CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_ANEC01000011	Streptococcus agalactiae BSU260 ctg120000807536, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000030	Streptococcus agalactiae BSU260 ctg120000807555, whole genome shotgun sequence	1 crisprs	NA	4	3	2	0
NZ_ANEC01000028	Streptococcus agalactiae BSU260 ctg120000807553, whole genome shotgun sequence	0 crisprs	DinG	0	0	1	0
NZ_ANEC01000020	Streptococcus agalactiae BSU260 ctg120000807545, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_ANEC01000006	Streptococcus agalactiae BSU260 ctg120000807531, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000007	Streptococcus agalactiae BSU260 ctg120000807532, whole genome shotgun sequence	0 crisprs	cas3	0	0	0	0
NZ_ANEC01000022	Streptococcus agalactiae BSU260 ctg120000807547, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000016	Streptococcus agalactiae BSU260 ctg120000807541, whole genome shotgun sequence	0 crisprs	cas3,csa3	0	0	1	0
NZ_ANEC01000021	Streptococcus agalactiae BSU260 ctg120000807546, whole genome shotgun sequence	1 crisprs	csm6	0	0	1	0
NZ_ANEC01000013	Streptococcus agalactiae BSU260 ctg120000807538, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000005	Streptococcus agalactiae BSU260 ctg120000807530, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000025	Streptococcus agalactiae BSU260 ctg120000807550, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_ANEC01000024	Streptococcus agalactiae BSU260 ctg120000807549, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000019	Streptococcus agalactiae BSU260 ctg120000807544, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000014	Streptococcus agalactiae BSU260 ctg120000807539, whole genome shotgun sequence	0 crisprs	WYL	0	0	0	0
NZ_ANEC01000031	Streptococcus agalactiae BSU260 ctg120000807556, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000015	Streptococcus agalactiae BSU260 ctg120000807540, whole genome shotgun sequence	0 crisprs	NA	0	0	0	1
NZ_ANEC01000003	Streptococcus agalactiae BSU260 ctg120000807528, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000027	Streptococcus agalactiae BSU260 ctg120000807552, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
NZ_ANEC01000023	Streptococcus agalactiae BSU260 ctg120000807548, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000010	Streptococcus agalactiae BSU260 ctg120000807535, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000002	Streptococcus agalactiae BSU260 ctg120000807527, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000029	Streptococcus agalactiae BSU260 ctg120000807554, whole genome shotgun sequence	1 crisprs	cas9,cas1,cas2,csn2	0	7	1	0
NZ_ANEC01000008	Streptococcus agalactiae BSU260 ctg120000807533, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_ANEC01000026	Streptococcus agalactiae BSU260 ctg120000807551, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000004	Streptococcus agalactiae BSU260 ctg120000807529, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000012	Streptococcus agalactiae BSU260 ctg120000807537, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000001	Streptococcus agalactiae BSU260 ctg120000807526, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000009	Streptococcus agalactiae BSU260 ctg120000807534, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000017	Streptococcus agalactiae BSU260 ctg120000807542, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_ANEC01000018	Streptococcus agalactiae BSU260 ctg120000807543, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_ANEC01000021_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANEC01000021_1

53099-53174

Orphan

Consensus_repeat	Method
AGCAACTGATACTTGTTTAACATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_ANEC01000021_1

>merge|NZ_ANEC01000021|1|53099-53174|CRISPRCasFinder
AGCAACTGATACTTGTTTAACATCACCAGTACTTGGCAACACGCTTGCTTTAGCAACTGATACTTGTTTAACATCA

>NZ_ANEC01000021|1|1|53099-53174|CRISPRCasFinder
AGCAACTGATACTTGTTTAACATCA	CCAGTACTTGGCAACACGCTTGCTTT
AGCAACTGATACTTGTTTAACATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANEC01000021.1\|WP_000938679.1\|56150_56336_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_001867987.1\|62067_62760_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_001042362.1\|52346_53012_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|223021
NZ_ANEC01000021.1\|WP_000208122.1\|55956_56154_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_ANEC01000021.1\|WP_000134095.1\|45165_47856_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NZ_ANEC01000021.1\|WP_000822468.1\|56337_57363_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NZ_ANEC01000021.1\|WP_000488485.1\|43465_44248_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319758
NZ_ANEC01000021.1\|WP_001282475.1\|58785_59157_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_000371901.1\|42952_43444_-\|DUF3801-domain-containing-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_000447421.1\|57635_58079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_001037292.1\|50824_51184_-\|PrgI-family-protein	unknown	unknown	gnl\|CDD\|378907
NZ_ANEC01000021.1\|WP_000567358.1\|44539_45145_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_017646869.1\|51245_52280_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_ANEC01000021.1\|WP_000162146.1\|60456_61797_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341046
NZ_ANEC01000021.1\|WP_000191926.1\|58344_58602_-\|DUF3850-domain-containing-protein	unknown	unknown	gnl\|CDD\|372409
NZ_ANEC01000021.1\|WP_000606554.1\|44247_44520_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_017645960.1\|48344_48488_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_000129105.1\|55274_55574_-\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000021.1\|WP_000176428.1\|48492_50844_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|274279
NZ_ANEC01000021.1\|WP_000481327.1\|59270_60254_-\|GMP-reductase	unknown	unknown	gnl\|CDD\|235479

Protein	Function_ID	Function_description	E-value
NZ_ANEC01000021.1\|WP_000191926.1\|58344_58602_-\|DUF3850-domain-containing-protein	gnl\|CDD\|372409	pfam12961, DUF3850, Domain of Unknown Function with PDB structure (DUF3850). The search results from NCBI sequence alignment indicates a conserved domain belonging to ASCH superfamily. Dali searching results show that the protein is a structurally similar to the PUA domain, suggesting it may be involved in RNA recognition. It has been reported that the deletion of PUA genes results in impaired growth (RluD) and competitive disadvantage (TruB) in Escherichia coli. Suggestions have been put forward that, apart from their usual catalytic role, certain PUS enzymes (e.g. TruB) may also act as chaperones for RNA folding. The interface interaction indicates that the biomolecule of protein NP_809782.1 should be a dimer.	1.25228e-26
NZ_ANEC01000021.1\|WP_000162146.1\|60456_61797_-\|MFS-transporter	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.42202e-59
NZ_ANEC01000021.1\|WP_001037292.1\|50824_51184_-\|PrgI-family-protein	gnl\|CDD\|378907	pfam12666, PrgI, PrgI family protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 116 and 146 amino acids in length. This protein is found in an operon that is part of a Type IV secretion system.	0.00186887
NZ_ANEC01000021.1\|WP_001042362.1\|52346_53012_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	8.6981e-05
NZ_ANEC01000021.1\|WP_017646869.1\|51245_52280_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	9.75406e-06
NZ_ANEC01000021.1\|WP_000208122.1\|55956_56154_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.56498e-16
NZ_ANEC01000021.1\|WP_000134095.1\|45165_47856_-\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	1.18534e-22
NZ_ANEC01000021.1\|WP_000822468.1\|56337_57363_-\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	2.54502e-32
NZ_ANEC01000021.1\|WP_000488485.1\|43465_44248_-\|hypothetical-protein	gnl\|CDD\|319758	cd16427, TraM-like, C-terminal domain of transfer protein TraM. This family contains the C-terminal domain of transfer protein TraM of the G+ broad host range Enterococcus conjugative plasmid pIP501 and similar proteins. The protein localizes to the cell envelope and is part of the plasmid transfer system that is accessible from outside of the cell. TraM displays a fold similar to the type IV secretion system (T4SS) VirB8 proteins from A. tumefaciens and B. suis (G-) and to the transfer protein TcpC from C. perfringens plasmid pCW3 (G+), reinforcing the prediction that TraM performs a key role in the secretion process, which is underlined by its surface accessibility. It is also structurally related to members of the nuclear transport factor-2 (NTF-2)-like superfamily with a high similarity to the NTF-2 protein from Rattus norvegicus. TraM (categorized as T4SS VirB8-like class GAMMA) does not possess the binding pocket of classic VirB8 class ALPHA proteins, recognized by VirB8 interaction inhibitors.	2.28933e-31
NZ_ANEC01000021.1\|WP_000176428.1\|48492_50844_-\|DUF87-domain-containing-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	9.6429e-17
NZ_ANEC01000021.1\|WP_000481327.1\|59270_60254_-\|GMP-reductase	gnl\|CDD\|235479	PRK05458, PRK05458, guanosine 5'-monophosphate oxidoreductase; Provisional.	0

>NZ_ANEC01000021.1|WP_001042362.1|52346_53012_-|LPXTG-cell-wall-anchor-domain-containing-protein
MNKRKLLTVLSIASVAVLSSVTFADEITPSDPTAPSTPLITPTPVDPGTPTDTTKPSTPVDPGTPTDTTKPSTPVDSGTSTNPSDSEATNTNLGTKPTDVVKPETPKIPEVPSTVTPDVIDKVDKETGNITIKPIQISPDKTIIGTQNGNVIIRDSSGSHLVSASEVGGRLNEDGTVTIKDSSGKTKTLPRTGEAKGFLSIIGATILSFVAYLFKQRVTLN
>NZ_ANEC01000021.1|WP_017646869.1|51245_52280_-|hypothetical-protein
MNSQETKGHGFFRKSKAYGLVCGIALAGAFTLATSQVSADQVTTQATTQTVTQNQAETVTSTQLDKAVDTAKKAAVAVTTTTAVNHATTTDAQADLANQTQAVKDVTAKAQANTQAIKDATAENAKIDAENKAEAERVAKANKAGQAEVDARNKAGQAAVDARNKAKQQAQDDQKAKIDAENKAESQRVSQLNAQNKAKIDAENKDAQAKADATNAQLQKDYQTKLANIKSVEAYNAGVRQRNKDAQAIRLIQGDDLFYTYAWRFVEATGDCQAGITILKILQDDLNYFFAIGKLSQKQYSQWLEKWLSFLERGRIAFKGEKDFERYFQDQTEANRSLFSDFNL
>NZ_ANEC01000021.1|WP_001037292.1|50824_51184_-|PrgI-family-protein
MNKLGSEFFKAIDQFERGIIGSFTWRQILMFFGIVLGVGLATVISLLQLPSILFYLSLVLTVPPAFIYGIKKDEHIKEVITFRLKVQERAYQTEYESEENYGAFIPQKGIQEWNDPNEN
>NZ_ANEC01000021.1|WP_000176428.1|48492_50844_-|DUF87-domain-containing-protein
MTLTKTEKERAKQLQRALKASTQNTIQYTSLFEDGLMHIVDESYSKTWQLGDTNYITGSEDEKLDIIEYYVDALNGLDSENTYQLTILNRPVPTTLLDQITYDLEGDERDVFRKEYNNIIRSRFAKDQNNFKVEKFVTVSTRAKDRKQAYRKLNDVDTHFTTQFQLVDVLLKSLDGTERLNIFADLLRGNPYLDVDYKDVRISGLSTKSFIAPGRLWFQPDQFMMDKKYCKILFPRTFPAFLNDRLIKSLTDIGIELAISIHAQPYDVAEAVKKVNTAEAGVKMDMVKSQVSAAQKGISSNLAVSSVAQDTADEAEKWKTEINDNDQKMFSGVFLVMVKADSAEELADYTSRIKQAGRKHVIEFEETYYHQEEALNSMLPIGKTYIDVKRRFMRDMTTTNIATQIPFTNTDLQSQSPLANYYGQNQISNNIISLDRQRDLYTSSGVILGSSGSGKSVFVKINEVIPAILRFPNDRVIIVDPEEEYVDIGHAFGAQVIDIYPGTKTHFNLMDIPDLNKLRDEDKDFVGQKASLIMGLFENILQEVTDDDVSLIDRVTHLCYEQITDRTPTLKDWHDILLEQPEEEAQSLALKSESYTKGSQDIFAYETNVDLNNQVVIFNLKKLSGKLKPFAMMVIQDYIWQHVVDHKDEFVTRVYFDEMQNQFETDDQAAFFSKMYARIRKYGSIPTGITQNVETLLSRKEGRNLLYNSEFLVLLKQKKTTIPYLLKTINLTDALVRYIEKPKAIGTGLIIAGTTTVPFENPIPEDTELFRLVATDAYRKMES
>NZ_ANEC01000021.1|WP_017645960.1|48344_48488_-|hypothetical-protein
MKKQTKKATLPYRGSLLSQSILSEQQKSRKTSIFIFLTVIGETLCFL
>NZ_ANEC01000021.1|WP_000134095.1|45165_47856_-|CHAP-domain-containing-protein
MTEEKQDLRSRVVRKRQIKESVHRHNQSSARKAQKAAKGELQVATKELKEAREAYQKAQTDFRAGIIDDEALKKAQEKLKQAQAKYKDAKKVKKKVRKTNPTLSQKVRQTGRRITKRTGQEILEMGFEQDDTLSDLVRTKHQIRQTQAMAKQAGRATGKGIKLTYRGAKGTVKLGAKGTKYAYHQTRKGSVKATQETVKVASKTAQTLVATSKALVSAIAPIIANPITWAVTGVISLLLLIVILVSSVFSSNVVQQNEFTLNQSWLHISKVDRQKSSDKVDYYTDIDSILLYMNYRYGGEWEPDARWDDGFGGKVTGALGFNHFSDALDDIWKEENQDIDHLKTMAELYTNGKEWIKFSKDDLEEYKEILDSQAETGKYLAYQELSNPFYASDDDKAESDYLTIAKRYGYTDKDTIDPTTTLQAKASQKLYAVMDGKVTVTKKDLKGEKTKTTNLIIEDTDARFIYYDVSQSRVKTGDKVEAGRELATVSGDTQKIAYAKRYGEVDDKDSTWLKEIRDKDVSYGYITKTKKGKKEVWVLTNPGFYFPFVKYVETTTVTQEPYEMSGRAKQLYDLIKKILPHATDNGIAAIAGCFGVESSINPKRAEGDYLSPPVGSSASSWDDEAWLTIGGPAIYGGGYPNIIHRGLGLGQFTDTSDGANRNTLLREFAKSKGKKWYSLELQVQFMLEGDNPYYINIFKRIATSQGDVDSLTAEFLAKWEGVPGNKLAQRQAIAKQALMWFKQPTHSGGASTLQSSWNFPKEYSSKLKSYPSAATVSRSLNGNTYPIGQCTWYVYNRLSEAGAPAVNWLGNGQDWVRNLVAKGWTFSNKPVAGAVCSTAGGFDYTMPTYGHVSYVEHVNGDGTFLVSECNVMGIQNQIHWAVKSRQSYYTFAIPPK
>NZ_ANEC01000021.1|WP_000567358.1|44539_45145_-|hypothetical-protein
MIDTFKVKWFKRGMSLLVLILVFFLGLGFGQMGNSSQSKDRPKQTATKKTRTNTITQTQVKEFLVAYYTKKDLEENRNRYKDYMTEGLYNATISEENKAQNQAYRGFVVNFEFQDANIYIDQVHKQVICEVTYTNDLLQKKNNKDGAQIGVVNHTTIQLAYTKLNGKYLINQMSTILLTDSANPSEETESYGAIAPSNTKD
>NZ_ANEC01000021.1|WP_000606554.1|44247_44520_-|hypothetical-protein
MINEEHMNQTNSSKKRRQKSTQERLDDKIKQLEKAQESQDALQKKIKTLKDDIASLEGKRQQEIMAEYGIDLHGLEAILATHKEERGGEG
>NZ_ANEC01000021.1|WP_000488485.1|43465_44248_-|hypothetical-protein
MFRIQNQSDGKEQEFQNLAALLYALEGEEKRCLQLNMRATFYLFHLDKNEEVLESMELTIPAQEDKEVQELIGEFGRKGEAKKPFWKRSESKQQPQAINSSNSNDSQSKTGVSKLVKGLMWLLPMVLSVVSIYLSLETLQLIKTQPQVTPKVETVVTNQKADVFCRYFISSYFSQSPNLGDYLSEKLSIDDLKTDKVTPVSVLLESQEIKGDTTLVTYVVNIKEAQDHVSSKRLTLAVRADKKAQYGYLVIKKLRLTAYP
>NZ_ANEC01000021.1|WP_000371901.1|42952_43444_-|DUF3801-domain-containing-protein
MDQERVMEKGSRVTLETGKHLLQFLAYAVSQGAKIYTEHKQSGEMSWKDFNQLPRTKDHIDFEEAEVNLEKLRKELKKSGVNFHFKKNGDGTKQVWFEAINQQVIQEALRKINQEIVSNPKEALDKYMKKPDELTPKQQIEKLKKTSKKSTEAVKTKKKGKDI
>NZ_ANEC01000021.1|WP_000129105.1|55274_55574_-|hypothetical-protein
MTDETKKVYLRDLRNLGKQGGATARLEDGTELFLKPDYAVRTAKGYVDGIPRDVEFHLTYRSIFNQIRTIKKDGHLVARKERSPSGLVLQLTGKGYKRP
>NZ_ANEC01000021.1|WP_000208122.1|55956_56154_-|helix-turn-helix-transcriptional-regulator
MTTITQNRVKELRKQAGLSQQALADQIGVMRKTISHWELGNHRISTDNAKKLSQFFQVSIDDLLE
>NZ_ANEC01000021.1|WP_000938679.1|56150_56336_-|hypothetical-protein
MLQDEFRPIPHKVLTIGRSPKESVIAIPKAIFNLPPEEKAQALKELEEDMEQHKAKGGDST
>NZ_ANEC01000021.1|WP_000822468.1|56337_57363_-|replication-initiator-protein-A
MKRISARQVQSSERFYRIPKIFVESPFYKSMSTDAKFTYAILKDRFELSLKNNWIDKNGDVYLIYTVTELQEILGYGNKKVIKLKKELQEYGLLEEVRQGLNKPNLLYLGNVDYQNVPTEEIHSKPSSVAEVSKQHFQKNQGNVKMTRQKMSKRHANDTENSETELSNDTNRYQGDASLDILSASDSFQMGQHGFLSSKTINRLSLFGKEAKLLENKIYQAKRQVEKDYSHLLQHQEIIYGEVWSQELEREVDKLIFKIKTGENEGKAIKNIPGYFYKMMVRFWKMALLIEKEQGFIALSNQSDYAKSFPEECPSLISYYYPNKLSEKELNQYLTTLRMEE
>NZ_ANEC01000021.1|WP_000447421.1|57635_58079_-|hypothetical-protein
METGIKKGHFKESVEKRIHSQHMRIEPNISNRSTRIRDISYDQSKKLYRVTIVRNGIRYGGKHFKKLGEAQKYKKQLLEDIKRKIKESQMSQTAIAQLTKNMMVFNVVVLSLGYFNVIPYKWSLILWGSAVFTAIFNEISKQIPDEK
>NZ_ANEC01000021.1|WP_000191926.1|58344_58602_-|DUF3850-domain-containing-protein
MTQHLLNCYPEYFEAIMDGTKTFECRYNDRDFKVGDELLLREYDPQKGYTYRCIVRKITYILSDFIGLKDGYVILGVTNEPIDYF
>NZ_ANEC01000021.1|WP_001282475.1|58785_59157_-|hypothetical-protein
MSDNIEIIMDIETLDIFEVIDLDEEKGVTVSDSETFPKEEKASPYDDLNRIWLRNGYYYKPSSLLWEVIENGIIHDLSSRNKHGTYPYYQNLRDGTWGHVKQLTQEEALWLTLELNPDLMNYV
>NZ_ANEC01000021.1|WP_000481327.1|59270_60254_-|GMP-reductase
MFNDIPVFDYEDIQLIPNKCIISSRSQADTSVKLGNYTFKLPVIPANMQTIIDEEVAETLACEGYFYIMHRFNEEERKPFIKRMHDKGLIASISVGVKDYEYDFVTSLKEDAPEFITIDIAHGHSNSVIEMIQHIKQELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCSKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHLESPGKLVEVDGQQFKEYYGSASEYQKGEHKNVEGKKILLPVKGRLEDTLTEMQQDLQSSISYAGGKELDSLRHVDYVIVKNSIWNGDSI
>NZ_ANEC01000021.1|WP_000162146.1|60456_61797_-|MFS-transporter
MTKKGWRIMPAIITTAILGFSGILIETSMNVTFPLLMKEFGVNPAVIQWVTTGNLLAVAVTVPLSAFMIKNLSERQIFTLANVLFLSGVLIDSFAPNLAILLVGRVLQGVGTGLALPLLFHIILTQIPMERRGLMMGVAAMVTLLAPAVGPTYGGVISGMLGWKMIFMLLAPILIISTFIGLASIPKRQVRINDKLNFPAFVSLGIGLATLLLAIEKMSIFYLLVAIVSFVIFYYLNKQLEFLNLNVFKDKDFSILLYGVLAFQMIPLALSFLLPNLLQLVLHQTSTKAGLFMFPGAIAVVFLSPFAGYLLDKIGAFKPIMIGISLSLIGLIGTAIFIPAKFVVVLLAFDILTKIGMGIGASNMVTTALTKLKPAQSADGNSILNTLQQFAGAFATAVASQIFTIGQVAIPKNGAIIGSQFAVLFVIIVVILAIVGLTYLRKRKAI
>NZ_ANEC01000021.1|WP_001867987.1|62067_62760_+|hypothetical-protein
MLIPKKIVAFASNESENNFFITLKTYFNYLFSIQIITDISTLNHADFDGSFAFHDIETSIPHLVIDSNYLAISQTNSKTEANDIKTFSELSKTMTEFHYMLNFDLFNHLPYRFRLHNKDGQTIYSNHKPEDPFDIYPEEEYPIDKWVQNSLIEKKAKELHLLLPGASQDYILVQSYKRLENDSGQLVGYIEHVHNIKPLLEGYLKESGQAIVGWSDVTSGASISNDDFEL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12817 : 21808

Bacillus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000222544.1\|12817_14536_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.4e-278	84.8
WP_000746859.1\|14599_14797_-	hypothetical protein	NA	NA	NA	NA
WP_000647638.1\|14810_16544_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.1e-50	31.0
WP_000826946.1\|16544_18266_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-40	26.7
WP_000472259.1\|18277_18880_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.1e-20	40.1
WP_000968655.1\|18881_19859_-	nucleoid-associated protein	NA	NA	NA	NA
WP_000575545.1\|19863_21120_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	7.8e-93	51.7
WP_000998735.1\|21211_21808_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	1.1e-15	29.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_ANEC01000016

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

40028 : 47232

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000706188.1\|40028_41273_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.7e-87	41.3
WP_000217754.1\|41274_42558_+	insulinase family protein	A0A2K9V7S4	Bandra_megavirus	1.3e-21	33.3
WP_000976003.1\|42680_43223_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000181757.1\|43222_44062_+	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
WP_000510606.1\|44037_44880_+	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	2.5e-18	25.5
WP_000359358.1\|44872_45667_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000029066.1\|45882_46422_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	5.8e-21	42.2
WP_001042655.1\|46527_47232_+	transglycosylase SLT domain-containing protein	A0A2H4J6C5	uncultured_Caudovirales_phage	4.2e-27	56.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_ANEC01000030

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_ANEC01000030_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANEC01000030_1

263368-264081

Orphan

Consensus_repeat	Method
AGTGCNTCNACGTCAGCN	CRT

16 spacers

The CRISPR arrays of NZ_ANEC01000030_1

>merge|NZ_ANEC01000030|1|263368-264081|CRT
AGTGCCTCGACGTCAACAAGTACTAGCGCTTCCACGTCAGCAAGTACCAGTGCATCCACATCAGCAAGTATGAGCGCATCCACGTCAGCAAGTACCAGTGCATCCACGTCAGCAAGTATGAGCGCCTCCACAAGTGCAAGTATCAGTGCATCCACGTCAGCAAGTATGAGCGCTTCCACAAGTGCAAGTACCAGTGCATCGACGTCAGCAAGTACTAGCGCCTCAATGAGTGCATCGACGTCAGCCAGCACCAGTGCTTCCACAAGTGCAAGTACTAGCGCCTCAATGAGTGCATCGACATCAGCAAGTACCAGCGCTTCCACAAGTGCAAGTACGAGTGCTTCCACATCAGCAAGTACTAGCGCCTCAACATCGGCAAGTACAAGTTCTTCCACAAGTGCAAGTACCAGTGCATCGACATCAGCCAGCACTAGCGCCTCAATGAGTGCCTCGACGTCAGCCAGCACAAGTGCTTCCATGAGTGCGTCGACGTTAGCCAGCACTAGCGCCTCAACGAGTGCGTCAATGTCAGCCAGCACAAGTTCTTCAACAAGTGCCTCGATGTCAGCCAGCACTAGCGCTTCAATGAGTGCGTCGACGTCAGCCAGCACCAGCGCTTCAACGAGTGCGTCAATGTCAGCCAGCACTAGCGCTTCAATGAGTGCCACGACGTCAGCCAGCACCAGCGTCTCAACGAGTGCATCGACATCAGCA

>NZ_ANEC01000030|1|1|263368-264081|CRT
AGTGCCTCGACGTCAACA	AGTACTAGCGCTTCCACGTCAGCAAGTACC
AGTGCATCCACATCAGCA	AGTATGAGCGCATCCACGTCAGCAAGTACC
AGTGCATCCACGTCAGCA	AGTATGAGCGCCTCCACAAGTGCAAGTATC
AGTGCATCCACGTCAGCA	AGTATGAGCGCTTCCACAAGTGCAAGTACC
AGTGCATCGACGTCAGCA	AGTACTAGCGCCTCAATG
AGTGCATCGACGTCAGCC	AGCACCAGTGCTTCCACAAGTGCAAGTACTAGCGCCTCAATG
AGTGCATCGACATCAGCA	AGTACCAGCGCTTCCACAAGTGCAAGTACG
AGTGCTTCCACATCAGCA	AGTACTAGCGCCTCAACATCGGCAAGTACAAGTTCTTCCACAAGTGCAAGTACC
AGTGCATCGACATCAGCC	AGCACTAGCGCCTCAATG
AGTGCCTCGACGTCAGCC	AGCACAAGTGCTTCCATG
AGTGCGTCGACGTTAGCC	AGCACTAGCGCCTCAACG
AGTGCGTCAATGTCAGCC	AGCACAAGTTCTTCAACA
AGTGCCTCGATGTCAGCC	AGCACTAGCGCTTCAATG
AGTGCGTCGACGTCAGCC	AGCACCAGCGCTTCAACG
AGTGCGTCAATGTCAGCC	AGCACTAGCGCTTCAATG
AGTGCCACGACGTCAGCC	AGCACCAGCGTCTCAACG
AGTGCATCGACATCAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANEC01000030.1\|WP_001865283.1\|266815_268057_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|133037
NZ_ANEC01000030.1\|WP_000104405.1\|275815_276808_+\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_ANEC01000030.1\|WP_075316641.1\|274280_275819_+\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_ANEC01000030.1\|WP_000795050.1\|268046_269231_+\|glycosyl-transferase-family-8	unknown	unknown	gnl\|CDD\|133037
NZ_ANEC01000030.1\|WP_000681005.1\|253668_255852_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|270337
NZ_ANEC01000030.1\|WP_001263852.1\|270159_271356_+\|SP_1767-family-glycosyltransferase	unknown	unknown	gnl\|CDD\|163440
NZ_ANEC01000030.1\|WP_001263776.1\|264597_265605_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|236626
NZ_ANEC01000030.1\|WP_000567072.1\|257015_259007_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_ANEC01000030.1\|WP_000818887.1\|252928_253669_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_ANEC01000030.1\|WP_079266267.1\|269211_270099_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_ANEC01000030.1\|WP_000772257.1\|271479_272709_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_ANEC01000030.1\|WP_000502594.1\|252179_252338_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000030.1\|WP_000571941.1\|259103_260600_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|285470
NZ_ANEC01000030.1\|WP_000244039.1\|249232_250474_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_ANEC01000030.1\|WP_000863865.1\|250651_250780_+\|DUF4044-domain-containing-protein	unknown	unknown	gnl\|CDD\|338651
NZ_ANEC01000030.1\|WP_000468350.1\|272708_274253_+\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598
NZ_ANEC01000030.1\|WP_001042316.1\|256034_256955_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_ANEC01000030.1\|WP_000751408.1\|265613_266819_+\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|133037
NZ_ANEC01000030.1\|WP_000061665.1\|250840_252154_+\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_ANEC01000030.1\|WP_000656279.1\|252429_252780_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_ANEC01000030.1\|WP_001865283.1\|266815_268057_+\|glycosyl-transferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	4.60076e-75
NZ_ANEC01000030.1\|WP_000104405.1\|275815_276808_+\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	7.04012e-61
NZ_ANEC01000030.1\|WP_075316641.1\|274280_275819_+\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_ANEC01000030.1\|WP_000795050.1\|268046_269231_+\|glycosyl-transferase-family-8	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.05657e-73
NZ_ANEC01000030.1\|WP_000681005.1\|253668_255852_-\|ABC-transporter-permease-subunit	gnl\|CDD\|270337	cd13619, PBP2_GlnP, Glutamine-binding domain of ABC transporter, a member of the type 2 periplasmic binding fold protein superfamily. Periplasmic glutamine binding domain GlnP serves as an initial receptor in the ABC transport of glutamine in eubacteria. GlnP belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.85761e-106
NZ_ANEC01000030.1\|WP_001263852.1\|270159_271356_+\|SP_1767-family-glycosyltransferase	gnl\|CDD\|163440	TIGR03728, glyco_access_1, glycosyltransferase, SP_1767 family. Members of this protein family are putative glycosyltransferases. Some members are found close to genes for the accessory secretory (SecA2) system, and are suggested by Partial Phylogenetic Profiling to correlate with SecA2 systems. Glycosylation, therefore, may occur in the cytosol prior to secretion.	9.90538e-161
NZ_ANEC01000030.1\|WP_001263776.1\|264597_265605_+\|sugar-transferase	gnl\|CDD\|236626	PRK09814, PRK09814, sugar transferase.	1.32907e-150
NZ_ANEC01000030.1\|WP_000567072.1\|257015_259007_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_ANEC01000030.1\|WP_000818887.1\|252928_253669_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.4733e-157
NZ_ANEC01000030.1\|WP_079266267.1\|269211_270099_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	7.34643e-33
NZ_ANEC01000030.1\|WP_000772257.1\|271479_272709_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	1.15376e-161
NZ_ANEC01000030.1\|WP_000571941.1\|259103_260600_-\|transcriptional-regulator	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	3.82119e-24
NZ_ANEC01000030.1\|WP_000244039.1\|249232_250474_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_ANEC01000030.1\|WP_000863865.1\|250651_250780_+\|DUF4044-domain-containing-protein	gnl\|CDD\|338651	pfam13253, DUF4044, Protein of unknown function (DUF4044). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 56 amino acids in length. There is a single completely conserved residue M that may be functionally important.	1.85741e-06
NZ_ANEC01000030.1\|WP_000468350.1\|272708_274253_+\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	0
NZ_ANEC01000030.1\|WP_001042316.1\|256034_256955_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.55469e-11
NZ_ANEC01000030.1\|WP_000751408.1\|265613_266819_+\|glycosyl-transferase	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	2.10249e-70
NZ_ANEC01000030.1\|WP_000061665.1\|250840_252154_+\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0

>NZ_ANEC01000030.1|WP_000571941.1|259103_260600_-|transcriptional-regulator
MIENFLEKNILNKVKLLTLCYDTPSLSLDTACNRLHLSPVELKNYCHKLNVLFGHKLSIHIQKERILCKLNKLTQEDALKIVYNESNTLQLLKFLIDDSSDKKSLVAFGNDLFLSRSSVYRLRENLIPLIKDLGLSLSKNTIVGDEYRIRYLIAYLTTKFGIKIYDLSALDIKIIRQFLFESGTNIRPTTHLSDIFIFFDTLFILTWKRHHHKVKIPNSKLFSSLKKIFIYEELNTCVKSIVQPYFNVIFNSEDMDYIFLIYLTSANSFAAQKWTETHVDEVLAIFKSLPKFQMLLQPLKEALPYSDTYYDELVKVTIYFSRNFIVGLNQLIPETLSFPSTFYPGNNPKLISIIEPIVTHWLTEIGESKFKKTHFFLLCAHLERVIKNSMPPINIVLLTTDFINNEILKDYILQSLSTDKIRFHSYYLLTDNISQISTLKPDLIITNRKLFTYVTKELATNSLVAHIDYNDTPSQISNIQTIISNIKEEKYRKIFDKI
>NZ_ANEC01000030.1|WP_000567072.1|257015_259007_+|excinuclease-ABC-subunit-B
MIDRKDTNRFKLVSKYSPSGDQPQAIETLVDNIEGGEKAQILKGATGTGKTYTMSQVIAQVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGQEISRDQLLNNLVDIQFERNDIDFQRGKFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGRVLGEVEHLAIFPATHFMTNDEHMEEAISKIQAEMENQVELFEKEGKLIEAQRIRQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYEMEQTDTVVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRTEKGERTFITTLTKRMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSNGHVIMYADKITDSMQRAMDETARRRRLQMDYNEKHGIVPQTIKKEIRDLIAITKSNDSDKPEKVVDYSSLSKKERQAEIKALQQQMQEAAELLDFELAAQIRDVILELKAID
>NZ_ANEC01000030.1|WP_001042316.1|256034_256955_+|CPBP-family-intramembrane-metalloprotease
MNKRILNSQFAVYKNWPSWLLLLFACFMVYLFFFVGLTLGGVGIVLVSSVLYKFSSYTFFEFINLFNNIYGELGTFSFSAFLLLIWVKFVEKRPFSELGFSTKFKRTLWSLIKGWSIGFILFSISVITAYILGGLDFHSYDVSKATIFYVVTLLPFWLIQSGTEELLTRGWLLPLINHRFHLAVAIGVSSTLFGILHLVNAHVTFLSIVSIICSGVLMSLYMIKSGNIWSVAALHGAWNFSQGNLYGIAVSGQKAGASLLHFTVKENAPDWISGGAFGIEGSLISIFVLLAAIIYLLWLIKTEETD
>NZ_ANEC01000030.1|WP_000681005.1|253668_255852_-|ABC-transporter-permease-subunit
MKHKLKAFTLALLSIFFVFGGKVSAETVNIVSDTAYAPFEFKDSDQTYKGIDVDIVNEVAKRAGWNVNMTYPGFDAAVNAVQSGQADALMAGTTVTEARKKVFNFSDTYYDTSVILYTKNNNKVTNYKQLKGKVVGVKNGTAAQSFLEENKSKYGYKVKTFDTSDLMNNSLDSGSIYAAMDDQPVVQFAINQGKAYAINMEGEAVGSFAFAVKKGSGHDNLIKEFNTAFAQMKSDGTYNDIMDKWLGKDATKTSGKATGNANEKATPVKPSYKIVSDSSFAPFEYQNGKGKYTGFDMELIKKIAKQQGFKLDISNPGFDAALNAVQSGQADGVIAGATITEARQKIFDFSDPYYTSSVILAVKKGSNVKSYQDLKGKTVGAKNGTASYTWLSDHADKYNYHVKAFDEASTMYDSMNSGSIDALMDDEAVLAYAINQGRKFETPIKGEKSGDIGFAVKKGANPELIKMFNNGLASLKKSGEYDKLVKKYLSTASTSSNDKAAKPVDESTILGLISNNYKQLLSGIGTTLSLTLISFAIAMVIGIIFGMMSVSPSNTLRTISMIFVDIVRGIPLMIVAAFIFWGIPNLIESITGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPSGQMEASRSLGISYGKTMQKVILPQAVRLMLPNFINQFVISLKDTTIVSAIGLVELFQTGKIIIARNYQSFRMYAILAIMYLVIITLLTRLAKRLEKRLK
>NZ_ANEC01000030.1|WP_000818887.1|252928_253669_-|amino-acid-ABC-transporter-ATP-binding-protein
MAELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGKSTFLRTLNLLESITSGKVVVDGFELSNPKTDIDKARENIGMVFQHFNLFPHMSVLENITFAPIELGKESKEAAEKHGMELLEKVGLADKANAKPDSLSGGQKQRVAIARSLAMNPDILLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGRFLEDGTPEQIFDTPQHPRLQDFLNKVLNV
>NZ_ANEC01000030.1|WP_000656279.1|252429_252780_-|hypothetical-protein
MKDYINRILHFIKEHMTYHVNFIDDFLDIKWEKVSNIHLRFWTTIIAYLVIFILSISTVILNLVLLFQGFLTQNPIIYLLFFITLVCAFYFAYKFITYTPTIVKNALQYIKKLKNV
>NZ_ANEC01000030.1|WP_000502594.1|252179_252338_+|hypothetical-protein
MGDKPISFRDKDGNFVSAADVWNAEKLEELFNTLNPNRKLRLEREKLAKEKG
>NZ_ANEC01000030.1|WP_000061665.1|250840_252154_+|GTPase-ObgE
MSMFLDTAKISVKAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVNEGLRTLMDFRYNRNFKAKAGEKGMTKGMHGRGAEDLIVSLPPGTTVRDATTGKVITDLVEHDQEFVVARGGRGGRGNIRFATPRNPAPEIAENGEPGEERELQLELKILADVGLVGFPSVGKSTLLSVVSAAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYDDYVSINNELETYNLRLMERPQIIVANKMDMPDSEENLAAFKEKLAANYDEFDDMPMIFPISSLAHQGLENLMDATAELLANTEEFLLYDETDMQEDEAYYGFNEDERPFEITRDDDATWVLYGDKLEKLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGNFEFEFVD
>NZ_ANEC01000030.1|WP_000863865.1|250651_250780_+|DUF4044-domain-containing-protein
MAFGDNGQRKKTGFEKLTLFVVILMVLVTVGGLVFGAISAIM
>NZ_ANEC01000030.1|WP_000244039.1|249232_250474_-|aminopeptidase
MVLQDFDNLLKKYAQLIISKGLNVQKGHTLALTIDVEQVHLARLLTEAAYEKGASEVIVDYTDDFITRQRLLHASDEVLTNVPQYTVDKSLALLNKKASRLVVKSSNPNAFATVDPKRLSETTRATAIALEEQSRAIQANKVSWNVAAAAGREWAALVFPELKTSDQQVDALWDTIFKLNRIYEDDPIAAWDAHEAKLLEKATRLNQEQFDALHYTAPGTDLTLGMPKNHIWEAAGSLNAQGETFIANMPTEEIFSAPDYRRADGYVTSTKPLSYAGVIIENMTFTFKDGKIINVTAEKGQETVQRLIEENDGARSLGEVALVPHKTPISLSGLIFFNTLFDENASNHLAIGSAYAFNVEGGTEMTSQELDEAGLNRSSTHVDFMIGSEQMDIDGIRADGTAVPIFRNGEWAI
>NZ_ANEC01000030.1|WP_001263776.1|264597_265605_+|sugar-transferase
MRVHITSIYGQSPRSIALISQKLVKDVGRQLGYDEMGIYFYNDHAETHGERSTRMDGIIAGLGRGDIVVFQVPTWNSTEFDELFLDKLQAYGARIITFVHDIVPLMFESNFYLLDRVIDMYNRSDVVILPTKAMHDYLIEKGMTTSKVLYQEVWDHPVNIDLPRPECQKVLSFAGDIQRFPFVNDWKENIPLIYYGDGSRLNSEANVHAQGWKDDVELMLSLSKRGGFGLCWSEDREELVERRYSRMNASYKLSTFLAAGLPIIANHDISSRDFIKQHGLGFTVETLEEAVEKINNMEKETYDSYVENVEKIATLLRNGYITKKLLIDAVHMLYR
>NZ_ANEC01000030.1|WP_000751408.1|265613_266819_+|glycosyl-transferase
MKKTIVLGADFQYRDQVMTTIKSIVSHNQHLTIYIINTDFPVEWFNILNHSLEQFDCRVKNIPISSDVFEGIPTLSHISVAGFFRWFIPIHLEEEIVLYLDSDVIVRGSLDPLFDINLEENLLGAVADHFSTLYYGDTAPVSFNSGVMLINNSLWKKEEIYNSLMRIADKGSAVGVGDQEYLNILTQNRWIDIGKQYNVQIGQDVNINAYGRPDLYHFYDDCEPVIVHYNSQDKPWNKYSQSRYRSEWWYYFGLEWSVIYAQQQKNLNRLTGKTLNLFTLTASDTLEHIEVLAKALPDYQFHIAARSDISEKLANLETYSNIKVYKLVINPILEELIRNCDVYLDINHSYEVEGILDKIKEENKPILAFDSTAHTTKNIEVISETMPELMVKRIREVGPLR
>NZ_ANEC01000030.1|WP_001865283.1|266815_268057_+|glycosyl-transferase
MKNRKAIALAADFGYQEQVKTIIKSICFHNQFIDFYILNDDFPVEWFQMMEYHLSKMDCTISNTKIFNEEIKHFKFQKPMPYPTYFRYFIPEVIHEDKVLYLDCDMIITSDLTSIFTLDISKYGVAAVRDDLLEEYDGKEDYFNSGLLLINNIFWREQGISQRLLDYTRENQGALQYHDQDVLNDVLCDNWLELDETYNYHTGADMLYNLFQQSERQLNRRKDLPKVIHYTATKPWKYLETSVRWRDIWWEYNRLEWRDIFTRWQVNDGVDVSLKKVLQPIHRAFIFTYSDSIEGIERLAKDLPNWQFHIAAYTQISEKLKQLEMHSNIKLYPLVYRFKLNELVENSDIYLDINHGDADTQVLEQVKKLGKDILSLSTTYHGQGKQFERVTDIIDYLKNERFKEHIRKEYCEK
>NZ_ANEC01000030.1|WP_000795050.1|268046_269231_+|glycosyl-transferase-family-8
MKNNVICLAGDNKSLNQIQTVIKSILCHNDRVSIYILNQDIASEWFRNIQRRLLNSHSCIFDIKLFDDTFKEFKTPRAHITYMAYARYYIPQLIDAEKVLYLDIDTLVVDNLDKLFEIELGDYPIAAILDGDGIHFNSGVMLINSLYWMRYRVTEKLLEITERELDNGIFGDQGVLNLLFDNNWLKLEDKYNAQVGNDLGAFYENWQGYFDRNFESPTIIHYCTHDKPWNTFSSSRFRETWWQYEQLDWNEVFNFETYLLPEPTFEKHFFTFTTSVDLLYIEELVELFPNSCFHIAAWTSFGPRLLKLATNSNVRLYPSITSPLFEQLMTKANYYLDISTSWKEIQFCQKAIEKSIPILSFNEAVTFEYRELSHCFINLEDMRQFLCKNGGNSD
>NZ_ANEC01000030.1|WP_079266267.1|269211_270099_+|glycosyltransferase-family-2-protein
MEAIVTDKLVSVIIPVYNAAPYLEGCVNTILGQTYQVFEILLIDDGSTDTSASICDQLYLRDNRIRVFHIENGGASKARNFGLARISPESQFVTFVDSDDWVKENYLEVLLAQQEKYNADIVISNYYIYRETEDIFGYYITDKDFVIEEISAQTAIDRQVHWHLNSSVFIVIWGKLYRRELFDTITFPIDKVFEDELVSVLLFIKSKKTILVNGSYYGYRIRPNSIMTSAFSSKIAEDLIYIFDSKLSEIILSGLDSTATVERYFWLMRDYKQRLEQENLQKTIIYKVISNRLSR
>NZ_ANEC01000030.1|WP_001263852.1|270159_271356_+|SP_1767-family-glycosyltransferase
MRVIKVKTISETLDYISKHTASVARFGDGEIDIIAGNSIPYQVYDSELAKRLERLLNRQSNEKLVICVSDVFDNLGRYNDFSQQFWRDHLYQYNDLYQKNCQAEWYGSTFISRPYMDLLDKSLSVTYFEQLKALWKNKDILIVEGETSRSGVGNDLFNDANTISRIICPSKDAFSSFYEIKETILEHSRGKLILLMLGPTAKLLAEDLSQLGHQAIDLGHIDSEYEWFKMGAVSKVKLSHKHTAEHNFDEDITLIEDNSYENQIVSKIGTSDRQYALTVTLTDDIWELEHLLQRCPNTNFHIAAPVYCSDRLKQLVGYPNYYLHEAITEEQFEVLLLNSDIYLDINHGEEVWNVVDRCITEGKTIYGIRRARKDNQYISFERTMDDFEYLCDTIKQNR
>NZ_ANEC01000030.1|WP_000772257.1|271479_272709_+|accessory-Sec-system-protein-translocase-subunit-SecY2
MKLLYIFEKNIILRKILITFSLIIIFLLGRYVPIPGVLISAYKGQDNNFATLYSTVTGGNLSQVGVFSLGIGPMMTTMILLRLFTIGKYSSGVSQKVQQFRQNVVMLVIAIIQGLAIAISFQYHNGFSLTKLLLATMILVTGAYIISWIGNLNAEYGFGGMTILVVVGMLVGQFNNIPLIFELFQDGYQLAIILFLLWTLVAMYLMITFERSEYRIPVMRTSIHNRLVDDAYMPIKVNASGGMAFMYVYTLLMFPQYIIILLRSIFPTNPDITSYNDYFSLSSIQGVVIYMILMLVLSVAFTFVNIDPTKISEAMRESGDFIPNYRPGKETQSYLSKICYLFGTFSGFFMAFLGGVPLLFALGNDDLRTVSSMTGIFMMITGMSFMILDEFQVIRIRKQYTSVFENEEN
>NZ_ANEC01000030.1|WP_000468350.1|272708_274253_+|accessory-Sec-system-protein-Asp1
MFHFIPSWYNENRTWYDNNYLWYFKPTNVGFDDTINQMKMFDYAGKESRLVVLNYMPNLRYYLHRYDLLESGYYSVFDDIQEIGNVRQQMIDFRQLNWPEGVDFTYTPFIVLVKKSGDLIAKVQFGEEGNLTHIDYFANEQIAKKYLFDDRGFLSSILYYDNGGEAYQDYLAPSGERIMREYLREGDHHVEINPKKAIHFLKLSYSDIEELIREKYLTYLHKEVSKSDTIIVSFNQVHNAFIVGNTSKGNLILSVFSERNNAHNVLEDYSSLSRANAIICDRLDIAAQLKEKIDKPVVHVSPFDTRLALGKSNQVRDLEIYFVVDRLSHKELQKSLTSLYKVMLKNNDIKVTFVSYEREFESRQLTYDYLKEATKVFDQKFFSLSDDDANQVLMQSDEVEKEKTRLSFTHPLSETDIINRLEYVRLIIDISKIPDLYTQIAGISSGIPQINTILTEFVEHRKNGYVIEEIQELEKAIPYYCEQLTNWNRSLIYSIDKINDYTGGQLVERIINSY
>NZ_ANEC01000030.1|WP_075316641.1|274280_275819_+|accessory-Sec-system-protein-Asp2
MLQVGEENWATKENIPNNMEWLFIKPDQISDFVTTENNYLTSSKLLQKLPRKISALLLTEQTYGPELSSLSSFFEVYEVFYPKDKHATGITEEFLRSKMAQRYDSSSPDQLIRQFYKGLFIGQYGEKLQVSQIQIRNDFEGVVNYQGNNYLELEGQFGENYSFLLNFAYNIPFSSDFYNELFLEHIIEGDIDIRLVISLIVDGSVDDIAKEWYFEKEDLNQLISLESDISGSLAVKLFAKGKGIVKLGPLHRRNGRGGLGTFLLGGERHIDAIGHEFMTYFDPVDFKPPLTVYFSGFRSAEGFEGFWMMKSMKTPFMLICDPRLQGGAFYIGSKEYEQKIVDAIQEKLAFLNFSSDQLILSGLSMGTYGATYHGAKLNPHAIIIGKPIFNLGTVAQRERLERPDGFATSLDIQLLNQGDLTSSSSEKLNNYFWKSIEEGDFSNTTFALAYMKNDDYDATAFSDLLQYFRGKKHKILGRGWDGRHGDCSAEVGAWFTSQYRRMLSNDFGRKEE
>NZ_ANEC01000030.1|WP_000104405.1|275815_276808_+|accessory-Sec-system-protein-Asp3
MSTISYIYWDDFSRFSYNFGTKLQFLGKSVCFENPLAPSSTNLYTWSSQTNYQSKRISPNLPLLRKGTRYSLSLNAELDLVSSLFVRIEFYNRFNESVGFELLKKDSIIFIYPKEAYTYTISLINAGCSDFTFHYLKLEEVTDSVIQEKNLSTEFTIEEHQDVLNLLLVEKKDSVYINKIESISQLQQKVELVSNPSLNSDSLILPKLEKGLEDALKVFPNIKINVIAYGTQGNFAALYYAKKFPRITAYINDCFAPFGILLKSLPHLTAKQQIFLREVWDTRETSPNVKHYGLVSENSSLNLVSMILSGNEHLPYLTLLKKQDDNYDSL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_ANEC01000030_1	1.11\|263866\|18\|NZ_ANEC01000030\|CRT	263866-263883	18	NZ_ANEC01000030.1	263194-263211	0	1.0
NZ_ANEC01000030_1	1.11\|263866\|18\|NZ_ANEC01000030\|CRT	263866-263883	18	NZ_ANEC01000030.1	263158-263175	1	0.944
NZ_ANEC01000030_1	1.12\|263902\|18\|NZ_ANEC01000030\|CRT	263902-263919	18	NZ_ANEC01000030.1	263062-263079	1	0.944
NZ_ANEC01000030_1	1.14\|263974\|18\|NZ_ANEC01000030\|CRT	263974-263991	18	NZ_ANEC01000030.1	263158-263175	1	0.944
NZ_ANEC01000030_1	1.16\|264046\|18\|NZ_ANEC01000030\|CRT	264046-264063	18	NZ_ANEC01000030.1	263158-263175	1	0.944
NZ_ANEC01000030_1	1.16\|264046\|18\|NZ_ANEC01000030\|CRT	264046-264063	18	NZ_ANEC01000030.1	263194-263211	2	0.889

1. spacer 1.11|263866|18|NZ_ANEC01000030|CRT matches to position: 263194-263211, mismatch: 0, identity: 1.0

agcactagcgcctcaacg	CRISPR spacer
agcactagcgcctcaacg	Protospacer
******************

2. spacer 1.11|263866|18|NZ_ANEC01000030|CRT matches to position: 263158-263175, mismatch: 1, identity: 0.944

agcactagcgcctcaacg	CRISPR spacer
agcaccagcgcctcaacg	Protospacer
*****.************

3. spacer 1.12|263902|18|NZ_ANEC01000030|CRT matches to position: 263062-263079, mismatch: 1, identity: 0.944

agcacaagttcttcaaca	CRISPR spacer
agcacaagtgcttcaaca	Protospacer
********* ********

4. spacer 1.14|263974|18|NZ_ANEC01000030|CRT matches to position: 263158-263175, mismatch: 1, identity: 0.944

agcaccagcgcttcaacg	CRISPR spacer
agcaccagcgcctcaacg	Protospacer
***********.******

5. spacer 1.16|264046|18|NZ_ANEC01000030|CRT matches to position: 263158-263175, mismatch: 1, identity: 0.944

agcaccagcgtctcaacg	CRISPR spacer
agcaccagcgcctcaacg	Protospacer
**********.*******

6. spacer 1.16|264046|18|NZ_ANEC01000030|CRT matches to position: 263194-263211, mismatch: 2, identity: 0.889

agcaccagcgtctcaacg	CRISPR spacer
agcactagcgcctcaacg	Protospacer
*****.****.*******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_ANEC01000030_1	1.1\|263386\|30\|NZ_ANEC01000030\|CRT	263386-263415	30	NZ_CP049605	Klebsiella pneumoniae strain Kp8701 plasmid unnamed, complete sequence	113178-113207	6	0.8
NZ_ANEC01000030_1	1.1\|263386\|30\|NZ_ANEC01000030\|CRT	263386-263415	30	NZ_CP025212	Klebsiella pneumoniae strain HZW25 plasmid unnamed1, complete sequence	55307-55336	6	0.8
NZ_ANEC01000030_1	1.1\|263386\|30\|NZ_ANEC01000030\|CRT	263386-263415	30	NZ_CP031809	Klebsiella pneumoniae strain INF206-sc-2280074 plasmid unnamed, complete sequence	63171-63200	6	0.8
NZ_ANEC01000030_1	1.1\|263386\|30\|NZ_ANEC01000030\|CRT	263386-263415	30	NZ_CP041936	Klebsiella pneumoniae strain KP14003 plasmid unnamed2, complete sequence	46656-46685	6	0.8
NZ_ANEC01000030_1	1.1\|263386\|30\|NZ_ANEC01000030\|CRT	263386-263415	30	NC_019390	Klebsiella pneumoniae plasmid pKPN_CZ, complete sequence	43635-43664	6	0.8
NZ_ANEC01000030_1	1.7\|263674\|30\|NZ_ANEC01000030\|CRT	263674-263703	30	NC_020910	Octadecabacter arcticus 238 plasmid pOA238_160, complete sequence	105422-105451	7	0.767
NZ_ANEC01000030_1	1.3\|263482\|30\|NZ_ANEC01000030\|CRT	263482-263511	30	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	1090242-1090271	8	0.733
NZ_ANEC01000030_1	1.3\|263482\|30\|NZ_ANEC01000030\|CRT	263482-263511	30	NZ_HG938357	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141b, complete sequence	80295-80324	8	0.733

1. spacer 1.1|263386|30|NZ_ANEC01000030|CRT matches to NZ_CP049605 (Klebsiella pneumoniae strain Kp8701 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

---agtactagcgcttccacgtcagcaagtacc	CRISPR spacer
ctcaggcct---gcttccacgtcagcacgtacc	Protospacer
   **  **   *************** *****

2. spacer 1.1|263386|30|NZ_ANEC01000030|CRT matches to NZ_CP025212 (Klebsiella pneumoniae strain HZW25 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

---agtactagcgcttccacgtcagcaagtacc	CRISPR spacer
ctcaggcct---gcttccacgtcagcacgtacc	Protospacer
   **  **   *************** *****

3. spacer 1.1|263386|30|NZ_ANEC01000030|CRT matches to NZ_CP031809 (Klebsiella pneumoniae strain INF206-sc-2280074 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

---agtactagcgcttccacgtcagcaagtacc	CRISPR spacer
ctcaggcct---gcttccacgtcagcacgtacc	Protospacer
   **  **   *************** *****

4. spacer 1.1|263386|30|NZ_ANEC01000030|CRT matches to NZ_CP041936 (Klebsiella pneumoniae strain KP14003 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

---agtactagcgcttccacgtcagcaagtacc	CRISPR spacer
ctcaggcct---gcttccacgtcagcacgtacc	Protospacer
   **  **   *************** *****

5. spacer 1.1|263386|30|NZ_ANEC01000030|CRT matches to NC_019390 (Klebsiella pneumoniae plasmid pKPN_CZ, complete sequence) position: , mismatch: 6, identity: 0.8

---agtactagcgcttccacgtcagcaagtacc	CRISPR spacer
ctcaggcct---gcttccacgtcagcacgtacc	Protospacer
   **  **   *************** *****

6. spacer 1.7|263674|30|NZ_ANEC01000030|CRT matches to NC_020910 (Octadecabacter arcticus 238 plasmid pOA238_160, complete sequence) position: , mismatch: 7, identity: 0.767

agtaccagcgcttccacaagtgcaagtacg	CRISPR spacer
gattccaacgtttccacaagtgcaagttct	Protospacer
..* ***.**.**************** *

7. spacer 1.3|263482|30|NZ_ANEC01000030|CRT matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 8, identity: 0.733

agtatgagcgcctccacaagtgcaagtatc	CRISPR spacer
aacctgagcgcctcctcaagtgcaaagagg	Protospacer
*.. *********** *********. *

8. spacer 1.3|263482|30|NZ_ANEC01000030|CRT matches to NZ_HG938357 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141b, complete sequence) position: , mismatch: 8, identity: 0.733

agtatgagcgcctccacaagtgcaagtatc	CRISPR spacer
aacctgagcgcctcctcaagtgcaaagagg	Protospacer
*.. *********** *********. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

162308 : 173041

Streptococcus_phage(84.62%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017646936.1\|162308_163073_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.4e-14	24.3
WP_000178150.1\|163072_163783_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-13	29.1
WP_001144242.1\|163801_164461_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.5
WP_000715592.1\|164549_165185_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_000364568.1\|165204_166068_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.5e-74	50.0
WP_000358198.1\|166098_166425_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_001867099.1\|166430_167294_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.1e-109	70.4
WP_079254671.1\|167269_167431_-	hypothetical protein	NA	NA	NA	NA
WP_001868293.1\|167415_167520_+	hypothetical protein	NA	NA	NA	NA
WP_000603271.1\|167563_168199_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_000158397.1\|168331_169423_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.9e-165	78.0
WP_001198082.1\|169491_170040_+	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	1.4e-54	57.9
WP_000232154.1\|170101_171283_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	9.1e-168	75.3
WP_000966769.1\|171338_171815_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.6e-38	50.9
WP_000287943.1\|171816_172173_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000767486.1\|172213_173041_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.1e-124	78.0

DBSCAN-SWA_2

349122 : 359394

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000721268.1\|349122_351267_-	LTA synthase family protein	W6LM83	Streptococcus_phage	6.3e-260	67.5
WP_001037596.1\|351401_352559_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.3e-139	66.0
WP_000707048.1\|352558_353236_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	5.3e-88	68.4
WP_001195736.1\|353329_354397_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269901.1\|354397_355564_+	chorismate synthase	A0A291AU41	Pandoravirus	9.3e-40	34.1
WP_000024620.1\|355647_355983_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	8.9e-20	39.4
WP_000043887.1\|356157_357507_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-32	25.5
WP_000033715.1\|357549_358002_-	hypothetical protein	NA	NA	NA	NA
WP_000638889.1\|358248_359394_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	4.3e-29	28.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_ANEC01000025

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

42865 : 50852

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000783409.1\|42865_44170_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	9.2e-12	34.2
WP_001045908.1\|44316_45216_-	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000197236.1\|45408_46959_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_000183891.1\|46977_47598_-	hypothetical protein	NA	NA	NA	NA
WP_000686116.1\|47616_48180_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.8e-25	35.6
WP_001291337.1\|48347_49370_-	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	1.2e-62	42.4
WP_000220683.1\|49397_50852_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-53	32.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_ANEC01000008

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

179 : 37153

Streptococcus_phage(72.5%)

portal,terminase,tail,head,holin,integrase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000236382.1\|179_899_-	CHAP domain-containing protein	A0A1U9WRD0	Streptococcus_virus	7.2e-59	70.3
WP_001001965.1\|900_1236_-\|holin	phage holin	A0A1P8VVK6	Streptococcus_phage	1.0e-36	72.1
WP_000564987.1\|1237_1534_-	hypothetical protein	Q938J6	Temperate_phage	1.2e-39	84.7
WP_001873936.1\|1767_2184_-	DUF1366 domain-containing protein	NA	NA	NA	NA
WP_000206522.1\|2355_6183_-	hypothetical protein	A7J2A7	Streptococcus_phage	2.9e-162	49.2
WP_000365119.1\|6195_7038_-	hypothetical protein	A7J2A6	Streptococcus_phage	3.4e-76	48.6
WP_017646851.1\|7050_11277_-	tape measure protein	A7J2A5	Streptococcus_phage	1.4e-21	46.6
WP_000398752.1\|11305_11536_-	hypothetical protein	A7J2A4	Streptococcus_phage	2.2e-14	59.2
WP_000424190.1\|11610_12066_-	hypothetical protein	A7J2A3	Streptococcus_phage	3.1e-55	70.9
WP_000450517.1\|12116_12749_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	2.6e-60	68.6
WP_000640604.1\|12760_13120_-	hypothetical protein	A7J2A1	Streptococcus_phage	5.6e-44	74.6
WP_000060408.1\|13123_13468_-	hypothetical protein	A7J2A0	Streptococcus_phage	6.9e-52	93.0
WP_000639437.1\|13464_13743_-	hypothetical protein	A7J299	Streptococcus_phage	4.2e-47	98.9
WP_000356705.1\|13753_14110_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	6.7e-34	62.7
WP_115357008.1\|14162_14240_+	hypothetical protein	NA	NA	NA	NA
WP_000797011.1\|15030_15600_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.5e-72	89.9
WP_001042286.1\|15742_15946_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.3e-13	53.4
WP_025194292.1\|15950_16139_-	hypothetical protein	A7J294	Streptococcus_phage	3.7e-15	77.4
WP_000358743.1\|16166_17609_-	hypothetical protein	A7J293	Streptococcus_phage	4.9e-224	77.5
WP_000462948.1\|17574_19104_-\|portal	phage portal protein	A7J292	Streptococcus_phage	6.7e-248	83.8
WP_000208745.1\|19118_20399_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	1.3e-233	94.1
WP_000041103.1\|20388_20820_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	3.9e-68	93.7
WP_000041038.1\|20940_21354_-	transcriptional regulator	A7J289	Streptococcus_phage	1.2e-42	60.6
WP_000667187.1\|21350_21851_-	DUF1642 domain-containing protein	J7KK91	Streptococcus_phage	7.3e-26	45.4
WP_000052301.1\|22011_22323_-	hypothetical protein	J7KDM7	Streptococcus_phage	4.1e-27	55.8
WP_001005355.1\|22325_22556_-	hypothetical protein	J7KK64	Streptococcus_phage	3.1e-32	100.0
WP_000687319.1\|22786_23002_-	hypothetical protein	NA	NA	NA	NA
WP_000151204.1\|22998_23397_-	RusA family crossover junction endodeoxyribonuclease	Q5YA86	Bacillus_phage	1.7e-41	61.2
WP_000666343.1\|23386_23620_-	hypothetical protein	A0A1S5SEA6	Streptococcus_phage	4.6e-15	60.3
WP_000829573.1\|23989_26269_-	AAA family ATPase	Q5YA88	Bacillus_phage	4.6e-277	62.7
WP_001114109.1\|26339_26591_+	hypothetical protein	A0A097BY83	Enterococcus_phage	1.3e-20	52.8
WP_000427885.1\|26583_26781_-	hypothetical protein	NA	NA	NA	NA
WP_032456395.1\|26789_28373_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	1.7e-233	77.8
WP_001870729.1\|28378_28987_-	hypothetical protein	D2XPY9	Bacillus_virus	7.2e-44	45.5
WP_000141563.1\|28986_29592_-	hypothetical protein	A0A097BY29	Enterococcus_phage	2.5e-36	48.2
WP_001167564.1\|29687_30761_-	ATP-binding protein	A0A0K2CZH1	Paenibacillus_phage	9.6e-100	54.2
WP_000156426.1\|30775_32095_-	AAA family ATPase	A0A097BY67	Enterococcus_phage	3.1e-132	57.1
WP_000573547.1\|32078_32309_-	hypothetical protein	NA	NA	NA	NA
WP_000910901.1\|32301_32529_-	hypothetical protein	NA	NA	NA	NA
WP_001123482.1\|32676_32988_-	hypothetical protein	M1Q0Y6	Streptococcus_phage	2.9e-49	87.3
WP_001112862.1\|33067_33259_-	hypothetical protein	A0A141DZR9	Streptococcus_phage	4.7e-18	69.8
WP_000092750.1\|33309_34098_+	hypothetical protein	NA	NA	NA	NA
WP_000739596.1\|34048_34294_-	hypothetical protein	X2L066	Streptococcus_phage	7.4e-08	55.8
WP_000484457.1\|34589_34937_+	helix-turn-helix transcriptional regulator	A0A126GGQ7	Streptococcus_phage	1.3e-42	76.1
WP_000151182.1\|34940_35327_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	2.3e-35	57.6
WP_000353930.1\|35344_35896_+	hypothetical protein	A7J267	Streptococcus_phage	1.7e-60	64.3
WP_000269474.1\|36010_37153_+\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	1.1e-183	82.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_ANEC01000029

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_ANEC01000029_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_ANEC01000029_1

263663-264097

TypeII

II-A

Consensus_repeat	Method
AAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACT	PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	PILER-CR

6 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_ANEC01000029_1

>merge|NZ_ANEC01000029|1|263663-264097|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTGTTATCTGCCATTCAATACTCCTTAAAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATTTTAGAGGTAAAGATACCACAACTAATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAAATCATCTTTATTGACTGTTTTTCCTTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAACAACTTTCTTACAAAAGGTTCTAGTTTTCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACATCACACCAGTCGTTATGATGGATGACTATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGAACATGAAAGATTTTAAAAAAGAACATTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_ANEC01000029|1|1|263663-263831|PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTGT	TATCTGCCATTCAATACTCCTTAAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATT	TTAGAGGTAAAGATACCACAACTAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAAATCATCTTTATTGACTGTTTTTCCTTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAACAACTTTCTTACAAAAGGTTCTAGTTTTCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATCACACCAGTCGTTATGATGGATGACTA
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAACATGAAAGATTTTAAAAAAGAACATT


>NZ_ANEC01000029|1|1|263663-264097|CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTGTTATCTGCCATTCAATACTCCTTAAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATTTTAGAGGTAAAGATACCACAACTAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAAATCATCTTTATTGACTGTTTTTCCTTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AACAACTTTCTTACAAAAGGTTCTAGTTTTCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATCACACCAGTCGTTATGATGGATGACTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAACATGAAAGATTTTAAAAAAGAACATTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_ANEC01000029|1|1|263663-264097|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTGTTATCTGCCATTCAATACTCCTTAAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TATTTTAGAGGTAAAGATACCACAACTAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AAAATCATCTTTATTGACTGTTTTTCCTTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AACAACTTTCTTACAAAAGGTTCTAGTTTTCTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATCACACCAGTCGTTATGATGGATGACTAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAACATGAAAGATTTTAAAAAAGAACATTT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_ANEC01000029|1|2|263929-264097|PILER-CR
	TATCTGCCATTCAATACTCCTTAAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTATT	TTAGAGGTAAAGATACCACAACTAAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAAAATCATCTTTATTGACTGTTTTTCCTTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAACAACTTTCTTACAAAAGGTTCTAGTTTTCTTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	ATCACACCAGTCGTTATGATGGATGACTA
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAACATGAAAGATTTTAAAAAAGAACATT
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_ANEC01000029.1\|WP_000653357.1\|256522_257179_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_ANEC01000029.1\|WP_000929490.1\|261702_262572_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_ANEC01000029.1\|WP_000523795.1\|255024_255762_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_ANEC01000029.1\|WP_000665410.1\|271214_271649_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_ANEC01000029.1\|WP_000065320.1\|274592_275696_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_ANEC01000029.1\|WP_000621139.1\|270750_271215_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_ANEC01000029.1\|WP_001875996.1\|275816_276398_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_ANEC01000029.1\|WP_000159235.1\|253021_253393_+\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_ANEC01000029.1\|WP_000438313.1\|264719_265136_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_ANEC01000029.1\|WP_000122197.1\|262568_262910_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_ANEC01000029.1\|WP_000323544.1\|255762_256533_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_ANEC01000029.1\|WP_000168894.1\|271800_274593_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_ANEC01000029.1\|WP_001019133.1\|265271_267104_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_ANEC01000029.1\|WP_000678287.1\|267349_269983_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|380193
NZ_ANEC01000029.1\|WP_001040077.1\|257567_261701_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_ANEC01000029.1\|WP_000914659.1\|253890_255021_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_ANEC01000029.1\|WP_001241816.1\|253417_253798_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_ANEC01000029.1\|WP_000590706.1\|262896_263562_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_ANEC01000029.1\|WP_000900527.1\|264149_264410_+\|hypothetical-protein	unknown	unknown	unknown
NZ_ANEC01000029.1\|WP_000180008.1\|270082_270742_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336

Protein	Function_ID	Function_description	E-value
NZ_ANEC01000029.1\|WP_000653357.1\|256522_257179_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52
NZ_ANEC01000029.1\|WP_000929490.1\|261702_262572_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	5.3759e-138
NZ_ANEC01000029.1\|WP_000523795.1\|255024_255762_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_ANEC01000029.1\|WP_000665410.1\|271214_271649_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
NZ_ANEC01000029.1\|WP_000065320.1\|274592_275696_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.44123e-105
NZ_ANEC01000029.1\|WP_000621139.1\|270750_271215_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.90455e-18
NZ_ANEC01000029.1\|WP_001875996.1\|275816_276398_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	3.28709e-71
NZ_ANEC01000029.1\|WP_000159235.1\|253021_253393_+\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	7.7979e-28
NZ_ANEC01000029.1\|WP_000438313.1\|264719_265136_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	6.25805e-79
NZ_ANEC01000029.1\|WP_000122197.1\|262568_262910_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.70123e-50
NZ_ANEC01000029.1\|WP_000323544.1\|255762_256533_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_ANEC01000029.1\|WP_000168894.1\|271800_274593_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_ANEC01000029.1\|WP_001019133.1\|265271_267104_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_ANEC01000029.1\|WP_000678287.1\|267349_269983_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	8.24068e-22
NZ_ANEC01000029.1\|WP_001040077.1\|257567_261701_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_ANEC01000029.1\|WP_000914659.1\|253890_255021_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_ANEC01000029.1\|WP_001241816.1\|253417_253798_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_ANEC01000029.1\|WP_000590706.1\|262896_263562_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.61399e-122
NZ_ANEC01000029.1\|WP_000180008.1\|270082_270742_+\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	1.30028e-33

>NZ_ANEC01000029.1|WP_000590706.1|262896_263562_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_ANEC01000029.1|WP_000122197.1|262568_262910_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGSITLLTVTEKQFARMVYLHGEHNMSVANSDSRLVFLGDSYDQD
>NZ_ANEC01000029.1|WP_000929490.1|261702_262572_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLESFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLILSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_ANEC01000029.1|WP_001040077.1|257567_261701_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRFKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATMQEEKYYHEKFPTIYHLRKELADKKEKADLRLVYLALAHIIKFRGHFLIEDDRFDVRNTDIQKQYQAFLEIFDTTFENNHLLSQNVDVEAILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSVAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHHEDLKHLKQFVKASLPENYREVFADSSKDGYAGYIEGKTNQEAFYKYLLKLLTKQEGSEYFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELRAIIRRQSEYYPFLKENQDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRFLAEGFKDFQFLNRKQKETIFNSLFKEKRKVTEKDIISFLNKVDGYEGIAIKGIEKQFNASLSTYHDLKKILGKDFLDNTDNELILEDIVQTLTLFEDREMIKKCLDIYKDFFTESQLKKLYRRHYTGWGRLSAKLINGIRNKENQKTILDYLIDDGSANRNFMQLINDDDLSFKPIIDKARTGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTAKGLSRSRQRLTTLRESLANLKSNILEEKKPKYVKDQVENHHLSDDRLFLYYLQNGRDMYTKKALDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSIEIVKARKMFWKNLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNEVDNGKKICKVKIVTLKSNLVSNFRKEFGFYKIREVNDYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGMYRQKKLSKIVHEDKEEKYSEATRKMFFYSNLMNMFKRVVRLADGSIVVRPVIETGRYMGKTAWDKKKHFATVRKVLSYPQNNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRDDKLMILPKYSLFELENGRRRLLASAGELQKGNELALPTQFMKFLYLASRYNESKGKPEEIEKKQEFVNQHVSYFDDILQLINDFSKRVILADANLEKINKLYQDNKENIPVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>NZ_ANEC01000029.1|WP_000653357.1|256522_257179_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_ANEC01000029.1|WP_000323544.1|255762_256533_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_ANEC01000029.1|WP_000523795.1|255024_255762_+|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_ANEC01000029.1|WP_000914659.1|253890_255021_+|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELIRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWENVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_ANEC01000029.1|WP_001241816.1|253417_253798_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_ANEC01000029.1|WP_000159235.1|253021_253393_+|YbgA-family-protein
MTKEAKLLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE
>NZ_ANEC01000029.1|WP_000900527.1|264149_264410_+|hypothetical-protein
MLGHHCGVLVFCYTEINFQRMWGKAVIRLIQDVIQNLVGQANEITPIYQFDWETYILATKKYERHLEVCLLVENSNCFSDSKRMCR
>NZ_ANEC01000029.1|WP_000438313.1|264719_265136_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>NZ_ANEC01000029.1|WP_001019133.1|265271_267104_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_ANEC01000029.1|WP_000678287.1|267349_269983_+|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKKQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQNNSHYRVNSSKIAGLHHPTSDGFLFNGQGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKVDSKKQSPSSKKPRTENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLASLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_ANEC01000029.1|WP_000180008.1|270082_270742_+|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKG
>NZ_ANEC01000029.1|WP_000621139.1|270750_271215_+|GNAT-family-N-acetyltransferase
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_ANEC01000029.1|WP_000665410.1|271214_271649_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>NZ_ANEC01000029.1|WP_000168894.1|271800_274593_+|cation-transporting-P-type-ATPase
MASTNNVSDTNTCFAKEELEEIFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVEQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDERSTYTVLGDPTEACLNVLLEKSGINRQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDGAKVISGLELSEMTDSQLKKELSGEAVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKTLSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLIGCPFIMIGLDEVRKLFSSRKNKR
>NZ_ANEC01000029.1|WP_000065320.1|274592_275696_+|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEISLEFEKQFAAMVFTIPNINYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGTGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFLGAYHDNSRETK
>NZ_ANEC01000029.1|WP_001875996.1|275816_276398_-|CatB-related-O-acetyltransferase
MRTDMSTGASYPKYRFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448736	Streptococcus phage Javan35, complete genome	6769-6794	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448956	Streptococcus phage Javan48, complete genome	8657-8682	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448781	Streptococcus phage Javan5, complete genome	6769-6794	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448749	Streptococcus phage Javan39, complete genome	8657-8682	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448938	Streptococcus phage Javan44, complete genome	6769-6794	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448911	Streptococcus phage Javan34, complete genome	6769-6794	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	MK448916	Streptococcus phage Javan36, complete genome	6769-6794	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448736	Streptococcus phage Javan35, complete genome	6766-6795	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448956	Streptococcus phage Javan48, complete genome	8654-8683	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448781	Streptococcus phage Javan5, complete genome	6766-6795	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448749	Streptococcus phage Javan39, complete genome	8654-8683	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448938	Streptococcus phage Javan44, complete genome	6766-6795	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448911	Streptococcus phage Javan34, complete genome	6766-6795	0	1.0
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK448916	Streptococcus phage Javan36, complete genome	6766-6795	0	1.0
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	MK448971	Streptococcus phage Javan52, complete genome	19451-19480	0	1.0
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	MK448956	Streptococcus phage Javan48, complete genome	18107-18136	0	1.0
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	MK448851	Streptococcus phage Javan14, complete genome	18773-18802	0	1.0
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448749	Streptococcus phage Javan39, complete genome	20005-20034	0	1.0
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MH853356	Streptococcus phage LF2, partial genome	43016-43045	0	1.0
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448749	Streptococcus phage Javan39, complete genome	20005-20033	0	1.0
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MH853356	Streptococcus phage LF2, partial genome	43017-43045	0	1.0
NZ_ANEC01000029_1	1.1\|263703\|26\|NZ_ANEC01000029\|PILER-CR	263703-263728	26	JX409894	Streptococcus phage LYGO9, complete genome	41612-41637	2	0.923
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	JX409894	Streptococcus phage LYGO9, complete genome	41611-41640	2	0.933
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448859	Streptococcus phage Javan170, complete genome	20220-20248	2	0.931
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448690	Streptococcus phage Javan169, complete genome	20578-20606	2	0.931
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448850	Streptococcus phage Javan132, complete genome	19807-19835	2	0.931
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448676	Streptococcus phage Javan131, complete genome	22730-22758	2	0.931
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448688	Streptococcus phage Javan161, complete genome	20173-20201	2	0.931
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448859	Streptococcus phage Javan170, complete genome	20220-20249	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448690	Streptococcus phage Javan169, complete genome	20578-20607	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448850	Streptococcus phage Javan132, complete genome	19807-19836	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448676	Streptococcus phage Javan131, complete genome	22730-22759	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448688	Streptococcus phage Javan161, complete genome	20173-20202	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448973	Streptococcus phage Javan522, complete genome	19671-19700	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448955	Streptococcus phage Javan478, complete genome	21048-21077	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448778	Streptococcus phage Javan493, complete genome	19213-19242	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448962	Streptococcus phage Javan496, complete genome	9204-9233	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448975	Streptococcus phage Javan526, complete genome	19995-20024	3	0.9
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448782	Streptococcus phage Javan501, complete genome	22353-22382	3	0.9
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448973	Streptococcus phage Javan522, complete genome	19671-19699	3	0.897
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448955	Streptococcus phage Javan478, complete genome	21048-21076	3	0.897
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448778	Streptococcus phage Javan493, complete genome	19213-19241	3	0.897
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448962	Streptococcus phage Javan496, complete genome	9204-9232	3	0.897
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448975	Streptococcus phage Javan526, complete genome	19995-20023	3	0.897
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448782	Streptococcus phage Javan501, complete genome	22353-22381	3	0.897
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	JX409894	Streptococcus phage LYGO9, complete genome	28656-28685	4	0.867
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	MK448675	Streptococcus phage Javan129, complete genome	20470-20499	4	0.867
NZ_ANEC01000029_1	1.7\|263966\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263966-263995	30	JX409895	Streptococcus phage JX01, complete genome	40503-40532	4	0.867
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	KC465899	Pelagibacter phage HTVC008M, complete genome	125202-125231	4	0.867
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	JX409894	Streptococcus phage LYGO9, complete genome	28657-28685	4	0.862
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	MK448675	Streptococcus phage Javan129, complete genome	20470-20498	4	0.862
NZ_ANEC01000029_1	1.9\|263966\|29\|NZ_ANEC01000029\|PILER-CR	263966-263994	29	JX409895	Streptococcus phage JX01, complete genome	40504-40532	4	0.862
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP035396	Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence	5261-5289	5	0.828
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP032856	Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence	45542-45570	5	0.828
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_MG557999	Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence	51741-51769	5	0.828
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_MF497781	Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence	51741-51769	5	0.828
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP035396	Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence	5260-5289	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP032856	Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence	45542-45571	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_MG557999	Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence	51740-51769	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_MF497781	Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence	51740-51769	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MT074138	Bacteroides phage DAC17, complete genome	95749-95778	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MT074136	Bacteroides phage DAC15, complete genome	96339-96368	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP046030	Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence	15565-15594	6	0.8
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	AP014166	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, * SEQUENCING IN PROGRESS *	5438-5467	6	0.8
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_KR091915	Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence	42924-42952	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP025915	Escherichia coli strain 203740 plasmid p203740_35, complete sequence	8594-8622	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_LS999564	Escherichia coli isolate EC-TO143 plasmid 5, complete sequence	682-710	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_LN824136	Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671	16676-16704	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP054370	Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence	19259-19287	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP006640	Escherichia coli PCN061 plasmid PCN061p4, complete sequence	5957-5985	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP029801	Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence	7884-7912	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP015505	Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence	27843-27871	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP026060	Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence	16878-16906	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP024853	Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence	326-354	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_LT985287	Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence	31253-31281	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP028999	Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence	14731-14759	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP027258	Escherichia coli strain EC11 plasmid unnamed3, complete sequence	21719-21747	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP019200	Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence	31777-31805	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP023823	Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence	16676-16704	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP026025	Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence	33043-33071	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP018988	Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence	682-710	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_MK033500	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence	7491-7519	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_MK033501	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence	55790-55818	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_MK033499	Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence	107898-107926	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MT074138	Bacteroides phage DAC17, complete genome	95750-95778	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MT074136	Bacteroides phage DAC15, complete genome	96340-96368	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MN693256	Marine virus AFVG_25M339, complete genome	27548-27576	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MN855807	Siphoviridae sp. isolate 122, partial genome	13518-13546	6	0.793
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	FJ429185	Lactococcus phage P087, complete genome	18714-18742	6	0.793
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MG983840	Escherichia phage myPSH1131, complete genome	41563-41592	7	0.767
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MK373770	Escherichia phage vB_EcoP_WFI101126, complete genome	40651-40680	7	0.767
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MT446410	UNVERIFIED: Escherichia virus TH38, complete genome	54041-54070	7	0.767
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	NC_027395	Phage vB_EcoP_SU10, complete genome	42976-43005	7	0.767
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	MT446386	UNVERIFIED: Escherichia virus TH06, complete genome	5460-5489	7	0.767
NZ_ANEC01000029_1	1.3\|263699\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263699-263728	30	KP308307	Escherichia phage 172-1, complete genome	51406-51435	7	0.767
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NC_017073	Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC3, complete sequence	64611-64640	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_KR091915	Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence	42923-42952	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP025915	Escherichia coli strain 203740 plasmid p203740_35, complete sequence	8594-8623	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_LS999564	Escherichia coli isolate EC-TO143 plasmid 5, complete sequence	682-711	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_LN824136	Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671	16675-16704	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP054370	Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence	19258-19287	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP006640	Escherichia coli PCN061 plasmid PCN061p4, complete sequence	5957-5986	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP029801	Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence	7884-7913	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP015505	Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence	27842-27871	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP026060	Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence	16877-16906	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP024853	Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence	326-355	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_LT985287	Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence	31253-31282	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP028999	Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence	14730-14759	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP027258	Escherichia coli strain EC11 plasmid unnamed3, complete sequence	21718-21747	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP019200	Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence	31777-31806	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP023823	Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence	16675-16704	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP026025	Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence	33042-33071	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP018988	Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence	682-711	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_MK033500	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence	7491-7520	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_MK033501	Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence	55790-55819	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_MK033499	Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence	107898-107927	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MN693256	Marine virus AFVG_25M339, complete genome	27548-27577	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_LR215001	Mycoplasma conjunctivae strain NCTC10147 plasmid 5	7233-7262	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MN855807	Siphoviridae sp. isolate 122, partial genome	13518-13547	7	0.767
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	FJ429185	Lactococcus phage P087, complete genome	18714-18743	7	0.767
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP012103	Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence	20110-20138	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP009352	Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence	2297-2325	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NC_004952	Francisella novicida plasmid pFNL10, complete sequence	111-139	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NC_002109	Francisella tularensis plasmid pOM1, complete sequence	111-139	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	LC494302	Escherichia phage SP27 DNA, complete genome	245480-245508	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	230964-230992	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NC_027364	Escherichia phage PBECO 4, complete genome	39409-39437	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MH383160	Escherichia phage UB, complete genome	99996-100024	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MK327931	Escherichia phage vB_EcoM_G17, complete genome	256258-256286	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MK448636	Streptococcus satellite phage Javan749, complete genome	10387-10415	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	MN693101	Marine virus AFVG_25M559, complete genome	25634-25662	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	KT725776	Bacillus phage vB_BceS-MY192, partial genome	2349-2377	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	187103-187131	7	0.759
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	KM507819	Escherichia phage 121Q, complete genome	246579-246607	7	0.759
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NZ_CP034685	Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence	182880-182909	8	0.733
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NZ_CP043832	Bacillus sp. BS98 plasmid unnamed2	71255-71284	8	0.733
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NZ_CP020434	Bacillus sp. FDAARGOS_235 plasmid 1, complete sequence	216274-216303	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	70939-70968	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP012103	Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence	20110-20139	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_LR214953	Mycoplasma neurolyticum strain NCTC10166 plasmid 3	5510-5539	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP009352	Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence	2297-2326	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NZ_CP051681	Cohnella sp. MFER-1 plasmid unnamed1	74376-74405	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NC_004952	Francisella novicida plasmid pFNL10, complete sequence	110-139	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NC_002109	Francisella tularensis plasmid pOM1, complete sequence	110-139	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	LC494302	Escherichia phage SP27 DNA, complete genome	245480-245509	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	230963-230992	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	NC_027364	Escherichia phage PBECO 4, complete genome	39408-39437	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MH383160	Escherichia phage UB, complete genome	99995-100024	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MK327931	Escherichia phage vB_EcoM_G17, complete genome	256257-256286	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MN871445	UNVERIFIED: Serratia phage KpHz_2, complete genome	75797-75826	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MK448636	Streptococcus satellite phage Javan749, complete genome	10387-10416	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MN871444	UNVERIFIED: Serratia phage KpGz_1, complete genome	13324-13353	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	MN693101	Marine virus AFVG_25M559, complete genome	25633-25662	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	KT725776	Bacillus phage vB_BceS-MY192, partial genome	2349-2378	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	187103-187132	8	0.733
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	KM507819	Escherichia phage 121Q, complete genome	246579-246608	8	0.733
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP046030	Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence	15565-15593	8	0.724
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	NZ_CP051681	Cohnella sp. MFER-1 plasmid unnamed1	74377-74405	8	0.724
NZ_ANEC01000029_1	1.10\|264032\|29\|NZ_ANEC01000029\|PILER-CR	264032-264060	29	HQ683709	Planktothrix phage PaV-LD, complete genome	72162-72190	8	0.724
NZ_ANEC01000029_1	1.8\|264032\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	264032-264061	30	HQ683709	Planktothrix phage PaV-LD, complete genome	72162-72191	9	0.7
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NZ_CP009636	Bacillus cereus 03BB108 plasmid pBFI_2, complete sequence	189787-189816	10	0.667
NZ_ANEC01000029_1	1.5\|263831\|30\|NZ_ANEC01000029\|CRISPRCasFinder,CRT	263831-263860	30	NZ_CP053962	Bacillus cereus strain FDAARGOS_802 plasmid unnamed2, complete sequence	15230-15259	10	0.667

1. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

2. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

3. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

4. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

5. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

6. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

7. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

tgttatctgccattcaatactcctta	CRISPR spacer
tgttatctgccattcaatactcctta	Protospacer
**************************

8. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

9. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

10. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

11. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

12. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

13. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

14. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttgttatctgccattcaatactccttaaaa	Protospacer
******************************

15. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aaaatcatctttattgactgtttttccttc	Protospacer
******************************

16. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aaaatcatctttattgactgtttttccttc	Protospacer
******************************

17. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 0, identity: 1.0

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aaaatcatctttattgactgtttttccttc	Protospacer
******************************

18. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagtcgttatgatggatgactat	Protospacer
******************************

19. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagtcgttatgatggatgactat	Protospacer
******************************

20. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 0, identity: 1.0

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagtcgttatgatggatgacta	Protospacer
*****************************

21. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagtcgttatgatggatgacta	Protospacer
*****************************

22. spacer 1.1|263703|26|NZ_ANEC01000029|PILER-CR matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 2, identity: 0.923

tgttatctgccattcaatactcctta	CRISPR spacer
tattgtctgccattcaatactcctta	Protospacer
*.**.*********************

23. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 2, identity: 0.933

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
ttattgtctgccattcaatactccttaaaa	Protospacer
**.**.************************

24. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 2, identity: 0.931

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgacta	Protospacer
***********..****************

25. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 2, identity: 0.931

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgacta	Protospacer
***********..****************

26. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 2, identity: 0.931

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgacta	Protospacer
***********..****************

27. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 2, identity: 0.931

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgacta	Protospacer
***********..****************

28. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 2, identity: 0.931

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgacta	Protospacer
***********..****************

29. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgactac	Protospacer
***********..****************.

30. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgactac	Protospacer
***********..****************.

31. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgactac	Protospacer
***********..****************.

32. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgactac	Protospacer
***********..****************.

33. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgactac	Protospacer
***********..****************.

34. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

35. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

36. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

37. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

38. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

39. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.9

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttgttatgatggatgatttt	Protospacer
***********.**************.* *

40. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

41. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

42. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

43. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

44. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

45. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 3, identity: 0.897

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttgttatgatggatgattt	Protospacer
***********.**************.*

46. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 4, identity: 0.867

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgatttt	Protospacer
***********..*************.* *

47. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 4, identity: 0.867

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgatttt	Protospacer
***********..*************.* *

48. spacer 1.7|263966|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 4, identity: 0.867

atcacaccagtcgttatgatggatgactat	CRISPR spacer
atcacaccagttattatgatggatgatttt	Protospacer
***********..*************.* *

49. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to KC465899 (Pelagibacter phage HTVC008M, complete genome) position: , mismatch: 4, identity: 0.867

-gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tgaatat-aaagattttaaaaaagtagattt	Protospacer
 ***.** **************** * ****

50. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 4, identity: 0.862

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgattt	Protospacer
***********..*************.*

51. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 4, identity: 0.862

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgattt	Protospacer
***********..*************.*

52. spacer 1.9|263966|29|NZ_ANEC01000029|PILER-CR matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 4, identity: 0.862

atcacaccagtcgttatgatggatgacta	CRISPR spacer
atcacaccagttattatgatggatgattt	Protospacer
***********..*************.*

53. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP035396 (Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.828

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
acacatgaatgattttaaaaaagaacttg	Protospacer
. ******* **************** *

54. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP032856 (Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.828

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
acacatgaatgattttaaaaaagaacttg	Protospacer
. ******* **************** *

55. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_MG557999 (Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence) position: , mismatch: 5, identity: 0.828

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagattttaaaaaagaacctt	Protospacer
*.. .********************* **

56. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_MF497781 (Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence) position: , mismatch: 5, identity: 0.828

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagattttaaaaaagaacctt	Protospacer
*.. .********************* **

57. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP035396 (Bacillus subtilis strain SRCM103697 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
acacatgaatgattttaaaaaagaacttgg	Protospacer
. ******* **************** *

58. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP032856 (Bacillus subtilis subsp. subtilis strain PJ-7 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
acacatgaatgattttaaaaaagaacttgg	Protospacer
. ******* **************** *

59. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_MG557999 (Escherichia coli strain Eco-36682cz plasmid pEco-36682cz, complete sequence) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagattttaaaaaagaaccttc	Protospacer
*.. .********************* **.

60. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_MF497781 (Citrobacter freundii strain Cfr-36049cz plasmid pCrf-36049cz, complete sequence) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagattttaaaaaagaaccttc	Protospacer
*.. .********************* **.

61. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MT074138 (Bacteroides phage DAC17, complete genome) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
aacaatgcaagactttaaaaaagaacatat	Protospacer
.*  *** ****.*************** *

62. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MT074136 (Bacteroides phage DAC15, complete genome) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
aacaatgcaagactttaaaaaagaacatat	Protospacer
.*  *** ****.*************** *

63. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP046030 (Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt---	CRISPR spacer
caccatgaaagattttagaaaag---atttagc	Protospacer
 * **************.*****   ****

64. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to AP014166 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
taaagttaaagattctaaaaaagaagattt	Protospacer
 ** .* *******.********** ****

65. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_KR091915 (Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

66. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP025915 (Escherichia coli strain 203740 plasmid p203740_35, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

67. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_LS999564 (Escherichia coli isolate EC-TO143 plasmid 5, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

68. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_LN824136 (Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

69. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP054370 (Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

70. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP006640 (Escherichia coli PCN061 plasmid PCN061p4, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

71. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP029801 (Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

72. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP015505 (Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

73. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP026060 (Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

74. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP024853 (Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

75. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_LT985287 (Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

76. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP028999 (Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

77. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP027258 (Escherichia coli strain EC11 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

78. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP019200 (Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

79. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP023823 (Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

80. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP026025 (Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

81. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP018988 (Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

82. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_MK033500 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

83. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_MK033501 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

84. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_MK033499 (Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gggggtgaaagatttcaaaaaagaacctt	Protospacer
*.. .**********.********** **

85. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MT074138 (Bacteroides phage DAC17, complete genome) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
aacaatgcaagactttaaaaaagaacata	Protospacer
.*  *** ****.***************

86. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MT074136 (Bacteroides phage DAC15, complete genome) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
aacaatgcaagactttaaaaaagaacata	Protospacer
.*  *** ****.***************

87. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MN693256 (Marine virus AFVG_25M339, complete genome) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
cagcatgaaagatttaaaaaaagaagaag	Protospacer
 *.************ ********* *

88. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MN855807 (Siphoviridae sp. isolate 122, partial genome) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
caccatgaaagatattaaaaaagattact	Protospacer
 * ********** ********** .*.*

89. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to FJ429185 (Lactococcus phage P087, complete genome) position: , mismatch: 6, identity: 0.793

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
caccatgaaagatattaaaaaagattact	Protospacer
 * ********** ********** .*.*

90. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MG983840 (Escherichia phage myPSH1131, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

91. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK373770 (Escherichia phage vB_EcoP_WFI101126, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

92. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MT446410 (UNVERIFIED: Escherichia virus TH38, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

93. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NC_027395 (Phage vB_EcoP_SU10, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

94. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MT446386 (UNVERIFIED: Escherichia virus TH06, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

95. spacer 1.3|263699|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to KP308307 (Escherichia phage 172-1, complete genome) position: , mismatch: 7, identity: 0.767

ttgttatctgccattcaatactccttaaaa	CRISPR spacer
acatgatctgccatttaaaactccttaata	Protospacer
 ..* **********.** ********* *

96. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NC_017073 (Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC3, complete sequence) position: , mismatch: 7, identity: 0.767

aaaatcatctttattgactgtttttccttc	CRISPR spacer
ggcaagatctttattgcctgcttttccttc	Protospacer
.. *  ********** ***.*********

97. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_KR091915 (Klebsiella pneumoniae strain KPC-DK05 plasmid pKPC-DK05, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

98. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP025915 (Escherichia coli strain 203740 plasmid p203740_35, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

99. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_LS999564 (Escherichia coli isolate EC-TO143 plasmid 5, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

100. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_LN824136 (Klebsiella pneumoniae genome assembly MS6671.v1, plasmid : _Plasmid_C_Kpneumoniae_MS6671) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

101. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP054370 (Escherichia coli strain SCU-115 plasmid pSCU-115-2, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

102. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP006640 (Escherichia coli PCN061 plasmid PCN061p4, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

103. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP029801 (Salmonella enterica subsp. enterica serovar Anatum strain R16.0676 plasmid pR16.0676_34k, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

104. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP015505 (Klebsiella pneumoniae strain SKGH01 plasmid unnamed 5, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

105. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP026060 (Proteus mirabilis strain FDAARGOS_80 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

106. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP024853 (Escherichia coli strain AR_0006 plasmid tig00000176, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

107. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_LT985287 (Escherichia coli strain RPC3 plasmid RCS69_pI, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

108. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP028999 (Klebsiella pneumoniae strain AR_0079 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

109. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP027258 (Escherichia coli strain EC11 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

110. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP019200 (Salmonella enterica subsp. enterica serovar Muenster str. 0315 plasmid pCFSAN001297_01, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

111. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP023823 (Escherichia coli strain 7/2 plasmid p7_2.3, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

112. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP026025 (Klebsiella pneumoniae strain 11420 plasmid p11420-KPC, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

113. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP018988 (Escherichia coli strain Ecol_AZ146 plasmid pECAZ146_3, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

114. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_MK033500 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj58k plasmid pConj58k, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

115. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_MK033501 (Salmonella enterica subsp. enterica serovar Anatum strain R13.0957_pConj83k plasmid pConj83k, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

116. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_MK033499 (Escherichia coli strain C600_pConj125k plasmid pConj125k, complete sequence) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gggggtgaaagatttcaaaaaagaaccttc	Protospacer
*.. .**********.********** **.

117. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MN693256 (Marine virus AFVG_25M339, complete genome) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
cagcatgaaagatttaaaaaaagaagaaga	Protospacer
 *.************ ********* *

118. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_LR215001 (Mycoplasma conjunctivae strain NCTC10147 plasmid 5) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
ggaagataaaaattttaaaaaagagcattt	Protospacer
*.* .  ***.*************.*****

119. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MN855807 (Siphoviridae sp. isolate 122, partial genome) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
caccatgaaagatattaaaaaagattacta	Protospacer
 * ********** ********** .*.*

120. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to FJ429185 (Lactococcus phage P087, complete genome) position: , mismatch: 7, identity: 0.767

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
caccatgaaagatattaaaaaagattacta	Protospacer
 * ********** ********** .*.*

121. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP012103 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
aaacatcaaagattttaaaaaatgaggtc	Protospacer
.***** *************** .* .*.

122. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP009352 (Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaata	Protospacer
  .****** **************. **

123. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NC_004952 (Francisella novicida plasmid pFNL10, complete sequence) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaata	Protospacer
  .****** **************. **

124. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NC_002109 (Francisella tularensis plasmid pOM1, complete sequence) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaata	Protospacer
  .****** **************. **

125. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

126. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

127. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

128. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

129. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

130. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MK448636 (Streptococcus satellite phage Javan749, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gtttataaaagattttaaaaaagaaatct	Protospacer
*  .**.******************  .*

131. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to MN693101 (Marine virus AFVG_25M559, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
aagagtagaagaatttaaaaaagaacatt	Protospacer
.*. .*..**** ****************

132. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to KT725776 (Bacillus phage vB_BceS-MY192, partial genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
gtggatgattgattttaaaaaagaacaag	Protospacer
* . ****  *****************

133. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

134. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 7, identity: 0.759

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacaga	Protospacer
  *.******* *** ***********

135. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP034685 (Bacillus sp. BD59S plasmid pBTBD59S2, complete sequence) position: , mismatch: 8, identity: 0.733

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aggtagatctatattgactgttgttccttt	Protospacer
*..   **** *********** ******.

136. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP043832 (Bacillus sp. BS98 plasmid unnamed2) position: , mismatch: 8, identity: 0.733

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aggtagatctatattgactgttgttccttt	Protospacer
*..   **** *********** ******.

137. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP020434 (Bacillus sp. FDAARGOS_235 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaatcatctttattgactgtttttccttc	CRISPR spacer
aggtagatctatattgactgttgttccttt	Protospacer
*..   **** *********** ******.

138. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tatactagtagaatttaaaaaagaacattt	Protospacer
 *   *.. *** *****************

139. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP012103 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-4, complete sequence) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
aaacatcaaagattttaaaaaatgaggtcg	Protospacer
.***** *************** .* .*.

140. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_LR214953 (Mycoplasma neurolyticum strain NCTC10166 plasmid 3) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
aattgataaaaattttaaaaaacaacattt	Protospacer
.* ..  ***.*********** *******

141. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP009352 (Francisella tularensis subsp. novicida F6168 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaatag	Protospacer
  .****** **************. **

142. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP051681 (Cohnella sp. MFER-1 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcacatgaacgattttgaaaaagaaacggt	Protospacer
  ******* ******.********    *

143. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NC_004952 (Francisella novicida plasmid pFNL10, complete sequence) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaatag	Protospacer
  .****** **************. **

144. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NC_002109 (Francisella tularensis plasmid pOM1, complete sequence) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
ttgcatgaacgattttaaaaaagagaatag	Protospacer
  .****** **************. **

145. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

146. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

147. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

148. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

149. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

150. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MN871445 (UNVERIFIED: Serratia phage KpHz_2, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
attcctcttagatttaaaaaaagaacattt	Protospacer
.  * *   ****** **************

151. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MK448636 (Streptococcus satellite phage Javan749, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gtttataaaagattttaaaaaagaaatcta	Protospacer
*  .**.******************  .*

152. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MN871444 (UNVERIFIED: Serratia phage KpGz_1, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
attcctcttagatttaaaaaaagaacattt	Protospacer
.  * *   ****** **************

153. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to MN693101 (Marine virus AFVG_25M559, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
aagagtagaagaatttaaaaaagaacattg	Protospacer
.*. .*..**** ****************

154. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to KT725776 (Bacillus phage vB_BceS-MY192, partial genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
gtggatgattgattttaaaaaagaacaagg	Protospacer
* . ****  *****************

155. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

156. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 8, identity: 0.733

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
tcatatgaaagctttgaaaaaagaacagaa	Protospacer
  *.******* *** ***********

157. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP046030 (Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
caccatgaaagattttagaaaagatttag	Protospacer
 * **************.****** .

158. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to NZ_CP051681 (Cohnella sp. MFER-1 plasmid unnamed1) position: , mismatch: 8, identity: 0.724

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
tcacatgaacgattttgaaaaagaaacgg	Protospacer
  ******* ******.********

159. spacer 1.10|264032|29|NZ_ANEC01000029|PILER-CR matches to HQ683709 (Planktothrix phage PaV-LD, complete genome) position: , mismatch: 8, identity: 0.724

gaacatgaaagattttaaaaaagaacatt	CRISPR spacer
ccacatgacagattttaacaaagaattgg	Protospacer
  ****** ********* ******.

160. spacer 1.8|264032|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to HQ683709 (Planktothrix phage PaV-LD, complete genome) position: , mismatch: 9, identity: 0.7

gaacatgaaagattttaaaaaagaacattt	CRISPR spacer
ccacatgacagattttaacaaagaattggc	Protospacer
  ****** ********* ******.   .

161. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP009636 (Bacillus cereus 03BB108 plasmid pBFI_2, complete sequence) position: , mismatch: 10, identity: 0.667

aaaatcatctttattgactgtttttccttc	CRISPR spacer
ttaatcatctttattaactgtttaagaaat	Protospacer
  *************.*******      .

162. spacer 1.5|263831|30|NZ_ANEC01000029|CRISPRCasFinder,CRT matches to NZ_CP053962 (Bacillus cereus strain FDAARGOS_802 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.667

aaaatcatctttattgactgtttttccttc	CRISPR spacer
ttaatcatctttattaactgtttaagaaat	Protospacer
  *************.*******      .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

347238 : 356622

uncultured_Caudovirales_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000120355.1\|347238_347940_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.2e-35	39.9
WP_000246600.1\|348076_350197_-	type I DNA topoisomerase	E3T4K4	Cafeteria_roenbergensis_virus	1.4e-102	37.7
WP_001015250.1\|350291_351134_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	8.5e-27	35.8
WP_000162771.1\|351271_352300_-	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000614751.1\|352361_353123_-	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.7e-18	28.6
WP_000588576.1\|353119_354094_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	3.6e-05	21.2
WP_000735588.1\|354090_355053_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	3.3e-83	50.3
WP_000136509.1\|355291_355840_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_000201088.1\|355860_356622_-	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	1.5e-25	40.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_ANEC01000015

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NZ_ANEC01000015.1|WP_000384271.1|64583_64910_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_ANEC01000015.1|WP_000384271.1|64583_64910_+|hypothetical-protein

64583_64910_+

108 aa aa

AcrIIA21

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3639\|WP_000384271.1\|AcrIIA21\|II-A\|Verified\|Streptococcus	1.0	1	1.0

8. NZ_ANEC01000020

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

113 : 37534

Streptococcus_phage(79.59%)

tail,terminase,portal,holin,integrase,capsid

attL 48:59|attR 5237:5248

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
48:59	attL	NA	NA	NA	NA
WP_017646862.1\|113_1256_-\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	1.3e-182	82.4
WP_000442169.1\|1383_1593_-	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	3.5e-06	47.7
WP_000700104.1\|1644_2025_-	ImmA/IrrE family metallo-endopeptidase	J7KBR5	Streptococcus_phage	8.2e-70	100.0
WP_000555955.1\|2011_2371_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.7e-45	80.7
WP_000257547.1\|2562_2781_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	9.5e-31	90.1
WP_000158652.1\|2878_3211_+	hypothetical protein	J7KBZ0	Streptococcus_phage	8.4e-55	100.0
WP_001247542.1\|3224_3368_+	hypothetical protein	J7KIV4	Streptococcus_phage	1.6e-18	97.9
WP_000360288.1\|3315_3651_-	hypothetical protein	J7KDN7	Streptococcus_phage	7.8e-16	69.1
WP_000263692.1\|3796_3982_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	4.1e-27	100.0
WP_001123481.1\|4060_4372_+	hypothetical protein	M1Q0Y6	Streptococcus_phage	3.4e-50	88.2
WP_001058282.1\|4601_4802_+	hypothetical protein	J7KK69	Streptococcus_phage	9.3e-33	100.0
WP_000650504.1\|4798_5089_+	hypothetical protein	J7KDN2	Streptococcus_phage	8.2e-38	100.0
WP_000704951.1\|5075_5759_+	AAA family ATPase	J7KC09	Streptococcus_phage	4.6e-124	98.2
5237:5248	attR	NA	NA	NA	NA
WP_047198501.1\|5794_7198_+	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	7.9e-195	72.5
WP_000896928.1\|7202_7685_+	DUF669 domain-containing protein	A0A1P8BMD4	Lactococcus_phage	1.1e-60	71.3
WP_000203210.1\|7702_9256_+	hypothetical protein	A0A1P8BM51	Lactococcus_phage	5.7e-210	70.2
WP_000274892.1\|9524_10394_+	hypothetical protein	A0A1P8BME8	Lactococcus_phage	3.4e-103	65.6
WP_001076208.1\|10347_10695_+	VRR-NUC domain-containing protein	J7KC03	Streptococcus_phage	4.9e-45	87.4
WP_000763908.1\|10773_11070_+	DUF1599 domain-containing protein	J7KBY0	Streptococcus_phage	1.2e-41	87.8
WP_000150115.1\|11053_11293_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	7.5e-05	55.6
WP_000159368.1\|11323_11488_+	hypothetical protein	NA	NA	NA	NA
WP_000139628.1\|11484_11754_+	hypothetical protein	A7J287	Streptococcus_phage	1.8e-23	69.7
WP_017646863.1\|11897_12422_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	7.1e-24	43.4
WP_025195441.1\|12441_12741_+	hypothetical protein	M1PFH6	Streptococcus_phage	6.3e-17	44.8
WP_000221696.1\|12928_13123_+	hypothetical protein	NA	NA	NA	NA
WP_000660741.1\|13119_13386_+	hypothetical protein	NA	NA	NA	NA
WP_011324937.1\|13773_14202_+	DUF1492 domain-containing protein	A0A0B5A564	Streptococcus_phage	1.1e-30	48.6
WP_017646473.1\|14770_15148_+	HNH endonuclease	Q7Y4J1	Streptococcus_phage	2.1e-41	71.3
WP_000725958.1\|15298_15655_+	hypothetical protein	A0A0B5A7G9	Streptococcus_phage	1.3e-24	60.0
WP_001108673.1\|15651_16920_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	8.2e-191	76.8
WP_000227335.1\|16912_18133_+	hypothetical protein	Q7Y4I9	Streptococcus_phage	7.8e-114	66.7
WP_000421991.1\|18132_18321_+	hypothetical protein	NA	NA	NA	NA
WP_000256854.1\|18428_19844_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	1.4e-215	74.8
WP_001288696.1\|19924_20389_+	DUF4355 domain-containing protein	A0A0B5A7G6	Streptococcus_phage	9.7e-41	51.9
WP_000841024.1\|20391_21294_+\|capsid	phage major capsid protein	A0A0B5A5W3	Streptococcus_phage	1.3e-145	85.7
WP_000640308.1\|21290_21506_+	hypothetical protein	M1PRX2	Streptococcus_phage	3.2e-07	49.3
WP_000180799.1\|21519_21951_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	1.1e-46	69.3
WP_001096306.1\|21901_22240_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	4.6e-40	66.1
WP_000032787.1\|22232_22469_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_000573598.1\|22469_22805_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_000226353.1\|22814_23372_+\|tail	tail protein	M1PKG8	Streptococcus_phage	3.4e-64	65.8
WP_000858406.1\|23371_23617_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	9.7e-16	55.3
WP_000916438.1\|23631_24003_+	DUF5361 domain-containing protein	A0A1P8BMT6	Lactococcus_phage	7.3e-31	54.0
WP_017646865.1\|24002_26015_+	hypothetical protein	Q9F4J3	Streptococcus_phage	9.8e-13	58.9
WP_000228809.1\|26008_27541_+	hypothetical protein	J7KH53	Streptococcus_phage	4.7e-201	73.6
WP_000955545.1\|27541_31663_+	CHAP domain-containing protein	J7KBT9	Streptococcus_phage	0.0e+00	79.0
WP_000206874.1\|31663_33667_+	hypothetical protein	J7KC14	Streptococcus_phage	1.1e-295	77.1
WP_000889198.1\|33678_34071_+	DUF1366 domain-containing protein	J7KKA3	Streptococcus_phage	2.3e-11	38.7
WP_001017826.1\|34230_34533_+	hypothetical protein	J7KH30	Streptococcus_phage	5.2e-27	63.4
WP_000609111.1\|34525_34753_+\|holin	phage holin	A7J2B3	Streptococcus_phage	1.7e-30	97.3
WP_017646866.1\|34878_36210_+	lysin	J7KIY0	Streptococcus_phage	1.3e-263	99.3
WP_001061853.1\|36344_37241_+	sensor histidine kinase	J7KDG8	Streptococcus_phage	1.8e-168	100.0
WP_000258211.1\|37234_37534_+	STAS-like domain-containing protein	J7KJ12	Streptococcus_phage	3.8e-46	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_ANEC01000028

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

61887 : 87539

Streptococcus_phage(40.0%)

protease,integrase,transposase

attL 73171:73186|attR 89875:89890

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017646908.1\|61887_63720_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	6.0e-94	36.5
WP_017646909.1\|63810_64158_+	conjugal transfer protein TrbC	NA	NA	NA	NA
WP_017646910.1\|64168_65242_+	hypothetical protein	NA	NA	NA	NA
WP_017646911.1\|65259_66003_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_017646912.1\|66072_68670_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_017646913.1\|68689_69169_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_025195446.1\|69495_69753_+	hypothetical protein	NA	NA	NA	NA
WP_017646915.1\|69745_72895_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_017646916.1\|72995_73475_+	hypothetical protein	NA	NA	NA	NA
73171:73186	attL	NA	NA	NA	NA
WP_025194622.1\|73592_75671_+	hypothetical protein	NA	NA	NA	NA
WP_000883908.1\|75676_75961_+	hypothetical protein	NA	NA	NA	NA
WP_000343796.1\|76103_76409_+	hypothetical protein	NA	NA	NA	NA
WP_000985696.1\|76408_77053_+	hypothetical protein	NA	NA	NA	NA
WP_017646917.1\|77062_79012_+	virulence factor	NA	NA	NA	NA
WP_017646918.1\|79025_79286_+	hypothetical protein	NA	NA	NA	NA
WP_017646919.1\|79299_80628_+	CHAP domain-containing protein	NA	NA	NA	NA
WP_025195447.1\|80645_81233_+	hypothetical protein	NA	NA	NA	NA
WP_017646921.1\|82199_82478_+	hypothetical protein	NA	NA	NA	NA
WP_017646922.1\|82512_82848_+	hypothetical protein	NA	NA	NA	NA
WP_017646923.1\|82985_84320_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_001068667.1\|84780_85128_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_071659971.1\|85272_85887_-\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001872365.1\|85889_86156_-	hypothetical protein	Q77YW7	Streptococcus_phage	9.2e-20	65.2
WP_000640620.1\|86155_86560_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	1.3e-20	43.6
WP_001122304.1\|86721_86922_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_001865698.1\|86943_87204_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001867107.1\|87329_87539_+\|transposase	transposase	NA	NA	NA	NA
89875:89890	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage