CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_FERW01000021	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000060	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000005	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	1	2
NZ_FERW01000011	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000016	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	1	0	0	0
NZ_FERW01000004	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	2	0
NZ_FERW01000040	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000014	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	WYL	0	0	0	0
NZ_FERW01000042	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000056	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000018	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000039	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000053	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000001	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_FERW01000023	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000003	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000067	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000030	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000036	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
NZ_FERW01000009	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000062	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000010	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	0	0	0	0
NZ_FERW01000072	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000063	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000054	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000013	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
NZ_FERW01000045	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000047	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000006	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000020	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000027	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000050	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000066	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	1	0	0	0
NZ_FERW01000061	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000031	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	2 crisprs	NA	2	0	0	0
NZ_FERW01000007	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	cas3	1	0	0	0
NZ_FERW01000064	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000017	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	DEDDh	0	0	0	0
NZ_FERW01000043	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000034	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000002	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000048	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000070	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000019	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000015	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000069	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000065	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000022	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000012	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	DinG	0	0	0	0
NZ_FERW01000052	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000041	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000068	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000025	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	0	0	0	0
NZ_FERW01000008	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	1	1	0	0
NZ_FERW01000038	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000028	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	1 crisprs	NA	1	0	0	0
NZ_FERW01000058	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000033	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	c2c4_V-U1	0	0	0	0
NZ_FERW01000024	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	1	0
NZ_FERW01000059	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000055	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000037	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000026	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000032	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000049	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000029	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000046	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000057	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000071	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000035	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000044	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0
NZ_FERW01000051	Neisseria meningitidis strain 2842STDY5881035, whole genome shotgun sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000031_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000031_1

1090-1192

Orphan

I-E

Consensus_repeat	Method
GATTCCCGCCTGCGCGGGAATGACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000031_1

>merge|NZ_FERW01000031|1|1090-1192|CRISPRCasFinder
CATTCCCGCGCAGGCGGGAATCCAGACCCCCAACGCGGCAGGAATCTATCGGAAATAACCGAAACCGGACGAACCTAGATTCCCGCTTTCGCGGGAATGACGG

>NZ_FERW01000031|1|1|1090-1192|CRISPRCasFinder
CATTCCCGCGCAGGCGGGAATCCAG	ACCCCCAACGCGGCAGGAATCTATCGGAAATAACCGAAACCGGACGAACCTA
GATTCCCGCTTTCGCGGGAATGACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000031.1\|WP_002219349.1\|11307_11913_+\|Smr/MutS-family-protein	unknown	unknown	gnl\|CDD\|225396
NZ_FERW01000031.1\|WP_002219343.1\|2685_3330_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|182775
NZ_FERW01000031.1\|WP_002219347.1\|7770_8907_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_FERW01000031.1\|WP_002232360.1\|9541_10597_+\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224529
NZ_FERW01000031.1\|WP_042743482.1\|1704_2523_+\|adhesin-Opc	unknown	unknown	gnl\|CDD\|369279
NZ_FERW01000031.1\|WP_002213667.1\|5279_5645_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000031.1\|WP_002237893.1\|10593_10791_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000031.1\|WP_042743485.1\|5755_7231_+\|anthranilate-synthase-component-I	unknown	unknown	gnl\|CDD\|184146
NZ_FERW01000031.1\|WP_061727197.1\|0_913_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_FERW01000031.1\|WP_002235732.1\|3348_5259_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236861
NZ_FERW01000031.1\|WP_002213671.1\|8953_9436_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326

Protein	Function_ID	Function_description	E-value
NZ_FERW01000031.1\|WP_002219349.1\|11307_11913_+\|Smr/MutS-family-protein	gnl\|CDD\|225396	COG2840, COG2840, Uncharacterized protein conserved in bacteria [Function unknown].	1.08781e-65
NZ_FERW01000031.1\|WP_002219347.1\|7770_8907_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NZ_FERW01000031.1\|WP_002232360.1\|9541_10597_+\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	0
NZ_FERW01000031.1\|WP_042743482.1\|1704_2523_+\|adhesin-Opc	gnl\|CDD\|369279	pfam07239, OpcA, Outer membrane protein OpcA. This family consists of several Neisseria species specific OpcA outer membrane proteins. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and invasion of both epithelial and endothelial cells.	3.18e-132
NZ_FERW01000031.1\|WP_002219343.1\|2685_3330_+\|DedA-family-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	9.34832e-112
NZ_FERW01000031.1\|WP_042743485.1\|5755_7231_+\|anthranilate-synthase-component-I	gnl\|CDD\|184146	PRK13565, PRK13565, anthranilate synthase component I; Provisional.	0
NZ_FERW01000031.1\|WP_061727197.1\|0_913_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	1.80809e-60
NZ_FERW01000031.1\|WP_002235732.1\|3348_5259_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236861	PRK11147, PRK11147, ABC transporter ATPase component; Reviewed.	0
NZ_FERW01000031.1\|WP_002213671.1\|8953_9436_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.07635e-12

>NZ_FERW01000031.1|WP_061727197.1|0_913_+|IS5-family-transposase
QWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYSTLCRYRNWLAQDDTLSELLELINCQLTEKGLKVEKASAAVIDATIIQTAGSEQRQAIEVDEEGQVSGQTTLSKDKNARWTKKNSLYKLGYKQHTRTDAEGYIEKLYITPTNAHECTHLSPLLEGLPKGTTVYADKGYDSKENRQHLKEHRLQNGIMRKACRNRPLTETQTKRNRYLSKTRYSGLNLNQDKATKPQTVQIVRQGEATPYWFKFNPLYVVEQSFGTLHRKFRYARAAYFGLSKVSAQSHLKAMCLNLLKAANRLSAPAAA
>NZ_FERW01000031.1|WP_042743482.1|1704_2523_+|adhesin-Opc
MKKTVFTYAMIALTGTAAAAQELQTANEFTVHTDLSSISSTRAFLKEKHKAAKHIGVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVKLPTGVPENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDSIKTTKHTLHSSRQSWLAKVHADLLSQLGNGWYINPWSEVKFDLNSRYKLNTGVTSLKKDINQKTNGWGFGLGANIGKKLGESASIEAGPFYKQRTYKESGEFSVTTTSGDVSLTIPKTSIREYGLRVGIKF
>NZ_FERW01000031.1|WP_002219343.1|2685_3330_+|DedA-family-protein
MLASAIDFILHIDQHLLALSAQYGVWIYAILFLIVFCETGLIVTPLLPGDSLLFAAGGIAALGGMDIHLMVALLSLAAILGDALNFTVGKYFGGRLFANPDSKIFRREYLDKTHRFYEKHGGKTIIIARFMPIVRTFAPFVAGMGKMHYAKFIRYNIIGGLLWVILFSYAGYFFANFPVVKNNLGLVMGGIIIVSVLPGAVEIARAKLAVKSKR
>NZ_FERW01000031.1|WP_002235732.1|3348_5259_+|ATP-binding-cassette-domain-containing-protein
MNILSVENASFAIGHVALLDKTSFQLDSGEKVGLIGRNGAGKSSFLKILAGLQKLDDGQIIVQNNLKIVYVPQESFFDKDATVFDTVAEGLGEIRDLLRRYHHVSHDLEHNSDDVLLKELNELQLEIEAKDGWKLDAAVKQTLGELGLPENEKIGNLSGGQKKRVALAQAWVQKPDVLLLDEPTNHLDIDAIIWLENLLKAFEGSLVVITHDRRFLDNIATRIVELDRGILRSYPGSFSKYSEKKAQELAVEAEHNRLFDKFHAQEEAWIRKGIEARRTRNEGRVRRLEELRRQRAERRNVQGQVNFKLDSGEKSGKIIAELEHASFAYGGKVIMDKFSAILQRGDKIGLIGPNGIGKTTFLKLILGELQPTYGRIRIGSKQEVAYFDQFRSALNENDTVFYTLGQGNDYVEVGGKKKHVMSYLEDFLFPPARAQSPVSSLSGGERNRLLLAKLFTRPANILILDEPTNDLDIDTQELLEDLLRDYQGTVFLVSHDRMFLDNVITQSIIFEGNGRLKEYIGGYQDYIDAKSREAKIQTESAPKTADAEPVKEKPKANRTVKLSYKEQRELDALPDEIAALEAEQAEINAQLSDPEIFKDYEKAGALQSRAEEIEMLLLEKLERWELLETKQNGNAV
>NZ_FERW01000031.1|WP_002213667.1|5279_5645_+|hypothetical-protein
MFKRPEEIIVLILAVLWIAGTYFLAALFGADAYTVLKITALTLLWSAASFLLWQKNLSRHIWPLLLGCLTACWWPYLNQSVAPGSLPWYASWTFKTILALIPVTAGYLFKWKQYRQRKTKP
>NZ_FERW01000031.1|WP_042743485.1|5755_7231_+|anthranilate-synthase-component-I
MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVVDNLSGKIYLIVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQEGLDK
>NZ_FERW01000031.1|WP_002219347.1|7770_8907_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKNISLSPPATLGILGGGQLGRMFTVAAKTMGYKVTVLDPDPNAPAAEFADRHLCAPFNDQTALDELAKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVAIAQNRIQEKAWIRKAGLQTAPYQAVCKAEDITEASAQFLPGILKTATLGYDGKGQIRVKTVDELKAAFAEHGGVDCVLEKMVDLRGEISVIVCRLNNDNVQTFDPAENIHENGILAYSIVPARLSADIQQQARQMAQRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTVDACAADQFQQQVRLMCNLPPADTKLLSSCCMANILGDVWQEDGGEPDWFPLQSRPDAHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKKLHQSL
>NZ_FERW01000031.1|WP_002213671.1|8953_9436_+|GNAT-family-N-acetyltransferase
MNLLTLLRPATVQDCKDIFKVHLHSVQYTCILSYNEHALKVWEGLLNTESYLPTISDPDKALWVAEYKGNIQGFFQIDCQEAQLDALYVHPLFHNLGLGTALLHQAETIAHKSGLSFLKLYASLNSVPFYLLNRYESLGSAVLQLDPSIKIKCELMRKHL
>NZ_FERW01000031.1|WP_002232360.1|9541_10597_+|sulfate-ABC-transporter-substrate-binding-protein
MKTYAPALYTAALLTACSPAADSNHPSGQNAPANTESDGKNITLLNASYDVARDFYKEYNPLFIKTYQSEHPGTSVSIQQSHGGSSKQALSVANGLQADVVTMNQSSDIDLLEKKGLVEKGWQQALPDHAAPYTSTMVFLVRKNNPKQIRDWNDLAKDGVNIVIANPKTSGNGRYAFLGAYGYGLKATNGNEQEAQKLVASILKNTPVFENGGRAATTTFTQRNIGDVLITFENEANYVSKKLTQGQFEIVYPSYTISAESPVAVVNSVVAKKGTQKTARAYLEYLWSEPAQELAASLYLRPRNPEVLARHKADFPDLDTFSPEEKFGGWDNIMKTYFADGGIFDRLTAQK
>NZ_FERW01000031.1|WP_002237893.1|10593_10791_+|hypothetical-protein
MTAMPSEPPFRRHSTHQNRKTAPKIIITRHNGKPDTKPNTAAKMPSEAVGATILIWGITFLNHPF
>NZ_FERW01000031.1|WP_002219349.1|11307_11913_+|Smr/MutS-family-protein
MNTDFQNILKQLGKQAQKEAAEKQAAEKNKQKQEQDFDFSQAVGQVSPLKNRQQYYAPPDKTPIKVRPKDNRADEENYFYIGSTYNDPPASFSKNGQGKNDIQRLKNGYYPVVTDVDLHGYTQEEAQKVLNEFIAFTQKRGVCGEIIHGSGLGSKGYKPVLKNMTRNWLMQHPDVLAYAEPREGNDGCVRILLKRKLRQQD

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Crispr_ID: NZ_FERW01000031_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000031_2

1288-1468

Orphan

I-E

Consensus_repeat	Method
GATTCCCGCCTGCGCGGGAATGACG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_FERW01000031_2

>merge|NZ_FERW01000031|2|1288-1468|CRISPRCasFinder
CATTCCCGCGCAGGCGGGAATCTAGGTTTGTCGGCACAGAAACTTGTCGGGAAAAACGGTTTCTTTAGATTTTACGTTCTGGATTCCCGCCTGCGCGGGAATGACGATGAAAAGATTGTTGTCGCTTCGGATAAATTTTTACCGTGTTGGGTTCTAGATTCCCGCCTGAGCGGGAATGACG

>NZ_FERW01000031|2|2|1288-1468|CRISPRCasFinder
CATTCCCGCGCAGGCGGGAATCTAG	GTTTGTCGGCACAGAAACTTGTCGGGAAAAACGGTTTCTTTAGATTTTACGTTCTG
GATTCCCGCCTGCGCGGGAATGACG	ATGAAAAGATTGTTGTCGCTTCGGATAAATTTTTACCGTGTTGGGTTCTA
GATTCCCGCCTGAGCGGGAATGACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000031.1\|WP_002219349.1\|11307_11913_+\|Smr/MutS-family-protein	unknown	unknown	gnl\|CDD\|225396
NZ_FERW01000031.1\|WP_002219343.1\|2685_3330_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|182775
NZ_FERW01000031.1\|WP_002219347.1\|7770_8907_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_FERW01000031.1\|WP_002232360.1\|9541_10597_+\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224529
NZ_FERW01000031.1\|WP_042743482.1\|1704_2523_+\|adhesin-Opc	unknown	unknown	gnl\|CDD\|369279
NZ_FERW01000031.1\|WP_002213667.1\|5279_5645_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000031.1\|WP_002237893.1\|10593_10791_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000031.1\|WP_042743485.1\|5755_7231_+\|anthranilate-synthase-component-I	unknown	unknown	gnl\|CDD\|184146
NZ_FERW01000031.1\|WP_061727197.1\|0_913_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_FERW01000031.1\|WP_002235732.1\|3348_5259_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236861
NZ_FERW01000031.1\|WP_002213671.1\|8953_9436_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326

Protein	Function_ID	Function_description	E-value
NZ_FERW01000031.1\|WP_002219349.1\|11307_11913_+\|Smr/MutS-family-protein	gnl\|CDD\|225396	COG2840, COG2840, Uncharacterized protein conserved in bacteria [Function unknown].	1.08781e-65
NZ_FERW01000031.1\|WP_002219347.1\|7770_8907_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NZ_FERW01000031.1\|WP_002232360.1\|9541_10597_+\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	0
NZ_FERW01000031.1\|WP_042743482.1\|1704_2523_+\|adhesin-Opc	gnl\|CDD\|369279	pfam07239, OpcA, Outer membrane protein OpcA. This family consists of several Neisseria species specific OpcA outer membrane proteins. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and invasion of both epithelial and endothelial cells.	3.18e-132
NZ_FERW01000031.1\|WP_002219343.1\|2685_3330_+\|DedA-family-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	9.34832e-112
NZ_FERW01000031.1\|WP_042743485.1\|5755_7231_+\|anthranilate-synthase-component-I	gnl\|CDD\|184146	PRK13565, PRK13565, anthranilate synthase component I; Provisional.	0
NZ_FERW01000031.1\|WP_061727197.1\|0_913_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	1.80809e-60
NZ_FERW01000031.1\|WP_002235732.1\|3348_5259_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236861	PRK11147, PRK11147, ABC transporter ATPase component; Reviewed.	0
NZ_FERW01000031.1\|WP_002213671.1\|8953_9436_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.07635e-12

>NZ_FERW01000031.1|WP_061727197.1|0_913_+|IS5-family-transposase
QWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYSTLCRYRNWLAQDDTLSELLELINCQLTEKGLKVEKASAAVIDATIIQTAGSEQRQAIEVDEEGQVSGQTTLSKDKNARWTKKNSLYKLGYKQHTRTDAEGYIEKLYITPTNAHECTHLSPLLEGLPKGTTVYADKGYDSKENRQHLKEHRLQNGIMRKACRNRPLTETQTKRNRYLSKTRYSGLNLNQDKATKPQTVQIVRQGEATPYWFKFNPLYVVEQSFGTLHRKFRYARAAYFGLSKVSAQSHLKAMCLNLLKAANRLSAPAAA
>NZ_FERW01000031.1|WP_042743482.1|1704_2523_+|adhesin-Opc
MKKTVFTYAMIALTGTAAAAQELQTANEFTVHTDLSSISSTRAFLKEKHKAAKHIGVRADIPFDANQGIRLEAGFGRSKKNIINLETDENKLGKTKNVKLPTGVPENRIDLYTGYTYTQTLSDSLNFRVGAGLGFESSKDSIKTTKHTLHSSRQSWLAKVHADLLSQLGNGWYINPWSEVKFDLNSRYKLNTGVTSLKKDINQKTNGWGFGLGANIGKKLGESASIEAGPFYKQRTYKESGEFSVTTTSGDVSLTIPKTSIREYGLRVGIKF
>NZ_FERW01000031.1|WP_002219343.1|2685_3330_+|DedA-family-protein
MLASAIDFILHIDQHLLALSAQYGVWIYAILFLIVFCETGLIVTPLLPGDSLLFAAGGIAALGGMDIHLMVALLSLAAILGDALNFTVGKYFGGRLFANPDSKIFRREYLDKTHRFYEKHGGKTIIIARFMPIVRTFAPFVAGMGKMHYAKFIRYNIIGGLLWVILFSYAGYFFANFPVVKNNLGLVMGGIIIVSVLPGAVEIARAKLAVKSKR
>NZ_FERW01000031.1|WP_002235732.1|3348_5259_+|ATP-binding-cassette-domain-containing-protein
MNILSVENASFAIGHVALLDKTSFQLDSGEKVGLIGRNGAGKSSFLKILAGLQKLDDGQIIVQNNLKIVYVPQESFFDKDATVFDTVAEGLGEIRDLLRRYHHVSHDLEHNSDDVLLKELNELQLEIEAKDGWKLDAAVKQTLGELGLPENEKIGNLSGGQKKRVALAQAWVQKPDVLLLDEPTNHLDIDAIIWLENLLKAFEGSLVVITHDRRFLDNIATRIVELDRGILRSYPGSFSKYSEKKAQELAVEAEHNRLFDKFHAQEEAWIRKGIEARRTRNEGRVRRLEELRRQRAERRNVQGQVNFKLDSGEKSGKIIAELEHASFAYGGKVIMDKFSAILQRGDKIGLIGPNGIGKTTFLKLILGELQPTYGRIRIGSKQEVAYFDQFRSALNENDTVFYTLGQGNDYVEVGGKKKHVMSYLEDFLFPPARAQSPVSSLSGGERNRLLLAKLFTRPANILILDEPTNDLDIDTQELLEDLLRDYQGTVFLVSHDRMFLDNVITQSIIFEGNGRLKEYIGGYQDYIDAKSREAKIQTESAPKTADAEPVKEKPKANRTVKLSYKEQRELDALPDEIAALEAEQAEINAQLSDPEIFKDYEKAGALQSRAEEIEMLLLEKLERWELLETKQNGNAV
>NZ_FERW01000031.1|WP_002213667.1|5279_5645_+|hypothetical-protein
MFKRPEEIIVLILAVLWIAGTYFLAALFGADAYTVLKITALTLLWSAASFLLWQKNLSRHIWPLLLGCLTACWWPYLNQSVAPGSLPWYASWTFKTILALIPVTAGYLFKWKQYRQRKTKP
>NZ_FERW01000031.1|WP_042743485.1|5755_7231_+|anthranilate-synthase-component-I
MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYTYLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHNRFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVVDNLSGKIYLIVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALYRALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTLYVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQEGLDK
>NZ_FERW01000031.1|WP_002219347.1|7770_8907_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKNISLSPPATLGILGGGQLGRMFTVAAKTMGYKVTVLDPDPNAPAAEFADRHLCAPFNDQTALDELAKCAAVTTEFENVNADAMRFLAKHTNVSPSGDCVAIAQNRIQEKAWIRKAGLQTAPYQAVCKAEDITEASAQFLPGILKTATLGYDGKGQIRVKTVDELKAAFAEHGGVDCVLEKMVDLRGEISVIVCRLNNDNVQTFDPAENIHENGILAYSIVPARLSADIQQQARQMAQRLADELNYVGVLAVEMFVVGDTHELVVNEIAPRPHNSGHHTVDACAADQFQQQVRLMCNLPPADTKLLSSCCMANILGDVWQEDGGEPDWFPLQSRPDAHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKKLHQSL
>NZ_FERW01000031.1|WP_002213671.1|8953_9436_+|GNAT-family-N-acetyltransferase
MNLLTLLRPATVQDCKDIFKVHLHSVQYTCILSYNEHALKVWEGLLNTESYLPTISDPDKALWVAEYKGNIQGFFQIDCQEAQLDALYVHPLFHNLGLGTALLHQAETIAHKSGLSFLKLYASLNSVPFYLLNRYESLGSAVLQLDPSIKIKCELMRKHL
>NZ_FERW01000031.1|WP_002232360.1|9541_10597_+|sulfate-ABC-transporter-substrate-binding-protein
MKTYAPALYTAALLTACSPAADSNHPSGQNAPANTESDGKNITLLNASYDVARDFYKEYNPLFIKTYQSEHPGTSVSIQQSHGGSSKQALSVANGLQADVVTMNQSSDIDLLEKKGLVEKGWQQALPDHAAPYTSTMVFLVRKNNPKQIRDWNDLAKDGVNIVIANPKTSGNGRYAFLGAYGYGLKATNGNEQEAQKLVASILKNTPVFENGGRAATTTFTQRNIGDVLITFENEANYVSKKLTQGQFEIVYPSYTISAESPVAVVNSVVAKKGTQKTARAYLEYLWSEPAQELAASLYLRPRNPEVLARHKADFPDLDTFSPEEKFGGWDNIMKTYFADGGIFDRLTAQK
>NZ_FERW01000031.1|WP_002237893.1|10593_10791_+|hypothetical-protein
MTAMPSEPPFRRHSTHQNRKTAPKIIITRHNGKPDTKPNTAAKMPSEAVGATILIWGITFLNHPF
>NZ_FERW01000031.1|WP_002219349.1|11307_11913_+|Smr/MutS-family-protein
MNTDFQNILKQLGKQAQKEAAEKQAAEKNKQKQEQDFDFSQAVGQVSPLKNRQQYYAPPDKTPIKVRPKDNRADEENYFYIGSTYNDPPASFSKNGQGKNDIQRLKNGYYPVVTDVDLHGYTQEEAQKVLNEFIAFTQKRGVCGEIIHGSGLGSKGYKPVLKNMTRNWLMQHPDVLAYAEPREGNDGCVRILLKRKLRQQD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000031_1	1.1\|1115\|52\|NZ_FERW01000031\|CRISPRCasFinder	1115-1166	52	NZ_FERW01000050.1	321-372	2	0.962
NZ_FERW01000031_2	2.2\|1394\|50\|NZ_FERW01000031\|CRISPRCasFinder	1394-1443	50	NZ_FERW01000009.1	5630-5679	1	0.98
NZ_FERW01000031_2	2.2\|1394\|50\|NZ_FERW01000031\|CRISPRCasFinder	1394-1443	50	NZ_FERW01000009.1	5907-5956	1	0.98

1. spacer 1.1|1115|52|NZ_FERW01000031|CRISPRCasFinder matches to position: 321-372, mismatch: 2, identity: 0.962

acccccaacgcggcaggaatctatcggaaataaccgaaaccggacgaaccta	CRISPR spacer
accaccaacgcggcaggaatctatcggaaataaccgaaaccagacgaaccta	Protospacer
*** *************************************.**********

2. spacer 2.2|1394|50|NZ_FERW01000031|CRISPRCasFinder matches to position: 5630-5679, mismatch: 1, identity: 0.98

atgaaaagattgttgtcgcttcggataaatttttaccgtgttgggttcta	CRISPR spacer
atgaaaagattgttgtcgcttcggataaatttttgccgtgttgggttcta	Protospacer
**********************************.***************

3. spacer 2.2|1394|50|NZ_FERW01000031|CRISPRCasFinder matches to position: 5907-5956, mismatch: 1, identity: 0.98

atgaaaagattgttgtcgcttcggataaatttttaccgtgttgggttcta	CRISPR spacer
atgaaaagattgttgtcgcttcggataaatttttgccgtgttgggttcta	Protospacer
**********************************.***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000007_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000007_1

43230-43401

Orphan

I-E

Consensus_repeat	Method
CCGTCATTCCCGCGCAGGCGGGAATC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_FERW01000007_1

>merge|NZ_FERW01000007|1|43230-43401|CRISPRCasFinder
CCGTCATTCCCGCGCAGGCGGGAATCCGACTTGTCCGGTTTTGGTTGTTTTTCGTTCCGTAACTTTTGAGCCGTCATTCCCGCGCAGGCGGGAATCTAGAATTTCAATGCCTCAAGAATTTATCGGAAAAAACCAAAACCCTTCCGCCGTCATTCCCACGAAAGTGGGAATC

>NZ_FERW01000007|1|1|43230-43401|CRISPRCasFinder
CCGTCATTCCCGCGCAGGCGGGAATC	CGACTTGTCCGGTTTTGGTTGTTTTTCGTTCCGTAACTTTTGAG
CCGTCATTCCCGCGCAGGCGGGAATC	TAGAATTTCAATGCCTCAAGAATTTATCGGAAAAAACCAAAACCCTTCCG
CCGTCATTCCCACGAAAGTGGGAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000007.1\|WP_041422262.1\|44260_45340_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|234565
NZ_FERW01000007.1\|WP_002214520.1\|50587_51187_-\|PilN-domain-containing-protein	unknown	unknown	gnl\|CDD\|225707
NZ_FERW01000007.1\|WP_002214509.1\|55808_56432_+\|cytochrome-c4	unknown	unknown	gnl\|CDD\|225418
NZ_FERW01000007.1\|WP_042743597.1\|32258_34169_-\|NADH-dependent-dehydratase-PglD	unknown	unknown	gnl\|CDD\|224011
NZ_FERW01000007.1\|WP_042743601.1\|34216_35392_-\|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223476
NZ_FERW01000007.1\|WP_041422260.1\|45419_45932_-\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_FERW01000007.1\|WP_002248535.1\|47072_49358_-\|type-IV-pilus-secretin-PilQ	unknown	unknown	gnl\|CDD\|227133
NZ_FERW01000007.1\|WP_042743594.1\|39007_40429_-\|lipopolysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|225153
NZ_FERW01000007.1\|WP_002222980.1\|42257_43100_-\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|372525
NZ_FERW01000007.1\|WP_002219786.1\|52456_54853_+\|penicillin-binding-protein-1A	unknown	unknown	gnl\|CDD\|227342
NZ_FERW01000007.1\|WP_061727186.1\|36756_37926_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340825
NZ_FERW01000007.1\|WP_002214517.1\|51189_52305_-\|pilus-assembly-protein-PilM	unknown	unknown	gnl\|CDD\|227306
NZ_FERW01000007.1\|WP_002258334.1\|40623_41733_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NZ_FERW01000007.1\|WP_002217908.1\|49939_50587_-\|type-4a-pilus-biogenesis-protein-PilO	unknown	unknown	gnl\|CDD\|225708
NZ_FERW01000007.1\|WP_002258333.1\|41764_42229_-\|transcriptional-repressor-NrdR	unknown	unknown	gnl\|CDD\|224246
NZ_FERW01000007.1\|WP_079763237.1\|37939_38476_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340846
NZ_FERW01000007.1\|WP_042743598.1\|30908_32201_-\|valine--pyruvate-transaminase	unknown	unknown	gnl\|CDD\|226485
NZ_FERW01000007.1\|WP_002217909.1\|49376_49922_-\|pilus-assembly-protein-PilP	unknown	unknown	gnl\|CDD\|225709
NZ_FERW01000007.1\|WP_002217904.1\|54973_55603_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NZ_FERW01000007.1\|WP_042743596.1\|35522_36764_-\|UDP-N-acetylgalactosaminyltransferase	unknown	unknown	gnl\|CDD\|376775

Protein	Function_ID	Function_description	E-value
NZ_FERW01000007.1\|WP_041422262.1\|44260_45340_-\|3-dehydroquinate-synthase	gnl\|CDD\|234565	PRK00002, aroB, 3-dehydroquinate synthase; Reviewed.	0
NZ_FERW01000007.1\|WP_002214520.1\|50587_51187_-\|PilN-domain-containing-protein	gnl\|CDD\|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	2.93941e-62
NZ_FERW01000007.1\|WP_002214509.1\|55808_56432_+\|cytochrome-c4	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	1.06154e-40
NZ_FERW01000007.1\|WP_042743597.1\|32258_34169_-\|NADH-dependent-dehydratase-PglD	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_FERW01000007.1\|WP_042743601.1\|34216_35392_-\|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	gnl\|CDD\|223476	COG0399, WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane].	9.14012e-160
NZ_FERW01000007.1\|WP_041422260.1\|45419_45932_-\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	2.55273e-76
NZ_FERW01000007.1\|WP_002248535.1\|47072_49358_-\|type-IV-pilus-secretin-PilQ	gnl\|CDD\|227133	COG4796, HofQ, Type II secretory pathway, component HofQ [Intracellular trafficking and secretion].	0
NZ_FERW01000007.1\|WP_042743594.1\|39007_40429_-\|lipopolysaccharide-biosynthesis-protein	gnl\|CDD\|225153	COG2244, RfbX, Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only].	5.87705e-29
NZ_FERW01000007.1\|WP_002222980.1\|42257_43100_-\|class-II-glutamine-amidotransferase	gnl\|CDD\|372525	pfam13230, GATase_4, Glutamine amidotransferases class-II. This family captures members that are not found in pfam00310.	1.00926e-141
NZ_FERW01000007.1\|WP_002219786.1\|52456_54853_+\|penicillin-binding-protein-1A	gnl\|CDD\|227342	COG5009, MrcA, Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane].	0
NZ_FERW01000007.1\|WP_061727186.1\|36756_37926_-\|glycosyltransferase	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.2635e-30
NZ_FERW01000007.1\|WP_002214517.1\|51189_52305_-\|pilus-assembly-protein-PilM	gnl\|CDD\|227306	COG4972, PilM, Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion].	2.23923e-147
NZ_FERW01000007.1\|WP_002258334.1\|40623_41733_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	8.13736e-123
NZ_FERW01000007.1\|WP_002217908.1\|49939_50587_-\|type-4a-pilus-biogenesis-protein-PilO	gnl\|CDD\|225708	COG3167, PilO, Tfp pilus assembly protein PilO [Cell motility and secretion / Intracellular trafficking and secretion].	3.93473e-90
NZ_FERW01000007.1\|WP_002258333.1\|41764_42229_-\|transcriptional-repressor-NrdR	gnl\|CDD\|224246	COG1327, COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains [Transcription].	7.57936e-72
NZ_FERW01000007.1\|WP_079763237.1\|37939_38476_-\|glycosyltransferase	gnl\|CDD\|340846	cd03819, GT4_WavL-like, Vibrio cholerae WavL and similar sequences. This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.	1.19422e-41
NZ_FERW01000007.1\|WP_042743598.1\|30908_32201_-\|valine--pyruvate-transaminase	gnl\|CDD\|226485	COG3977, COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase [Amino acid transport and metabolism].	0
NZ_FERW01000007.1\|WP_002217909.1\|49376_49922_-\|pilus-assembly-protein-PilP	gnl\|CDD\|225709	COG3168, PilP, Tfp pilus assembly protein PilP [Cell motility and secretion / Intracellular trafficking and secretion].	3.31046e-85
NZ_FERW01000007.1\|WP_002217904.1\|54973_55603_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	6.45243e-104
NZ_FERW01000007.1\|WP_042743596.1\|35522_36764_-\|UDP-N-acetylgalactosaminyltransferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	5.70665e-96

>NZ_FERW01000007.1|WP_002222980.1|42257_43100_-|class-II-glutamine-amidotransferase
MCQLLGMNCNTPTDIMFSFEGFRRRGGITDHHADGFGIGFFEGKGVRLFHDDKPSANSPVADLVRAYQIKSENVVAHIRKASQGQTSLANTHPFMREMWGGYWLFAHNGHLIDFFPEQGEFFHPVGTTDSERAFCHILNRLRTRFAARPDDDTLFDAIAGLTHEIRKFGLFNFMLSDGIALFAHASTLLHYIVRQAPFGKARLLDDDVMVDFAEVTTPSDRVAVIATLPLTRDESWSQLAVDELVMFREGNIVRHDRPENPVYMSAEEGLEIARAAGVSV
>NZ_FERW01000007.1|WP_002258333.1|41764_42229_-|transcriptional-repressor-NrdR
MKCPFCAHPDTRVADSRLMEERNAVRRRRHCPSCGKRFGTLETAELKMPAVIGPDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRDIPSTELADMVLKELLEHNTEAAIRFAALHKRFDSPEHFASWLAQAVKTGGKA
>NZ_FERW01000007.1|WP_002258334.1|40623_41733_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MFSDTDISMMETALRLAALGRFSTSPNPRVGCVIAHGSQIVGQGFHVKAGEPHAEVHALRQAGEMAQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAAMRDPNPLVAGKGLALLEAAGIKTECGLLEHQARKLNRGFLSRIERRRPFVRLKCAVSLDGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQPARIVLDSRLRLPPNSHLVTDGQSPTYIATLERNEDRLHPYREHAHVRILMPSETADGKIDLHHLMRLLADEGFGEIMVEAGSELTSAFLAEDLADEIVLYRSPKILGGGSGLFCLPENRAALSAPPLWTPVSSEILGHDIKTVFRKNDNAF
>NZ_FERW01000007.1|WP_042743594.1|39007_40429_-|lipopolysaccharide-biosynthesis-protein
MDTKEILGYAAGSIGSAVLAVIILPLLSWYFPADDIGRIVLMQTAAGLTVSVLCLGLDQAYVREYYAAADKDTLFKTLFLPPLLSAAAIAALLLSRPSLPSEILFSLDDAAAGIGLVLFELSFLPIRFLLLVLRMEGRALAFSSAQLVPKLAILLLLPLTIGLLHFPANTAVLTAVYALANLAAAAFLLFQNRCRLKAVRHAPFSPAVLHRGLRYGIPIALSSIAYWGLASADRLFLKKYAGLEQLGVYSMGISFGGAALLFQSIFSTVWTPYIFRAIEENAPPARLSATAESAAALLASALCLTGIFSPLASLLLPENYAAVRFIVVSCMLPPLFCTLVEISGIGLNVVRKTRPIALATLGALAANLLLLGLAVPSGGARGAAVACAASFWLFFAFKTESSCRLWQPLKRLPLYTHTLLCLTSSAAYTCFGTPANYPLFAGVWAAYLAGCILRHRKDLHKLFHYLKKQGFPL
>NZ_FERW01000007.1|WP_079763237.1|37939_38476_-|glycosyltransferase
MLGTLSRLDTVRAVHLMLDIFKKMVDRDMPVRLNVAGIGEEMDNLKAQAERLGIDGKVTFLGGIRDLTAYFKDVDILVNTPHCIGDHGAGVGNNILEAGLYDTPVVTYDMAGISEMVVNGETGYCIPFGDEEAFIAAVDTLVRQPELREAMGKRLHAHVAALCSDDEIYRTTMAAYEM
>NZ_FERW01000007.1|WP_061727186.1|36756_37926_-|glycosyltransferase
MNITIVAPYCSLPSEPYFNRFWYLAERLSQSHDVLLITSRFRHYDKSFRRHEDAEAASQGRLKVMLLEESGYGKNVSLERVASHYRFVKNFEQWLKNCRPGEQDIVYSAYPLIATNLLLGKHKARLGYKLIVDVQDVWPESFSSVVPFLKKVPHKLLPFASRANRAYRCADALVAVSQTYLDRAKEANPNVPGEAVYIGTDFAAIAPPPPRFRSKTVRLFYLGTLSYSYDVETVCKGVRKLLDDGENVELHVMGGGPDLEKLKQYENRAIKFYGYLPYSEMMSIAKACDIAVNAIHSHAMQSVTNKLSDYMALQKPILNSQTNAEVLSLLNLLPHENYRSGDVDSFVQAAKDILKRKNDPVQSDEIVRRFRRDISYRKIVNLIERLANE
>NZ_FERW01000007.1|WP_042743596.1|35522_36764_-|UDP-N-acetylgalactosaminyltransferase
MSKAVKRLFDIIASASGLIVLSPVFLILAYLIRKNLGSPVFFIQERPGKDGKPFKMIKFRSMRDALDSDGIPLPDGERLTPFGKKLRAASLDELPELWNVLKGEMSLVGPRPLLMQYLPLYDNFQNRRHEMKPGITGWAQVNGRNALSWDEKFACDVWYIDHYSFWLDMKILFLTVRKVLIKEGISAQGEATMPPFTGKRKLAVVGAGGHGKVVADLAAALGTYGEIVFLDDRAQGSIDGFPVIGTTLLLENGLSPEQFDIAVAVGNNRIRRQIAGRAAALGFKLPVLIHPLAYVSPSATVGQGSVVMAQAVVQAGSVLKDGVIVNTAATIDHDCLLDAFVHISPGAHLSGNTRIGEESWIGTGACSRQQIRIGSRATIGAGAVVVRDVSDGITVAGNPAKPLPRKNPETSTA
>NZ_FERW01000007.1|WP_042743601.1|34216_35392_-|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein
MLNTSLSPWPCFTQEEADAVSKVLLSNKVNYWTGSECREFEKEFAAFAGTRYAVTLSNGTLALDVALKAMGIGAGDDVIVTSRTFLASASCIVNAGANPVFADVDLNSQNISAETVKAALTPNTKAVIVVHLAGMPAEMDGIMDLAKEHDLWVIEDCAQAHGAKYKGKSVGSIGHVGAWSFCQDKIMTTGGEGGMVTTNDKTLWEKMWSYKDHGKSYDAVYHREHAPGFRWLHESFGTNWRMMEMQAVIGRIQLKRMPEWTARRQAHAAKLAESLGKFASIRLIEVADYIEHAQYKFYAFVKPEHLKDGWTRDRIVGELNARKVPCYQGSCSEVYLEKAFDNTPWRPKERLTNAVELGDTSLMFLVHPTLTDDEIAFCKKHIEAVLTEAAR
>NZ_FERW01000007.1|WP_042743597.1|32258_34169_-|NADH-dependent-dehydratase-PglD
MTLETLLALPRNIKKICFLIHDFLMIFIAFWFTQSLKADYSNEWFDPANWQSFLLTALLTIGLFVRMGLYRAVTRFVSFHVLTTAFAGSIVSAVLFFLNTLIFEERLRLALPIVYFLLLFVSVTGSRMVLRGLLSEHPKKQMIPVIIYGAGRSGRQLLEAVKQMREYSAAAFVDDDPKLWHTVIYDLAVYQPDAIAFLIERYGVEKILLAIPGATQEQRLRIINKLEAYPCEVLTIPGMKDLMDGKISIGTLKKISVSDLLGRDSVAPDDRLMNADIEGKTVMVTGAGGSIGSELCRQIIRRRPEKLLLFELSEFALYAIEKELRETCIQKRLDTEILPFLGSVQNRTLLEHVMTAFSVATVYHAAAYKHVPMVEFNTVEGIRNNIFGTLECALAATASGVRTFVLISTDKAVRPTNTMGAGKRMAELCLQALAAEPGQKTRFSMVRFGNVLGSSGSVVPLFEKQIAEGGPLTLTHPEITRYFMTIPEAAQLVIQAGAMGTGGDIFVLDMGESVKIIDLARQMITLSGLKPKTPEQPDGDIEILITGLRPGEKLYEELLIGDNVRKTGHPRIMTADEAMLPWHELSVLLDRIRAACDRYDQQAIRTLLINAPTGFTPSDGICDLLWVRETHRKNAV
>NZ_FERW01000007.1|WP_042743598.1|30908_32201_-|valine--pyruvate-transaminase
MQFSAFGEKFTQHSGILQLMDDLGDALKSDKPVNMLGGGNPARIPEIDRAFADIFSKLAAEHAVENIGNYSNPQGDAALIDALAAFLNREYGWNLTADNIALTNGSQNAFFYLFNLFGGKFNLSDGTSAEKAILLPLAPEYIGYADVHVEGQHFVSVKPKIENVEHEGEAGFFKYRVDFDALENLPELKAGKIGAICCSRPTNPTGNVLTDGEMARLDALAREHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILCFSLSKVGLPGVRTGIIVAAPEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLLKRELGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTQDYPHAGECIRMSIAQDAQTLEKGIAAIGKTVRKLYDNV
>NZ_FERW01000007.1|WP_041422262.1|44260_45340_-|3-dehydroquinate-synthase
MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLHTLQTALDAAGVSHFSIILPDGEAYKNWQTLNLIFDGLMQHRAERKTTLIALGGGVIGDMVGFAAATYQRGAPFIQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGTLGDISFFEWLEQHMPELMALERAPLIQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAIAAGCVLAARLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGLNRLGEANITEITDTDILRRTLQPYL
>NZ_FERW01000007.1|WP_041422260.1|45419_45932_-|shikimate-kinase
MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVVYLHAPPEILLERTRCDNSRPLLQVADPLEKLRELYAARDPVYRQTADFTVESANCRETVQTLLKRLSR
>NZ_FERW01000007.1|WP_002248535.1|47072_49358_-|type-IV-pilus-secretin-PilQ
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQATAPSTKSAVSVSKPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQTAAPAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY
>NZ_FERW01000007.1|WP_002217909.1|49376_49922_-|pilus-assembly-protein-PilP
MKHYALLISFLALSACSQGSEDLNEWMAQTRREAKAEIIPFQAPTLPVAPVYSPPQLTGPNAFDFRRMETDKKGENAPDTKRIKETLEKFSLENMRYVGILKSGQKVSGFIEAEGYVYTVGVGNYLGQNYGRIESITDNSIVLNELIEDSTGNWVSRKAELLLNSSDKNTEQAAAPAAEQN
>NZ_FERW01000007.1|WP_002217908.1|49939_50587_-|type-4a-pilus-biogenesis-protein-PilO
MASKSSKTNLDLNNLHLLNLPARLFIALLAVAAVLGLGYAGLFKSQMESLEEYEAKETELKNTYKQKSIDAASLNNLRDELASIRSAFDIMLKQLPTDAEIPNLVQELHQAGSSNGLRLDSVMPQPPVDDGPIKRLPYSISITGNYEQISQFTRDVGSLSRIITLESLKIAQSPENGGNPDGKSSILNLSAIATTYQAKSVEELAAEAAQNAEQK
>NZ_FERW01000007.1|WP_002214520.1|50587_51187_-|PilN-domain-containing-protein
MNNLIKINLLPYREEMNKRKQQQFKTLMYGAVLTGVAAVAATYLFIDNMINNQSERNTLLETSIAHLDTELSEIQKLKQEKDAFLIKKNKIEELQLKRLQAAKILDSLNEAVPGSTYLTSLDAVTADSYRLSGRTSSDNRVAAMMRAMPNTGIFKQPELLSIKKNNSHQEFTLQATLQPIVKAAESKENPASGNAQEAN
>NZ_FERW01000007.1|WP_002214517.1|51189_52305_-|pilus-assembly-protein-PilM
MRLFKSLKNPKKTDAKLPKKSSGLNNRAAIGIDIDQHSIKMVQLSGRSLNQIQLEKYVIAKLPKNIIQGNKVQNYDQLVTYLQQAYAKLGTSCKNIIASVPQNLATIEQLTYTDKDAELDLQGFVESSISEVSSISLEEANYDYQVLSQSAAGEAVLAVASRKDEIEPLIDAFNAAGMKLSALDVDIFGQYNAYALWINHFAPELAAEKVAIFGVYAAQTYALVIQDGKILYKQETSVSEEQLNQLIQRTYQVTEEKAEEIINSPQKPSDYQESVANYFNQQITQEIQRVLQFYYTTQTADDMTDIKHILLTGEAARQEGIAQTVASQTNADVQCVHPARYFADNLKTDKQQFELDAPTLTRAFGLAVRGL
>NZ_FERW01000007.1|WP_002219786.1|52456_54853_+|penicillin-binding-protein-1A
MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLTLDNSGIAPQPSRRAKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF
>NZ_FERW01000007.1|WP_002217904.1|54973_55603_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MNLFQNAKFFTTVNHLKDLPDTPLEIAFVGRSNAGKSSAINTLTNHVRLAYVSKTPGRTQHINFFELQNGNFMVDLPGYGYAQVPEAVRAHWVNLLGDYLQQRKQLIGLVLIMDARHPLKELDIRMLDFFHTTGRPVHILLSKADKLSKNEQIKTLSQVKKLLKPYSDRQNISVQLFSSLKKQGIDEANRTVGSWFDAADAAASSPKEN
>NZ_FERW01000007.1|WP_002214509.1|55808_56432_+|cytochrome-c4
MKRLTLLAFVLAAGAVSASPKADVEKGKQVAATVCAACHAADGNSGIAMYPRLAAQHTAYIYHQTIGIRDGKRTHGSAAVMKPVVMNLSDQDILNVSAFYAKQQPKSGEANPKENPELGAKIYRGGLSDKKVPACMSCHGPSGAGMPGGGSEIQAYPRLGGQHQAYIVEQMNAYKSGQRKNTIMEDIANRMSEEDLKAVANFIQGLR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000007_1	1.2\|43326\|50\|NZ_FERW01000007\|CRISPRCasFinder	43326-43375	50	NZ_FERW01000007.1	43850-43899	0	1.0
NZ_FERW01000007_1	1.2\|43326\|50\|NZ_FERW01000007\|CRISPRCasFinder	43326-43375	50	NZ_FERW01000011.1	78961-79010	0	1.0
NZ_FERW01000007_1	1.2\|43326\|50\|NZ_FERW01000007\|CRISPRCasFinder	43326-43375	50	NZ_FERW01000029.1	24336-24385	0	1.0
NZ_FERW01000007_1	1.2\|43326\|50\|NZ_FERW01000007\|CRISPRCasFinder	43326-43375	50	NZ_FERW01000029.1	23909-23958	1	0.98
NZ_FERW01000007_1	1.2\|43326\|50\|NZ_FERW01000007\|CRISPRCasFinder	43326-43375	50	NZ_FERW01000030.1	39-88	0	1.0

1. spacer 1.2|43326|50|NZ_FERW01000007|CRISPRCasFinder matches to position: 43850-43899, mismatch: 0, identity: 1.0

tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	CRISPR spacer
tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	Protospacer
**************************************************

2. spacer 1.2|43326|50|NZ_FERW01000007|CRISPRCasFinder matches to position: 78961-79010, mismatch: 0, identity: 1.0

tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	CRISPR spacer
tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	Protospacer
**************************************************

3. spacer 1.2|43326|50|NZ_FERW01000007|CRISPRCasFinder matches to position: 24336-24385, mismatch: 0, identity: 1.0

tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	CRISPR spacer
tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	Protospacer
**************************************************

4. spacer 1.2|43326|50|NZ_FERW01000007|CRISPRCasFinder matches to position: 23909-23958, mismatch: 1, identity: 0.98

tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	CRISPR spacer
tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacctttccg	Protospacer
********************************************.*****

5. spacer 1.2|43326|50|NZ_FERW01000007|CRISPRCasFinder matches to position: 39-88, mismatch: 0, identity: 1.0

tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	CRISPR spacer
tagaatttcaatgcctcaagaatttatcggaaaaaaccaaaacccttccg	Protospacer
**************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17553 : 27546

Vibrio_phage(25.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014580636.1\|17553_18192_-	hypothetical protein	A0A0M3LP90	Mannheimia_phage	6.6e-64	56.4
WP_042743705.1\|18188_18464_-	phage associated protein	NA	NA	NA	NA
WP_042743704.1\|18617_18950_-	hypothetical protein	NA	NA	NA	NA
WP_051754764.1\|19081_19369_-	hypothetical protein	NA	NA	NA	NA
WP_002255718.1\|19365_19842_-	hypothetical protein	B5AXA3	Iodobacteriophage	2.2e-24	64.2
WP_042743703.1\|19874_20075_-	hypothetical protein	NA	NA	NA	NA
WP_079763233.1\|20384_20945_-	hypothetical protein	NA	NA	NA	NA
WP_002212401.1\|20944_21643_-	helix-turn-helix domain-containing protein	Q7Y5W5	Haemophilus_phage	3.1e-51	58.1
WP_079763232.1\|21756_21987_+	hypothetical protein	NA	NA	NA	NA
WP_042743707.1\|22089_22986_+	hypothetical protein	A0A0P0IKQ2	Acinetobacter_phage	3.7e-12	49.3
WP_042743702.1\|22996_23773_+	ATP-binding protein	A0A059WFK9	Vibrio_phage	5.8e-38	35.4
WP_042743700.1\|24100_24793_+	hypothetical protein	U4KJA1	Streptococcus_phage	1.8e-14	32.9
WP_042743699.1\|24807_25266_+	hypothetical protein	NA	NA	NA	NA
WP_014580647.1\|25630_25780_+	hypothetical protein	NA	NA	NA	NA
WP_061727184.1\|25911_26460_+	RusA family crossover junction endodeoxyribonuclease	NA	NA	NA	NA
WP_014580650.1\|26650_27256_+	DUF1367 family protein	I3PV01	Vibrio_phage	4.7e-35	38.0
WP_041267007.1\|27252_27546_+	DUF1364 domain-containing protein	E5AGG0	Erwinia_phage	2.1e-25	55.2

Anti-CRISPR protein detection

Acr_ID: NZ_FERW01000005.1|WP_042743676.1|56272_56623_-|anti-CRISPR-protein-AcrIIC3

Click the colored protein region to show detailed information

Acr_ID: NZ_FERW01000005.1|WP_042743678.1|55855_56227_-|anti-CRISPR-protein-AcrIIC2

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_FERW01000005.1|WP_042743676.1|56272_56623_-|anti-CRISPR-protein-AcrIIC3

56272_56623_-

116 aa aa

AcrIIC3

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR0119\|WP_042743676.1\|AcrIIC3\|II-C\|Verified\|Neisseria-meningitidis	1.0	1	1.0

NZ_FERW01000005.1_55653_55863_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
NZ_FERW01000005.1_55653_55863_-	AcrIIC2-Aca3\|WP_042743680.1	1.0	1	1.0

NZ_FERW01000005.1|WP_042743678.1|55855_56227_-|anti-CRISPR-protein-AcrIIC2

55855_56227_-

123 aa aa

NZ_FERW01000005.1_55653_55863_-

Protein_id	Hit_Aca_id	Identity	Query_coverage	Hit_coverage
NZ_FERW01000005.1_55653_55863_-	AcrIIC2-Aca3\|WP_042743680.1	1.0	1	1.0

4. NZ_FERW01000011

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_FERW01000016

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000016_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000016_1

39324-39407

Orphan

I-E

Consensus_repeat	Method
CCGTCATTCCCGCGAAAGCGGGAATCTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000016_1

>merge|NZ_FERW01000016|1|39324-39407|CRISPRCasFinder
CCGTCATTCCCGCGAAAGCGGGAATCTAGGACGCAGGGTTAAGAAAACCTACATCCCGTCATTCCCGCGAAAGCGGGAATCTAG

>NZ_FERW01000016|1|1|39324-39407|CRISPRCasFinder
CCGTCATTCCCGCGAAAGCGGGAATCTAG	GACGCAGGGTTAAGAAAACCTACATC
CCGTCATTCCCGCGAAAGCGGGAATCTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000016.1\|WP_002219448.1\|40410_41817_+\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NZ_FERW01000016.1\|WP_042743551.1\|42125_42791_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|227305
NZ_FERW01000016.1\|WP_002220668.1\|34990_35851_-\|sulfate-ABC-transporter-permease-subunit-CysW	unknown	unknown	gnl\|CDD\|226665
NZ_FERW01000016.1\|WP_002222665.1\|32337_33864_+\|threonine-ammonia-lyase,-biosynthetic	unknown	unknown	gnl\|CDD\|236417
NZ_FERW01000016.1\|WP_002225363.1\|37347_37680_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000016.1\|WP_042743553.1\|44408_45005_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|227070
NZ_FERW01000016.1\|WP_061375311.1\|28205_30857_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226115
NZ_FERW01000016.1\|WP_042743457.1\|46747_47935_+\|succinyldiaminopimelate-transaminase	unknown	unknown	gnl\|CDD\|236393
NZ_FERW01000016.1\|WP_021439037.1\|31020_32190_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_FERW01000016.1\|WP_042743559.1\|42823_43444_+\|type-IV-pilus-modification-protein-PilV	unknown	unknown	gnl\|CDD\|227302
NZ_FERW01000016.1\|WP_002213852.1\|38011_38521_+\|isoprenylcysteine-carboxyl-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224669
NZ_FERW01000016.1\|WP_002235690.1\|48197_48977_+\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_FERW01000016.1\|WP_021439317.1\|39661_40249_-\|superoxide-dismutase	unknown	unknown	gnl\|CDD\|223678
NZ_FERW01000016.1\|WP_042743552.1\|43440_44430_+\|PilW-family-protein	unknown	unknown	gnl\|CDD\|227301
NZ_FERW01000016.1\|WP_002222651.1\|46218_46671_+\|dUTP-diphosphatase	unknown	unknown	gnl\|CDD\|234802
NZ_FERW01000016.1\|WP_002213865.1\|25113_25686_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_FERW01000016.1\|WP_042743554.1\|44994_45483_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|288394
NZ_FERW01000016.1\|WP_079758463.1\|26060_27971_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NZ_FERW01000016.1\|WP_002240448.1\|33920_34994_-\|sulfate/molybdate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224043
NZ_FERW01000016.1\|WP_002217475.1\|36220_37057_-\|sulfate-ABC-transporter-permease-subunit-CysT	unknown	unknown	gnl\|CDD\|131194

Protein	Function_ID	Function_description	E-value
NZ_FERW01000016.1\|WP_002219448.1\|40410_41817_+\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_FERW01000016.1\|WP_042743551.1\|42125_42791_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	1.39051e-58
NZ_FERW01000016.1\|WP_002220668.1\|34990_35851_-\|sulfate-ABC-transporter-permease-subunit-CysW	gnl\|CDD\|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	5.24191e-154
NZ_FERW01000016.1\|WP_002222665.1\|32337_33864_+\|threonine-ammonia-lyase,-biosynthetic	gnl\|CDD\|236417	PRK09224, PRK09224, threonine ammonia-lyase IlvA.	0
NZ_FERW01000016.1\|WP_002217475.1\|36220_37057_-\|sulfate-ABC-transporter-permease-subunit-CysT	gnl\|CDD\|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	6.67108e-142
NZ_FERW01000016.1\|WP_042743553.1\|44408_45005_+\|pilus-assembly-protein	gnl\|CDD\|227070	COG4726, PilX, Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion].	1.33147e-71
NZ_FERW01000016.1\|WP_061375311.1\|28205_30857_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226115	COG3587, COG3587, Restriction endonuclease [Defense mechanisms].	8.02442e-137
NZ_FERW01000016.1\|WP_042743457.1\|46747_47935_+\|succinyldiaminopimelate-transaminase	gnl\|CDD\|236393	PRK09147, PRK09147, succinyldiaminopimelate transaminase; Provisional.	0
NZ_FERW01000016.1\|WP_021439037.1\|31020_32190_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	1.88346e-130
NZ_FERW01000016.1\|WP_042743559.1\|42823_43444_+\|type-IV-pilus-modification-protein-PilV	gnl\|CDD\|227302	COG4967, PilV, Tfp pilus assembly protein PilV [Cell motility and secretion / Intracellular trafficking and secretion].	3.22301e-52
NZ_FERW01000016.1\|WP_002213852.1\|38011_38521_+\|isoprenylcysteine-carboxyl-methyltransferase-family-protein	gnl\|CDD\|224669	COG1755, COG1755, Uncharacterized protein conserved in bacteria [Function unknown].	4.4872e-74
NZ_FERW01000016.1\|WP_002235690.1\|48197_48977_+\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	1.57385e-138
NZ_FERW01000016.1\|WP_021439317.1\|39661_40249_-\|superoxide-dismutase	gnl\|CDD\|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	8.33623e-100
NZ_FERW01000016.1\|WP_042743552.1\|43440_44430_+\|PilW-family-protein	gnl\|CDD\|227301	COG4966, PilW, Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion].	6.49526e-92
NZ_FERW01000016.1\|WP_002222651.1\|46218_46671_+\|dUTP-diphosphatase	gnl\|CDD\|234802	PRK00601, dut, dUTP diphosphatase.	4.34516e-93
NZ_FERW01000016.1\|WP_002213865.1\|25113_25686_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	1.17209e-70
NZ_FERW01000016.1\|WP_042743554.1\|44994_45483_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|288394	pfam11530, Pilin_PilX, Minor type IV pilin, PilX. PilX is a protein from Neisseria meningitidis which is crucial for the formation of bacterial aggregates and adhesion to human cells. The structure of PilX is similar to all pilins as it has the common alpha/beta roll fold. PilX subunits have surface-exposed motifs which are thought to stabilize bacterial aggregates against pilus retraction. It also illustrates how a minor pilus component can modulate the virulence properties of pili which have a simple composition and structure.	1.73317e-86
NZ_FERW01000016.1\|WP_079758463.1\|26060_27971_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	1.47691e-41
NZ_FERW01000016.1\|WP_002240448.1\|33920_34994_-\|sulfate/molybdate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224043	COG1118, CysA, ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism].	9.24739e-168

>NZ_FERW01000016.1|WP_002213852.1|38011_38521_+|isoprenylcysteine-carboxyl-methyltransferase-family-protein
MTMILSILSLFFIIRLLFLAVSIKHEKALIAKGAKQYGKTNSTLLAAVHTLYYLACFVWVWLSDTAFNGISLIGTLTVMASFVILSLIIKQLGEIWTVKIYILPNHQINRSWLFKTFRHPNYFLNIIPELIGIALLCQAWYVLLIGLPIYLLVLFKRIRQEEQAMATLF
>NZ_FERW01000016.1|WP_002225363.1|37347_37680_+|hypothetical-protein
MQILSFQPDIAERMLEGTEGESVNENAQFVRTDNGYWIAWHEGVAALLAPDMPPGIPCFWVEGAESLEELCVMVERGEFDEVEEFDGDDDEWLETAQGCGHHGDACACGH
>NZ_FERW01000016.1|WP_002217475.1|36220_37057_-|sulfate-ABC-transporter-permease-subunit-CysT
MLPLKTPGVLPGFKLSLGLTVLCLSLLVVLPFAMMAAKAAEIGWGGFWNTIAEPNVLAAVWLSLRMSFYAMLTNVVFGTLVAWVLVRYEFPGKGLANALVDLPFALPTAVTGIALATLYAPNGWIGRFFEPLGIKIAFTPVGIWIALVVVSLPFIVRAVQPVLEELSGEYEEAAATLGANRFTTFRRVLLPEITPALLTGAGMMFARATGEYGSVIFIAGNIPMVSEILPLIITGKLEQFDVQGASAVALFMLLVSFVILFALNVMQWALGRRSGAKG
>NZ_FERW01000016.1|WP_002220668.1|34990_35851_-|sulfate-ABC-transporter-permease-subunit-CysW
MKPYSANPNLTEPRRLRVLLIAAALGFLLLMLVVPLVAVFYEALKGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAVLGVAMAWLLTRFDFRGKQLLTTLLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVAREIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGAVSVVSGHIRGETNTVPLLVEIFYNEYNFTGAFALSGVLALLALATLAVQNIITKLQDKKLAAAERNAV
>NZ_FERW01000016.1|WP_002240448.1|33920_34994_-|sulfate/molybdate-ABC-transporter-ATP-binding-protein
MSITIQNLNKHFGNFHALKNINLNVPTGKLVSLLGPSGCGKTTLLRIIAGLENADGGKILFDGQDVTAKHVRERKVGFVFQHYALFRHMNVFDNVAFGLTVLPKSERPSKGQIRAKVEELLKLVQLSHLAKSYPHQLSGGQRQRIALARALAVEPKLLLLDEPFGALDAKVRKELRTWLRDIHHNLGVTSILVTHDQEEALEVSDEIVVMNHGKIEQTGSAEAIYRKPENAFVTEFLGETDAFEGRIEKGFWHYNGFAWKLDAQYKWQEQTATGYIRPHEWQIAAEHETPMICAEIEKVHAVGALTHILVKHGKQDVHITLAGSDAARYPIAEGKELNLIPKQVYVFSQNELIEYSI
>NZ_FERW01000016.1|WP_002222665.1|32337_33864_+|threonine-ammonia-lyase,-biosynthetic
MNTPLPYSNYLIRILTASVYDVAVETPLEPARSLSVRLKNNILLKREDLQPVFSFKIRGAYNKMSKLPKDALACGVIAASAGNHAQGVALSAQRLGCRAVIVMPETTPKIKVDAVKSRGGEVVLRGVSYNDAYDYAMELAEKEGLTYIAPFDDPDVIAGQGTVGMEIVSQHPDPIRAVFVPIGGGGLAAGVAAFIKQVRPEIKVIGVQTNDSCCMKQSVEAGEIVHLKDVGLFSDGTAVKVVGNETFRLCKELLDEIITVDTDAVCGAVKDIFDDTRSITEPAGALALAGLKAYIAREGAENQTLIAVTSGANMNFHRLRHVSERSELGEGNEGIFAVTIPEERGSFLKFVNILGNRNITEFNYRYGDDEKAHIFVGLQAAGPQDLAVIGSRLDEAGLPNVDLTDDEIAKIHIRYMVGGRTDKVENERLVSFEFPERPGALARFLNHMQGGWNITLFHYRNHGADYGRILVGIDVPPHDAAAFDGFLESLGYSYHEETQNAAYKLFLA
>NZ_FERW01000016.1|WP_021439037.1|31020_32190_-|D-alanyl-D-alanine-carboxypeptidase
MTAHKILPVLLSIILGVSHATAASPAPNKPAVHAAPTFQTPETLTAAHIVIDLQSKQILSAKNINTPVEPAALTQLMTAYLVFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEARRLGMKNTVFKNPTGLSREGQVSTAKDLALLSEALMRDCPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTESGGYNLAVSYSGNGRHILAITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQIQIYGGSKKTVRAGFLKEAYITLPHKEAKMAEQILETIQPIPAPVKKGQVLGKIKIRQNGYTIAEKEIVALEDVEKKNWWKKLWARLTGQ
>NZ_FERW01000016.1|WP_061375311.1|28205_30857_+|DEAD/DEAH-box-helicase-family-protein
MELKFEELPYQLDAVNAVANLFAGQPNHARTFDLTSQGTGRFVGNGLDLDWETLGLNLNTVQKQNGQPETEIGAHGLNFSLEMETGTGKTYVYLRTIYELNRSYGWKKFVIVVPSVPIREGVLKSLEITKAHFDGVFGRPVMRYAEYSSSRLSDLRTFAVNDHIEILVINIQSFEKDGNVINKVNESGETPIKFIQETCPIVIIDEPQNMETEGRLNALESLNPLFTLRYSATHKQPYHKVYSLNPVQAYNLKLVKQIEVLPVLAENDVNGAFVELLEVKQAAKGRPKADLNIHYQDKKETKKKKVSVKWEDDLFEKSGGNEAYRHGFIIDGMDFDKQELAFSSGKTITRGGDGDAVRDEIMKNQIRETVREHLAKEKRLNPLGIKVLSLFFIDRVENYRTEDGTAGKFALWFEEIYRELAGNTDTAGVHDGYFSQDRKGRLKNTDGTTQADNDTYRLIMRDKETLLSFDSPLRFIFSHSALKEGWDNPNVFQICTLNETRSPLKKRQEIGRGLRIAVNQEGRRVRDENVNILTVVPNESYELFAANLQKEYEDECGIKFAAENIKNGNKKKKQLFRKDFPLDPEFQAIWDKLKYKTRYRVRFDTEELIKQASAAVAGLPEIQKPKIRIRKAQLKQSQTYGIETVEIASRSRDMETTWEIPDILGEIQKKTGLTRRTVYEIIIQSGRLKDVPGNPQRFIDLTAEVVNRSLHALMAAGIEYERTGEVYDQKLLEDMAREGIEFYENNFTFAVGNPQKTICENYIPLDSGTEQAFAQNCEDYDAKNEGGVAFYFKLPSWFKIPTPLGNYNPDWAVVKQVQDKVYFVAETKNTGKSIQAGVDAGKLRENERLKIECGERHFEALGGLAYCVVEKVGDLKLEKEEQA
>NZ_FERW01000016.1|WP_079758463.1|26060_27971_+|site-specific-DNA-methyltransferase
MIHDLENNFKQNNILKLKQLFPEVFCEDQIDFEKLKLVLGAENLAGAGERYQLDWAGKTAAYLNLQSPTSRTLVPCKEESANFDGTQNVFIEAENLEALKILQKAYAGSVKMIYIDPPYNTGSDSFIYPDKFSESRDEYARRVGDTDDAGYLKRDGVFQGAWRKNGKDSGHYHSNWLSMMLPRLHLAKTLLREDGVIFISIDDNEQAQLKLLCDEVFGAENFVNQIAVKMSELSGVKMKHLNQYAKLKEFLLIYAKNIHFANFNIEKKRKSPETLSKYLKYYSSIIENIESECEQWKIISLDEYFKDKNIILDREKLNDWKLSNAQRLVYRTNSKTVDKFLLKNPNAPDICKLINDDGKEIIKWGNKEMLFLEKYIDEYLGDIWLDISTINLNKETHTLVFENGQKPLTLIKRLLKSLETENNIVMDFFSGSGTTAHAVMQLNAEDGGNRRFICVQLPEETDEKSEARKAGFDTIAEIAKERIRRAGRQISDGLQDGSETDTGFKVFKLAESGFKQWRQPEQSDTEALQRELSLNIDSVLSETSSENLLYELMLRMGLKLTCKVSFLDDVYFVEDEDTGGLYAFLLKRVDQGLIDAVLAKHPAKVAALDRLFEGDDALKSNTVLQMKDAGVMFECV
>NZ_FERW01000016.1|WP_002213865.1|25113_25686_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MTYEIQASVREAQGTGASRRLRREGQIPGILYGEGQEPVAIAVDHKTVFYALEKESFHTALIKLSLNGETKDVIVRDFQMHPFRREVQHIDFQAVKADQLVRIRVPLHIVNAENSQAVKLQGGRVSLLNTSVEVVALPANIPAFLDLDCAEVVAGDILHLSDIKLPEGVESVSLKRNENLAVATVTGKKR
>NZ_FERW01000016.1|WP_021439317.1|39661_40249_-|superoxide-dismutase
MEHKLPQLPYEPDALSPHLSKETLEFHYGKHHQTYITNLNNQIKGTEFENLPLEEIVKKSSGGVFNNAAQTWNHTFYWLGFTSKGQGKPAGELAAAIDAKWGSFEKFQEAFNACAAGTFGSGWAWLVKTPAGGLDLVSTSNAATPLTTENTPLLTCDVWEHAYYIDYRNSRPNYLKGFWEIVNWDEVAKRFAALS
>NZ_FERW01000016.1|WP_002219448.1|40410_41817_+|replicative-DNA-helicase
MNDYTAMPSEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRIADVVSGEDFYRHEHRLIFRSIAKLINESRPADVITVQEDLQRNEELEAAGGFEYLITLAQNTPSAANIRRYAEIVRERSIMRQLAEVGTEIARSAYNPQGRDAGQLLDEAENKVFQIAESTAKSKQGFLEMPDLLKEVVQRIDMLYSRDNPDEVTGVPTGFIDLDKKTSGLQPGDLIIVAGRPSMGKTAFSINIAEHVAVEGKLPVAVFSMEMGGAQLVMRMLGSVGRLDQSVLKTGRLEDEHWGRLNEAVVKLSDAPVYIDETPGLTALELRARARRLARQFNNKLGLIVIDYLQLMAGSGRSDNRASELGEISRSLKALAKELQVPIIALSQLSRTVESRTDKRPMMSDLRESGAIEQDADLIMFMYRDEYYNQDSPMKGLAECIIGKHRNGPVGKIFLTWTGQFTKFDNAAYIPEEAKIED
>NZ_FERW01000016.1|WP_042743551.1|42125_42791_+|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTPNNKCDSGKKGQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTTDRVVWTFNQNGTFGYTKDQHLTKQSSFSYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRAVCQH
>NZ_FERW01000016.1|WP_042743559.1|42823_43444_+|type-IV-pilus-modification-protein-PilV
MKNNDCFRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKNYNLYMGNHTLSHILSAVDGDFAIDAMKTKGQLAEAQLKRFSYELKNALPDAAAIHYAVCKDSSGNAPTLSGNAFSSNCDNKANGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE
>NZ_FERW01000016.1|WP_042743552.1|43440_44430_+|PilW-family-protein
MRRKMLNVPKGSYDGMKGFTIIEFLVAGMLSMIVLMAVGSSYFTSRKLNDAANERLAIQQDLRNAATLIVRDARMAGSFGCFNMSEHIGSDVVYNVAQKNPLFSLKKGNSTNKLIPITESLNIGYPGFTQRLNALIFQYGIDDVNASADTTVVSSCAKIAKPGKKISTLQEAKSALQITNDDKQNGNITRQRHVVNAYAVGRIAGEEGLFRFQLNDDGQWGNPQLLVKKINKMDIRYIYLLVENPGIPPTNSPRYIYGCPEDDDAGKEETFKYTDKFDSSTNAVTPAGVEVLLSSGTDTKIAASSDNHIYAYRIDATIRGGNVCANRTL
>NZ_FERW01000016.1|WP_042743553.1|44408_45005_+|pilus-assembly-protein
MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGELQVLDLEYDTDSKVTFSENCAKGLCTAVNVRTNNTGNEEAFDNIVVQGKPTVEAVKRSCPANSTDLCIDKKGMEYKKGTRSVSKMPRYIIEYLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE
>NZ_FERW01000016.1|WP_042743554.1|44994_45483_+|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MMSNKMEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNISKQFILKNPLDDNQTIKSKLEIFVSGYKMNPKIAEKYNVSVYFVNKEKPRAYSLVGVPKTGTGYTLSVWMNSVGDGYKCRDAASAQAHLETLSSDVGCEAFSNRKK
>NZ_FERW01000016.1|WP_002222651.1|46218_46671_+|dUTP-diphosphatase
MNIEVEMKVLDERMADFIPAYATEGSAGLDLRACLDEEVVLQPGETFLVPTGLAIYLANPAYAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGELKVSLWNRSSEPFTVKPFERIAQMVIVPIVQARFKRVEEFVGSSRGEGGFGSTGLH
>NZ_FERW01000016.1|WP_042743457.1|46747_47935_+|succinyldiaminopimelate-transaminase
MNTLLKQLKPYPFARLHEAMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELEKYPLTAGLPELRQACANWLKRRYDGLTLNSDTEILPVLGSREALFSFVQTVLNPVSDGLKPVIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFGGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSAMSIPVQRASIAAWNDEQHVIDNRRLYQEKFEWVIPILQQVFDVKLPDASFYIWLKVPDGDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVTDVATCVKAAETIVSLYR
>NZ_FERW01000016.1|WP_002235690.1|48197_48977_+|peroxide-stress-protein-YaaA
MFFVLSPAKNLNEKDPAPVSEFTQPDLLAESDILMQQLRELAPQQIAELMHVSDKIALLNAQRNAEWHTPFTPENAKQAVFMFNGDVYEGMDANTLDIGQIRYLQNHVRLLSGLYGLLRPLDLIQPYRLEMGTAFANLRGKNLYEFWGDIITNLLNDTLAQAGSNTLVNLASQEYFKSVNTKKLRARLITPIFKDEKNGKYKIISFYAKRARGLMVRYAVEHHITDPEMLKNFNYEGYAFNDAASNESEWVFMRSEQIK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000016_1	1.1\|39353\|26\|NZ_FERW01000016\|CRISPRCasFinder	39353-39378	26	NZ_FERW01000002.1	38786-38811	0	1.0
NZ_FERW01000016_1	1.1\|39353\|26\|NZ_FERW01000016\|CRISPRCasFinder	39353-39378	26	NZ_FERW01000002.1	38264-38289	1	0.962
NZ_FERW01000016_1	1.1\|39353\|26\|NZ_FERW01000016\|CRISPRCasFinder	39353-39378	26	NZ_FERW01000022.1	18757-18782	0	1.0
NZ_FERW01000016_1	1.1\|39353\|26\|NZ_FERW01000016\|CRISPRCasFinder	39353-39378	26	NZ_FERW01000022.1	19242-19267	0	1.0
NZ_FERW01000016_1	1.1\|39353\|26\|NZ_FERW01000016\|CRISPRCasFinder	39353-39378	26	NZ_FERW01000022.1	18296-18321	1	0.962

1. spacer 1.1|39353|26|NZ_FERW01000016|CRISPRCasFinder matches to position: 38786-38811, mismatch: 0, identity: 1.0

gacgcagggttaagaaaacctacatc	CRISPR spacer
gacgcagggttaagaaaacctacatc	Protospacer
**************************

2. spacer 1.1|39353|26|NZ_FERW01000016|CRISPRCasFinder matches to position: 38264-38289, mismatch: 1, identity: 0.962

gacgcagggttaagaaaacctacatc	CRISPR spacer
gacgcagggttaagaaaacctgcatc	Protospacer
*********************.****

3. spacer 1.1|39353|26|NZ_FERW01000016|CRISPRCasFinder matches to position: 18757-18782, mismatch: 0, identity: 1.0

gacgcagggttaagaaaacctacatc	CRISPR spacer
gacgcagggttaagaaaacctacatc	Protospacer
**************************

4. spacer 1.1|39353|26|NZ_FERW01000016|CRISPRCasFinder matches to position: 19242-19267, mismatch: 0, identity: 1.0

gacgcagggttaagaaaacctacatc	CRISPR spacer
gacgcagggttaagaaaacctacatc	Protospacer
**************************

5. spacer 1.1|39353|26|NZ_FERW01000016|CRISPRCasFinder matches to position: 18296-18321, mismatch: 1, identity: 0.962

gacgcagggttaagaaaacctacatc	CRISPR spacer
gacgcaaggttaagaaaacctacatc	Protospacer
******.*******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_FERW01000004

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4200 : 16011

Haemophilus_phage(46.15%)

plate,terminase,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002223797.1\|4200_4707_+	DUF1804 family protein	I6PBD1	Pseudomonas_phage	1.4e-40	51.2
WP_002229455.1\|4703_5216_-	hypothetical protein	A0A1C6ZDM2	Pseudomonas_phage	1.2e-26	37.7
WP_079255425.1\|5299_6850_+\|terminase	phage terminase large subunit	B7SDN0	Haemophilus_phage	1.1e-218	70.8
WP_002219310.1\|6849_8418_+	DUF935 domain-containing protein	A0A0M3LRU4	Mannheimia_phage	1.0e-187	61.4
WP_002219309.1\|8404_9730_+\|head	phage head morphogenesis protein	B7SDN5	Haemophilus_phage	8.5e-114	50.1
WP_002213608.1\|9857_10274_+	phage virion morphogenesis protein	B7SDN8	Haemophilus_phage	2.4e-30	48.2
WP_002219308.1\|10504_11566_+	hypothetical protein	A0A2D1GNS3	Pseudomonas_phage	1.9e-60	44.1
WP_002219307.1\|11666_12137_+	hypothetical protein	F6MIL2	Haemophilus_phage	5.6e-20	38.2
WP_002219306.1\|12126_13272_+	hypothetical protein	F6MIL3	Haemophilus_phage	3.9e-115	57.9
WP_002219305.1\|13268_13937_+\|plate	phage baseplate assembly protein V	A0A0M3LPA3	Mannheimia_phage	5.1e-59	51.6
WP_002219304.1\|14037_14385_+	hypothetical protein	A0A0M3LQK5	Mannheimia_phage	2.8e-32	60.3
WP_002219303.1\|14398_15454_+\|plate	baseplate J/gp47 family protein	A0A0M3LQN4	Mannheimia_phage	1.1e-100	56.1
WP_002213590.1\|15450_16011_+	YmfQ family protein	F6MIL7	Haemophilus_phage	1.0e-28	38.3

DBSCAN-SWA_2

69905 : 77881

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213525.1\|69905_70853_-	paraslipin	M1PGF9	Moumouvirus	1.0e-20	30.2
WP_002219255.1\|70867_71275_-	NfeD family protein	NA	NA	NA	NA
WP_002219254.1\|71355_72015_+	uracil-DNA glycosylase	A0A0A7D988	Equid_alphaherpesvirus	1.2e-55	49.3
WP_025458549.1\|72055_72574_+	SAM-dependent DNA methyltransferase	A0A2H4PQP4	Staphylococcus_phage	1.7e-06	36.8
WP_118829631.1\|72435_72843_+	N-6 DNA methylase	A0A2H4PQP4	Staphylococcus_phage	1.0e-09	47.7
WP_002232471.1\|72646_73120_+	N-6 DNA methylase	A0A2H4PQP4	Staphylococcus_phage	4.3e-20	39.7
WP_002236995.1\|73467_74412_+	hypothetical protein	NA	NA	NA	NA
WP_079254874.1\|74553_74688_+	DUF45 domain-containing protein	NA	NA	NA	NA
WP_002219251.1\|74977_75493_-	hypothetical protein	NA	NA	NA	NA
WP_096110586.1\|75681_75933_-	hypothetical protein	NA	NA	NA	NA
WP_002223760.1\|75958_77881_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.7e-68	31.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_FERW01000040

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

8. NZ_FERW01000002

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

9. NZ_FERW01000050

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

10. NZ_FERW01000022

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

11. NZ_FERW01000001

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

127469 : 136680

Burkholderia_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002219184.1\|127469_129749_+	ribonucleoside-diphosphate reductase subunit alpha	I3UMG3	Colwellia_phage	2.4e-310	67.9
WP_002222381.1\|129806_130820_+	DNA (cytosine-5-)-methyltransferase	E5E3X6	Burkholderia_phage	8.0e-88	52.8
WP_002213380.1\|130812_132000_+	type II restriction enzyme	E5E3X4	Burkholderia_phage	6.6e-33	38.9
WP_002217076.1\|132060_133194_+	ribonucleotide-diphosphate reductase subunit beta	W6AT53	Erwinia_phage	2.4e-165	74.8
WP_002217077.1\|133428_133719_+	2Fe-2S ferredoxin-like protein	G9IAA2	Pseudomonas_phage	7.5e-15	54.5
WP_002213385.1\|133759_134038_-	cell division protein FtsB	NA	NA	NA	NA
WP_002223714.1\|134051_135338_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	3.9e-148	62.5
WP_002223715.1\|135382_135823_-	DUF4149 domain-containing protein	NA	NA	NA	NA
WP_002223716.1\|135837_136680_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.1e-47	42.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

12. NZ_FERW01000017

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

13. NZ_FERW01000025

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CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000025_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000025_1

6018-6123

Orphan

Consensus_repeat	Method
CGAAGGCAAATGCGGCGAGGGCAAATGCGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000025_1

>merge|NZ_FERW01000025|1|6018-6123|CRISPRCasFinder
CGAAGGCAAATGCGGCGAGGGCAAATGCGGTGCGACCGTAAAAAAAACCCACAAACACACCAAAGCATCTAAAGCCAAGGCCAAATCTGCCGAAGGCAAATGCGGC

>NZ_FERW01000025|1|1|6018-6123|CRISPRCasFinder
CGAAGGCAAATGCGGCGAGGGCAAATGCGGT	GCGACCGTAAAAAAAACCCACAAACACACCAAAGCATCTAAAGC
CAAGGCCAAATCTGCCGAAGGCAAATGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000025.1\|WP_002224203.1\|4080_4974_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132844
NZ_FERW01000025.1\|WP_002224202.1\|2874_3978_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_FERW01000025.1\|WP_002221734.1\|507_1965_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|273342
NZ_FERW01000025.1\|WP_002220005.1\|7094_7841_+\|DUF2063-domain-containing-protein	unknown	unknown	gnl\|CDD\|225760
NZ_FERW01000025.1\|WP_002220007.1\|7862_8450_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171564
NZ_FERW01000025.1\|WP_002220009.1\|8893_9316_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000025.1\|WP_002220010.1\|10339_11347_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_FERW01000025.1\|WP_101030691.1\|8754_8865_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000025.1\|WP_002218249.1\|6262_7105_+\|DUF692-family-protein	unknown	unknown	gnl\|CDD\|225761
NZ_FERW01000025.1\|WP_002218247.1\|5315_5765_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_FERW01000025.1\|WP_123810359.1\|9634_9856_-\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000025.1\|WP_002215152.1\|8455_8635_+\|zf-HC2-domain-containing-protein	unknown	unknown	gnl\|CDD\|379219
NZ_FERW01000025.1\|WP_002220011.1\|11492_12095_-\|L-threonylcarbamoyladenylate-synthase	unknown	unknown	gnl\|CDD\|223088
NZ_FERW01000025.1\|WP_002224204.1\|12128_13400_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856

Protein	Function_ID	Function_description	E-value
NZ_FERW01000025.1\|WP_002224203.1\|4080_4974_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132844	cd07205, Pat_PNPLA6_PNPLA7_NTE1_like, Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1. Patatin-like phospholipase domain containing protein 6 (PNPLA6) and protein 7 (PNPLA7) are included in this family. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. PNPLA7 is an insulin-regulated phospholipase that is homologus to Neuropathy Target Esterase (NTE or PNPLA6) and is also known as NTE-related esterase (NRE). Human NRE is predominantly expressed in prostate, white adipose, and pancreatic tissue. NRE hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid, but shows no lipase activity with substrates like triacylglycerols (TG), cholesteryl esters, retinyl esters (RE), phosphatidylcholine (PC), or monoacylglycerol (MG). This family includes subfamily of PNPLA6 (NTE) and PNPLA7 (NRE)-like phospholipases.	9.76013e-63
NZ_FERW01000025.1\|WP_002224202.1\|2874_3978_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_FERW01000025.1\|WP_002220010.1\|10339_11347_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	9.57829e-64
NZ_FERW01000025.1\|WP_002218249.1\|6262_7105_+\|DUF692-family-protein	gnl\|CDD\|225761	COG3220, COG3220, Uncharacterized protein conserved in bacteria [Function unknown].	6.09039e-151
NZ_FERW01000025.1\|WP_002218247.1\|5315_5765_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	3.78246e-27
NZ_FERW01000025.1\|WP_002221734.1\|507_1965_+\|MFS-transporter	gnl\|CDD\|273342	TIGR00924, putative_Di/Tri_peptide_transporter, amino acid/peptide transporter (Peptide:H+ symporter), bacterial. The model describes proton-dependent oligopeptide transporters in bacteria. This model is restricted in its range in recognizing bacterial proton-dependent oligopeptide transporters, although they are found in yeast, plants and animals. They function by proton symport in a 1:1 stoichiometry, which is variable in different species. All of them are predicted to contain 12 transmembrane domains, for which limited experimental evidence exists. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_FERW01000025.1\|WP_002220005.1\|7094_7841_+\|DUF2063-domain-containing-protein	gnl\|CDD\|225760	COG3219, COG3219, Uncharacterized protein conserved in bacteria [Function unknown].	5.3181e-115
NZ_FERW01000025.1\|WP_002215152.1\|8455_8635_+\|zf-HC2-domain-containing-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	0.000444788
NZ_FERW01000025.1\|WP_002220007.1\|7862_8450_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171564	PRK12532, PRK12532, RNA polymerase sigma factor; Provisional.	1.33136e-125
NZ_FERW01000025.1\|WP_002220011.1\|11492_12095_-\|L-threonylcarbamoyladenylate-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	1.68071e-60
NZ_FERW01000025.1\|WP_002224204.1\|12128_13400_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0

>NZ_FERW01000025.1|WP_002218247.1|5315_5765_+|DoxX-family-protein
MKIGTTWQTASAMLVLRLFAAYEFLESGLQKWNGENWFSEINDQFPFPFNLLPDALNWNLAMYAELLLPVLLLLGLATRLSALGLMVVTAVAWAAVHAGSGYNVCDNGYKMALIYIVVLIPLLFQGAGGWSLDTLLKKRFCPQCRLKQD
>NZ_FERW01000025.1|WP_002224203.1|4080_4974_-|patatin-like-phospholipase-family-protein
MVTFSKIRPLLAIAAAALLAACGTAGNNAARKPVQTAKPAAVVGLALGGGASKGFAHVGIIKVLKENGIPVKVVTGTSAGSIVGSLFASGMSPDRLELEAEILGKTDLVDLTLSTSGFIKGEKLQNYINRKVGGRRIQQFPIKFAAVATDFETGKAVAFNQGNAGQAVRASAAIPNVFQPVIIGRHTYVDGGLSQPVPVSAARRQGANFVIAVDISARPGKNISQGFFSYFDQTLNVMSVSALQNELGQADVVIKPQVLDLGAVGGFDQKKRAIRLGEEAARAALPEIKRKLAAYRY
>NZ_FERW01000025.1|WP_002224202.1|2874_3978_-|peptide-chain-release-factor-2
MEAEVINQLNNTLNDLEKRSEDIRVYMDYQGKKDRLEEVVGLSEDPELWNDPKRAQEIGKERKILEGIVLTLDNIATGIEDNRMLIEMTVEENDEEGFAAVQEDVAGLEKQMADLEFKRMFNQPADPNNCFIDITAGAGGTEAEDWAGMLFRMYSRYAERKGFKIEILEEDDGEIAGINRATIRVEGEYAYGLLRTETGVHRLVRYSPFDSNNKRHTSFASVFVYPEIDDSIEIEINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGIVVQCQNDRSQHANKAAAMEMLKSKLYELEMRKRNEEKQALEEGKSDVGWGSQIRSYVLDSSRIKDLRTGYEVGNTKAVLDGDLDGFIEASLKQGV
>NZ_FERW01000025.1|WP_002221734.1|507_1965_+|MFS-transporter
MSRHPAPTGEKTFFGHPFQLSTLFHIELWERFSFYGMQGILLIYLYYTADKGGLGIDKTLAGGIVGAYSGSVYLSTILGAWFADRVWGAEKTLFLSGIVVMLGHIVLAAAPGLYGLLIGLIFIALGSGGVKSTASSMVGALYEQDEMRPLRDAGFSIFYIAINIGGFLGPLLTGLLQENIGFHYGFGAAAVGMAFGLWRYSLGRKNLPHPTVPHPLSKGQGKTAAAVGITLIAALATAIKTGLVNLDNFSGILLSTVILAVIAYFARLLTNPRVSSDNKRHIIAYIPLFLTICMFWAVWFQIYTVATVYFDETVNRTIGSFTVPVAWKDSMQSLWVILFSGLMAAMWTKMGRKQPKTPLKFAMAVFVTGASFLGFIPFISAGTPMPIAVFALIVLAITIGELMISPIALSISTKIAPPLFKTQMVALNFLAFSLGFTLGGVLFEKCYQAGDEIGFYRLLFYIGAATGFLLLLLVPKLNKMLEGTD
>NZ_FERW01000025.1|WP_002218249.1|6262_7105_+|DUF692-family-protein
MIQHAGLGYRRDLAEDFLSLSENSPICFIEAAPENWLKMGGWARKQFDRVAERLPLALHGLSMSLGGQAPLDTDLIDGIKEMMRRYDCTFFSDHLSYCHDGGHLYDLLPLPFTEEMVHHTARRIREVQDRLGCRIAVENTSYYLHSPLAEMNEVEFLNAVAREADCGIHLDVNNIYVNAVNHGLLSPEAFLKNVDADRVCYIHIAGHDVETPELLIDTHGAAVLPTVWDLLELAYAKLPTIPPTLLERDFNFPPFAELEAEVAKIADYQTRAGKECRRAA
>NZ_FERW01000025.1|WP_002220005.1|7094_7841_+|DUF2063-domain-containing-protein
MQPETSAQYQHRFAQAIRGGEAADGLPQDRLNVYIRLIRNNIHSFIDRCYTETRQYFDSEEWSRLKEGFVRDAHAQTPYFQEIPGEFLQYCQSLPLSDGILALMDFEYTQLLAEVAQIPDIPDIHYSNHSKYTPSPAAFIRQYRYDVTDDLQEAETALLIWRNAEDDVMYQTLDGFDMMLLEIMGSSALSFDTLAQTLVEFMPEDDNWKNILLGKWSGWTEQRIIIPSLSAISENMEGNSPGQNHLSA
>NZ_FERW01000025.1|WP_002220007.1|7862_8450_+|sigma-70-family-RNA-polymerase-sigma-factor
MPLPDLTDAELIESRKLLLHFARLQLPDHPDLAEDLVQETLLSAYSAGDSFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTTLDDELLDEAFESHFSQNGHWTQEGQPQHWNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRARESLRQCLQIKWFNQENPK
>NZ_FERW01000025.1|WP_002215152.1|8455_8635_+|zf-HC2-domain-containing-protein
MKKCRDIALLLSKHQDRETTPGEKISIYTHLLFCPYCREYKRQLQTIKRSLAKTTRTSK
>NZ_FERW01000025.1|WP_101030691.1|8754_8865_+|hypothetical-protein
MYKYAKYEGCINLPYLLYLPYFTDDTPPPAQPVLSE
>NZ_FERW01000025.1|WP_002220009.1|8893_9316_+|hypothetical-protein
MRPIFLSFVLLPILITACSTPDKSARWENIGTISNGNIHTYINKDSVRKNGNLMIFQDKKVVTNLKQERFANTPAYKTAIAEWEIHCNNKTYRLSSLQLFDTKNTEISTQSYTASSLRPMSILSGTLTEKQYETVCGKKL
>NZ_FERW01000025.1|WP_123810359.1|9634_9856_-|hypothetical-protein
MPYYLYCLRLRRLVLIFVNPLYECIGVKTSDYFLEAVLVTGRSRECKKCFIKIMGASSFVYQWNNLRLDSEIV
>NZ_FERW01000025.1|WP_002220010.1|10339_11347_+|IS5-family-transposase
MSTFFRQTAQAMIAKHIDRFPLLKLEQVIDWQPIEHYLNRQKTRYLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYSTLCRYRNWLAQDDTLSELLKLINRQLTEKGLKIEKASAAVIDATIIQTAGSKQRQAIEVDEEGQVSGQTTPSKDKDARWTKKNGLYRLGYKQHTRTDEEGYIKKLHITPANAHECKHLSPLLEGLPKGTTVYADKGYDSAENRQHLEEHQLLDGIMRKACRNRPLSETQTKRNRYLSKTRYVVEQSFGTLHRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPAAA
>NZ_FERW01000025.1|WP_002220011.1|11492_12095_-|L-threonylcarbamoyladenylate-synthase
MTDMLQTAFYIMLFPRIIAASAQRKLSVYLKKGGLVAYPTESCYGLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQFEQLQPLLQMPSENLQDMLRKEWPAPKTFLLSAKSCVLPELRGKQRSKLAVRVPAHVGARRLCQALQTPLVSTSCNRAGKRACRTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGETGKRLR
>NZ_FERW01000025.1|WP_002224204.1|12128_13400_-|phosphoribosylamine--glycine-ligase
MKLLVIGNGGREHALAWKLAQSPKVETVFVAPGNAGTAIEPKLQNIDLTAHQDLIEFCRKENIVFTVVGPEAPLAAGVVDDFRAAGLKIFGPTQYAAQLESSKDFAKAFMAKYNIPTAQYQTFENADAAHDYVNQKGAPIVIKADGLAAGKGVIVAMTLDEAHAAIDDMLLDNKMGNAGARVVIEDFLQGEEASFIVMVDGNNVLPMATSQDHKRLLDGDKGLNTGGMGAYSPAPVVTPVVYERAMNEIILPTVAGMKAEGHEFTGFLYAGLMIDQSGAPYTIEFNCRFGDPETQPIMSRLNSDLADLVEAAIDGKLDSVAAEWNPQTAVGVVLAAQNYPETPKKGDVISGLDAANQVGKVFHAGTTANEKGDVLTNGGRVLCVVGLGDNVAQAKAKAYGALEKISFDGMQYRKDIADKAINR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

14. NZ_FERW01000008

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000008_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000008_1

60644-60745

Orphan

I-E

Consensus_repeat	Method
AAGGTCTAGATTCCCGCCTGAGCGGGAATGACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000008_1

>merge|NZ_FERW01000008|1|60644-60745|CRISPRCasFinder
AAGGTCTAGATTCCCGCCTGAGCGGGAATGACGGGTCTTTTATAAACTTTGAATATTGCTGTTATCCCAAGGTCTAGATTCCCGCCTGCGCGGGAATGACGG

>NZ_FERW01000008|1|1|60644-60745|CRISPRCasFinder
AAGGTCTAGATTCCCGCCTGAGCGGGAATGACGG	GTCTTTTATAAACTTTGAATATTGCTGTTATCCC
AAGGTCTAGATTCCCGCCTGCGCGGGAATGACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000008.1\|WP_002215243.1\|69839_70688_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NZ_FERW01000008.1\|WP_002235330.1\|70781_71783_-\|thiamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|130321
NZ_FERW01000008.1\|WP_002233362.1\|53314_53722_-\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000008.1\|WP_002221794.1\|69328_69814_-\|CinA-family-protein	unknown	unknown	gnl\|CDD\|334938
NZ_FERW01000008.1\|WP_002214937.1\|45191_45641_-\|type-IV-pilin-protein	unknown	unknown	gnl\|CDD\|227303
NZ_FERW01000008.1\|WP_002235606.1\|52474_53266_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NZ_FERW01000008.1\|WP_002224146.1\|45728_46028_-\|competence-protein-ComE	unknown	unknown	gnl\|CDD\|213597
NZ_FERW01000008.1\|WP_002224145.1\|44437_44650_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000008.1\|WP_042743324.1\|71841_72522_+\|pyrimidine-5'-nucleotidase	unknown	unknown	gnl\|CDD\|273917
NZ_FERW01000008.1\|WP_002218483.1\|55733_56960_+\|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl\|CDD\|227341
NZ_FERW01000008.1\|WP_002218487.1\|54527_55571_+\|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|225364
NZ_FERW01000008.1\|WP_002216166.1\|65383_65668_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NZ_FERW01000008.1\|WP_042743328.1\|57245_59396_+\|TIGR01666-family-membrane-protein	unknown	unknown	gnl\|CDD\|130727
NZ_FERW01000008.1\|WP_002221799.1\|53721_54408_-\|YggS-family-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|143497
NZ_FERW01000008.1\|WP_002237405.1\|72547_72820_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000008.1\|WP_042743325.1\|67658_69227_+\|bifunctional-peptide-methionine-(S)-S-oxide-reductase-MsrA/peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_FERW01000008.1\|WP_042743326.1\|66247_67513_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_FERW01000008.1\|WP_153317777.1\|63995_64154_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000008.1\|WP_061727187.1\|60907_63904_-\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|225953
NZ_FERW01000008.1\|WP_002231430.1\|51911_52328_-\|RNA-polymerase-binding-protein-DksA	unknown	unknown	gnl\|CDD\|274124

Protein	Function_ID	Function_description	E-value
NZ_FERW01000008.1\|WP_002215243.1\|69839_70688_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	3.47239e-50
NZ_FERW01000008.1\|WP_002235330.1\|70781_71783_-\|thiamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|130321	TIGR01254, Thiamine-binding_periplasmic_protein, ABC transporter periplasmic binding protein, thiB subfamily. The model describes thiamine ABC transporter, periplasmic protein in bacteria and archae. The protein belongs to the larger ABC transport system. It consists of at least three components: the thiamine binding periplasmic protein; an inner membrane permease; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). [Transport and binding proteins, Other].	2.51981e-150
NZ_FERW01000008.1\|WP_002218483.1\|55733_56960_+\|PilT/PilU-family-type-4a-pilus-ATPase	gnl\|CDD\|227341	COG5008, PilU, Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_FERW01000008.1\|WP_002214937.1\|45191_45641_-\|type-IV-pilin-protein	gnl\|CDD\|227303	COG4968, PilE, Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion].	3.69193e-59
NZ_FERW01000008.1\|WP_002235606.1\|52474_53266_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.74321e-99
NZ_FERW01000008.1\|WP_002224146.1\|45728_46028_-\|competence-protein-ComE	gnl\|CDD\|213597	TIGR01259, ComE_operon_protein_1, comEA protein. This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation].	5.77181e-38
NZ_FERW01000008.1\|WP_042743324.1\|71841_72522_+\|pyrimidine-5'-nucleotidase	gnl\|CDD\|273917	TIGR01993, Suppressor_of_disruption_of_TFIIS, pyrimidine 5'-nucleotidase. This family of proteins includes the SDT1/SSM1 gene from yeast which has been shown to code for a pyrimidine (UMP/CMP) 5'nucleotidase. The family spans plants, fungi and a small number of bacteria. These enzymes are members of the haloacid dehalogenase (HAD) superfamily of hydrolases, specifically the IA subfamily (variant 3, TIGR01509).	3.39834e-84
NZ_FERW01000008.1\|WP_002221799.1\|53721_54408_-\|YggS-family-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|143497	cd06824, PLPDE_III_Yggs_like, Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins. This subfamily contains mainly uncharacterized proteobacterial proteins with similarity to the hypothetical Escherichia coli protein YggS, a homolog of yeast YBL036c, which is homologous to a Pseudomonas aeruginosa gene that is co-transcribed with a known proline biosynthetic gene. Like yeast YBL036c, Yggs is a single domain monomeric protein with a typical TIM-barrel fold. Its structure, which shows a covalently-bound PLP cofactor, is similar to the N-terminal domain of the fold type III PLP-dependent enzymes, bacterial alanine racemase and eukaryotic ornithine decarboxylase, which are two-domain dimeric proteins. YggS has not been characterized extensively and its biological function is still unkonwn.	9.55397e-130
NZ_FERW01000008.1\|WP_002218487.1\|54527_55571_+\|type-IV-pilus-twitching-motility-protein-PilT	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_FERW01000008.1\|WP_042743328.1\|57245_59396_+\|TIGR01666-family-membrane-protein	gnl\|CDD\|130727	TIGR01666, Uncharacterized_protein_HI_1680, TIGR01666 family membrane protein. This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other].	0
NZ_FERW01000008.1\|WP_002216166.1\|65383_65668_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	9.46959e-53
NZ_FERW01000008.1\|WP_002221794.1\|69328_69814_-\|CinA-family-protein	gnl\|CDD\|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	1.30611e-68
NZ_FERW01000008.1\|WP_042743326.1\|66247_67513_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	5.305e-175
NZ_FERW01000008.1\|WP_042743325.1\|67658_69227_+\|bifunctional-peptide-methionine-(S)-S-oxide-reductase-MsrA/peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	0
NZ_FERW01000008.1\|WP_061727187.1\|60907_63904_-\|pilus-assembly-protein	gnl\|CDD\|225953	COG3419, PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 [Cell motility and secretion / Intracellular trafficking and secretion].	1.58343e-169
NZ_FERW01000008.1\|WP_002231430.1\|51911_52328_-\|RNA-polymerase-binding-protein-DksA	gnl\|CDD\|274124	TIGR02420, RNA_polymerase-binding_transcription_factor_DksA, RNA polymerase-binding protein DksA. The model that is the basis for this family describes a small, pleiotropic protein, DksA (DnaK suppressor A), originally named as a multicopy suppressor of temperature sensitivity of dnaKJ mutants. DksA mutants are defective in quorum sensing, virulence, etc. DksA is now understood to bind RNA polymerase directly and modulate its response to small molecules to control the level of transcription of rRNA. Nearly all members of this family are in the Proteobacteria. Whether the closest homologs outside the Proteobacteria function equivalently is unknown. The low value set for the noise cutoff allows identification of possible DksA proteins from outside the proteobacteria. TIGR02419 describes a closely related family of short sequences usually found in prophage regions of proteobacterial genomes or in known phage. [Transcription, Transcription factors, Regulatory functions, Small molecule interactions].	1.10262e-48

>NZ_FERW01000008.1|WP_042743328.1|57245_59396_+|TIGR01666-family-membrane-protein
MKTPLLKPLLITSLPVFASVFTAASIVWQLGEPKLAMPFVLGIIAGGLVDLDNRLTGRLKNIIATVALFTLSSLTAQSTLGTGLPFILAMTLMTFGFTILGAVGLKYRTFAFGALAVATYTTLTYTPETYWLTNPFMILCGTVLYSTAILLFQIILPHRPVQESVANAYDALGGYLEAKADFFDPDEAEWIGNRHIDLAMSNTGVITAFNQCRSALFYRLRGKHRHPRTAKMLRYYFAAQDIHERISSAHVDYQEMSEKFKNTDIIFRIHRLLEMQGQACRNTAQALRASKDYVYSKRLGRAIEGCRQSLRLLSDSNDSPDIRHLRRLLDNLGSVDQQFRQLQHNGLQAENDRMGDTRIAALETGSLKNTWQAIRPQLNLESGVFRHAVRLSLVVAAACTIVEALNLNLGYWILLTALFVCQPNYTATKSRVRQRIAGTVLGVIVGSLVPYFTPSVETKLWIVIASTTLFFMTRTYKYSFSTFFITIQALTSLSLAGLDVYAAMPVRIIDTIIGASLAWAAVSYLWPDWKYLTLERTAALAVCSNGAYLEKITERLKSGETGDDVEYRATRRRAHEHTAALSSTLSDMSSEPAKFADSLQPGFTLLKTGYALTGYISALGAYRSEMHEECSPDFTAQFHLAAEHTAHIFQHLPETEPDDFQTALNTLRGELDTLRTHSSGTQSHILLQQLQLIARQLEPYYRAYRQIPHRQPQNAA
>NZ_FERW01000008.1|WP_002218483.1|55733_56960_+|PilT/PilU-family-type-4a-pilus-ATPase
MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTGEETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRGLLIIVGPTGSGKSTTMATMLEHRNKTLPSHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGEVRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLLINTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDRVNGLNLIS
>NZ_FERW01000008.1|WP_002218487.1|54527_55571_+|type-IV-pilus-twitching-motility-protein-PilT
MQITDLLAFGAKNKASDLHLSSGISPMIRVHGDMRRINLPEMSAEEVGNMVTSVMNDHQRKIYQQNLEVDFSFELPNVARFRVNAFNIGRGPAAVFRTIPSTVLSLEELKAPSIFQKIAESPRGMVLVTGPTGSGKSTTLAAMINYINETQPAHILTIEDPIEFVHQSKKSLINQRELHQHTLSFANALRSALREDPDVILVGEMRDPETIGLALTAAETGHLVFGTLHTTGAAKTVDRIVDVFPAGEKEMVRSMLSESLTAVISQNLLKTHDGNGRVASHEILIANPAVRNLIRENKITQINSVLQTGQASGMQTMDQSLQSLVRQGLIAPEVARRRAQNSESMSF
>NZ_FERW01000008.1|WP_002221799.1|53721_54408_-|YggS-family-pyridoxal-phosphate-dependent-enzyme
MTVLQERYCEVSDRIGKLVLQAGRKPHSVSLIAVGKTFPSDGIREVYAAGQRDFGENYIQEWYGKTEELADLTDIVWHVIGDVQSNKTKFVAERAHWVHTVCRLKTAVRLSGQRPSSMPPLQVCIEVNIAGEAVKHGVAPEEAVALAVEVAKLPNIVVRGLMCVAKANSSETELKVQFQTMRKLLADLNTAGVKADVLSMGMSDDMPAAIECGATHVRIGSAIFGKRG
>NZ_FERW01000008.1|WP_002233362.1|53314_53722_-|hypothetical-protein
MEIRAIKYTAMAALLAFTVAGCQLAGWYECSSLSGWCKLRKPAAIDFWDIGGESPPSLEDYEIPLLDGNRSVRANEYESAQQSYFYRKIGKFEACGLDWRTRDGKPLIETFKQEGFDCLKKQGLRRNGLSERVRW
>NZ_FERW01000008.1|WP_002235606.1|52474_53266_-|pyrroline-5-carboxylate-reductase
MNVYFLGGGNMAAAVAGGLVKQGGYRIHIANRGAEKRERLQKELGVETSETLPELHSDDVLILAVKPQDMEAACKNIRTNGALVLSVAAGLPVDTLSRYIGGTRRIVRVMPNTPGKIGLGVSGMFAEAEVSETDRRIADRIMKSVGLTVWLDDEEKMHGITGISGSGPAYVFYLLDALQNAAIRQGFDMAEARALSLATFKGAVALAEQTGEDFEKLQKNVTSKGGTTHEAVEAFRRHRVAEAISEGVCACVRRSQEMERQYQ
>NZ_FERW01000008.1|WP_002231430.1|51911_52328_-|RNA-polymerase-binding-protein-DksA
MAKLTEQDILNWNGPEDDYMNDEHLAFFRELLVKMQDELIENASATTGHLQEHESAPDPADRATQEEEYALELRTRDRERKLLSKIQATIRNIDEGDYGFCADTGEPIGLKRLLARPTATLSVESQERRERMKKQFAD
>NZ_FERW01000008.1|WP_002224146.1|45728_46028_-|competence-protein-ComE
MKKMFVLFCMLFSCAFSLAAVNINAASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
>NZ_FERW01000008.1|WP_002214937.1|45191_45641_-|type-IV-pilin-protein
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEGFCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
>NZ_FERW01000008.1|WP_002224145.1|44437_44650_+|hypothetical-protein
MPHIHPLHLFPPHIAERGLLYFQQGKVGAVQKTSTGRYRAEVCGLENYWVWLKLDSDLYIKDESCDCPYV
>NZ_FERW01000008.1|WP_061727187.1|60907_63904_-|pilus-assembly-protein
MNSQKLPEVKNGNYQGKNRQVTFNAYFQGTKKNSIFSFDNTDEVVAQKGGTVVFGAATYLPPYGKVSGFDADKLQERGNAVGWIGTIHPGLVGYSYQGSTCNSRDCPELSYKTQFIFSDQGLKNKVNGKLDIDADKSRDNSPIYKLPDHPWLGVSFNLSSESTNESKQLKKLVSSFSENVTQNNSTQSPYTDINLVYTTDKHRNNGNIGRGDNHAVAFYLNAKLHLLAKKQIKGISKDQTINLGTLKTRIKPSDAWKNKRHHVSNVNNWTFEDKGSVSVKLKLPEVKAGRCINKPNPNPNKKDLSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSRIFLQNLKRKTDTSRPGRYSLADLAKSDIENRQPNFTGRQTVIRLDGGVHEIKLQGNEVANFNGNDGKNDTFGIIREGSFMPDDSEWKKVLLPWTVRGFSNDNEFVKFNKEEKNNDNKPKYSQKYRSRDNNNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIESQDSTLAKELRAFAEKGYVGDRYGVDGGFVLRQVERNGKDHVFMFGAMGLGGRGAYALDLTKADGNDPTKASLFDVKDNGNNGNNRVKLGYTVGTPQIGKTHNDKYAAFLASGYATKDVNSNDNTTALYVYDLESSGTLIKKIEVPNGKGGLSSPTLVDKDLDGTVDIAYAGDRGGSMYRFDLSSQDPKQWSARAIFKGDKPITSAPAISQLKDKRVVIFGTGSDLSEDDVLSTSEQYIYGIFDDDTATTGSVNFSGLGGGLLEQELKQEGKTLFLTDYKRSDGSGNKGWVVKLKDGQRVTVKPTVVLRTAFVTIHKYTGTDKCGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKKTSSGKSIPIGCMEKDNGIACPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPDGKRAGKNNRCFSQKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY
>NZ_FERW01000008.1|WP_153317777.1|63995_64154_+|hypothetical-protein
MAENLPFPSFIHLLFLEFAFTGRGGAPRTPGFGKPPDSAPAELLVEKLTSPF
>NZ_FERW01000008.1|WP_002216166.1|65383_65668_-|GIY-YIG-nuclease-family-protein
MQPAVYILASQRNGTLYIGVTSDLVQRIYQHREHLIEGFTSRYNVTMLVWYELHPTMESAITREKQLKKWNRAWKLQLIEENNVSWQDLWFDII
>NZ_FERW01000008.1|WP_042743326.1|66247_67513_-|signal-recognition-particle-docking-protein-FtsY
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEEVESLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAEEAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELETVLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDARAFVDALLD
>NZ_FERW01000008.1|WP_042743325.1|67658_69227_+|bifunctional-peptide-methionine-(S)-S-oxide-reductase-MsrA/peptide-methionine-(R)-S-oxide-reductase-MsrB
MKHRTFFSLCAKFGCLLALGACSPKIVDAGAATVPHTLSTLKTADNRPASVYLKKDKPTLIKFWASWCPLCLSELGQTEKWAQDAKFSSANLITVASPGFLHEKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVYPSWALIGKDGDVQRIVKGSINEAQALALIRDPNADLGSLKHSFYKPDTQKKDSKIMNTRIIYLAGGCFWGLEAYFQRIDGVVDAVSGYANGNTKNPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYFFRVVDPTSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAEEYHQDYLIKNPNGYCHIDIRKADEPLPGKTKTAPQGKGFDAATYKKPSDAELKRTLTEEQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPIDAKSVTEHDDFSYNMRRTEVRSHAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQMDAAGYGALKSKVK
>NZ_FERW01000008.1|WP_002221794.1|69328_69814_-|CinA-family-protein
MDALHTIARNLTKKRQTVSCAESCTGGLLAAVFTSVAGSSQWFDQSFVTYSNKAKEDRLGVLPETLLEHGAVSRQTVYEMARGAKAVAQADYAVGISGIAGPGGGSESKPVGTVWFGFAFPGGSCEAMRRFDGNRESVRAQAVAFALERLAGLIENGGDAV
>NZ_FERW01000008.1|WP_002215243.1|69839_70688_-|mechanosensitive-ion-channel-family-protein
MDFKQFDFLHLISVSGWEHLAEKAWAFGLNLAAALLIFLVGKWAAKRIVAVMRAAMTRAQVDATLISFLCNVANIGLLILVIIAALGRLGVSTTSVTALIGGAGLAVALSLKDQLSNFAAGALIILFRPFKVGDFIRVGGFEGYVREIKMVQTSLRTTDNEEVVLPNSVVMGNSIVNRSTLPLCRAQVIVGVDYNCDLKVAKEAVLKAAVEHPLSVQNEERQAAAYITALGDNAIEITLWAWANEADRWTLQCDLNEQVVENLRKVNINIPFPQRDIHIINS
>NZ_FERW01000008.1|WP_002235330.1|70781_71783_-|thiamine-ABC-transporter-substrate-binding-protein
MKRKIWLLPLLAVSAYLQAQTEVRLAVHKSFSLPKGLIARFERANDAKVSIIQAGGANEMLNKLILSRANPIADAVYGLDNANIGKAREMGILAAAQPESAPVAVGLPSALAVDYGYVSINYDKKWFEGKKLPLPQTLQDLTRPEYKNLLVVPSPATSSPGLGFLMANISGMGEEGAFKWWAQMRQNGVKVAKGWSEAYYTDFSHNGGAYPLVVGYAASPAAEVYFSKGKYSEPPTGNLFLKGGVFRQVEGAAVLKGAKQPKLAAKLVQWLQSREVQQAVPSEMWVYPAVKNTRLPDVFRFAQAPTHTTAPAQRDIDANQRGWVSRWIRTVLK
>NZ_FERW01000008.1|WP_042743324.1|71841_72522_+|pyrimidine-5'-nucleotidase
MQENPTVWLFDLDNTLHNADAGIFHLINRAMTRYMAHRLKLSESAASDLRQEYWHRYGATLAGLQIHHPEIDIADFLRESHPIDAILTRLHGMPETQNTLSRLKGRKAVFSNGPSFYVRAVVGALGLENRFDALFGTDDFGLLYKPNPQAYLNVCRLLDVPPECCIMVDDSADNLHQAKALGMKTVWFGAKSHALSFIDACARDMAQLARYAETLSEHRQTHYNTL
>NZ_FERW01000008.1|WP_002237405.1|72547_72820_+|hypothetical-protein
MRKTFLILMTTAALLSGCAWETYQDGNGKTAVRQKYPAGTPVYYQDGSYSKNMNYNQYRPERHAVLPNQTGNNADEEHRQHWQKPKFQNR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000008_1	1.1\|60678\|34\|NZ_FERW01000008\|CRISPRCasFinder	60678-60711	34	NZ_FERW01000007.1	2181-2214	1	0.971
NZ_FERW01000008_1	1.1\|60678\|34\|NZ_FERW01000008\|CRISPRCasFinder	60678-60711	34	NZ_FERW01000008.1	64765-64798	2	0.941

1. spacer 1.1|60678|34|NZ_FERW01000008|CRISPRCasFinder matches to position: 2181-2214, mismatch: 1, identity: 0.971

gtcttttataaactttgaatattgctgttatccc	CRISPR spacer
gtcttttataatctttgaatattgctgttatccc	Protospacer
*********** **********************

2. spacer 1.1|60678|34|NZ_FERW01000008|CRISPRCasFinder matches to position: 64765-64798, mismatch: 2, identity: 0.941

gtcttttataaactttgaatattgctgttatccc	CRISPR spacer
gtcttttataacctttgaatattgccgttatccc	Protospacer
*********** *************.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_FERW01000008_1	1.1\|60678\|34\|NZ_FERW01000008\|CRISPRCasFinder	60678-60711	34	NZ_LR699116	Aquicella lusitana strain SGT-39 plasmid 3	2708-2741	11	0.676

1. spacer 1.1|60678|34|NZ_FERW01000008|CRISPRCasFinder matches to NZ_LR699116 (Aquicella lusitana strain SGT-39 plasmid 3) position: , mismatch: 11, identity: 0.676

gtcttttataaactttgaatattgctgttatccc	CRISPR spacer
tccttttataaaatttgaatatttctaactttgg	Protospacer
 .********** ********** **. . *.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

15. NZ_FERW01000030

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

16. NZ_FERW01000028

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000028_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000028_1

27110-27287

Orphan

I-E

Consensus_repeat	Method
ATCCCGTCATTTCCGCGCAGGCGGGAATCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_FERW01000028_1

>merge|NZ_FERW01000028|1|27110-27287|CRISPRCasFinder
ATCCCGTCATTTCCGCGCAGGCGGGAATCCGAACGCGTCCGCACGGAAACCTGCACCACGTCATTCCCACGTATATCCCGTCATTCCCGCGCAGGCGGGAATCCAGTGCGTTGAGTTTCAGCTATTTAGAATAAATTTTGAAACTCTAATCGCGTCATTCCCACGAAAGTGGGAATCC

>NZ_FERW01000028|1|1|27110-27287|CRISPRCasFinder
ATCCCGTCATTTCCGCGCAGGCGGGAATCC	GAACGCGTCCGCACGGAAACCTGCACCACGTCATTCCCACGTAT
ATCCCGTCATTCCCGCGCAGGCGGGAATCC	AGTGCGTTGAGTTTCAGCTATTTAGAATAAATTTTGAAACTCTA
ATCGCGTCATTCCCACGAAAGTGGGAATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000028.1\|WP_002218843.1\|11556_12480_-\|agmatinase	unknown	unknown	gnl\|CDD\|235011
NZ_FERW01000028.1\|WP_002216588.1\|14637_14922_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379323
NZ_FERW01000028.1\|WP_002212563.1\|12578_14471_-\|biosynthetic-arginine-decarboxylase	unknown	unknown	gnl\|CDD\|224088
NZ_FERW01000028.1\|WP_002223471.1\|15072_16881_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_FERW01000028.1\|WP_002212560.1\|16938_17640_-\|DUF502-domain-containing-protein	unknown	unknown	gnl\|CDD\|225480
NZ_FERW01000028.1\|WP_002212556.1\|19091_19355_-\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NZ_FERW01000028.1\|WP_042743389.1\|22082_24815_-\|lactoferrin/transferrin-family-TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273799
NZ_FERW01000028.1\|WP_079758482.1\|17782_18931_-\|phospholipase-A	unknown	unknown	gnl\|CDD\|225385
NZ_FERW01000028.1\|WP_002216584.1\|19658_20801_+\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_FERW01000028.1\|WP_061375347.1\|24901_27010_-\|transferrin-binding-protein-like-solute-binding-protein	unknown	unknown	gnl\|CDD\|366565

Protein	Function_ID	Function_description	E-value
NZ_FERW01000028.1\|WP_002218843.1\|11556_12480_-\|agmatinase	gnl\|CDD\|235011	PRK02190, PRK02190, agmatinase; Provisional.	0
NZ_FERW01000028.1\|WP_002216588.1\|14637_14922_-\|PepSY-domain-containing-protein	gnl\|CDD\|379323	pfam13670, PepSY_2, Peptidase propeptide and YPEB domain. This region is likely to have a protease inhibitory function (personal obs:C Yeats). The name is derived from Peptidase & Bacillus subtilis YPEB.	1.5773e-15
NZ_FERW01000028.1\|WP_002212563.1\|12578_14471_-\|biosynthetic-arginine-decarboxylase	gnl\|CDD\|224088	COG1166, SpeA, Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism].	0
NZ_FERW01000028.1\|WP_002223471.1\|15072_16881_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_FERW01000028.1\|WP_002212560.1\|16938_17640_-\|DUF502-domain-containing-protein	gnl\|CDD\|225480	COG2928, COG2928, Uncharacterized conserved protein [Function unknown].	2.84331e-90
NZ_FERW01000028.1\|WP_002212556.1\|19091_19355_-\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.77816e-24
NZ_FERW01000028.1\|WP_042743389.1\|22082_24815_-\|lactoferrin/transferrin-family-TonB-dependent-receptor	gnl\|CDD\|273799	TIGR01776, Lactoferrin-binding_protein_A, TonB-dependent lactoferrin and transferrin receptors. This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	0
NZ_FERW01000028.1\|WP_079758482.1\|17782_18931_-\|phospholipase-A	gnl\|CDD\|225385	COG2829, PldA, Outer membrane phospholipase A [Cell envelope biogenesis, outer membrane].	3.25028e-156
NZ_FERW01000028.1\|WP_002216584.1\|19658_20801_+\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.39298e-129
NZ_FERW01000028.1\|WP_061375347.1\|24901_27010_-\|transferrin-binding-protein-like-solute-binding-protein	gnl\|CDD\|366565	pfam01298, TbpB_B_D, C-lobe and N-lobe beta barrels of Tf-binding protein B. Bacterial lipoproteins represent a large group of specialized membrane proteins that perform a variety of functions including maintenance and stabilization of the cell envelope, protein targeting and transit to the outer membrane, membrane biogenesis, and cell adherence. Pathogenic Gram-negative bacteria within the Neisseriaceae and Pasteurellaceae families rely on a specialized uptake system, characterized by an essential surface receptor complex that acquires iron from host transferrin (Tf) and transports the iron across the outer membrane. They have an iron uptake system composed of surface exposed lipoprotein, Tf-binding protein B (TbpB), and an integral outer-membrane protein, Tf-binding protein A (TbpA), that together function to extract iron from the host iron binding glycoprotein (Tf). TbpB is a bilobed (N and C lobe) lipid-anchored protein with each lobe consisting of an eight-stranded beta barrel flanked by a handle domain made up of four (N lobe) or eight (C lobe) beta strands. TbpB extends from the outer membrane surface by virtue of an N-terminal peptide region that is anchored to the outer membrane by fatty acyl chains on the N-terminal cysteine and is involved in the initial capture of iron-loaded Tf. This domain family is found in C and N lobe eight stranded beta barrel region of TbpB proteins. The eight-stranded barrel domains in N and C lobe draw comparisons to eight-stranded beta barrel outer-membrane protein W (OmpW). However, the barrel domains of TbpB have the hydrophobic residues line the inner surface of the beta barrels to create a stable hydrophobic core.	6.67708e-31

>NZ_FERW01000028.1|WP_061375347.1|24901_27010_-|transferrin-binding-protein-like-solute-binding-protein
MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVDTEAPRPAPKYQDVSSEKPQAQKDQGGYGFAMRFKRRNWYPRANPKEDEIKLSENDWEQTDNGNIKNPSKQKNIINALPGNNGEALLQDSSQENQGISKVTGHHNFRYVWSGFFYKQIPTKVETIDSKITARSGPDGYIFYKGKDPSRKLPVSGEVMYKGTWDFLTDVKANQKFTDLGNASTKPGDRYSAFSGELDYIVKQENDKKDGHVGLGLTTEITVDFEKKTLSGRLIKNNSVITNNDKHTTQYYSLNATLKGNRFSGKAEATDKPKKDGETKEHPFVSDSSSLSGGFFGPQGEELGFRFLSDDKKVAVVGSAKTKDKAESGGGNGASGGTGAAASNSAAGTSSENSKLTTVLDAVELTLNDKKIKKLDNFSNAAQLVVDGIMIPLLPEASESGHNQANQGTNGGTAFTRKFDHTPKSDKKDTQAQTGTGGAQAASGKADVNGGKAETKTYEVEVCCSNLNYLKYGMLTRKNSKSAMQAGENGSQADAKTEQVEQSMFLQGERTDEKEIPKEQQDIVYRGSWYGHIANDTSWSGNASDREGGNRADFTVNFGTKKINGTLTAENRQQATFTIEGDIKDNGFEGTAKTDDLGFDLDQKNTTRTPKAYITNAKVQGGFYGPKAEELGGWFAYLGDKQTEKATDASGNGNSASSATVVFGAKRQQPVR
>NZ_FERW01000028.1|WP_042743389.1|22082_24815_-|lactoferrin/transferrin-family-TonB-dependent-receptor
MQQQHLFRLNILCLSLMTALPVYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDDSKYAYFIVEEECESKNYETCKANPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDENRKYGPIRGNGKYAGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYHQSANRAYSSKTPPKTANPNGDKSKPYWVSIGGGNVVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRSGDKIKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIQNGKETAKGDPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVHVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF
>NZ_FERW01000028.1|WP_002216584.1|19658_20801_+|polyamine-ABC-transporter-substrate-binding-protein
MKKSVLAVLAALSLAACGGSEKNAVQPQADAASAANAEAAATDTLNIYNWSNYVDESTVEDFKKANNLKLTYDLYENNETLEAKMLTGKSGYDLVVPGIAFLPRQIEAGAYQKVNKDLIPNYKNIDPELLKMLETADPGNQYAVPYFSGVNTIAITAKGKELLGGKLPENGWDLLFKPEYTHKLKSCGIALWDTPSEMFPILLNYLGKDPKGSNPEDLKAAAEVLKSIRPDVKRFSPSIIDELARGDICLAAGNGGDLNLAKARSEEVKNNVGIEVLNPKGMGFWIESWLIPADAKNVANAHKYINYTLDPEIAAKNGIAVTFAPASKPAREKMPAELVNTRSIFPNEQDMKDGFVMPQMSTDAKKLSVSLWQKIKVGTN
>NZ_FERW01000028.1|WP_002212556.1|19091_19355_-|30S-ribosomal-protein-S20
MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDKAAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA
>NZ_FERW01000028.1|WP_079758482.1|17782_18931_-|phospholipase-A
MPTMGAEMNTRNMRYILLTGLLPTVSAFGETALQCAALTDNVTRLACYDRIFAAQLPSSAGQEGQESKAVLNLTETVRSSLDKGEAVIVVEKGGDALPADSAGETADIYTPLSLMYDLDKNDLRGLLGVREHNPMYLMPLWYNNSPNYAPSSPTRGTTVQEKFGQQKRAETKLQVSFKSKIAEDLFKTRADLWFGYTQRSDWQIYNQGRKSAPFRNTDYKPEIFLTQPVKADLPFGGRLRMLGAGFVHQSNGQSRPESRSWNRIYAMAGMEWGKLTVIPRVWVRAFDQSGDKNDNPDIADYMGYGDVKLQYRLNDRQNVYSVLRYNPKTGYGAIEAAYTFPIKGKLKGVVRGFHGYGESLIDYNHKQNGIGIGLMFNDLDGI
>NZ_FERW01000028.1|WP_002212560.1|16938_17640_-|DUF502-domain-containing-protein
MTEPAAEGGKAAKALKKYLITGILVWLPIAVTVWVVSYIVSASDQLVNLLPKQWRPQYVLGFNIPGLGVIVAIAVLFVTGLFAANVLGRQILAAWDSLLGRIPVVKSIYSSVKKVSESLLSDSSRSFKTPVLVPFPQSGIWTIAFVSGQVSNAVKAALPKDGDYLSVYVPTTPNPTGGYYIMVKKSDVRELDMSVDEALKYVISLGMVIPDDLPVKTLAGPMPSEKADLPEQQ
>NZ_FERW01000028.1|WP_002223471.1|15072_16881_-|aspartate--tRNA-ligase
MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFGADKTKVVNEAIGALRIKVGLEHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKVAETKEA
>NZ_FERW01000028.1|WP_002216588.1|14637_14922_-|PepSY-domain-containing-protein
MKKLLLAAVVSLSAATAFAGDSAERQIYGDPHFEQNRTKAVKMLEQRGYQVHDVDADDHWGKPVLEVEAYKDGREYDIVLSYPDLKIIKEQLDR
>NZ_FERW01000028.1|WP_002212563.1|12578_14471_-|biosynthetic-arginine-decarboxylase
MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPSQHNQTVSLQKLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQHRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEKLGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLSASQVLQLVDILKQKNRLDCLQLLHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNIRCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYAATVVWGISQACLEHGLPHPTIITESGRGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSWIHEGQFDLADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQERFADKLYVNFSLFQSLPDAWGIDQLFPVCPITGLNEPIARRAVLLDITCDSDGTIDHYIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVVVGEDGQFTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGYTYLEDE
>NZ_FERW01000028.1|WP_002218843.1|11556_12480_-|agmatinase
MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESQADWVITGVPYDMAVSGRSGARFGSEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYENGSEYDHGTMFYTAPKEGIIDPAHSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000007.1	2027-2070	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000008.1	59662-59705	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000008.1	64436-64479	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000009.1	29-72	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000009.1	654-697	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000011.1	940-983	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000017.1	1036-1079	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000022.1	858-901	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000032.1	19307-19350	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000037.1	13483-13526	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000037.1	14467-14510	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000040.1	8687-8730	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000040.1	8833-8876	1	0.977
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000043.1	6769-6812	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000043.1	7113-7156	0	1.0
NZ_FERW01000028_1	1.2\|27214\|44\|NZ_FERW01000028\|CRISPRCasFinder	27214-27257	44	NZ_FERW01000043.1	7608-7651	1	0.977

1. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 2027-2070, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

2. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 59662-59705, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

3. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 64436-64479, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

4. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 29-72, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaacttta	Protospacer
*****************************************.**

5. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 654-697, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaacttta	Protospacer
*****************************************.**

6. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 940-983, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agttcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
*** ****************************************

7. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 1036-1079, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

8. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 858-901, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

9. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 19307-19350, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaacttta	Protospacer
*****************************************.**

10. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 13483-13526, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

11. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 14467-14510, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

12. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 8687-8730, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttaagtttcagctatttagaataaattttgaaactcta	Protospacer
********.***********************************

13. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 8833-8876, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttaagtttcagctatttagaataaattttgaaactcta	Protospacer
********.***********************************

14. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 6769-6812, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

15. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 7113-7156, mismatch: 0, identity: 1.0

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agtgcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
********************************************

16. spacer 1.2|27214|44|NZ_FERW01000028|CRISPRCasFinder matches to position: 7608-7651, mismatch: 1, identity: 0.977

agtgcgttgagtttcagctatttagaataaattttgaaactcta	CRISPR spacer
agttcgttgagtttcagctatttagaataaattttgaaactcta	Protospacer
*** ****************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

17. NZ_FERW01000009

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

18. NZ_FERW01000010

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000010_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000010_1

73524-73630

Orphan

Consensus_repeat	Method
TTTATCGGAAATGACCGAAACTCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000010_1

>merge|NZ_FERW01000010|1|73524-73630|CRISPRCasFinder
TTTATCGGAAATGACCGAAACTCAACGAACCTGGATTCCCGCTTTCGCGGGAATGACGGGGGTGTGGCGGGAATGACGGGGGTTTATCAGAAATGACCGAAACTCAA

>NZ_FERW01000010|1|1|73524-73630|CRISPRCasFinder
TTTATCGGAAATGACCGAAACTCAA	CGAACCTGGATTCCCGCTTTCGCGGGAATGACGGGGGTGTGGCGGGAATGACGGGGG
TTTATCAGAAATGACCGAAACTCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_FERW01000010.1\|WP_002218624.1\|76951_77959_+\|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235388
NZ_FERW01000010.1\|WP_002218621.1\|71875_72727_+\|RNA-polymerase-sigma-54-factor	unknown	unknown	gnl\|CDD\|224425
NZ_FERW01000010.1\|WP_002223317.1\|80277_82968_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	unknown	unknown	gnl\|CDD\|236836
NZ_FERW01000010.1\|WP_002218622.1\|75080_76328_-\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NZ_FERW01000010.1\|WP_002221878.1\|60327_61713_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
NZ_FERW01000010.1\|WP_002218614.1\|57131_59108_+\|potassium-transporter	unknown	unknown	gnl\|CDD\|235131
NZ_FERW01000010.1\|WP_014575118.1\|60158_60257_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225308
NZ_FERW01000010.1\|WP_002235395.1\|65431_67468_+\|M3-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223416
NZ_FERW01000010.1\|WP_002218617.1\|61811_64202_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|237860
NZ_FERW01000010.1\|WP_002218625.1\|77974_78154_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000010.1\|WP_002218618.1\|64357_65344_+\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NZ_FERW01000010.1\|WP_002215584.1\|79035_79509_+\|DUF2247-family-protein	unknown	unknown	gnl\|CDD\|226754
NZ_FERW01000010.1\|WP_002215582.1\|78701_78983_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000010.1\|WP_002215587.1\|79762_80098_+\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000010.1\|WP_002218620.1\|70013_71528_-\|catalase	unknown	unknown	gnl\|CDD\|163712
NZ_FERW01000010.1\|WP_014575121.1\|69716_69938_-\|hypothetical-protein	unknown	unknown	unknown
NZ_FERW01000010.1\|WP_002215574.1\|76483_76720_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_FERW01000010.1\|WP_002216303.1\|68090_68657_-\|manganese-efflux-pump-MntP-family-protein	unknown	unknown	gnl\|CDD\|224882
NZ_FERW01000010.1\|WP_002215580.1\|78291_78615_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_FERW01000010.1\|WP_002218624.1\|76951_77959_+\|quinone-dependent-dihydroorotate-dehydrogenase	gnl\|CDD\|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NZ_FERW01000010.1\|WP_002218621.1\|71875_72727_+\|RNA-polymerase-sigma-54-factor	gnl\|CDD\|224425	COG1508, RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog [Transcription].	6.04701e-77
NZ_FERW01000010.1\|WP_002218622.1\|75080_76328_-\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_FERW01000010.1\|WP_002221878.1\|60327_61713_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_FERW01000010.1\|WP_002218614.1\|57131_59108_+\|potassium-transporter	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	5.3232e-105
NZ_FERW01000010.1\|WP_014575118.1\|60158_60257_+\|hypothetical-protein	gnl\|CDD\|225308	COG2510, COG2510, Predicted membrane protein [Function unknown].	1.06992e-05
NZ_FERW01000010.1\|WP_002235395.1\|65431_67468_+\|M3-family-metallopeptidase	gnl\|CDD\|223416	COG0339, Dcp, Zn-dependent oligopeptidases [Amino acid transport and metabolism].	0
NZ_FERW01000010.1\|WP_002218617.1\|61811_64202_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|237860	PRK14939, gyrB, DNA gyrase subunit B; Provisional.	0
NZ_FERW01000010.1\|WP_002218618.1\|64357_65344_+\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	6.52691e-18
NZ_FERW01000010.1\|WP_002215584.1\|79035_79509_+\|DUF2247-family-protein	gnl\|CDD\|226754	COG4304, COG4304, Uncharacterized protein conserved in bacteria [Function unknown].	7.88724e-84
NZ_FERW01000010.1\|WP_002215574.1\|76483_76720_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	4.37824e-37
NZ_FERW01000010.1\|WP_002218620.1\|70013_71528_-\|catalase	gnl\|CDD\|163712	cd08156, catalase_clade_3, Clade 3 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 3 catalases are the most abundant subfamily and are found in all three kingdoms of life; they have a relatively small subunit size of 43 to 75 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. Clade 3 catalases also bind NADPH as a second redox-active cofactor. They form tetramers, and in eukaryotic cells, catalases are located in peroxisomes.	0
NZ_FERW01000010.1\|WP_002216303.1\|68090_68657_-\|manganese-efflux-pump-MntP-family-protein	gnl\|CDD\|224882	COG1971, COG1971, Predicted membrane protein [Function unknown].	8.66041e-58
NZ_FERW01000010.1\|WP_002223317.1\|80277_82968_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	gnl\|CDD\|236836	PRK11072, PRK11072, bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase.	0

>NZ_FERW01000010.1|WP_002218621.1|71875_72727_+|RNA-polymerase-sigma-54-factor
MTLLGIKLKQTQQLNQRLQQSLRVLQMSGIELEREVENWLSDNPLLERKDTDEFSDAEFSHYTAPARQIGGDEGEDMLSNIAGEQDFKQYLHAQVCEHPLSDQESACVHILIDFLDEQGYLTDSIEDILDHTPLEWMLDEAMLKQALTALKKFDPAGVAAADLNESLILQIERSGECAAKPSALHIVRNALDSIDGNRSQTLARIKKRLPQTDSGTLEAALDLIASLNPFPAAGFASSTPTPYSDEALANLLAFRGMEVSRRTIAKYRESFEIPAAHKRKTAE
>NZ_FERW01000010.1|WP_002218620.1|70013_71528_-|catalase
MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKFHFRTQQGIKNLTNEEAAKIIADDRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAPSNLVPGVGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSFGQWQQQPDFAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGVAKALGLTVEDAQAARATDPALGQAGLL
>NZ_FERW01000010.1|WP_014575121.1|69716_69938_-|hypothetical-protein
MPSETSFDRFRRHFPIPPPPFQWAFFIKRKISRHSRPTAHFSAVIPAPSPPVQTGTKTFPRHSRESGNLERKI
>NZ_FERW01000010.1|WP_002216303.1|68090_68657_-|manganese-efflux-pump-MntP-family-protein
MSLYALLLIALGMSMDAFAVALAKGAAVRMPPRKIAATALVFGSVEALTPLAGWVGGFYAKPFISEWDHWAAFVLLGGLGLKMMREGLSGKAEDVRESKRESLWMTVLTAFGTSIDSMIVGVGLAFMEVNIAFAAAIIGMATTVMVAVGLTAGRALGVLFGRRAEFAGGLVLIAIGTWTLLSHLGLIQ
>NZ_FERW01000010.1|WP_002235395.1|65431_67468_+|M3-family-metallopeptidase
MTDNALLHLGEEPRFDQIKTEDIKPALQTAIAEAREQIAAIKAQTHTGWANTVEPLTGITERVGRIWGVVSHLNSVADTPELRAVYNELMPEITVFFTEIGQDIELYNRFKTIKNSPEFDTLSPAQKTKLNHDLRDFVLSGAELPPEQQAELAKLQTEGAQLSAKFSQNVLDATDAFGIYFDDAAPLAGIPEDALAMFAAAAQSESKTGYKIGLQIPHYLAVIQYADNRELREQIYRAYVTRASELSDDGKFDNTANIDRTLANALQTAKLLGFKNYAELSLATKMADTPEQVLNFLHDLARRAKPYAEKDLAEVKAFARESLNLADLQPWDLGYASEKLREAKYAFSETEVKKYFPVGKVLNGLFAQIKKLYGIGFTEKTVPVWHKDVRYFELQQNGETIGGVYMDLYAREGKRGGAWMNDYKGRRRFSDGTLQLPTAYLVCNFAPPVGGREARLSHDEILILFHETGHGLHHLLTQVDELGVSGINGVEWDAVELPSQFMENFVWEYNVLAQMSTHEETGEPLPKELFDKMLAAKNFQRGMFLVRQMEFALFDMMIYSEDDEGRLKNWQQVLDSVRKEVAVIQPPEYNRFALSFGHIFAGGYSAGYYSYAWAEVLSADAYAAFEESDDVAATGKRFWQEILAVGGSRSAAESFKAFRGREPSIDALLRHSGFDNAA
>NZ_FERW01000010.1|WP_002218618.1|64357_65344_+|mechanosensitive-ion-channel-family-protein
MKRYVCLRHQVGDFPVKWQKRFFATKIYTLYFSDRGAEMEIWNMLDTWLGAVPIRAEAVESVAAVAALLLARALLLNIHFKRHPDFGIESKRRFLVASRNITLLLVLFSLAFIWSAQIQTLALSMFAVAAAVVVATKELIMCLSGSILRSATQQYSVGDYIEINGLRGRVVDINLLNTLMMQVGPNPLVGQLAGTTVSFPNSLLLSHPVRRDNILGDYVIHTVEIPVPIHLDSDEAVCRLKAVLEPLCAPYIPAIQRHLENVQAEKLFITPAARPRVTRVPYDDKAYRIIVRFASPVSKRLEIQQAVMDEFLRVQYRLLNYPAGSETL
>NZ_FERW01000010.1|WP_002218617.1|61811_64202_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMVFEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGRGMPTGIHPKEGRSAAEVIMTVLHAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLNVVGDSDKKGTTVRFLASTETFGNVEYSFDILAKRIRELSFLNNGVDIELTDERDGKHESFALSGGVAGFVQYMNRKKTPLHEKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNIPQRDGGTHLTALRQVMTRTINSYIETNEVAKKAKVETAGDDMREGLTCVLSVKLPDPKFSSQTKDKLVSGEIGPVVNEVISQALTDFLEENPAEAKIITGKIVDAARAREAARKAREITRRKGVMDGLGLPGKLADCQEKDPALSELYLVEGDSAGGSAMQGRDRKFQAILPLKGKILNVEKARFEKMLASQEVAALITALGAGIGKEEFNAEKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLLGLALEKAKIVSDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENADKAVAELSGLLDEKEVALERIEGHEGHRFIKITRKLHGNVMVSYIEPKFLNSKAYQTLTQTAAALKGMVGEGAKLYKGENGYDADSFETALDILMSVAQKGMSIQRYKGLGEMNPEQLWETTMDPAVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA
>NZ_FERW01000010.1|WP_002221878.1|60327_61713_-|L-serine-ammonia-lyase
MVSIFDIFKIGIGPSSSHTVGPMKAAAAFAAGLDAQAVRIVIDIYGSLALTGYGHGTFDALMLGLEGSLPHDIPLVGIPERLERIRTQHILRLNGQEIRFIPDRDLNILGNQVLPKHPNGLRFTAYASDGTVLNEQVYYSVGGGFVVTEEDFDRQAETEKAVPYPYTSCAELLARCRLNRLDISEVVLANEAALAGCGEAEIRRRAAAVAEVMEGCIKRGLGADGELPGGLNVRRRAPQLAAKLKVLRETEIVNTQLWPMVYAMAVNEENAAGGRVVTAPTNGAAGIIPAVLHYFRKFNPHATQERVENFLLTAGAIGILYKTNASISGADVGCQGEVGVACSMAAGAYAEVIGGTPKQVENAAEMAMEHHLGLTCDPVGGLVQIPCIERNGIAAEKALKLGTLALLEDGTDKKVSLDEVIRTMLQTGRDMKATYKETSLAGLAATLRKKAVPVSVRVVEC
>NZ_FERW01000010.1|WP_014575118.1|60158_60257_+|hypothetical-protein
MAVVFLDERPNTQEWIGLGLVTAGVLTLALKR
>NZ_FERW01000010.1|WP_002218614.1|57131_59108_+|potassium-transporter
MNEFSLAPIVVVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPGMLSLIPKSHATDYLGEIGIVFLMFSIGLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVMGILMLTGVPFNWAFAVSGALAMSSTAIVSRILSEKTELGQPHGQMAMGVLLMQDIAVVPLMILIPALAGGGDGNIWAALGLAFAKMLLTLGLLFFVGSKIMSRWFRMVAKRKSSELFMINVLLVTLGVAYLTELEGLSMALGAFVAGMLLSETEYRFQVEDDIRPFRDILLGFFFITVGMKLDIQALIGGWRQVLMLLAMLLVLKALVVFAIAFKMKHSVGDSLKTALYLAQGGEFGFVMLAIAGQLDMVSPEWEQAATAAVLLSMIIAPFLLGGSDALVGRLVKSSWDMKSLDLHSMLVETMSKSDHVLIVGFGRGGQTVGRVLAQEDIPYFALDLDIARVQVARSAGEPVSFGDAKRREVLEAAGLGRAKMVVLTLNNMHETQHVLDNVLSMYPNMPVYVRATNDDYVKTFTDIGAEEAVSDTKETGLVLAGYAMLGNGASYRHVYQTMANIRHSRYAALEGLFVGSDDEAGFGENGETVRHAFPLAAEAYAVGKTVGTLPMAAYGIKLLFVRRRTGRIENPDASFTLEGGDVLVVAGKKEEIISFENWSLQGI
>NZ_FERW01000010.1|WP_002218622.1|75080_76328_-|beta-ketoacyl-ACP-synthase-II
MSQRRVVITGLGQVSPVGNTVAEAWDTLLTGKSGIGAITRFDASDINSRVAGEVRGFDIGQYISAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRIGVNIGSGIGGLPGIEVTGKAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYGMVSACTTGAHAIGDSLRMIKYGDADIMVAGGAEGAISTLGVGGFAAMKALSTRNDDPATASRPWDKGRDGFVIGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGINPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAGGVEAVYSILAIHDGKIPPTINIFEQDVEAGCDLDYCANEARDAEIDVAISNSFGFGGTNGTLVFKRFKG
>NZ_FERW01000010.1|WP_002215574.1|76483_76720_-|acyl-carrier-protein
MSNIEQQVKKIVAEQLGVNEADVKNESSFQDDLGADSLDTVELVMALEEAFGCEIPDEDAEKITTVQLAIDYINAHNG
>NZ_FERW01000010.1|WP_002218624.1|76951_77959_+|quinone-dependent-dihydroorotate-dehydrogenase
MYPLARRILFALDAEKAHHFTLDALYTVYKLGLIPVTGNRTKPVKLMGMDLPNPVGLAAGLDKNGEYIDALGALGFGFIEIGTVTPKPQPGNPQPRLFRVPEHQGIINRMGFNNHGIDTMIRNIEKSKFSGVLGINIGKNAVTPIENAADDYLICLEKAYAHASYITVNISSPNTKNLRALQGGDELSALLEALKNKQAQLASVYGKYVPLAVKIAPDLDEAQIEDIAHVVKSVEMDGIIATNTTIDKSSLGSHPLAGEQGGLSGRPVHEKSNRVLKLLADHIDGKLPIIGVGGIMEGRDAADKIRLGATAVQVYSGLIYKGPALVKECLKALAR
>NZ_FERW01000010.1|WP_002218625.1|77974_78154_+|hypothetical-protein
MPSERTFCRSDGIFISFFRLPPLENPLRAALFETKQTPAANRTILIRSQSKSGGKLLNI
>NZ_FERW01000010.1|WP_002215580.1|78291_78615_+|hypothetical-protein
MFKDELNEFIRLISDPESELDEWYLSDFKDEHIWEMQSYEAFSCLREAVPYLFAYPRYGYELLEIISALKETSDTTELFYEPGIVPLLIDLYKEDSYLVNMVKRIFK
>NZ_FERW01000010.1|WP_002215582.1|78701_78983_+|hypothetical-protein
MENGQRNNRFPLEKRIFYLEHSGRYLMICALSDYSQNKHTVVMANFIYPDEKTDWRNLDDLFNELVLEELQASFMDWHPTVEEAISRHLEDFS
>NZ_FERW01000010.1|WP_002215584.1|79035_79509_+|DUF2247-family-protein
MNLDLTAQKVRLSWKDILWGYGNKYLGWADVAAYARKMTLSDHDERVFKLSLINKSNILELKPVLEDLASEMRDYSPKNWLYVLLSDVFHRKEEFEDPLGEVEKIYADFDYPEEIESFVRYMPPKDGYIPSAHTYEENIARLYSHWEHYLNNGGGQG
>NZ_FERW01000010.1|WP_002215587.1|79762_80098_+|hypothetical-protein
MTVDKEQVEKMIYSENKQSVIDGMLGMTFSSEEDEIPWISEKLTELSKHKDLDIARLSLTCFGHLARMHENIGDCDKVIALLLSKQGDPDFQGFAEDALDEISLFIFKKRP
>NZ_FERW01000010.1|WP_002223317.1|80277_82968_+|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase
MSDNRLDTARRHSLFLARQLDNGKLKPEIFLPMLDKVLTEADFQAFADWDKIRAEENEEELARQLRGLRRYVVSQIIVRDINRISDLNEVTRTITLFADFAVNTALDFSYAYYQDMYGTPIGRYTKSPQHLSVVAMGKAGGYELNVSSDIDLIFIYPESGDTDGRRERGNQEFFTKVGQKLIALLNDITADGQVFRVDMRLRPDGDSGALVLSETALEQYLITQGREWERYAWCKGRVVTPYPNDIKSLVRPFVFRKYLDYGAYEAMRKLHRQIHSEVGKKGMADNIKLGAGGIREVEFIAQIFQMIRGGQMRALQLKGTRETLEKLAESGIMPSENVETLLAAYRFLRDVEHRLQYWDDRQTQTLPASPEQRQLLAESMGFDDYADFLNALNQHRNQVNRLFNEILSEPEEQTQSNSEWQWVWQDKPDEEERQGRLKEHGFDAETIATRLDQIRHSHKYRHLSAHAQPRFDAVVPLFVQAAAAQSNPTDTLMRLLDFLENISRRSAYLAFLNEHPQTLAQLAQIMGQSSWVAAYLNKYPILLDELISAQLLDTAFDWQALAAALSDDLKACGGDTEAQMDTLRHFQHAQVFRLAVQDLAGLWTVESLSDQLSALADTILAAALLCAWADMPKKHRDTPQFAVVGYGKLGGKELGYASDLDLVYLYDDPHPEAGDVYSRLARRLTNWLSTATGAGSLYETDLRLRPNGDAGFLAHSIAAFEKYQRENAWTWEHQSLTRARFICGTPEIQTAFDRIRTEILTAERDQTALADEIIEMREKMFPTHPPADSNVKYARGGVVDVEFIVQYLILAHARKYPQLLDNYGNIALLNIATDCGLIDKTLAEQSRTAYRFYRRQQHNTKLRDAEKTEVSGELLAHYGNVRKLWREVFGEEAATA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

19. NZ_FERW01000024

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6677

Acinetobacter_phage(16.67%)

integrase,transposase

attL 2596:2609|attR 9657:9670

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061727196.1\|0_415_-	N-acetylmuramoyl-L-alanine amidase	U5PZX6	Acinetobacter_phage	1.4e-30	52.9
WP_002219320.1\|557_1079_-	hypothetical protein	NA	NA	NA	NA
WP_002219321.1\|1080_2253_-	AAA family ATPase	A0A2D1GNS0	Pseudomonas_phage	1.5e-50	44.9
WP_002219322.1\|2298_2556_+	hypothetical protein	NA	NA	NA	NA
2596:2609	attL	NA	NA	NA	NA
WP_002223803.1\|2622_4611_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0M3LPN5	Mannheimia_phage	4.0e-115	41.9
WP_021437407.1\|4732_4936_-	winged helix-turn-helix DNA-binding family protein	F6MII4	Haemophilus_phage	1.2e-11	54.4
WP_002219323.1\|5157_5877_+	helix-turn-helix transcriptional regulator	A5X9F5	Aeromonas_virus	6.2e-26	37.2
WP_002223805.1\|6125_6677_+	ATP-binding cassette domain-containing protein	A0A2H4UU96	Bodo_saltans_virus	3.1e-09	28.0
9657:9670	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

20. NZ_FERW01000043

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

21. NZ_FERW01000037

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

22. NZ_FERW01000032

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

23. NZ_FERW01000029

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

24. NZ_FERW01000066

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CRISPR-Cas detection and classification

Crispr_ID: NZ_FERW01000066_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_FERW01000066_1

598-700

Orphan

I-E

Consensus_repeat	Method
CCGTCATTCCCGCGCAGGCGGGAATCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_FERW01000066_1

>merge|NZ_FERW01000066|1|598-700|CRISPRCasFinder
CCGTCATTCCCGCGCAGGCGGGAATCCGGCTTGTACGGTTTCGGTTTTTTTTTTGAGGTTTCGGGCAACTTCTAAACCGTCATTCCCGCGCAGGCGGGAATCC

>NZ_FERW01000066|1|1|598-700|CRISPRCasFinder
CCGTCATTCCCGCGCAGGCGGGAATCC	GGCTTGTACGGTTTCGGTTTTTTTTTTGAGGTTTCGGGCAACTTCTAAA
CCGTCATTCCCGCGCAGGCGGGAATCC

>NZ_FERW01000066.1|WP_002216166.1|311_596_+|GIY-YIG-nuclease-family-protein
MQPAVYILASQRNGTLYIGVTSDLVQRIYQHREHLIEGFTSRYNVTMLVWYELHPTMESAITREKQLKKWNRAWKLQLIEENNVSWQDLWFDII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_FERW01000066_1	1.1\|625\|49\|NZ_FERW01000066\|CRISPRCasFinder	625-673	49	NZ_FERW01000010.1	44823-44871	1	0.98

1. spacer 1.1|625|49|NZ_FERW01000066|CRISPRCasFinder matches to position: 44823-44871, mismatch: 1, identity: 0.98

ggcttgtacggtttcggttttttttttgaggtttcgggcaacttctaaa	CRISPR spacer
ggcttgttcggtttcggttttttttttgaggtttcgggcaacttctaaa	Protospacer
******* *****************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage