CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_JNGP01000027	Listeria monocytogenes strain 2012-L5322 contig_27, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000051	Listeria monocytogenes strain 2012-L5322 contig_57, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000004	Listeria monocytogenes strain 2012-L5322 contig_4, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000020	Listeria monocytogenes strain 2012-L5322 contig_20, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000025	Listeria monocytogenes strain 2012-L5322 contig_25, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000059	Listeria monocytogenes strain 2012-L5322 contig_67, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000017	Listeria monocytogenes strain 2012-L5322 contig_17, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000062	Listeria monocytogenes strain 2012-L5322 contig_76, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000049	Listeria monocytogenes strain 2012-L5322 contig_55, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000063	Listeria monocytogenes strain 2012-L5322 contig_78, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000010	Listeria monocytogenes strain 2012-L5322 contig_10, whole genome shotgun sequence	0 crisprs	csa3	0	0	2	0
NZ_JNGP01000021	Listeria monocytogenes strain 2012-L5322 contig_21, whole genome shotgun sequence	0 crisprs	casR,WYL	0	0	0	0
NZ_JNGP01000006	Listeria monocytogenes strain 2012-L5322 contig_6, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000052	Listeria monocytogenes strain 2012-L5322 contig_58, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000047	Listeria monocytogenes strain 2012-L5322 contig_53, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000050	Listeria monocytogenes strain 2012-L5322 contig_56, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000019	Listeria monocytogenes strain 2012-L5322 contig_19, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000067	Listeria monocytogenes strain 2012-L5322 contig_84, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000033	Listeria monocytogenes strain 2012-L5322 contig_33, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000028	Listeria monocytogenes strain 2012-L5322 contig_28, whole genome shotgun sequence	0 crisprs	RT	0	0	0	0
NZ_JNGP01000057	Listeria monocytogenes strain 2012-L5322 contig_65, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000003	Listeria monocytogenes strain 2012-L5322 contig_3, whole genome shotgun sequence	0 crisprs	DinG	0	0	0	0
NZ_JNGP01000058	Listeria monocytogenes strain 2012-L5322 contig_66, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000061	Listeria monocytogenes strain 2012-L5322 contig_73, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000041	Listeria monocytogenes strain 2012-L5322 contig_43, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000037	Listeria monocytogenes strain 2012-L5322 contig_38, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000068	Listeria monocytogenes strain 2012-L5322 contig_93, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000018	Listeria monocytogenes strain 2012-L5322 contig_18, whole genome shotgun sequence	0 crisprs	WYL	0	0	0	0
NZ_JNGP01000002	Listeria monocytogenes strain 2012-L5322 contig_2, whole genome shotgun sequence	0 crisprs	cas3,DEDDh	0	0	2	0
NZ_JNGP01000023	Listeria monocytogenes strain 2012-L5322 contig_23, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000045	Listeria monocytogenes strain 2012-L5322 contig_50, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000034	Listeria monocytogenes strain 2012-L5322 contig_34, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000035	Listeria monocytogenes strain 2012-L5322 contig_35, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000066	Listeria monocytogenes strain 2012-L5322 contig_83, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000064	Listeria monocytogenes strain 2012-L5322 contig_79, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000007	Listeria monocytogenes strain 2012-L5322 contig_7, whole genome shotgun sequence	1 crisprs	NA	1	4	1	1
NZ_JNGP01000040	Listeria monocytogenes strain 2012-L5322 contig_42, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000044	Listeria monocytogenes strain 2012-L5322 contig_49, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000014	Listeria monocytogenes strain 2012-L5322 contig_14, whole genome shotgun sequence	0 crisprs	NA	0	0	0	1
NZ_JNGP01000016	Listeria monocytogenes strain 2012-L5322 contig_16, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000026	Listeria monocytogenes strain 2012-L5322 contig_26, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000055	Listeria monocytogenes strain 2012-L5322 contig_62, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000008	Listeria monocytogenes strain 2012-L5322 contig_8, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JNGP01000029	Listeria monocytogenes strain 2012-L5322 contig_29, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000005	Listeria monocytogenes strain 2012-L5322 contig_5, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000065	Listeria monocytogenes strain 2012-L5322 contig_82, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000056	Listeria monocytogenes strain 2012-L5322 contig_64, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000032	Listeria monocytogenes strain 2012-L5322 contig_32, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000042	Listeria monocytogenes strain 2012-L5322 contig_44, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JNGP01000039	Listeria monocytogenes strain 2012-L5322 contig_41, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000022	Listeria monocytogenes strain 2012-L5322 contig_22, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JNGP01000038	Listeria monocytogenes strain 2012-L5322 contig_40, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000009	Listeria monocytogenes strain 2012-L5322 contig_9, whole genome shotgun sequence	0 crisprs	cas3	0	0	0	0
NZ_JNGP01000053	Listeria monocytogenes strain 2012-L5322 contig_59, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000031	Listeria monocytogenes strain 2012-L5322 contig_31, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000043	Listeria monocytogenes strain 2012-L5322 contig_46, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000060	Listeria monocytogenes strain 2012-L5322 contig_70, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000036	Listeria monocytogenes strain 2012-L5322 contig_36, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000030	Listeria monocytogenes strain 2012-L5322 contig_30, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000012	Listeria monocytogenes strain 2012-L5322 contig_12, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000011	Listeria monocytogenes strain 2012-L5322 contig_11, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JNGP01000046	Listeria monocytogenes strain 2012-L5322 contig_51, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000024	Listeria monocytogenes strain 2012-L5322 contig_24, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_JNGP01000013	Listeria monocytogenes strain 2012-L5322 contig_13, whole genome shotgun sequence	1 crisprs	cas3	0	0	0	0
NZ_JNGP01000054	Listeria monocytogenes strain 2012-L5322 contig_61, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000015	Listeria monocytogenes strain 2012-L5322 contig_15, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_JNGP01000001	Listeria monocytogenes strain 2012-L5322 contig_1, whole genome shotgun sequence	0 crisprs	csa3	0	0	2	0
NZ_JNGP01000048	Listeria monocytogenes strain 2012-L5322 contig_54, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 22182

Listeria_phage(100.0%)

portal,capsid,terminase,plate,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060586176.1\|0_376_+	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	1.7e-56	89.5
WP_060579693.1\|379_766_+	DUF2481 family protein	A0A0B5CU14	Listeria_phage	3.3e-42	66.1
WP_003734968.1\|936_1371_+	hypothetical protein	A8AU03	Listeria_phage	5.3e-73	95.1
WP_003734122.1\|1736_2276_+	hypothetical protein	NA	NA	NA	NA
WP_046336528.1\|2321_3116_+\|terminase	terminase small subunit	A8ASJ1	Listeria_phage	1.6e-11	70.4
WP_010989956.1\|3084_4416_+\|terminase	PBSX family phage terminase large subunit	Q9T1C1	Listeria_phage	1.1e-259	98.0
WP_009925050.1\|4428_6198_+\|portal	phage portal protein	A8ASJ3	Listeria_phage	5.0e-263	91.0
WP_039381673.1\|6198_7338_+\|capsid	phage minor capsid protein	A8ASJ4	Listeria_phage	1.3e-200	96.0
WP_009925047.1\|7416_7986_+	phage scaffolding protein	A0A0B5CTV7	Listeria_phage	1.2e-80	97.9
WP_031645714.1\|8009_8909_+\|capsid	phage major capsid protein	Q9T1B7	Listeria_phage	1.0e-166	99.7
WP_009925045.1\|8908_9067_+	hypothetical protein	A8ASJ7	Listeria_phage	9.6e-17	92.3
WP_009925044.1\|9068_9464_+	hypothetical protein	A0A059T5E3	Listeria_phage	2.2e-54	82.4
WP_039381670.1\|9463_9826_+	hypothetical protein	A0A059T658	Listeria_phage	3.3e-60	94.2
WP_029508830.1\|9825_10164_+\|capsid	minor capsid protein	A0A0B5CTV8	Listeria_phage	5.4e-57	95.5
WP_010679811.1\|10163_10571_+	hypothetical protein	A0A0B5CU21	Listeria_phage	1.2e-66	98.5
WP_031644589.1\|10573_11011_+	hypothetical protein	A0A0B5CYN3	Listeria_phage	1.2e-77	99.3
WP_031644591.1\|10940_11273_+	Ig-like domain-containing protein	Q9T1B0	Listeria_phage	4.1e-49	98.2
WP_031644594.1\|11327_11750_+\|tail	phage tail assembly chaperone	Q9T1A9	Listeria_phage	2.0e-69	99.3
WP_031644596.1\|11755_12355_+	bacteriophage Gp15 family protein	A0A0B5CTW0	Listeria_phage	8.1e-72	68.0
WP_039381664.1\|12370_17734_+	tape measure protein	A0A059T7P2	Listeria_phage	0.0e+00	88.1
WP_031644600.1\|17735_18554_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	3.6e-147	92.3
WP_003722528.1\|18562_19588_+\|tail	phage tail protein	Q9T1A5	Listeria_phage	4.3e-198	98.2
WP_003722527.1\|19588_20617_+	hypothetical protein	Q9T1A4	Listeria_phage	4.6e-192	100.0
WP_039381660.1\|20616_21690_+\|plate	BppU family phage baseplate upper protein	Q9T1A3	Listeria_phage	1.1e-175	88.0
WP_003722525.1\|21701_22019_+	hypothetical protein	Q9T1A2	Listeria_phage	6.2e-55	100.0
WP_003722524.1\|22023_22182_+	hypothetical protein	Q9T1A1	Listeria_phage	6.0e-19	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_JNGP01000013

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_JNGP01000013_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JNGP01000013_1

37110-37261

Unclear

Consensus_repeat	Method
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_JNGP01000013_1

>merge|NZ_JNGP01000013|1|37110-37261|CRISPRCasFinder
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTCATTCGAATTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACGCCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTC

>NZ_JNGP01000013|1|1|37110-37261|CRISPRCasFinder
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCAGAACCGAGCTC	ATTCGAATTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACG
CCAATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JNGP01000013.1\|WP_003733151.1\|43921_44482_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_JNGP01000013.1\|WP_003722728.1\|29437_30394_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_JNGP01000013.1\|WP_009930499.1\|40531_41206_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_JNGP01000013.1\|WP_003722731.1\|32615_34205_+\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_JNGP01000013.1\|WP_003722740.1\|42517_43141_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_JNGP01000013.1\|WP_003722727.1\|28013_29387_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_JNGP01000013.1\|WP_003722739.1\|41282_42224_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_JNGP01000013.1\|WP_003722725.1\|26890_27199_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_JNGP01000013.1\|WP_003733150.1\|43230_43815_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_JNGP01000013.1\|WP_003722732.1\|34535_36068_+\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_JNGP01000013.1\|WP_003722723.1\|24308_25001_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_JNGP01000013.1\|WP_003722726.1\|27318_27627_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_JNGP01000013.1\|WP_003722735.1\|39162_39486_+\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NZ_JNGP01000013.1\|WP_003722736.1\|39620_40082_+\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_JNGP01000013.1\|WP_003733152.1\|44596_48136_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_JNGP01000013.1\|WP_003722729.1\|30436_31150_-\|listeriolysin-O-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NZ_JNGP01000013.1\|WP_003733146.1\|38221_39091_+\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_JNGP01000013.1\|WP_003725735.1\|40132_40465_-\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_JNGP01000013.1\|WP_003733144.1\|31420_32374_-\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_JNGP01000013.1\|WP_003722724.1\|24997_26206_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528

Protein	Function_ID	Function_description	E-value
NZ_JNGP01000013.1\|WP_003733151.1\|43921_44482_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.69718e-108
NZ_JNGP01000013.1\|WP_003722728.1\|29437_30394_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_JNGP01000013.1\|WP_009930499.1\|40531_41206_-\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.81561e-21
NZ_JNGP01000013.1\|WP_003722731.1\|32615_34205_+\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	1.50399e-178
NZ_JNGP01000013.1\|WP_003722740.1\|42517_43141_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_JNGP01000013.1\|WP_003722727.1\|28013_29387_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_JNGP01000013.1\|WP_003722739.1\|41282_42224_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_JNGP01000013.1\|WP_003722725.1\|26890_27199_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_JNGP01000013.1\|WP_003733150.1\|43230_43815_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.15404e-10
NZ_JNGP01000013.1\|WP_003722732.1\|34535_36068_+\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.90486e-139
NZ_JNGP01000013.1\|WP_003722723.1\|24308_25001_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_JNGP01000013.1\|WP_003722726.1\|27318_27627_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_JNGP01000013.1\|WP_003722735.1\|39162_39486_+\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	5.76244e-49
NZ_JNGP01000013.1\|WP_003722736.1\|39620_40082_+\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	5.22035e-59
NZ_JNGP01000013.1\|WP_003733152.1\|44596_48136_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_JNGP01000013.1\|WP_003722729.1\|30436_31150_-\|listeriolysin-O-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NZ_JNGP01000013.1\|WP_003733146.1\|38221_39091_+\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	1.12447e-86
NZ_JNGP01000013.1\|WP_003725735.1\|40132_40465_-\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_JNGP01000013.1\|WP_003733144.1\|31420_32374_-\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	8.10719e-115
NZ_JNGP01000013.1\|WP_003722724.1\|24997_26206_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	4.34799e-62

>NZ_JNGP01000013.1|WP_003722732.1|34535_36068_+|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFTMTVKADSVGEEKLQNNTQAKKTPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSGGYLTDNDEIKVHVTPDNKITFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYVGNPVKEKEIILNSRTKRLVYNIKLIFAEPEVASWIVQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLKHNTDTSFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYEYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGQEILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGSRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHYNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKSQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_JNGP01000013.1|WP_003722731.1|32615_34205_+|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
>NZ_JNGP01000013.1|WP_003733144.1|31420_32374_-|phosphatidylinositol-specific-phospholipase-C
MYKNYLQRTLVLLLCFILYFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_JNGP01000013.1|WP_003722729.1|30436_31150_-|listeriolysin-O-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_JNGP01000013.1|WP_003722728.1|29437_30394_+|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_JNGP01000013.1|WP_003722727.1|28013_29387_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQDEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASKLMQRRINENHMRNGVTLVNPESTYIDIDVKIGQDTVIEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPEDALGIARAKQDNKLGYAKHLNHGK
>NZ_JNGP01000013.1|WP_003722726.1|27318_27627_+|septation-regulator-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_JNGP01000013.1|WP_003722725.1|26890_27199_+|septation-regulator-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_JNGP01000013.1|WP_003722724.1|24997_26206_+|ABC-transporter-permease
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKSSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGVIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_JNGP01000013.1|WP_003722723.1|24308_25001_+|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
>NZ_JNGP01000013.1|WP_003733146.1|38221_39091_+|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPITIKANACCDEYLQTPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVAKRFCSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_JNGP01000013.1|WP_003722735.1|39162_39486_+|DUF5502-family-protein
MYIKGRLIFFFVMFVIALCSVLILLIIKISVWKDEPFHLSDAKEIECLGSCEIKNTNQKIHFFSIKENLFEEKGDIAGILNEDEQKVADKSIFIVILDDEKGIANEE
>NZ_JNGP01000013.1|WP_003722736.1|39620_40082_+|YehR-family-lipoprotein
MKMLKKGTAVLFVMIMAVMLVACGDKEETKTYTLSQNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_JNGP01000013.1|WP_003725735.1|40132_40465_-|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_JNGP01000013.1|WP_009930499.1|40531_41206_-|DNA-alkylation-repair-protein
MITFDQLDTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVKLIESNNSDLIYLGLLAINPNKITTEQIEKWNIAFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAETLLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_JNGP01000013.1|WP_003722739.1|41282_42224_-|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_JNGP01000013.1|WP_003722740.1|42517_43141_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_JNGP01000013.1|WP_003733150.1|43230_43815_+|GNAT-family-N-acetyltransferase
MLDKSVPHISVIMVNHDATNYPEFHLPAGYSFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLTKRCIFVKAPNGEIIGTAMLWDGNTFGKMESRIHWVAVLDSHGGKGIAKALLSKILGLNKSKFVYLTTQTGSYQAIYLYRKFGFEKYVGKTPENWKTVNFQEEKETAWQIIENKIAEHQA
>NZ_JNGP01000013.1|WP_003733151.1|43921_44482_+|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNISIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_JNGP01000013.1|WP_003733152.1|44596_48136_+|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMTHTLNELKENEDKQALVENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYLPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEGNHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKEKASTEN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_JNGP01000014

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NZ_JNGP01000014.1|WP_003731276.1|38104_38356_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_JNGP01000014.1|WP_003731276.1|38104_38356_+|hypothetical-protein

38104_38356_+

83 aa aa

AcrIIA12

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3641\|WP_003731276.1\|AcrIIA12\|II-A\|Verified\|Listeria-monocytogenes	1.0	1	1.0

4. NZ_JNGP01000042

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

63 : 2434

Listeria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060579686.1\|63_546_-	single-stranded DNA-binding protein	A8ASP5	Listeria_phage	1.5e-73	86.9
WP_060579688.1\|546_801_-	hypothetical protein	A0A059T5G2	Listeria_phage	8.5e-39	90.4
WP_046421606.1\|800_1007_-	hypothetical protein	NA	NA	NA	NA
WP_003731705.1\|1003_1276_-	hypothetical protein	A8ATE2	Listeria_phage	2.0e-46	100.0
WP_003731704.1\|1272_1602_-	hypothetical protein	A8ATE1	Listeria_phage	1.1e-57	100.0
WP_014601509.1\|1602_1812_-	hypothetical protein	A8ATE0	Listeria_phage	1.7e-32	100.0
WP_014601510.1\|1808_2210_-	hypothetical protein	A8ATD9	Listeria_phage	2.6e-74	100.0
WP_014929526.1\|2287_2434_-	hypothetical protein	A8ATZ0	Listeria_phage	1.7e-20	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_JNGP01000008

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

79066 : 87352

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003733243.1\|79066_79633_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.9
WP_003733242.1\|79629_80679_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.6e-62	43.5
WP_003722245.1\|80697_82125_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_003733241.1\|82109_84329_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.5e-160	41.4
WP_003733240.1\|84321_85005_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|85008_85254_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003733239.1\|85265_85979_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.7e-42	38.7
WP_020246648.1\|86059_87352_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_JNGP01000022

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6070

Listeria_phage(88.89%)

integrase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_188186121.1\|0_348_-	YqaJ viral recombinase family protein	A0A0B5D133	Listeria_phage	5.4e-60	98.3
WP_031643418.1\|580_769_-	hypothetical protein	A0A059T7X9	Listeria_phage	3.8e-28	98.4
WP_020830690.1\|871_1078_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_060579667.1\|1067_1598_-	hypothetical protein	A8ATY1	Listeria_phage	1.5e-77	87.3
WP_060579668.1\|1719_2499_-	phage antirepressor KilAC domain-containing protein	A0A0B5CTU1	Listeria_phage	8.4e-138	95.7
WP_173346366.1\|2511_2688_-	hypothetical protein	A8ASM5	Listeria_phage	8.8e-19	56.4
WP_039381690.1\|2684_2921_-	hypothetical protein	A0A059T5E9	Listeria_phage	2.8e-36	97.4
WP_060579670.1\|2955_3177_-	helix-turn-helix transcriptional regulator	A8ASM3	Listeria_phage	2.5e-31	95.9
WP_060579672.1\|3339_3816_+	XRE family transcriptional regulator	A8ASM2	Listeria_phage	4.0e-58	82.4
WP_031290773.1\|3972_4140_+	hypothetical protein	NA	NA	NA	NA
WP_003731435.1\|4194_4845_+	hypothetical protein	NA	NA	NA	NA
WP_060579674.1\|4906_6070_+\|integrase	site-specific integrase	S5MNZ2	Brevibacillus_phage	2.4e-51	31.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_JNGP01000024

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 20252

Listeria_phage(100.0%)

tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060586184.1\|0_376_+	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	8.6e-56	87.9
WP_009924217.1\|379_763_+	DUF2481 family protein	A0A0B5CYS3	Listeria_phage	2.0e-63	97.6
WP_003727776.1\|891_1056_+	hypothetical protein	A8ASQ0	Listeria_phage	2.5e-20	92.6
WP_033918287.1\|1074_1509_+	hypothetical protein	A8AU03	Listeria_phage	1.5e-75	99.3
WP_015987428.1\|1690_2323_+	hypothetical protein	A8AU05	Listeria_phage	1.1e-114	100.0
WP_012951944.1\|2403_2631_+	hypothetical protein	A8AU06	Listeria_phage	1.5e-34	100.0
WP_015987406.1\|2670_3411_+	hypothetical protein	A8ATU5	Listeria_phage	3.7e-135	100.0
WP_047933366.1\|3376_4723_+\|terminase	PBSX family phage terminase large subunit	A8ATU6	Listeria_phage	5.9e-264	99.5
WP_015987416.1\|4737_6294_+	hypothetical protein	A8ATU7	Listeria_phage	4.8e-302	100.0
WP_015987421.1\|6298_7339_+	hypothetical protein	A8ATU8	Listeria_phage	1.6e-200	100.0
WP_015987425.1\|7434_7989_+	hypothetical protein	A8ATU9	Listeria_phage	2.3e-89	100.0
WP_015987427.1\|8011_8884_+	F420-dependent oxidoreductase	A8ATV0	Listeria_phage	1.2e-161	100.0
WP_172425835.1\|8897_9065_+	hypothetical protein	A8ATV1	Listeria_phage	1.7e-11	100.0
WP_012951937.1\|9065_9419_+	hypothetical protein	A8ATV2	Listeria_phage	7.6e-62	100.0
WP_015987430.1\|9418_9784_+	hypothetical protein	A8ATV3	Listeria_phage	4.4e-65	100.0
WP_015987407.1\|9773_10091_+	HK97 gp10 family phage protein	A8ATV4	Listeria_phage	9.9e-53	100.0
WP_003725064.1\|10087_10459_+	hypothetical protein	A8ATV5	Listeria_phage	8.5e-64	100.0
WP_060579645.1\|10463_11150_+	Ig domain-containing protein	A8ATV6	Listeria_phage	4.7e-116	99.6
WP_015987409.1\|11205_11637_+	hypothetical protein	A8ATV7	Listeria_phage	9.6e-75	100.0
WP_072225507.1\|11633_11945_+	hypothetical protein	A8ATV8	Listeria_phage	1.2e-42	98.9
WP_060579643.1\|11949_16749_+\|tail	phage tail tape measure protein	A8ATV9	Listeria_phage	0.0e+00	99.9
WP_015987412.1\|16745_18314_+\|tail	phage tail family protein	A8ATW0	Listeria_phage	7.3e-306	100.0
WP_060586187.1\|18326_20252_+\|tail	phage tail protein	A8ATW1	Listeria_phage	0.0e+00	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_JNGP01000002

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

217464 : 224887

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721506.1\|217464_217848_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003732709.1\|217869_218853_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
WP_020246559.1\|218867_219881_+	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_003721509.1\|220089_221580_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_003727000.1\|221591_222416_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.6
WP_003732711.1\|222428_222737_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003732712.1\|222797_223202_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_020246560.1\|223330_224887_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.3e-17	28.1

DBSCAN-SWA_2

355685 : 415194

Bacillus_virus(15.79%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003723562.1\|355685_356825_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|356905_357301_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|357451_357667_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003732794.1\|357785_358319_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003732795.1\|358336_359002_+	hypothetical protein	NA	NA	NA	NA
WP_003732796.1\|359263_360202_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|360316_361600_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|361785_363045_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723887.1\|363163_363730_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_009924619.1\|363764_364334_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723889.1\|364435_364978_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723890.1\|364987_365851_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723891.1\|365847_366633_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_060579637.1\|366766_367627_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	9.9e-39	43.2
WP_003732799.1\|367897_369976_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.2e-107	37.5
WP_003723999.1\|370038_371343_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003724000.1\|371625_372528_+	tyrosine recombinase XerC	A0A1B1IQT7	uncultured_Mediterranean_phage	8.0e-23	28.0
WP_003724001.1\|372548_373088_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003732800.1\|373101_374511_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IBU3	Erwinia_phage	6.8e-29	25.6
WP_003726695.1\|374531_375311_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003724129.1\|375413_375833_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003724130.1\|375854_376166_+	hypothetical protein	NA	NA	NA	NA
WP_003724131.1\|376168_377041_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724132.1\|377082_377679_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003732802.1\|377836_378244_+	CoA-binding protein	NA	NA	NA	NA
WP_003723731.1\|378424_380392_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	6.7e-123	42.5
WP_003723732.1\|380388_382848_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.6
WP_003723733.1\|382930_383398_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_031667889.1\|383727_385521_+	lmo1289 family class 1 internalin	NA	NA	NA	NA
WP_003723735.1\|385852_387655_+	class 1 internalin InlK	NA	NA	NA	NA
WP_003723736.1\|387688_389557_-	peptidoglycan O-acetyltransferase OatA	B5WZU0	Pseudomonas_phage	6.5e-43	31.9
WP_003723737.1\|389769_390468_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	1.3e-12	32.4
WP_003723738.1\|390700_392377_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_003732806.1\|392502_393420_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003719566.1\|393542_393776_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_072219379.1\|393886_395110_+	GTPase HflX	NA	NA	NA	NA
WP_003723434.1\|395102_396329_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_003719570.1\|396532_396901_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003723435.1\|396971_398306_+	type I glutamate--ammonia ligase	M1NM71	Moumouvirus	4.2e-12	23.8
WP_003723436.1\|398449_399745_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	1.8e-145	61.6
WP_003723437.1\|399788_400310_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003723438.1\|400340_400955_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003723439.1\|401111_401441_+	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723440.1\|401532_401760_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003732809.1\|401906_403901_+	transketolase	NA	NA	NA	NA
WP_003723442.1\|404121_404361_+	YneF family protein	NA	NA	NA	NA
WP_003732810.1\|404411_405254_-	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_003723444.1\|405272_406004_-	methyltransferase domain-containing protein	A0A1X9I6N4	Streptococcus_phage	1.2e-80	59.1
WP_003723445.1\|406025_406532_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	4.0e-56	66.7
WP_003723446.1\|406541_407846_-	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	9.5e-134	52.1
WP_010989732.1\|407835_409041_-	helicase SNF2	L0P6E9	Lactobacillus_phage	4.9e-92	47.1
WP_003723448.1\|409018_409393_-	hypothetical protein	NA	NA	NA	NA
WP_003723449.1\|409685_410414_+	UMP kinase	NA	NA	NA	NA
WP_003723450.1\|410413_410971_+	ribosome recycling factor	NA	NA	NA	NA
WP_003732812.1\|411200_411959_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003732813.1\|411972_412761_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003723453.1\|412775_413918_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003723454.1\|413931_415194_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_JNGP01000007

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_JNGP01000007_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_JNGP01000007_1

30241-30527

Orphan

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	CRT
TTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_JNGP01000007_1

>merge|NZ_JNGP01000007|1|30241-30527|PILER-CR,CRT,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATTTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAGTTTTAGTTACTTATTGTGAAATGTAAATTTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAGTTTTAGTTACTTATTGTGAAATGTAAATCTAAAACATCCTTCACTGTATCAACTCCTTTCTATATTTTAGTTACTTATTGTGAAATGTAAATACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTGTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_JNGP01000007|1|1|30241-30527|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_JNGP01000007|1|1|30241-30527|CRT
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCT
GTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_JNGP01000007|1|1|30242-30527|CRISPRCasFinder
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTATA
TTTTAGTTACTTATTGTGAAATGTAAAT	ACAATAATAGGATATTTTGGATTTGTCTGCGTTCCTG
TTTTAGTTACTTATTATGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_JNGP01000007.1\|WP_009930754.1\|30918_31497_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JNGP01000007.1\|WP_031644454.1\|39091_40507_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_JNGP01000007.1\|WP_003721291.1\|25640_26291_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_JNGP01000007.1\|WP_003733193.1\|22053_24114_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_JNGP01000007.1\|WP_003721298.1\|32308_32668_-\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NZ_JNGP01000007.1\|WP_003721301.1\|35450_35882_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_JNGP01000007.1\|WP_003733188.1\|31603_32284_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NZ_JNGP01000007.1\|WP_003733187.1\|32674_33133_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_JNGP01000007.1\|WP_003721295.1\|29068_30004_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_JNGP01000007.1\|WP_003721292.1\|26287_27334_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NZ_JNGP01000007.1\|WP_003733185.1\|35928_37359_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_JNGP01000007.1\|WP_003721289.1\|24747_25215_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_JNGP01000007.1\|WP_003721293.1\|27349_27643_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NZ_JNGP01000007.1\|WP_031668100.1\|33514_35350_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_JNGP01000007.1\|WP_003721311.1\|38575_38944_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NZ_JNGP01000007.1\|WP_003733192.1\|24117_24720_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NZ_JNGP01000007.1\|WP_003733194.1\|21294_21945_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NZ_JNGP01000007.1\|WP_003721290.1\|25231_25630_+\|hypothetical-protein	unknown	unknown	unknown
NZ_JNGP01000007.1\|WP_003721294.1\|27657_28929_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_JNGP01000007.1\|WP_003721303.1\|37479_38295_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483

Protein	Function_ID	Function_description	E-value
NZ_JNGP01000007.1\|WP_003721291.1\|25640_26291_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.74405e-108
NZ_JNGP01000007.1\|WP_031644454.1\|39091_40507_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.42897e-80
NZ_JNGP01000007.1\|WP_003721298.1\|32308_32668_-\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
NZ_JNGP01000007.1\|WP_003733193.1\|22053_24114_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.95572e-80
NZ_JNGP01000007.1\|WP_003721301.1\|35450_35882_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NZ_JNGP01000007.1\|WP_003733188.1\|31603_32284_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	6.36121e-61
NZ_JNGP01000007.1\|WP_003733187.1\|32674_33133_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.03599e-12
NZ_JNGP01000007.1\|WP_003721295.1\|29068_30004_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
NZ_JNGP01000007.1\|WP_003721292.1\|26287_27334_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NZ_JNGP01000007.1\|WP_003733185.1\|35928_37359_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.97856e-100
NZ_JNGP01000007.1\|WP_003721289.1\|24747_25215_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	3.45565e-37
NZ_JNGP01000007.1\|WP_003721293.1\|27349_27643_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
NZ_JNGP01000007.1\|WP_031668100.1\|33514_35350_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	8.29186e-120
NZ_JNGP01000007.1\|WP_003721311.1\|38575_38944_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	1.10012e-41
NZ_JNGP01000007.1\|WP_003733192.1\|24117_24720_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
NZ_JNGP01000007.1\|WP_003733194.1\|21294_21945_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.91243e-61
NZ_JNGP01000007.1\|WP_003721294.1\|27657_28929_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NZ_JNGP01000007.1\|WP_003721303.1\|37479_38295_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50

>NZ_JNGP01000007.1|WP_003721295.1|29068_30004_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NZ_JNGP01000007.1|WP_003721294.1|27657_28929_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NZ_JNGP01000007.1|WP_003721293.1|27349_27643_+|PTS-sugar-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NZ_JNGP01000007.1|WP_003721292.1|26287_27334_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NZ_JNGP01000007.1|WP_003721291.1|25640_26291_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNDELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NZ_JNGP01000007.1|WP_003721290.1|25231_25630_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NZ_JNGP01000007.1|WP_003721289.1|24747_25215_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQDKEKLLTEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NZ_JNGP01000007.1|WP_003733192.1|24117_24720_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NZ_JNGP01000007.1|WP_003733193.1|22053_24114_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NZ_JNGP01000007.1|WP_003733194.1|21294_21945_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPTILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALVGADFVAPYVNRMSAANIDPFKEISQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>NZ_JNGP01000007.1|WP_009930754.1|30918_31497_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NZ_JNGP01000007.1|WP_003733188.1|31603_32284_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLSFFPESLNVFHWHQDTFALPAGATRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILQIDEAFITPGKYVQSVEVMQEKDVPEDNKQMLEAILDYLINPKTI
>NZ_JNGP01000007.1|WP_003721298.1|32308_32668_-|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NZ_JNGP01000007.1|WP_003733187.1|32674_33133_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTAAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NZ_JNGP01000007.1|WP_031668100.1|33514_35350_+|lmo0514-family-class-1-internalin
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITEDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_JNGP01000007.1|WP_003721301.1|35450_35882_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_JNGP01000007.1|WP_003733185.1|35928_37359_-|CapA-family-protein
MKRRTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPIKKISPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKADEKALGKVYPDFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYNNCLPWFKSDDYTVINAESAFTNATKAENKMWRIKSDPAHVAFLPASGVDAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NZ_JNGP01000007.1|WP_003721303.1|37479_38295_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_JNGP01000007.1|WP_003721311.1|38575_38944_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVVVLLV
>NZ_JNGP01000007.1|WP_031644454.1|39091_40507_+|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGMGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_JNGP01000007_1	1.4\|30463\|36\|NZ_JNGP01000007\|PILER-CR,CRT	30463-30498	36	NZ_JNGP01000007.1	181553-181588	2	0.944

1. spacer 1.4|30463|36|NZ_JNGP01000007|PILER-CR,CRT matches to position: 181553-181588, mismatch: 2, identity: 0.944

acaataataggatattttggatttgtctgcgttcct	CRISPR spacer
acgataataggatattttggatttgcctgcgttcct	Protospacer
**.**********************.**********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_JNGP01000007_1	1.3\|30399\|35\|NZ_JNGP01000007\|PILER-CR,CRT	30399-30433	35	NC_021539	Listeria phage LP-030-2, complete genome	18926-18960	1	0.971
NZ_JNGP01000007_1	1.3\|30399\|35\|NZ_JNGP01000007\|PILER-CR,CRT	30399-30433	35	KJ094023	Listeria phage LP-101, complete genome	22882-22916	1	0.971
NZ_JNGP01000007_1	1.7\|30399\|36\|NZ_JNGP01000007\|CRISPRCasFinder	30399-30434	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
NZ_JNGP01000007_1	1.7\|30399\|36\|NZ_JNGP01000007\|CRISPRCasFinder	30399-30434	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
NZ_JNGP01000007_1	1.1\|30270\|37\|NZ_JNGP01000007\|PILER-CR,CRT	30270-30306	37	NC_009812	Listeria phage B025, complete genome	30705-30741	2	0.946
NZ_JNGP01000007_1	1.3\|30399\|35\|NZ_JNGP01000007\|PILER-CR,CRT	30399-30433	35	NC_009812	Listeria phage B025, complete genome	23381-23415	2	0.943
NZ_JNGP01000007_1	1.7\|30399\|36\|NZ_JNGP01000007\|CRISPRCasFinder	30399-30434	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
NZ_JNGP01000007_1	1.5\|30270\|38\|NZ_JNGP01000007\|CRISPRCasFinder	30270-30307	38	NC_009812	Listeria phage B025, complete genome	30704-30741	3	0.921

1. spacer 1.3|30399|35|NZ_JNGP01000007|PILER-CR,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

2. spacer 1.3|30399|35|NZ_JNGP01000007|PILER-CR,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.971

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctat	Protospacer
******************* ***************

3. spacer 1.7|30399|36|NZ_JNGP01000007|CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

4. spacer 1.7|30399|36|NZ_JNGP01000007|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

5. spacer 1.1|30270|37|NZ_JNGP01000007|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.946

tttatttctcctacgcttttcttatttctgtaaataa	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataa	Protospacer
************.**************.*********

6. spacer 1.3|30399|35|NZ_JNGP01000007|PILER-CR,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

ctaaaacatccttcactgtatcaactcctttctat	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctat	Protospacer
*****************.* ***************

7. spacer 1.7|30399|36|NZ_JNGP01000007|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctata	Protospacer
*****************.* ****************

8. spacer 1.5|30270|38|NZ_JNGP01000007|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 3, identity: 0.921

tttatttctcctacgcttttcttatttctgtaaataag	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataaa	Protospacer
************.**************.*********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

163620 : 193159

Listeria_phage(44.83%)

portal,capsid,protease,terminase,tail,integrase,head

attL 167808:167822|attR 182163:182177

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023552234.1\|163620_164772_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	3.4e-87	46.3
WP_023552237.1\|164793_165507_-	hypothetical protein	A0A0B5CTT6	Listeria_phage	1.1e-35	36.1
WP_014930667.1\|165561_166062_-	hypothetical protein	A0A1S7FYX8	Listeria_phage	1.9e-13	31.9
WP_012951299.1\|166074_166401_-	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	2.5e-11	35.1
WP_023552239.1\|166574_166766_+	helix-turn-helix transcriptional regulator	Q0H243	Geobacillus_phage	4.7e-10	57.6
WP_012951301.1\|166863_167190_+	DUF771 domain-containing protein	A0A2H4J474	uncultured_Caudovirales_phage	4.9e-15	41.1
WP_023552243.1\|167362_168277_+	conserved phage C-terminal domain-containing protein	A0A1W6JNI1	Staphylococcus_phage	7.8e-58	51.5
167808:167822	attL	NA	NA	NA	NA
WP_023552245.1\|168278_168635_+	hypothetical protein	NA	NA	NA	NA
WP_023552247.1\|168631_169048_+	hypothetical protein	NA	NA	NA	NA
WP_023552249.1\|169044_169221_+	hypothetical protein	A8ATL8	Listeria_phage	1.7e-14	70.7
WP_023552251.1\|169235_169955_+	DUF2786 domain-containing protein	A0A1U9WR73	Streptococcus_virus	3.5e-21	29.7
WP_023552253.1\|169958_170261_+	hypothetical protein	A0A059T695	Listeria_phage	3.8e-22	96.2
WP_031694732.1\|170257_170659_+	hypothetical protein	A8ASP1	Listeria_phage	6.0e-39	58.2
WP_031694733.1\|170655_171141_+	pentapeptide repeat-containing protein	A0A059T6G6	Listeria_phage	2.0e-44	93.2
WP_023552261.1\|171137_171599_+	hypothetical protein	A0A0C5K8Z3	Enterococcus_phage	2.0e-09	34.2
WP_023552263.1\|171595_171979_+	hypothetical protein	A8ATZ3	Listeria_phage	5.4e-45	77.2
WP_023552266.1\|171999_172248_+	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	5.0e-28	84.0
WP_023552268.1\|172247_172829_+	DUF3310 domain-containing protein	A0A059T5J6	Listeria_phage	2.3e-76	76.3
WP_031694734.1\|172828_173308_+	single-stranded DNA-binding protein	A8ASP5	Listeria_phage	2.3e-69	83.8
WP_023552274.1\|173328_173568_+	hypothetical protein	NA	NA	NA	NA
WP_031694735.1\|173558_173744_+	hypothetical protein	NA	NA	NA	NA
WP_023552279.1\|173814_174333_+	hypothetical protein	NA	NA	NA	NA
WP_023552281.1\|174329_174872_+\|integrase	tyrosine-type recombinase/integrase	H0USV4	Bacillus_phage	2.5e-48	53.3
WP_126290679.1\|174987_175221_+	hypothetical protein	NA	NA	NA	NA
WP_031694737.1\|175490_175817_+	hypothetical protein	NA	NA	NA	NA
WP_049961622.1\|175813_176173_+	HNH endonuclease	A0A075M5R4	Enterococcus_phage	5.4e-15	46.2
WP_012951321.1\|176271_176799_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	6.1e-31	46.7
WP_012951322.1\|176767_178519_+\|terminase	terminase large subunit	A0A2H4JCI4	uncultured_Caudovirales_phage	4.1e-156	50.7
WP_023552290.1\|178525_178726_+	DUF1056 family protein	NA	NA	NA	NA
WP_060579613.1\|178728_179964_+\|portal	phage portal protein	A0A2H4JAR2	uncultured_Caudovirales_phage	3.6e-82	42.1
WP_012951324.1\|179960_180527_+\|head,protease	HK97 family phage prohead protease	A0A1D6Z2A7	Staphylococcus_phage	1.0e-44	52.2
WP_012951325.1\|180590_181760_+\|capsid	phage major capsid protein	A0A060AI54	Enterococcus_phage	2.1e-44	38.1
WP_012951326.1\|181808_182147_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_012951327.1\|182116_182437_+\|head	phage head closure protein	NA	NA	NA	NA
182163:182177	attR	NA	NA	NA	NA
WP_012951328.1\|182430_182796_+	HK97 gp10 family phage protein	B4XYP9	Lactobacillus_phage	2.4e-10	37.4
WP_014930680.1\|182798_183197_+	hypothetical protein	NA	NA	NA	NA
WP_012951330.1\|183217_183793_+\|tail	major tail protein	M1PRQ7	Streptococcus_phage	1.2e-32	42.4
WP_012951331.1\|183882_184230_+	hypothetical protein	NA	NA	NA	NA
WP_014930682.1\|184426_188626_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.2e-12	33.0
WP_014930683.1\|188618_190862_+\|tail	phage tail family protein	A0A059T682	Listeria_phage	1.2e-56	29.4
WP_031694739.1\|190867_193159_+\|tail	phage tail protein	A0A059T7Y6	Listeria_phage	4.4e-134	37.9

Anti-CRISPR protein detection

Acr_ID: NZ_JNGP01000007.1|WP_023552266.1|171999_172248_+|DUF3850-domain-containing-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_JNGP01000007.1|WP_023552266.1|171999_172248_+|DUF3850-domain-containing-protein

171999_172248_+

82 aa aa

163620-193159

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_JNGP01000007_1	Orphan	1.4\|30463\|36\|NZ_JNGP01000007\|PILER-CR,CRT	30463-30498	36	181588-181553	2

1. spacer 1.4|30463|36|NZ_JNGP01000007|PILER-CR,CRT matches to NZ_JNGP01000007 position: 181588-181553, mismatch: 2

acaataataggatattttggatttgtctgcgttcct	CRISPR spacer
acgataataggatattttggatttgcctgcgttcct	Protospacer
**.**********************.**********

10. NZ_JNGP01000001

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

25740 : 36468

Listeria_phage(40.0%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003732227.1\|25740_26469_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	4.3e-35	42.5
WP_003721755.1\|26449_26872_-\|holin	holin family protein	Q2I8E7	Bacillus_phage	1.1e-27	46.3
WP_003721754.1\|26890_27427_-	hypothetical protein	NA	NA	NA	NA
WP_003721753.1\|27423_27903_-	hypothetical protein	NA	NA	NA	NA
WP_003732224.1\|27917_28493_-	hypothetical protein	NA	NA	NA	NA
WP_003721751.1\|28507_28807_-	hypothetical protein	NA	NA	NA	NA
WP_003721750.1\|28796_29933_-\|tail	phage tail protein	A0A0B5D0G3	Listeria_phage	2.9e-46	33.5
WP_003721748.1\|29942_30761_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	5.7e-44	35.5
WP_003721747.1\|30757_32626_-	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	1.7e-19	45.3
WP_020246385.1\|32612_33017_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	8.2e-20	43.7
WP_003740132.1\|33058_33361_-	hypothetical protein	NA	NA	NA	NA
WP_003721744.1\|33408_33921_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_020246384.1\|33933_34323_-	DUF5072 family protein	NA	NA	NA	NA
WP_003721742.1\|34601_35018_-	hypothetical protein	NA	NA	NA	NA
WP_031668171.1\|35029_35458_-	hypothetical protein	A8ATZ8	Listeria_phage	3.0e-12	45.7
WP_003721740.1\|35674_36010_+	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003721739.1\|36015_36468_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9

DBSCAN-SWA_2

252193 : 262224

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003725314.1\|252193_253648_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.9e-50	30.3
WP_072215787.1\|253675_253984_-	hypothetical protein	NA	NA	NA	NA
WP_003732119.1\|254162_255773_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.4e-46	29.7
WP_003732118.1\|255830_256361_+	ADP-ribose-binding protein	A0A0K1L687	Scale_drop_disease_virus	5.2e-30	50.0
WP_003722118.1\|256647_258114_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.0e-97	40.0
WP_003732117.1\|258274_260047_+	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	6.3e-80	37.1
WP_003722116.1\|260070_262224_+	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.0e-44	34.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

11. NZ_JNGP01000010

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

81897 : 89741

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722610.1\|81897_82857_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7
WP_009924988.1\|82975_83959_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.1e-52	38.4
WP_020246727.1\|83975_85037_+	galactose mutarotase	NA	NA	NA	NA
WP_020246726.1\|85078_86809_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.3e-175	54.0
WP_010990001.1\|86916_87792_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
WP_003722605.1\|87793_88762_+	YvcK family protein	A1IMD5	Streptococcus_phage	6.7e-68	43.3
WP_003722604.1\|88769_89741_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4

DBSCAN-SWA_2

93659 : 102801

Listeria_phage(86.67%)

integrase

attL 91416:91428|attR 98703:98715

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
91416:91428	attL	NA	NA	NA	NA
WP_003722600.1\|93659_94256_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	6.6e-58	57.4
WP_003722599.1\|94412_95849_+	polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	2.3e-24	36.3
WP_003731216.1\|96124_97255_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	9.8e-212	100.0
WP_003731217.1\|97318_97828_-	hypothetical protein	A8ATX3	Listeria_phage	2.6e-87	100.0
WP_003731218.1\|97854_98346_-	hypothetical protein	A8ATX4	Listeria_phage	2.6e-92	100.0
WP_015987417.1\|98377_98686_-	helix-turn-helix transcriptional regulator	A8ATX5	Listeria_phage	9.3e-48	100.0
WP_003731220.1\|98834_99086_+	helix-turn-helix transcriptional regulator	A8ATX6	Listeria_phage	7.6e-40	100.0
98703:98715	attR	NA	NA	NA	NA
WP_015987418.1\|99089_99326_+	hypothetical protein	A8ATX7	Listeria_phage	1.1e-37	100.0
WP_003731222.1\|99322_99676_+	hypothetical protein	A8ATX8	Listeria_phage	9.9e-54	100.0
WP_003731223.1\|99653_100196_-	hypothetical protein	A8ATX9	Listeria_phage	2.8e-95	100.0
WP_015987419.1\|100259_101033_+	phage repressor protein/antirepressor Ant	A8ATY0	Listeria_phage	1.1e-140	100.0
WP_015987420.1\|101154_101679_+	hypothetical protein	A8ATY1	Listeria_phage	6.3e-89	100.0
WP_003731810.1\|101685_101922_+	DUF771 domain-containing protein	A8ATY2	Listeria_phage	1.9e-40	100.0
WP_003731809.1\|102029_102218_+	hypothetical protein	A8ATY3	Listeria_phage	4.5e-29	100.0
WP_188186120.1\|102453_102801_+	YqaJ viral recombinase family protein	A0A0B5CYQ7	Listeria_phage	3.7e-61	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage