_075316616.1\|190394_191282_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_ANDC01000015.1\|WP_000772257.1\|187784_189014_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_ANDC01000015.1\|WP_000244039.1\|210151_211393_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_ANDC01000015.1\|WP_000656279.1\|207845_208196_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000015.1\|WP_000818887.1\|206956_207697_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_ANDC01000015.1\|WP_001263852.1\|189137_190334_-\|SP_1767-family-glycosyltransferase	unknown	unknown	gnl\|CDD\|163440
NZ_ANDC01000015.1\|WP_000863865.1\|209845_209974_-\|DUF4044-domain-containing-protein	unknown	unknown	gnl\|CDD\|338651
NZ_ANDC01000015.1\|WP_000571941.1\|200025_201522_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|285470
NZ_ANDC01000015.1\|WP_001263776.1\|194888_195896_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|236626
NZ_ANDC01000015.1\|WP_000468351.1\|186240_187785_-\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598
NZ_ANDC01000015.1\|WP_000567072.1\|201618_203610_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_ANDC01000015.1\|WP_000061665.1\|208471_209785_-\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_ANDC01000015.1\|WP_075316641.1\|184674_186213_-\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_ANDC01000015.1\|WP_001042316.1\|203670_204591_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806

Protein	Function_ID	Function_description	E-value
NZ_ANDC01000015.1\|WP_000795050.1\|191262_192447_-\|glycosyl-transferase-family-8	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.05657e-73
NZ_ANDC01000015.1\|WP_000104405.1\|183685_184678_-\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	7.04012e-61
NZ_ANDC01000015.1\|WP_000751408.1\|193674_194880_-\|glycosyl-transferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.10249e-70
NZ_ANDC01000015.1\|WP_000681005.1\|204773_206957_+\|ABC-transporter-permease-subunit	gnl\|CDD\|270337	cd13619, PBP2_GlnP, Glutamine-binding domain of ABC transporter, a member of the type 2 periplasmic binding fold protein superfamily. Periplasmic glutamine binding domain GlnP serves as an initial receptor in the ABC transport of glutamine in eubacteria. GlnP belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.85761e-106
NZ_ANDC01000015.1\|WP_001865283.1\|192436_193678_-\|glycosyl-transferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	4.60076e-75
NZ_ANDC01000015.1\|WP_075316616.1\|190394_191282_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	4.6233e-33
NZ_ANDC01000015.1\|WP_000772257.1\|187784_189014_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	1.15376e-161
NZ_ANDC01000015.1\|WP_000244039.1\|210151_211393_+\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_ANDC01000015.1\|WP_000818887.1\|206956_207697_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.4733e-157
NZ_ANDC01000015.1\|WP_001263852.1\|189137_190334_-\|SP_1767-family-glycosyltransferase	gnl\|CDD\|163440	TIGR03728, glyco_access_1, glycosyltransferase, SP_1767 family. Members of this protein family are putative glycosyltransferases. Some members are found close to genes for the accessory secretory (SecA2) system, and are suggested by Partial Phylogenetic Profiling to correlate with SecA2 systems. Glycosylation, therefore, may occur in the cytosol prior to secretion.	9.90538e-161
NZ_ANDC01000015.1\|WP_000863865.1\|209845_209974_-\|DUF4044-domain-containing-protein	gnl\|CDD\|338651	pfam13253, DUF4044, Protein of unknown function (DUF4044). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 56 amino acids in length. There is a single completely conserved residue M that may be functionally important.	1.85741e-06
NZ_ANDC01000015.1\|WP_000571941.1\|200025_201522_+\|transcriptional-regulator	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	3.82119e-24
NZ_ANDC01000015.1\|WP_001263776.1\|194888_195896_-\|sugar-transferase	gnl\|CDD\|236626	PRK09814, PRK09814, sugar transferase.	1.32907e-150
NZ_ANDC01000015.1\|WP_000468351.1\|186240_187785_-\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	0
NZ_ANDC01000015.1\|WP_000567072.1\|201618_203610_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_ANDC01000015.1\|WP_000061665.1\|208471_209785_-\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0
NZ_ANDC01000015.1\|WP_075316641.1\|184674_186213_-\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_ANDC01000015.1\|WP_001042316.1\|203670_204591_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.55469e-11

>NZ_ANDC01000015.1|WP_001263776.1|194888_195896_-|sugar-transferase
MRVHITSIYGQSPRSIALISQKLVKDVGRQLGYDEMGIYFYNDHAETHGERSTRMDGIIAGLGRGDIVVFQVPTWNSTEFDELFLDKLQAYGARIITFVHDIVPLMFESNFYLLDRVIDMYNRSDVVILPTKAMHDYLIEKGMTTSKVLYQEVWDHPVNIDLPRPECQKVLSFAGDIQRFPFVNDWKENIPLIYYGDGSRLNSEANVHAQGWKDDVELMLSLSKRGGFGLCWSEDREELVERRYSRMNASYKLSTFLAAGLPIIANHDISSRDFIKQHGLGFTVETLEEAVEKINNMEKETYDSYVENVEKIATLLRNGYITKKLLIDAVHMLYR
>NZ_ANDC01000015.1|WP_000751408.1|193674_194880_-|glycosyl-transferase
MKKTIVLGADFQYRDQVMTTIKSIVSHNQHLTIYIINTDFPVEWFNILNHSLEQFDCRVKNIPISSDVFEGIPTLSHISVAGFFRWFIPIHLEEEIVLYLDSDVIVRGSLDPLFDINLEENLLGAVADHFSTLYYGDTAPVSFNSGVMLINNSLWKKEEIYNSLMRIADKGSAVGVGDQEYLNILTQNRWIDIGKQYNVQIGQDVNINAYGRPDLYHFYDDCEPVIVHYNSQDKPWNKYSQSRYRSEWWYYFGLEWSVIYAQQQKNLNRLTGKTLNLFTLTASDTLEHIEVLAKALPDYQFHIAARSDISEKLANLETYSNIKVYKLVINPILEELIRNCDVYLDINHSYEVEGILDKIKEENKPILAFDSTAHTTKNIEVISETMPELMVKRIREVGPLR
>NZ_ANDC01000015.1|WP_001865283.1|192436_193678_-|glycosyl-transferase
MKNRKAIALAADFGYQEQVKTIIKSICFHNQFIDFYILNDDFPVEWFQMMEYHLSKMDCTISNTKIFNEEIKHFKFQKPMPYPTYFRYFIPEVIHEDKVLYLDCDMIITSDLTSIFTLDISKYGVAAVRDDLLEEYDGKEDYFNSGLLLINNIFWREQGISQRLLDYTRENQGALQYHDQDVLNDVLCDNWLELDETYNYHTGADMLYNLFQQSERQLNRRKDLPKVIHYTATKPWKYLETSVRWRDIWWEYNRLEWRDIFTRWQVNDGVDVSLKKVLQPIHRAFIFTYSDSIEGIERLAKDLPNWQFHIAAYTQISEKLKQLEMHSNIKLYPLVYRFKLNELVENSDIYLDINHGDADTQVLEQVKKLGKDILSLSTTYHGQGKQFERVTDIIDYLKNERFKEHIRKEYCEK
>NZ_ANDC01000015.1|WP_000795050.1|191262_192447_-|glycosyl-transferase-family-8
MKNNVICLAGDNKSLNQIQTVIKSILCHNDRVSIYILNQDIASEWFRNIQRRLLNSHSCIFDIKLFDDTFKEFKTPRAHITYMAYARYYIPQLIDAEKVLYLDIDTLVVDNLDKLFEIELGDYPIAAILDGDGIHFNSGVMLINSLYWMRYRVTEKLLEITERELDNGIFGDQGVLNLLFDNNWLKLEDKYNAQVGNDLGAFYENWQGYFDRNFESPTIIHYCTHDKPWNTFSSSRFRETWWQYEQLDWNEVFNFETYLLPEPTFEKHFFTFTTSVDLLYIEELVELFPNSCFHIAAWTSFGPRLLKLATNSNVRLYPSITSPLFEQLMTKANYYLDISTSWKEIQFCQKAIEKSIPILSFNEAVTFEYRELSHCFINLEDMRQFLCKNGGNSD
>NZ_ANDC01000015.1|WP_075316616.1|190394_191282_-|glycosyltransferase-family-2-protein
MEAIVTDKLVSVIIPVYNAAPYLEGCVNTILGQTYQVFEILLIDDGSTDTSASICDQLSLRDNRIRVFHIENGGASKARNFGLARISPESQFVTFVDSDDWVKENYLEVLLAQQEKYNADIVISNYYIYRETEDIFGYYITDKDFVIEEISAQTAIDRQVHWHLNSSVFIVIWGKLYRRELFDTITFPIDKVFEDELVSVLLFIKSKKTILVNGSYYGYRIRPNSIMTSAFSSKIAEDLIYIFDSKLSEIILSGLDSTATVERYFWLMRDYKQRLEQENLQKTIIYKVISNRLSR
>NZ_ANDC01000015.1|WP_001263852.1|189137_190334_-|SP_1767-family-glycosyltransferase
MRVIKVKTISETLDYISKHTASVARFGDGEIDIIAGNSIPYQVYDSELAKRLERLLNRQSNEKLVICVSDVFDNLGRYNDFSQQFWRDHLYQYNDLYQKNCQAEWYGSTFISRPYMDLLDKSLSVTYFEQLKALWKNKDILIVEGETSRSGVGNDLFNDANTISRIICPSKDAFSSFYEIKETILEHSRGKLILLMLGPTAKLLAEDLSQLGHQAIDLGHIDSEYEWFKMGAVSKVKLSHKHTAEHNFDEDITLIEDNSYENQIVSKIGTSDRQYALTVTLTDDIWELEHLLQRCPNTNFHIAAPVYCSDRLKQLVGYPNYYLHEAITEEQFEVLLLNSDIYLDINHGEEVWNVVDRCITEGKTIYGIRRARKDNQYISFERTMDDFEYLCDTIKQNR
>NZ_ANDC01000015.1|WP_000772257.1|187784_189014_-|accessory-Sec-system-protein-translocase-subunit-SecY2
MKLLYIFEKNIILRKILITFSLIIIFLLGRYVPIPGVLISAYKGQDNNFATLYSTVTGGNLSQVGVFSLGIGPMMTTMILLRLFTIGKYSSGVSQKVQQFRQNVVMLVIAIIQGLAIAISFQYHNGFSLTKLLLATMILVTGAYIISWIGNLNAEYGFGGMTILVVVGMLVGQFNNIPLIFELFQDGYQLAIILFLLWTLVAMYLMITFERSEYRIPVMRTSIHNRLVDDAYMPIKVNASGGMAFMYVYTLLMFPQYIIILLRSIFPTNPDITSYNDYFSLSSIQGVVIYMILMLVLSVAFTFVNIDPTKISEAMRESGDFIPNYRPGKETQSYLSKICYLFGTFSGFFMAFLGGVPLLFALGNDDLRTVSSMTGIFMMITGMSFMILDEFQVIRIRKQYTSVFENEEN
>NZ_ANDC01000015.1|WP_000468351.1|186240_187785_-|accessory-Sec-system-protein-Asp1
MFHFIPSWYNENRTWYDNNYLWYFKPTNVGFDDTINQMKMFDYAGKESRLVVLNYMPNLRYYLHRYDLLESGYYSVFDDIQEIGNVRQQMIDFRQLNWPEGVDFTYTPFIVLVKKSGDLIAKVQFGEEGNLTHIDYFANEQIAKKYLFDDRGFLSSILYYDNGGEAYQDYLAPSGERIMREYLREGDHHVEINPKKAIHFLKLSYSDIEELIREKYLTYLHKEVSKSDTIIVSFNQVHNAFIVGNTSKGNLILSVFSERNNAHNVLEDYSSLSRANAIICDRLDIAAQLKEKIDKPVVHVSPFDTRLALGKSNQVRDLEIYFVVDRLSHKELQKSLTSLYKVMLKNNDIKVTFVSYEREFESRQLTYDYLKEATKVFDQKFFSLSDDDANQVLMQSDEVEKEKTRLSFTHPLSETDIINRLEYVRLIIDISKIPDLYTQVAGISSGIPQINTILTEFVEHRKNGYVIEEIQELEKAIPYYCEQLTNWNRSLIYSIDKINDYTGGQLVERIINSY
>NZ_ANDC01000015.1|WP_075316641.1|184674_186213_-|accessory-Sec-system-protein-Asp2
MLQVGEENWATKENIPNNMEWLFIKPDQISDFVTTENNYLTSSKLLQKLPRKISALLLTEQTYGPELSSLSSFFEVYEVFYPKDKHATGITEEFLRSKMAQRYDSSSPDQLIRQFYKGLFIGQYGEKLQVSQIQIRNDFEGVVNYQGNNYLELEGQFGENYSFLLNFAYNIPFSSDFYNELFLEHIIEGDIDIRLVISLIVDGSVDDIAKEWYFEKEDLNQLISLESDISGSLAVKLFAKGKGIVKLGPLHRRNGRGGLGTFLLGGERHIDAIGHEFMTYFDPVDFKPPLTVYFSGFRSAEGFEGFWMMKSMKTPFMLICDPRLQGGAFYIGSKEYEQKIVDAIQEKLAFLNFSSDQLILSGLSMGTYGATYHGAKLNPHAIIIGKPIFNLGTVAQRERLERPDGFATSLDIQLLNQGDLTSSSSEKLNNYFWKSIEEGDFSNTTFALAYMKNDDYDATAFSDLLQYFRGKKHKILGRGWDGRHGDCSAEVGAWFTSQYRRMLSNDFGRKEE
>NZ_ANDC01000015.1|WP_000104405.1|183685_184678_-|accessory-Sec-system-protein-Asp3
MSTISYIYWDDFSRFSYNFGTKLQFLGKSVCFENPLAPSSTNLYTWSSQTNYQSKRISPNLPLLRKGTRYSLSLNAELDLVSSLFVRIEFYNRFNESVGFELLKKDSIIFIYPKEAYTYTISLINAGCSDFTFHYLKLEEVTDSVIQEKNLSTEFTIEEHQDVLNLLLVEKKDSVYINKIESISQLQQKVELVSNPSLNSDSLILPKLEKGLEDALKVFPNIKINVIAYGTQGNFAALYYAKKFPRITAYINDCFAPFGILLKSLPHLTAKQQIFLREVWDTRETSPNVKHYGLVSENSSLNLVSMILSGNEHLPYLTLLKKQDDNYDSL
>NZ_ANDC01000015.1|WP_000571941.1|200025_201522_+|transcriptional-regulator
MIENFLEKNILNKVKLLTLCYDTPSLSLDTACNRLHLSPVELKNYCHKLNVLFGHKLSIHIQKERILCKLNKLTQEDALKIVYNESNTLQLLKFLIDDSSDKKSLVAFGNDLFLSRSSVYRLRENLIPLIKDLGLSLSKNTIVGDEYRIRYLIAYLTTKFGIKIYDLSALDIKIIRQFLFESGTNIRPTTHLSDIFIFFDTLFILTWKRHHHKVKIPNSKLFSSLKKIFIYEELNTCVKSIVQPYFNVIFNSEDMDYIFLIYLTSANSFAAQKWTETHVDEVLAIFKSLPKFQMLLQPLKEALPYSDTYYDELVKVTIYFSRNFIVGLNQLIPETLSFPSTFYPGNNPKLISIIEPIVTHWLTEIGESKFKKTHFFLLCAHLERVIKNSMPPINIVLLTTDFINNEILKDYILQSLSTDKIRFHSYYLLTDNISQISTLKPDLIITNRKLFTYVTKELATNSLVAHIDYNDTPSQISNIQTIISNIKEEKYRKIFDKI
>NZ_ANDC01000015.1|WP_000567072.1|201618_203610_-|excinuclease-ABC-subunit-B
MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVLGEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYEMEQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADKITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQQQMQEAAELLDFELAAQIRDVILELKAID
>NZ_ANDC01000015.1|WP_001042316.1|203670_204591_-|CPBP-family-intramembrane-metalloprotease
MNKRILNSQFAVYKNWPSWLLLLFACFMVYLFFFVGLTLGGVGIVLVSSVLYKFSSYTFFEFINLFNNIYGELGTFSFSAFLLLIWVKFVEKRPFSELGFSTKFKRTLWSLIKGWSIGFILFSISVITAYILGGLDFHSYDVSKATIFYVVTLLPFWLIQSGTEELLTRGWLLPLINHRFHLAVAIGVSSTLFGILHLVNAHVTFLSIVSIICSGVLMSLYMIKSGNIWSVAALHGAWNFSQGNLYGIAVSGQKAGASLLHFTVKENAPDWISGGAFGIEGSLISIFVLLAAIIYLLWLIKTEETD
>NZ_ANDC01000015.1|WP_000681005.1|204773_206957_+|ABC-transporter-permease-subunit
MKHKLKAFTLALLSIFFVFGGKVSAETVNIVSDTAYAPFEFKDSDQTYKGIDVDIVNEVAKRAGWNVNMTYPGFDAAVNAVQSGQADALMAGTTVTEARKKVFNFSDTYYDTSVILYTKNNNKVTNYKQLKGKVVGVKNGTAAQSFLEENKSKYGYKVKTFDTSDLMNNSLDSGSIYAAMDDQPVVQFAINQGKAYAINMEGEAVGSFAFAVKKGSGHDNLIKEFNTAFAQMKSDGTYNDIMDKWLGKDATKTSGKATGNANEKATPVKPSYKIVSDSSFAPFEYQNGKGKYTGFDMELIKKIAKQQGFKLDISNPGFDAALNAVQSGQADGVIAGATITEARQKIFDFSDPYYTSSVILAVKKGSNVKSYQDLKGKTVGAKNGTASYTWLSDHADKYNYHVKAFDEASTMYDSMNSGSIDALMDDEAVLAYAINQGRKFETPIKGEKSGDIGFAVKKGANPELIKMFNNGLASLKKSGEYDKLVKKYLSTASTSSNDKAAKPVDESTILGLISNNYKQLLSGIGTTLSLTLISFAIAMVIGIIFGMMSVSPSNTLRTISMIFVDIVRGIPLMIVAAFIFWGIPNLIESITGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPSGQMEASRSLGISYGKTMQKVILPQAVRLMLPNFINQFVISLKDTTIVSAIGLVELFQTGKIIIARNYQSFRMYAILAIMYLVIITLLTRLAKRLEKRLK
>NZ_ANDC01000015.1|WP_000818887.1|206956_207697_+|amino-acid-ABC-transporter-ATP-binding-protein
MAELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGKSTFLRTLNLLESITSGKVVVDGFELSNPKTDIDKARENIGMVFQHFNLFPHMSVLENITFAPIELGKESKEAAEKHGMELLEKVGLADKANAKPDSLSGGQKQRVAIARSLAMNPDILLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGRFLEDGTPEQIFDTPQHPRLQDFLNKVLNV
>NZ_ANDC01000015.1|WP_000656279.1|207845_208196_+|hypothetical-protein
MKDYINRILHFIKEHMTYHVNFIDDFLDIKWEKVSNIHLRFWTTIIAYLVIFILSISTVILNLVLLFQGFLTQNPIIYLLFFITLVCAFYFAYKFITYTPTIVKNALQYIKKLKNV
>NZ_ANDC01000015.1|WP_000502594.1|208287_208446_-|hypothetical-protein
MGDKPISFRDKDGNFVSAADVWNAEKLEELFNTLNPNRKLRLEREKLAKEKG
>NZ_ANDC01000015.1|WP_000061665.1|208471_209785_-|GTPase-ObgE
MSMFLDTAKISVKAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVNEGLRTLMDFRYNRNFKAKAGEKGMTKGMHGRGAEDLIVSLPPGTTVRDATTGKVITDLVEHDQEFVVARGGRGGRGNIRFATPRNPAPEIAENGEPGEERELQLELKILADVGLVGFPSVGKSTLLSVVSAAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYDDYVSINNELETYNLRLMERPQIIVANKMDMPDSEENLAAFKEKLAANYDEFDDMPMIFPISSLAHQGLENLMDATAELLANTEEFLLYDETDMQEDEAYYGFNEDERPFEITRDDDATWVLYGDKLEKLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGNFEFEFVD
>NZ_ANDC01000015.1|WP_000863865.1|209845_209974_-|DUF4044-domain-containing-protein
MAFGDNGQRKKTGFEKLTLFVVILMVLVTVGGLVFGAISAIM
>NZ_ANDC01000015.1|WP_000244039.1|210151_211393_+|aminopeptidase
MVLQDFDNLLKKYAQLIISKGLNVQKGHTLALTIDVEQVHLARLLTEAAYEKGASEVIVDYTDDFITRQRLLHASDEVLTNVPQYTVDKSLALLNKKASRLVVKSSNPNAFATVDPKRLSETTRATAIALEEQSRAIQANKVSWNVAAAAGREWAALVFPELKTSDQQVDALWDTIFKLNRIYEDDPIAAWDAHEAKLLEKATRLNQEQFDALHYTAPGTDLTLGMPKNHIWEAAGSLNAQGETFIANMPTEEIFSAPDYRRADGYVTSTKPLSYAGVIIENMTFTFKDGKIINVTAEKGQETVQRLIEENDGARSLGEVALVPHKTPISLSGLIFFNTLFDENASNHLAIGSAYAFNVEGGTEMTSQELDEAGLNRSSTHVDFMIGSEQMDIDGIRADGTAVPIFRNGEWAI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

101169 : 111441

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000638889.1\|101169_102315_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	4.3e-29	28.7
WP_000033715.1\|102561_103014_+	hypothetical protein	NA	NA	NA	NA
WP_000043887.1\|103056_104406_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-32	25.5
WP_000024620.1\|104580_104916_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	8.9e-20	39.4
WP_001269901.1\|104999_106166_-	chorismate synthase	A0A291AU41	Pandoravirus	9.3e-40	34.1
WP_001195736.1\|106166_107234_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_000707048.1\|107327_108005_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	5.3e-88	68.4
WP_001037596.1\|108004_109162_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.3e-139	66.0
WP_000721268.1\|109296_111441_+	LTA synthase family protein	W6LM83	Streptococcus_phage	6.3e-260	67.5

DBSCAN-SWA_2

287591 : 298324

Streptococcus_phage(84.62%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000767486.1\|287591_288419_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.1e-124	78.0
WP_000287943.1\|288459_288816_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000966769.1\|288817_289294_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.6e-38	50.9
WP_000232154.1\|289349_290531_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	9.1e-168	75.3
WP_001198082.1\|290592_291141_-	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	1.4e-54	57.9
WP_000158397.1\|291209_292301_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.9e-165	78.0
WP_000603271.1\|292433_293069_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001868293.1\|293112_293217_-	hypothetical protein	NA	NA	NA	NA
WP_079254671.1\|293201_293363_+	hypothetical protein	NA	NA	NA	NA
WP_001867099.1\|293338_294202_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.1e-109	70.4
WP_000358198.1\|294207_294534_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000364568.1\|294564_295428_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.5e-74	50.0
WP_000715592.1\|295447_296083_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_001144242.1\|296171_296831_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.5
WP_000178150.1\|296849_297560_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-13	29.1
WP_001185985.1\|297559_298324_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-14	24.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_ANDC01000008

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3721 : 11275

Streptococcus_phage(50.0%)

integrase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000353149.1\|3721_4378_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-22	31.8
WP_000594360.1\|4387_5665_-	ABC transporter permease	NA	NA	NA	NA
WP_000508795.1\|6406_6568_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_001867107.1\|6740_6950_-\|transposase	transposase	NA	NA	NA	NA
WP_001865698.1\|7075_7336_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001122304.1\|7357_7558_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_000640620.1\|7719_8124_-	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	1.3e-20	43.6
WP_001872365.1\|8123_8390_+	hypothetical protein	Q77YW7	Streptococcus_phage	9.2e-20	65.2
WP_071659971.1\|8392_9007_+\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001068667.1\|9151_9499_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000595708.1\|10078_11275_-	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	4.6e-103	54.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_ANDC01000022

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CRISPR-Cas detection and classification

Crispr_ID: NZ_ANDC01000022_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANDC01000022_1

101121-101196

Orphan

Consensus_repeat	Method
TGATGTTAAACAAGTATCAGTTGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_ANDC01000022_1

>merge|NZ_ANDC01000022|1|101121-101196|CRISPRCasFinder
TGATGTTAAACAAGTATCAGTTGCTAAAGCAAGCGTGTTGCCAAGTACTGGTGATGTTAAACAAGTATCAGTTGCT

>NZ_ANDC01000022|1|1|101121-101196|CRISPRCasFinder
TGATGTTAAACAAGTATCAGTTGCT	AAAGCAAGCGTGTTGCCAAGTACTGG
TGATGTTAAACAAGTATCAGTTGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANDC01000022.1\|WP_000162146.1\|92497_93838_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341046
NZ_ANDC01000022.1\|WP_001867987.1\|91534_92227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000022.1\|WP_000938679.1\|97958_98144_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000022.1\|WP_001282475.1\|95137_95509_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000022.1\|WP_000822468.1\|96931_97957_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NZ_ANDC01000022.1\|WP_157784605.1\|102059_102168_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274751
NZ_ANDC01000022.1\|WP_000191926.1\|95692_95950_+\|DUF3850-domain-containing-protein	unknown	unknown	gnl\|CDD\|372409
NZ_ANDC01000022.1\|WP_000481327.1\|94040_95024_+\|GMP-reductase	unknown	unknown	gnl\|CDD\|235479
NZ_ANDC01000022.1\|WP_000208122.1\|98140_98338_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_ANDC01000022.1\|WP_000129105.1\|98720_99020_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000022.1\|WP_000447421.1\|96215_96659_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANDC01000022.1\|WP_001042360.1\|101282_101993_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|223021

Protein	Function_ID	Function_description	E-value
NZ_ANDC01000022.1\|WP_000191926.1\|95692_95950_+\|DUF3850-domain-containing-protein	gnl\|CDD\|372409	pfam12961, DUF3850, Domain of Unknown Function with PDB structure (DUF3850). The search results from NCBI sequence alignment indicates a conserved domain belonging to ASCH superfamily. Dali searching results show that the protein is a structurally similar to the PUA domain, suggesting it may be involved in RNA recognition. It has been reported that the deletion of PUA genes results in impaired growth (RluD) and competitive disadvantage (TruB) in Escherichia coli. Suggestions have been put forward that, apart from their usual catalytic role, certain PUS enzymes (e.g. TruB) may also act as chaperones for RNA folding. The interface interaction indicates that the biomolecule of protein NP_809782.1 should be a dimer.	1.25228e-26
NZ_ANDC01000022.1\|WP_000481327.1\|94040_95024_+\|GMP-reductase	gnl\|CDD\|235479	PRK05458, PRK05458, guanosine 5'-monophosphate oxidoreductase; Provisional.	0
NZ_ANDC01000022.1\|WP_000208122.1\|98140_98338_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.56498e-16
NZ_ANDC01000022.1\|WP_000162146.1\|92497_93838_+\|MFS-transporter	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.42202e-59
NZ_ANDC01000022.1\|WP_000822468.1\|96931_97957_+\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	2.54502e-32
NZ_ANDC01000022.1\|WP_157784605.1\|102059_102168_+\|hypothetical-protein	gnl\|CDD\|274751	TIGR03726, strep_RK_lipo, putative cross-wall-targeting lipoprotein signal. The YSIRK signal domain targets proteins to the cross-wall, or septum, of dividing Gram-positive bacterial. Lipoprotein signal motifs direct a characteristic N-terminal cleavage and lipid modification for membrane anchoring. This Streptococcal-only signal peptide variant appears to be a hybrid between the two, likely directing protein targeting of nascent surface lipoproteins to the cross-wall. Nearly all members of this family have the characteristic LPXTG cell wall anchor signal at the C-terminus.	4.38215e-05
NZ_ANDC01000022.1\|WP_001042360.1\|101282_101993_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	1.72846e-05

>NZ_ANDC01000022.1|WP_000129105.1|98720_99020_+|hypothetical-protein
MTDETKKVYLRDLRNLGKQGGATARLEDGTELFLKPDYAVRTAKGYVDGIPRDVEFHLTYRSIFNQIRTIKKDGHLVARKERSPSGLVLQLTGKGYKRP
>NZ_ANDC01000022.1|WP_000208122.1|98140_98338_+|helix-turn-helix-transcriptional-regulator
MTTITQNRVKELRKQAGLSQQALADQIGVMRKTISHWELGNHRISTDNAKKLSQFFQVSIDDLLE
>NZ_ANDC01000022.1|WP_000938679.1|97958_98144_+|hypothetical-protein
MLQDEFRPIPHKVLTIGRSPKESVIAIPKAIFNLPPEEKAQALKELEEDMEQHKAKGGDST
>NZ_ANDC01000022.1|WP_000822468.1|96931_97957_+|replication-initiator-protein-A
MKRISARQVQSSERFYRIPKIFVESPFYKSMSTDAKFTYAILKDRFELSLKNNWIDKNGDVYLIYTVTELQEILGYGNKKVIKLKKELQEYGLLEEVRQGLNKPNLLYLGNVDYQNVPTEEIHSKPSSVAEVSKQHFQKNQGNVKMTRQKMSKRHANDTENSETELSNDTNRYQGDASLDILSASDSFQMGQHGFLSSKTINRLSLFGKEAKLLENKIYQAKRQVEKDYSHLLQHQEIIYGEVWSQELEREVDKLIFKIKTGENEGKAIKNIPGYFYKMMVRFWKMALLIEKEQGFIALSNQSDYAKSFPEECPSLISYYYPNKLSEKELNQYLTTLRMEE
>NZ_ANDC01000022.1|WP_000447421.1|96215_96659_+|hypothetical-protein
METGIKKGHFKESVEKRIHSQHMRIEPNISNRSTRIRDISYDQSKKLYRVTIVRNGIRYGGKHFKKLGEAQKYKKQLLEDIKRKIKESQMSQTAIAQLTKNMMVFNVVVLSLGYFNVIPYKWSLILWGSAVFTAIFNEISKQIPDEK
>NZ_ANDC01000022.1|WP_000191926.1|95692_95950_+|DUF3850-domain-containing-protein
MTQHLLNCYPEYFEAIMDGTKTFECRYNDRDFKVGDELLLREYDPQKGYTYRCIVRKITYILSDFIGLKDGYVILGVTNEPIDYF
>NZ_ANDC01000022.1|WP_001282475.1|95137_95509_+|hypothetical-protein
MSDNIEIIMDIETLDIFEVIDLDEEKGVTVSDSETFPKEEKASPYDDLNRIWLRNGYYYKPSSLLWEVIENGIIHDLSSRNKHGTYPYYQNLRDGTWGHVKQLTQEEALWLTLELNPDLMNYV
>NZ_ANDC01000022.1|WP_000481327.1|94040_95024_+|GMP-reductase
MFNDIPVFDYEDIQLIPNKCIISSRSQADTSVKLGNYTFKLPVIPANMQTIIDEEVAETLACEGYFYIMHRFNEEERKPFIKRMHDKGLIASISVGVKDYEYDFVTSLKEDAPEFITIDIAHGHSNSVIEMIQHIKQELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCSKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHLESPGKLVEVDGQQFKEYYGSASEYQKGEHKNVEGKKILLPVKGRLEDTLTEMQQDLQSSISYAGGKELDSLRHVDYVIVKNSIWNGDSI
>NZ_ANDC01000022.1|WP_000162146.1|92497_93838_+|MFS-transporter
MTKKGWRIMPAIITTAILGFSGILIETSMNVTFPLLMKEFGVNPAVIQWVTTGNLLAVAVTVPLSAFMIKNLSERQIFTLANVLFLSGVLIDSFAPNLAILLVGRVLQGVGTGLALPLLFHIILTQIPMERRGLMMGVAAMVTLLAPAVGPTYGGVISGMLGWKMIFMLLAPILIISTFIGLASIPKRQVRINDKLNFPAFVSLGIGLATLLLAIEKMSIFYLLVAIVSFVIFYYLNKQLEFLNLNVFKDKDFSILLYGVLAFQMIPLALSFLLPNLLQLVLHQTSTKAGLFMFPGAIAVVFLSPFAGYLLDKIGAFKPIMIGISLSLIGLIGTAIFIPAKFVVVLLAFDILTKIGMGIGASNMVTTALTKLKPAQSADGNSILNTLQQFAGAFATAVASQIFTIGQVAIPKNGAIIGSQFAVLFVIIVVILAIVGLTYLRKRKAI
>NZ_ANDC01000022.1|WP_001867987.1|91534_92227_-|hypothetical-protein
MLIPKKIVAFASNESENNFFITLKTYFNYLFSIQIITDISTLNHADFDGSFAFHDIETSIPHLVIDSNYLAISQTNSKTEANDIKTFSELSKTMTEFHYMLNFDLFNHLPYRFRLHNKDGQTIYSNHKPEDPFDIYPEEEYPIDKWVQNSLIEKKAKELHLLLPGASQDYILVQSYKRLENDSGQLVGYIEHVHNIKPLLEGYLKESGQAIVGWSDVTSGASISNDDFEL
>NZ_ANDC01000022.1|WP_001042360.1|101282_101993_+|LPXTG-cell-wall-anchor-domain-containing-protein
MNKRKLLTVLSIASVAVLSSVTFADEITPSDPTAPSTPLITPTPVDPGTPTDTTKPSTPVDPGTPTDTTKPSTPVDPGTPTDTTKPSTPVDSGTSTNPSDSEATNTNLGTKPTDVVKPETPKIPEVPSTVTPDVIDKVDKETGNITIKPIQISPDKTIIGTQNGNVIIRDSSGSHLVSASEVGGRLNEDGTVTIKDSSGKTKTLPRTGEAKGFLSIIGATILSFVAYLFKQRVTLN
>NZ_ANDC01000022.1|WP_157784605.1|102059_102168_+|hypothetical-protein
MNSQETKGHGFFRKSKAYGLVCGIALAGAFTLATSQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_ANDC01000024

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

33623 : 42614

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000998735.1\|33623_34220_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	1.1e-15	29.4
WP_000575545.1\|34311_35568_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	7.8e-93	51.7
WP_000968655.1\|35572_36550_+	nucleoid-associated protein	NA	NA	NA	NA
WP_000472259.1\|36551_37154_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.1e-20	40.1
WP_000826946.1\|37165_38887_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-40	26.7
WP_000647638.1\|38887_40621_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.1e-50	31.0
WP_000746859.1\|40634_40832_+	hypothetical protein	NA	NA	NA	NA
WP_000222544.1\|40895_42614_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.4e-278	84.8

DBSCAN-SWA_2

95418 : 104802

uncultured_Caudovirales_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000201088.1\|95418_96180_+	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	1.5e-25	40.7
WP_000136509.1\|96200_96749_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_000735588.1\|96987_97950_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	3.3e-83	50.3
WP_000588576.1\|97946_98921_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	3.6e-05	21.2
WP_000614751.1\|98917_99679_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.7e-18	28.6
WP_000162771.1\|99740_100769_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001015250.1\|100906_101749_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	8.5e-27	35.8
WP_000246601.1\|101843_103964_+	type I DNA topoisomerase	E3T4K4	Cafeteria_roenbergensis_virus	3.1e-102	37.6
WP_000120355.1\|104100_104802_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.2e-35	39.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage