CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_JVSL01000027	Haemophilus parainfluenzae strain 146_HPAR 269_8915_466208_150+,...,242_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000012	Haemophilus parainfluenzae strain 146_HPAR 253_45904_1872241_43+,97+,42_, whole genome shotgun sequence	1 crisprs	cas1,cas2	1	11	1	1
NZ_JVSL01000018	Haemophilus parainfluenzae strain 146_HPAR 259_51445_2076119_83+,125+, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
NZ_JVSL01000040	Haemophilus parainfluenzae strain 146_HPAR 283_141944_5554395_177_,...,126_, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	1	0
NZ_JVSL01000034	Haemophilus parainfluenzae strain 146_HPAR 277_1917_96876_240+,123+,243_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000041	Haemophilus parainfluenzae strain 146_HPAR 284_142380_5348199_42_,...,233+, whole genome shotgun sequence	1 crisprs	DEDDh	1	3	0	0
NZ_JVSL01000015	Haemophilus parainfluenzae strain 146_HPAR 256_805_33653_55+,243+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000036	Haemophilus parainfluenzae strain 146_HPAR 279_6126_289714_242+,11+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000005	Haemophilus parainfluenzae strain 146_HPAR 229_3097_554263, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000014	Haemophilus parainfluenzae strain 146_HPAR 255_1898_446455_47+,20+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000003	Haemophilus parainfluenzae strain 146_HPAR 90_206_14922, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000013	Haemophilus parainfluenzae strain 146_HPAR 254_56103_2121718_43_,198+,43+, whole genome shotgun sequence	0 crisprs	NA	0	0	1	1
NZ_JVSL01000007	Haemophilus parainfluenzae strain 146_HPAR 245_626_30677_3+,240+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000024	Haemophilus parainfluenzae strain 146_HPAR 266_81489_3380451_131+,...,107_, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JVSL01000001	Haemophilus parainfluenzae strain 146_HPAR 25_33912_1427269, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000026	Haemophilus parainfluenzae strain 146_HPAR 268_4600_202596_136+,177_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000009	Haemophilus parainfluenzae strain 146_HPAR 248_80856_3096261_30+,...,150_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000019	Haemophilus parainfluenzae strain 146_HPAR 260_590_25931_95+,17+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000038	Haemophilus parainfluenzae strain 146_HPAR 281_44630_1985073_243+,...,70_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000010	Haemophilus parainfluenzae strain 146_HPAR 249_446_21961_34+,207+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000030	Haemophilus parainfluenzae strain 146_HPAR 273_8268_315411_235_,...,164_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000029	Haemophilus parainfluenzae strain 146_HPAR 271_64691_2483996_225+,...,150_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000037	Haemophilus parainfluenzae strain 146_HPAR 280_154570_7190935_242_,...,159+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000022	Haemophilus parainfluenzae strain 146_HPAR 264_105084_4549998_127+,...,46+, whole genome shotgun sequence	1 crisprs	cas3	5	0	0	0
NZ_JVSL01000023	Haemophilus parainfluenzae strain 146_HPAR 265_5724_205480_131+,62+,131+, whole genome shotgun sequence	0 crisprs	RT	0	0	0	0
NZ_JVSL01000031	Haemophilus parainfluenzae strain 146_HPAR 274_68401_2543542_235_,...,109+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000004	Haemophilus parainfluenzae strain 146_HPAR 193_1056_268319, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000017	Haemophilus parainfluenzae strain 146_HPAR 258_350504_14445031_61+,26+, whole genome shotgun sequence	0 crisprs	cas3	0	0	1	0
NZ_JVSL01000008	Haemophilus parainfluenzae strain 146_HPAR 247_1841_436862_20_,120+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000021	Haemophilus parainfluenzae strain 146_HPAR 262_3500_167127_113+,...,237+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000039	Haemophilus parainfluenzae strain 146_HPAR 282_55353_2398083_243_,219+,26+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000032	Haemophilus parainfluenzae strain 146_HPAR 275_152993_5447571_235_,...,12+, whole genome shotgun sequence	0 crisprs	DinG,DEDDh	0	0	0	0
NZ_JVSL01000011	Haemophilus parainfluenzae strain 146_HPAR 252_168001_6013558_43+,96+, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JVSL01000033	Haemophilus parainfluenzae strain 146_HPAR 276_100219_4239538_235_,...,223_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000006	Haemophilus parainfluenzae strain 146_HPAR 241_1710_436020_49+,111+,156+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000028	Haemophilus parainfluenzae strain 146_HPAR 270_1669_229852_223_,21+,223_, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000020	Haemophilus parainfluenzae strain 146_HPAR 261_49115_2202429_101+,...,242+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000025	Haemophilus parainfluenzae strain 146_HPAR 267_23681_1079316_131_,...,223+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000035	Haemophilus parainfluenzae strain 146_HPAR 278_2796_124054_240+,...,101+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000002	Haemophilus parainfluenzae strain 146_HPAR 44_208_10876, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JVSL01000016	Haemophilus parainfluenzae strain 146_HPAR 257_1395_52488_59+,95+, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13266 : 22096

Indivirus(16.67%)

tRNA,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049372687.1\|13266_14193_+	bifunctional riboflavin kinase/FAD synthetase	A0A1V0SD03	Indivirus	4.5e-05	30.3
WP_049372688.1\|14225_17051_+\|tRNA	isoleucine--tRNA ligase	A0A2P1ELB8	Moumouvirus	2.8e-82	27.2
WP_005699634.1\|17154_17991_-	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	1.6e-33	34.4
WP_049372689.1\|18168_18609_+	peptidoglycan-binding protein LysM	J9QDY6	Clostridium_phage	1.9e-06	32.4
WP_049369843.1\|18822_20121_+	trigger factor	NA	NA	NA	NA
WP_005695224.1\|20266_20848_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	6.9e-60	62.4
WP_005698128.1\|20857_22096_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.8e-127	57.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_JVSL01000012

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CRISPR-Cas detection and classification

Crispr_ID: NZ_JVSL01000012_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JVSL01000012_1

45077-45904

TypeII

Consensus_repeat	Method
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	PILER-CR
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CRISPRCasFinder
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CRT

12 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_JVSL01000012_1

>merge|NZ_JVSL01000012|1|45077-45904|PILER-CR,CRISPRCasFinder,CRT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACCTAACTCTATTATAAAATCAGGTTTTAGCTATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTTAGTGTTTGAGCTTCTTAAACTTTGGCGAATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACCCCAGATTGACTTGCTCTTTAACAATTTGGATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTTTTTAAAAGTAAACAAATTCGGCTTTTATATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACCTAATCACTGTGATAGCTGAGCGTGATATGATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTTAACGTGCTAGGCAGTGTGCTGACACAATATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACGGTAGTTATCTAAAAAATGAGAACATTCTAATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTCACTTAACAGAAAATCCCGGCGAGCATTTATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTTATCATAATTTACAATCTCAAGCCTTGTTATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACCGAAGTAGATGCAAGCATTGATACTTTTAAATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTCAAATCTTCGACCGTCAACAATTAGGCGTATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACGCTCACCGATACGGAAAATGGGTATTAGAAATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC

>NZ_JVSL01000012|1|1|45077-45904|PILER-CR
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CTAACTCTATTATAAAATCAGGTTTTAGCT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTAGTGTTTGAGCTTCTTAAACTTTGGCGA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CCCAGATTGACTTGCTCTTTAACAATTTGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTTTTAAAAGTAAACAAATTCGGCTTTTAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CTAATCACTGTGATAGCTGAGCGTGATATG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTAACGTGCTAGGCAGTGTGCTGACACAAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GGTAGTTATCTAAAAAATGAGAACATTCTA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCACTTAACAGAAAATCCCGGCGAGCATTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTATCATAATTTACAATCTCAAGCCTTGTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CGAAGTAGATGCAAGCATTGATACTTTTAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCAAATCTTCGACCGTCAACAATTAGGCGT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC

>NZ_JVSL01000012|1|1|45077-45904|CRISPRCasFinder
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CTAACTCTATTATAAAATCAGGTTTTAGCT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTAGTGTTTGAGCTTCTTAAACTTTGGCGA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CCCAGATTGACTTGCTCTTTAACAATTTGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTTTTAAAAGTAAACAAATTCGGCTTTTAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CTAATCACTGTGATAGCTGAGCGTGATATG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTAACGTGCTAGGCAGTGTGCTGACACAAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GGTAGTTATCTAAAAAATGAGAACATTCTA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCACTTAACAGAAAATCCCGGCGAGCATTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TTATCATAATTTACAATCTCAAGCCTTGTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CGAAGTAGATGCAAGCATTGATACTTTTAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCAAATCTTCGACCGTCAACAATTAGGCGT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC

>NZ_JVSL01000012|1|1|45077-45903|CRT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CCTAACTCTATTATAAAATCAGGTTTTAGCT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTTAGTGTTTGAGCTTCTTAAACTTTGGCGA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CCCCAGATTGACTTGCTCTTTAACAATTTGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTTTTTAAAAGTAAACAAATTCGGCTTTTAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CCTAATCACTGTGATAGCTGAGCGTGATATG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTTAACGTGCTAGGCAGTGTGCTGACACAAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CGGTAGTTATCTAAAAAATGAGAACATTCTA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTCACTTAACAGAAAATCCCGGCGAGCATTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTTATCATAATTTACAATCTCAAGCCTTGTT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CCGAAGTAGATGCAAGCATTGATACTTTTAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CTCAAATCTTCGACCGTCAACAATTAGGCGT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA	CGCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JVSL01000012.1\|WP_049372620.1\|36530_36749_+\|flagellar-FlbD-family-protein	unknown	unknown	gnl\|CDD\|377645
NZ_JVSL01000012.1\|WP_049372623.1\|37688_37931_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379410
NZ_JVSL01000012.1\|WP_049372628.1\|44688_45015_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_JVSL01000012.1\|WP_049372626.1\|40572_43722_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_JVSL01000012.1\|WP_049372624.1\|37944_38976_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NZ_JVSL01000012.1\|WP_049372622.1\|37295_37577_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JVSL01000012.1\|WP_005698823.1\|39124_39412_-\|50S-ribosomal-protein-L25	unknown	unknown	gnl\|CDD\|180318
NZ_JVSL01000012.1\|WP_049372625.1\|39638_40244_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_JVSL01000012.1\|WP_161797280.1\|36777_36945_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JVSL01000012.1\|WP_049372627.1\|43778_44696_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694

Protein	Function_ID	Function_description	E-value
NZ_JVSL01000012.1\|WP_049372620.1\|36530_36749_+\|flagellar-FlbD-family-protein	gnl\|CDD\|377645	pfam06289, FlbD, Flagellar protein (FlbD). This family consists of several bacterial FlbD flagellar proteins. The exact function of this family is unknown.	0.00504591
NZ_JVSL01000012.1\|WP_049372623.1\|37688_37931_+\|hypothetical-protein	gnl\|CDD\|379410	pfam13986, DUF4224, Domain of unknown function (DUF4224). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and viruses, and is approximately 50 amino acids in length. The protein is likely to be of phage origin and is found as protein Gp02 in the Xylella phage Xfas53.	0.00184242
NZ_JVSL01000012.1\|WP_049372628.1\|44688_45015_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.7351e-53
NZ_JVSL01000012.1\|WP_049372626.1\|40572_43722_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_JVSL01000012.1\|WP_049372624.1\|37944_38976_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	1.66997e-28
NZ_JVSL01000012.1\|WP_005698823.1\|39124_39412_-\|50S-ribosomal-protein-L25	gnl\|CDD\|180318	PRK05943, PRK05943, 50S ribosomal protein L25; Reviewed.	2.16776e-54
NZ_JVSL01000012.1\|WP_049372625.1\|39638_40244_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	4.16576e-43
NZ_JVSL01000012.1\|WP_049372627.1\|43778_44696_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	7.88387e-125

>NZ_JVSL01000012.1|WP_049372628.1|44688_45015_+|CRISPR-associated-endonuclease-Cas2
MSEEVFMRMIVLFDLPVTTKAKMRAANQFRQFLLKDGYQMLQLSIYTRIIKGRDALEKHHKRLVAHLPEEGSIRCLSITEKQFASMEILVGEKKPQEKKVNSNQLLLF
>NZ_JVSL01000012.1|WP_049372627.1|43778_44696_+|type-II-CRISPR-associated-endonuclease-Cas1
MTWRSLLISKGGKLSLHQQQMLIQQEGNEFTVPLEDIAIVVVESRETVITLPLLSAFGLYGITLLSCDEQFLPCGQWLPFNQYYRQLKTLKLQLETSLPLKKQLWQRIVQQKIRNQAKVLSLCQHQEKSERLLQLANLVKSGDKDNLEAQSAVIYFSGLFGSHFRRKEEDNAINIHLNYAYTVVRSAVARSLVLYGWLPQLGLFHHSELNAFNLADDFIEPFRPLVDLLVWNLLEKGLLTTNLTPISKQQLIKILHHQLRFNQEKVSVLTAIDKTITSLQIALIQKNATLLQLPEIDTLQEYQYE
>NZ_JVSL01000012.1|WP_049372626.1|40572_43722_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MENKNLHYILGLDLGIASVGWAVVEIDKKENPLRLIDVGVRTFERAEVPKTGESLALSRRLARSARRLTQRRVTRLKKAKRLLKSENILLSTDERLPHQVWQLRVEGLDRKLERQEWAAVLLHLIKHRGYLSQRKNESKSENKELGALLSGVASNHELLQQATYRTPAELAVKKFEVEEGHIRNQQGAYTHTFSRLDLLAEMELLFSRQQHFGNPFASEKLLENLTALLMWQKPTLSGEDILKMLGKCTFEDEYKAAKNTYTAERFVWITKLNNLRIQENGLERALSDNERLMLIEQPYEKAKLTYAQVRSILNLSDDAIFKGLRYSGEDKKAIETKTTLMEMKAYHQIRKVLEGNNLKAEWAELKANPTLLDEIGTAFSLYKTDEDISAYLAGKLSQPVLNALLENLSFDKFIQLSLKALYKLLPLMQQGLRYDEACREIYGDHYGKKTEENHHFLPQIPADEIRNPVVLRTLTQARKVINGVVRLYGSPARIHIETGREVGKSYKDRRELEKRQEENRKQRENAIKEFKEYFPHFAGEPKAKDILKMRLYKQQNAKCLYSGKPIELHRLLEKGYVEVDHALPFSRTWDDSFNNKVLVLANENQNKGNLTPFEWLDGKHNSERWRAFKALVETTAFPYAKKQRILSQKLDEKGFIERNLNDTRYVARFLCNFIADNMLLTGEGKRKVFASNGQITALLRSRWGLAKSREDNDRHHALDAVVVACSTVAMQQKITRFVRFEEGDVFTGERIDRETGEIIPLHFPTPWQFFKQEVEIRIFSDNPKLDLENSLPDRPQANHEFVQPLFVSRMPIRKMTGKAHEETLRSPKKLSEGKSIKKERLSNLKLTDLERMVNKEKEPELYQSLKEHFSKYGDYSKEKFFKKGGTEVKSIRLYKTQNKYVELNNGKTIADNGDIVRVDVFKKEKKYHAVNIYAWQVAKGILSKETSTGLFLDDNYIFQFSLFKNDLIKIPDPNNKSEYLFAYFIRPDDEPRWILKLQDNAIIPDGFSKKEKNSFRFSFKNQSFIEKYHIDELGKNINLCKRSKRQAVR
>NZ_JVSL01000012.1|WP_049372625.1|39638_40244_+|DedA-family-protein
MEFLISFFTDYGYWAVLFVLIICGFGVPIPEDITLVSGGVIAGLYPESVNSHLMLVVSMIGVLAGDSTMYWLGRIYGTRILRFRPMRKIVTLERLKMVREKFAQYGNRVLFVARFLPGLRAPIYMVSGITRRVSYTRFVLIDFCAAIISVPIWVYLGEFGAKNLDWLHEQIKKGQLVIYILIGILVLFLFWKWKKAKKQAK
>NZ_JVSL01000012.1|WP_005698823.1|39124_39412_-|50S-ribosomal-protein-L25
MAFKFNAEVRQAQGKGASRRLRHNGQIPAIIYGGSEAPVSIILNHDELNNAQAHDSFYSDVITLVVEGKEVAVKVQAMQRHPFKPKLVHIDFKRA
>NZ_JVSL01000012.1|WP_049372624.1|37944_38976_+|tyrosine-type-recombinase/integrase
MARPRKRINQGLPQGLVCRNRKRADGSIVVYYYYTMAYKKEVALGKDKHIAILEAAKLNMQYLTKKDNILFIEVLERYEKEVVPLKKAKNTRNSNIQAIKKLRQYFQDPPFTLDEIEPIHIREYLDWRKDVKPTANIEVGLFGHIWSMAREWGYTEKVSPSTGVKKFKVNYRDVYIEDYILDKIYDCATGDMKDIMDVMYLTGQRPIDVVKIHSSHIYNDLLHITQQKTGKRVAIKVIGKLKEIIEKRITDENQFLFTNKWGRKLERRSLTDYFKDTRNAASRKYKELAEEINQVQLRDLRAKAATDLSLMIDDERARKQLGHTSARTTQHYIRKEKPLNPTK
>NZ_JVSL01000012.1|WP_049372623.1|37688_37931_+|hypothetical-protein
MGREFFDEYCSPELLALITGYVCPKYQMKSLNEFGIPFLHPKGNRKFPLVLRSDGDKVLKGEKVQQITQTKERRRSAVLS
>NZ_JVSL01000012.1|WP_049372622.1|37295_37577_+|hypothetical-protein
MTELTKNDLRVGHVYSAKSPKEHGFPPLLGDRQILWMGLIYDNKEGFVDGLQYDSPSVRNGRNYPKISITKFLKWAKADITDTMPKDKWRYAR
>NZ_JVSL01000012.1|WP_161797280.1|36777_36945_+|hypothetical-protein
MIDDALYRLIMTVLISFYFILIGRKLQKLDEDRMKESEFYFRIKIWLISRGVKDV
>NZ_JVSL01000012.1|WP_049372620.1|36530_36749_+|flagellar-FlbD-family-protein
MAKFIKLTNTDESDIFINVEQIQTITKDENDTAIQFEDGTIFVKETPERIIHSIQSGGAVNVLPVVDVMTAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_JVSL01000012_1	1.12\|45839\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45839-45868	30	NZ_JVSL01000012.1	4645-4674	1	0.967

1. spacer 1.12|45839|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to position: 4645-4674, mismatch: 1, identity: 0.967

gctcaccgatacggaaaatgggtattagaa	CRISPR spacer
gctcaccgatacggcaaatgggtattagaa	Protospacer
************** ***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	847734-847764	5	0.839
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	NZ_CP045339	Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence	1075481-1075510	6	0.8
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	KY295891	Escherichia phage vB_EcoP_B, complete genome	21754-21783	6	0.8
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	MH179470	Aeromonas phage 13AhydR10PP, complete genome	36559-36588	6	0.8
NZ_JVSL01000012_1	1.9\|45641\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45641-45670	30	KU686209	Synechococcus phage S-CAM22 isolate 1209TA19, complete genome	60895-60924	6	0.8
NZ_JVSL01000012_1	1.9\|45641\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45641-45670	30	KU686208	Synechococcus phage S-CAM22 isolate 0310NB44, complete genome	60945-60974	6	0.8
NZ_JVSL01000012_1	1.9\|45641\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45641-45670	30	KU686207	Synechococcus phage S-CAM22 isolate 0210CC35, complete genome	60781-60810	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	832717-832746	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	905296-905325	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	873613-873642	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	817891-817920	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	971516-971545	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	414328-414357	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	826121-826150	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	815928-815957	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	475530-475559	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1483838-1483867	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1171161-1171190	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1077373-1077402	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	591622-591651	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	740539-740568	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	110506-110535	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1604903-1604932	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	191659-191688	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	977244-977273	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	838962-838991	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1044298-1044327	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	818662-818691	6	0.8
NZ_JVSL01000012_1	1.11\|45773\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45773-45802	30	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	905299-905328	6	0.8
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	66593-66622	7	0.767
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	48375-48404	7	0.767
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	23256-23285	7	0.767
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	21754-21783	7	0.767
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	53544-53573	7	0.767
NZ_JVSL01000012_1	1.1\|45113\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45113-45142	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	751485-751514	7	0.767
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	NC_004831	Enterobacteria phage SP6, complete genome	643-672	7	0.767
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	MG545917	Vibrio phage VEN, complete genome	886-915	7	0.767
NZ_JVSL01000012_1	1.7\|45509\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45509-45538	30	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	1243875-1243904	7	0.767
NZ_JVSL01000012_1	1.7\|45509\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45509-45538	30	MG065691	UNVERIFIED: Campylobacter phage A11a, complete genome	42882-42911	7	0.767
NZ_JVSL01000012_1	1.7\|45509\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45509-45538	30	MG065686	UNVERIFIED: Campylobacter phage A18a, complete genome	131212-131241	7	0.767
NZ_JVSL01000012_1	1.7\|45509\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45509-45538	30	NZ_KY270848	Enterococcus faecalis strain 2 plasmid pGTC2, complete sequence	38896-38925	7	0.767
NZ_JVSL01000012_1	1.15\|45244\|31\|NZ_JVSL01000012\|CRT	45244-45274	31	KY295891	Escherichia phage vB_EcoP_B, complete genome	21754-21784	7	0.774
NZ_JVSL01000012_1	1.21\|45640\|31\|NZ_JVSL01000012\|CRT	45640-45670	31	KU686209	Synechococcus phage S-CAM22 isolate 1209TA19, complete genome	60895-60925	7	0.774
NZ_JVSL01000012_1	1.21\|45640\|31\|NZ_JVSL01000012\|CRT	45640-45670	31	KU686208	Synechococcus phage S-CAM22 isolate 0310NB44, complete genome	60945-60975	7	0.774
NZ_JVSL01000012_1	1.21\|45640\|31\|NZ_JVSL01000012\|CRT	45640-45670	31	KU686207	Synechococcus phage S-CAM22 isolate 0210CC35, complete genome	60781-60811	7	0.774
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	AP018320	Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome	137580-137609	8	0.733
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	NC_047802	Pectobacterium phage PP99, complete genome	719-748	8	0.733
NZ_JVSL01000012_1	1.4\|45311\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45311-45340	30	NZ_CP032533	Bacillus megaterium NCT-2 plasmid pNCT2_5, complete sequence	41318-41347	8	0.733
NZ_JVSL01000012_1	1.4\|45311\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45311-45340	30	NZ_CP029545	Lactobacillus helsingborgensis strain ESL0183 plasmid unnamed	9290-9319	8	0.733
NZ_JVSL01000012_1	1.4\|45311\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45311-45340	30	NZ_CP009921	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence	8600-8629	8	0.733
NZ_JVSL01000012_1	1.4\|45311\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45311-45340	30	NZ_CP035095	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence	167078-167107	8	0.733
NZ_JVSL01000012_1	1.7\|45509\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45509-45538	30	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	38611-38640	8	0.733
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	66593-66623	8	0.742
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	48375-48405	8	0.742
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	23255-23285	8	0.742
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	21753-21783	8	0.742
NZ_JVSL01000012_1	1.13\|45112\|31\|NZ_JVSL01000012\|CRT	45112-45142	31	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	53544-53574	8	0.742
NZ_JVSL01000012_1	1.15\|45244\|31\|NZ_JVSL01000012\|CRT	45244-45274	31	NC_004831	Enterobacteria phage SP6, complete genome	642-672	8	0.742
NZ_JVSL01000012_1	1.15\|45244\|31\|NZ_JVSL01000012\|CRT	45244-45274	31	MH179470	Aeromonas phage 13AhydR10PP, complete genome	36558-36588	8	0.742
NZ_JVSL01000012_1	1.15\|45244\|31\|NZ_JVSL01000012\|CRT	45244-45274	31	MG545917	Vibrio phage VEN, complete genome	885-915	8	0.742
NZ_JVSL01000012_1	1.19\|45508\|31\|NZ_JVSL01000012\|CRT	45508-45538	31	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	1243874-1243904	8	0.742
NZ_JVSL01000012_1	1.19\|45508\|31\|NZ_JVSL01000012\|CRT	45508-45538	31	MG065691	UNVERIFIED: Campylobacter phage A11a, complete genome	42882-42912	8	0.742
NZ_JVSL01000012_1	1.19\|45508\|31\|NZ_JVSL01000012\|CRT	45508-45538	31	MG065686	UNVERIFIED: Campylobacter phage A18a, complete genome	131211-131241	8	0.742
NZ_JVSL01000012_1	1.19\|45508\|31\|NZ_JVSL01000012\|CRT	45508-45538	31	NZ_KY270848	Enterococcus faecalis strain 2 plasmid pGTC2, complete sequence	38895-38925	8	0.742
NZ_JVSL01000012_1	1.3\|45245\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45245-45274	30	MT050454	Vibrio anguillarum strain J360 plasmid pVaJ360_II, complete sequence	1027-1056	9	0.7
NZ_JVSL01000012_1	1.16\|45310\|31\|NZ_JVSL01000012\|CRT	45310-45340	31	NZ_CP032533	Bacillus megaterium NCT-2 plasmid pNCT2_5, complete sequence	41317-41347	9	0.71
NZ_JVSL01000012_1	1.16\|45310\|31\|NZ_JVSL01000012\|CRT	45310-45340	31	NZ_CP009921	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence	8600-8630	9	0.71
NZ_JVSL01000012_1	1.16\|45310\|31\|NZ_JVSL01000012\|CRT	45310-45340	31	NZ_CP035095	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence	167077-167107	9	0.71

1. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 5, identity: 0.839

cctaactctattataaaatcagg---ttttagct	CRISPR spacer
cctaaatcttttataaaatcaggcgctttta---	Protospacer
***** *** *************   *****

2. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP045339 (Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence) position: , mismatch: 6, identity: 0.8

cccagattgacttgctctttaacaatttgg	CRISPR spacer
gcgaaagaaacttgctctttaacaatttgg	Protospacer
 * *.*  .*********************

3. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to KY295891 (Escherichia phage vB_EcoP_B, complete genome) position: , mismatch: 6, identity: 0.8

cccagattgacttgctctttaacaatttgg	CRISPR spacer
cttatgttgccttgctctttaacaatttgc	Protospacer
*..* .*** *******************

4. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to MH179470 (Aeromonas phage 13AhydR10PP, complete genome) position: , mismatch: 6, identity: 0.8

-cccagattgacttgctctttaacaatttgg	CRISPR spacer
aattaga-tgacatgctctttaacaaattgg	Protospacer
  ..*** **** ************* ****

5. spacer 1.9|45641|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to KU686209 (Synechococcus phage S-CAM22 isolate 1209TA19, complete genome) position: , mismatch: 6, identity: 0.8

ttatcataatttacaatctcaagccttgtt	CRISPR spacer
ttatcataattaacaatcttaagaattcta	Protospacer
*********** *******.***  ** *

6. spacer 1.9|45641|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to KU686208 (Synechococcus phage S-CAM22 isolate 0310NB44, complete genome) position: , mismatch: 6, identity: 0.8

ttatcataatttacaatctcaagccttgtt	CRISPR spacer
ttatcataattaacaatcttaagaattcta	Protospacer
*********** *******.***  ** *

7. spacer 1.9|45641|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to KU686207 (Synechococcus phage S-CAM22 isolate 0210CC35, complete genome) position: , mismatch: 6, identity: 0.8

ttatcataatttacaatctcaagccttgtt	CRISPR spacer
ttatcataattaacaatcttaagaattcta	Protospacer
*********** *******.***  ** *

8. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

9. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

10. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

11. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

12. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

13. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

14. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

15. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

16. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

17. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

18. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

19. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

20. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

21. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

22. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

23. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

24. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

25. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

26. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

27. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

28. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

29. spacer 1.11|45773|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

30. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
gcaattctcttataaaatcaggttttttat	Protospacer
 .**.*** *****************   *

31. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
gcaattctcttataaaatcaggttttttat	Protospacer
 .**.*** *****************   *

32. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
gcaattctcttataaaatcaggttttttat	Protospacer
 .**.*** *****************   *

33. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
gcaattctcttataaaatcaggttttttat	Protospacer
 .**.*** *****************   *

34. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
gcaattctcttataaaatcaggttttttat	Protospacer
 .**.*** *****************   *

35. spacer 1.1|45113|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 7, identity: 0.767

ctaactctattataaaatcaggttttagct	CRISPR spacer
cttttattattttaaaatcaggttttagat	Protospacer
**  . .**** **************** *

36. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_004831 (Enterobacteria phage SP6, complete genome) position: , mismatch: 7, identity: 0.767

cccagattgacttgctctttaacaatttgg	CRISPR spacer
ctttggctgccttgctctttaacaatatgg	Protospacer
*.. *..** **************** ***

37. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to MG545917 (Vibrio phage VEN, complete genome) position: , mismatch: 7, identity: 0.767

cccagattgacttgctctttaacaatttgg	CRISPR spacer
tgaagcctgaattgctctttaacaacttgg	Protospacer
.  ** .*** **************.****

38. spacer 1.7|45509|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.767

ggtagttatctaaaaaatgagaacattcta	CRISPR spacer
actctctatttaaaaaatgagaacatccta	Protospacer
. *  .***.****************.***

39. spacer 1.7|45509|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to MG065691 (UNVERIFIED: Campylobacter phage A11a, complete genome) position: , mismatch: 7, identity: 0.767

ggtagttatctaaaaaatgagaacattcta	CRISPR spacer
cgtagttatttaaataatgagaacaggccg	Protospacer
 ********.**** **********  *..

40. spacer 1.7|45509|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to MG065686 (UNVERIFIED: Campylobacter phage A18a, complete genome) position: , mismatch: 7, identity: 0.767

ggtagttatctaaaaaatgagaacattcta	CRISPR spacer
cgtagttatttaaataatgagaacaggccg	Protospacer
 ********.**** **********  *..

41. spacer 1.7|45509|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_KY270848 (Enterococcus faecalis strain 2 plasmid pGTC2, complete sequence) position: , mismatch: 7, identity: 0.767

ggtagttatctaaaaaatgagaacattcta	CRISPR spacer
tttaactatcaaaaaaataagaacattctt	Protospacer
  **..**** *******.**********

42. spacer 1.15|45244|31|NZ_JVSL01000012|CRT matches to KY295891 (Escherichia phage vB_EcoP_B, complete genome) position: , mismatch: 7, identity: 0.774

ccccagattgacttgctctttaacaatttgg	CRISPR spacer
acttatgttgccttgctctttaacaatttgc	Protospacer
 *..* .*** *******************

43. spacer 1.21|45640|31|NZ_JVSL01000012|CRT matches to KU686209 (Synechococcus phage S-CAM22 isolate 1209TA19, complete genome) position: , mismatch: 7, identity: 0.774

cttatcataatttacaatctcaagccttgtt	CRISPR spacer
attatcataattaacaatcttaagaattcta	Protospacer
 *********** *******.***  ** *

44. spacer 1.21|45640|31|NZ_JVSL01000012|CRT matches to KU686208 (Synechococcus phage S-CAM22 isolate 0310NB44, complete genome) position: , mismatch: 7, identity: 0.774

cttatcataatttacaatctcaagccttgtt	CRISPR spacer
attatcataattaacaatcttaagaattcta	Protospacer
 *********** *******.***  ** *

45. spacer 1.21|45640|31|NZ_JVSL01000012|CRT matches to KU686207 (Synechococcus phage S-CAM22 isolate 0210CC35, complete genome) position: , mismatch: 7, identity: 0.774

cttatcataatttacaatctcaagccttgtt	CRISPR spacer
attatcataattaacaatcttaagaattcta	Protospacer
 *********** *******.***  ** *

46. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to AP018320 (Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome) position: , mismatch: 8, identity: 0.733

cccagattgacttgctctttaacaatttgg	CRISPR spacer
atcagattgacttgccctttaactttcagc	Protospacer
 .*************.*******  *. *

47. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NC_047802 (Pectobacterium phage PP99, complete genome) position: , mismatch: 8, identity: 0.733

cccagattgacttgctctttaacaatttgg	CRISPR spacer
ctagtagctacttgctctttaacaatctgg	Protospacer
*. . * . *****************.***

48. spacer 1.4|45311|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP032533 (Bacillus megaterium NCT-2 plasmid pNCT2_5, complete sequence) position: , mismatch: 8, identity: 0.733

tttttaaaagtaaacaaattcggcttttat	CRISPR spacer
ccgttaaaagtaaacatattcagcttgtgg	Protospacer
.. ************* ****.**** *.

49. spacer 1.4|45311|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP029545 (Lactobacillus helsingborgensis strain ESL0183 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tttttaaaagtaaacaaattcggcttttat	CRISPR spacer
tttttaaaagtaaacaaaatcattcctcaa	Protospacer
****************** **. ...*.*

50. spacer 1.4|45311|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP009921 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence) position: , mismatch: 8, identity: 0.733

tttttaaaagtaaacaaattcggcttttat	CRISPR spacer
ccattaaaagtaaacatattcagcttgtgg	Protospacer
.. ************* ****.**** *.

51. spacer 1.4|45311|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP035095 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tttttaaaagtaaacaaattcggcttttat	CRISPR spacer
ccattaaaagtaaacatattcagcttgtgg	Protospacer
.. ************* ****.**** *.

52. spacer 1.7|45509|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ggtagttatctaaaaaatgagaacattcta	CRISPR spacer
tctctatttctaaaaaaagagaacattctg	Protospacer
  *   * ********* ***********.

53. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 8, identity: 0.742

cctaactctattataaaatcaggttttagct	CRISPR spacer
agcaattctcttataaaatcaggttttttat	Protospacer
  .**.*** *****************   *

54. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 8, identity: 0.742

cctaactctattataaaatcaggttttagct	CRISPR spacer
agcaattctcttataaaatcaggttttttat	Protospacer
  .**.*** *****************   *

55. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

cctaactctattataaaatcaggttttagct	CRISPR spacer
agcaattctcttataaaatcaggttttttat	Protospacer
  .**.*** *****************   *

56. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

cctaactctattataaaatcaggttttagct	CRISPR spacer
agcaattctcttataaaatcaggttttttat	Protospacer
  .**.*** *****************   *

57. spacer 1.13|45112|31|NZ_JVSL01000012|CRT matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 8, identity: 0.742

cctaactctattataaaatcaggttttagct	CRISPR spacer
agcaattctcttataaaatcaggttttttat	Protospacer
  .**.*** *****************   *

58. spacer 1.15|45244|31|NZ_JVSL01000012|CRT matches to NC_004831 (Enterobacteria phage SP6, complete genome) position: , mismatch: 8, identity: 0.742

ccccagattgacttgctctttaacaatttgg	CRISPR spacer
gctttggctgccttgctctttaacaatatgg	Protospacer
 *.. *..** **************** ***

59. spacer 1.15|45244|31|NZ_JVSL01000012|CRT matches to MH179470 (Aeromonas phage 13AhydR10PP, complete genome) position: , mismatch: 8, identity: 0.742

ccccagat----tgacttgctctttaacaatttgg	CRISPR spacer
----gaattagatgacatgctctttaacaaattgg	Protospacer
    ..**    **** ************* ****

60. spacer 1.15|45244|31|NZ_JVSL01000012|CRT matches to MG545917 (Vibrio phage VEN, complete genome) position: , mismatch: 8, identity: 0.742

ccccagattgacttgctctttaacaatttgg	CRISPR spacer
gtgaagcctgaattgctctttaacaacttgg	Protospacer
 .  ** .*** **************.****

61. spacer 1.19|45508|31|NZ_JVSL01000012|CRT matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.742

cggtagttatctaaaaaatgagaacattcta	CRISPR spacer
gactctctatttaaaaaatgagaacatccta	Protospacer
 . *  .***.****************.***

62. spacer 1.19|45508|31|NZ_JVSL01000012|CRT matches to MG065691 (UNVERIFIED: Campylobacter phage A11a, complete genome) position: , mismatch: 8, identity: 0.742

cggtagttatctaaaaaatgagaacattcta	CRISPR spacer
tcgtagttatttaaataatgagaacaggccg	Protospacer
. ********.**** **********  *..

63. spacer 1.19|45508|31|NZ_JVSL01000012|CRT matches to MG065686 (UNVERIFIED: Campylobacter phage A18a, complete genome) position: , mismatch: 8, identity: 0.742

cggtagttatctaaaaaatgagaacattcta	CRISPR spacer
tcgtagttatttaaataatgagaacaggccg	Protospacer
. ********.**** **********  *..

64. spacer 1.19|45508|31|NZ_JVSL01000012|CRT matches to NZ_KY270848 (Enterococcus faecalis strain 2 plasmid pGTC2, complete sequence) position: , mismatch: 8, identity: 0.742

cggtagttatctaaaaaatgagaacattcta	CRISPR spacer
ttttaactatcaaaaaaataagaacattctt	Protospacer
.  **..**** *******.**********

65. spacer 1.3|45245|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to MT050454 (Vibrio anguillarum strain J360 plasmid pVaJ360_II, complete sequence) position: , mismatch: 9, identity: 0.7

cccagattgacttgctctttaacaatttgg	CRISPR spacer
aggaataccactcgctctttaacaatttgg	Protospacer
   *.  . ***.*****************

66. spacer 1.16|45310|31|NZ_JVSL01000012|CRT matches to NZ_CP032533 (Bacillus megaterium NCT-2 plasmid pNCT2_5, complete sequence) position: , mismatch: 9, identity: 0.71

ctttttaaaagtaaacaaattcggcttttat	CRISPR spacer
accgttaaaagtaaacatattcagcttgtgg	Protospacer
 .. ************* ****.**** *.

67. spacer 1.16|45310|31|NZ_JVSL01000012|CRT matches to NZ_CP009921 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence) position: , mismatch: 9, identity: 0.71

ctttttaaaagtaaacaaattcggcttttat	CRISPR spacer
accattaaaagtaaacatattcagcttgtgg	Protospacer
 .. ************* ****.**** *.

68. spacer 1.16|45310|31|NZ_JVSL01000012|CRT matches to NZ_CP035095 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

ctttttaaaagtaaacaaattcggcttttat	CRISPR spacer
accattaaaagtaaacatattcagcttgtgg	Protospacer
 .. ************* ****.**** *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

466 : 30977

Mannheimia_phage(15.38%)

tail,portal,terminase,capsid,protease,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049372577.1\|466_955_-	hypothetical protein	A0A0F6WCR7	Sinorhizobium_phage	1.2e-09	42.9
WP_049372578.1\|1090_1426_-	hypothetical protein	NA	NA	NA	NA
WP_049372579.1\|1489_1816_-	hypothetical protein	NA	NA	NA	NA
WP_080971286.1\|1824_6003_-	host specificity protein J	Q9FZU3	Neisseria_meningitidis_phage	1.3e-06	42.4
WP_049372580.1\|6069_6570_-\|tail	tail assembly protein	A0A0M3LQC4	Mannheimia_phage	1.1e-26	43.2
WP_049372581.1\|6587_7358_-	C40 family peptidase	A0A0M3LQI5	Mannheimia_phage	6.1e-64	49.2
WP_049372582.1\|7360_8098_-\|tail	phage minor tail protein L	A0A0P0ZD89	Stx2-converting_phage	2.8e-58	51.1
WP_049372583.1\|8098_8434_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.6e-13	34.9
WP_049372584.1\|8443_11845_-	tape measure protein	A0A0E3JPV7	Enterobacteria_phage	4.8e-68	27.8
WP_049372585.1\|11902_12166_-	hypothetical protein	NA	NA	NA	NA
WP_049372586.1\|12258_12489_-	DUF4035 domain-containing protein	NA	NA	NA	NA
WP_049372587.1\|12533_12941_-	hypothetical protein	NA	NA	NA	NA
WP_049372588.1\|13054_13708_-	hypothetical protein	NA	NA	NA	NA
WP_049372589.1\|13711_14056_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_049372590.1\|14052_14535_-	HK97 gp10 family phage protein	K7P6I1	Enterobacteria_phage	6.4e-11	26.0
WP_049372591.1\|14527_14851_-\|head	phage head closure protein	A6M954	Geobacillus_virus	2.9e-15	39.8
WP_049372592.1\|14860_15181_-\|head,tail	phage gp6-like head-tail connector protein	A0A0R6PE96	Moraxella_phage	1.3e-07	36.2
WP_049372593.1\|15227_16433_-\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	5.7e-133	61.7
WP_049372594.1\|16499_17102_-\|head,protease	HK97 family phage prohead protease	A0A1W6JP53	Morganella_phage	5.2e-79	73.0
WP_049372595.1\|17094_18309_-\|portal	phage portal protein	A0A1W6JP33	Morganella_phage	1.4e-142	61.7
WP_049372596.1\|18305_18458_-	hypothetical protein	NA	NA	NA	NA
WP_049372597.1\|18454_20161_-\|terminase	terminase large subunit	Q8HAD6	Salmonella_phage	1.4e-222	66.4
WP_049372598.1\|20157_20643_-\|terminase	phage terminase small subunit P27 family	Q6JIN1	Burkholderia_virus	2.7e-33	48.8
WP_080971287.1\|20770_21121_-	HNH endonuclease	A0A1P8DTD1	Proteus_phage	1.2e-38	62.1
WP_080971288.1\|21163_21445_-	hypothetical protein	A0A0M3LNX0	Mannheimia_phage	5.0e-08	47.2
WP_161797279.1\|21350_21629_-	DUF2570 family protein	NA	NA	NA	NA
WP_049372601.1\|21824_22406_-	lysozyme	Q1I0Z1	Pasteurella_virus	2.0e-22	34.1
WP_049372602.1\|22383_22629_-	hypothetical protein	NA	NA	NA	NA
WP_049372603.1\|22784_23159_-	hypothetical protein	NA	NA	NA	NA
WP_049372604.1\|23152_23509_-	RusA family crossover junction endodeoxyribonuclease	A0A0H5AUD2	Pseudomonas_phage	2.1e-19	51.4
WP_049372605.1\|23597_24590_-	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	8.7e-47	35.5
WP_049372606.1\|24589_25219_-	hypothetical protein	A0A0M3LS65	Mannheimia_phage	3.9e-24	33.5
WP_065420557.1\|25215_26163_-	conserved phage C-terminal domain-containing protein	A0A0P0IKQ2	Acinetobacter_phage	9.9e-16	55.1
WP_049371081.1\|26159_26855_-	phage antirepressor KilAC domain-containing protein	D0UIL6	Aggregatibacter_phage	1.9e-72	63.4
WP_049372607.1\|26905_27349_-	hypothetical protein	NA	NA	NA	NA
WP_049372608.1\|27397_27613_-	helix-turn-helix domain-containing protein	A0A0R6PH31	Moraxella_phage	2.7e-14	53.5
WP_049372609.1\|27735_28437_+	helix-turn-helix transcriptional regulator	Q7Y5W5	Haemophilus_phage	3.1e-91	70.8
WP_049372610.1\|28503_30096_+	AAA family ATPase	NA	NA	NA	NA
WP_049372611.1\|30158_30977_+	DNA adenine methylase	A0A0E3HBV2	Synechococcus_phage	2.1e-14	24.7

Anti-CRISPR protein detection

Acr_ID: NZ_JVSL01000012.1|WP_161797279.1|21350_21629_-|DUF2570-family-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_JVSL01000012.1|WP_161797279.1|21350_21629_-|DUF2570-family-protein

21350_21629_-

92 aa aa

466-30977

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_JVSL01000012_1	orTypeII	1.12\|45839\|30\|NZ_JVSL01000012\|PILER-CR,CRISPRCasFinder	45839-45868	30	4674-4645	1
NZ_JVSL01000041_1	Orphan	1.2\|105\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT,PILER-CR	105-134	30	4674-4645	1

1. spacer 1.12|45839|30|NZ_JVSL01000012|PILER-CR,CRISPRCasFinder matches to NZ_JVSL01000012 position: 4674-4645, mismatch: 1

gctcaccgatacggaaaatgggtattagaa	CRISPR spacer
gctcaccgatacggcaaatgggtattagaa	Protospacer
************** ***************

2. spacer 1.2|105|30|NZ_JVSL01000041|CRISPRCasFinder,CRT,PILER-CR matches to NZ_JVSL01000012 position: 4674-4645, mismatch: 1

gctcaccgatacggaaaatgggtattagaa	CRISPR spacer
gctcaccgatacggcaaatgggtattagaa	Protospacer
************** ***************

3. NZ_JVSL01000011

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1451 : 42641

Mannheimia_phage(45.45%)

head,capsid,holin,tail,plate,portal,terminase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049372443.1\|1451_1910_-	hypothetical protein	F6MIM0	Haemophilus_phage	4.6e-43	56.1
WP_049372444.1\|1902_2658_-	hypothetical protein	Q94MX9	Haemophilus_virus	7.9e-32	55.3
WP_049372445.1\|2667_3588_-\|tail	phage tail protein	M1TAS6	Escherichia_phage	6.9e-46	44.7
WP_049372446.1\|3588_4155_-\|tail	phage tail protein I	R9TR33	Vibrio_phage	4.0e-28	38.5
WP_049372447.1\|4147_5062_-\|plate	baseplate J/gp47 family protein	Q19UQ5	Mannheimia_phage	3.8e-73	49.0
WP_049372448.1\|5045_5396_-	GPW/gp25 family protein	Q19UQ6	Mannheimia_phage	1.6e-19	50.5
WP_049372449.1\|5395_5935_-\|plate	phage baseplate assembly protein V	A0A0M3LPY9	Mannheimia_phage	3.2e-35	52.9
WP_049372450.1\|6048_6480_-	hypothetical protein	NA	NA	NA	NA
WP_049372451.1\|6488_7046_-	hypothetical protein	NA	NA	NA	NA
WP_049372452.1\|7150_10018_-\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	1.3e-82	29.9
WP_049372453.1\|10094_10340_+	hypothetical protein	NA	NA	NA	NA
WP_049372454.1\|10349_10808_-	phage virion morphogenesis protein	A0A2H4J927	uncultured_Caudovirales_phage	9.3e-28	51.8
WP_049367474.1\|10807_11290_-\|tail	phage tail protein	F1BUP9	Erwinia_phage	1.2e-25	42.2
WP_005700162.1\|11286_11502_-	TraR/DksA family transcriptional regulator	A0A0M3LS11	Mannheimia_phage	4.8e-11	47.9
WP_080971277.1\|11498_11714_-	hypothetical protein	NA	NA	NA	NA
WP_049372455.1\|11676_12027_-	chemotaxis protein	NA	NA	NA	NA
WP_049372456.1\|12011_12530_-	lysozyme	A0A0M3LPQ1	Mannheimia_phage	2.8e-36	46.3
WP_049372457.1\|12522_12744_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_005700063.1\|12745_12955_-\|tail	tail protein X	NA	NA	NA	NA
WP_049372458.1\|12954_13461_-\|head	head completion/stabilization protein	A0A0M3LPQ0	Mannheimia_phage	7.6e-31	44.0
WP_049372459.1\|13582_14233_-\|terminase	terminase	Q19US0	Mannheimia_phage	9.1e-45	45.2
WP_049372460.1\|14238_15273_-\|capsid	phage major capsid protein, P2 family	A0A077KEQ8	Ralstonia_phage	5.6e-89	52.8
WP_049372461.1\|15294_16116_-\|capsid	GPO family capsid scaffolding protein	A0A0M3LNM2	Mannheimia_phage	4.8e-59	48.3
WP_049372462.1\|16284_18060_+\|terminase	terminase	A0A0M3LRV4	Mannheimia_phage	3.5e-216	64.5
WP_049372463.1\|18069_19080_+\|portal	phage portal protein	Q19UT6	Mannheimia_phage	9.6e-118	60.8
WP_049372464.1\|19760_20339_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_049372465.1\|20546_21512_+	hypothetical protein	NA	NA	NA	NA
WP_049372571.1\|21495_21738_+	hypothetical protein	NA	NA	NA	NA
WP_049372466.1\|21734_23519_+	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_049372467.1\|24671_25625_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049372468.1\|25761_26634_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_100066634.1\|27655_28282_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_049372470.1\|28390_28609_-	hypothetical protein	NA	NA	NA	NA
WP_049372572.1\|28739_29603_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_049371211.1\|29787_30324_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_005698533.1\|30421_31504_+	peptide chain release factor 1	G0YKC3	Acinetobacter_phage	6.2e-06	52.8
WP_049372471.1\|31503_32382_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_049372472.1\|32381_33185_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_005695859.1\|33197_34052_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	3.2e-37	36.0
WP_049372473.1\|34118_35066_+	2-hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	2.2e-23	30.7
WP_049372474.1\|35065_36247_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_049372475.1\|36250_36934_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	3.0e-38	41.0
WP_049372476.1\|36933_38184_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_049372477.1\|38244_38655_-	DUF1043 family protein	NA	NA	NA	NA
WP_049372478.1\|38745_39096_-	RidA family protein	NA	NA	NA	NA
WP_049372479.1\|39207_39924_+	YwiC-like family protein	NA	NA	NA	NA
WP_049372480.1\|39925_40600_+	sel1 repeat family protein	NA	NA	NA	NA
WP_049372481.1\|40631_42641_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_JVSL01000037

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_JVSL01000022

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_JVSL01000022_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JVSL01000022_1

39-398

Orphan

Consensus_repeat	Method
TGCNGCTGANGCTGANGAGCTTGC	CRT

8 spacers

The CRISPR arrays of NZ_JVSL01000022_1

>merge|NZ_JVSL01000022|1|39-398|CRT
TGCCGCAGATGCTGATGAGCTTGCTGCGGTTGCAGAGCTATCTGCTGCTGAAGCTGAAGAGCTTGCTGCTGTTGCAGAAGAATCTGCCGCTGACGCTGATGAGCTTGCTGCAGTCGCTGAAGAATCTGCTGCTGAAGCTGAAGAGCTTGCGGCTTTCGCTGAAGAATCTGCCGCTGAAGCTGAAGAGCTTGCTGCAGTTGCTGAGCTATCTGCTGCTGAAGCTGAAGAGCTTGCGGCTTTCGCAGAAGAATCTGCCGCTGAAGCTGAAGAGCTTGCTGCAGTCGCTGAGCTATCTGCCGCTGACGCTGATGAGCTTGCGGCTTTCGCTGAAGAATCTGCCGCAGATGCTGAAGTACTTGC

>NZ_JVSL01000022|1|1|39-398|CRT
TGCCGCAGATGCTGATGAGCTTGC	TGCGGTTGCAGAGCTATC
TGCTGCTGAAGCTGAAGAGCTTGC	TGCTGTTGCAGAAGAATC
TGCCGCTGACGCTGATGAGCTTGC	TGCAGTCGCTGAAGAATC
TGCTGCTGAAGCTGAAGAGCTTGC	GGCTTTCGCTGAAGAATC
TGCCGCTGAAGCTGAAGAGCTTGC	TGCAGTTGCTGAGCTATC
TGCTGCTGAAGCTGAAGAGCTTGC	GGCTTTCGCAGAAGAATC
TGCCGCTGAAGCTGAAGAGCTTGC	TGCAGTCGCTGAGCTATC
TGCCGCTGACGCTGATGAGCTTGC	GGCTTTCGCTGAAGAATC
TGCCGCAGATGCTGAAGTACTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JVSL01000022.1\|WP_005698907.1\|8875_9343_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|136097
NZ_JVSL01000022.1\|WP_049373001.1\|3121_4291_+\|EmrA/EmrK-family-multidrug-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|185090
NZ_JVSL01000022.1\|WP_049373007.1\|11074_11281_-\|YnbE-family-lipoprotein	unknown	unknown	gnl\|CDD\|379294
NZ_JVSL01000022.1\|WP_049373009.1\|11277_14013_-\|YdbH-family-protein	unknown	unknown	gnl\|CDD\|182654
NZ_JVSL01000022.1\|WP_049373111.1\|10506_10875_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_JVSL01000022.1\|WP_049373003.1\|5881_8713_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_JVSL01000022.1\|WP_049373005.1\|9630_10425_+\|formate/nitrite-transporter-family-protein	unknown	unknown	gnl\|CDD\|376497
NZ_JVSL01000022.1\|WP_049373002.1\|4299_5826_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_JVSL01000022.1\|WP_049373013.1\|14700_15129_-\|hypothetical-protein	unknown	unknown	unknown
NZ_JVSL01000022.1\|WP_049373011.1\|14062_14704_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_JVSL01000022.1\|WP_005698907.1\|8875_9343_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|136097	PRK06863, PRK06863, single-stranded DNA-binding protein; Provisional.	1.93317e-95
NZ_JVSL01000022.1\|WP_049373001.1\|3121_4291_+\|EmrA/EmrK-family-multidrug-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|185090	PRK15136, PRK15136, multidrug efflux MFS transporter periplasmic adaptor subunit EmrA.	1.16327e-161
NZ_JVSL01000022.1\|WP_049373007.1\|11074_11281_-\|YnbE-family-lipoprotein	gnl\|CDD\|379294	pfam13617, Lipoprotein_19, YnbE-like lipoprotein. This family includes lipoproteins similar to E. coli YnbE. Protein in this family are typically 60 amino acids in length and contain an N-terminal lipid attachment site, which has been included in the alignment to increase sensitivity. The specific function of these proteins is unknown.	0.000174141
NZ_JVSL01000022.1\|WP_049373009.1\|11277_14013_-\|YdbH-family-protein	gnl\|CDD\|182654	PRK10695, PRK10695, YdbH family protein.	0
NZ_JVSL01000022.1\|WP_049373111.1\|10506_10875_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	3.8789e-25
NZ_JVSL01000022.1\|WP_049373003.1\|5881_8713_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_JVSL01000022.1\|WP_049373005.1\|9630_10425_+\|formate/nitrite-transporter-family-protein	gnl\|CDD\|376497	pfam01226, Form_Nir_trans, Formate/nitrite transporter.	8.91008e-82
NZ_JVSL01000022.1\|WP_049373002.1\|4299_5826_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	0

>NZ_JVSL01000022.1|WP_049373001.1|3121_4291_+|EmrA/EmrK-family-multidrug-efflux-transporter-periplasmic-adaptor-subunit
MSDQQTDTQTSSNNKSQQRKKGLSIFILLLLLIAIGSATYWFFFIKGFEETEDAYVSGNQVMVSAQVAGNIAKINVDNMDPVQAGDVLLELDDTNAKLSFEQAKSNLANAVRQISQLNYTIKQLKSAVRANEITLAQAQGNLNRRVQLVKDGAIDKESFQHAKEAVELAKANLITSQNQLEANQALLLDGPLSEQPQIQSAVSNLKQAWLNLERTKIRSPIKGYVARRNAQVGQAVSVGGALMAVVTTDQMWLDANFKETQLTHMRIGQPVKIHFDLYGKDKTFDGKVVGIEMGTGSAFSLLPTQNATGNWIKVVQRVPVRIQLDPQQLAENPLRIGLSATVKVNVSDSQGETLRNQAPATTLYSTNVLQYDESAVNNLIESIIRDNSY
>NZ_JVSL01000022.1|WP_049373002.1|4299_5826_+|MFS-transporter
MSQSHFSPVQGGALVILTLALSLATFMQVLDSTIANVAIPTIAGDLGASSSQGTWVITSFGVANAISIPITGWLAKRFGEVRLFLISTLLFVLASWLCGISHSLEMLIICRVIQGAVAGPIIPLSQSLLLNNYPPKKRGMALAFWSMTVVVAPIFGPILGGWISDNIHWGWIFFINVPIGLAVVLMSWKILGDRESQISHQPIDTVGLVLLVLGVGCLQLMLDQGREQDWFNSTEIIVLTVIAVVCLIALTIWELTDDNPVVDISLFKSRNFSVGCLSTSLAFLVYLGSVVLIPLLLQQVYGYTATWAGLAAAPVGLFPILLSPIIGKLGHKIDMRILVTISFMVYALTFYWRAVTFEPGMTFADVALPQFVQGLAVACFFMPLTTITLSGLPPEKMASASSLFNFLRTLAGSVGTSLTTFMWYNREAVHHTQLTEAITPYNPISQQFFQTMASFGLNEQQTASYLAKQITAQGFIIGANEIFWLSAIIFLALFVIVWFAKPPFGNRH
>NZ_JVSL01000022.1|WP_049373003.1|5881_8713_-|excinuclease-ABC-subunit-UvrA
MDTIDIRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDSIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHDVPLTAQTISQMVDKVLSLPEESKMMLLAPVVKNRKGEHVKLLDSLAAQGYIRARIDGEICDLSDPPELALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAVVADMDDPKAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQFFDESRVVQNESISLASGAVKGWDRRNFYYYQMLTSLAKHYKFDIETPYEDLPQKIKDIVMHGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKNISNRPCADCGGSRLRPEARNVYIGNINLPQISEKSIGESLEFFQGLTLAGQKAQIAEKILKEIRERLEFLVNVGLNYLSLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIREADHIIDIGPGAGVHGGQVIAQGTAKEIMENPNSITGKFLSGEEKIEIPKKRTALDKSKLLKLKGATGNNLKGVNLEIPVGLFTCITGVSGSGKSTLINDTLFPLAQNALNRAEKTDFAPYKSIEGLEYFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPEARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFFDAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEDVAKVKGSHTARFLKDILAKG
>NZ_JVSL01000022.1|WP_005698907.1|8875_9343_+|single-stranded-DNA-binding-protein
MAGINKVIIVGNLGNDPEIRTMPNGEAVANISVATSESWTDKNTGERREVTEWHRIVLYRRLAEIAGQYLRKGSQVYVEGRLKTRKWQDNNGQDRYTTEIQGDNLQMLGGRNQEMGGYAPAQSAPQPSYQSRPAQSAPAPQAEPPMDAFDDNIPF
>NZ_JVSL01000022.1|WP_049373005.1|9630_10425_+|formate/nitrite-transporter-family-protein
MQHRDLYPHEILQDVIDKSYAKSEGHLKTLAILSFLGGGYVSFGYMAYLKVVSGIPPEWSGLSTLLGAAVFPICLICILIGGGELATGNMMMMALGRLTKRVSLKKLFRNWIVVSLGNLLGALFMAYFLGHYVGLSEGAAVAKTIAIAEAKVQMDFGRAFVSAIACNWMVCMGIWFYFGAKQTSGRILAIWFPVMIFVLIGLQHFVANMFIIPAGIFAGANVTWSQFFFNMIPVFLGNVTGGAAFVGASYLYAYRHLLKEDYCI
>NZ_JVSL01000022.1|WP_049373111.1|10506_10875_-|rhodanese-like-domain-containing-protein
MKKLLVAAISAVAITTSFVAYADVTPQAKQSMAQPEKAKGVWIDVRSAEEFNAGHLQGAVNIPHDKIIEGVKAIGSDKDAPINLYCRSGRRAEAALTELKNAGYTNVTNHGGYEDLVKKGLK
>NZ_JVSL01000022.1|WP_049373007.1|11074_11281_-|YnbE-family-lipoprotein
MIKHLKFQPHFFIFAAIFTLTACTPTIQLDTPKEGITINMNVVVDHNIKVEMDEKSQKAVGEVESAKK
>NZ_JVSL01000022.1|WP_049373009.1|11277_14013_-|YdbH-family-protein
MRKRCLWALIILLLLIVVSVGLVRVFATPKRVEQLANHFLAPHYHIELADDWQWKATGLTLPELKVKTDQCTLVNLDNTQLTWWNKRSLDVEKASLNYDCLTHLPSDNAEKTPPNLTALWAALPISDVKVKHFQLTNTEALKQAALQPFLSADWALNANYNGNQLALEAQANNDGLELHHQSTVTPRDGIFQWTGNTDIKQSGDKTYDLQFTANFEPDLSQLPQQGNVLFNWNNPELAVTKGEAKVSWQGADGQLNVQDLTANSPLLDVPFVFTKDGLDISWGKFYWTFDSYQPIKGFLGLSIHRAAEGLLPLSIDMNVILQTFGEMGKGEIVISGKNGEIGGGDDNNELDFELKTRGDLRYNSTVALTNLTYHLGGIFTHPVVYFYPGSVFKMDTVQPDTKLHVRLPLDDIIIGRYGLEGRLQATLNGTTPQFENLNLKLDGNAHEFIAGIKTVFDFRDEEHKLQSVEKQATNRWDWIINGSANWKSLNTPVKMEGKGFWEADHIELNQLSAHSKEVKMKEVKMAPLSLELKDRLRWDYEEEHIRGLLQAKTDWIELAYVGRFVSPVFGLGIDGKSISNFNFAGDLKAGSLGPLDVWGIYQNSVLSGEISWKEQSAKVFQSLFPQKWNWLIHEGSIKGQSKFVINTNGVKMGGELNLKNGKITMPDGEVYGLNIRFPMNYENEALQVASGKPIHISTKNIRYGALSVANGELDLFGRYPNTMTNPLILKNVKLSLFDGELTVPQLTFPQSKMATLSFTNIDLAQVLALAQYNQVTLTGRANATLPFWLGHKECLICNGTLEQVGNVSIKLTDEMVKGLKKGGWTENILVDLLKEMELQNSHAAVTLDPKGQMTLRASISGFNPTKRTHNPITLNYTHQENMFELWNMIDYGSQFEQNLQYKLYKQLDKDK
>NZ_JVSL01000022.1|WP_049373011.1|14062_14704_-|hypothetical-protein
MTSLACELHCLLNKKERFKFPFDKFKLPKNGIYIIFEKGESFGKMDRIVRVGTHTGENQLRSRLMQHFVKENKNRSIFRKNIGRCFLNIENQGYLDLWELDITPKEGREEKLKRIDREFEKTLEKRISQYIQTNLSFCVFEVNTKEERLFWESKITSTLSNAAKFGEIKPSENWLGNHSTKDKIRESGLWQVNELYKESLTEAELEKLLALVK
>NZ_JVSL01000022.1|WP_049373013.1|14700_15129_-|hypothetical-protein
MKKVILLSCVSKKANEKAKAKDLYLSPLFKKSLAYAYKLKPDAIYILSAKHHLLELDSVIEPYDVTLNKMKKNDRLNWGKKVIELLKWKVDLESDRFIILAGNNYILPIKDSLIHIEQPFYKMRLGERLSFLNKELEENKEE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_JVSL01000022_1	1.4\|189\|18\|NZ_JVSL01000022\|CRT	189-206	18	NZ_JVSL01000022.1	21-38	0	1.0
NZ_JVSL01000022_1	1.7\|315\|18\|NZ_JVSL01000022\|CRT	315-332	18	NZ_JVSL01000017.1	205-222	0	1.0
NZ_JVSL01000022_1	1.8\|357\|18\|NZ_JVSL01000022\|CRT	357-374	18	NZ_JVSL01000022.1	21-38	0	1.0
NZ_JVSL01000022_1	1.5\|231\|18\|NZ_JVSL01000022\|CRT	231-248	18	NZ_JVSL01000017.1	205-222	1	0.944
NZ_JVSL01000022_1	1.6\|273\|18\|NZ_JVSL01000022\|CRT	273-290	18	NZ_JVSL01000022.1	21-38	1	0.944
NZ_JVSL01000022_1	1.7\|315\|18\|NZ_JVSL01000022\|CRT	315-332	18	NZ_JVSL01000017.1	247-264	1	0.944
NZ_JVSL01000022_1	1.5\|231\|18\|NZ_JVSL01000022\|CRT	231-248	18	NZ_JVSL01000017.1	79-96	2	0.889
NZ_JVSL01000022_1	1.5\|231\|18\|NZ_JVSL01000022\|CRT	231-248	18	NZ_JVSL01000017.1	247-264	2	0.889
NZ_JVSL01000022_1	1.5\|231\|18\|NZ_JVSL01000022\|CRT	231-248	18	NZ_JVSL01000037.1	114468-114485	2	0.889

1. spacer 1.4|189|18|NZ_JVSL01000022|CRT matches to position: 21-38, mismatch: 0, identity: 1.0

ggctttcgctgaagaatc	CRISPR spacer
ggctttcgctgaagaatc	Protospacer
******************

2. spacer 1.7|315|18|NZ_JVSL01000022|CRT matches to position: 205-222, mismatch: 0, identity: 1.0

tgcagtcgctgagctatc	CRISPR spacer
tgcagtcgctgagctatc	Protospacer
******************

3. spacer 1.8|357|18|NZ_JVSL01000022|CRT matches to position: 21-38, mismatch: 0, identity: 1.0

ggctttcgctgaagaatc	CRISPR spacer
ggctttcgctgaagaatc	Protospacer
******************

4. spacer 1.5|231|18|NZ_JVSL01000022|CRT matches to position: 205-222, mismatch: 1, identity: 0.944

tgcagttgctgagctatc	CRISPR spacer
tgcagtcgctgagctatc	Protospacer
******.***********

5. spacer 1.6|273|18|NZ_JVSL01000022|CRT matches to position: 21-38, mismatch: 1, identity: 0.944

ggctttcgcagaagaatc	CRISPR spacer
ggctttcgctgaagaatc	Protospacer
********* ********

6. spacer 1.7|315|18|NZ_JVSL01000022|CRT matches to position: 247-264, mismatch: 1, identity: 0.944

tgcagtcgctgagctatc	CRISPR spacer
tgcagtcgctgagctgtc	Protospacer
***************.**

7. spacer 1.5|231|18|NZ_JVSL01000022|CRT matches to position: 79-96, mismatch: 2, identity: 0.889

tgcagttgctgagctatc	CRISPR spacer
tgctgttgctgagctgtc	Protospacer
*** ***********.**

8. spacer 1.5|231|18|NZ_JVSL01000022|CRT matches to position: 247-264, mismatch: 2, identity: 0.889

tgcagttgctgagctatc	CRISPR spacer
tgcagtcgctgagctgtc	Protospacer
******.********.**

9. spacer 1.5|231|18|NZ_JVSL01000022|CRT matches to position: 114468-114485, mismatch: 2, identity: 0.889

tgcagttgctgagctatc	CRISPR spacer
tgctgttgctgagccatc	Protospacer
*** **********.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_JVSL01000013

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1614 : 55572

Mannheimia_phage(26.92%)

tRNA,integrase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049372636.1\|1614_2409_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_049372637.1\|2474_3365_+	acetyl-CoA carboxylase, carboxyltransferase subunit beta	NA	NA	NA	NA
WP_049372638.1\|3369_4674_+	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_049372639.1\|4723_5608_-	TIGR01777 family protein	NA	NA	NA	NA
WP_005698809.1\|5607_6063_-	transcriptional regulator ArgR	NA	NA	NA	NA
WP_005698784.1\|6249_7185_+	malate dehydrogenase	NA	NA	NA	NA
WP_005698775.1\|7507_8455_-	ribose-phosphate pyrophosphokinase	A0A2K9L8D8	Tupanvirus	4.0e-41	38.6
WP_049372640.1\|8456_9380_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_005698818.1\|9379_10003_-	outer membrane lipoprotein LolB	NA	NA	NA	NA
WP_049372641.1\|10067_11312_-	multifunctional CCA addition/repair protein	A0A0F6YPT7	Sinorhizobium_phage	8.6e-92	50.0
WP_049372642.1\|11373_11982_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_049372643.1\|12050_13313_-	inorganic phosphate transporter	M4QMY4	Ostreococcus_lucimarinus_virus	2.4e-57	34.2
WP_049372644.1\|13348_14029_-	TIGR00153 family protein	NA	NA	NA	NA
WP_049372645.1\|14167_15190_+	inorganic triphosphatase	NA	NA	NA	NA
WP_049372646.1\|15216_16596_+	DNA repair protein RadA	A0A2I7QPS8	Vibrio_phage	1.8e-05	26.5
WP_005695827.1\|16678_17158_+	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_049372647.1\|17160_19950_+	DNA translocase FtsK	G1FGP1	Mycobacterium_phage	6.0e-85	47.9
WP_049365952.1\|19986_20613_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_049372648.1\|20666_22007_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	5.2e-79	39.4
WP_049368976.1\|22081_23164_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_005695832.1\|23297_24068_-	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_049372649.1\|24067_24928_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	5.8e-15	26.8
WP_049372650.1\|24911_26030_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	3.8e-30	36.6
WP_049372651.1\|26305_27541_+	peptidase T	NA	NA	NA	NA
WP_049372652.1\|27706_28336_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	3.7e-27	33.3
WP_049372653.1\|28400_28961_-	YcbK family protein	NA	NA	NA	NA
WP_049372674.1\|29036_30506_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_049372654.1\|30586_32656_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	3.8e-84	34.3
WP_049372655.1\|32684_33332_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_032822728.1\|33500_34754_+	paraquat-inducible protein A	NA	NA	NA	NA
WP_049372656.1\|34737_37395_+	PqiB family protein	NA	NA	NA	NA
WP_080971293.1\|37474_38017_-	HAD family hydrolase	A0A140XBD6	Dickeya_phage	1.3e-23	43.5
WP_049372658.1\|38019_38955_-	KpsF/GutQ family sugar isomerase	A0A2P0VNK5	Tetraselmis_virus	6.1e-42	33.3
WP_049372659.1\|39540_40608_-	DNA polymerase IV	A0A290GHP0	Caldibacillus_phage	1.5e-07	24.1
WP_049372660.1\|40717_41215_-	hypothetical protein	NA	NA	NA	NA
WP_049372661.1\|41883_43176_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1B5FPC6	Escherichia_phage	3.7e-45	33.7
WP_049367448.1\|43156_43324_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049372662.1\|43323_43836_-	MazG-like family protein	A0A0M3LTD8	Mannheimia_phage	9.7e-26	43.1
WP_049372663.1\|43810_44005_-	hypothetical protein	NA	NA	NA	NA
WP_049372664.1\|44016_44262_-	hypothetical protein	NA	NA	NA	NA
WP_049372665.1\|44269_46468_-	replication endonuclease	Q1I108	Pasteurella_virus	5.2e-177	48.2
WP_005700155.1\|46475_46784_-	hypothetical protein	NA	NA	NA	NA
WP_049367455.1\|47150_47405_-	hypothetical protein	NA	NA	NA	NA
WP_014064345.1\|47413_47773_-	hypothetical protein	NA	NA	NA	NA
WP_049372666.1\|47788_48049_-	hypothetical protein	NA	NA	NA	NA
WP_080351297.1\|48141_48384_-	hypothetical protein	Q19UN6	Mannheimia_phage	9.0e-22	68.1
WP_049372667.1\|48465_48789_-	hypothetical protein	NA	NA	NA	NA
WP_014064343.1\|48808_49021_-	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	4.8e-11	50.8
WP_049372668.1\|49139_49814_+	helix-turn-helix transcriptional regulator	A0A0M3LPF9	Mannheimia_phage	1.2e-44	43.2
WP_080971290.1\|49822_50338_+	hypothetical protein	Q19UP0	Mannheimia_phage	1.2e-42	50.6
WP_049372669.1\|50334_51072_+	hypothetical protein	NA	NA	NA	NA
WP_049372670.1\|51105_51378_+	hypothetical protein	NA	NA	NA	NA
WP_049372671.1\|51400_52594_-	phage late control D family protein	R9QBT3	Mannheimia_phage	5.9e-106	53.5
WP_005700061.1\|52593_53031_-\|tail	phage tail protein	A0A0M3LQ18	Mannheimia_phage	7.7e-40	56.0
WP_005700138.1\|53359_53506_-\|tail	GpE family phage tail protein	E5E3Q0	Burkholderia_phage	2.9e-07	65.0
WP_005700107.1\|53505_53799_-\|tail	phage tail assembly protein	E5E3Q1	Burkholderia_phage	5.4e-13	45.1
WP_005700105.1\|53877_54384_-\|tail	phage major tail tube protein	Q19UP8	Mannheimia_phage	5.8e-55	61.9
WP_049372672.1\|54387_55572_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A1S6KZY7	Salmonella_phage	3.5e-103	49.2

Anti-CRISPR protein detection

Acr_ID: NZ_JVSL01000013.1|WP_049372635.1|898_1165_-|anti-CRISPR-protein-AcrIIC4

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_JVSL01000013.1|WP_049372635.1|898_1165_-|anti-CRISPR-protein-AcrIIC4

898_1165_-

88 aa aa

AcrIIC4

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR0553\|WP_049372635.1\|AcrIIC4\|II-C\|Verified\|Haemophilus-parainfluenzae	1.0	1	1.0

NZ_JVSL01000013.1_432_855_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
NZ_JVSL01000013.1_432_855_-	WP_049372634.1	1.0	1	1.0

7. NZ_JVSL01000024

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

69144 : 77917

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049373189.1\|69144_70032_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.8e-59	46.9
WP_049373191.1\|70139_70829_-	aquaporin Z	NA	NA	NA	NA
WP_005696757.1\|71056_71374_+	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_005699815.1\|71376_71763_-	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_049356372.1\|71843_72053_+	heavy-metal-associated domain-containing protein	A0A218MNH0	uncultured_virus	6.1e-11	49.3
WP_049373194.1\|72039_74208_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.2e-186	52.1
WP_049373196.1\|74247_75651_-	envelope stress sensor histidine kinase CpxA	A0A1V0SGX0	Hokovirus	9.9e-12	25.2
WP_049373198.1\|75650_76361_-	response regulator	W8CYM9	Bacillus_phage	5.9e-29	35.3
WP_049373200.1\|76424_76838_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_049373201.1\|76900_77917_-	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	7.3e-65	41.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_JVSL01000041

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_JVSL01000041_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JVSL01000041_1

3-434

Orphan

Consensus_repeat	Method
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CRISPRCasFinder
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CRT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	PILER-CR

6 spacers

The CRISPR arrays of NZ_JVSL01000041_1

>merge|NZ_JVSL01000041|1|3-434|CRISPRCasFinder,CRT,PILER-CR
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTCAAATCTTCGACCGTCAACAATTAGGCGTATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACGCTCACCGATACGGAAAATGGGTATTAGAAATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACAAAAATCAATGCTGATACGTCAATTAGCGGATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACTCGACTGCGGGGAATATCACCTTGCCTTGCATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACCAAACAAATGGAATGCCTTTACAGCGACATATTATAGCACTGCGAAATGAAAAAGGGAGCTACAACACGGTTTGGATGGTGTGTTCTTAGCCGAGGATTATAGCACTGCGAAATGAAAAAGGGAGCTATCCC

>NZ_JVSL01000041|1|1|3-434|CRISPRCasFinder
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCAAATCTTCGACCGTCAACAATTAGGCGT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	AAAAATCAATGCTGATACGTCAATTAGCGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCGACTGCGGGGAATATCACCTTGCCTTGC
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CAAACAAATGGAATGCCTTTACAGCGACAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	ACGGTTTGGATGGTGTGTTCTTAGCCGAGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTATCCC

>NZ_JVSL01000041|1|1|3-434|CRT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCAAATCTTCGACCGTCAACAATTAGGCGT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	AAAAATCAATGCTGATACGTCAATTAGCGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCGACTGCGGGGAATATCACCTTGCCTTGC
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CAAACAAATGGAATGCCTTTACAGCGACAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	ACGGTTTGGATGGTGTGTTCTTAGCCGAGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTATCCC

>NZ_JVSL01000041|1|1|69-368|PILER-CR
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	GCTCACCGATACGGAAAATGGGTATTAGAA
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	AAAAATCAATGCTGATACGTCAATTAGCGG
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	TCGACTGCGGGGAATATCACCTTGCCTTGC
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC	CAAACAAATGGAATGCCTTTACAGCGACAT
ATTATAGCACTGCGAAATGAAAAAGGGAGCTACAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JVSL01000041.1\|WP_049373974.1\|5007_6522_+\|sodium/proline-symporter-PutP	unknown	unknown	gnl\|CDD\|273981
NZ_JVSL01000041.1\|WP_049373973.1\|3414_4890_-\|ribonuclease-G	unknown	unknown	gnl\|CDD\|183285
NZ_JVSL01000041.1\|WP_049373977.1\|10002_11034_+\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|237363
NZ_JVSL01000041.1\|WP_049373970.1\|1158_2556_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|234981
NZ_JVSL01000041.1\|WP_049373971.1\|2622_2973_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379732
NZ_JVSL01000041.1\|WP_049373976.1\|8630_9521_-\|transcriptional-regulator-GcvA	unknown	unknown	gnl\|CDD\|182990
NZ_JVSL01000041.1\|WP_049373975.1\|6521_7487_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	unknown	unknown	gnl\|CDD\|237898
NZ_JVSL01000041.1\|WP_049366163.1\|11321_11588_+\|oxaloacetate-decarboxylase-subunit-gamma	unknown	unknown	gnl\|CDD\|235086
NZ_JVSL01000041.1\|WP_049371236.1\|502_1114_-\|riboflavin-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183846
NZ_JVSL01000041.1\|WP_005698765.1\|7545_8634_-\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	unknown	unknown	gnl\|CDD\|236971

Protein	Function_ID	Function_description	E-value
NZ_JVSL01000041.1\|WP_049373974.1\|5007_6522_+\|sodium/proline-symporter-PutP	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_JVSL01000041.1\|WP_049373973.1\|3414_4890_-\|ribonuclease-G	gnl\|CDD\|183285	PRK11712, PRK11712, ribonuclease G; Provisional.	0
NZ_JVSL01000041.1\|WP_049373977.1\|10002_11034_+\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	0
NZ_JVSL01000041.1\|WP_049373970.1\|1158_2556_+\|MATE-family-efflux-transporter	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_JVSL01000041.1\|WP_049373971.1\|2622_2973_-\|hypothetical-protein	gnl\|CDD\|379732	pfam15586, Imm8, Immunity protein 8. A predicted immunity protein with an alpha+beta fold and a conserved WEa (a: aromatic) motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox7 family.	9.41551e-10
NZ_JVSL01000041.1\|WP_049373976.1\|8630_9521_-\|transcriptional-regulator-GcvA	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	8.3358e-175
NZ_JVSL01000041.1\|WP_049373975.1\|6521_7487_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	gnl\|CDD\|237898	PRK15068, PRK15068, tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB.	0
NZ_JVSL01000041.1\|WP_049366163.1\|11321_11588_+\|oxaloacetate-decarboxylase-subunit-gamma	gnl\|CDD\|235086	PRK02919, PRK02919, oxaloacetate decarboxylase subunit gamma; Provisional.	9.14109e-46
NZ_JVSL01000041.1\|WP_049371236.1\|502_1114_-\|riboflavin-synthase-subunit-alpha	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.58402e-117
NZ_JVSL01000041.1\|WP_005698765.1\|7545_8634_-\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	gnl\|CDD\|236971	PRK11760, PRK11760, putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional.	0

>NZ_JVSL01000041.1|WP_049371236.1|502_1114_-|riboflavin-synthase-subunit-alpha
MFTGIVQGIAQIYAIKDSDNFRTQIVKLPAEMRKGLEIGASVANNGVCLTVTEIHDDLVSFDLMQETLRITNLGSLKAGDFVNIERAMQMGAEIGGHILSGHVYCTASVSQIIESENNRQVWFKLPTKDVMKYILTKGFIAIDGISLTIGEVKDDEFCVNLIPETLHRTLIGKRQIGDLVNIEIDPQTQAIVDTVERYLAAKA
>NZ_JVSL01000041.1|WP_049373970.1|1158_2556_+|MATE-family-efflux-transporter
MNSRLFSQYRIDIQKLIRIATPIGLAQLAQTGMGTVDVIMAGRVSSADVGGVGIGASIWLPLVLFGQGLLLALPPTISYLNGSGQRHRIAHQVRQGLWISFLVMIPLALIIYHNDFILQFMNMDAHMADVTMNYLRAMVWGLPAYLLLINFRCLNDGIAKTKPAMVITFMGLMLNIPLNYMFIYGKFGAPALGGVGCGVATAIVNWAMAILMITYSAKNYNERSLKVFEKIIEKPDIKTLKKLAALGLPIAIALCSEVSLFALSSLLLSPLGADVVASHQIALNTSAVAFMFPMSIAMAATILVAQELGNHAPQKAKIMSYAAIMLGLIAASVLALVIWVFSAEIATLIVGDNATVIALSSSLLAIAAIYQFSDSVQVVVSGILRGYKDTKIILYITLLAYWGVGIPVGYILSRTDWIVPSIGAKGFWVAFIIALTIAAALLFIRMRKIQSQSDEAIIQQLERLK
>NZ_JVSL01000041.1|WP_049373971.1|2622_2973_-|hypothetical-protein
MLIADLKWIDYGFSMRDEASLLVLKPAYCLNLTLAIGTKGNSGSDYFYTNVFNVGMVQREKVLVINKGMVVALKTLDDIENYLSLMINSISGETWDDIVIQLQKYFDWEYEGYREV
>NZ_JVSL01000041.1|WP_049373973.1|3414_4890_-|ribonuclease-G
MDSVELLMNVTPNETRVALVETGVLKEVHIERQAKRGIVGNIYKGRVTRVLPGMQSAFVDIGLEKAAFLHASDIVSHTECVDVNEQKQFRAKSISELVREGQDIVVQVVKDPLGTKGARLTTDITLPSRYLVFMPENSHVGVSQRIESEEERARLKALVEPFCDELGGFIIRTATEGATEEELHQDAEFLKRLWRKVLERKGKYPTRSKIYGEPALPQRILRDFIGANLEKIHIDSKLCFNEVKEFTDEFMPELSEKLMLYTGSQPIFDIYGVERGIQNALEKRVNLKSGGYLIIEQTEAMTTIDINTGAFVGHRNLDETIFNTNIEATKAIAQQLQLRNLGGIIIIDFIDMQTDEHRNRVIESLEEALSKDRVKTNVNGFTQLGLVEMTRKRTRESLEHVLCDECPTCQGRGRVKTVETVCYEIMREIIRVNHLFSSEQFVVYASPAVADYLIKEESHGLLPEIEMFISKQVQVKTEQYYNQEQFDVVVM
>NZ_JVSL01000041.1|WP_049373974.1|5007_6522_+|sodium/proline-symporter-PutP
MFGLDPTLITFSIYIFGMILIGVLAYYYTNNLSDYILGGRKLGSFVTAMSAGASDMSGWLLMGLPGAVYVSGLVEGWIAIGLILGAYFNWLLVAGRLRIYTEFNNNALTLPEYFHHRFGTSHNLLKIVSATIILAFFTIYCASGVVAGAKLFQNLFSVDYSTAIWYGALATIVYTFIGGFLAVSWTDTIQATLMIFALILTPLFIFLSLGDASQFTEVLHQAESAANKDFTDLFSSTTPLGLLSLAAWGLGYFGQPHILARFMAAYSVKSLIKARRISMTWMVICLAGAIGIGFFGIPYFFANPNVAGVVNNEPEQVFIELAKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDFYKGFIRPKASEKELVWLGRAMVLVIAGIAIWIAQDENSKVLKLVEFAWAGFGSAFGPVVLFSLFWKRMTSSAAMAGMVVGAVVVFAWKSVIPETSEWFNVYEMIPGFILASLAIIVVSLLSAEPENEVKETFEKAEKAYKEAK
>NZ_JVSL01000041.1|WP_049373975.1|6521_7487_+|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB
MIDFRPFYQQIATTNLSAWLETLPLQLKEWEKQTHGDYAKWSKIVDFLPDLQADTIDLKNAVKSDCTIPLSEGEKQRIIHHLKQLMPWRKGPYHLFDIHVDCEWRSDFKWDRVLPHLAPLKDRTILDVGCGSGYHMWRMVGEGAKMVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEEMQPLAAFDTVFSMGVLYHRKSPLDHLTQLKNQLVKGGELVLETLVVDGDVNTVLVPSDRYAKMKNVYFIPSVAALINWLKKVGFTNVRCVDVATTTLEEQRKTDWLENESLIDFLDPNDHSKTIEGYQAPTRAVILANK
>NZ_JVSL01000041.1|WP_005698765.1|7545_8634_-|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM
MNKLALYCRIGFEKEVAAEITDRASERGVFGFARVVENSGYVIFECYQPGDADRLAREIPFNRLIFARQMIVVSDLLENLDPQDRISPILAQYERIAEDINLKQAVELFVETADTNEAKELSTFCRKFTVPLRQALKKKGWLQGKPNAKRGQILHCFFTQPNCCYVGYSYLGNNSTHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRNEESKRLNENMVGVDLGACPGGWTYQLVKRGLFVYAVDHGKMAASLHDTGRIEHCPEDGFKFQPPKRKHIDWLVCDMVEQPSRIANLIGKWLINGWCRETIFNLKLPMKKRYQEVMLCLENLAVMLAEKELEFDIQAKHLYHDREEITVHIALK
>NZ_JVSL01000041.1|WP_049373976.1|8630_9521_-|transcriptional-regulator-GcvA
MYKRLPPLNSLKSFESAARHLSFTKAADELFVTQAAVSHQIKLLEDFLGVELFIRKNRSLELTEFGKAYFVDINKVLRKLNEATERLLTLKAEPHLAISVPQTFGIQWLVPHLSDFNKQHPEIEVRLKGVDQDEGLLNKEIDIAIYYGKGDWENLQVDRLGEENLVILAAPSLLEKIPVRCPDDLKKHTLIHTHTRDNWQAMADYLKLDDLNIQQGPLFSHTFMALQAAVHGQGIALANRILAQQEIENGHLQIVLPTELRDPKSFYVVNHLDRLDDEQIQAFRTWIKDSIKLGKI
>NZ_JVSL01000041.1|WP_049373977.1|10002_11034_+|branched-chain-amino-acid-aminotransferase
MKDLDWNNLGFSYIKTDYRFIAHWKDGKWDEGKLTTDNMLHIHEGSTAIHYGQQCFEGLKAYRCKDGSINLFRPDQNAKRMQHTSDRLLMPQVPTELFIRACKEVVKANQEWLGPYGSGATLYLRPFLFGTGANIGVKTAPEFIFSVFCCPVGAYFKGGLAPSNFITTDYDRAAPMGTGGVKVGGNYAASLLPHELAAEQGTPERKFADAIYLDPKTHTKIEEVGAANFFGITKDNKFITPASDSILPSITKYSLLHIAKERLGMEAIEGDVYIDQLDQFAEAGACGTAAVITPVGGIQHKGKFHVFYSETEVGPVTRKLYNELTGIQFGDVEAPEGWIVKVE
>NZ_JVSL01000041.1|WP_049366163.1|11321_11588_+|oxaloacetate-decarboxylase-subunit-gamma
MTPSALIGEGINLMFSGMGFVLVFLLILIWAIGLMSKLINRFFPEPQPEPKTSQNSTALSAAPTDDFERLRPVIAAAIAHHRRTQQFK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_JVSL01000041_1	1.2\|105\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT,PILER-CR	105-134	30	NZ_JVSL01000012.1	4645-4674	1	0.967

1. spacer 1.2|105|30|NZ_JVSL01000041|CRISPRCasFinder,CRT,PILER-CR matches to position: 4645-4674, mismatch: 1, identity: 0.967

gctcaccgatacggaaaatgggtattagaa	CRISPR spacer
gctcaccgatacggcaaatgggtattagaa	Protospacer
************** ***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	832717-832746	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	905296-905325	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	873613-873642	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	817891-817920	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	971516-971545	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	414328-414357	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	826121-826150	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	815928-815957	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	475530-475559	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1483838-1483867	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1171161-1171190	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1077373-1077402	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	591622-591651	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	740539-740568	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	110506-110535	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1604903-1604932	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	191659-191688	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	977244-977273	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	838962-838991	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1044298-1044327	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	818662-818691	6	0.8
NZ_JVSL01000041_1	1.1\|39\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	39-68	30	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	905299-905328	6	0.8
NZ_JVSL01000041_1	1.6\|369\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	369-398	30	MN484599	Streptomyces phage Wipeout, complete genome	117073-117102	6	0.8
NZ_JVSL01000041_1	1.6\|369\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	369-398	30	MH590599	Streptomyces phage Karimac, complete genome	116273-116302	6	0.8
NZ_JVSL01000041_1	1.6\|369\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT	369-398	30	MN369750	Streptomyces phage TomSawyer, complete genome	118121-118150	6	0.8
NZ_JVSL01000041_1	1.3\|171\|30\|NZ_JVSL01000041\|CRISPRCasFinder,CRT,PILER-CR	171-200	30	NC_010945	Streptococcus phage PH15, complete genome	7957-7986	7	0.767

1. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

2. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

3. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

4. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

5. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

6. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

7. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

8. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

9. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

10. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

11. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

12. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

13. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

14. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

15. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

16. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

17. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

18. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

19. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

20. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

21. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
cgaaatcttcgaccgtcatcaatacgggcg-	Protospacer
. **************** **** ..****

22. spacer 1.1|39|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.8

tcaaatcttcgaccgtcaacaat-taggcgt	CRISPR spacer
ggaaatcttcgaccgtcatcaatacgggcg-	Protospacer
  **************** **** ..****

23. spacer 1.6|369|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to MN484599 (Streptomyces phage Wipeout, complete genome) position: , mismatch: 6, identity: 0.8

acggt-ttggatggtgtgttcttagccgagg	CRISPR spacer
-tgctattggatggtgtgttccttgccgacg	Protospacer
 .* * ***************.* ***** *

24. spacer 1.6|369|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to MH590599 (Streptomyces phage Karimac, complete genome) position: , mismatch: 6, identity: 0.8

acggt-ttggatggtgtgttcttagccgagg	CRISPR spacer
-tgctattggatggtgtgttccttgccgacg	Protospacer
 .* * ***************.* ***** *

25. spacer 1.6|369|30|NZ_JVSL01000041|CRISPRCasFinder,CRT matches to MN369750 (Streptomyces phage TomSawyer, complete genome) position: , mismatch: 6, identity: 0.8

acggt-ttggatggtgtgttcttagccgagg	CRISPR spacer
-tgctattggatggtgtgttccttgccgacg	Protospacer
 .* * ***************.* ***** *

26. spacer 1.3|171|30|NZ_JVSL01000041|CRISPRCasFinder,CRT,PILER-CR matches to NC_010945 (Streptococcus phage PH15, complete genome) position: , mismatch: 7, identity: 0.767

aaaaatcaatgctgatacgtcaattagcgg--	CRISPR spacer
accaatcaatgctgatacgccaat--gttgtt	Protospacer
*  ****************.****  *. *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_JVSL01000040

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

63727 : 71849

Aureococcus_anophage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049373909.1\|63727_64681_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	7.3e-59	42.9
WP_049373910.1\|64799_66560_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	7.0e-23	23.7
WP_049373911.1\|66559_68290_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A076FI99	Aureococcus_anophage	1.2e-14	23.5
WP_005696501.1\|68542_69010_+	anaerobic ribonucleoside-triphosphate reductase-activating protein	A0A2H5BH04	Vibrio_virus	6.5e-53	60.3
WP_049373912.1\|69006_69795_-	TatD family hydrolase	NA	NA	NA	NA
WP_005699853.1\|69852_70362_-	peptidylprolyl isomerase	A0A076FI46	Aureococcus_anophage	1.0e-11	32.5
WP_049373913.1\|70469_71849_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	1.7e-53	29.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage