CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_QTWH01000054	Ruminococcus sp. AF25-13 AF25-13.Scaf54, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000021	Ruminococcus sp. AF25-13 AF25-13.Scaf21, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000047	Ruminococcus sp. AF25-13 AF25-13.Scaf47, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000051	Ruminococcus sp. AF25-13 AF25-13.Scaf51, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000036	Ruminococcus sp. AF25-13 AF25-13.Scaf36, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000025	Ruminococcus sp. AF25-13 AF25-13.Scaf25, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000026	Ruminococcus sp. AF25-13 AF25-13.Scaf26, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000056	Ruminococcus sp. AF25-13 AF25-13.Scaf56, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000023	Ruminococcus sp. AF25-13 AF25-13.Scaf23, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000053	Ruminococcus sp. AF25-13 AF25-13.Scaf53, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000017	Ruminococcus sp. AF25-13 AF25-13.Scaf17, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000006	Ruminococcus sp. AF25-13 AF25-13.Scaf6, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000057	Ruminococcus sp. AF25-13 AF25-13.Scaf57, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000016	Ruminococcus sp. AF25-13 AF25-13.Scaf16, whole genome shotgun sequence	0 crisprs	c2c9_V-U4	0	0	1	0
NZ_QTWH01000046	Ruminococcus sp. AF25-13 AF25-13.Scaf46, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000001	Ruminococcus sp. AF25-13 AF25-13.Scaf1, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000041	Ruminococcus sp. AF25-13 AF25-13.Scaf41, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000010	Ruminococcus sp. AF25-13 AF25-13.Scaf10, whole genome shotgun sequence	1 crisprs	RT,WYL	0	0	3	1
NZ_QTWH01000042	Ruminococcus sp. AF25-13 AF25-13.Scaf42, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000011	Ruminococcus sp. AF25-13 AF25-13.Scaf11, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000004	Ruminococcus sp. AF25-13 AF25-13.Scaf4, whole genome shotgun sequence	1 crisprs	NA	2	0	0	0
NZ_QTWH01000058	Ruminococcus sp. AF25-13 AF25-13.Scaf58, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000007	Ruminococcus sp. AF25-13 AF25-13.Scaf7, whole genome shotgun sequence	0 crisprs	DinG	0	0	0	0
NZ_QTWH01000013	Ruminococcus sp. AF25-13 AF25-13.Scaf13, whole genome shotgun sequence	0 crisprs	csa3	0	0	0	0
NZ_QTWH01000040	Ruminococcus sp. AF25-13 AF25-13.Scaf40, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000055	Ruminococcus sp. AF25-13 AF25-13.Scaf55, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000008	Ruminococcus sp. AF25-13 AF25-13.Scaf8, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000044	Ruminococcus sp. AF25-13 AF25-13.Scaf44, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000005	Ruminococcus sp. AF25-13 AF25-13.Scaf5, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000043	Ruminococcus sp. AF25-13 AF25-13.Scaf43, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000038	Ruminococcus sp. AF25-13 AF25-13.Scaf38, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000033	Ruminococcus sp. AF25-13 AF25-13.Scaf33, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_QTWH01000030	Ruminococcus sp. AF25-13 AF25-13.Scaf30, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000031	Ruminococcus sp. AF25-13 AF25-13.Scaf31, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000048	Ruminococcus sp. AF25-13 AF25-13.Scaf48, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000059	Ruminococcus sp. AF25-13 AF25-13.Scaf59, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000049	Ruminococcus sp. AF25-13 AF25-13.Scaf49, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000039	Ruminococcus sp. AF25-13 AF25-13.Scaf39, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000027	Ruminococcus sp. AF25-13 AF25-13.Scaf27, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000035	Ruminococcus sp. AF25-13 AF25-13.Scaf35, whole genome shotgun sequence	0 crisprs	WYL	0	0	1	0
NZ_QTWH01000024	Ruminococcus sp. AF25-13 AF25-13.Scaf24, whole genome shotgun sequence	1 crisprs	cas3,cas5,cas8c,cas7,cas4,cas1,cas2	0	8	0	0
NZ_QTWH01000052	Ruminococcus sp. AF25-13 AF25-13.Scaf52, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000009	Ruminococcus sp. AF25-13 AF25-13.Scaf9, whole genome shotgun sequence	0 crisprs	WYL	0	0	0	0
NZ_QTWH01000018	Ruminococcus sp. AF25-13 AF25-13.Scaf18, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000050	Ruminococcus sp. AF25-13 AF25-13.Scaf50, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000028	Ruminococcus sp. AF25-13 AF25-13.Scaf28, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000060	Ruminococcus sp. AF25-13 AF25-13.Scaf60, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000003	Ruminococcus sp. AF25-13 AF25-13.Scaf3, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000019	Ruminococcus sp. AF25-13 AF25-13.Scaf19, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000037	Ruminococcus sp. AF25-13 AF25-13.Scaf37, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000029	Ruminococcus sp. AF25-13 AF25-13.Scaf29, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000015	Ruminococcus sp. AF25-13 AF25-13.Scaf15, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_QTWH01000032	Ruminococcus sp. AF25-13 AF25-13.Scaf32, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000034	Ruminococcus sp. AF25-13 AF25-13.Scaf34, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_QTWH01000012	Ruminococcus sp. AF25-13 AF25-13.Scaf12, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_QTWH01000045	Ruminococcus sp. AF25-13 AF25-13.Scaf45, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000020	Ruminococcus sp. AF25-13 AF25-13.Scaf20, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_QTWH01000014	Ruminococcus sp. AF25-13 AF25-13.Scaf14, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_QTWH01000002	Ruminococcus sp. AF25-13 AF25-13.Scaf2, whole genome shotgun sequence	0 crisprs	cas3,DEDDh,DinG	0	0	0	0
NZ_QTWH01000022	Ruminococcus sp. AF25-13 AF25-13.Scaf22, whole genome shotgun sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_QTWH01000010_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_QTWH01000010_1

69859-69967

Orphan

Consensus_repeat	Method
AGAAGGAGAACGATGAACTGAAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_QTWH01000010_1

>merge|NZ_QTWH01000010|1|69859-69967|CRISPRCasFinder
AGAAGGAGAACGATGAACTGAAAGCCAAACTGGAAGAGGCTACCCTGTATGCGGAGGATGCAGACAAGAAGATTACTAAGCTTCAGAAGGAGAACGATGAACTGAAAGC

>NZ_QTWH01000010|1|1|69859-69967|CRISPRCasFinder
AGAAGGAGAACGATGAACTGAAAGC	CAAACTGGAAGAGGCTACCCTGTATGCGGAGGATGCAGACAAGAAGATTACTAAGCTTC
AGAAGGAGAACGATGAACTGAAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_QTWH01000010.1\|WP_064786122.1\|71173_71551_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371382
NZ_QTWH01000010.1\|WP_064786144.1\|62772_64173_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273684
NZ_QTWH01000010.1\|WP_117963903.1\|66898_67393_+\|DUF2829-domain-containing-protein	unknown	unknown	gnl\|CDD\|378590
NZ_QTWH01000010.1\|WP_117963883.1\|64178_65636_+\|phage-capsid-protein	unknown	unknown	gnl\|CDD\|130605
NZ_QTWH01000010.1\|WP_117963886.1\|68050_68737_+\|phage-scaffolding-protein	unknown	unknown	gnl\|CDD\|377714
NZ_QTWH01000010.1\|WP_117687942.1\|72533_72965_+\|AP-endonuclease	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117687944.1\|73802_77336_+\|phage-tail-tape-measure-protein	unknown	unknown	gnl\|CDD\|273790
NZ_QTWH01000010.1\|WP_117963881.1\|60049_61447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117963887.1\|70694_71174_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117963885.1\|67404_67716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_064786130.1\|70074_70266_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117963884.1\|65648_66926_+\|phage-minor-capsid-protein	unknown	unknown	gnl\|CDD\|377615
NZ_QTWH01000010.1\|WP_117687941.1\|71992_72514_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117687943.1\|72961_73570_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369109
NZ_QTWH01000010.1\|WP_064786146.1\|62327_62789_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117687945.1\|77338_78052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368574
NZ_QTWH01000010.1\|WP_064786135.1\|68752_69649_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_064786119.1\|71559_72003_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000010.1\|WP_117963882.1\|61392_62319_+\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|319246
NZ_QTWH01000010.1\|WP_064786126.1\|70309_70711_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153445

Protein	Function_ID	Function_description	E-value
NZ_QTWH01000010.1\|WP_064786122.1\|71173_71551_+\|hypothetical-protein	gnl\|CDD\|371382	pfam11114, Minor_capsid_2, Minor capsid protein. Most of the members of this family are annotated as being minor capsid proteins. The genomes carrying the genes usually have three similar proteins adjacent to each other, hence this one being named as No.2.	4.49242e-06
NZ_QTWH01000010.1\|WP_064786144.1\|62772_64173_+\|hypothetical-protein	gnl\|CDD\|273684	TIGR01547, Uncharacterized_protein_YqaT, phage terminase, large subunit, PBSX family. This model detects members of a highly divergent family of the large subunit of phage terminase. All members are encoded by phage genomes or within prophage regions of bacterial genomes. This is a distinct family from pfam03354. [Mobile and extrachromosomal element functions, Prophage functions].	1.13667e-11
NZ_QTWH01000010.1\|WP_117963903.1\|66898_67393_+\|DUF2829-domain-containing-protein	gnl\|CDD\|378590	pfam11195, DUF2829, Protein of unknown function (DUF2829). This is a uncharacterized family of proteins found in bacteria and bacteriphages.	4.35045e-22
NZ_QTWH01000010.1\|WP_117963883.1\|64178_65636_+\|phage-capsid-protein	gnl\|CDD\|130605	TIGR01542, minor_structural_protein_gp61, phage portal protein, putative, A118 family. This model represents a family of phage minor structural proteins. The protein is suggested to be the head-tail connector, or portal protein, on the basis of its position in the phage gene order, its presence in mature phage, its size, and its conservation across a number of complete genomes of tailed phage that lack other candidate portal proteins. Several other known portal protein families lack clear homology to this family and to each other. [Mobile and extrachromosomal element functions, Prophage functions].	9.18568e-30
NZ_QTWH01000010.1\|WP_117963886.1\|68050_68737_+\|phage-scaffolding-protein	gnl\|CDD\|377714	pfam06810, Phage_GP20, Phage minor structural protein GP20. This family consists of several phage minor structural protein GP20 sequences of around 180 residues in length. The function of this family is unknown.	9.89005e-08
NZ_QTWH01000010.1\|WP_117687944.1\|73802_77336_+\|phage-tail-tape-measure-protein	gnl\|CDD\|273790	TIGR01760, COG5283:_Phage-related_tail_protein, phage tail tape measure protein, TP901 family, core region. This model represents a reasonably well conserved core region of a family of phage tail proteins. The member from phage TP901-1 was characterized as a tail length tape measure protein in that a shortened form of the protein leads to phage with proportionately shorter tails. [Mobile and extrachromosomal element functions, Prophage functions].	4.24164e-59
NZ_QTWH01000010.1\|WP_117687943.1\|72961_73570_+\|hypothetical-protein	gnl\|CDD\|369109	pfam06854, Phage_Gp15, Bacteriophage Gp15 protein. This family consists of bacteriophage Gp15 proteins and related bacterial sequences. The function of this family is unknown.	1.50921e-74
NZ_QTWH01000010.1\|WP_117963882.1\|61392_62319_+\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|319246	cd16387, ParB_N_Srx, ParB N-terminal domain and sulfiredoxin protein-related families. The ParB N-terminal domain/Sulfiredoxin (Srx) superfamily contains proteins with diverse activities. Many of the families are involved in segregation and competition between plasmids and chromosomes. Several families share similar activities with the N-terminal domain of ParB (Spo0J in Bacillus subtilis), a DNA-binding component of the prokaryotic parABS partitioning system. Also within this superfamily is sulfiredoxin (Srx; reactivator of oxidatively inactivated 2-cys peroxiredoxins), RepB N-terminal domain (plasmid segregation replication protein B like protein), nucleoid occlusion protein, KorB N-terminal domain partition protein of low copy number plasmid RK2, irbB (immunoglobulin-binding regulator that activates eib genes), N-terminal domain of sopB protein (promotes proper partitioning of F1 plasmid), fertility inhibition factors OSA and FiwA,DNA sulfur modification protein DndB, and a ParB-like toxin domain. Other activities includes a StrR (regulator in the streptomycin biosynthetic gene cluster), and a family containing a Pyrococcus furiosus nuclease and putative transcriptional regulators sbnI (Staphylococcus aureus siderophore biosynthetic gene cluster ). Nuclease activity has also been reported in Arabidopsis Srx.	5.09847e-09
NZ_QTWH01000010.1\|WP_064786126.1\|70309_70711_+\|hypothetical-protein	gnl\|CDD\|153445	cd08053, Yqbg, Putative Head-Tail Connector Protein Yqbg from Bacillus subtilis and similar proteins. The uncharacterized Bacillus subtilis Yqbg protein, whose gene is part of the unusual genetic element called skin, shows a similar structure to the connector proteins gp6 and gp15 from bacteriophage HK97 and SPP1, respectively. gp6 and gp15 are critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. They form dodecameric ring structures that comprise the middle ring of the connector, located between the portal protein (attached to the head) and the gp7/gp16 ring (attached to the tail). The Yqbg gene is surrounded with genes similar to genes in the Bacillus subtilis prophage-like element PBSX, which encode for proteins comprising contractile-tailed phage-like particles that are produced upon mitomycin C treatment. Yqbg likely acts as a head-tail connector protein, similar to gp6 and gp15, of the PBSX-like prophage encoded in the skin element.	1.78936e-20
NZ_QTWH01000010.1\|WP_117687945.1\|77338_78052_+\|hypothetical-protein	gnl\|CDD\|368574	pfam05709, Sipho_tail, Phage tail protein. This family consists of several Siphovirus and other phage tail component proteins as well as some bacterial proteins of unknown function.	0.00335082
NZ_QTWH01000010.1\|WP_117963884.1\|65648_66926_+\|phage-minor-capsid-protein	gnl\|CDD\|377615	pfam06152, Phage_min_cap2, Phage minor capsid protein 2. Family of related phage minor capsid proteins.	2.1086e-115

>NZ_QTWH01000010.1|WP_064786135.1|68752_69649_+|hypothetical-protein
MAKLNYATEYLQTLEQMFPYVLYFGDLFATPNNGRFRWVNSRVIEVPTISTTGRTDGDRDTIGTRKRNYNNEWKPLTLENHRQWQTLVHPRDIAETKGVVAIGNITKVYNEEQKFPEMNAYCISKLYADWTTDGAKTAHSEVLTEENVLTVFDEMMKNMDNKRVPRAGRILYVTPDVRTLINNAKQIYRTVDVGSRSDAIKRAINSIDDVKIPESVPSDMMKTKYDFTEGWKVDSTAKQINMALVHPAAVITPISYEFAQLDPPSAGSQGKYDYFEESFEDVFILPHKMDAIDFHVSV
>NZ_QTWH01000010.1|WP_117963886.1|68050_68737_+|phage-scaffolding-protein
MAYEFLKKLFGTPKDGEEPKAMTYAELEAAIDADKKIQVVDVKAGGYVSKEKLDAKITELDGVKQQLSDANTTIQSYKDMDIDGIKQSAKDWETKYTQETQKLTAQLAAQERTHALDMFMGGYKFSSKPAENGVRAEFEKKNFTLEDGKFLGGDEFMKSLMENDDYKGAFVIEDDNNPEDDSHEDEERKPFFARGVGGTGGAGGEGVKGKEAPFNPFGFNLIRQPDKN
>NZ_QTWH01000010.1|WP_117963885.1|67404_67716_+|hypothetical-protein
MKKLFISQPMKGKSDEDILAERQKAIKSAEEKIGEPVEVIDSFFQEAPVDAKPLWFLGKSLELLAGADIAYFAKGWQEARGCKIENTCAIEYGIPVIEDYTAE
>NZ_QTWH01000010.1|WP_117963903.1|66898_67393_+|DUF2829-domain-containing-protein
MLFRKAFELMKQGMKVKLPSWAGYWYWSKEKQTIIMHTKDGIDMDIRETQIPDYTFSNIASDEWTLADSKNCPELGGEATFSFGEAIKYLKRGMKVARKGWNGKKQYIQLATGISYKTADGDIVNCEHDAIGNMAIAFVGTSGVQMGWLASQADMLADDWVFAD
>NZ_QTWH01000010.1|WP_117963884.1|65648_66926_+|phage-minor-capsid-protein
MLTPEYLNSFSSGYLGMCDVLNEQIIRDVARRIAKTGRITPTAEWQLKQAKQSGALMDDVIREVGVLTGKSDTEILRLFQDAGLSGMLQDAKPLLQAGKLKTSNIVLSGAMQRTMEAAAEKCRGEIGNLTLTTAIATQQEYMQTLNAAYMKVTSGAFSYQEAIRQAIRDAAVKGTSVMYDSGYISKLDTAIRTALLTGVNQTAGKLTELYASELGAEYYETTAHAGARPSHSVWQGKVFKIEGTAPGYENFYEATGYGTGAGLCGWNCRHSFYPYWPGISKPAYTKDDLEDYSRPKYSFAGNLLTEYECMQKQREYERAVREYKRILAAYDSYIQTVQSEADRAYFREEFQKESVKLKEKESQMKDFCKQTGRSADTARTQVSAVYDGNGNLVSFNRSVSGKAVWANKKAKQGGNKTCYLEKHLN
>NZ_QTWH01000010.1|WP_117963883.1|64178_65636_+|phage-capsid-protein
MRIANILRKVLRRLVPNNSVEKALGVDICESGVMQNAIELWHNMYKNEPPWRGGKDNVIPLNLPAAISEEFARLILTEFSMEVTGSPMAAFINEQLKDQLTDLNKFVEMYCAGGAIAVKPFVTNIDENGKPTAIELDFVKAVDFFPCAFNNKGEITAAVFVEGKKIGDYLYTRLEYHELTGMTYTIINKAFKSEEIYQYNDDGTYAVRDRFRKEVPLSEVDEWAGLSEEPVIIGNIDKPLFAYIKVPKANNIDTDSPFGVSVFSRATEIIEQADIQYGRVLWEYKATEAAILGDSELFQTDKHGKPVLPAGQERMFKTFDFDNADGTNKGLLKEYAPQIRHEALFQGLNKLLMKIEFLVGLAYGTLSEPTDIEKTAYEIRVSKQRSYHTVTAMQDAWHKGFEKIIYAMRVLALLYDMVPDGETELNCNWGDGVLEDTEAEYQRRWSMVVAGKLKTEAFLAWYFGCSEEEAKNMMPEPVARFPTEE
>NZ_QTWH01000010.1|WP_064786144.1|62772_64173_+|hypothetical-protein
MAAKNKGLSNPYVKVNRRKRIGFNFSDKHKRYIKNCANSTYNILEGAVRSGKTVDNVFAFAHELKTTKDRIHLATGSTMANAKLNIGDANGFGLEYIFRGQCRWTQYKGNDCLLINGPDTGYKDKIVIFAGGAASDSYKKIRGNSYGMWIATEINLHHDNTIKEAFNRQLAAKNRKIFWDLNPDHPKAAIYVDYIDKYAEKAAKGELLGGYNYEHFNIFENINIPKQRIAEIVSQYDKDSIWYIRDIEGKRSIAEGLIYVKLATSIAAEDDEYIVPLEETIDMAKRGEFIELNIGVDFGGNGSGHAFVASGITQGYEKLYVLSSEWHDADGTDPDDLNRMFMKFVEKILDRYGFITNVYCDSAELVLKRGLQKAMIEAELGNINVTNAAKCKITDRIFTMTTLSATGRVFFTPDCESVLEAISMAVWNPKKMELERLDDGTSDIDSLDAMEYSFEKRIKKFIKKTG
>NZ_QTWH01000010.1|WP_064786146.1|62327_62789_+|hypothetical-protein
MAAKQKYDERFVKIAKVLCMRGGTDEDLADAFEVSPRTINRWKKDYPEFAEALAAGKEYADAEVELSLYKRAKGSKKKTKVTRKIIEMDKDGNTKPAKIETVETEEDIIPDVGACCFWLKNRRPDIWRDKQEIGLYEIEDMEGIEADIYGGEE
>NZ_QTWH01000010.1|WP_117963882.1|61392_62319_+|ParB-N-terminal-domain-containing-protein
MVKEGKTVAEEQKAKYEIIYDMGTELYIAKVQLAELKEQDINARIMKNEMQDQLTANIKNRGQLESLPLIALMGEKLEIISGHHRVKSAREAGLKEIIVILDKSGLTRSKAASKQLAHNAISGFDDESTLREIVKLMDNVDDMMESYIGKEILEEPLEQFDKLNTPAVQFDFKTIAFAFLPNQIRDLDALMKNLNGSCAEIIGVAAYEQCEKFVETLDKYQQFTDIRNVGAAVHSMIDAANEKMDDAGFDSDMDWTYLAKVFGSAAIPVESAEVIKKALKKAEKDGTITSKNKWQMIEYWAADYLAGK
>NZ_QTWH01000010.1|WP_117963881.1|60049_61447_+|hypothetical-protein
MAFFRDPGEMFLGCLGTVEQRYLVNLIKNAAKNGYTRFVEPCAGTFAMSNLAIQNGYKPEQIETSDASMMSSVMGYAITGKPLDELEIHAQGFSDEELLDPAVALYAQMYLRTSKTAGNEYFFNLLKDLRDRREEHIEHIRQSLENIKKEMYGMTYRPLDMWDHLDEVLDDPHTLVIANPPTYFSGYEKFYDTQGKMTWKEPEYKLFDPETGHVELFDRCMNANALVVCYQEKRTGEAVGEPIFARAGTRADLNSYITSNRGEEAAALAEGRKIKRPSESKLAPIACSMLPRDYEITEKSKVQIISIKAAEAQYYRQLWTHNFVGSSATFNRAVLIDGMVSGVFGISKMQATSLFIWYVMKVPHTTYRLGRLLYMLAQNHCFTETLLDDLEREKVTKVRTAMLTKYPENKEVRGIMKLVNRQKDKNNGFKLTYEAELTDRTEQETLEEWLRRERQWQKSRKQNMK
>NZ_QTWH01000010.1|WP_064786130.1|70074_70266_+|hypothetical-protein
MYLATKDGSSCRIPERKAAYYKSMGYSLESLEPEVRTGTSSPKEKKTGKKDSATQEGVNPANS
>NZ_QTWH01000010.1|WP_064786126.1|70309_70711_+|hypothetical-protein
MVQEDVRRPYVDFTYYKNDYGGTQIKTENDFKRVENISEAFVNQVTFGRIARLSSIVDSIKDAICCVADTVAVQNEKREAVVKSESNDGYSISYADAMNDTALHNEMYRAVRSYLANTGLLNRGWVKEYDDKQ
>NZ_QTWH01000010.1|WP_117963887.1|70694_71174_+|hypothetical-protein
MTTNSDVTIFNLRIGADRREKLCATRIMGVSWYGTKGETVSDTDRRDKAKCVIRIPVTATVEAGKQYISEEKYKKLSDEEAERYWTIQKGAYIVRGQYVVAGQRLFDTFSFRQGIILKETIEELAKLRQHDEDFVTVTEYADNTIRGTDRTKHWRIGGA
>NZ_QTWH01000010.1|WP_064786122.1|71173_71551_+|hypothetical-protein
MALKKITTPKGSIINSGNGKAELTWNQNFAAKRNAQFSRKQMFVDSEVLRRCSPRVPFQTGMLEKSGKLGTDVGSGEVDYIAPYAAMQYYGTADTRPYDANRGAHWFERMKVAEKEDILRGADKI
>NZ_QTWH01000010.1|WP_064786119.1|71559_72003_+|hypothetical-protein
MEVNSVLEGITEYFLKCPLLKDGVFRVDALGPDPVEYTIETGIFDPVIQRYVDGSSERQYQFQFGSREFYSMDRVQNIENSTFYEEFADWVEENSMAGNLPELPEGMCAEEIEVLSPGYIFDGAMKNARYQISLRLLYFKEASKNGR
>NZ_QTWH01000010.1|WP_117687941.1|71992_72514_+|hypothetical-protein
MAGNVSGAREVVQRHQFADYLNIGTSEKPNWVLMGVGFTTLDETFGAESESEKYVCEPSSSSSVVSYTSVFPFEARLIKSQDAVNALYHVGRNHLTGSDAEFEYCRVELWDQKQNASAPVANTFAARKFLVSAEVSGVSGEKKQSMSGNLNAVGDPLDGYFNTESKTFEEAAA
>NZ_QTWH01000010.1|WP_117687942.1|72533_72965_+|AP-endonuclease
MSMLKICGQELELDLFDADTMEVYEKSMDKVVKRAEETKKHTELSNADGIREMCGIVKDFFDEVFGGGTAEKLFKGKNNLAICMDAFGIVSSEAGKMKGQVNAITNKYNMNRAQRRQEGKKNKHGKNGAVVTPIGNASGRDNS
>NZ_QTWH01000010.1|WP_117687943.1|72961_73570_+|hypothetical-protein
MNHNMLVDYLPETVEIEGTEYAIETNFRTFILFEMMMQDPELSDAEKARQGLELVYPEIPENLDAAVDGLLWFYAGGKRWREKRAGAVEGAAEVQRIYSFEHDDDYIYSAFLTQYHIDLQDIEYLHWWKFKALLRTLSSDLEFSKIMEYRSVDIDATMTKEQRDFYRRKKELYALPLPADEEEKVDAIAEALMNGGDLTGLL
>NZ_QTWH01000010.1|WP_117687944.1|73802_77336_+|phage-tail-tape-measure-protein
MGYDGTLKFDTSIDSSGFQSGLSKLSGMASGAIKATTTILAGAATAVAGIGTAAIKVGSDFEAGMSKVQSISGASATEIQQLADKAKEMGAKTKFSATESAEAFQYMAMAGWKTGDMLNSIEGIMNLAAASGEDLASTSDIVTDAMTAFGLAADGTTTIIKNGYSKEVSNATHFADVLAKAASNSNTNVGMMGETFKYVAPVAGALGFSVEDCATAIGLMANSGIKASQAGTSLRSIFTRMAKPTKEVQAAMDQLGISLTNSDGSMKSLKEIMNDLRSGFAGLTEAQKAQLAASLGGQEAMSGLLAIVNASDEDYQKLTDSIYDADGAAKEMADTMNDNLQGAITLCKSALESVGIALYEEVQEPMKETVKVITSMVEDMNEAMAEKGFDGLIEAFGNSLAELAQMAMEAAPILIGVAEDLVGTFINAIMDHQEEFAEAGATVVAELVKAILNVAGDMWSAGIYLFTEFLQALSDHSEEIGRSFGEMLSKLGEAVQENLPLIIRAAKDFVAGFCEGLSEEFPGVSALIEGFLNGFIDTASTIIQGIVDVVSDLFGVIDGADPNVLEAVGYAIGVIAASIAALSVASSVLSSVKSLFKVLGTLKGGVSGLVGVIGKVVEGFALWKGGAGTLMEVLELEFPKVAGIFSSIGGAVQKVIGFFAEFGSSIAGIGSIIAGAILAVTNFVDMFVNGFSAIKEVLMVVGIALASVGAVILGAPALVAAAVAGIVAAVATAVVLIKEHWDQIVEFFKSIPEKLSELGSAISEWFSGVLDSIGEFIDSAVEWFSELPGKIMDAINSLAESFVEWGASMLETASEVVSQIIDSIVQFFTDLPYKIGYAIGFVIGTLIEWGANVINWITTNVPQMIDSIIKFFSELPGKIWNWLVNTYNKLVEWGSQMLQKAGEIASNCIDNIVKFFSELPGKIWNWLTDAFNKLVTWGSNTLQKAKEIASNTIDAIVNFFSQLPGKIWTWLSNTLQKVIQWGSDMVAKGRQAASDLCSAVINGVANLPSQMANVGYNIVMGVWNGICNAAGWFRRQVQSFFSGIVDGVKGALGIHSPSKVFADEIGKWIPPGIGVGIEAEMPDLYKQMDDEMASLGKRMQTAVNVETGKIAVDKKVSTTYKVEKEKQGVFESGDTTVEITGETHVHVDLDGREVGDATTPIVDENMARIDTHKKRGG
>NZ_QTWH01000010.1|WP_117687945.1|77338_78052_+|hypothetical-protein
MSGVGITFDETHSFRDWGLRLKKIVIGIPKAKTEYVSVPGMNGDLDLSEAQNGGVKYEMRTLKFTFGARNCSYERWSGLLSQIASDLQGISKRIILDTDKGYYYTGRCEIETEKNNDVTAEIVISCKCEPYKISVDSSDEPWKWDTFSFINGVIRNTSDITISSGSGWQKVSLDGWVHNETLRIVSNAEMKVRYRNSTYTIYTGENIMYDIVLYKGANDLYFQGTGKVTLIHRGGML

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

45958 : 55880

unidentified_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117687923.1\|45958_47692_-	recombinase family protein	H7BV64	unidentified_phage	1.2e-155	51.1
WP_117963880.1\|47744_48320_-	hypothetical protein	A0A2K9V3H4	Faecalibacterium_phage	4.3e-38	43.1
WP_117687926.1\|48307_48631_-	hypothetical protein	NA	NA	NA	NA
WP_117687927.1\|48672_49050_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_117687928.1\|49284_49704_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_101872434.1\|49732_50227_+	helix-turn-helix domain-containing protein	A0A2K9V3J3	Faecalibacterium_phage	6.3e-38	53.1
WP_064786177.1\|50360_50654_+	hypothetical protein	NA	NA	NA	NA
WP_082923073.1\|50631_50862_+	hypothetical protein	NA	NA	NA	NA
WP_117687974.1\|50881_51712_+	recombinase RecT	H7BV62	unidentified_phage	9.1e-82	58.0
WP_101872437.1\|51725_52523_+	PD-(D/E)XK nuclease-like domain-containing protein	H7BV60	unidentified_phage	3.4e-94	65.0
WP_064786171.1\|52534_53344_+	phage replisome organizer N-terminal domain-containing protein	C9WB95	Streptococcus_virus	4.0e-42	60.9
WP_064786169.1\|53343_53997_+	hypothetical protein	NA	NA	NA	NA
WP_064786167.1\|54016_54412_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_117687931.1\|54421_54850_+	RusA family crossover junction endodeoxyribonuclease	A0A2K9V3I2	Faecalibacterium_phage	3.4e-32	52.8
WP_064786165.1\|54863_55880_+	DUF1351 domain-containing protein	H7BV61	unidentified_phage	1.3e-16	26.4

DBSCAN-SWA_2

59400 : 69649

Faecalibacterium_phage(44.44%)

capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117687932.1\|59400_59901_+	hypothetical protein	A0A2K9V3G3	Faecalibacterium_phage	2.3e-19	42.9
WP_117963881.1\|60049_61447_+	hypothetical protein	A0A2K9V3N2	Faecalibacterium_phage	1.4e-151	55.9
WP_117963882.1\|61392_62319_+	ParB N-terminal domain-containing protein	A0A2K9V3J4	Faecalibacterium_phage	5.6e-96	59.0
WP_064786146.1\|62327_62789_+	hypothetical protein	C7U0V7	Enterobacteria_phage	1.7e-21	45.4
WP_064786144.1\|62772_64173_+	hypothetical protein	H7BV54	unidentified_phage	7.9e-179	67.0
WP_117963883.1\|64178_65636_+\|capsid	phage capsid protein	H7BV53	unidentified_phage	1.1e-146	52.4
WP_117963884.1\|65648_66926_+\|capsid	phage minor capsid protein	A0A2K9V3K1	Faecalibacterium_phage	4.7e-69	38.7
WP_117963903.1\|66898_67393_+	DUF2829 domain-containing protein	H7BV51	unidentified_phage	1.2e-73	79.3
WP_117963885.1\|67404_67716_+	hypothetical protein	NA	NA	NA	NA
WP_117963886.1\|68050_68737_+	phage scaffolding protein	NA	NA	NA	NA
WP_064786135.1\|68752_69649_+	hypothetical protein	H7BV50	unidentified_phage	1.7e-126	74.1

DBSCAN-SWA_3

148063 : 154667

Streptococcus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003059926.1\|148063_148390_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.1e-25	52.4
WP_117963902.1\|148405_148789_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	5.8e-31	56.8
WP_003061262.1\|148957_149545_+	helix-turn-helix transcriptional regulator	A0A0S2MVM8	Bacillus_phage	6.8e-07	49.1
WP_003062524.1\|149753_151148_+	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	2.3e-178	66.4
WP_003062030.1\|151331_152528_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.6e-146	62.0
WP_003061156.1\|152541_152676_+	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_003060793.1\|152677_152899_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	2.6e-28	86.3
WP_003060053.1\|152966_153386_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_008687105.1\|153476_153773_+	hypothetical protein	NA	NA	NA	NA
WP_003062492.1\|153691_154195_+	antirestriction protein ArdA	NA	NA	NA	NA
WP_131067665.1\|154212_154667_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.1e-49	62.0

Anti-CRISPR protein detection

Acr_ID: NZ_QTWH01000010.1|WP_064786071.1|95185_95731_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_QTWH01000010.1|WP_064786071.1|95185_95731_+|hypothetical-protein

95185_95731_+

181 aa aa

AcrIIA11

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR1286\|WP_064786071.1\|AcrIIA11\|II-A\|Verified\|Clostridiales	1.0	1	1.0

2. NZ_QTWH01000009

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_QTWH01000015

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

80537 : 90886

Bacillus_phage(22.22%)

integrase,transposase

attL 72585:72600|attR 96052:96067

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
72585:72600	attL	NA	NA	NA	NA
WP_005342931.1\|80537_81224_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-30	34.2
WP_035403278.1\|81325_82264_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.7e-37	41.1
WP_117579837.1\|82241_82937_+	ABC transporter permease	NA	NA	NA	NA
WP_054752124.1\|82952_83690_+	ABC transporter permease	NA	NA	NA	NA
WP_117570077.1\|83699_84599_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.7e-12	29.6
WP_005342894.1\|84830_85190_-	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-21	45.2
WP_117570080.1\|85612_86803_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	1.7e-41	33.1
WP_117570076.1\|86897_88541_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	4.2e-46	27.3
WP_020437242.1\|88680_89055_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.1e-15	40.4
WP_117570075.1\|89516_90539_-	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	1.5e-97	56.6
WP_117570074.1\|90535_90886_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	7.9e-19	45.4
96052:96067	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_QTWH01000033

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

42 : 8778

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117964052.1\|42_2439_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	75.9
WP_003060083.1\|2438_4649_+	MFS transporter	A0A1S5SF30	Streptococcus_phage	1.1e-187	60.1
WP_003059774.1\|4645_5653_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	1.7e-130	68.2
WP_003062215.1\|5669_6581_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	5.3e-83	53.5
WP_003061887.1\|6725_7040_+	hypothetical protein	NA	NA	NA	NA
WP_007286202.1\|7041_7251_+	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	1.1e-23	80.9
WP_003061243.1\|7265_7595_+	DUF3784 domain-containing protein	NA	NA	NA	NA
WP_003060191.1\|7610_7841_+	hypothetical protein	NA	NA	NA	NA
WP_003061398.1\|8007_8778_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-32	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_QTWH01000012

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13602 : 21418

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117500821.1\|13602_14343_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	3.0e-129	90.2
WP_117500822.1\|14339_15194_-	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	1.4e-146	90.0
WP_008976877.1\|15424_16888_-	Msr family ABC-F type ribosomal protection protein	A0A2I4R674	Erysipelothrix_phage	4.5e-233	90.7
WP_008976876.1\|17008_18226_-	macrolide efflux MFS transporter Mef(A)	A0A1B0RXG2	Streptococcus_phage	7.1e-208	95.1
WP_008976875.1\|18756_19134_-	TnpV protein	A0A1B0RXG6	Streptococcus_phage	4.8e-30	53.6
WP_008976874.1\|19563_19839_-	helix-turn-helix transcriptional regulator	I2E8Y1	Clostridium_phage	1.7e-05	36.7
WP_008976873.1\|19922_20336_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	A0A1G5SBV5	Enterococcus_phage	3.9e-33	51.5
WP_117963907.1\|20325_21105_-	FAD-dependent thymidylate synthase	NA	NA	NA	NA
WP_008976871.1\|21091_21418_-	hypothetical protein	A0A1B0WLY6	Flavobacterium_phage	1.3e-07	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_QTWH01000034

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3612 : 10493

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117964054.1\|3612_3939_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.1e-25	52.4
WP_117964055.1\|3954_4338_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	1.0e-32	58.5
WP_025579173.1\|4440_5082_+	DUF3796 domain-containing protein	NA	NA	NA	NA
WP_008787613.1\|5085_5289_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_117964056.1\|5357_6752_+	ATP-binding protein	A0A1S5SFB5	Streptococcus_phage	2.5e-177	66.2
WP_117964057.1\|6935_8132_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	4.3e-149	62.8
WP_117762157.1\|8144_8279_+	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_009265886.1\|8279_8501_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	1.2e-28	87.7
WP_117762158.1\|8671_8875_+	helix-turn-helix transcriptional regulator	B3GVX0	Streptococcus_phage	1.3e-05	39.3
WP_055061723.1\|8876_9200_+	hypothetical protein	NA	NA	NA	NA
WP_117964058.1\|9302_9599_+	conjugal transfer protein	NA	NA	NA	NA
WP_117964059.1\|9517_10021_+	antirestriction protein ArdA	NA	NA	NA	NA
WP_147340360.1\|10038_10493_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	8.7e-50	62.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_QTWH01000016

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

81270 : 91613

Streptococcus_phage(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117542084.1\|81270_82203_-	D-2-hydroxyacid dehydrogenase	M1NSB9	Streptococcus_phage	1.7e-20	30.1
WP_117836492.1\|82488_83148_+\|transposase	IS607 family transposase	Q331Z3	Clostridium_botulinum_C_phage	1.7e-54	53.6
WP_117836491.1\|83095_84259_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	2.0e-106	51.7
WP_117570023.1\|84436_84979_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	3.8e-12	46.5
WP_117570046.1\|85054_85435_+	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_015528090.1\|85532_85676_+	six-cysteine peptide SCIFF	NA	NA	NA	NA
WP_020436924.1\|85900_87301_+	thioether cross-link-forming SCIFF peptide maturase	A0A1L7N0Q5	Ralstonia_phage	9.9e-12	23.8
WP_117541910.1\|87337_89746_+	protein translocase subunit SecD	A0A1B1IVP7	uncultured_Mediterranean_phage	7.3e-23	32.2
WP_117541911.1\|89888_91613_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	9.7e-86	34.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_QTWH01000004

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_QTWH01000004_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_QTWH01000004_1

127162-127305

Orphan

Consensus_repeat	Method
GAGTTCCCCATAACTACTTTCT	CRT

3 spacers

The CRISPR arrays of NZ_QTWH01000004_1

>merge|NZ_QTWH01000004|1|127162-127305|CRT
GAGTTCCCCATAACTACTTTCTTCAAAATCATAACTATCTCGAGTTCCCCATAACTACTTTCTTCAAAATNNNNNNNNNNCGAGTTCCCCATAACTACTTTCTTCAAAATCATAACTATCTCGAGTTCCCCATAACTACTTTCT

>NZ_QTWH01000004|1|1|127162-127305|CRT
GAGTTCCCCATAACTACTTTCT	TCAAAATCATAACTATCTC
GAGTTCCCCATAACTACTTTCT	TCAAAATNNNNNNNNNNC
GAGTTCCCCATAACTACTTTCT	TCAAAATCATAACTATCTC
GAGTTCCCCATAACTACTTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_QTWH01000004.1\|WP_117540596.1\|133508_136304_+\|alpha-L-rhamnosidase	unknown	unknown	gnl\|CDD\|379971
NZ_QTWH01000004.1\|WP_117569317.1\|132093_133443_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340890
NZ_QTWH01000004.1\|WP_020436894.1\|121000_121696_+\|DUF4194-domain-containing-protein	unknown	unknown	gnl\|CDD\|372745
NZ_QTWH01000004.1\|WP_117569312.1\|125094_125811_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226425
NZ_QTWH01000004.1\|WP_117569308.1\|114553_116029_-\|DUF1846-domain-containing-protein	unknown	unknown	gnl\|CDD\|378092
NZ_QTWH01000004.1\|WP_117569318.1\|137049_137808_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_QTWH01000004.1\|WP_015529547.1\|119595_121008_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000004.1\|WP_117569309.1\|116275_118465_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_QTWH01000004.1\|WP_117569316.1\|128421_129615_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274977
NZ_QTWH01000004.1\|WP_117569310.1\|118701_119535_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_QTWH01000004.1\|WP_117540600.1\|136771_136915_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_QTWH01000004.1\|WP_117569311.1\|121661_125033_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379260
NZ_QTWH01000004.1\|WP_117569320.1\|138621_139470_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380391
NZ_QTWH01000004.1\|WP_117569315.1\|127760_128330_+\|hypothetical-protein	unknown	unknown	unknown
NZ_QTWH01000004.1\|WP_117569321.1\|139692_140985_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270452
NZ_QTWH01000004.1\|WP_117540572.1\|112665_114282_-\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NZ_QTWH01000004.1\|WP_117569313.1\|125859_127095_+\|DUF2399-domain-containing-protein	unknown	unknown	gnl\|CDD\|370769
NZ_QTWH01000004.1\|WP_117569307.1\|112012_112570_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239489
NZ_QTWH01000004.1\|WP_117569319.1\|137967_138588_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|376440
NZ_QTWH01000004.1\|WP_117540592.1\|129819_132075_+\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|185053

Protein	Function_ID	Function_description	E-value
NZ_QTWH01000004.1\|WP_117540596.1\|133508_136304_+\|alpha-L-rhamnosidase	gnl\|CDD\|379971	pfam17389, Bac_rhamnosid6H, Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.	1.80009e-124
NZ_QTWH01000004.1\|WP_117569317.1\|132093_133443_+\|MFS-transporter	gnl\|CDD\|340890	cd17332, MFS_MelB_like, Salmonella enterica Na+/melibiose symporter MelB and similar transporters of the Major Facilitator Superfamily. This family is composed of Salmonella enterica Na+/melibiose symporter MelB, Major Facilitator Superfamily domain-containing proteins, MFSD2 and MFSD12, and other sugar transporters. MelB catalyzes the electrogenic symport of galactosides with Na+, Li+ or H+. The MFSD2 subfamily is composed of two vertebrate members, MFSD2A and MFSD2B. MFSD2A is more commonly called sodium-dependent lysophosphatidylcholine symporter 1 (NLS1). It is an LPC symporter that plays an essential role for blood-brain barrier formation and function. Inactivating mutations in MFSD2A cause a lethal microcephaly syndrome. MFSD2B is a potential risk or protect factor in the prognosis of lung adenocarcinoma. MelB-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.3668e-88
NZ_QTWH01000004.1\|WP_020436894.1\|121000_121696_+\|DUF4194-domain-containing-protein	gnl\|CDD\|372745	pfam13835, DUF4194, Domain of unknown function (DUF4194).	0.000136575
NZ_QTWH01000004.1\|WP_117569312.1\|125094_125811_+\|AAA-family-ATPase	gnl\|CDD\|226425	COG3910, COG3910, Predicted ATPase [General function prediction only].	2.93137e-74
NZ_QTWH01000004.1\|WP_117569308.1\|114553_116029_-\|DUF1846-domain-containing-protein	gnl\|CDD\|378092	pfam08903, DUF1846, Domain of unknown function (DUF1846). This family of proteins are functionally uncharacterized. Some members of the family are annotated as ATP-dependent peptidases. However, we can find no support for this annotation.	0
NZ_QTWH01000004.1\|WP_117569318.1\|137049_137808_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	5.37869e-69
NZ_QTWH01000004.1\|WP_117569309.1\|116275_118465_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_QTWH01000004.1\|WP_117569316.1\|128421_129615_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|274977	TIGR04094, AraC_family_transcriptional_regulator, YSIRK-targeted surface antigen transcriptional regulator. Bacteria whose genomes encode only one protein with the YSIRK variant form of signal peptide (TIGR01168) were examined for conserved genes near that one tagged protein. This protein is found adjacent to at various classes of repetitive or low-complexity YSIRK proteins (whether unique in genome or not), in a range of species (Enterococcus faecalis X98, Ruminococcus torques, Coprobacillus sp. D7, Lysinibacillus fusiformis ZC1, Streptococcus equi subsp. equi 4047, etc). The affliated YSIRK proteins include Streptococcal protective antigen (see ) and proteins with the Rib/alpha/Esp surface antigen repeat (see TIGR02331). The last quarter of this protein has an AraC family helix-turn-helix (HTH)transcriptional regulator domain.	4.16252e-37
NZ_QTWH01000004.1\|WP_117540600.1\|136771_136915_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	6.27455e-13
NZ_QTWH01000004.1\|WP_117569311.1\|121661_125033_+\|AAA-family-ATPase	gnl\|CDD\|379260	pfam13558, SbcCD_C, Putative exonuclease SbcCD, C subunit. Possible exonuclease SbcCD, C subunit, on AAA proteins.	1.68963e-22
NZ_QTWH01000004.1\|WP_117569320.1\|138621_139470_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|380391	cd06986, cupin_MmsR-like_N, AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain. This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.	1.31164e-30
NZ_QTWH01000004.1\|WP_117569310.1\|118701_119535_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	1.01538e-33
NZ_QTWH01000004.1\|WP_117569321.1\|139692_140985_+\|extracellular-solute-binding-protein	gnl\|CDD\|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.84344e-38
NZ_QTWH01000004.1\|WP_117540572.1\|112665_114282_-\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_QTWH01000004.1\|WP_117569313.1\|125859_127095_+\|DUF2399-domain-containing-protein	gnl\|CDD\|370769	pfam09983, DUF2220, Uncharacterized protein conserved in bacteria C-term(DUF2220). This domain, found in various hypothetical bacterial proteins, has no known function. The family represents just the C-terminus.	3.73996e-08
NZ_QTWH01000004.1\|WP_117569307.1\|112012_112570_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	4.25049e-30
NZ_QTWH01000004.1\|WP_117569319.1\|137967_138588_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|376440	pfam01035, DNA_binding_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain. This domain is a 3 helical bundle.	1.23834e-33
NZ_QTWH01000004.1\|WP_117540592.1\|129819_132075_+\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	gnl\|CDD\|185053	PRK15098, PRK15098, beta-glucosidase BglX.	8.45791e-99

>NZ_QTWH01000004.1|WP_117569313.1|125859_127095_+|DUF2399-domain-containing-protein
MEWNEKNLPLAKWLIDKTNTKDYRIGNLSGMKHPKVDGDLLKTVGGRDELVRQAKVLERIPALGGKEYLHFDWREMNTDITRIDYRVEVIPRLCELIGIMDPRECQLQAISRICKLQVDVYESCLSAYCDHVLEQLNKGNTKELSKAEDEEFLKCLKALADLKEPEWKRVFSSKVFEKKNEITPSKVFERIYQGAVIEALKYSPQYDEGMSDDEILAAHGILSYSQTLEWKGAVEYCLTNRNGTASEEKIDTSSNYYGTVLNAQTLEHAIPTLRNSVEKIIVIENKANYESMEYDPKVLYLFCHGYFSPKEVRFLQMLMKTAPEEIRCYHWGDMDYGGIQIFLYNEKNIFPNLIPWKMDAPSYKAALENGKGIKLSSGKQKKLEALNAGKLETLKQCILENKMEIEQEMLI
>NZ_QTWH01000004.1|WP_117569312.1|125094_125811_+|AAA-family-ATPase
MNDQFIHGVIFDWDRIDNDSYLKKIEAFKGVEKLDFNKAITFFVGENGSGKSTLLEALAVAHGFNPEGGTKNYIFSTHDTHSELCDAIRISKGYRKEKWGYFLRAESFYNVATQEEEYADSKHPSAKYHEKSHGESFLALAQNNLHSNGLYLFDEPEAALSPQRQLTLLMQIYRFAKEGAQFFIVTHSPILLGIPDADIYCFDNGRIHLCEYEETESYQITEMFINNRQMLLDRLLTY
>NZ_QTWH01000004.1|WP_117569311.1|121661_125033_+|AAA-family-ATPase
MKEKQSKKIFTRMLMNNWGGISHKVMEFHEYVNLFSGKSGSGKSTVMDAIQVVLYGSISSTFLNKAADDAKNRRSVLSYLRGAQKDGSFNREDQDFCSQIVLEIKDTGKNTHTCIGVSFEVGKADTDIRKYCFFSHSGKIPEDEYLTEEGVPYTIAKLKKLVEARIESADNRGRGDVNRVYPSKEAYLKTVYDAIFGYVEPGRMMTMEKSAIALRMTNGTGQFIKDYMFPKSKEDTVATISDQLGAYREIKERVEDLEQRIKMLDEISQHNLALQKARADKIYVEQILKYIEIENCKAHLQSKEDDLQDILKKIEEKEEKRKSYLAEKDAYTKEQVEVEAELKASDYGQKEKELKEIENTIQLLATNSEQWRDIVKGLSAWEEDDEVSAYVSNQALHRIDDIRDGVVSEDSIEKLKQYLSDALDNINTELGDVRERIRENQKELQEKREMVEDLKNDRKPYRAELKRARQELQNMLSIQYGRTIHVNIFADLFDITDEEWKNAIEGRMGRVKHSLVTAPEYTLDAAKAFRKMKQMKGIEDVELMDTAAIVRDNPKADENTLYECVRTEESYVDTCLKRYLGRIKKCETVEELHETRDGVTKDCYSYSNYIFRHLRRNDYEKYACIGTKVSKAKLLELEEEAAKLKQEVEEDCRVEMALRAAQKFECLNQSTEQILHLSKAAEQLQDYYEKQEKLRLEVEELKRGDRTVELKKKKQELLELLKKNAEILDRIQSEVVQYAKTQGQIESNIKSFSEKINFLTEGFVVNEQLQNEVTDALKVQSEAAYKRDKTKEKDALETLEEAEREELQRSRNKFNNAYPAYGFTGIEHENDVYDKVLNQCRKDFEPKYKEEFDKQYNLVYYTLRENVIASIHGEIKAAYRHKKEINRLLAKIKFSDSIYQIDIIPAQNENGQFYEMLTAPELDSKVFDDYGFEGQLSLGEDEFYQKYEEDIKRLTEKFMPPKEEDARSLSQYRQQMEQYVDYRNYLTFSMYEKVEDENGNVRKNAVDDMAGRDSGGEGQNPKYVALLAGFAMLYMQQTNRDSKIRLVLLDEAFSKMDKERSEVCLHYARELELQLIVCVPDERLQSLIRNVDCVYGFRRHQNQVSMMHIDKGDYLDMVEGNKE
>NZ_QTWH01000004.1|WP_020436894.1|121000_121696_+|DUF4194-domain-containing-protein
MVNYMEELSVTEADNLKKTIAALFRQTCILQMKYDPVTLVPRDNLHYEICTRHRKFIEDYLSVLSCELVHDPQEHIYRLHGDGIAIEKINATVTKVILLVKLIYRDKILGEGLKATVTNLAEIREYGKNTNLINYKLTMGEWKEALYVMSKHQIIEVPGAIQNVEDETPIYIYSTINLYCGSMDITALIKEYQEDQYAEEEITEEVSEQEIQEEAEGGVEDERETVEENIY
>NZ_QTWH01000004.1|WP_015529547.1|119595_121008_+|hypothetical-protein
MKLVEKVPKDLYKIFGSKYMEFYMQFLVALYEESSQSYSLLGLTERECQMIMNERLAKMALDWSEARVDEEGELITRANMASVSLKHFEDWGWLRRDYDETLNSYVVSFPEYSQLFVELFQKLYSENDGKERESVLTVYSHLYTYSLDKEKNNEILKSALHTSRALLQMLANMQEGMRGYFDELSKQRSFRGIQEVLVKEINNSDSKKYAILTTTDSFYRYKEAVKELIEENLEKTEARKYSFETELLSEEENTRKSYRLRRMIEICEEATDMLYKISREFDAIERRYNKLIEQKTVFASRAAARIRYIMMEGVMEEDQTVALINLINESGKSEEILDKLSSKLRFSEPYKIMTEKSLYQRRENQKEKFTPQAVTPEKSQEENMTEFVLEPLYTQKEIRDFRKKNEQNGKFTVTKDTVKSIEDLEKLFMVWQHATESADSKAQIEVAQEMENEAGFRFSKLTIEGVESDG
>NZ_QTWH01000004.1|WP_117569310.1|118701_119535_+|HAD-family-hydrolase
MSCNCMTRTSQQECRGILECKAQKMQNINQDSSKKTGDIGMTKAVFFDIDDTIYDYIGAHNNTMPVMKEWAYENLGIAKEDLEKYVAEAREKADDRAGRDYAVNHNRLVRFQCMLETLGKPVFPYAYEMYNLYWDTLIDQIIPSPGIEELMKELKQRGIYIGIGSNMTSDVQYRKILKLGLGKYIDGIVTSEEAGEEKPHRKLFDLCVEKAGVMVEESIFIGDSIAHDVTGAQNIGMPVILYRPKENVNEIEWLQTEKGKCPVIAHFSQFFEAEKML
>NZ_QTWH01000004.1|WP_117569309.1|116275_118465_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MENNNKNKGPNKNRQGWGIILFTTLLVTFVVMGLYSMMQGGSASEISYDKFLKLVDNGKVESVTFTNSRINIVLTDDARKEKAEGKLTEVKENEKASADQSDSSDSTKGSEDQENAMDSLLGQISQMQGSSKSKDPDYYTGNVSDDTLVKRLDKAGVEFKAQIPDTASSLIMDIFITVILPIVLLVFMFNFLMKKMSKGGGMMGIGKSNAKMYMEKQTGVTFLDVAGEDEAKESLQEVVDFLHNPGKYTGIGAKLPKGALLVGPPGTGKTLLAKAVAGEAKVPFFSLSGSAFVEMYVGVGASRVRDLFKQAQQMAPCIVFIDEIDAIGKSRDSALGGGGNDEREQTLNQLLAEMDGFDTNKGLLVLAATNRPEVLDPALLRPGRFDRRIIVDKPDLKGRVEILKVHAKDVKMDETVNLEEIALATSGAVGSDLANMINEAAITAVKHGRQVVSQKDLFEAVEVVLVGKEKKDRIMSAEERRIVSYHEVGHALVTALQKNTEPVQKITIVPRTMGALGYVMQTPEEEKFLNTKKELEAMIVVALGGRAAEEIVFDTVTTGASNDIEQATKIARAMITQYGMSERFGLMGLESVQSRYLDGRAVRNCGEATAAEIDEEIMKMLKASYEEAKRLLSANSDALDKIAAFLIEKETITGKEFMKIFREVKGIPEPEEADGEKKEEQESGRILMKPTETQAAEPETVKEPETEKEPETQATEIQPQETVEEEKSE
>NZ_QTWH01000004.1|WP_117569308.1|114553_116029_-|DUF1846-domain-containing-protein
MKIGFDNDKYLKMQSEHIRERIGKFGGKLYLEFGGKLFDDYHASRVLPGFEPDSKLRLLKELSDQAEIVFAISAKDIEKNKIRGDLGITYDSDVIRLIGTYREQGLFVGSVVITQFSGQESALLFKNRLENLGISVYIHYNIPGYPSNIPLIVSENGYGKNDYIETSHPLVIVTAPGPGSGKMAVCLSQLYQEHQRGIEAGYAKFETFPIWNLPLKHPVNLAYEAATADLNDVNMIDPYHLEAYGVTTVNYNRDVEIFPVLNTIFEKIYGSSPYKSPTDMGVNMAGNCICDDEACREASRQEIIRRYYAALNALLKGDASEKEAEKIELLMNMEGITVSDRKVAVKALERAQETGGPAAALELEDGRIITGKTSNLLGASAALLVNVLKELAGIDHNVHIISPEAIEPIQKLKVDYLNSKNPRLHTDEILIALSASAAVNPIAELALSQLPKLKGCQAHTSVMLSSVDIKTFKKLGVQLTSEAVNEHQILS
>NZ_QTWH01000004.1|WP_117540572.1|112665_114282_-|CTP-synthase
MAVKYVFVTGGVVSGLGKGITAASLGRLLKARGYTVTMQKFDPYINIDPGTMNPVQHGEVFVTDDGAETDLDLGHYERFIDESLTKNSNVTTGKIYWSVLQKERRGDFGGGTVQVIPHITNEIKSRFYRNPAATDTEIAIIEVGGTVGDIESQPFLESIRQFQHERGAENVILIHVTLIPYLRASQEMKTKPTQASVKELQGMGIQPDIIVCRSEYPLDDAMRNKISLFCNLPADHVLQNLDVEYLYEAPLAMEKEHLAQVVCESLHLDCPEPDLADWTDMVENLRHPTQEVTVALVGKYIQLHDAYISVVEALKHGGIYTHTTVNIKWIDSETVTEENAEELFSDVSGILVPGGFGHRGVEGKITAIKYARTHNVPFLGLCLGMQLSIVEFARNVIGYKDAHSMELNPDTTHPVIHIMSDQIGIEDIGGTLRLGSYPCVLKDNSLAYKLYGKKEIEERHRHRYEVNNDYREVLEENGMSLCGLSPDSRIVEMVEIPSHPWFIATQAHPELKSRPNRPHPLFKGFVEAALENQKEKNK
>NZ_QTWH01000004.1|WP_117569307.1|112012_112570_+|phosphatase-PAP2-family-protein
MDTILQLDQNILLFIQEYIRHDWMDWFWKGITHLGDAGIFWILLTIVLLIPKKTRKAGLASALALIIGTLITNVAIKNMVARIRPYEVIQELELMIEKQKDFSFPSGHTCASFASAFAIYKCKEVFPKKWRIAAMVLATLIALSRLYVGVHYPTDVLGGLIVGLFSGWAGWKIEELIMKKKFVEK
>NZ_QTWH01000004.1|WP_117569315.1|127760_128330_+|hypothetical-protein
MKTADTIRVDQIADSVGKEIKLNPQNKRIRAYHYKNEKQEIYYFVNEDEAVYSGEIRVPYLESCYAYDAWNGTKMAQEYRAEKEDATILSMKLRLGESRIVVVEQEKETVSQLEKSLFEMMYGVEKEKIPVKKNWEIGTCRSIAYPKFSNFQPITKFEDYGKKEKKFSGFIAYRNQMERMTSELKWQLR
>NZ_QTWH01000004.1|WP_117569316.1|128421_129615_-|AraC-family-transcriptional-regulator
MSNYAYLNYMEDLFLNTASLYSWHLTPEYDFSYSNHPDSAPLKNIFSLSSCNTYMKQHFQSSMEPFFLFDDFFFLWAAVPAYTEQKKLVNIHLLGPVFSSYTSDSYIKEKMDIKNMSVKSKTELLSLIDQIPVLPTAFLSHYVCQLYYTLNDALITVNDIKLQENPMSQSKEKEDDFTASEHSPYYYETLLSQSVQDGIPFPDFSNQISSAQVGTMCPGDPLRQKKDEGIGLVTIFTRAAIQGGISFEKAYTCSDYYIQSIEAASNITEVIQLIETMYFDITNQVHEATLSAIKNPMIRECITYLDTHYREKINLEELANTLGYTKYYLSTCFKKETGVSISEYIMEKRIAYAKLMLKNPSIDMQEISDELCFANPSHFSAVFKKMTGLTPTQYRNE
>NZ_QTWH01000004.1|WP_117540592.1|129819_132075_+|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein
MERDLKKLVASMTLEEKAGMCSGADFWNTKAVERLGIPGVMMSDGPHGIRKQEGEADHLGLNESVEAVCFPAACATASSFDVDLIRQMGEILGEECQAEDLSMLLGPAVNIKRSPLCGRNFEYFSEDPYLTGKMAAAYINGVQSWDVGTSIKHFAVNNQEYKRMCVSSEVSERAFREIYLPAFEEAVKEAQPKTVMCSYNKINGVFASENEDLLTKILRDEWGFEGYVVTDWGAVNDRVKGLKAGVDLEMPSTGGYNDKKIVEAVKSGELDEKVLNRAVERMLKVIFSYVDHRHSEAVFDRDKDHEKSVEIETECAVLLENNGVLPMKEEQKIVYIGEFAEKPRYQGGGSSHINSSKVVSALEAAQEKNRNVTYVKGFSSERDEIEAQEVEKAVQAAKEADIAVVFAGLPDAFESESYDRKDMKLPACQNHLIEEVAKVQPNLVVVLHNGSPVEAPWAEQTAAILELYLGGQGVGEACDRLLYGQANPSGRLAESFPLRIEDNPSYLSFGGDGKKVDYTEGVYVGYRYYEAKKQPVRWAFGHGLSYTEFKYDHLTVSSKELDDENEIIVEVDVTNVGACAGKEVVQLYVADKNGTVNRPVKELKGFTKLFLQPRETKKAQMKISARDLSFYNEEIKDWYAPSGTYEILIGHASDDIRISCEVSFTTKKQLPFQVTGTTTIGELLADSRTAAATMELLAPLQQNGENGEEISEADQQMIQAILEGLPLKSLSIAGVTGETIEGIIYKLNELC
>NZ_QTWH01000004.1|WP_117569317.1|132093_133443_+|MFS-transporter
MGKDKIKFKEKLAYATVNFGNIPIMTIINGYLLIFYTNICGLSPAACATLFLIARILDGLNDPLVGFVIDHLPNTKFGHFRPTLIVGTILCSANFLLLWFGPMMAPSGKLAIAYVSYILLGVLFPVMDISLNSLLPVMTEDMNERNSLSSVKGLAYVVGALVVSVAAPLILGDTSNKDGYIKLILITVAVILFCSIIGTLGVKERIKPQKEKSYTIKQLFQILSQKPVYITFLVVLLYTIGNNIVSAVNTYYYTYVLGNLSWAAILTLVMCVTIFPATMIVTKFIAKYGKKKMYAVGLAIVGLCPLIRLIDVKSIPILIVSSLIAGVGSGFAAPLNYGIQADNTDYVEMTMGIRAEGAVASLSSFISKCAMGIGGAIPGYMLQMAGFNAVAEVQTQSVINVIIFCLIILPAIINVVGIGIFAKAYPLTKEKLEEQTRILQERHSADKAE
>NZ_QTWH01000004.1|WP_117540596.1|133508_136304_+|alpha-L-rhamnosidase
MGKIYAAKTNHITNPLGFYMEQIVFSWKVKECKGKKQKNARILISEKEDFSEILLDTKEENLDSCGTKVDLQTEPYTRYYWKVIVATDQEEVVESDVQFFETAKQDEPWVGKWITCGWKEGRHPIFSKPVSTEKEVERARLYICGLGLYEAYFTSNKTEKTEKIGKEYLTPYCNNYDQWIQYQTYDVTEQMKAGGELSVLLGDGWYKGRFGFSQPEKKGFFGDAWKVIAEVHIDYADGSKEVIGTDESWKVTESKISFSNIYDGEKRDDTLPDVPKAAAILAVAPKGRLMERLSLPVTVYKEMKPVELIHTPAGEQVFDLGQEITGIFRFHVKEAAGTEILIQTGEVLQDGNFYNGNLRTAKSEYHYISDGTEKEFIPYFTYYGYRYVKVSGVTDLSCDDFTALVLCSEYEKTGELETGHELVNQLISNVEWGMRGNFLDVPTDCPQRDERMGWTGDTQVFSVTASYLADTYAFYRKFLYDMYQEQLLADGMVPEVVPTFGPSKTSCAWGDAACILPWNVYLFSGDKTILEQQIDSMKAWVDYIRRVDGEHHGWRNSFHYGDWLALDRPGAKEGNVYGATDEAYIADVYYAASAQIVAKAAEALGKSELQKEYQEIADQQWTVVRDEYFTATGRCAIKTQTGLTLALKYHLSENETMTAEMLKKLFRQNKYKLNTGFVGTPLLCNVLTENGMSDIAYQLLLNEEFPGWLYEVKLGATTVWERWNSLDENGHVSSTGMNSLNHYSYGAVLEWVYRHAAGIDVTEQNPGGRKMKIHPKVNAELGYVDVSWDSASGRYQSSWKILDGNKIQLRFSVPFGCEAEISLPYVADSVYEEKENPLFVNVKEGVCLVEAGNYEVTYEAVVPLKKTYSVDSTMEDLMSNPKIRGFLASMMDVDMLPDIVYEMSLRDVAKMFAGEIGDEQEKMLNAALGQF
>NZ_QTWH01000004.1|WP_117540600.1|136771_136915_+|AraC-family-transcriptional-regulator
MLEQTTLPVKQIAQQVGYENVSHFYHLFEKYYGKTPKEVRAAGDGNN
>NZ_QTWH01000004.1|WP_117569318.1|137049_137808_+|SDR-family-oxidoreductase
MDRLKGKVAIITGGNSGVGEATAKMFAKEGATVVITARREAALEKVAEEIKAAGGEVYAVSTDISKKGNPERLMDLVIEKYGKIDILVNNAGILEEGLKPIDRFSDEDLDRIVETNEKGTMRCMRAAAQKMQAGASIVNVASIAGVKGCGGAAYVASKAAIVGVTKHTALRFQATGIRCNAICPGNIITPMTSGTNPAALDPDMIGAMSTHSNLRTPSCTAEDVANVILFFASDESKAITGQAIVTDFGAML
>NZ_QTWH01000004.1|WP_117569319.1|137967_138588_+|methylated-DNA--[protein]-cysteine-S-methyltransferase
MKTREEAVAYGLTFQDSYEDRPFKDQRWQVIRVKPSKKIFLWIYEKDEKICLNVKTDFRWRDFWRAAYPSVIPGYHQNKEHWNTIILDGSVPDKDIKQMIGESYDLVTDSPTKRIYETVKQIPKGHVATYRQVAKMAGNEKMSRAVGNALHKNLDPEHIPCFRVVNAKGELAGAFAFGGANVQAELLREDGVEVIDGKVDLKKYQM
>NZ_QTWH01000004.1|WP_117569320.1|138621_139470_-|AraC-family-transcriptional-regulator
MSDLLFSVFPNENFVDLGLYQYGWEQCAPAHSFGPAARNHYIFHYVISGTGTLFADDENGNTTEWQVKSGQGFMLFPGQVNTYIADSKLPWEYTWVEFDGLRAREIVTSAGLSPNEPVYHASSKELRNQMMDEMLYLSRHSEESPFHLIGHLYLFLDYFMRSAATVHVKQNGSIRDFYIKEALSYIEQNFQNDISVEDISAFCGLNRSYFGKIFHDTIGRSPQEFLISYRMTKATELLKITSLSIADIGNAVGYPNQLHFSRAFKNVYGMSPRNWRNENKLE
>NZ_QTWH01000004.1|WP_117569321.1|139692_140985_+|extracellular-solute-binding-protein
MYKKSNRIICMGLMLCMTSAMILGGCGQKNESSGKIEIELVQYKPEAVKTFEKIEEEFNATHDDIHLTIESPNDAMTVLKTRFIREDAPDIIGIGGDVNFSNFIDSDMLMDISDYEGLDSIKQAYLDIDKALEFVPEDGVYAVPYVANAAGVLYNRAMFKEYGWEIPETWDEFIALCEQIQSEGIQPLYFGFKDTWTCLAPWNAIAVDLAPADVCSQVNKGETTFSDEYREVAEKTQALLAYGPKDPFAYDYNGACTAFANGESAMYTIGSYAIPQIHTVNPDMDIDSFVMPANNDASENKLNSGVDLQFSVMKDCENKEAAYEVLNFLLKDENVQSYLDEQKAVPCKEGDFELASTLDGVKSFIEEGRMADYQDHYYPSEMSVDAQIQTFLMKGDVDAFLTKFDTDWKRYNRDIIRKVEDYEKEHADED

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_QTWH01000004_1	1.1\|127184\|19\|NZ_QTWH01000004\|CRT	127184-127202	19	NZ_QTWH01000009.1	137905-137923	2	0.895
NZ_QTWH01000004_1	1.3\|127265\|19\|NZ_QTWH01000004\|CRT	127265-127283	19	NZ_QTWH01000009.1	137905-137923	2	0.895

1. spacer 1.1|127184|19|NZ_QTWH01000004|CRT matches to position: 137905-137923, mismatch: 2, identity: 0.895

tcaaaatcataactatctc	CRISPR spacer
tcaaaatcataaatttctc	Protospacer
************ * ****

2. spacer 1.3|127265|19|NZ_QTWH01000004|CRT matches to position: 137905-137923, mismatch: 2, identity: 0.895

tcaaaatcataactatctc	CRISPR spacer
tcaaaatcataaatttctc	Protospacer
************ * ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_QTWH01000024

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CRISPR-Cas detection and classification

Crispr_ID: NZ_QTWH01000024_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_QTWH01000024_1

24965-27445

TypeI

Consensus_repeat	Method
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	PILER-CR
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CRISPRCasFinder
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CRT

37 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_QTWH01000024_1

>merge|NZ_QTWH01000024|1|24965-27445|PILER-CR,CRISPRCasFinder,CRT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAATATTCTATTTAGATAAAGACATTCCGAAAGAACTTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAATTACATTCTCTAAATGGTATGAACCAAACCCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGAGATTGGGGGAAAGTAATATGGCAAGCAAGACATTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATTTATGTGATCTACCGGTCTTCAATCGACTCTCCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGATTCCATGCCACCAAAGGACTGGCAAGAAGCCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAGGTATAGCAAACAAGCCATCGAAAGGTGGCTTTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATACTGTCTACTTCTGTAATTCCTACTGCATAAGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACAAGTTGTGTAAGGAACGTGATATTGATTGTAAACGTCATCCTCTTCGTGAGGATGTGAGTTGAAATCTTCTCTCATATCCATACTTCAAATTGTCTGCTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATATCACAAAGATACATTGGAAAAATTAACGATTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAAAAAGCCAATGGAACTTGCAGAACGGTTTGCAGAGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAATTGTTCTTTTAAATCCATTTTTCACTCTACGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGGTATTGACTGGTATAAGAAAGCAATGGATGATGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATTAAGCTGCCATTTTCTGCTTCCATGCTTCGATTGCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAATTGTTACGGTACTTCCTACTGTAATACCTTTGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACCCTCATTTGTGTGCCTGCCAATCAGGAACACCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACCTCCTTACGCTATTGCCGCCGTCTGGATTGTTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGTCAGTTGTCTTTTGAAAGAAAACTGCTGTGATTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATCGGCATGGCAATTAAGCAGTCTGAGACTATCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAAAAATTCCATGTTCTTCTTCCTTTCTCCGTCATGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACCCCTTTCAGAATTTCAATGAATGCTTCATAGCTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACTTGATGCATAACCGACGATATTCTTATAAACGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAGTTATCAGAAATGCAATTACAGATAACAGAAATGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATAAGAGCGCTTGAAGAAGCCATGCTAAAAATAGTCGTCCTCTTCGTGAGGATGTGAGTTGAAATGTCGAATGGGGAACTACAAAGCAACCACCACAAGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAGCCAGGCTTCCGTTAATGCGCGCTTCCAGTTTTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATACTTGCGCACGAATACATATACATCCTTTTTGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGATGATACAGAAGAAGAAAGAGAGGAAAATGTCGGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGTACAGCTATCAAAGCCAGTATCTTTGAAAATCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATTTTCTCCCTTTGAAAGTCTTACAACTGGTAAAAGTTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGACAATCTCCGGTCCCGCTTCTGCCACGATCGCGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATACCAGTCCTTCGCCGTGTCGGTTACTCTGGTAAGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATATCACTCTGCACCGATGTAGTTCAGGACTTTCTGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGCCTGCTGTTCCTTCCACTGTTCTTCGAAATCTATCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATGCATTACTCTTGACCGTTGTTGTGTTGGATGCTCCCGTCATCCTCTTCGTGAGGATGTGAGTTGAAATAACTGACTGCTTTGCAGCATTTAAGACAAGTGCTGGTCATCCTCTTCGTGAGGATGTGAGTTGAAATCTTGAAGAGTACGGCGTTAATCATCGTTGTAGCAATATGGTTCTTCTTGTGGGGAGGTGAATTGAAAT

>NZ_QTWH01000024|1|1|24965-27377|PILER-CR
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATTCTATTTAGATAAAGACATTCCGAAAGAACTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTACATTCTCTAAATGGTATGAACCAAACCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GAGATTGGGGGAAAGTAATATGGCAAGCAAGACATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTATGTGATCTACCGGTCTTCAATCGACTCTCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATTCCATGCCACCAAAGGACTGGCAAGAAGCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGGTATAGCAAACAAGCCATCGAAAGGTGGCTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTGTCTACTTCTGTAATTCCTACTGCATAA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACAAGTTGTGTAAGGAACGTGATATTGATTGTAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CTTCTCTCATATCCATACTTCAAATTGTCTGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATATCACAAAGATACATTGGAAAAATTAACGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAAGCCAATGGAACTTGCAGAACGGTTTGCAGA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTCTTTTAAATCCATTTTTCACTCTAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GGTATTGACTGGTATAAGAAAGCAATGGATGATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TAAGCTGCCATTTTCTGCTTCCATGCTTCGATTGC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTACGGTACTTCCTACTGTAATACCTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCTCATTTGTGTGCCTGCCAATCAGGAACACC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCTCCTTACGCTATTGCCGCCGTCTGGATTGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCAGTTGTCTTTTGAAAGAAAACTGCTGTGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCGGCATGGCAATTAAGCAGTCTGAGACTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAATTCCATGTTCTTCTTCCTTTCTCCGTCATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCCTTTCAGAATTTCAATGAATGCTTCATAGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACTTGATGCATAACCGACGATATTCTTATAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGTTATCAGAAATGCAATTACAGATAACAGAAATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATAAGAGCGCTTGAAGAAGCCATGCTAAAAATA
GTCGTCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCGAATGGGGAACTACAAAGCAACCACCACAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGCCAGGCTTCCGTTAATGCGCGCTTCCAGTTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTTGCGCACGAATACATATACATCCTTTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATGATACAGAAGAAGAAAGAGAGGAAAATGTCGG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTACAGCTATCAAAGCCAGTATCTTTGAAAATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTTCTCCCTTTGAAAGTCTTACAACTGGTAAAAGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GACAATCTCCGGTCCCGCTTCTGCCACGATCGCG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCAGTCCTTCGCCGTGTCGGTTACTCTGGTAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCACTCTGCACCGATGTAGTTCAGGACTTTCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCCTGCTGTTCCTTCCACTGTTCTTCGAAATCTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCATTACTCTTGACCGTTGTTGTGTTGGATGCTCCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AACTGACTGCTTTGCAGCATTTAAGACAAGTGCTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT

>NZ_QTWH01000024|1|1|24965-27445|CRISPRCasFinder
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATTCTATTTAGATAAAGACATTCCGAAAGAACTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTACATTCTCTAAATGGTATGAACCAAACCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GAGATTGGGGGAAAGTAATATGGCAAGCAAGACATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTATGTGATCTACCGGTCTTCAATCGACTCTCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATTCCATGCCACCAAAGGACTGGCAAGAAGCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGGTATAGCAAACAAGCCATCGAAAGGTGGCTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTGTCTACTTCTGTAATTCCTACTGCATAA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACAAGTTGTGTAAGGAACGTGATATTGATTGTAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CTTCTCTCATATCCATACTTCAAATTGTCTGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATATCACAAAGATACATTGGAAAAATTAACGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAAGCCAATGGAACTTGCAGAACGGTTTGCAGA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTCTTTTAAATCCATTTTTCACTCTAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GGTATTGACTGGTATAAGAAAGCAATGGATGATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TAAGCTGCCATTTTCTGCTTCCATGCTTCGATTGC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTACGGTACTTCCTACTGTAATACCTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCTCATTTGTGTGCCTGCCAATCAGGAACACC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCTCCTTACGCTATTGCCGCCGTCTGGATTGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCAGTTGTCTTTTGAAAGAAAACTGCTGTGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCGGCATGGCAATTAAGCAGTCTGAGACTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAATTCCATGTTCTTCTTCCTTTCTCCGTCATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCCTTTCAGAATTTCAATGAATGCTTCATAGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACTTGATGCATAACCGACGATATTCTTATAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGTTATCAGAAATGCAATTACAGATAACAGAAATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATAAGAGCGCTTGAAGAAGCCATGCTAAAAATA
GTCGTCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCGAATGGGGAACTACAAAGCAACCACCACAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGCCAGGCTTCCGTTAATGCGCGCTTCCAGTTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTTGCGCACGAATACATATACATCCTTTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATGATACAGAAGAAGAAAGAGAGGAAAATGTCGG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTACAGCTATCAAAGCCAGTATCTTTGAAAATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTTCTCCCTTTGAAAGTCTTACAACTGGTAAAAGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GACAATCTCCGGTCCCGCTTCTGCCACGATCGCG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCAGTCCTTCGCCGTGTCGGTTACTCTGGTAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCACTCTGCACCGATGTAGTTCAGGACTTTCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCCTGCTGTTCCTTCCACTGTTCTTCGAAATCTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCATTACTCTTGACCGTTGTTGTGTTGGATGCTCCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AACTGACTGCTTTGCAGCATTTAAGACAAGTGCTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CTTGAAGAGTACGGCGTTAATCATCGTTGTAGCAAT
ATGGTTCTTCTTGTGGGGAGGTGAATTGAAAT

>NZ_QTWH01000024|1|1|24965-27445|CRT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATTCTATTTAGATAAAGACATTCCGAAAGAACTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTACATTCTCTAAATGGTATGAACCAAACCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GAGATTGGGGGAAAGTAATATGGCAAGCAAGACATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTATGTGATCTACCGGTCTTCAATCGACTCTCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATTCCATGCCACCAAAGGACTGGCAAGAAGCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGGTATAGCAAACAAGCCATCGAAAGGTGGCTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTGTCTACTTCTGTAATTCCTACTGCATAA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACAAGTTGTGTAAGGAACGTGATATTGATTGTAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CTTCTCTCATATCCATACTTCAAATTGTCTGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATATCACAAAGATACATTGGAAAAATTAACGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAAGCCAATGGAACTTGCAGAACGGTTTGCAGA
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTCTTTTAAATCCATTTTTCACTCTAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GGTATTGACTGGTATAAGAAAGCAATGGATGATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TAAGCTGCCATTTTCTGCTTCCATGCTTCGATTGC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AATTGTTACGGTACTTCCTACTGTAATACCTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCTCATTTGTGTGCCTGCCAATCAGGAACACC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCTCCTTACGCTATTGCCGCCGTCTGGATTGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCAGTTGTCTTTTGAAAGAAAACTGCTGTGATT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCGGCATGGCAATTAAGCAGTCTGAGACTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AAAAATTCCATGTTCTTCTTCCTTTCTCCGTCATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCCCTTTCAGAATTTCAATGAATGCTTCATAGCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACTTGATGCATAACCGACGATATTCTTATAAAC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGTTATCAGAAATGCAATTACAGATAACAGAAATG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATAAGAGCGCTTGAAGAAGCCATGCTAAAAATA
GTCGTCCTCTTCGTGAGGATGTGAGTTGAAAT	GTCGAATGGGGAACTACAAAGCAACCACCACAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AGCCAGGCTTCCGTTAATGCGCGCTTCCAGTTTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATACTTGCGCACGAATACATATACATCCTTTTTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GATGATACAGAAGAAGAAAGAGAGGAAAATGTCGG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GTACAGCTATCAAAGCCAGTATCTTTGAAAATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	TTTCTCCCTTTGAAAGTCTTACAACTGGTAAAAGTT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GACAATCTCCGGTCCCGCTTCTGCCACGATCGCG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ACCAGTCCTTCGCCGTGTCGGTTACTCTGGTAAG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	ATCACTCTGCACCGATGTAGTTCAGGACTTTCT
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCCTGCTGTTCCTTCCACTGTTCTTCGAAATCTATC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	GCATTACTCTTGACCGTTGTTGTGTTGGATGCTCCC
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	AACTGACTGCTTTGCAGCATTTAAGACAAGTGCTG
GTCATCCTCTTCGTGAGGATGTGAGTTGAAAT	CTTGAAGAGTACGGCGTTAATCATCGTTGTAGCAAT
ATGGTTCTTCTTGTGGGGAGGTGAATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_QTWH01000024.1\|WP_117569987.1\|29808_32067_+\|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl\|CDD\|376320
NZ_QTWH01000024.1\|WP_117569986.1\|28730_29606_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_QTWH01000024.1\|WP_117569988.1\|32082_33588_+\|4-alpha-glucanotransferase	unknown	unknown	gnl\|CDD\|237738
NZ_QTWH01000024.1\|WP_117569989.1\|11833_12904_+\|carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183784
NZ_QTWH01000024.1\|WP_015529665.1\|12903_16107_+\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_QTWH01000024.1\|WP_117569981.1\|16790_19229_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_QTWH01000024.1\|WP_117569982.1\|19244_19988_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NZ_QTWH01000024.1\|WP_117569980.1\|10392_11628_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227604
NZ_QTWH01000024.1\|WP_117569983.1\|19984_21934_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_QTWH01000024.1\|WP_055161640.1\|24504_24795_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_QTWH01000024.1\|WP_117569984.1\|21952_22801_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_QTWH01000024.1\|WP_117540735.1\|22802_23468_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|187768
NZ_QTWH01000024.1\|WP_117540737.1\|23464_24496_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_QTWH01000024.1\|WP_117569985.1\|27897_28713_+\|PHP-domain-containing-protein	unknown	unknown	gnl\|CDD\|213987

Protein	Function_ID	Function_description	E-value
NZ_QTWH01000024.1\|WP_117569987.1\|29808_32067_+\|glycogen/starch/alpha-glucan-phosphorylase	gnl\|CDD\|376320	pfam00343, Phosphorylase, Carbohydrate phosphorylase. The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin.	0
NZ_QTWH01000024.1\|WP_117569986.1\|28730_29606_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.02935e-32
NZ_QTWH01000024.1\|WP_117569988.1\|32082_33588_+\|4-alpha-glucanotransferase	gnl\|CDD\|237738	PRK14508, PRK14508, 4-alpha-glucanotransferase; Provisional.	0
NZ_QTWH01000024.1\|WP_117569989.1\|11833_12904_+\|carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|183784	PRK12838, PRK12838, carbamoyl phosphate synthase small subunit; Reviewed.	0
NZ_QTWH01000024.1\|WP_015529665.1\|12903_16107_+\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_QTWH01000024.1\|WP_117569981.1\|16790_19229_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.76927e-46
NZ_QTWH01000024.1\|WP_117569982.1\|19244_19988_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.1279e-85
NZ_QTWH01000024.1\|WP_117569980.1\|10392_11628_+\|hypothetical-protein	gnl\|CDD\|227604	COG5279, CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain [Cell division and chromosome partitioning].	1.38752e-22
NZ_QTWH01000024.1\|WP_117569983.1\|19984_21934_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	3.31188e-147
NZ_QTWH01000024.1\|WP_055161640.1\|24504_24795_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.99106e-29
NZ_QTWH01000024.1\|WP_117569984.1\|21952_22801_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.48281e-107
NZ_QTWH01000024.1\|WP_117540735.1\|22802_23468_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	6.64642e-28
NZ_QTWH01000024.1\|WP_117540737.1\|23464_24496_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_QTWH01000024.1\|WP_117569985.1\|27897_28713_+\|PHP-domain-containing-protein	gnl\|CDD\|213987	cd07432, PHP_HisPPase, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to produce histidinol. HisPPase can be classified into two types: the bifunctional HisPPase found in proteobacteria that belongs to the DDDD superfamily and the monofunctional Bacillus subtilis type that is a member of the PHP family. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	3.2385e-20

>NZ_QTWH01000024.1|WP_055161640.1|24504_24795_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVNTQTAAGRKRLRKVAKECTNYGQRVQNSVFECQMDATKCRQVKNILENIIDKEVDSLRFYYLGEKYKNKVEHIGAKPGFDVKDTLIF
>NZ_QTWH01000024.1|WP_117540737.1|23464_24496_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKRLLNTLYVTSGNKYLSLDGENVVVLEDQKEIGRIPLHNLQAIITFGYTGASPALMGVCAQRNIDLSFMSGNGRFLARVTGEVKGNVTLRKQQYRISDNRDESVHIARNFILGKVYNSRWILERAARDYALRLDVETIKKKSVFLAQSMGKIRECENAEELLGLEGEAASVYFSVFDDLILQQKDNFYFHGRNKRPPLDNVNAMLSFGYSLLAGMCGGALEAVGLDSYVGFFHTDRPGRMSLALDLMEEFRSVMVDRFVLTLINKKIMKEKYFIKKENGAVIMTDEGRKAFLSAWQSKKQETIKHPFLDEKIEWGMAPYVQSMLLARYLRGDLDEYPPFFWK
>NZ_QTWH01000024.1|WP_117540735.1|22802_23468_+|CRISPR-associated-protein-Cas4
MYKEEDFLQLSGIQHFEFCRRQWALAYIELQWQENVRTVEGKILHENAHDASIKEKRGDLIVVRAMPIHSREMGVSGECDVVEFHKAKDGISLSGKEGFYKVVPIEYKRGKPKTDDSDILQVTAQALCLEEMLCCTIPYGYIYYGETKHRAKVEFTDEIRDKVRKIFAEMHKYYAQCYTPKVKISKKCNACSLKDICLPVLNKKKSVSGYIDKIISEEEKG
>NZ_QTWH01000024.1|WP_117569984.1|21952_22801_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSELKGKIDFTLFISANNANPNGDPLNGNRPRINMDGFGEISDVCIKRKIRNRFQDLGQKIFVQSDDRTDDAYTSLKDRADSCEELKAEMGNKKNANRDACAAIACKEWLDVRAFGQVFAFKGIPVSFGVRGPVSIHQAVSLSPIDIISMQITKSVNSESGKESKASDTMGTKHRVGFAVYKVMGSVNVQLAEKTGFNQEDAEVLKEALKTLFENDASSARPEGSMEVCKMYWWQHDEKTPAVSSGKIQRGFTIEAKKEHPREFEDYEISWDVEGCKQPEEF
>NZ_QTWH01000024.1|WP_117569983.1|19984_21934_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWINELIDLYEKNSDKIGVIEYRGDIPYVLLPTFHTTVTAQITVTIDQDGNFVRAEQVDQNDKLTIIPVTEKSGSRTAGKEPHPLCDNLRYLAGDYKKYYKDDGVCSKLYISQLEKWVESDYCHEKVRAVYEYLKKSTLIQDLVAYKIIKLNEENQIDEKENIQGIPQPKAFVRFIIRSFDEKIYQETPDECWKDRTLQECYIEYVRSQEKEKGICYLTGNMESISYLHSKKIRNEGDGAKLISANDSQNFTYRGRFTSKEEAFAVGNETSQKAHNALKWIIRKQGTFFDTMTIVTWESNQLSMPKWERDTEAIVSEYEREHVGNAEDDWEDDWSTGEIVSDGNPITADKFYKALRGYGKKIDNTSNMILLAFDAATPGRLALIENQELNSVRYLKNIEKWHNDCNWIHTKWKDGERIQFAGMVGVKDIADILYGIENKGTVSIVDANGKKLYAQVAQRLLPCIWNGTRVPYDYVMLAVSKASNPLVYKEQRNWERVLTLACSFVKKDKKDRYKEEWNVALDKKETDRNYLYGRLLAVADRIEYLTYDEKDNGRVTNAKRYMSTFSQRPYETWKVIEENIRPYLNKLDIAKRTFYENLLHEIDELFDKSTFTDNSRLEGLYLLGFHNQAYDLKLKKEKSEEKEESSEE
>NZ_QTWH01000024.1|WP_117569982.1|19244_19988_+|type-I-C-CRISPR-associated-protein-Cas5
MKRYRNTIEFEVYGTHALFSDPVMRVGGEKTSYHIPTYEALKGITESIYWKPTIIWIIDAVRVMNPIQTETKGIRPIAYNGGNELAYYTYLKDVRYQVRAHFEMNLNHTELKQDRNENKHHNIAKRMVKRGGRRDIFLGTRECQAFVEPCVFGEGESYYDTMPGEVGYGFMYHGITYAEEAILDEDKDQMTVRFWRPVMKKGGIIEFTRPEDCTEKRHIRPMERKVFGKEENNFVGLEEFTDEEVED
>NZ_QTWH01000024.1|WP_117569981.1|16790_19229_+|CRISPR-associated-helicase-Cas3'
MENKIEIKRDLAHVDYESGRYQTMKEHSENVANYVAETCSLSELKILVSLIGVFHDVGKLGRENQEDFERILQYGDDTHKHGLDHSTAGGRLIRELLKEKSVSEFISTVIYFHHGMGDCINLDNGQSLQQQRDEKQIDYDWIKKEFFQIYDKEMLEEYCKKAIQTYKEMEGKINIFHKESEISKRKCENRYFFMGMYLRMVLSLLIDGDWTDTACFFQDVPLSKRISLEETQKIWNECIEKFEQYMSKEIHNNPSNGNVLNTFRQEISDLCRQAADKEENLYRLTVPTGAGKTLSSLRFALYHAKKMKKQHIIYIAPFNSILIQNAEEIRKAIGKADVVLEHHCNVVCEEGEEDQYRKLTETWDSPIIVTTAVQILNTLFSAQKSCIRRMHTLCNSIIIFDEVQAIPVKCMELFNLAVNFLTQFCGTTVVLCSATQPTLAPIKENNICECIEMAGRPEKYANAFKRTDIKDATELYPGGMEIEDLSEFVKEKTEQYQSTLVILNTTACAMNTFQQLKAICPQEYELFHLSNNMCPQHKLDTLKSIKQILNEQSKKIICVSTQVVEAGVNFSFGCVVRSKAGLDNIIQAAGRCNRHKELGRMGTVFIVQMSEKAEKLSHLQEIRNAQAALQKVLEDYKNNSLKFRDTLDSEEAIKAYYLNYYSQLRTNETKFLIDKQTTTIIELLGENKVGQLQYIRRNGEKVKTKLPQAFLTAGEAFEVISNDYKVSVVVPYNDEARELLDKLSQDYLEIEEQKKILKKLQRYTVGISEKRKEKLGNAIYEICNGEILVLCDGYYDKEVGVVDEPNMELQML
>NZ_QTWH01000024.1|WP_015529665.1|12903_16107_+|carbamoyl-phosphate-synthase-large-subunit
MPRDNSIKKVLVIGSGPIVIGQAAEFDYAGTQACRSLKEEGIEVVLLNSNPATIMTDKDIADRVYIEPLTIEVVEQLIKKEKPDSVLPTLGGQAGLNLAMELEEAGFLKENNVRLIGTTSETIKKAEDRLEFKATMEKIGEPVAASLVVENVEDGLAFANKIGYPVVLRPAYTLGGSGGGIAHDSQQLVEILENGLRLSRVGQVLVERCIAGWKEIEYEVMRDGAGNCITVCNMENIDPVGVHTGDSIVVAPSQTLGDKEYQMLRTSALNIISELNITGGCNVQYALHPETFEYCVIEVNPRVSRSSALASKATGYPIAKVAAKIALGYNLDEIKNAITQKTYASFEPMLDYVVVKIPRLPFDKFISAKRTLTTQMKATGEVMSICNNFEGALMKAIRSLEQHVDSLMSYDFTDLTDDELIDQLKKVDDMRMWRIAEACRRGISYDLIHEITKVDEWFIDKFAIITEMETALKTQELTPELLAEAKRIEFPDNVIAQLTGKTEQEIHDMRHANGIVAAYKIVDTCAAEFAAETPYYYSVYGSENEVEQTKDKKKVLVLGSGPIRIGQGIEFDFCSVHCTWAFAKDGYETIIVNNNPETVSTDFDIADKLYFEPLTPEDVESIVDIEKPDGAVVQFGGQTAIKLTEALMKMGVPILGTSAENVDKAEDRELFDEILEECEIPRPTGGTVFTAEEAKEVANRLGYPVLVRPSYVLGGQGMQIAINDNDIDEFIGIINRIAQDHPILVDKYLQGKEIEVDAVCDGTDILIPGIMEHIERAGIHSGDSISVYPAQSLTEGAKAKIAEYTRRLAKSLHVIGMINIQFIVCGEDDVYVIEVNPRSSRTVPYISKVTGIPIVPLATQVITGKKIKDLGYTPGLQPEADYVAVKMPVFSFEKIRGADISLGPEMKSTGECLGIAKTFDEALYKAFIGAGIKLPKHKNMIMTVRDEDHADAVEIGRRFEKIGYHIFATSGTARALNEAGVKATPVRKIEQESPNLLDLILGHKIDLVIDIPAQGAEHSRDGFVIRRNAIETGVNVLTAIDTAYALITSLENTDIKKLSLIDIAKVQ
>NZ_QTWH01000024.1|WP_117569989.1|11833_12904_+|carbamoyl-phosphate-synthase-small-subunit
MKAFLILEDGTVFTGTSIGSTRDMISEIVFNTSMTGYLEVLTDPSYAGQAVVMTYPLIGNYGITPDMESLKAWPDGYIVRELSRMPSNFRCEGTIQDFLKKYDIPGIAGVDTRALTKILREKGTMNGMITTNENYDLEEVISKLKNYKVEGVVSKVTCEEKYVLEGTGKKVALLDLGAKKNIAKSLNDRGCEVTVYPADTTAEEIIASNPDGIMLSNGPGDPAECTSIIKEIKKLYETDIPIFAICLGHQLMALATGGTTYKLKYGHRGGNHPVKDLQTGRVYISSQNHGYVVDEDKIDPNVAVPAFKNVNDGTNEGLAYVGKNIFTVQFHPEACPGPQDSGYLFDRFLEMMGGEK
>NZ_QTWH01000024.1|WP_117569980.1|10392_11628_+|hypothetical-protein
MERDRRRRKKRRRNRKTRRKGFVFLVLLLVVIGAAGVLKMIKATPGLFCESGNILLSDSGQKIEFPELNVSEEDVADGFYYQQLSEQEKQVYREILQGVRSMDETILLHAGENDEAGKIYEYLMYDRSELFWCDGSSKMTVYKDYTEFHPSYICTQDQRESRREQIENAAQEVLAGAQGCETEYEKIKYIFKYLVDTVDYDQNALDNQNIYSSLVGKRSVCAGYSRAAQYLLKQMGIECIYVVGTVKEQGAHAWNIVKCDDKYYQMDVTFGDPIFQENETGETLPHDLVNYEYLCCTDEEIFTDHQQDDFVPYPVCDSNDLEYYRINGLYYETFDENEIYEKMKAGIEQGQEMFAIRFSENAVYEVAKEKIIDNLIPQAAQFLVDFRQLEEVKYTYAVDDRKRIIMIFWYS
>NZ_QTWH01000024.1|WP_117569985.1|27897_28713_+|PHP-domain-containing-protein
MKIDMHCHVKEGSIDSRVGIEEYITILKERGFQGMVITDHDTYNGYRYWKKNLKGKKHTDFVVLKGIEYDTRDAGHILVIMPEGVKMRLLEMRGMPLALLIDLVHRNGGVLGPAHPCGEKYMSFTHARRYYLSPEIVKRFDFIETFNCCEPKDSNAGALKLAEKYGKVMTGGSDSHKTDCVGRAYTILPEPVKTETELISLIHKKTAFKTGGVYYNKTTKEKIGKVNKLLVYSFWVYNKSGELMKRRGRNKKMEEEHPFDPIDPIELYYHS
>NZ_QTWH01000024.1|WP_117569986.1|28730_29606_-|AraC-family-transcriptional-regulator
MNINEYQNYHETKAHTSAEFPYNTYLCSIPLDFPGVPLHWHDELELVVIKRGQGFVSVDFDKHLVHSGDIIMIRPGCLHAIEQDDTFKMEYENIIFKPSLLSSGANDLCMLQYIMPLLDGSLSVEYFLTPALESFEALSNCIRQIDLVCADQTPGWQLAVKSSLFNFFFLLISESQKKTVSTSSNSKSLEKMKTVLKYVENHYTEKLTIDDMAELTYYSKSHFMKFFKAHMGIGFTEYLNDYRLTMAARLLKSSDDSILMIADASGFDNLSYFNRIFKRKYGISPGAYRKA
>NZ_QTWH01000024.1|WP_117569987.1|29808_32067_+|glycogen/starch/alpha-glucan-phosphorylase
MQMNIQETLQQKLGKEIAQASNEEIYGALLSMVQEMAGEKERTDSKKKLYYISAEFLIGKLLSNNMINLGIFNEIKDVLAQNGKNIAEIEEVEPEPSLGNGGLGRLAACFLDSIATLGLAGDGVGLNYHLGLFKQEFKNNLQRETPNPWIEAKSWLKKTDVVYPVSFKGLNVNARMYDIEVTGYNNKTNKLHLFDIDSVDETIVEDGITFNKEDIEKNLTLFLYPDDSDENGRLLRIYQQYFMVSAGAQLILDECTAKGCNLHDLADYAVIQINDTHPTMVIPELIRILVERGLDMDEAIEVVSKTCAYTNHTILAEALEKWPVYYLKKVVPQLMPIIEVLDDKVRRKYEDESVSIIDRNDTVHMAHIDIHYGFSVNGVASLHTEILKETELNNFYKIYPEKFNNKTNGITFRRWLLHCNPTLTELLDELIGEGYKKDAAELEKLLAFKDDDKVLDRLVEIKHANKEALCKYLEETQGVKVSPDTIFDIQIKRLHEYKRQQLNALYIIDKYLEIKAGKIPAAPVTAIFGAKAAPAYVIAKDIIHLILCLQEIINNDPEVSPYLKVVMVENYNVTKAEKLIPACDISEQISLASKEASGTGNMKFMLNGAVTLGTEDGANVEIHELVGNDNIFVFGASSDEVIEHYAKADYVARDFYEKNPAIKAAIDFITSEEVLKVGEKENLERLQHEIISKDWFMTLLDFDSYKEKKEEALRAYADQKTWAKKALVNIAKAGYFSSDRTIEEYNRDIWHL
>NZ_QTWH01000024.1|WP_117569988.1|32082_33588_+|4-alpha-glucanotransferase
MKRASGVLLPVFSLPSKYGIGCFSKEAYKFIDQLKEAGQSYWQILPLGPTGYGDSPYQSFSTYAGNPYFIDLKTLIKEGLLTKKECKTYDFGEQADSIDYEKIYNSRFKVLKKAFERFEKDEAYDNFVKENAYWLDDYSLYMAIKDSKGGISWNEWEEALKNREEAALENAREELAEEIDFYKFQQYEFDKQWSQLHAYANEQGIQIVGDIPIYVAFDGADTWASPELFQFDEENNPVAVAGCPPDDFSATGQLWGNPLYNWEYHKKTGYDWWIKRIRHCLKLYDVVRIDHFRGFDEYYSIPYGNETAVDGTWMPGPGMDLFHTIEERLGKLNIIAEDLGFLTESVLQMLSDSGFPGMKVVQFAFDPNGGSTYLPHNYPENSVVYTGTHDNDTTRGWYHSTDKATRDFAKEYMNAQRLDEDDLAWDFIRLAMSSKANLCVTPMQDLLNLDGKARINVPSTLGGNWTWRMEKGQFDEETVKRLKRMTWLYERLPREVEKKIK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_QTWH01000024_1	1.10\|25590\|34\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25590-25623	34	EU246945	Lactobacillus phage Lrm1, complete sequence	32625-32658	5	0.853
NZ_QTWH01000024_1	1.10\|25590\|34\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25590-25623	34	NC_011104	Lactobacillus phage Lrm1, complete genome	32625-32658	5	0.853
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	MH791397	UNVERIFIED: Enterococcus phage EfsSzw-1, complete genome	136540-136571	7	0.781
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	NZ_CP038864	Campylobacter jejuni strain SCJK2 plasmid p2, complete sequence	34014-34045	7	0.781
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	NZ_CP011157	Bacillus cereus strain HN001 plasmid pRML02, complete sequence	25587-25618	8	0.75
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	MG592499	Vibrio phage 1.124.O._10N.286.49.B1, partial genome	45889-45920	8	0.75
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	MG592531	Vibrio phage 1.164.O._10N.261.51.A7, partial genome	46464-46495	8	0.75
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	MT648818	Acinetobacter phage FG02, partial genome	42005-42039	8	0.771
NZ_QTWH01000024_1	1.2\|25063\|33\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25063-25095	33	NC_012226	Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence	2922-2954	9	0.727
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	NZ_CP053834	Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence	72997-73028	9	0.719
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	MN694172	Marine virus AFVG_250M818, complete genome	43078-43109	9	0.719
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	MN508623	UNVERIFIED: Enterobacter phage EC-F1, complete genome	153467-153501	9	0.743
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	MH823906	Citrobacter phage Maroon, complete genome	155616-155650	9	0.743
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	LC589952	Enterobacter phage vB_EkoM5VN DNA, complete genome	25711-25745	9	0.743
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	MT341500	Enterobacter phage EBPL, complete genome	158463-158497	9	0.743
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	NC_048645	Cronobacter phage vB_CsaM_leB, complete genome	154389-154423	9	0.743
NZ_QTWH01000024_1	1.20\|26249\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26249-26283	35	MK448739	Streptococcus phage Javan363, complete genome	10107-10141	9	0.743
NZ_QTWH01000024_1	1.20\|26249\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26249-26283	35	MK448918	Streptococcus phage Javan366, complete genome	11540-11574	9	0.743
NZ_QTWH01000024_1	1.2\|25063\|33\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25063-25095	33	NZ_CP019601	Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence	34973-35005	10	0.697
NZ_QTWH01000024_1	1.2\|25063\|33\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25063-25095	33	NZ_CP016085	Brachyspira hyodysenteriae ATCC 27164 strain B-78 plasmid pBhyoB78, complete sequence	21002-21034	10	0.697
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	NC_048646	Cronobacter phage vB_CsaM_leE, complete genome	158470-158504	10	0.714
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	MN508621	UNVERIFIED: Enterobacter phage EC-W1, complete genome	171451-171485	10	0.714
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	JN882287	Cronobacter phage vB_CsaM_GAP161, complete genome	154562-154596	10	0.714
NZ_QTWH01000024_1	1.14\|25853\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25853-25887	35	KT381880	Citrobacter phage Margaery, complete genome	155196-155230	10	0.714
NZ_QTWH01000024_1	1.20\|26249\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26249-26283	35	MK448914	Streptococcus phage Javan348, complete genome	12127-12161	10	0.714
NZ_QTWH01000024_1	1.28\|26778\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26778-26812	35	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	11667-11701	10	0.714
NZ_QTWH01000024_1	1.28\|26778\|35\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26778-26812	35	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	47813-47847	10	0.714
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	AJ972879	Yersinia phage phiR1-37 complete genome	257181-257212	11	0.656
NZ_QTWH01000024_1	1.12\|25723\|32\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25723-25754	32	NC_016163	Yersinia phage phiR1-37, complete genome	257181-257212	11	0.656
NZ_QTWH01000024_1	1.17\|26052\|34\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	26052-26085	34	MF959998	Marinobacter phage PS6, complete genome	19049-19082	11	0.676
NZ_QTWH01000024_1	1.6\|25326\|34\|NZ_QTWH01000024\|PILER-CR,CRISPRCasFinder,CRT	25326-25359	34	NZ_CP046125	Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence	14418-14451	12	0.647

1. spacer 1.10|25590|34|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to EU246945 (Lactobacillus phage Lrm1, complete sequence) position: , mismatch: 5, identity: 0.853

atatcacaa--agatacattggaaaaattaacgatt	CRISPR spacer
--atcataatcagatacattggcaaaattaacggtt	Protospacer
  ****.**  *********** **********.**

2. spacer 1.10|25590|34|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NC_011104 (Lactobacillus phage Lrm1, complete genome) position: , mismatch: 5, identity: 0.853

atatcacaa--agatacattggaaaaattaacgatt	CRISPR spacer
--atcataatcagatacattggcaaaattaacggtt	Protospacer
  ****.**  *********** **********.**

3. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MH791397 (UNVERIFIED: Enterococcus phage EfsSzw-1, complete genome) position: , mismatch: 7, identity: 0.781

aattgttcttttaaatccatttttcactctac	CRISPR spacer
taagcttcttttaaatccattattctctctcc	Protospacer
 *   **************** *** **** *

4. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038864 (Campylobacter jejuni strain SCJK2 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

aattgttcttttaaatccatttttcactctac	CRISPR spacer
atatgtttttttaaatccattttgcaccaaac	Protospacer
*  ****.*************** ***.  **

5. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011157 (Bacillus cereus strain HN001 plasmid pRML02, complete sequence) position: , mismatch: 8, identity: 0.75

aattgttcttttaaatccatttttcactctac	CRISPR spacer
aattgttcttgtaaatacattttaaaatattt	Protospacer
********** ***** ******  * * * .

6. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MG592499 (Vibrio phage 1.124.O._10N.286.49.B1, partial genome) position: , mismatch: 8, identity: 0.75

aattgttcttttaaatccatttttcactctac	CRISPR spacer
agttgttgttttaaattcatttttccattttt	Protospacer
*.***** ********.********  *.* .

7. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MG592531 (Vibrio phage 1.164.O._10N.261.51.A7, partial genome) position: , mismatch: 8, identity: 0.75

aattgttcttttaaatccatttttcactctac	CRISPR spacer
agttgttgttttaaattcatttttccattttt	Protospacer
*.***** ********.********  *.* .

8. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MT648818 (Acinetobacter phage FG02, partial genome) position: , mismatch: 8, identity: 0.771

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
tccgcacctgttttcttcttccatgcttcggttgc	Protospacer
*  **  *..****** *************.****

9. spacer 1.2|25063|33|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NC_012226 (Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence) position: , mismatch: 9, identity: 0.727

aattacattctctaaatggtatgaaccaaaccc	CRISPR spacer
ctcttctttttctaaatggtatgaaccatacta	Protospacer
  .* * **.****************** **.

10. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053834 (Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence) position: , mismatch: 9, identity: 0.719

aattgttcttttaaatccatttttcactctac	CRISPR spacer
aaatgttcttttaaattcattttataaatacc	Protospacer
** *************.****** .*  .  *

11. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MN694172 (Marine virus AFVG_250M818, complete genome) position: , mismatch: 9, identity: 0.719

aattgttcttttaaatccatttttcactctac	CRISPR spacer
tgttgttcttttatattcatttttcctcctct	Protospacer
 .*********** **.******** ..** .

12. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MN508623 (UNVERIFIED: Enterobacter phage EC-F1, complete genome) position: , mismatch: 9, identity: 0.743

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccatatcctgttttcttcttccatgcttcggttgc	Protospacer
. *  * *..****** *************.****

13. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MH823906 (Citrobacter phage Maroon, complete genome) position: , mismatch: 9, identity: 0.743

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccatatcctgttttcttcttccatgcttcggttgc	Protospacer
. *  * *..****** *************.****

14. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to LC589952 (Enterobacter phage vB_EkoM5VN DNA, complete genome) position: , mismatch: 9, identity: 0.743

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccatatcctgttttcttcttccatgcttcggttgc	Protospacer
. *  * *..****** *************.****

15. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MT341500 (Enterobacter phage EBPL, complete genome) position: , mismatch: 9, identity: 0.743

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccatatcctgttttcttcttccatgcttcggttgc	Protospacer
. *  * *..****** *************.****

16. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NC_048645 (Cronobacter phage vB_CsaM_leB, complete genome) position: , mismatch: 9, identity: 0.743

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccatatcctgttttcttcttccatgcttcggttgc	Protospacer
. *  * *..****** *************.****

17. spacer 1.20|26249|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MK448739 (Streptococcus phage Javan363, complete genome) position: , mismatch: 9, identity: 0.743

aaaaattccatgttcttcttcctttctccgtcatg	CRISPR spacer
acaaattccatgttctacctcctttctgcaaaaca	Protospacer
* ************** *.******** *.  *..

18. spacer 1.20|26249|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MK448918 (Streptococcus phage Javan366, complete genome) position: , mismatch: 9, identity: 0.743

aaaaattccatgttcttcttcctttctccgtcatg	CRISPR spacer
acaaattccatgttctacctcctttctgcaaaaca	Protospacer
* ************** *.******** *.  *..

19. spacer 1.2|25063|33|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019601 (Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence) position: , mismatch: 10, identity: 0.697

aattacattctctaaatggtatgaaccaaaccc	CRISPR spacer
ctcttttttttctaaatggtatgaaccatacta	Protospacer
  .* . **.****************** **.

20. spacer 1.2|25063|33|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016085 (Brachyspira hyodysenteriae ATCC 27164 strain B-78 plasmid pBhyoB78, complete sequence) position: , mismatch: 10, identity: 0.697

aattacattctctaaatggtatgaaccaaaccc	CRISPR spacer
ctcttttttttctaaatggtatgaaccatacta	Protospacer
  .* . **.****************** **.

21. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NC_048646 (Cronobacter phage vB_CsaM_leE, complete genome) position: , mismatch: 10, identity: 0.714

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccaaaaccagttttcttcttccatgcttcggttgc	Protospacer
. *.   * .****** *************.****

22. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MN508621 (UNVERIFIED: Enterobacter phage EC-W1, complete genome) position: , mismatch: 10, identity: 0.714

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccataccctgttttcttcttccatgcttcggttgc	Protospacer
. *  . *..****** *************.****

23. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to JN882287 (Cronobacter phage vB_CsaM_GAP161, complete genome) position: , mismatch: 10, identity: 0.714

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccaaaaccagttttcttcttccatgcttcggttgc	Protospacer
. *.   * .****** *************.****

24. spacer 1.14|25853|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to KT381880 (Citrobacter phage Margaery, complete genome) position: , mismatch: 10, identity: 0.714

taagctgccattttctgcttccatgcttcgattgc	CRISPR spacer
ccaaaacctgttttcttcttccatgcttcggttgc	Protospacer
. *.   *..****** *************.****

25. spacer 1.20|26249|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MK448914 (Streptococcus phage Javan348, complete genome) position: , mismatch: 10, identity: 0.714

aaaaattccatgttcttcttcctttctccgtcatg	CRISPR spacer
acaaattccatgttctacctcctttctataaaaca	Protospacer
* ************** *.******** ..  *..

26. spacer 1.28|26778|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 10, identity: 0.714

gatgatacagaagaagaaagagaggaaaatgtcgg	CRISPR spacer
atagatacagaagaagaaaaagaagaaattttatt	Protospacer
.  ****************.***.**** * *

27. spacer 1.28|26778|35|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 10, identity: 0.714

gatgatacagaagaagaaagagaggaaaatgtcgg	CRISPR spacer
atagatacagaagaagaaaaagaagaaattttatt	Protospacer
.  ****************.***.**** * *

28. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to AJ972879 (Yersinia phage phiR1-37 complete genome) position: , mismatch: 11, identity: 0.656

aattgttcttttaaatccatttttcactctac	CRISPR spacer
ttcatctcttttaaatccattctttactccca	Protospacer
  .  .***************.**.****.

29. spacer 1.12|25723|32|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NC_016163 (Yersinia phage phiR1-37, complete genome) position: , mismatch: 11, identity: 0.656

aattgttcttttaaatccatttttcactctac	CRISPR spacer
ttcatctcttttaaatccattctttactccca	Protospacer
  .  .***************.**.****.

30. spacer 1.17|26052|34|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to MF959998 (Marinobacter phage PS6, complete genome) position: , mismatch: 11, identity: 0.676

acctccttacgctattgccgccgtctggattgtt	CRISPR spacer
acttccttccgctattgccgccgtactgggcaca	Protospacer
**.***** *************** . *. ...

31. spacer 1.6|25326|34|NZ_QTWH01000024|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046125 (Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence) position: , mismatch: 12, identity: 0.647

aggtatagcaaacaagccatcgaaaggtggcttt	CRISPR spacer
taataaagcaaacaagccaacgaaaggcattaaa	Protospacer
 ..** ************* *******.. .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

10. NZ_QTWH01000014

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

112312 : 122823

uncultured_Caudovirales_phage(37.5%)

integrase

attL 120130:120141|attR 122947:122958

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117569523.1\|112312_114160_-	DUF927 domain-containing protein	A0A2K9V2Z1	Faecalibacterium_phage	6.2e-46	33.3
WP_117569524.1\|114143_114656_-	DNA primase	NA	NA	NA	NA
WP_117569535.1\|114652_115153_-	ERCC4 domain-containing protein	NA	NA	NA	NA
WP_117569536.1\|115163_115595_-	single-stranded DNA-binding protein	A0A2H4J8K2	uncultured_Caudovirales_phage	9.4e-30	57.0
WP_117569525.1\|115590_116346_-	ERF family protein	A0A1W6JP21	Morganella_phage	1.3e-26	47.3
WP_117569526.1\|116345_117281_-	DUF1351 domain-containing protein	A0A2H4J4V1	uncultured_Caudovirales_phage	9.1e-38	46.8
WP_117569527.1\|117829_118078_-	hypothetical protein	NA	NA	NA	NA
WP_054751657.1\|118092_118332_-	hypothetical protein	NA	NA	NA	NA
WP_054751655.1\|118400_118652_-	hypothetical protein	NA	NA	NA	NA
WP_054751653.1\|118664_119399_-	ORF6C domain-containing protein	A0A288WG93	Bacillus_phage	2.9e-47	43.3
WP_117569528.1\|119426_119681_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_117569529.1\|119778_120267_+	helix-turn-helix transcriptional regulator	A0A0A7RTR3	Clostridium_phage	3.7e-06	31.1
120130:120141	attL	NA	NA	NA	NA
WP_054751645.1\|120328_120790_+	hypothetical protein	A0A0A7RTX7	Clostridium_phage	1.2e-38	52.7
WP_054751643.1\|120874_121504_+	hypothetical protein	NA	NA	NA	NA
WP_117569530.1\|121710_122823_+\|integrase	site-specific integrase	A0A2H4J8J9	uncultured_Caudovirales_phage	7.5e-63	37.9
122947:122958	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

11. NZ_QTWH01000035

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1709 : 7942

Streptococcus_phage(33.33%)

integrase

attL 277:291|attR 6084:6098

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
277:291	attL	NA	NA	NA	NA
WP_117825252.1\|1709_2939_-\|integrase	site-specific integrase	H7BUX8	unidentified_phage	4.8e-95	43.4
WP_023920548.1\|2948_3230_-	helix-turn-helix domain-containing protein	A0A1S5SF07	Streptococcus_phage	2.3e-05	48.2
WP_002594705.1\|3195_3423_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002594704.1\|3521_3728_-	excisionase family DNA-binding protein	A0A1S5SF07	Streptococcus_phage	6.5e-05	35.5
WP_117825250.1\|3714_4281_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5RCS0	Lactobacillus_phage	1.1e-09	37.3
WP_055291085.1\|4386_4974_-	hypothetical protein	NA	NA	NA	NA
WP_002594701.1\|5285_5534_-	hypothetical protein	NA	NA	NA	NA
WP_055196061.1\|5530_6256_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
6084:6098	attR	NA	NA	NA	NA
WP_055291083.1\|6386_6986_-	repressor LexA	A0A1W6JNS2	Morganella_phage	4.1e-07	32.5
WP_055215141.1\|7174_7942_-	helix-turn-helix domain-containing protein	A0A2I7SC14	Paenibacillus_phage	8.3e-05	35.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage