CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CUEW01000070	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000098	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000076	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	WYL	0	0	0
NZ_CUEW01000007	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000011	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000110	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000071	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000029	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000068	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000082	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000018	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	cas3	0	0	0
NZ_CUEW01000040	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	WYL	0	0	0
NZ_CUEW01000039	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000092	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000061	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000024	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000004	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	csa3	0	0	0
NZ_CUEW01000028	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000062	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000012	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000077	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000081	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000051	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000067	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000097	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000044	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000099	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000033	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000096	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000093	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000063	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000107	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000086	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000074	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000056	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000052	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000042	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	cas3	0	0	0
NZ_CUEW01000043	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000038	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000088	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000083	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	WYL	0	0	0
NZ_CUEW01000053	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000045	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000054	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000066	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000021	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000080	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000016	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000069	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	csa3	0	0	0
NZ_CUEW01000055	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000025	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000095	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000017	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000094	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000037	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000049	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000019	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0
NZ_CUEW01000047	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000091	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000087	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000057	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000112	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000008	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000090	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000079	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000060	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000036	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000108	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000010	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000102	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000035	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000111	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000104	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000005	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000014	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	csa3	0	0	0
NZ_CUEW01000034	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000085	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000048	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000003	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000027	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000041	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	csa3	0	0	0
NZ_CUEW01000050	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000109	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000065	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000031	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000022	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	DinG	0	0	0
NZ_CUEW01000064	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000059	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000072	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000046	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000023	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000089	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000002	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	cas3,DEDDh	0	1	1
NZ_CUEW01000001	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000015	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000106	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000073	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000009	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000105	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000006	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	csa3	0	0	0
NZ_CUEW01000100	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000030	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000013	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	1 crisprs	NA	1	0	0
NZ_CUEW01000020	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	cas3	0	0	0
NZ_CUEW01000078	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000032	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000075	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000101	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000084	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000058	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CUEW01000026	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CUEW01000103	Staphylococcus haemolyticus strain CN1134, whole genome shotgun sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

89594 : 130510

Staphylococcus_phage(70.83%)

integrase,tail,terminase,capsid,plate,protease,holin,portal,head

attL 84603:84618|attR 130924:130939

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
84603:84618	attL	NA	NA	NA	NA
WP_011275888.1\|89594_89954_-	hypothetical protein	A0A1J0MFV1	Staphylococcus_phage	9.2e-23	44.8
WP_123955565.1\|90048_90792_-	hypothetical protein	Q4ZE35	Staphylococcus_virus	4.1e-73	61.6
WP_002457563.1\|91416_91629_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	6.4e-16	62.3
WP_033080034.1\|92012_92744_-	hypothetical protein	NA	NA	NA	NA
WP_033080033.1\|92750_93524_-	hypothetical protein	Q4ZAU0	Staphylococcus_virus	5.6e-49	41.0
WP_049426043.1\|93705_94623_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6JNM6	Staphylococcus_phage	5.6e-64	61.0
WP_033080057.1\|94669_95053_-\|holin	phage holin family protein	A8D3R9	Staphylococcus_phage	1.1e-16	37.8
WP_049426044.1\|95115_96393_-\|plate	BppU family phage baseplate upper protein	A0A1J0MFQ3	Staphylococcus_phage	4.0e-137	57.4
WP_049426045.1\|96410_97439_-	SGNH/GDSL hydrolase family protein	Q8LTH0	Staphylococcus_virus	6.6e-98	55.5
WP_049426046.1\|97449_98031_-	hypothetical protein	A0A1J0MFH9	Staphylococcus_phage	5.9e-27	50.0
WP_033080028.1\|98011_98230_-	hypothetical protein	A0A1J0MF94	Staphylococcus_phage	1.8e-05	69.4
WP_049426048.1\|99396_100224_-\|tail	phage tail family protein	A0A2I6PDE7	Staphylococcus_phage	1.2e-97	60.4
WP_049426049.1\|100223_106172_-\|tail	phage tail tape measure protein	A0A2I6PDS2	Staphylococcus_phage	0.0e+00	54.5
WP_033080024.1\|106413_106755_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	2.8e-37	70.3
WP_033080023.1\|106798_107029_-	hypothetical protein	W5RA14	Staphylococcus_phage	7.7e-07	37.8
WP_033080022.1\|107044_107800_-\|tail	tail protein	A0A2K9VBP7	Staphylococcus_phage	1.2e-85	70.6
WP_033080021.1\|107839_108235_-	hypothetical protein	A0A0K1LKC0	Staphylococcus_phage	2.7e-39	58.0
WP_046309306.1\|108231_108639_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	5.0e-33	57.1
WP_049426050.1\|108635_108968_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	2.7e-29	55.0
WP_049426051.1\|108977_109256_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	6.2e-27	63.0
WP_049426052.1\|109326_110481_-\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	1.8e-152	71.0
WP_033080016.1\|110493_111213_-\|protease	Clp protease ClpP	M1TAZ4	Staphylococcus_phage	1.6e-87	66.9
WP_100479691.1\|111169_112435_-\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	6.1e-194	79.9
WP_033080015.1\|112439_114131_-\|terminase	terminase large subunit	M9QX14	Staphylococcus_phage	1.9e-288	84.2
WP_033080014.1\|114120_114429_-\|terminase	terminase	A0A2I6PEQ6	Staphylococcus_phage	7.1e-40	81.4
WP_033080013.1\|114568_114883_-	HNH endonuclease	A0A2I6PDC4	Staphylococcus_phage	8.9e-38	72.9
WP_033080012.1\|115034_115469_-	transcriptional regulator	A7TWI7	Staphylococcus_phage	1.2e-56	76.9
WP_033080011.1\|115690_116269_-	hypothetical protein	NA	NA	NA	NA
WP_033080010.1\|116315_116780_-	hypothetical protein	NA	NA	NA	NA
WP_033080009.1\|116884_117373_+	hypothetical protein	NA	NA	NA	NA
WP_033080008.1\|117375_117720_-	hypothetical protein	A0A2H4JG35	uncultured_Caudovirales_phage	1.4e-44	82.6
WP_052064761.1\|117720_117978_-	hypothetical protein	A0A0D4DCJ8	Staphylococcus_phage	2.5e-30	87.0
WP_033080006.1\|118158_118623_-	hypothetical protein	A0A1W6JNM3	Staphylococcus_phage	4.9e-85	100.0
WP_080291055.1\|119061_119382_-	DUF3310 domain-containing protein	A0A1W6JQJ4	Staphylococcus_phage	5.5e-43	76.8
WP_033080005.1\|119510_119735_-	hypothetical protein	A0A2H4JE91	uncultured_Caudovirales_phage	5.8e-07	43.8
WP_033080004.1\|119718_119904_-	hypothetical protein	A0A2H4JG42	uncultured_Caudovirales_phage	1.8e-14	71.4
WP_033080003.1\|119904_120309_-	RusA family crossover junction endodeoxyribonuclease	A0A2H4J5E6	uncultured_Caudovirales_phage	1.2e-55	79.5
WP_033080002.1\|120321_120567_-	hypothetical protein	H9A0Z5	Staphylococcus_phage	4.1e-30	73.8
WP_033080001.1\|120544_120766_-	hypothetical protein	A0A0D4DD53	Staphylococcus_phage	3.0e-24	76.4
WP_033080000.1\|120762_121998_-	AAA family ATPase	A0A0D4DCV8	Staphylococcus_phage	2.4e-195	85.2
WP_033079999.1\|121990_122350_-	hypothetical protein	A0A0D4DCI3	Staphylococcus_phage	1.3e-45	74.8
WP_033079998.1\|122349_123081_-	DnaD domain protein	A0A2H4J5K2	uncultured_Caudovirales_phage	1.8e-57	57.4
WP_033079997.1\|123077_123317_-	helix-turn-helix transcriptional regulator	A0A2H4J5H7	uncultured_Caudovirales_phage	4.1e-27	77.3
WP_049425991.1\|123769_124120_-	single-stranded DNA-binding protein	Q4ZAD5	Staphylococcus_virus	1.5e-41	74.5
WP_033079995.1\|124374_124638_-	hypothetical protein	A0A1W6JP63	Staphylococcus_phage	1.2e-16	51.8
WP_033079994.1\|124706_124886_-	hypothetical protein	A0A2H4JAZ6	uncultured_Caudovirales_phage	1.6e-07	59.3
WP_033079993.1\|124898_125177_-	hypothetical protein	NA	NA	NA	NA
WP_033079992.1\|125200_125395_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	6.5e-23	87.5
WP_033079991.1\|125659_125992_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	1.1e-51	89.1
WP_033079990.1\|126004_126679_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	3.2e-85	67.9
WP_033079989.1\|126724_127834_+	3'-5' exonuclease	G3MAD3	Bacillus_virus	4.3e-10	28.4
WP_033079988.1\|127901_129026_+\|integrase	site-specific integrase	S5MBZ0	Brevibacillus_phage	7.3e-42	31.3
WP_011275890.1\|129169_130510_-	type I glutamate--ammonia ligase	A0A2L2DJT4	Acanthamoeba_polyphaga_mimivirus	8.5e-13	25.9
130924:130939	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CUEW01000049

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 15716

uncultured_Caudovirales_phage(75.0%)

portal,capsid,head,tail,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154393743.1\|0_5246_-\|tail	phage tail tape measure protein	A0A2H4J8X5	uncultured_Caudovirales_phage	0.0e+00	97.4
WP_017175428.1\|5342_5498_-	hypothetical protein	A0A2H4J5B6	uncultured_Caudovirales_phage	1.3e-21	98.0
WP_011276043.1\|5545_5908_-	hypothetical protein	A0A2H4J5B3	uncultured_Caudovirales_phage	9.5e-60	100.0
WP_053018015.1\|6150_6792_-\|tail	phage tail protein	A0A2H4JAV6	uncultured_Caudovirales_phage	4.0e-109	93.9
WP_037540964.1\|6792_7200_-	hypothetical protein	A0A2H4JBV0	uncultured_Caudovirales_phage	6.7e-70	99.3
WP_011276047.1\|7196_7619_-	hypothetical protein	A0A2H4J781	uncultured_Caudovirales_phage	9.4e-75	100.0
WP_011276048.1\|7608_7980_-\|head,tail	head-tail adaptor protein	A0A2H4J5E7	uncultured_Caudovirales_phage	1.7e-67	99.2
WP_011276049.1\|7969_8266_-	hypothetical protein	A0A2H4JFZ6	uncultured_Caudovirales_phage	2.8e-49	99.0
WP_053020760.1\|8283_9462_-\|capsid	phage major capsid protein	A0A2H4J5D0	uncultured_Caudovirales_phage	4.6e-220	99.7
WP_053020759.1\|9524_10391_-\|protease	Clp protease ClpP	A0A2H4J8Y7	uncultured_Caudovirales_phage	1.5e-135	91.3
WP_053020758.1\|10383_11529_-\|portal	phage portal protein	A0A2H4J5C5	uncultured_Caudovirales_phage	1.3e-211	97.4
WP_053038144.1\|11548_13210_-\|terminase	terminase large subunit	A0A2H4J5C2	uncultured_Caudovirales_phage	0.0e+00	99.5
WP_048668029.1\|13206_13566_-	hypothetical protein	A0A2H4JD45	uncultured_Caudovirales_phage	1.8e-58	100.0
WP_053020756.1\|13771_14098_-	HNH endonuclease	A0A2H4JAW8	uncultured_Caudovirales_phage	8.3e-55	96.3
WP_053020755.1\|14218_14665_-	transcriptional regulator	A0A2H4JIA3	uncultured_Caudovirales_phage	3.5e-80	98.6
WP_053020754.1\|14677_14866_-	DUF1514 domain-containing protein	A0A0D4DCK3	Staphylococcus_phage	3.7e-23	98.4
WP_053020753.1\|14867_15098_-	hypothetical protein	A0A1W6JQ62	Staphylococcus_phage	2.3e-11	46.7
WP_053023445.1\|15097_15265_-	transcriptional regulator	H9A0T9	Staphylococcus_phage	1.4e-18	81.8
WP_049426284.1\|15270_15501_-	DUF1381 domain-containing protein	A0A0D4DC76	Staphylococcus_phage	3.3e-18	98.7
WP_011276064.1\|15497_15716_-	hypothetical protein	A0A0D4DD65	Staphylococcus_phage	7.8e-33	97.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CUEW01000065

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

160 : 9980

Staphylococcus_phage(73.68%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049396929.1\|160_676_-	hypothetical protein	A0A0D4DCT6	Staphylococcus_phage	4.3e-90	99.4
WP_049396932.1\|690_1407_-	helix-turn-helix transcriptional regulator	A0A0D4DD29	Staphylococcus_phage	5.4e-131	99.2
WP_016064915.1\|1541_1811_+	helix-turn-helix transcriptional regulator	H9A0Y0	Staphylococcus_phage	1.0e-42	100.0
WP_049396941.1\|1826_2600_+	Rha family transcriptional regulator	A1BTY9	Staphylococcus_virus	1.8e-116	84.0
WP_049396944.1\|2716_2908_-	hypothetical protein	NA	NA	NA	NA
WP_053015879.1\|2963_3284_+	DUF771 domain-containing protein	A0A0D4DD43	Staphylococcus_phage	9.3e-51	91.5
WP_053015880.1\|3280_3475_+	hypothetical protein	A0A2H4JAZ6	uncultured_Caudovirales_phage	3.2e-22	89.1
WP_037570343.1\|3536_3791_+	hypothetical protein	H9A0R3	Staphylococcus_phage	2.0e-16	72.9
WP_037570342.1\|3783_4320_+	hypothetical protein	A0A0H3U480	Staphylococcus_phage	9.1e-67	74.0
WP_053015881.1\|4320_5109_+	ATP-binding protein	Q4ZBM5	Staphylococcus_phage	1.0e-135	95.4
WP_053015882.1\|5137_5665_+	hypothetical protein	A9CR64	Staphylococcus_phage	3.9e-62	72.0
WP_053015883.1\|5679_6351_+	hypothetical protein	A9CR65	Staphylococcus_phage	1.5e-106	79.3
WP_048668080.1\|6347_6578_+	helix-turn-helix transcriptional regulator	A0A1W6JNL6	Staphylococcus_phage	2.6e-31	89.5
WP_053015884.1\|6584_7352_+	replication protein	A0A1W6JNI1	Staphylococcus_phage	1.2e-141	99.2
WP_053015885.1\|7364_8135_+	ATP-binding protein	A0A2H4JAY9	uncultured_Caudovirales_phage	4.4e-139	98.0
WP_053015907.1\|8282_8525_+	hypothetical protein	A0A1W6JNF3	Staphylococcus_phage	1.4e-38	98.8
WP_011276631.1\|8535_8940_+	RusA family crossover junction endodeoxyribonuclease	A0A2H4J5E6	uncultured_Caudovirales_phage	1.4e-72	100.0
WP_053015886.1\|8939_9134_+	hypothetical protein	A0A1W6JNG1	Staphylococcus_phage	2.9e-31	98.4
WP_117276922.1\|9277_9508_+	hypothetical protein	A0A2H4JE91	uncultured_Caudovirales_phage	6.7e-19	94.6
WP_080366940.1\|9590_9980_+	DUF3310 domain-containing protein	A0A1W6JNJ7	Staphylococcus_phage	2.1e-68	99.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CUEW01000005

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

73180 : 94127

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011275466.1\|73180_79651_-	YSIRK signal domain/LPXTG anchor domain surface protein	A0A2H4PQU6	Staphylococcus_phage	1.3e-05	27.4
WP_011275465.1\|79877_80189_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	3.7e-36	72.8
WP_011275464.1\|80209_82624_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	86.2
WP_011275463.1\|82922_84110_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.9e-179	79.2
WP_011275462.1\|84220_85180_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.0e-68	85.4
WP_011275461.1\|85176_85737_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	3.3e-75	72.4
WP_016931327.1\|85876_86278_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011275459.1\|86746_87574_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_011275458.1\|87799_88801_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.5e-134	71.2
WP_011275457.1\|88852_89311_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.8e-59	85.3
WP_011275456.1\|89322_90504_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	4.7e-172	73.5
WP_011275455.1\|90519_91152_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-79	68.1
WP_011275454.1\|91158_92202_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.2e-128	62.4
WP_037571131.1\|92636_94127_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	9.8e-18	80.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CUEW01000047

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

156 : 14736

Staphylococcus_phage(93.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011275451.1\|156_1008_-	autolysin	A0A1J0MFB0	Staphylococcus_phage	1.0e-35	36.9
WP_011275450.1\|1215_1437_-	hypothetical protein	NA	NA	NA	NA
WP_011275449.1\|1693_2170_+	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	3.6e-30	47.4
WP_011275448.1\|2171_2618_+	competence protein ComK	NA	NA	NA	NA
WP_011275447.1\|2601_3072_-	membrane protein	A0A2H4PQT8	Staphylococcus_phage	1.7e-16	41.2
WP_011275446.1\|3292_4006_-	transaldolase	M1PR54	Cyanophage	5.0e-20	35.0
WP_011275445.1\|4269_4575_+	hypothetical protein	NA	NA	NA	NA
WP_011275444.1\|4667_5033_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.9e-34	59.3
WP_053015865.1\|5029_5383_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.2e-05	30.8
WP_053015866.1\|5447_6284_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.0e-122	74.4
WP_016931383.1\|6562_7471_-	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	1.3e-108	80.2
WP_046309189.1\|7564_8761_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.5e-197	87.2
WP_011275438.1\|9151_10744_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	4.7e-276	87.0
WP_011275437.1\|10808_11579_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	4.3e-94	67.1
WP_011275436.1\|11559_12033_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	2.9e-48	57.7
WP_011275435.1\|12099_12336_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	6.4e-33	75.9
WP_011275434.1\|12332_13340_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.0e-98	52.9
WP_011275433.1\|13341_14736_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-169	62.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_CUEW01000029

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

344 : 19880

Staphylococcus_phage(62.96%)

integrase

attL 1435:1449|attR 23387:23401

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048668103.1\|344_767_-	dUTP diphosphatase	A0A1W6JQI5	Staphylococcus_phage	2.9e-68	96.4
WP_048668102.1\|766_988_-	hypothetical protein	NA	NA	NA	NA
WP_048668101.1\|971_1223_-	hypothetical protein	NA	NA	NA	NA
WP_080363992.1\|1215_1482_-	hypothetical protein	A0A2H4J2H1	uncultured_Caudovirales_phage	1.7e-21	83.1
1435:1449	attL	NA	NA	NA	NA
WP_053038128.1\|1535_1946_-	hypothetical protein	W5RVA2	Staphylococcus_phage	6.6e-49	68.1
WP_053015890.1\|1932_2130_-	hypothetical protein	A0A1W6JNI7	Staphylococcus_phage	6.1e-29	100.0
WP_053015889.1\|2126_2591_-	hypothetical protein	A0A2H4J7A0	uncultured_Caudovirales_phage	5.4e-84	98.1
WP_053038129.1\|3026_3251_-	hypothetical protein	A0A1W6JQG7	Staphylococcus_phage	3.5e-20	97.3
WP_053015886.1\|3400_3595_-	hypothetical protein	A0A1W6JNG1	Staphylococcus_phage	2.9e-31	98.4
WP_053038130.1\|3597_3909_-	VRR-NUC domain-containing protein	A0A2H4JHE0	uncultured_Caudovirales_phage	2.2e-49	95.1
WP_053038131.1\|4180_6493_-	DNA primase	A0A2H4JB92	uncultured_Caudovirales_phage	0.0e+00	98.1
WP_053038132.1\|6470_7016_-	DUF669 domain-containing protein	A0A1W6JQH6	Staphylococcus_phage	8.6e-97	96.1
WP_080365571.1\|8421_9006_-	hypothetical protein	E5DV63	Deep-sea_thermophilic_phage	4.4e-30	43.6
WP_053020742.1\|8992_9688_-	AAA family ATPase	A0A2H4JHD3	uncultured_Caudovirales_phage	6.0e-127	96.1
WP_053020741.1\|9687_10173_-	siphovirus Gp157 family protein	A0A2H4JD18	uncultured_Caudovirales_phage	3.2e-50	64.6
WP_053020740.1\|10156_10396_-	hypothetical protein	A0A1W6JND7	Staphylococcus_phage	3.7e-28	83.1
WP_053020739.1\|10450_10642_-	DUF1270 family protein	A0A1W6JND6	Staphylococcus_phage	2.1e-21	87.3
WP_049395065.1\|10654_10867_-	hypothetical protein	A0A1W6JNG8	Staphylococcus_phage	2.7e-30	97.1
WP_011276644.1\|10926_11139_+	hypothetical protein	W5R9J5	Staphylococcus_phage	1.3e-05	42.3
WP_053020738.1\|11310_12102_-	antirepressor	A0A2H4J5J5	uncultured_Caudovirales_phage	5.4e-116	79.8
WP_053018059.1\|12101_12296_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	2.5e-22	87.5
WP_037570348.1\|12548_12887_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	1.4e-33	61.8
WP_053020737.1\|12899_13571_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	1.3e-46	47.1
WP_037570354.1\|13582_13930_+	hypothetical protein	NA	NA	NA	NA
WP_037570356.1\|14219_15230_+	hypothetical protein	A0A1S5SFA1	Streptococcus_phage	7.6e-22	28.8
WP_053020725.1\|15555_16605_+\|integrase	site-specific integrase	A0A1W6JNC2	Staphylococcus_phage	2.4e-196	99.7
WP_080365813.1\|17127_18840_-	CHAP domain-containing protein	A0A1W6JQL2	Staphylococcus_phage	0.0e+00	91.9
WP_053020766.1\|18836_19136_-	hypothetical protein	A0A0D4DCQ8	Staphylococcus_phage	1.3e-43	99.0
WP_053020765.1\|19273_19570_-	DUF2951 family protein	A0A2H4JAA6	uncultured_Caudovirales_phage	1.6e-33	85.7
WP_053020764.1\|19580_19880_-	hypothetical protein	A0A0D4DBZ1	Staphylococcus_phage	6.4e-46	98.0
23387:23401	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_CUEW01000013

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CUEW01000013_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CUEW01000013_1

18835-18921

Orphan

Consensus_repeat	Method
CCCAGCAAAGAGAATTTCACATGGAAATTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CUEW01000013_1

>merge|NZ_CUEW01000013|1|18835-18921|CRISPRCasFinder
CCCAGCAAAGAGAATTTCACATGGAAATTCCACAAGCAAAGCAGGCTGGGGTTGGGGCCCAGCAGAGAGAATTTCACATGGAAATTC

>NZ_CUEW01000013|1|1|18835-18921|CRISPRCasFinder
CCCAGCAAAGAGAATTTCACATGGAAATTC	CACAAGCAAAGCAGGCTGGGGTTGGGG
CCCAGCAGAGAGAATTTCACATGGAAATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CUEW01000013.1\|WP_053015823.1\|9155_9680_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CUEW01000013.1\|WP_011276255.1\|7017_8349_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CUEW01000013.1\|WP_011276241.1\|27731_27926_-\|YjzD-family-protein	unknown	unknown	gnl\|CDD\|371396
NZ_CUEW01000013.1\|WP_011276257.1\|4106_5489_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CUEW01000013.1\|WP_033079768.1\|30403_30781_-\|DUF3899-domain-containing-protein	unknown	unknown	gnl\|CDD\|372441
NZ_CUEW01000013.1\|WP_033079774.1\|5481_6684_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CUEW01000013.1\|WP_011276244.1\|21945_22254_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NZ_CUEW01000013.1\|WP_016931172.1\|20920_21745_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_CUEW01000013.1\|WP_033079773.1\|10429_13918_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CUEW01000013.1\|WP_016931167.1\|8578_9151_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CUEW01000013.1\|WP_011276247.1\|19041_19443_+\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NZ_CUEW01000013.1\|WP_037570611.1\|19516_20839_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
NZ_CUEW01000013.1\|WP_016931169.1\|13910_17588_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CUEW01000013.1\|WP_016931170.1\|17713_18619_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CUEW01000013.1\|WP_016931174.1\|28131_29073_+\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_CUEW01000013.1\|WP_011276258.1\|2956_3919_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CUEW01000013.1\|WP_011276252.1\|9694_10267_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CUEW01000013.1\|WP_053015824.1\|24821_27431_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CUEW01000013.1\|WP_016931175.1\|29086_30331_+\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NZ_CUEW01000013.1\|WP_011276243.1\|22700_24527_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748

Protein	Function_ID	Function_description	E-value
NZ_CUEW01000013.1\|WP_053015823.1\|9155_9680_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.29652e-33
NZ_CUEW01000013.1\|WP_011276255.1\|7017_8349_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CUEW01000013.1\|WP_011276241.1\|27731_27926_-\|YjzD-family-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	3.7724e-11
NZ_CUEW01000013.1\|WP_011276257.1\|4106_5489_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CUEW01000013.1\|WP_033079768.1\|30403_30781_-\|DUF3899-domain-containing-protein	gnl\|CDD\|372441	pfam13038, DUF3899, Domain of unknown function (DUF3899). Putative Tryptophanyl-tRNA synthetase.	5.68363e-13
NZ_CUEW01000013.1\|WP_033079774.1\|5481_6684_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CUEW01000013.1\|WP_011276244.1\|21945_22254_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	5.04644e-41
NZ_CUEW01000013.1\|WP_016931172.1\|20920_21745_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.2792e-77
NZ_CUEW01000013.1\|WP_033079773.1\|10429_13918_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CUEW01000013.1\|WP_016931167.1\|8578_9151_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.23065e-27
NZ_CUEW01000013.1\|WP_011276247.1\|19041_19443_+\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	9.78366e-34
NZ_CUEW01000013.1\|WP_037570611.1\|19516_20839_-\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
NZ_CUEW01000013.1\|WP_016931169.1\|13910_17588_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CUEW01000013.1\|WP_016931170.1\|17713_18619_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	3.73716e-87
NZ_CUEW01000013.1\|WP_016931174.1\|28131_29073_+\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0
NZ_CUEW01000013.1\|WP_011276258.1\|2956_3919_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	1.28079e-136
NZ_CUEW01000013.1\|WP_011276252.1\|9694_10267_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.60968e-52
NZ_CUEW01000013.1\|WP_053015824.1\|24821_27431_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CUEW01000013.1\|WP_016931175.1\|29086_30331_+\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_CUEW01000013.1\|WP_011276243.1\|22700_24527_+\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	2.63283e-79

>NZ_CUEW01000013.1|WP_016931170.1|17713_18619_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFNYKDAESYGVKVKREDAVWDLKKVFAEFGEGDFHPQTLLEGLQQNQTLDFQEQVRKAVVAAEDSGKADEFKIAFNDIEFLPPVTPPNNVIAFGRNYQDHASELNHEVQRLYVFTKAASSLTGDESTIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYIYGYTIINDITDRNAQNEQDQAFLSKSLTGGCPMGPYIVTKDELPTPENVNIVTKVNNDIRQDGNTSQMINKIDDLIEEISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTTYIAKD
>NZ_CUEW01000013.1|WP_016931169.1|13910_17588_+|helicase-exonuclease-AddAB-subunit-AddA
MNNIPIKPKDAQWTDAQWKSIYANGQDILVAAAAGSGKTAVLVERIIQKIIRDEIDVDKLLVVTFTNLSAREMKHRVDQRIQQASIENPNNEHLKNQRIKIHQAQISTLHSFCLKIIQQHYDVIDLDPNFRTISDVENVLLLEQSIDEVLEKHYDTPDIEFLTLVEQLSSDRNDDNFRDLLKRFYNFSIANPSPFEWLDSLVEIYTDDNKHKLYLDELERLSKIYIKAAYHTLLEAENNFLNCIEAEKHLDVIKLEKFKCEKMIEGNVINFEEIINYTSEKLPTITKKLKDTNEDEGISSQFLTNAKDFYDDYKKLLSEVKNKYLMRSYEDLKVDMKRLAPRIQYLVQIVKDIINGFAEKKRSRNVLDFSDYEHFALQILTDQEGNASPIAKEYRSQFEEILVDEYQDTNQVQEAIISKIKRGDESNGNLFMVGDVKQSIYKFRQADPTLFMDKYHRFTKDGDQSGLRIDLSKNFRSRKEVLATTNYLFDHMMDEEVGEIEYDADARLYFGATKYSDKSMPLELHALIQDKSSDNDLEKSEQEARYIAEQVKYIIEHKQVYDMKSETYRQATFKDIVILERGLKNARNLQQVFKDYNIPFHVNSKEGYFEQTEVRLVLSFLRTVDNPLQDIYLVGLMRSVIYQFTEDELANIRVQSMNDDYFYQSILHYMKDQEANPLLVEKLEHFMDDINMYQEYSQSHPVYQLIDKFYNDHYVIQYFSGLIGGKGRRANLYGLFNKAVEFENSSFRGLYQFIRFIDELIERNKDFGEENVIGPNDNVVRMMTVHSSKGLEFPYVIYSELSKNFNKGDLRKPLILNQKYGLGIDYFDLEQNVTYPSLSSVVIKSITEKELISEEMRLMYVALTRAKEQLILIGTIDKEETLEKLERLPISGNQIALHKRLSADRPFDLIYSILAKYQSTSLLPEYQFEKSIDNLDESLRPTVDIKIAQFEELSIEDSESEQESRNISDLEVEGSHDDTLKQQINDQLSFKYPYLKDTEKPSKQSVSELKRQLETEESGTSYERVRQYRIGVSTYERPKFLRENKKRKANEIGTLMHTVMQHLPFKETRMTETELNDYINELIEKHIIEEDAKKDIQFEAVMNFIRSDLYMTITQADKVYRELPFVVNQARVDEMPESDEDVSIIQGMIDLIFLKDDQYYFVDYKTDAFNKRRGMTDEEVGIQLRDKYKIQMKYYKNTLETILNSKVYGYLYFFQFGQMSIEEDV
>NZ_CUEW01000013.1|WP_033079773.1|10429_13918_+|helicase-exonuclease-AddAB-subunit-AddB
MELNAYIGRAGTGKSHHMIDNIKQQMKEDPLGDPIVLIAPTQSTFQLEQAFVNDKELNGSLRTEVLHFERLSYRVFQEVGGLTEERLTQAATEMMIYDLVQQHKSELKLYQSQVNYYGFSEKLSEQIQDFKKYSVTPEHLHTFLQDNDLKTRTRHKLEDISLIYQYFEERINGEFITSEDSLNHFIDILSQSEWIKRAEVYIDGFHNFSTLEYQIIKALVQSAKKVTVLLTTDGNEDPFSLFRKPSEVLTHLKEIAKDLNIELQQQFFKQQYRFNNKDLIQLEQQFDALQINPIAYDGSINILESSSIREEVNEVARQIIKDTRDKQYRYQDIAILYRDEAYAYLFDSVLPQYDIPFNIDTKRSMTHHPIMEMVRSLLEVIQTNWNISPMMRLIKTNILTNHFKDSAYLIDLLENFVVERGVYGKRWLDEKLFSIDNFTKMGRKEHKLTTEEREDFEQVVHLKNDIIDKILTFEKAMNEAENVRGFATAFYETMEAFDLPKYLMTHRDQLDVDGRHEEAEEIDQIWNGLIQILDDLVTVFDNEEMTLKRFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKKHIYMVGMNDGAMPQPVSSSSLITDEEKKVFEQQAQVELSPTSDILQMDEAFVCYIAMTRGSEQVTFSYSLMGAQGEDKEKSPFIDQIQGLFNGLEVMNIHYQHNAQPLSLMEHPHQTKVVLFESLKAWLEAEMVADVWVDAYQVMRDNDKLNNGLEYLLTALTYDNETVKLDEPLAASLYGSTINASVSRFEGYNDCPFKHYANHGLRLNERTKYKLENFDLGNIFHTALKYISDKVDGDFKNLDNKKIHALTVEALENVLPQVQFNLMDSNAYYRYVSKRIGVIVESTLKALRYQNKNTKFKPQRFEAGFRKTPNNSEELIAQPLITKQGIPVNIRGQIDRIDAYTKDDKSYINIIDYKSSNPSAKLDLKKVYYGKQMQMMTYMDIALQNAQRLGLSNEIKPGGLLYFHVHDERLSFKDWGELEDDALTQDKLEQAFLKEYKLRGLVNSDMDVVDALDIRLEEISKSDIVPVSLKKDGSIGSRGSSVADETTIHKFIKHNKDNFIKTATNIMEGHTEVAPLKFDDQLPCQFCNFQSVCHVDTIIDSKHYRHVDETIDPIKAIQDVELESGDHNE
>NZ_CUEW01000013.1|WP_011276252.1|9694_10267_+|signal-peptidase-I
MKKEIVEWIVAIAVGLLLVWVMVNFVAKSYTIKGDSMDPTLKDGEHVMVNILGYKVGDIKKGNVIVFHANQQDDYVKRVIGVPGDNVIYKNDKLYVNGKKINEPYLDYNEKRKQGEYITGSFETKDLLNANPKSNIIPKGKYLVLGDNREVSKDSRAFGLIDRDQIVGKVSFRFWPFSEFKFNFNPDNEK
>NZ_CUEW01000013.1|WP_053015823.1|9155_9680_+|signal-peptidase-I
MRRVTSWIVAFLFACLFVMFIQMFLVKSAVVQTDDMSPTLNKGDRVIINKIKVTFNMLKDGDIIMYRHNNQLHFGRLVGKPGESIEVINGKLYRDDRQVNKFYAKNRDINNFAIRDLHDSDGDIILPNSYFILNDNGDKQSDSRTYGLIDKDDIVGDVSLKYYPFKEFTYQFNK
>NZ_CUEW01000013.1|WP_016931167.1|8578_9151_+|TVP38/TMEM64-family-protein
MFHQIEQWFDLLQGFGYLAGFIILFFRAIVPVLPLTLYVILCVHAYGFIAGTIISWLGVVAGTYTVFFFCRKFVNANFMKRIKSRRSIERLIHFIDRQGLVPIFILMCFPFTPNTLVNFVASFSHIRGKYYFIILLISKLISITFLAIMGKSVTSFFTHPVRAIMVLIVTIALWFVGKKVEGYFMGSDKE
>NZ_CUEW01000013.1|WP_011276255.1|7017_8349_+|glucose-6-phosphate-isomerase
MTHIQLDYGKALEFFGQHEIDQQQDIVKTIHKTIHEGTGAGSDFLGWVNLPEDYDKKEFSRIVEASKRIKSNSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLSDKDFSVNVISKSGTTTEPAVAFRLFKQLVEDKYGKAEAKKRIFATTDKAKGALKQLADNEGYETFVVPDDVGGRYSVLTAVGLLPIATAGINIESIMIGANKARKELSSDKLDENIAYQYATIRNILYSKGYTTEMLINYEPSMQYFNEWWKQLYGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNNPKHDITIEEDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNVVVNIPRLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDKKKELEERL
>NZ_CUEW01000013.1|WP_033079774.1|5481_6684_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVKWLIDKGYDVVAVCLDVGEGKDLDVVYSKALDMGAVECHIIDATKEFSDDFVSYAIKGNLMYENSYPLVSALSRPLIAKKLVEIAEQTNSVGIAHGCTGKGNDQVRFEVAIKALNPNLKAFAPVREWGWSREEEIDYAIKHNIPVGINHDSPYSIDQNLWGRANECGILEDPYAAPPKDAYDLTAELEDTPDTPDEIILSFKNGVPVQLNHQDYDLDQLILTLNELAGKHGIGRIDHVENRLVGIKSREIYETPGAEVILKAHKALETLTLTKDVAHFKPVIEKQFAEQTYNGLWFSPLTDSLKLFIDSTQQYVEGDVRIKLFKGNAIVNGRKSLYTLYDEKLATYTKEDAFNQSAAVGFIDIYGLPTQVNAYLHGGYSNE
>NZ_CUEW01000013.1|WP_011276257.1|4106_5489_-|argininosuccinate-lyase
MSSKAWGGRFQQQPEDWVDEFNASIDFDQTLLDEDVQGSIAHATMLANQNIISQDDKDAIINGLKEIQQDFHNGKLAFKKSLEDIHLNIEHELIQRVGDAGGKLHTGRSRNDQVATDLHLYVKKEVLEIQDLIRSFQTSILKLAQSHVDTIMPGYTHLQRAQPISFAHHVMTYFWMLERDYSRFVDSMKRIDISPLGAAALSGTTHPIDRHETQQLLEFSSVYENSLDAVSDRDYIIETLHNISLTMIHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRATGHLMSMLVTLKGLPLAYNKDLQEDKEGLFDSVRTIKGSLRIFEGMLDTMTVNTDRLNETVHQDFSNATELADYLVAKDVPFRKAHEIVGKIVFECIQQGIYLLDVPLERYKELNSNIDQDVYDYLKPENCLSRRKSYGSTGQDAVRHQLKVAEKLLNND
>NZ_CUEW01000013.1|WP_011276258.1|2956_3919_-|glycerophosphodiester-phosphodiesterase
MKASNKGIISCLTVASLSLAIIHTPVEASGGESSNTTTTNLTNASKTQNNHTNWSRNLTGERHTTIAHRGASGYAPEHTFAAYDKSYNELGASYIEIDLQRTKDGHLVAMHDETVDRTTNGSGRVEDYTLAELKKLDAGSSFNEQNPQLAKDSYKGATVPTLDEILTRYGTDANYYIETKQPDVYPGMEQQLLDTLNRHNMLTSNSLENGHVLVQSFSEASLLKMHQLNSNVPLIRLLDKGELAQQSEADLQRIRSYAIGVGPEYSDLNAQNTAHLKDLGFLVHPFTVNETADMQRLNQYGVDGVFTNYADQYKAISSQK
>NZ_CUEW01000013.1|WP_011276247.1|19041_19443_+|YisL-family-protein
MLHMHIASWALTIILYVIAFLHISKSQGPTPMFKPLQMALRVFMLLTLFSGFWLLIQEFMAASHGGGGNHMLLTLKMLCGIAVVALMEVSIAKRKKHEASHGLFWATIILIIITMSLGIILPWGPISSLFGIS
>NZ_CUEW01000013.1|WP_037570611.1|19516_20839_-|CoA-disulfide-reductase
MRKIIVVGAVAGGATCASQIRRLDKDSEITIFEKDRDMSFANCGLPYFIGNIVNERKDVLPITPDVFKEKKDITVKTYHEVIAINDKDQTVTVVNRQTNEKFKASYDKLILSPGAGANSLGFDSDYIFTLRNMEDTDAIDQFIDQHQAKKALVVGAGYISLEVLENLYARGLDVTLIHRSEKVNKLMDQDMNQVIFDELDSRHIPYRLNEEIVSVKDHLVTFKSGIQEDFDIIIEGVGTHPNSKFIESSNVALDDKGFVKVNYKFETNIPNIYALGDVITSTYRHVNLPAQVPLAWGAHRGASVIAEQLAGNKNIIFKGFLGTNIVKFFDYTLASVGIKVEELTHFDYQMVELNSGTHAGYYPGNTNVHLRVYFDTNNRHLLRAAAVGKTGVDKRIDVLSMAMMSELTIDELTEFEVAYAPPYSHPKDLVNMIGYKARDL
>NZ_CUEW01000013.1|WP_016931172.1|20920_21745_-|Cof-type-HAD-IIB-family-hydrolase
MKPYLICLDLDGTLLNDNKEISDYTKQVLTTLKKQGHRIMIATGRPYRASQIYYHELNMDTPIVNFNGAYVHHPKSDDFKTTHEVLDVDLARNMIETLQKAKVTNIIAEVRDHVFINNHDPRLFEGFSMGNPKIETGNLLEELDEAPTSLLVEAEEIYIPRIKQMLTRFYAENIEHRRWGAPFPVIEIVKRGISKARGIDQVKDYLGIEPSHIIAFGDEDNDIEMIKYAKYGIAMDNGLDELKHIANHITYSNNDDGIGRYLNDFFKLNIPYKG
>NZ_CUEW01000013.1|WP_011276244.1|21945_22254_+|metal-sulfur-cluster-assembly-factor
MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDDGLCTVEMTLTSMGCPLGPQIIEQIKTVLAEIPEIQDTEVNIVWNPPWNKDMMSRYAKIALGVG
>NZ_CUEW01000013.1|WP_011276243.1|22700_24527_+|acetyltransferase
MKQDFEKGKQRKTKMRYMPGLDGLRAIAVLGIIIYHLNRKWLTGGFIGVDTFFVISGYLITSLLLKEYEERGIISLKQFWIRRVKRLLPAVVALLIVVGIATLIFEPQQIVRVKHDIIAALFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYLFFPFVLVILLLTIKKYRNVTLILWIISLVSLLAMVIISQPNVGYSRVYFGTDTRLQTLLLGVILAFVWPPFKLKANPPKVLQRSIDGIGILGLIILIYLFFTVKDTSAWIYNGGFYLISGMTLFIIASVVHPSSILAKVLGHRIFVYIGKRSYSLYLWHFPVISFIHIHFVDGQLPIYVYFVDIILTVLFAELSYRYIETPFRREGLKAFSFNYLKRPKFIRTIVSIIAVIPIVLLFLGVFDRFGKDEIDNKANSFNTNDQDKYLVRMMPGENIKIDGSSSNSKSKKQVYTNISPLLIGDSVMVDIGEEFKSQVPKATIDGKVGRHLQEALSIAGNYSNYNKPSDKVVLELGTNGDFTEEELNQLINKFGKAQIYLVNTRVPRDWQDNVNKQLANAAKKHKNVTLVDWYQRSAGHSEYFAPDGVHLENSGVKALSDEIIKTIKKNSKNK
>NZ_CUEW01000013.1|WP_053015824.1|24821_27431_+|ATP-dependent-chaperone-ClpB
MDINQMTYAIQGALQKAVELSKENELQNIEIEAILKGTLEETDSLFKSILERANIDTDELNQAYTNKLKNYPSVQGDNIQYGQYIGAKANELLNKAESYMKEYEDEYISMEHVLRAAMDIDDTTKQFVGNKEEVVKEIITKVRGGNHVTSQNPEVNYEALEKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPESLLDKTIFELDLSALVAGAKFRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVGVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKHRLEELQEELSNEKEKQASLQSRVEQEKEKIANVQEKRAELDRSRQALEDAQTEGNLEKAAELQYGTIPQLEKELKEFEEAYQDEQGDSERMIREVVSDEEIGDIVSQWTGIPVSKLVETEREKLLNLSDILHERVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHSVSRLIGAPPGYVGHDEGGQLTEAVRRNPYSVILLDEVEKAHSDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKDTGDITEETEKAVMDSLHAFFKPEILNRMDDIVLFKPLSINDMSMIVDKILTQLNIRLMDQRISIEVSDDAKKWLGEEAYEPQFGARPLKRFVQRQIETPLARMMIKEGMPEGTVVNVDLDDNHELTFDVQKPENE
>NZ_CUEW01000013.1|WP_011276241.1|27731_27926_-|YjzD-family-protein
MKYLVTFIWAVILLQMVNFVLNSLNGGGTLNFITPIVLAVIFTIVIAILAAMIKPDDFTRSGNR
>NZ_CUEW01000013.1|WP_016931174.1|28131_29073_+|ketoacyl-ACP-synthase-III
MNVGIKGFGAYAPEKVVDNAYFESFLETSDEWISKMTGIKERRWASEDQDTSDLAFEASKKAIEDAGITPADIDMIIVATATGDMPFPSVANILQEKLGTRKVPTMDQLAACSGFMYSMITAKQYVQSGDYKNILVVGADKLSKITDLTDRSTAVLFGDGAGAVVIGEVSEGRGIISYEMGSDGNGGKYLYLNKDTGKLVMNGREVFKFAVRIMGEASTRVVDKAGLQSDDIDMFIPHQANIRIMESARERLGIEREKMSVSVNRFGNTSAASIPLSISQELENGRIKDDDTLVLVGFGGGLTWGAMVIKWGK
>NZ_CUEW01000013.1|WP_016931175.1|29086_30331_+|beta-ketoacyl-ACP-synthase-II
MTENKRVVITGMGALSPIGNDAQTSWENALKGVNGIDTITRIDTEDYNVHLAGELKDFNVEDHIEKKEARRMDRFTQYAVVAARQAVEDAKLEINDETANRIGVWIGSGIGGMETFETAHTTLQNKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGSTVTACATGTNSIGEAFKIIQRGDADAMITGGTEAPITHMALAGFSASRALSTNDDKETACRPFQEGRDGFVMGEGAGILVIESLESAQARGAQIYAEIVGYGSTGDAYHITAPAPEGEGGSRAMQAALDDAGIEAKDVQYLNAHGTSTPVGDMYEIRAIKNTFGDAANQLKVSSTKSMTGHLLGATGGLEAIFSALSIRDSKVAPTIHANTPDPECDLDIVPNEAQDLEITYAMSNSLGFGGHNAVLVFKKFED
>NZ_CUEW01000013.1|WP_033079768.1|30403_30781_-|DUF3899-domain-containing-protein
MKNLKNWMIWLIITPILSMILWIIFTNHTFVSYINTLFYLSLIIFISIFFILLVQEGIFDATSYGFRRIRYQLSSRSKKRTMADDEFLNPQQVKKEHYFISTWIAPALICNIAYFVMTIIISFLL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CUEW01000013_1	1.1\|18865\|27\|NZ_CUEW01000013\|CRISPRCasFinder	18865-18891	27	MN693238	Marine virus AFVG_25M402, complete genome	24675-24701	6	0.778

1. spacer 1.1|18865|27|NZ_CUEW01000013|CRISPRCasFinder matches to MN693238 (Marine virus AFVG_25M402, complete genome) position: , mismatch: 6, identity: 0.778

cacaagcaaagcaggctggggttgggg	CRISPR spacer
cacaagcaacgcaggctgggattctta	Protospacer
********* **********.**   .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_CUEW01000034

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1452 : 9922

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011276166.1\|1452_1935_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	46.0
WP_029376687.1\|1921_3046_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_053038137.1\|3049_3754_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	2.1e-47	42.9
WP_011276163.1\|3753_4014_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_011276162.1\|4015_4687_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_011276161.1\|4679_6869_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.1e-137	39.4
WP_011276160.1\|6847_8332_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.7e-47	33.6
WP_011276159.1\|8324_9356_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.7e-69	45.5
WP_011276158.1\|9355_9922_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.7e-29	40.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_CUEW01000002

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

778 : 10753

Staphylococcus_phage(77.78%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053032531.1\|778_1609_+\|tail	phage tail family protein	U3PDX5	Staphylococcus_phage	1.0e-80	54.3
WP_053032529.1\|1620_3648_+	hypothetical protein	NA	NA	NA	NA
WP_053032527.1\|3696_5916_+	hypothetical protein	U3PDY0	Staphylococcus_phage	7.4e-155	44.9
WP_154391804.1\|6122_6515_+	hypothetical protein	A0A2H4JIB4	uncultured_Caudovirales_phage	1.6e-49	67.7
WP_053017989.1\|6498_6897_+	hypothetical protein	A0A2H4JAU6	uncultured_Caudovirales_phage	7.6e-34	56.1
WP_049426314.1\|6945_7245_+	hypothetical protein	A0A1W6JNR5	Staphylococcus_phage	1.5e-42	99.0
WP_080366938.1\|7241_8957_+	CHAP domain-containing protein	A0A1W6JQL2	Staphylococcus_phage	0.0e+00	89.6
WP_037557878.1\|9186_9402_+	hypothetical protein	A0A0D4DBZ6	Staphylococcus_phage	1.8e-34	100.0
WP_049394982.1\|9391_9847_+	DUF2335 domain-containing protein	A0A0D4DCC1	Staphylococcus_phage	2.9e-74	99.3
WP_154393739.1\|10420_10753_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-51	91.8

Anti-CRISPR protein detection

Acr_ID: NZ_CUEW01000002.1|WP_154393739.1|10420_10753_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CUEW01000002.1|WP_154393739.1|10420_10753_+|hypothetical-protein

10420_10753_+

110 aa aa

AcrIIA13b

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3642\|WP_053038109.1\|AcrIIA13b\|II-A\|Verified\|Staphylococcus-haemolyticus	0.990909090909091	1	0.8527131782945736

778-10753

10. NZ_CUEW01000017

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2696 : 12824

Tupanvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011275583.1\|2696_4970_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.9e-66	30.2
WP_011275584.1\|4991_5510_+	adenine phosphoribosyltransferase	A0A2K9L2N8	Tupanvirus	9.6e-13	31.8
WP_011275585.1\|5878_8068_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I7SAJ7	Vibrio_phage	8.8e-07	31.9
WP_011275586.1\|8083_8536_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_046309219.1\|8532_9408_+	SH3 domain-containing protein	A0A067ZJB6	Vibrio_phage	1.2e-15	31.5
WP_053038118.1\|9768_11040_+\|tRNA	histidine--tRNA ligase	A0A2K9L6G5	Tupanvirus	4.0e-12	21.9
WP_011275589.1\|11057_12824_+\|tRNA	aspartate--tRNA ligase	A0A1V0SIS0	Klosneuvirus	9.2e-23	24.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

11. NZ_CUEW01000026

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

9233 : 23107

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033079624.1\|9233_10289_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	2.8e-19	26.7
WP_011276430.1\|10463_10997_+	5'-3'-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	8.0e-31	39.0
WP_049426014.1\|11069_11996_-	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_011276428.1\|12613_14119_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.9e-61	32.7
WP_011276427.1\|14419_14920_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.7e-51	70.8
WP_087503729.1\|14925_15825_-	DMT family transporter	NA	NA	NA	NA
WP_011276425.1\|16598_16997_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.9e-53	75.8
WP_011276424.1\|16959_19065_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	94.0
WP_011276423.1\|19192_20161_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	1.4e-177	94.7
WP_011276422.1\|20410_21379_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.7e-151	88.5
WP_011276421.1\|21368_22328_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	5.7e-11	72.0
WP_011276420.1\|22324_23107_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.3e-16	27.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

12. NZ_CUEW01000051

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 15222

Staphylococcus_phage(100.0%)

terminase,tail,capsid,portal,head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080366939.1\|0_4904_-	hypothetical protein	A0A0D4DC81	Staphylococcus_phage	4.1e-12	83.0
WP_053032481.1\|5108_5642_-	hypothetical protein	A0A1W6JPW8	Staphylococcus_phage	4.2e-72	83.0
WP_053032479.1\|5713_6304_-	hypothetical protein	A0A0D4DCZ2	Staphylococcus_phage	5.1e-103	93.4
WP_053032477.1\|6310_6706_-	hypothetical protein	A0A0D4DCP8	Staphylococcus_phage	1.1e-66	95.4
WP_053032475.1\|6698_7124_-	hypothetical protein	A0A0D4DCC4	Staphylococcus_phage	5.7e-72	97.2
WP_053032473.1\|7123_7447_-\|head	phage head closure protein	A0A0D4DC77	Staphylococcus_phage	7.7e-53	98.1
WP_053032471.1\|7416_7740_-\|head,tail	phage gp6-like head-tail connector protein	A0A0D4DBY0	Staphylococcus_phage	2.5e-51	97.2
WP_053020666.1\|7939_9241_-\|capsid	phage major capsid protein	A0A0D4DCP3	Staphylococcus_phage	7.9e-189	90.1
WP_049394970.1\|9290_9860_-\|head,protease	HK97 family phage prohead protease	A0A0D4DCC0	Staphylococcus_phage	1.6e-101	99.5
WP_053020696.1\|9831_11010_-\|portal	phage portal protein	A0A0D4DC70	Staphylococcus_phage	2.3e-219	98.5
WP_154391803.1\|11078_11255_-	hypothetical protein	A0A0D4DBX4	Staphylococcus_phage	7.7e-23	98.3
WP_053032470.1\|11268_13020_-\|terminase	terminase large subunit	A0A0D4DCY2	Staphylococcus_phage	0.0e+00	96.9
WP_053032469.1\|13012_13483_-\|terminase	phage terminase small subunit P27 family	A0A0D4DCN9	Staphylococcus_phage	1.8e-82	96.8
WP_053032468.1\|13609_13957_-	HNH endonuclease	A0A0D4DD69	Staphylococcus_phage	4.8e-61	98.3
WP_049394966.1\|14144_14591_-	transcriptional regulator	A0A0D4DCX6	Staphylococcus_phage	1.7e-79	100.0
WP_037557836.1\|14604_14793_-	DUF1514 domain-containing protein	A0A0D4DCK3	Staphylococcus_phage	1.8e-22	96.8
WP_053031891.1\|14792_14951_-	transcriptional regulator	A0A0D4DCF9	Staphylococcus_phage	2.7e-19	92.3
WP_053017332.1\|14943_15222_-	hypothetical protein	H9A0M2	Staphylococcus_phage	4.3e-44	97.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage