CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number	Anti-CRISPR protein number
NZ_JHUU01000018	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00008.8_C, whole genome shotgun sequence	0 crisprs	csa3	1	0
NZ_JHUU01000006	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00001.1_C, whole genome shotgun sequence	2 crisprs	WYL,casR,RT	2	0
NZ_JHUU01000019	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00009.9_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_JHUU01000005	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00014.14_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_JHUU01000002	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00011.11_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_KK211034	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00006.6, whole genome shotgun sequence	0 crisprs	cas3,DinG,csa3	1	0
NZ_JHUU01000011	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00004.4_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_JHUU01000004	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00013.13_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_JHUU01000001	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00010.10_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_JHUU01000017	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00007.7_C, whole genome shotgun sequence	0 crisprs	NA	1	0
NZ_JHUU01000003	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00012.12_C, whole genome shotgun sequence	0 crisprs	NA	0	0
NZ_KK211032	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00002.2, whole genome shotgun sequence	1 crisprs	DinG	1	1
NZ_JHUU01000010	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00003.3_C, whole genome shotgun sequence	0 crisprs	cas3,DEDDh	1	0
NZ_KK211033	Listeria monocytogenes Lm19860 P891DRAFT_scaffold00005.5, whole genome shotgun sequence	0 crisprs	csa3,WYL	1	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

69842 : 76672

Streptococcus_phage(50.0%)

transposase,integrase

attL 70577:70595|attR 77095:77113

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726384.1\|69842_70523_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.2e-92	69.0
70577:70595	attL	NA	NA	NA	NA
WP_023558764.1\|70582_71086_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	6.6e-19	35.9
WP_003726382.1\|71117_71498_+	hypothetical protein	NA	NA	NA	NA
WP_003726381.1\|71730_73848_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.3e-235	62.6
WP_003726380.1\|73844_74204_-	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	5.4e-23	48.2
WP_003725299.1\|74477_75077_-	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	1.8e-15	31.8
WP_003725298.1\|75235_76672_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2H4JGQ6	uncultured_Caudovirales_phage	9.4e-18	24.8
77095:77113	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_JHUU01000006

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CRISPR-Cas detection and classification

Crispr_ID: NZ_JHUU01000006_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JHUU01000006_1

264579-265163

Orphan

Consensus_repeat	Method
GATGTAAGTAATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of NZ_JHUU01000006_1

>merge|NZ_JHUU01000006|1|264579-265163|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTGGATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>NZ_JHUU01000006|1|1|264579-265163|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTG
GATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JHUU01000006.1\|WP_003728092.1\|257718_259269_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_JHUU01000006.1\|WP_003721271.1\|275075_275441_+\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NZ_JHUU01000006.1\|WP_003727318.1\|268964_269270_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_JHUU01000006.1\|WP_003725209.1\|274438_274918_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_JHUU01000006.1\|WP_009929138.1\|251355_252504_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_JHUU01000006.1\|WP_003721253.1\|268451_268937_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_003728986.1\|271394_273095_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_JHUU01000006.1\|WP_026747117.1\|267949_268432_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_026747116.1\|266126_267884_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_JHUU01000006.1\|WP_003725199.1\|269345_269612_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_003740428.1\|253611_255207_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_JHUU01000006.1\|WP_023550313.1\|261704_263786_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_JHUU01000006.1\|WP_003725189.1\|255341_256625_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_JHUU01000006.1\|WP_003728093.1\|256625_257726_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_JHUU01000006.1\|WP_003725208.1\|273245_274349_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_JHUU01000006.1\|WP_003733207.1\|270724_271285_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_JHUU01000006.1\|WP_003725186.1\|249199_251359_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_JHUU01000006.1\|WP_003721242.1\|252508_253456_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_JHUU01000006.1\|WP_003734632.1\|248327_249083_-\|DUF4866-family-protein	unknown	unknown	gnl\|CDD\|379782
NZ_JHUU01000006.1\|WP_023550311.1\|259902_261441_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260

Protein	Function_ID	Function_description	E-value
NZ_JHUU01000006.1\|WP_003728092.1\|257718_259269_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_JHUU01000006.1\|WP_003721271.1\|275075_275441_+\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NZ_JHUU01000006.1\|WP_003728986.1\|271394_273095_+\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_JHUU01000006.1\|WP_003725209.1\|274438_274918_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_JHUU01000006.1\|WP_009929138.1\|251355_252504_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52
NZ_JHUU01000006.1\|WP_003727318.1\|268964_269270_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.34504e-05
NZ_JHUU01000006.1\|WP_026747116.1\|266126_267884_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.49851e-29
NZ_JHUU01000006.1\|WP_003740428.1\|253611_255207_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_JHUU01000006.1\|WP_023550313.1\|261704_263786_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.76219e-29
NZ_JHUU01000006.1\|WP_003725189.1\|255341_256625_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_JHUU01000006.1\|WP_003728093.1\|256625_257726_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_JHUU01000006.1\|WP_003725208.1\|273245_274349_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_JHUU01000006.1\|WP_003733207.1\|270724_271285_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_JHUU01000006.1\|WP_003725186.1\|249199_251359_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_JHUU01000006.1\|WP_003721242.1\|252508_253456_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_JHUU01000006.1\|WP_003734632.1\|248327_249083_-\|DUF4866-family-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_JHUU01000006.1\|WP_023550311.1\|259902_261441_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19

>NZ_JHUU01000006.1|WP_023550313.1|261704_263786_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLIAEEVAQEKPAEVENLEEIPTTDELMQNPEVREQPVADSDDPDLTAVSSGDYWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDFSSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_JHUU01000006.1|WP_023550311.1|259902_261441_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_JHUU01000006.1|WP_003728092.1|257718_259269_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_JHUU01000006.1|WP_003728093.1|256625_257726_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_JHUU01000006.1|WP_003725189.1|255341_256625_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_JHUU01000006.1|WP_003740428.1|253611_255207_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_JHUU01000006.1|WP_003721242.1|252508_253456_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_JHUU01000006.1|WP_009929138.1|251355_252504_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_JHUU01000006.1|WP_003725186.1|249199_251359_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_JHUU01000006.1|WP_003734632.1|248327_249083_-|DUF4866-family-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_JHUU01000006.1|WP_026747116.1|266126_267884_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGSANVSTAQERDTTNKLPEVELGSLDTSNIIAEEVAQEKPAEVEQLEEIPTTDELMQNPDVLEQPVADSDDTDLTVVSSGDFWTIYRNTVNNEYSLCMFGNVPSSRPTAWNTYLNRIKHIEIEEATLTGSFASYFSGDYFTVLESVKIEQCNLSGVTSFEKAFYNSGIEKVIIRDNDYPTAPSLLTTQYMFQLCRKLSELDLSGLDTSAITNIYGMFQFCSGLEELDLSHFDTSSVTNMYSMFSGCGSLEILDVSNWDTSSVTNMNRMFQNCTSLEELDLSTFDTSSMTDMGMMFNGCTALKSLYLDNFTDAAIMTDMFTGTTSLTYLFVSHNLSTFNNLENTSWYDEKNWVQFSNLSQLQTYHRNQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYGETTISENNKLTLSNTADATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYE
>NZ_JHUU01000006.1|WP_026747117.1|267949_268432_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKDDESTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_JHUU01000006.1|WP_003721253.1|268451_268937_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_JHUU01000006.1|WP_003727318.1|268964_269270_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFFLSPDRVQASQTVVEVLISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_JHUU01000006.1|WP_003725199.1|269345_269612_+|hypothetical-protein
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_JHUU01000006.1|WP_003733207.1|270724_271285_+|TetR/AcrR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_JHUU01000006.1|WP_003728986.1|271394_273095_+|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_JHUU01000006.1|WP_003725208.1|273245_274349_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_JHUU01000006.1|WP_003725209.1|274438_274918_+|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_JHUU01000006.1|WP_003721271.1|275075_275441_+|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK

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Crispr_ID: NZ_JHUU01000006_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JHUU01000006_2

266799-267056

Orphan

Consensus_repeat	Method
GATACCAGTTCCGTTACTAATATG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_JHUU01000006_2

>merge|NZ_JHUU01000006|2|266799-267056|CRISPRCasFinder
GATACGAGTGCTATAACTAATATATATGGCATGTTTCAATTTTGCTCTGGTCTTGAAGAGTTAGATTTAAGTCATTTTGATACCAGTTCCGTTACTAATATGTATTCCATGTTTTCGGGTTGTGGATCACTGGAGATTTTGGATGTAAGCAATTGGGATACGAGTTCCGTTACTAATATGAATAGAATGTTTCAAAATTGTACTAGTCTTGAAGAGCTAGATTTAAGTACCTTTGATACCAGTTCAATGACTGACATG

>NZ_JHUU01000006|2|1|266799-267056|CRISPRCasFinder
GATACGAGTGCTATAACTAATATA	TATGGCATGTTTCAATTTTGCTCTGGTCTTGAAGAGTTAGATTTAAGTCATTTT
GATACCAGTTCCGTTACTAATATG	TATTCCATGTTTTCGGGTTGTGGATCACTGGAGATTTTGGATGTAAGCAATTGG
GATACGAGTTCCGTTACTAATATG	AATAGAATGTTTCAAAATTGTACTAGTCTTGAAGAGCTAGATTTAAGTACCTTT
GATACCAGTTCAATGACTGACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JHUU01000006.1\|WP_003728092.1\|257718_259269_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_JHUU01000006.1\|WP_003721271.1\|275075_275441_+\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NZ_JHUU01000006.1\|WP_003727318.1\|268964_269270_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_JHUU01000006.1\|WP_003725208.1\|273245_274349_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_JHUU01000006.1\|WP_003725209.1\|274438_274918_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_JHUU01000006.1\|WP_009929138.1\|251355_252504_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_JHUU01000006.1\|WP_026747115.1\|263921_265991_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_JHUU01000006.1\|WP_003728986.1\|271394_273095_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_JHUU01000006.1\|WP_026747117.1\|267949_268432_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_003725189.1\|255341_256625_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_JHUU01000006.1\|WP_003721253.1\|268451_268937_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_003740428.1\|253611_255207_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_JHUU01000006.1\|WP_023550313.1\|261704_263786_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_JHUU01000006.1\|WP_003728093.1\|256625_257726_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_JHUU01000006.1\|WP_023550311.1\|259902_261441_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_JHUU01000006.1\|WP_003733207.1\|270724_271285_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_JHUU01000006.1\|WP_003725199.1\|269345_269612_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JHUU01000006.1\|WP_003725186.1\|249199_251359_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_JHUU01000006.1\|WP_003731249.1\|275714_277478_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238824
NZ_JHUU01000006.1\|WP_003721242.1\|252508_253456_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786

Protein	Function_ID	Function_description	E-value
NZ_JHUU01000006.1\|WP_003728092.1\|257718_259269_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_JHUU01000006.1\|WP_003721271.1\|275075_275441_+\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NZ_JHUU01000006.1\|WP_026747115.1\|263921_265991_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	8.72154e-31
NZ_JHUU01000006.1\|WP_003725209.1\|274438_274918_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_JHUU01000006.1\|WP_009929138.1\|251355_252504_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52
NZ_JHUU01000006.1\|WP_003727318.1\|268964_269270_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.34504e-05
NZ_JHUU01000006.1\|WP_003728986.1\|271394_273095_+\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_JHUU01000006.1\|WP_003725189.1\|255341_256625_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_JHUU01000006.1\|WP_003731249.1\|275714_277478_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|238824	cd01646, RT_Bac_retron_I, RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	1.43128e-28
NZ_JHUU01000006.1\|WP_003740428.1\|253611_255207_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_JHUU01000006.1\|WP_023550313.1\|261704_263786_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.76219e-29
NZ_JHUU01000006.1\|WP_003728093.1\|256625_257726_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_JHUU01000006.1\|WP_023550311.1\|259902_261441_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19
NZ_JHUU01000006.1\|WP_003725208.1\|273245_274349_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_JHUU01000006.1\|WP_003733207.1\|270724_271285_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_JHUU01000006.1\|WP_003725186.1\|249199_251359_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_JHUU01000006.1\|WP_003721242.1\|252508_253456_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102

>NZ_JHUU01000006.1|WP_026747115.1|263921_265991_+|BspA-family-leucine-rich-repeat-surface-protein
MKKLSIRVILIVTIIFIACGSANVSIAQERDIINKLPEVELGSLYTSNLITEEVAQDKPAEVENLEQAPTTDDLVQNPDVLEQPIADSDDSDLTVVNSGDFWTIYRNTVNGEYSLHMFGNVPSSKPTAWNSYLNRIKHIEIEEATLTGNFSSYFRNNVFTVLESVRIERSNLSRVTSFALAFYGSGIEKVIIRDNNYPTAPSLLTTEGMFKNCSNLMEVDLSGLDTSAVTTMWDMFNSCRALEELDVSNFDTSSVTNMSYMFYDNRNLEVLDVSNLDTGSVTNMYAMFEDCTSLEELDVSNFDTSSVTDMYRVFNGCEKLKKLDVSNFDTSSATAMVQMFRNCSALEKLDVSNFNTSLVTDMRAMFAGCTSLEALDVSNFDTSSVTNMAAMFSDNEKLEKLDLSTFDTSSVTNMGTMFKNCTALKSLFLDNFTHAASSTDMFTGTTSLSYLFVSHNVSNFNGLENTNWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGEFLSLTMDAMGGQFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYEETTISESNKLTLSNTADTTVQCLAPLSWDGSETNPKNAILTLAPGSEITEGDAVMEIESPENIQAGTYTGNLVFSINYE
>NZ_JHUU01000006.1|WP_023550313.1|261704_263786_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLIAEEVAQEKPAEVENLEEIPTTDELMQNPEVREQPVADSDDPDLTAVSSGDYWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDFSSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_JHUU01000006.1|WP_023550311.1|259902_261441_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_JHUU01000006.1|WP_003728092.1|257718_259269_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_JHUU01000006.1|WP_003728093.1|256625_257726_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_JHUU01000006.1|WP_003725189.1|255341_256625_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_JHUU01000006.1|WP_003740428.1|253611_255207_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_JHUU01000006.1|WP_003721242.1|252508_253456_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_JHUU01000006.1|WP_009929138.1|251355_252504_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_JHUU01000006.1|WP_003725186.1|249199_251359_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_JHUU01000006.1|WP_026747117.1|267949_268432_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKDDESTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_JHUU01000006.1|WP_003721253.1|268451_268937_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_JHUU01000006.1|WP_003727318.1|268964_269270_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFFLSPDRVQASQTVVEVLISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_JHUU01000006.1|WP_003725199.1|269345_269612_+|hypothetical-protein
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_JHUU01000006.1|WP_003733207.1|270724_271285_+|TetR/AcrR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_JHUU01000006.1|WP_003728986.1|271394_273095_+|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_JHUU01000006.1|WP_003725208.1|273245_274349_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_JHUU01000006.1|WP_003725209.1|274438_274918_+|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_JHUU01000006.1|WP_003721271.1|275075_275441_+|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
>NZ_JHUU01000006.1|WP_003731249.1|275714_277478_+|RNA-directed-DNA-polymerase
MRKKVDVLSMDNEKAREFFMKPSSYFSQNLPKYFNLGYLLESAESKLGKKQLKKEMYFENKVYSNFPNVNFLIQTNKTISTYRPITLLHPYIYVDYVNFLTEIKIWEELKERFQNLQEEVKEKIICSSLPFDIETSKEDDSKKEMALNFWKSIEQETIKYSLGYNYLLKLDISNFYGSIYTHTLCWAFHGENYSKEAKNSKNLQNLTGDKCDRKFQWMNYGETVGIPQGNVISDLMSELLLAYIDSELVKKIDDEIDYKIIRYRDDYRIFTKRLEDSTLVKRELVVLLQRFKLNLGESKTSQTTDIISGSLKEDKMYWIEHDPVTKLTSDKFYRSPKILMKKSLEEHKNKKYKTRVFNEFFKKHFHNRTYQATLQKHLLIIKVFSDLYPNSGQLIAALHEFEGRLLDLNYKDFRNIGTEVEVLIAILVDIIKKNPKITEIGVKLLSTLLKKINFEEFEMKYLESNNSNEVQSDFEVKLAYINSVNHKLSNSNYNDYLEIWMQRLVVKNLKESTTLSDLYIEQSKNELVKFCNSIIRGKEMIQIFNEDWLKDEHKIELSKFINLNEIDKLTDIISDDEIYLAEYNQMT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

881572 : 888995

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003730941.1\|881572_881956_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003727002.1\|881977_882961_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	2.0e-11	33.8
WP_026747136.1\|882975_883989_+	glycosyltransferase	A0A1V0SAH6	Catovirus	1.8e-10	31.2
WP_003721509.1\|884197_885688_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_023550416.1\|885699_886524_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.3e-67	52.2
WP_009929872.1\|886536_886845_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_009929871.1\|886905_887310_+	PTS lactose transporter subunit IIBC	NA	NA	NA	NA
WP_023550418.1\|887438_888995_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.0e-18	29.2

DBSCAN-SWA_2

985867 : 1053719

Listeria_phage(84.75%)

portal,terminase,tail,capsid,protease,integrase,holin,tRNA

attL 1010488:1010504|attR 1054019:1054035

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009927922.1\|985867_988276_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003721621.1\|988436_989138_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-33	35.8
WP_023550449.1\|989151_992562_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_003724750.1\|992659_993112_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003724751.1\|993127_996328_+	MMPL family transporter	NA	NA	NA	NA
WP_003724752.1\|996431_997106_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	3.4e-50	47.7
WP_012681263.1\|997143_998070_-	ribonuclease HIII	NA	NA	NA	NA
WP_003740576.1\|998223_998487_+	cell division protein ZapA	NA	NA	NA	NA
WP_003726937.1\|998486_999029_+	CvpA family protein	NA	NA	NA	NA
WP_003726936.1\|999120_1000833_+	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	1.9e-17	24.5
WP_003734676.1\|1000855_1003213_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.0e-21	50.4
WP_003723853.1\|1003293_1003605_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	5.4e-19	39.6
WP_003726544.1\|1003680_1005492_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_003726934.1\|1005672_1006887_+	aspartate kinase	NA	NA	NA	NA
WP_012681265.1\|1006942_1007437_-	YslB family protein	NA	NA	NA	NA
WP_003723856.1\|1007584_1008385_+	glutamate racemase	NA	NA	NA	NA
WP_003730987.1\|1008397_1009144_+	ribonuclease PH	NA	NA	NA	NA
WP_009928777.1\|1009146_1009758_+	XTP/dITP diphosphatase	Q66YC8	Euphorbia_ringspot_virus	8.7e-05	28.0
WP_003726034.1\|1009794_1010319_+	metallophosphoesterase	NA	NA	NA	NA
1010488:1010504	attL	NA	NA	NA	NA
WP_026747144.1\|1010604_1011759_-\|integrase	site-specific integrase	A8ATC7	Listeria_phage	1.8e-205	93.2
WP_014930257.1\|1011887_1012751_-	hypothetical protein	NA	NA	NA	NA
WP_026747145.1\|1012802_1013255_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	9.1e-76	87.3
WP_012951519.1\|1013271_1013595_-	helix-turn-helix transcriptional regulator	R4IDX0	Listeria_phage	6.3e-39	75.7
WP_009929535.1\|1014398_1014722_+	hypothetical protein	NA	NA	NA	NA
WP_009929536.1\|1014736_1014940_+	helix-turn-helix transcriptional regulator	A0A059T5F8	Listeria_phage	3.1e-28	100.0
WP_009929538.1\|1014941_1015184_+	hypothetical protein	A8ATD2	Listeria_phage	7.0e-43	98.8
WP_009929539.1\|1015186_1015372_+	hypothetical protein	A0A059T7Z3	Listeria_phage	1.7e-28	96.7
WP_009931096.1\|1015606_1015759_+	hypothetical protein	A0A059T7S2	Listeria_phage	3.4e-19	98.0
WP_165814091.1\|1015892_1016069_+	hypothetical protein	NA	NA	NA	NA
WP_026747146.1\|1016065_1016317_+	hypothetical protein	Q8W5X5	Listeria_phage	1.2e-37	96.4
WP_026747147.1\|1016345_1016621_+	hypothetical protein	A0A0B5CU46	Listeria_phage	3.0e-42	93.3
WP_026747148.1\|1016617_1017061_+	hypothetical protein	A0A2H4N816	Lake_Baikal_phage	1.5e-06	30.7
WP_026747149.1\|1017077_1017455_+	hypothetical protein	NA	NA	NA	NA
WP_010991168.1\|1017451_1017598_+	hypothetical protein	A8ATZ0	Listeria_phage	2.3e-20	97.9
WP_026747150.1\|1017613_1018012_+	hypothetical protein	R4ICD6	Listeria_phage	7.8e-39	100.0
WP_003731701.1\|1018015_1018189_+	hypothetical protein	A0A059T7N2	Listeria_phage	6.2e-25	93.0
WP_026747151.1\|1018185_1018776_+	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	3.4e-38	74.0
WP_009928027.1\|1018979_1019180_+	hypothetical protein	NA	NA	NA	NA
WP_009928026.1\|1019176_1019677_+	hypothetical protein	NA	NA	NA	NA
WP_009928025.1\|1019722_1020283_-	hypothetical protein	NA	NA	NA	NA
WP_009928024.1\|1020387_1020561_+	hypothetical protein	A0A059T5G3	Listeria_phage	8.9e-24	98.2
WP_026747152.1\|1020557_1020941_+	hypothetical protein	Q8W5W2	Listeria_phage	1.3e-59	91.3
WP_009928021.1\|1020942_1021422_+	siphovirus Gp157 family protein	A0A059T803	Listeria_phage	2.6e-57	77.2
WP_026747153.1\|1021440_1022133_+	AAA family ATPase	A8ATF0	Listeria_phage	1.1e-120	94.8
WP_026747154.1\|1022196_1023453_+	DEAD/DEAH box helicase	Q8W5V9	Listeria_phage	3.6e-231	94.7
WP_009928019.1\|1023477_1023963_+	DUF669 domain-containing protein	A0A059T5G4	Listeria_phage	2.9e-88	100.0
WP_009928017.1\|1023985_1026328_+	DNA primase	A0A059T6A4	Listeria_phage	5.5e-148	43.4
WP_009928016.1\|1026623_1026944_+	VRR-NUC domain-containing protein	Q8W5V6	Listeria_phage	4.0e-54	99.1
WP_009928015.1\|1026940_1027210_+	hypothetical protein	W0GBM0	Listeria_phage	6.9e-15	73.6
WP_026747155.1\|1027320_1027851_+	DUF3310 domain-containing protein	A0A059T7T5	Listeria_phage	1.2e-74	75.6
WP_009928014.1\|1027851_1028277_+	DUF722 domain-containing protein	Q8W5V4	Listeria_phage	2.7e-69	93.6
WP_026747156.1\|1028382_1029069_-	hypothetical protein	NA	NA	NA	NA
WP_026747157.1\|1029386_1029713_+	hypothetical protein	A0A059T5G5	Listeria_phage	2.5e-51	94.4
WP_026747158.1\|1029712_1030027_+	HNH endonuclease	A8ATF8	Listeria_phage	2.5e-56	97.1
WP_026747159.1\|1030075_1030432_+\|terminase	P27 family phage terminase small subunit	A0A059T7Y1	Listeria_phage	5.0e-45	94.9
WP_026747160.1\|1030428_1032072_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	98.9
WP_026747161.1\|1032081_1032471_-	DUF2513 domain-containing protein	A0A2I7SCV0	Paenibacillus_phage	2.8e-17	37.2
WP_026747162.1\|1032521_1033652_+\|portal	phage portal protein	A0A059T6F0	Listeria_phage	9.8e-212	98.7
WP_009928004.1\|1033648_1034365_+\|protease	Clp protease ClpP	A0A1S5SFF8	Streptococcus_phage	5.5e-67	57.4
WP_026747163.1\|1034391_1035543_+\|capsid	phage major capsid protein	A0A059T678	Listeria_phage	8.2e-214	99.7
WP_012951548.1\|1035549_1035720_+	hypothetical protein	A0A059T7Y2	Listeria_phage	6.3e-22	100.0
WP_014930914.1\|1035729_1036029_+	hypothetical protein	A0A059T7R0	Listeria_phage	5.3e-48	100.0
WP_025370587.1\|1036012_1036378_+	hypothetical protein	A0A059T6F2	Listeria_phage	2.4e-63	99.2
WP_026747164.1\|1036374_1036776_+	hypothetical protein	A8ATA2	Listeria_phage	5.2e-67	97.0
WP_026747165.1\|1036772_1037156_+	hypothetical protein	A0A059T681	Listeria_phage	2.1e-65	96.9
WP_025370590.1\|1037176_1037764_+\|tail	phage tail protein	A0A059T7Y4	Listeria_phage	1.3e-106	99.0
WP_025370591.1\|1037832_1038165_+	hypothetical protein	A0A059T7R2	Listeria_phage	8.7e-52	97.3
WP_165816498.1\|1038215_1038377_+	hypothetical protein	A0A059T6F4	Listeria_phage	5.6e-20	98.0
WP_026747166.1\|1038380_1043300_+\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	95.6
WP_026747167.1\|1043292_1044942_+\|tail	phage tail family protein	A0A059T682	Listeria_phage	0.0e+00	99.5
WP_026747168.1\|1044954_1047249_+\|tail	phage tail protein	A0A059T7Y6	Listeria_phage	0.0e+00	98.8
WP_026747169.1\|1047238_1048330_+	hypothetical protein	A0A059T7R4	Listeria_phage	1.5e-188	91.2
WP_009928178.1\|1048377_1048821_+	hypothetical protein	A0A059T6F6	Listeria_phage	6.8e-76	100.0
WP_009928179.1\|1048799_1049216_+	hypothetical protein	A0A059T5F5	Listeria_phage	9.3e-43	99.3
WP_026747170.1\|1049236_1049503_+\|holin	phage holin	A0A059T684	Listeria_phage	1.3e-37	89.8
WP_026747171.1\|1049502_1050348_+	M15 family metallopeptidase	A0A059T7Y8	Listeria_phage	2.4e-138	93.3
WP_026747172.1\|1050509_1050926_+	hypothetical protein	NA	NA	NA	NA
WP_026747173.1\|1050909_1051302_+	hypothetical protein	NA	NA	NA	NA
WP_026747174.1\|1051390_1051888_-	AP2 domain-containing protein	A8ATW6	Listeria_phage	4.5e-84	91.5
WP_012951927.1\|1051899_1052328_-	transcriptional regulator	A8ATJ2	Listeria_phage	3.9e-28	87.3
WP_012951926.1\|1052329_1052734_-	hypothetical protein	NA	NA	NA	NA
WP_003727805.1\|1052835_1053045_-	hypothetical protein	A0A059T7Z0	Listeria_phage	1.9e-28	98.6
WP_031658787.1\|1053485_1053719_+	hypothetical protein	A8ATX0	Listeria_phage	1.2e-34	93.5
1054019:1054035	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_JHUU01000017

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

87280 : 95566

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726209.1\|87280_87847_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.3e-26	36.4
WP_003726210.1\|87843_88893_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_003722245.1\|88911_90339_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_009918191.1\|90323_92543_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.5e-159	40.8
WP_003726212.1\|92535_93219_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|93222_93468_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003726214.1\|93479_94193_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.0e-40	38.3
WP_003729814.1\|94273_95566_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_KK211032

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_KK211032_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_KK211032_1

37910-38020

Orphan

Consensus_repeat	Method
AAATCAGCAGAAAAACTGCAGAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_KK211032_1

>merge|NZ_KK211032|1|37910-38020|CRISPRCasFinder
ATATTGGGATTAAATCAGCAGAAAAACTGCAGAAAAATAAGCTGATAAATAAGCTTATAACTCAATTAGTTGATGAAGCAAAAGAAAAATCAGCAGAAAAACTGCAGAAAA

>NZ_KK211032|1|1|37910-38020|CRISPRCasFinder
ATATTGGGATTAAATCAGCAGAAAA	ACTGCAGAAAAATAAGCTGATAAATAAGCTTATAACTCAATTAGTTGATGAAGCAAAAGAA
AAATCAGCAGAAAAACTGCAGAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_KK211032.1\|WP_003739618.1\|34088_34436_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_KK211032.1\|WP_026747214.1\|39295_39601_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_KK211032.1\|WP_003725109.1\|28427_28871_+\|DUF523-domain-containing-protein	unknown	unknown	gnl\|CDD\|224597
NZ_KK211032.1\|WP_003725106.1\|31159_32083_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_KK211032.1\|WP_026747212.1\|38083_38518_-\|hypothetical-protein	unknown	unknown	unknown
NZ_KK211032.1\|WP_003725108.1\|28867_30193_-\|aminopeptidase-C	unknown	unknown	gnl\|CDD\|226107
NZ_KK211032.1\|WP_026747218.1\|40564_41107_-\|hypothetical-protein	unknown	unknown	unknown
NZ_KK211032.1\|WP_026747216.1\|40000_40237_+\|hypothetical-protein	unknown	unknown	unknown
NZ_KK211032.1\|WP_009928078.1\|27435_28347_+\|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl\|CDD\|377251
NZ_KK211032.1\|WP_009928081.1\|30410_31163_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_KK211032.1\|WP_026747211.1\|34957_36316_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NZ_KK211032.1\|WP_026747215.1\|39776_39980_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NZ_KK211032.1\|WP_012951969.1\|36376_37891_-\|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225420
NZ_KK211032.1\|WP_026747210.1\|34490_34967_-\|competence-protein-ComK	unknown	unknown	gnl\|CDD\|227240
NZ_KK211032.1\|WP_026747213.1\|38532_38751_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|237756
NZ_KK211032.1\|WP_026747219.1\|41170_41950_+\|phage-antirepressor-KilAC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377029
NZ_KK211032.1\|WP_003725105.1\|32084_33983_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|182066
NZ_KK211032.1\|WP_026747220.1\|42071_42605_+\|hypothetical-protein	unknown	unknown	unknown
NZ_KK211032.1\|WP_026747217.1\|40233_40587_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367519
NZ_KK211032.1\|WP_012951966.1\|38773_39265_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368753

Protein	Function_ID	Function_description	E-value
NZ_KK211032.1\|WP_003739618.1\|34088_34436_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.28543e-16
NZ_KK211032.1\|WP_026747214.1\|39295_39601_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.82476e-17
NZ_KK211032.1\|WP_003725109.1\|28427_28871_+\|DUF523-domain-containing-protein	gnl\|CDD\|224597	COG1683, COG1683, Uncharacterized conserved protein [Function unknown].	1.0454e-65
NZ_KK211032.1\|WP_003725106.1\|31159_32083_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	3.98658e-141
NZ_KK211032.1\|WP_026747215.1\|39776_39980_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	1.03198e-15
NZ_KK211032.1\|WP_003725108.1\|28867_30193_-\|aminopeptidase-C	gnl\|CDD\|226107	COG3579, PepC, Aminopeptidase C [Amino acid transport and metabolism].	0
NZ_KK211032.1\|WP_026747219.1\|41170_41950_+\|phage-antirepressor-KilAC-domain-containing-protein	gnl\|CDD\|377029	pfam03374, ANT, Phage antirepressor protein KilAC domain. This domain was called the KilAC domain by Iyer and colleagues.	2.01299e-32
NZ_KK211032.1\|WP_026747217.1\|40233_40587_+\|hypothetical-protein	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0.00786175
NZ_KK211032.1\|WP_009928078.1\|27435_28347_+\|pseudouridine-5'-phosphate-glycosidase	gnl\|CDD\|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	0
NZ_KK211032.1\|WP_009928081.1\|30410_31163_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	7.7114e-84
NZ_KK211032.1\|WP_026747211.1\|34957_36316_-\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	2.68694e-46
NZ_KK211032.1\|WP_012951969.1\|36376_37891_-\|putative-DNA-binding-domain-containing-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	4.69562e-35
NZ_KK211032.1\|WP_026747210.1\|34490_34967_-\|competence-protein-ComK	gnl\|CDD\|227240	COG4903, ComK, Genetic competence transcription factor [Transcription].	1.99329e-65
NZ_KK211032.1\|WP_026747213.1\|38532_38751_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|237756	PRK14559, PRK14559, serine/threonine phosphatase.	0.00505933
NZ_KK211032.1\|WP_003725105.1\|32084_33983_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|182066	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional.	1.14079e-146
NZ_KK211032.1\|WP_012951966.1\|38773_39265_-\|hypothetical-protein	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00115015

>NZ_KK211032.1|WP_012951969.1|36376_37891_-|putative-DNA-binding-domain-containing-protein
MKDVNINNNLKPENSNLEYKESKNSLPKDFWKTYSAFANTKGGLVVLGVSERDNNFYLSGVNDSSKILKDLHTTLHNQNKVNYSLVNDENIKEFELMGKKIIEIHIKEAPLSKKPIYLNSDYRNTYLRSNDSDRKSTDEELRQMLRNSKDDLDSELLERFDIDDLNLNTINKYRDYLINDNVDSPYINMPVKKLLIEIGAIKRNRNSQDNDYNITLGGLLFFGKFNCITDLIPHFHLDYFNREGTNDRWIDRVATGDPNYPNLNLFEFFLIVLEKLKLTINQGFKLSEDSHRISHESNDMVITLREALANTLIHSDYMSSETVKIEHLNGYYEFSNPGEMKISIEEFVRGGNSNPRNVTITQLLRRIGFCERAGTGGPKIFDLARKNKLKFPDITTENNKTTLRVWKIDIVSAHSHLGDDEKSVLLFLTKNFLPKSFKEIQEETSLTRHKLTKVLISLEENKLIEKIGQSRATKYKLIESTEEYLTNLQHTFRKIVQFYVENDK
>NZ_KK211032.1|WP_026747211.1|34957_36316_-|recombinase-family-protein
MKAAIYIRVSTQEQIENYSIQAQTEKLTALCRSKDWDVYDIFIDGGYSGSNMNRPALNEMLSKLHEIDAVVVYRLDRLSRSQRDTITLIEEYFLKNNVEFVSLSETLDTSSPFGRAMIGILSVFAQLERETIRDRMVMGKIKRIEAGLPLTTAKGRTFGYDVIDTKLHINEEEAKQLQMIYDIFEEEKSITSLQKRLKKLGFKVKSYSSYNNWLTNDLYCGYVSYADKVHTKGVHEPIISEEQFYRVQEIFSRMGKNPNMNRDSASLLNNLVVCGKCGFGFVHRRKDTVSRGKKYHYRYYSCKTYKHTHELEKCGNKIWRADKLEELIIDRVNNYSFASRNVDKEDELDSLNEKLKIEHTKKKRLFDLYISGSYEVSELDAMMADIDAQINYYEAQIEANEELKKNKKIQENLADLATVDFDSLEFREKQLYLKSLINKIYIDGEQVTIEWL
>NZ_KK211032.1|WP_026747210.1|34490_34967_-|competence-protein-ComK
MALVACLSRLFSSSFSLVGRKEGTKHLIGVTHKPPIIIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHTLITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIMESNFPSMNRFFPPTTLAAEPRRYYSTMLPNNEDPNEPQDPEQ
>NZ_KK211032.1|WP_003739618.1|34088_34436_+|helix-turn-helix-transcriptional-regulator
MEFGEKLIHLRKKNRLTQKQLAAKIGTTASTISKYENDNHRPPIFILAKLAEILGTTTDFLLDDVAGLREKNSVNAFPLIGNPELEKWYLELPYTYSEDELLMLKRIADAIENKK
>NZ_KK211032.1|WP_003725105.1|32084_33983_+|PTS-sugar-transporter-subunit-IIA
MRITDLLSKDVMIMSLQATTKEAAIDEMIASLKSNGKINDEVLFKEAIMNREAQSSTGVGEGIAMPHAKTKAVNEPTVVFAKSEKGLDYDALDGQPAHLFFMIAAPDGANATHLETLAALSRLLVHPAFVQSLRDAKTPEEVINLFNNEQEDAEETVVAPTSTNETGKSVVAVTACPTGIAHTYMAAEKLQETANKLGVRIKVETNGSRGVENRLTDKEIAEADGVIIAADVQVDMPRFDGKHLIAKPVAAGIHKPEELIKEAISGNAPIYKAEEGSQATESADGLSIGQQIYKHLMSGVSHMLPFVIGGGIAIAIAFMLDQMLGVPQDQLAKLGSYNEIPALLKQIGDVAFGFMLPVFAGYIAYSISDRPGLVAGFVAGGVASVGGAGFLGALVGGFLAGYAVELIKLALKKLPKTLDGIKVVLFYPVLSVLIVGLLMLLLNVPMSALNTWLNDFLNSLSGTNAVILGLLLGAMMAADLGGPINKAAYIFATGTLAASVATGGSAIMAATMAAGMVPPLATFVATLIFRNKFTAQERDAGLTNSILGASFITEGAIPFAAADPLRMIPSFIAGSAITGAVVMFLNIKVLAPHGGVFVIFLVSQPWFYIIAIIIGTLISAGLIGVLRKKPTV
>NZ_KK211032.1|WP_003725106.1|31159_32083_+|1-phosphofructokinase
MIYTITLNPSIDYIVQIDQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLGGFTGNFIKDWLQNEGVKTGFVTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVMDKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMIDTTGQELLDALPNHPILIKPNHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGELKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKITKITGRN
>NZ_KK211032.1|WP_009928081.1|30410_31163_+|DeoR/GlpR-transcriptional-regulator
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVKLHNQEPSMNEKSFKNIQSKKVIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVTNGLTHIEELVRQNIDGYLLGGKMKVHTKAIIGAVALDNIQNYHFDKAFIGTNAMHPEHGYTTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFIQKTKIIEVEK
>NZ_KK211032.1|WP_003725108.1|28867_30193_-|aminopeptidase-C
MHTELTFEQLESFSRKWRENPDKLVFQASIIKNGIKAATENPASKVSIQPVFSHEVATDKVSNQQQSGRCWMFAALNTFRHKLNGTLGLKDFELSQNYTNFWDKLEKANYFLENIIETASEDEDSRLVSWLLDTPQQDGGQWDMLVSIIEKYGVVPKSAMPETFQSSKSADLNHLLNERLRTDAVILRNAIAEKKDTADLKEEMLAEVYQLLVMTLGEPPKVFDFEYRNKDNEFKQELQITPKDFYERYVDMDLKDYIPLINAPTKDKPFNQAFTVEYLGNIVNGTPIKYLNVEMDVLKKAAADQIKDGETVWFGCDVGQLSERNTGIMDTDIFLLNQTFGFKTAMTKAERLDYKHSMLTHAMVLTGVNIANGEVNRWKVENSWGEKIGNNGYFVASDAWMDEFTFQVVVHKKYLSKELIESFNQKPIVLKPWDPMGSLAL
>NZ_KK211032.1|WP_003725109.1|28427_28871_+|DUF523-domain-containing-protein
MIAVSACLAGIACRYDGKDKEITKIKQMVERGEAIPFCPEVTGGLPTPRNPAEIIGGDGKDVWLGHAKVIDNKGTDVTEEYKNGARLTLIKMQELGITQIIMKEKSPSCGSCAIYDGTFSGKIKDGTGVAAALFQMNGIKIISEFAF
>NZ_KK211032.1|WP_009928078.1|27435_28347_+|pseudouridine-5'-phosphate-glycosidase
MKNYLSLSEEVKQAKAEGKAIVALESTIISHGMPYPQNVEMARDVEQIIRDNGAVPATIALIDGKIKIGLSDEELELFAKSSNVAKVSRRDIGYLIATKQLGATTVAATMICAELAEIGIFVTGGIGGVHRGAETTMDISADLEELAKTNVAVVCAGAKSILDLNLTMEYLETKGVPVIGYQTDVLPAFYTRSSDVELTLRADAPEVIAESLKAKWDLQIKGGAVITNPIPEEFAMDEKVINDVIQTALKEAEENHIHGKDVTPFLLGKVKELTDGKSLEANIELVKHNALIGTQIAVAYQNI
>NZ_KK211032.1|WP_026747212.1|38083_38518_-|hypothetical-protein
MSKYRHLLKKWWLWVIFLLVIIGVVSLFWYTQVYTSEWGKGLSKEEKAVFEYAKETSNKSFDISSIDNKELDKLYSLIMDSGTYNKTIISDQKNLKKYSNKAYDLASKLTYVQKDFDLYKKELNKKRNLNSKAKEIMPYGLNNI
>NZ_KK211032.1|WP_026747213.1|38532_38751_-|zinc-ribbon-domain-containing-protein
MYCPKCGHALDNHENQCPNCLTPIIYQSNNNGKAQKVGEVMEESGKLMSGCGCLMTLLITIPVIVILIIMFL
>NZ_KK211032.1|WP_012951966.1|38773_39265_-|hypothetical-protein
MNKTSSELKQEFPELNFIIDNSLPTKLFGFIQNKVVHLHPSLTESELRCTIIEEAMHWKYTVGDITNFNNIDNIKQEKFARRKSHEYLVNLQTLALCYDLGYRTYYEAATFLNVTEKFLIEVVENYREKYGLMYNNGNYIIHFGSTIQVFQEDNSFYPYDYGC
>NZ_KK211032.1|WP_026747214.1|39295_39601_-|helix-turn-helix-transcriptional-regulator
MFGNRLSELRKKKGISQYKLADELGFSRGQIANYEQGSREPDYSTLLKIAEYFNVTTDYLLGKEAFDNSDLLAAHIDDDLTEDERIEIEKYLKFIRSQREE
>NZ_KK211032.1|WP_026747215.1|39776_39980_+|helix-turn-helix-transcriptional-regulator
MREKLVKLRGKRSRQDVSKDLGVTPQMLGAIERGDRTPSLNLANKIANYYNVPIEDIFFNNKDTYCV
>NZ_KK211032.1|WP_026747216.1|40000_40237_+|hypothetical-protein
MSNEELTLSIKTSQREDGSAYNAIQLGDWKVGQFVTGVHLEILGGERPKLIIECYPERIDVDGLEVEAFLKQIEEEEK
>NZ_KK211032.1|WP_026747217.1|40233_40587_+|hypothetical-protein
MNNIKQAIIKLETILENGNAIESGSFVKNSVIKNILNLLEKDQELKIIEMEVELNGVEDSIENAALLEKRLSEAKSLVEDLANTINSLEIKVNSKEEIREAEKSIKLRHFATPSTDF
>NZ_KK211032.1|WP_026747218.1|40564_41107_-|hypothetical-protein
MTKLIINEFDFSLNASNYHILNDLICVESTLNNSELNSFIELYKSHLTDEESFDFMFDNKKYYGRFGRFVFDSKGKIQLFLTIKTFVIDENTYTYSSVTRNEVEYYNTSKVLVDLEKRFNSLIDLLKKKELINEDETDIFSGYLTSYEEGIKIKTEVADLDEYLKETHETIEDIKNQYLE
>NZ_KK211032.1|WP_026747219.1|41170_41950_+|phage-antirepressor-KilAC-domain-containing-protein
MSNLQVIANDMLPVLENEKGEKFVNARELHQSLQVGKKFTTWITDKFSNYGFSKDEDYFPILGESTFGRPRTEYLLTLDTAKELAMVQNNEMGRAIRKYFIEVEKQARKLATEYPTFSYMIEDPVARAEKWIEEQQEKQEALKQLEEQKPKVVFAEAVQTSENTILVKDLATILKQKGLDIGQNRLFEWLRGSGYLLSKGAYYNKPSQKAMNLGLFEQKTHIHTDRNGLMKTTYTPQVTGKGQVYLLNKLLEEHNQVVI
>NZ_KK211032.1|WP_026747220.1|42071_42605_+|hypothetical-protein
MFQKSTSATAAMQVLAETRTQKELAIDSYVTPALISNQLRGKRTVSLEQAEQLIDSYNEPESTFMFAHEFSNGMIPPLLDGLDNHHASLTNRFELEVEEAINTLKNGLETMTYSLRKGDMLQREAAKQAISEITDVVASALTLNTSIAKAFNIDLQQVLNKRDLYYQKSGLVRSCGK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34957 : 68568

Listeria_phage(95.35%)

tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026747211.1\|34957_36316_-	recombinase family protein	Q8LTD8	Listeria_phage	5.1e-255	98.7
WP_012951969.1\|36376_37891_-	putative DNA binding domain-containing protein	NA	NA	NA	NA
WP_026747212.1\|38083_38518_-	hypothetical protein	NA	NA	NA	NA
WP_026747213.1\|38532_38751_-	zinc-ribbon domain-containing protein	A0A059T6E3	Listeria_phage	2.0e-33	97.2
WP_012951966.1\|38773_39265_-	hypothetical protein	A8ATX4	Listeria_phage	2.9e-91	99.4
WP_026747214.1\|39295_39601_-	helix-turn-helix transcriptional regulator	A0A059T669	Listeria_phage	6.8e-27	63.3
WP_026747215.1\|39776_39980_+	helix-turn-helix transcriptional regulator	A0A0B5D0D3	Listeria_phage	2.8e-08	50.0
WP_026747216.1\|40000_40237_+	hypothetical protein	A0A059T5E9	Listeria_phage	2.8e-36	97.4
WP_026747217.1\|40233_40587_+	hypothetical protein	A8ATX8	Listeria_phage	3.2e-52	98.3
WP_026747218.1\|40564_41107_-	hypothetical protein	A8ATX9	Listeria_phage	4.4e-93	98.3
WP_026747219.1\|41170_41950_+	phage antirepressor KilAC domain-containing protein	A0A0B5CTU1	Listeria_phage	4.9e-138	96.1
WP_026747220.1\|42071_42605_+	hypothetical protein	A8ATY1	Listeria_phage	1.5e-77	86.1
WP_026747221.1\|42601_42817_+	hypothetical protein	Q9T176	Listeria_phage	6.7e-29	95.8
WP_026747222.1\|42924_43113_+	hypothetical protein	Q9T175	Listeria_phage	4.5e-21	79.0
WP_026747223.1\|43333_43537_+	hypothetical protein	NA	NA	NA	NA
WP_003753535.1\|43533_44415_+	hypothetical protein	A0A2P1JTZ5	Anoxybacillus_phage	3.4e-87	58.6
WP_026747224.1\|44368_45181_+	PD-(D/E)XK nuclease-like domain-containing protein	A0A290GJV0	Caldibacillus_phage	2.1e-78	54.6
WP_026747225.1\|46092_46557_+	class I SAM-dependent methyltransferase	A0A059T693	Listeria_phage	6.9e-87	97.4
WP_176747895.1\|46553_46724_+	hypothetical protein	A8ASN5	Listeria_phage	1.4e-18	89.3
WP_049948770.1\|46770_47034_+	DUF1642 domain-containing protein	Q8W5X2	Listeria_phage	4.7e-16	58.8
WP_026747226.1\|47030_47414_+	hypothetical protein	A0A0B5CYR4	Listeria_phage	3.4e-31	54.0
WP_026747227.1\|47410_47626_+	hypothetical protein	NA	NA	NA	NA
WP_026747228.1\|47622_47832_+	hypothetical protein	A0A059T6C7	Listeria_phage	2.9e-13	60.6
WP_026747229.1\|47831_48311_+	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	5.3e-74	90.0
WP_012951948.1\|48332_48710_+	hypothetical protein	NA	NA	NA	NA
WP_031668357.1\|48737_48920_+	hypothetical protein	A8ASP6	Listeria_phage	8.5e-17	79.4
WP_026747230.1\|48864_49269_+	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	8.1e-60	87.3
WP_026747231.1\|49272_49656_+	DUF2481 family protein	A0A0B5CYS3	Listeria_phage	8.2e-62	94.5
WP_015967177.1\|49784_49949_+	hypothetical protein	A8AU02	Listeria_phage	3.9e-21	100.0
WP_026747232.1\|49967_50402_+	hypothetical protein	A8AU03	Listeria_phage	6.2e-66	87.5
WP_026747233.1\|50675_50909_+	hypothetical protein	A8AU06	Listeria_phage	1.6e-15	58.9
WP_026747234.1\|50943_51810_+\|terminase	terminase small subunit	A8ATU5	Listeria_phage	1.3e-14	70.6
WP_026747235.1\|51748_53068_+\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	1.4e-233	88.3
WP_026747236.1\|53082_54639_+	hypothetical protein	A0A0B5D0A6	Listeria_phage	1.0e-296	97.7
WP_026747237.1\|54643_55687_+	hypothetical protein	A0A0B5D111	Listeria_phage	2.0e-198	98.8
WP_026747238.1\|55782_56337_+	hypothetical protein	A8ATU9	Listeria_phage	9.7e-88	98.9
WP_026747239.1\|56359_57232_+	hypothetical protein	A8ATV0	Listeria_phage	7.4e-159	98.6
WP_176743988.1\|57245_57401_+	hypothetical protein	A0A0B5CYK6	Listeria_phage	3.4e-14	84.3
WP_026747240.1\|57401_57755_+	hypothetical protein	A8ATV2	Listeria_phage	9.9e-62	99.1
WP_026747241.1\|57754_58120_+	hypothetical protein	A8ATV3	Listeria_phage	3.3e-60	90.1
WP_026747242.1\|58109_58427_+	HK97 gp10 family phage protein	A8ATV4	Listeria_phage	8.3e-52	99.0
WP_026747243.1\|58423_58795_+	hypothetical protein	A8ATV5	Listeria_phage	5.5e-63	97.6
WP_026747244.1\|58799_59486_+	Ig domain-containing protein	A0A0B5CYK8	Listeria_phage	3.8e-110	93.9
WP_026747245.1\|59541_59973_+	hypothetical protein	A8ATV7	Listeria_phage	5.8e-72	97.9
WP_077913966.1\|59969_60281_+	hypothetical protein	A0A0B5D116	Listeria_phage	1.7e-41	96.7
WP_026747247.1\|60285_65085_+\|tail	phage tail tape measure protein	A8ATV9	Listeria_phage	0.0e+00	88.4
WP_026747248.1\|65081_66650_+\|tail	phage tail family protein	A8ATW0	Listeria_phage	5.8e-303	99.0
WP_031668358.1\|66662_68568_+\|tail	phage tail protein	A8ATW1	Listeria_phage	0.0e+00	98.6

Anti-CRISPR protein detection

Acr_ID: NZ_KK211032.1|WP_003731276.1|72195_72447_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_KK211032.1|WP_003731276.1|72195_72447_-|hypothetical-protein

72195_72447_-

83 aa aa

AcrIIA12

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3641\|WP_003731276.1\|AcrIIA12\|II-A\|Verified\|Listeria-monocytogenes	1.0	1	1.0

5. NZ_KK211034

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

100103 : 110832

Listeria_phage(40.0%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003724957.1\|100103_100832_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	1.3e-34	42.5
WP_003728205.1\|100812_101235_-\|holin	holin family protein	Q2I8E7	Bacillus_phage	8.6e-28	46.3
WP_003728206.1\|101253_101790_-	hypothetical protein	NA	NA	NA	NA
WP_003728207.1\|101786_102266_-	hypothetical protein	NA	NA	NA	NA
WP_003724953.1\|102280_102856_-	hypothetical protein	NA	NA	NA	NA
WP_003721751.1\|102870_103170_-	hypothetical protein	NA	NA	NA	NA
WP_003728209.1\|103159_104296_-\|tail	phage tail protein	A0A0B5D0G3	Listeria_phage	2.2e-46	33.8
WP_003734720.1\|104305_105124_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	5.7e-44	35.5
WP_009928420.1\|105120_106989_-	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	4.5e-20	45.8
WP_003740367.1\|106975_107380_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	8.2e-20	43.7
WP_003721745.1\|107421_107724_-	hypothetical protein	NA	NA	NA	NA
WP_003721744.1\|107771_108284_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003728212.1\|108296_108686_-	DUF5072 family protein	NA	NA	NA	NA
WP_003731177.1\|108965_109382_-	hypothetical protein	NA	NA	NA	NA
WP_009927883.1\|109393_109822_-	hypothetical protein	A8ATZ8	Listeria_phage	3.9e-12	45.7
WP_003721740.1\|110038_110374_+	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003728215.1\|110379_110832_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_JHUU01000010

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

395986 : 454572

Streptococcus_phage(15.0%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726416.1\|395986_397693_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003726415.1\|397733_398996_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003726414.1\|399009_400152_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003727496.1\|400166_400955_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003727497.1\|400968_401727_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003723450.1\|401957_402515_-	ribosome recycling factor	NA	NA	NA	NA
WP_003723449.1\|402514_403243_-	UMP kinase	NA	NA	NA	NA
WP_003727498.1\|403535_403910_+	hypothetical protein	NA	NA	NA	NA
WP_012681273.1\|403887_405093_+	helicase SNF2	L0P6E9	Lactobacillus_phage	7.0e-91	46.6
WP_003731336.1\|405082_406387_+	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	1.2e-133	52.1
WP_003726669.1\|406396_406903_+	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
WP_003726668.1\|406924_407656_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
WP_003726667.1\|407704_407944_-	YneF family protein	NA	NA	NA	NA
WP_009928628.1\|408164_410159_-	transketolase	NA	NA	NA	NA
WP_003727501.1\|410305_410533_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_026747189.1\|410626_410956_-	cell division suppressor protein YneA	NA	NA	NA	NA
WP_009928625.1\|411111_411726_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003734519.1\|411756_412281_+	GNAT family N-acetyltransferase	G9BWD5	Planktothrix_phage	3.9e-06	29.0
WP_023550496.1\|412314_413610_-	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.2e-146	62.1
WP_003723435.1\|413753_415088_-	type I glutamate--ammonia ligase	M1NM71	Moumouvirus	4.2e-12	23.8
WP_003719570.1\|415158_415527_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003727505.1\|415728_416955_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_012681271.1\|416947_418171_-	GTPase HflX	NA	NA	NA	NA
WP_003719566.1\|418281_418515_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_003726658.1\|418636_419554_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003723738.1\|419680_421357_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_026747190.1\|421589_422288_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	2.2e-12	32.4
WP_003727507.1\|422500_424387_+	peptidoglycan O-acetyltransferase OatA	B5WZU0	Pseudomonas_phage	3.8e-43	32.2
WP_023550490.1\|424419_426228_-	class 1 internalin InlK	NA	NA	NA	NA
WP_003726814.1\|426855_427323_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_010958880.1\|427405_429865_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.8
WP_003727510.1\|429861_431829_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-123	42.5
WP_003727511.1\|432009_432417_-	CoA-binding protein	NA	NA	NA	NA
WP_003726698.1\|432574_433171_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003726697.1\|433212_434085_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724130.1\|434087_434399_-	hypothetical protein	NA	NA	NA	NA
WP_023550487.1\|434421_434841_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003726695.1\|434943_435723_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003727514.1\|435743_437153_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IBU3	Erwinia_phage	4.0e-29	26.0
WP_003724001.1\|437166_437706_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_023550485.1\|437726_438629_-	tyrosine recombinase XerC	A0A1B1IQT7	uncultured_Mediterranean_phage	2.1e-23	28.0
WP_003726401.1\|438911_440216_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003727517.1\|440278_442357_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003727518.1\|442629_443490_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	3.1e-40	47.2
WP_003727519.1\|443623_444409_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003726396.1\|444405_445269_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727520.1\|445278_445821_-	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726394.1\|445922_446492_-	type I signal peptidase SipY	NA	NA	NA	NA
WP_003726393.1\|446526_447093_-	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723886.1\|447211_448471_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723884.1\|448655_449939_-	trigger factor	NA	NA	NA	NA
WP_003727521.1\|450053_450992_-	hypothetical protein	NA	NA	NA	NA
WP_003731300.1\|451253_451919_-	hypothetical protein	NA	NA	NA	NA
WP_003727523.1\|451934_452468_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003727524.1\|452591_452807_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003723563.1\|452957_453353_+	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003734523.1\|453432_454572_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_KK211033

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

113748 : 121590

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722610.1\|113748_114708_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7
WP_009918601.1\|114824_115808_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.1e-52	38.7
WP_009918600.1\|115824_116886_+	galactose mutarotase	NA	NA	NA	NA
WP_003725409.1\|116927_118658_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.5e-174	53.1
WP_003722606.1\|118765_119641_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_003731212.1\|119642_120611_+	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
WP_003725407.1\|120618_121590_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage