CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CABHGG010000001	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	2 crisprs	csn2,cas2,cas1,cas9,cas3,DinG,DEDDh,csa3	7	5	0
NZ_CABHGG010000022	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000020	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000017	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000002	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000024	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000003	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	cas3,csa3,WYL	0	0	0
NZ_CABHGG010000008	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000012	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CABHGG010000013	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000011	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000019	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000023	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000010	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	1 crisprs	NA	2	0	0
NZ_CABHGG010000004	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CABHGG010000018	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000006	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000021	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000009	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	1	0
NZ_CABHGG010000016	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0
NZ_CABHGG010000014	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	2
NZ_CABHGG010000007	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	DinG	0	0	0
NZ_CABHGG010000005	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	cas14j,cas3	0	1	0
NZ_CABHGG010000015	Enterococcus faecalis strain 4928STDY7387806, whole genome shotgun sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CABHGG010000001_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CABHGG010000001_1

523487-524116

TypeII

Consensus_repeat	Method
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	CRT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	PILER-CR
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	CRISPRCasFinder

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CABHGG010000001_1

>merge|NZ_CABHGG010000001|1|523487-524116|CRT,PILER-CR,CRISPRCasFinder
GATGGCTTTTTTGAAAATTATTGGGAGTATAAAAGCGAGTTCGTACATCCAACCTACTTCCTTATTGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACTATTGGGCAACGATTCTTTCTTTAATCCCTGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACAAAATTCTGCGATGAAGTGAATCAACATGTGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACCAAATCGTACATTTATAACCATCGCGAAAAGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACAAGCAGAAGAATTTATCAATGCTTCAAAAAGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACAAGAATGGGACCAGATCGGCTGGGGAACGAGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACTACTAATCGTTCATTCAATGCTTGCTCGTTGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACGATTGAGGGAATTTTGATTGATGCTGGTTAGTTTTACTGATAAGAAATTATTGAGAGTACAAAAACACCTTGTTGAAGAACGGTGAAATAGCTTTAGTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC

>NZ_CABHGG010000001|1|1|523487-524116|CRT
GATGGCTTTTTTGAAAATTATTGGGAGTATAAAAGC	GAGTTCGTACATCCAACCTACTTCCTTATT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TATTGGGCAACGATTCTTTCTTTAATCCCT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAAATTCTGCGATGAAGTGAATCAACATGT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	CAAATCGTACATTTATAACCATCGCGAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGCAGAAGAATTTATCAATGCTTCAAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGAATGGGACCAGATCGGCTGGGGAACGA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TACTAATCGTTCATTCAATGCTTGCTCGTT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	GATTGAGGGAATTTTGATTGATGCTGGTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	ACCTTGTTGAAGAACGGTGAAATAGCTTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC

>NZ_CABHGG010000001|1|1|523553-524116|PILER-CR
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TATTGGGCAACGATTCTTTCTTTAATCCCT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAAATTCTGCGATGAAGTGAATCAACATGT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	CAAATCGTACATTTATAACCATCGCGAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGCAGAAGAATTTATCAATGCTTCAAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGAATGGGACCAGATCGGCTGGGGAACGA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TACTAATCGTTCATTCAATGCTTGCTCGTT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	GATTGAGGGAATTTTGATTGATGCTGGTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	ACCTTGTTGAAGAACGGTGAAATAGCTTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC

>NZ_CABHGG010000001|1|1|523553-524116|CRISPRCasFinder
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TATTGGGCAACGATTCTTTCTTTAATCCCT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAAATTCTGCGATGAAGTGAATCAACATGT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	CAAATCGTACATTTATAACCATCGCGAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGCAGAAGAATTTATCAATGCTTCAAAAA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	AAGAATGGGACCAGATCGGCTGGGGAACGA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	TACTAATCGTTCATTCAATGCTTGCTCGTT
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	GATTGAGGGAATTTTGATTGATGCTGGTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC	ACCTTGTTGAAGAACGGTGAAATAGCTTTA
GTTTTACTGATAAGAAATTATTGAGAGTACAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CABHGG010000001.1\|WP_002357299.1\|521381_522302_-\|phosphate-ABC-transporter-permease-subunit-PstC	unknown	unknown	gnl\|CDD\|223646
NZ_CABHGG010000001.1\|WP_002357307.1\|515645_516002_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377198
NZ_CABHGG010000001.1\|WP_002361935.1\|531473_532160_-\|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl\|CDD\|225438
NZ_CABHGG010000001.1\|WP_002357293.1\|536236_536788_-\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CABHGG010000001.1\|WP_010715262.1\|526696_530149_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
NZ_CABHGG010000001.1\|WP_016614655.1\|525571_526492_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CABHGG010000001.1\|WP_010715263.1\|536926_537613_-\|ComF-family-protein	unknown	unknown	gnl\|CDD\|223970
NZ_CABHGG010000001.1\|WP_010715260.1\|524193_525252_-\|hypothetical-protein	csn2	cd12217_csn2_CAS-II-A	gnl\|CDD\|213410
NZ_CABHGG010000001.1\|WP_002408903.1\|525251_525551_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CABHGG010000001.1\|WP_002357300.1\|520497_521382_-\|phosphate-ABC-transporter-permease-PstA	unknown	unknown	gnl\|CDD\|223654
NZ_CABHGG010000001.1\|WP_002357298.1\|522424_523279_-\|phosphate-ABC-transporter-substrate-binding-protein-PstS	unknown	unknown	gnl\|CDD\|273991
NZ_CABHGG010000001.1\|WP_002420121.1\|533443_535981_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CABHGG010000001.1\|WP_002357306.1\|516001_516325_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
NZ_CABHGG010000001.1\|WP_002360155.1\|516399_518001_-\|daptomycin-sensing-surface-protein-LiaX	unknown	unknown	gnl\|CDD\|226123
NZ_CABHGG010000001.1\|WP_002357304.1\|518210_518888_-\|phosphate-signaling-complex-protein-PhoU	unknown	unknown	gnl\|CDD\|273990
NZ_CABHGG010000001.1\|WP_111997025.1\|532265_533367_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CABHGG010000001.1\|WP_010715258.1\|514648_515611_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|234792
NZ_CABHGG010000001.1\|WP_002420128.1\|519671_520481_-\|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|237646
NZ_CABHGG010000001.1\|WP_002364071.1\|530596_531481_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|225088
NZ_CABHGG010000001.1\|WP_002357303.1\|518902_519661_-\|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|172743

Protein	Function_ID	Function_description	E-value
NZ_CABHGG010000001.1\|WP_002357299.1\|521381_522302_-\|phosphate-ABC-transporter-permease-subunit-PstC	gnl\|CDD\|223646	COG0573, PstC, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	1.29322e-99
NZ_CABHGG010000001.1\|WP_002357307.1\|515645_516002_-\|phage-holin-family-protein	gnl\|CDD\|377198	pfam04020, Phage_holin_4_2, Mycobacterial 4 TMS phage holin, superfamily IV. These proteins are predicted transmembrane proteins with probably four transmembrane spans. The 1.E.40 is represented by the mycobacterial 4 phage holin, but it also contains many cyanobacterial. proteobacterial and firmicute proteins. Holins are encoded within the genomes of Gram-positive and Gram-negative bacteria as well as in those of the bacteriophage of these organisms. The primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded the enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some may catalyze export of nucleases.	7.53845e-22
NZ_CABHGG010000001.1\|WP_002361935.1\|531473_532160_-\|cell-division-ATP-binding-protein-FtsE	gnl\|CDD\|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	1.10484e-139
NZ_CABHGG010000001.1\|WP_002357293.1\|536236_536788_-\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	9.1271e-38
NZ_CABHGG010000001.1\|WP_010715262.1\|526696_530149_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	7.6132e-115
NZ_CABHGG010000001.1\|WP_016614655.1\|525571_526492_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.84741e-97
NZ_CABHGG010000001.1\|WP_010715263.1\|536926_537613_-\|ComF-family-protein	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	3.1262e-36
NZ_CABHGG010000001.1\|WP_010715260.1\|524193_525252_-\|hypothetical-protein	gnl\|CDD\|213410	cd12217, Stu0660_Csn2, Stu0660-like CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. This family of Csn2 proteins includes Stu0660, the proteins are larger than other (canonical) Csn2 proteins as they have an additional alpha-helical C-terminal domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.29074e-115
NZ_CABHGG010000001.1\|WP_002408903.1\|525251_525551_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.41752e-22
NZ_CABHGG010000001.1\|WP_002357300.1\|520497_521382_-\|phosphate-ABC-transporter-permease-PstA	gnl\|CDD\|223654	COG0581, PstA, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	1.01734e-103
NZ_CABHGG010000001.1\|WP_002357298.1\|522424_523279_-\|phosphate-ABC-transporter-substrate-binding-protein-PstS	gnl\|CDD\|273991	TIGR02136, ptsS_2, phosphate binding protein. Members of this family are phosphate-binding proteins. Most are found in phosphate ABC-transporter operons, but some are found in phosphate regulatory operons. This model separates members of the current family from the phosphate ABC transporter phosphate binding protein described by TIGRFAMs model TIGR00975. [Transport and binding proteins, Anions].	3.17732e-122
NZ_CABHGG010000001.1\|WP_002420121.1\|533443_535981_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CABHGG010000001.1\|WP_002357306.1\|516001_516325_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	1.24173e-20
NZ_CABHGG010000001.1\|WP_002360155.1\|516399_518001_-\|daptomycin-sensing-surface-protein-LiaX	gnl\|CDD\|226123	COG3595, COG3595, Uncharacterized conserved protein [Function unknown].	6.18326e-14
NZ_CABHGG010000001.1\|WP_002357304.1\|518210_518888_-\|phosphate-signaling-complex-protein-PhoU	gnl\|CDD\|273990	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU. This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions].	6.09767e-88
NZ_CABHGG010000001.1\|WP_111997025.1\|532265_533367_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CABHGG010000001.1\|WP_010715258.1\|514648_515611_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	2.39335e-43
NZ_CABHGG010000001.1\|WP_002420128.1\|519671_520481_-\|phosphate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|237646	PRK14237, PRK14237, phosphate transporter ATP-binding protein; Provisional.	0
NZ_CABHGG010000001.1\|WP_002364071.1\|530596_531481_-\|ABC-transporter-permease	gnl\|CDD\|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	4.28311e-97
NZ_CABHGG010000001.1\|WP_002357303.1\|518902_519661_-\|phosphate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|172743	PRK14255, PRK14255, phosphate ABC transporter ATP-binding protein; Provisional.	0

>NZ_CABHGG010000001.1|WP_002357298.1|522424_523279_-|phosphate-ABC-transporter-substrate-binding-protein-PstS
MKKRLLLFIGLASILTLTGCAKWIDRGESITAVGSSALQPLVETASEEYQSQNPGRFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKKGIKAEDLIDHKVAVVGITPIVNKNVGVKDISMENLKKIFLGEVTNWKELGGKDQKIVILNRAAGSGTRATFEKWVLGDKTAIRAQEQDSSGMVRSIVSDTPGAISYTAFSYVTDEVATLSIDGVQPTDENVMNNKWIIWSYEHMYTRKNPSDLTKEFLDFMLSDDIQERVIGQLGYIPVSKMEIERDWQGNVIK
>NZ_CABHGG010000001.1|WP_002357299.1|521381_522302_-|phosphate-ABC-transporter-permease-subunit-PstC
MEDVQKKLLTKSKRAKMEQRGKFISFLCIALIVAVVVSIFYFVASKGLATFFKDKINVFDFLFGTNWNPSDIGADGKPMVGALPMIAGSFIVTFLSAIVATPFAIGAAVFMTEISPKKGAKFLQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFGILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGILTAVVFGMARAFGEALAIQMVIGNAAVMPTSLTTPASTLTSILTMGIGNTIMGTVENNVLWSLALILLLMSLLFNIVIRIIGKRGALK
>NZ_CABHGG010000001.1|WP_002357300.1|520497_521382_-|phosphate-ABC-transporter-permease-PstA
MNAKKADKIATGILYAVSGVIVLILAALLIYILARGIPHISWEFLTQPSRAYQVGGGIGIQLFNSLYLLLITMIISIPISLGAGIYLSEYAKKNWLTDLIRTSIEILSSLPSVVVGLFGFLIFVVQIGYGFSILSGALALTFFNLPLLTRNVEESLKAIHYTQREAGLALGLSRWETVKKVILPEALPGILTGVILSSGRIFGEAAALIYTAGQSAPALDFSNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGAAVSAGASAVLILVVLLFNFGARFIGNRLYKRMTSA
>NZ_CABHGG010000001.1|WP_002420128.1|519671_520481_-|phosphate-ABC-transporter-ATP-binding-protein
MKEYNLNDTHLLQLDSQKDPIALHTEDLHVFYGDNEAIKGVDLQFEKNKITALIGPSGCGKSTYLRSLNRMNDGIANTRVTGKIMYKDVDVNTKEVDVYEMRKRIGMVFQRPNPFSKSIYENITFALKQHGEKDKKKLDEIVETSLKQAALWDQVKDNLNKSALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKDDYTIIIVTHNMQQAARISDYTAFFYMGKVIEYDHTRKIFTRPKIQATEDYVSGHFG
>NZ_CABHGG010000001.1|WP_002357303.1|518902_519661_-|phosphate-ABC-transporter-ATP-binding-protein
MGKEIISSKDLHLYYGKKEALKGIDLTFNQGELTAMIGPSGCGKSTYLRCLNRMNDLIPDVTITGSVVYKGKDIYGPKTDNVELRKEIGMVFQQPNPFPFSVYENVIYGLRLKGVKDKQVLDEAVETSLKAAAVWEDVKDKLHKSALSLSGGQQQRVCIARVLAVEPDIILLDEPTSALDPVSSGKIENMLLTLKEKYTMIMVTHNMSQASRISDKTAFFLQGDLIEFNDTKKVFLNPKEKQTEDYISGKFG
>NZ_CABHGG010000001.1|WP_002357304.1|518210_518888_-|phosphate-signaling-complex-protein-PhoU
MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVKAYINHDKKLAQEVIDRDIEINDMEVKLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSIAKSTIRLKGETRIPEIEKEISDMSDYVKKMVDNVLIAYVKTDQKDARMIAQMDDRTNEYFDSIYKHAVEAMKANPETVISGTDYLHVAQYLERIGDYVTNICEWIVYLATGKITELNSNRDEQF
>NZ_CABHGG010000001.1|WP_002360155.1|516399_518001_-|daptomycin-sensing-surface-protein-LiaX
MKERERVLELVKKGILTSEEALILLENMATEKDEKQIEKAAEKVDTQNIGTTNKEDQVADLMDALEKGESEGPTVDSFEENTQDSAEKDRENLERILDELATKANRASAELDEVNAEIAGIKEEIKEVAEEIGTLDTKEELDALTEDEQVQRKDLHVLLAQLEEKLATQSTEKTALEEELKNIRKEQWKGQWNDTKEKVSSQFSEEWKDQATDTFNQVGGKVAEVGGQVGEFLKKTFNSFSDTMNDNVEWKDIKMKVPGVATTKFEHEFNYPNPQASLIDVKVANGTVVFKTWDQEDVKVEAKIKLYGKMAGDSPMEAFLERSDIDVDDETISFQVPNKRVKADLTFYLPKRTYDHVSVKLLNGNVLVEELTAKDVYTKSTNGTITFKKIDATMLEIEGVNGEIKVLEGTILDNIIETVNGDVSISAAPESLSVSLINGDIRITAKEKTLRRVEASSANGNIKLALPNDLGVEGQVKTNLGSINSRLTDIEVVREKKDRGNQQLHFRRVLEESMAQINASTTTGSIFLKDTDK
>NZ_CABHGG010000001.1|WP_002357306.1|516001_516325_-|PspC-domain-containing-protein
MKRKLTKSPNNVVLTGSLAGIADWLGIDPTIIRVVYVLLSFFSAGFPGILLYIALAVLIPSGRTGSDRGYGHQNPYNRNVRNENPYAANKKQRKEAEKIDDDEWSDF
>NZ_CABHGG010000001.1|WP_002357307.1|515645_516002_-|phage-holin-family-protein
MTYFQRLVVNTLTFISLSVVFPGMIHVRGIMPAIIAAFVLSILNMLVKPVLTILSLPFTLLTFGLFSFVVNAAILQMTSFFVGEMNFGFSSFWAAVLMAVIMSIVNTIVTDHNLSKYE
>NZ_CABHGG010000001.1|WP_010715258.1|514648_515611_+|GIY-YIG-nuclease-family-protein
MKEYLKEKAHQLALTPGVYLMKDATDTIIYVGKAKKLKNRVSSYFINSHQHSRKTMRLVKQIIDFDVLHTDTELDALLLECQLIQQYRPRYNRQMNAYEQYSYVSVAVNERQLEIKLLNMPTKENCFGPYSIRRKLNRLKIILDSIYDLVPTNYWHQTFQKESAIPTELFQQELFDFFHNQGREPIKRIAQQMQEAAEKQAFEKAAKLKEDWLFLTRFANQNQRISQANQRDWQLMWLPCQKKIKYYLIYQGLVVATRVVTKQTFQKYSPLELAKKIMPKKTPKTIEHYSKQQVDFLNILYGYISRHPECHLENLTIEKA
>NZ_CABHGG010000001.1|WP_010715260.1|524193_525252_-|hypothetical-protein
MKQIRLEYQYQQFIEFSLEDYVFFYGGENQWRRKILRTLKRFAKQKALSDLEESVYGDNGIEIFLEEKKLKAKSIDFYFLEDNTSIFQQINFIKGTLLHQELLYLQDDFDITNQMSNLNDQLLKLENLMNDKLNNYLTNIEPHFLEMNFQDILKYSLSLNYLENGQSLPLEMMDTGELLAEFIYLLQRSISRREQPVWLVITNPESFLETESIHYLFQQLKKLAQETKQLKFFIFSNRSLPLPYTEEDVEKTILLYDKYQQLPVFDVFRQSIERHYPDQLSWTNQQLIDAFYRVCHFVGDQYTKNYLLPKDMILLKLLKELLDDNSECVETSMEKLTVLEEQYFRERLLRKE
>NZ_CABHGG010000001.1|WP_002408903.1|525251_525551_-|CRISPR-associated-endonuclease-Cas2
MCLFDLPFETKQEQKEYRIFRKHLLENGFIMLQYSIYYRSLPNRSALKKYETILKRKVPRSGNVRLLYVSEIQFQDMLLLAGSRSHQEEVVGVRRLVVI
>NZ_CABHGG010000001.1|WP_016614655.1|525571_526492_-|type-II-CRISPR-associated-endonuclease-Cas1
MLLGFRTVFVKNGEKLKVKLDNLEVIKEGNTYVIPLTDIESVILEGDQTVITTRLLAKFAQHHIDTVICDNTFMPVGVFLGIGQYHRSAKRAIWQSNWKEEQKQVAWCEIVTQKIQNQIAVTKYLGTDSERVEVLEKLSEGILPGDTTNREGHVAKVYFHSLYGVGFTREEECLPNACMNYGYAVIRAQMARCVVALGLLPMLGIFHKNEYNSFNLVDDLMEPFRPLMDWYIHQTILKKNEKYLTYHSRLTLVEFLHQKIKVKNKKIYMNQAMSEYVAAFVKAMETGDFENVQKIHLVNMLECEGK
>NZ_CABHGG010000001.1|WP_010715262.1|526696_530149_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MYSIGLDLGISSVGWSVIDERTGNVIDLGVRLFSAKNSEKNLERRTNRGGRRLIRRKTNRLKDAKKILAAVGFYEDKSLKNSCPYQLRVKGLTEPLSRGEIYKVTLHILKKRGISYLDEVDTEAAKESQDYKEQVRKNAQLLTKYTPGQIQLQRLKENNRVKTGINAQGNYQLNVFKVSAYANELATILKTQQAFYPNELTDDWIALFVQPGIAEEAGLIYRKRPYYHGPGNEANNSPYGRWSDFQKKGEPATNIFDKLIGKDFQGELRASGLSLSAQQYNLLNDLTNLKIDGEVPLSSEQKEYILTELMTKEFTRFGVNDVVKLLGVKKERLSGWRLDKKGKPEIHTLKGYRNWRKIFAEAGIDLATLPTETIDCLAKVLTLNTEREGIENTLAFELPELSESVKLLVLDRYKELSQSISTQSWHRFSLKTLHLLIPELMNATSEQNTLLEQFQLKSDVRKRYSEYKKLPTKDVLAEIYNPTVNKTVSQAFKVIDALLVKYGKEQIRYITIEMPRDDNEEDEKKRIKELHAKNSQRKNDSQSYFMQKSGWSQEKFQTTIQKNRRFLAKLLYYYEQDGICAYTGLPISPELLVSDSTEIDHIIPISISLDDSINNKVLVLSKANQVKGQQTPYDAWMDGSFKKINGKFSNWDDYQKWVESRHFSHKKENNLLETRNIFDSEQVEKFLARNLNDTRYASRLVLNTLQSFFTNQETKVRVVNGSFTHTLRKNWGADLDKTRETHHHHAVDATLCAVTPFVKVSRYHYAVKEETGEKVMREIDFETGEIVNEMSYREFKKSKKYERKTYQVKWPNFREQLKPVNLHPRIKFSHQVDRKANRKLSDATIYSVREKTEVKTLKSGKQKITTDEYTIGKIKDIYTLDGWEAFKKKQDKLLMKDLDEKTYERLLSIAETTPDFQEVEEKNGKVKRVKRSPFAVYCEENDIPAIQKYAKKNNGPLIRSLKYYDGKLNKHINITKDSQGRPVEKTKNGRKVTLQSLKPYRYDIYQDLETKAYYTVQLYYSDLRFVEGKYGITEKEYMKKVAEQTKGQVVRFCFSLQKNDGLEIEWKDSQRYDVRFYNFQSANSINFKGLEQEMMPAENQFKQKPYNNGAINLNIAKYGKEGKKLRKFNTDILGKKHYLFYEKEPKNIIK
>NZ_CABHGG010000001.1|WP_002364071.1|530596_531481_-|ABC-transporter-permease
MIRTFFSHLFESIKSLKRNGWMTVASASAVTITLVLVGIFMGVIFNATKLADDIEKNVTVSVFVDIGTKQNEMKTLEKQLKGLDNVEDISYSNKDQQLKKIQEQMGDAWNLFEGDSNPLYDVYYVRAKTPEDTKDIAKQAAKFPSVFKADYGGVNSDKIFKIAQTVRTWGLAAAALLLFVAVFLISNTIRITILSRQKEIQIMRLVGAKNSFIRWPFFLEGAWIGLIGAIVPVIIMTLGYHQVYNMFNPQLLRSNYSLIRPEDFIWKVNLLMIATGMIIGSLGSVISMRRFLKI
>NZ_CABHGG010000001.1|WP_002361935.1|531473_532160_-|cell-division-ATP-binding-protein-FtsE
MIEMKDVMKKYSNGTTAIRNISVEIDQGEFVYVVGPSGAGKSTFIRLMYREEKATKGNLTVAGHDLMKIKNKEVPYLRREIGIVFQDYKLLPKKTVYENVAYAMQVIGRRPREIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLIADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRDQVEGEYGYDD
>NZ_CABHGG010000001.1|WP_111997025.1|532265_533367_-|peptide-chain-release-factor-2
MENPEIRTLLDEMTQKITSFRRSLDLDQLEEDIAEAENRMGEPGFWDNTETAQKLINETNSLKEKYQQFHQLSEELDELTVMFELQQEEYDAEIQEELEERIHLLQERLTTYELSLLLNEPYDHNNALIELHPGAGGTESQDWGSMLLRMYTRWAESHGFQVETLDYQAGDEAGIKSVTLLIKGYNAYGYLKSEKGVHRLVRISPFDSAKRRHTSFCSVDVMPELDDTIEIAINPDDLKIDTYRASGAGGQHINKTESAVRITHIPTGTVVASQAQRSQLKNREQAMSMLKAKLYQLEMEKKAQEAASLRGEQMEIGWGSQIRSYVFHPYSMVKDHRTNYETGNVQAVMDGDLDGFIDAYLKQRLS
>NZ_CABHGG010000001.1|WP_002420121.1|533443_535981_-|preprotein-translocase-subunit-SecA
MANFLKKMIENDKKELRRLEKIADKIDAHASAMEQLSDEQLREKTDEFKARYQKGETLDELLPEAFAVVREAAKRVLGLFPYRVQLMGGIVLHDGNIPEMRTGEGKTLTATMPVYLNALSGEGVHVVTVNEYLATRDSNEMGELYNFLGLSVGLNINSKSSDEKREAYNCDITYSTNNELGFDYLRDNMVVYRSQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKSTALYTRADNFVKRLKEDEDYKIDIQSKTIGLTEAGIEKAEETFGLDNLYDIENTALTHHLDQALRANYIMLLDIDYVVQDNKVLIVDQFTGRIMDGRRYSDGLHQAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVIQIPTNRPIIRDDRPDLLYPTLESKFNAVVEDIKERYHKGQPVLVGTVAVETSELLSDKLNAAKIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVLELGGLAVIGTERHESRRIDNQLRGRAGRQGDPGVSQFYLSLEDDLMKRFGSERIKTFLERMNVQEEDAVIQSKMFTRQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYAQRQEVIMEENDLSDVLMGMVKRTIGRVVDSHTQLEKEEWNLDGIVDFAASTLVHEDTISKKDLENKSAEEIKDYLVARAQEVFEEKSQQLNGQEQLLEFEKVVILRVVDTKWTDHIDAMDQLRQSVGLRAYGQNNPLVEYQTEGYSMYNNMVGSIEYEVTRLFMKSEIRQNVQREQVAQGQAEHPETEQDAAAQSNTSAKRQPVRVDKKVGRNDLCPCGSGKKFKNCHGRNA
>NZ_CABHGG010000001.1|WP_002357293.1|536236_536788_-|ribosome-associated-translation-inhibitor-RaiA
MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDSPEATVHVNLKVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRETGRNNTKAAVFLVGEETEETPSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFEDAETNGTSIVYRRKDGKYGLIETD
>NZ_CABHGG010000001.1|WP_010715263.1|536926_537613_-|ComF-family-protein
MDCKNCASPIRLEITLKMLLRFKKWARPSLCQHCQAKFQKLPMTGTCFGCGRVSQEYYCLDCRRWQLLYPEYSFHNAALFHYDEGMQEWMERYKFQGDYRLRMCFNEEINFYFQQQSADYIIPVPLSEKRMQERGFNQVIGLLEAADVPYSPFLIRKEENVPQSKKTRKERMQLQQPFAIQKENQEKLKNCSIILVDDIYTTGRTLFHAAAVINDCYPKSLNTFTLAR

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Crispr_ID: NZ_CABHGG010000001_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CABHGG010000001_2

970540-970653

Orphan

Consensus_repeat	Method
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CABHGG010000001_2

>merge|NZ_CABHGG010000001|2|970540-970653|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTACTGTTCATCATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAGACAACGTTCCCTTTGGTCACCTTGTGCTGTTC

>NZ_CABHGG010000001|2|2|970540-970653|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC	ATCATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAG
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CABHGG010000001.1\|WP_002382760.1\|978488_979346_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NZ_CABHGG010000001.1\|WP_002356760.1\|962393_963275_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CABHGG010000001.1\|WP_002370425.1\|967328_969413_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CABHGG010000001.1\|WP_002382768.1\|966131_967064_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CABHGG010000001.1\|WP_002387080.1\|977949_978390_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CABHGG010000001.1\|WP_002379669.1\|969414_970323_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NZ_CABHGG010000001.1\|WP_002356745.1\|973269_973749_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CABHGG010000001.1\|WP_002356741.1\|977132_977582_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CABHGG010000001.1\|WP_002356743.1\|975975_976998_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NZ_CABHGG010000001.1\|WP_002382770.1\|964806_965583_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CABHGG010000001.1\|WP_002356740.1\|977607_977784_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CABHGG010000001.1\|WP_002356759.1\|963380_964166_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CABHGG010000001.1\|WP_002382765.1\|971091_971886_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CABHGG010000001.1\|WP_002382764.1\|972884_973286_-\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NZ_CABHGG010000001.1\|WP_002382763.1\|973748_975947_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NZ_CABHGG010000001.1\|WP_002382772.1\|964349_964787_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CABHGG010000001.1\|WP_010715369.1\|965689_965965_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NZ_CABHGG010000001.1\|WP_002356761.1\|961410_962133_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CABHGG010000001.1\|WP_002359745.1\|971968_972871_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CABHGG010000001.1\|WP_002382766.1\|967097_967289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104

Protein	Function_ID	Function_description	E-value
NZ_CABHGG010000001.1\|WP_002382760.1\|978488_979346_+\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	4.76001e-139
NZ_CABHGG010000001.1\|WP_002356760.1\|962393_963275_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
NZ_CABHGG010000001.1\|WP_002370425.1\|967328_969413_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CABHGG010000001.1\|WP_002382768.1\|966131_967064_+\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.11513e-134
NZ_CABHGG010000001.1\|WP_002387080.1\|977949_978390_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	4.90593e-35
NZ_CABHGG010000001.1\|WP_002379669.1\|969414_970323_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CABHGG010000001.1\|WP_002356745.1\|973269_973749_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	4.17563e-61
NZ_CABHGG010000001.1\|WP_002356741.1\|977132_977582_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NZ_CABHGG010000001.1\|WP_002356743.1\|975975_976998_-\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	3.84494e-145
NZ_CABHGG010000001.1\|WP_002382770.1\|964806_965583_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.88552e-72
NZ_CABHGG010000001.1\|WP_002356740.1\|977607_977784_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NZ_CABHGG010000001.1\|WP_002356759.1\|963380_964166_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.78425e-167
NZ_CABHGG010000001.1\|WP_002382765.1\|971091_971886_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.19301e-71
NZ_CABHGG010000001.1\|WP_002382764.1\|972884_973286_-\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	5.07031e-42
NZ_CABHGG010000001.1\|WP_002382763.1\|973748_975947_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	1.69258e-159
NZ_CABHGG010000001.1\|WP_002382772.1\|964349_964787_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.78953e-30
NZ_CABHGG010000001.1\|WP_010715369.1\|965689_965965_+\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	4.22972e-27
NZ_CABHGG010000001.1\|WP_002356761.1\|961410_962133_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NZ_CABHGG010000001.1\|WP_002359745.1\|971968_972871_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	0
NZ_CABHGG010000001.1\|WP_002382766.1\|967097_967289_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	8.4601e-06

>NZ_CABHGG010000001.1|WP_002379669.1|969414_970323_-|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>NZ_CABHGG010000001.1|WP_002370425.1|967328_969413_-|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFKVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NZ_CABHGG010000001.1|WP_002382766.1|967097_967289_-|hypothetical-protein
MSETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NZ_CABHGG010000001.1|WP_002382768.1|966131_967064_+|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQRIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>NZ_CABHGG010000001.1|WP_010715369.1|965689_965965_+|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAMAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NZ_CABHGG010000001.1|WP_002382770.1|964806_965583_-|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLVEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFQNNQ
>NZ_CABHGG010000001.1|WP_002382772.1|964349_964787_-|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEDQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDVLSLAVYRENQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NZ_CABHGG010000001.1|WP_002356759.1|963380_964166_-|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NZ_CABHGG010000001.1|WP_002356760.1|962393_963275_-|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NZ_CABHGG010000001.1|WP_002356761.1|961410_962133_-|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK
>NZ_CABHGG010000001.1|WP_002382765.1|971091_971886_-|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSRYSGVLCEKHWHLDEQRYHADPRAIHFIRLFSQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEKET
>NZ_CABHGG010000001.1|WP_002359745.1|971968_972871_-|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NZ_CABHGG010000001.1|WP_002382764.1|972884_973286_-|diacylglycerol-kinase-family-protein
MALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NZ_CABHGG010000001.1|WP_002356745.1|973269_973749_-|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGEDELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NZ_CABHGG010000001.1|WP_002382763.1|973748_975947_-|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVTFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICAGAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NZ_CABHGG010000001.1|WP_002356743.1|975975_976998_-|PhoH-family-protein
MWYHCKGLYNKGDGRFLTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NZ_CABHGG010000001.1|WP_002356741.1|977132_977582_-|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NZ_CABHGG010000001.1|WP_002356740.1|977607_977784_-|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NZ_CABHGG010000001.1|WP_002387080.1|977949_978390_-|transcriptional-repressor
MAMAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>NZ_CABHGG010000001.1|WP_002382760.1|978488_979346_+|kinase/pyrophosphorylase
MTISEEKKCVTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CABHGG010000001_1	1.8\|523985\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523985-524014	30	NC_028671	Enterococcus phage vB_EfaS_IME197, complete genome	35474-35503	1	0.967
NZ_CABHGG010000001_1	1.1\|523523\|30\|NZ_CABHGG010000001\|CRT	523523-523552	30	GQ478088	Enterococcus phage phiFL4A, complete genome	32111-32140	5	0.833
NZ_CABHGG010000001_1	1.8\|523985\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523985-524014	30	NC_019735	Crinalium epipsammum PCC 9333 plasmid pCRI9333.04, complete sequence	24646-24675	5	0.833
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NC_017296	Clostridium acetobutylicum EA 2018 plasmid pEA2018, complete sequence	116856-116885	6	0.8
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NC_015686	Clostridium acetobutylicum DSM 1731 plasmid pSMBa, complete sequence	116856-116885	6	0.8
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NC_001988	Clostridium acetobutylicum ATCC 824 plasmid pSOL1, complete sequence	116856-116885	6	0.8
NZ_CABHGG010000001_1	1.9\|524051\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	524051-524080	30	NZ_CP030843	Acidisarcina polymorpha strain SBC82 plasmid pACPOL4, complete sequence	149870-149899	6	0.8
NZ_CABHGG010000001_1	1.9\|524051\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	524051-524080	30	NC_031034	Bacillus phage SalinJah, complete genome	89666-89695	6	0.8
NZ_CABHGG010000001_1	1.2\|523589\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523589-523618	30	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	66108-66137	7	0.767
NZ_CABHGG010000001_1	1.2\|523589\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523589-523618	30	MF417933	Uncultured Caudovirales phage clone 7S_4, partial genome	2479-2508	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP009218	Rickettsiales bacterium Ac37b plasmid 1, complete sequence	1974-2003	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	62746-62775	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	64983-65012	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	75699-75728	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP018030	Alteromonas mediterranea strain RG65 plasmid MRG65-300, complete sequence	108727-108756	7	0.767
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	108184-108213	7	0.767
NZ_CABHGG010000001_1	1.6\|523853\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523853-523882	30	NC_015561	Hoyosella subflava DQS3-9A1 plasmid pAS9A-2, complete sequence	5014-5043	7	0.767
NZ_CABHGG010000001_1	1.7\|523919\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523919-523948	30	NZ_CP028250	Pediococcus acidilactici strain SRCM102732 plasmid unnamed1, complete sequence	19389-19418	7	0.767
NZ_CABHGG010000001_1	1.2\|523589\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523589-523618	30	NZ_CP020374	Shewanella khirikhana strain TH2012 plasmid pSTH1, complete sequence	152-181	8	0.733
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	NC_048758	Serratia phage Parlo, complete genome	38351-38380	8	0.733
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	MH412654	Synechococcus phage S-T4, complete genome	27670-27699	8	0.733
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	LC576631	Staphylococcus phage vB_SauH_DELF3 DNA, complete sequence	112613-112642	9	0.7
NZ_CABHGG010000001_1	1.5\|523787\|30\|NZ_CABHGG010000001\|CRT,PILER-CR,CRISPRCasFinder	523787-523816	30	MH595538	Vibrio phage BONAISHI, complete genome	64603-64632	9	0.7

1. spacer 1.8|523985|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_028671 (Enterococcus phage vB_EfaS_IME197, complete genome) position: , mismatch: 1, identity: 0.967

gattgagggaattttgattgatgctggtta	CRISPR spacer
gatcgagggaattttgattgatgctggtta	Protospacer
***.**************************

2. spacer 1.1|523523|30|NZ_CABHGG010000001|CRT matches to GQ478088 (Enterococcus phage phiFL4A, complete genome) position: , mismatch: 5, identity: 0.833

gagttcgtacatccaacctacttccttatt	CRISPR spacer
aagttcgtacatccaacctacctcctatct	Protospacer
.********************.****  .*

3. spacer 1.8|523985|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_019735 (Crinalium epipsammum PCC 9333 plasmid pCRI9333.04, complete sequence) position: , mismatch: 5, identity: 0.833

gattgagggaattttgattgatgctggtta	CRISPR spacer
tattgaggaaattctgattgatgctggtat	Protospacer
 *******.****.**************

4. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_017296 (Clostridium acetobutylicum EA 2018 plasmid pEA2018, complete sequence) position: , mismatch: 6, identity: 0.8

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagtagaagaatttatcaaggctttataca	Protospacer
 **.*************** ****.* * *

5. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_015686 (Clostridium acetobutylicum DSM 1731 plasmid pSMBa, complete sequence) position: , mismatch: 6, identity: 0.8

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagtagaagaatttatcaaggctttataca	Protospacer
 **.*************** ****.* * *

6. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_001988 (Clostridium acetobutylicum ATCC 824 plasmid pSOL1, complete sequence) position: , mismatch: 6, identity: 0.8

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagtagaagaatttatcaaggctttataca	Protospacer
 **.*************** ****.* * *

7. spacer 1.9|524051|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP030843 (Acidisarcina polymorpha strain SBC82 plasmid pACPOL4, complete sequence) position: , mismatch: 6, identity: 0.8

accttgttgaagaacggtgaaatagcttta---	CRISPR spacer
accttgttgaagaacgatggaat---tttgaaa	Protospacer
****************.**.***   ***.

8. spacer 1.9|524051|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_031034 (Bacillus phage SalinJah, complete genome) position: , mismatch: 6, identity: 0.8

accttgttgaagaacggtgaaatagcttta---	CRISPR spacer
aacttgttgaagaacggcgaaatg---ttaaac	Protospacer
* ***************.*****.   ***

9. spacer 1.2|523589|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 7, identity: 0.767

tattgggcaacgattctttctttaatccct	CRISPR spacer
tattgggctacaattctttctttacccata	Protospacer
******** **.************ .* .

10. spacer 1.2|523589|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to MF417933 (Uncultured Caudovirales phage clone 7S_4, partial genome) position: , mismatch: 7, identity: 0.767

tattgggcaacgattctttctttaatccct	CRISPR spacer
ttaagaacaacgtttctttctttattccct	Protospacer
*   *..***** *********** *****

11. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP009218 (Rickettsiales bacterium Ac37b plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
aagcagaaaaatttatcaatgattcctctg	Protospacer
********.************ ***    .

12. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagcagatgaaattatcaatgcttacaacg	Protospacer
 ****** *** ************  ** .

13. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagcagatgaaattatcaatgcttacaacg	Protospacer
 ****** *** ************  ** .

14. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagcagatgaaattatcaatgcttacaacg	Protospacer
 ****** *** ************  ** .

15. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP018030 (Alteromonas mediterranea strain RG65 plasmid MRG65-300, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
gatcaaaagaagttatcaatgcttcagtat	Protospacer
.* **.***** **************. *

16. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 7, identity: 0.767

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagcagatgaaattatcaatgcttacaacg	Protospacer
 ****** *** ************  ** .

17. spacer 1.6|523853|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_015561 (Hoyosella subflava DQS3-9A1 plasmid pAS9A-2, complete sequence) position: , mismatch: 7, identity: 0.767

aagaatgggaccagatcggctggggaacga	CRISPR spacer
ccaaatgggaccagctcggctgggaaacag	Protospacer
  .*********** *********.***..

18. spacer 1.7|523919|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP028250 (Pediococcus acidilactici strain SRCM102732 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tactaatcgttcattcaatgcttgctcgtt	CRISPR spacer
attcaatcgtttattcaatgcctgctcgat	Protospacer
  ..*******.*********.****** *

19. spacer 1.2|523589|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020374 (Shewanella khirikhana strain TH2012 plasmid pSTH1, complete sequence) position: , mismatch: 8, identity: 0.733

tattgggcaacgattctttctttaatccct	CRISPR spacer
aggagggcaacgatgctgtctttaatctgt	Protospacer
 .  ********** ** *********. *

20. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to NC_048758 (Serratia phage Parlo, complete genome) position: , mismatch: 8, identity: 0.733

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cacaggaagaatttatcaaggcttcaaccg	Protospacer
 *  .************** *******  .

21. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to MH412654 (Synechococcus phage S-T4, complete genome) position: , mismatch: 8, identity: 0.733

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cggcagaaaaatttatcaatgctcttgtaa	Protospacer
 .******.**************.. . **

22. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to LC576631 (Staphylococcus phage vB_SauH_DELF3 DNA, complete sequence) position: , mismatch: 9, identity: 0.7

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
ctgcagaacaatttttcaatgcttcttggt	Protospacer
  ****** ***** **********  ..

23. spacer 1.5|523787|30|NZ_CABHGG010000001|CRT,PILER-CR,CRISPRCasFinder matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 9, identity: 0.7

aagcagaagaatttatcaatgcttcaaaaa	CRISPR spacer
cagcagaagaatttagcaatcctttcttct	Protospacer
 ************** **** ***.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

105262 : 125683

Enterococcus_phage(37.5%)

holin,tRNA,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002419823.1\|105262_107659_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|107683_108034_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002382232.1\|108406_108892_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_048942138.1\|108926_109409_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
WP_025192213.1\|109806_110562_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_010715123.1\|110580_111423_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	7.4e-31	31.0
WP_002360492.1\|111489_111882_+	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|111901_112309_+	RinA family phage transcriptional activator	E9LUP5	Lactobacillus_phage	3.3e-16	38.4
WP_002382237.1\|112530_112947_+	hypothetical protein	NA	NA	NA	NA
WP_010715124.1\|112959_113472_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	1.1e-34	49.4
WP_002357848.1\|113506_113866_+\|tail	tail assembly chaperone	A0A2P1JTV4	Anoxybacillus_phage	2.8e-11	36.0
WP_002382238.1\|113958_114252_+	hypothetical protein	NA	NA	NA	NA
WP_142428405.1\|114241_117175_+	hypothetical protein	A0A1U9WR55	Streptococcus_virus	8.1e-08	24.7
WP_010715126.1\|117176_118103_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	2.0e-146	78.2
WP_010715127.1\|118115_119573_+\|tail	phage tail protein	C9E2K6	Enterococcus_phage	7.2e-175	47.7
WP_016614151.1\|119605_121375_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	4.4e-142	71.8
WP_010715129.1\|121398_121794_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_002419812.1\|121912_123037_+	SH3 domain-containing protein	A0A139ZVY1	Enterococcus_phage	2.0e-76	44.3
WP_002419811.1\|123190_124111_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_002363808.1\|124136_125087_+	riboflavin biosynthesis protein RibF	A0A1V0SD03	Indivirus	1.2e-05	28.7
WP_002419810.1\|125086_125683_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	4.0e-23	37.1

DBSCAN-SWA_2

546359 : 555004

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002420113.1\|546359_546932_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.2e-25	35.1
WP_002420112.1\|546928_547960_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	6.3e-56	44.4
WP_010715270.1\|547961_549401_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.4e-50	33.0
WP_010715271.1\|549376_551596_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.5e-147	39.9
WP_002364085.1\|551592_552267_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|552267_552519_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|552532_553246_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_010715272.1\|553398_554523_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002365766.1\|554515_555004_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.4e-19	42.0

DBSCAN-SWA_3

686341 : 740056

Enterococcus_phage(38.71%)

portal,holin,tail,tRNA,integrase,plate,head,terminase

attL 701876:701894|attR 740112:740130

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002377079.1\|686341_688111_-\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA
WP_002419687.1\|688128_689430_-\|tRNA	histidine--tRNA ligase	A0A2K9L0H9	Tupanvirus	1.7e-21	24.2
WP_010715312.1\|689787_690234_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002357079.1\|690257_692471_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A142EZT7	Stenotrophomonas_phage	4.7e-08	38.4
WP_142428414.1\|692685_693438_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002419688.1\|693439_694387_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002394565.1\|694402_694897_-	DUF3013 family protein	NA	NA	NA	NA
WP_002419689.1\|694844_695534_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_002419690.1\|695650_696928_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	3.1e-105	49.6
WP_002357068.1\|697201_697534_+	hypothetical protein	NA	NA	NA	NA
WP_002383133.1\|697816_698323_+	universal stress protein	NA	NA	NA	NA
WP_002419691.1\|698427_699615_-	acetate kinase	NA	NA	NA	NA
WP_002419692.1\|699639_700647_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002419693.1\|700775_701129_-	hypothetical protein	NA	NA	NA	NA
WP_002357060.1\|701128_701563_-	ComGF family competence protein	NA	NA	NA	NA
WP_174129599.1\|701552_701924_-	type II secretion system protein	NA	NA	NA	NA
701876:701894	attL	NA	NA	NA	NA
WP_002364185.1\|702679_703621_-	ferrochelatase	NA	NA	NA	NA
WP_002357054.1\|704242_704494_-	hypothetical protein	NA	NA	NA	NA
WP_002357053.1\|704565_704766_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.6e-24	80.3
WP_002370962.1\|705602_706844_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	6.6e-169	71.7
WP_002384371.1\|706844_707078_-\|holin	phage holin	D2J020	Enterococcus_phage	1.9e-29	87.8
WP_002364191.1\|707070_707292_-	hypothetical protein	D2J019	Enterococcus_phage	2.5e-31	93.2
WP_002364192.1\|707326_707482_-	XkdX family protein	A0A1W6JQ64	Staphylococcus_phage	7.2e-09	55.6
WP_010716232.1\|707483_707804_-	hypothetical protein	NA	NA	NA	NA
WP_142428415.1\|707817_708309_-	hypothetical protein	NA	NA	NA	NA
WP_002357046.1\|708308_708596_-	collagen-like protein	NA	NA	NA	NA
WP_025192893.1\|708592_709189_-	hypothetical protein	NA	NA	NA	NA
WP_142428416.1\|709181_710063_-\|plate	BppU family phage baseplate upper protein	Q9AYV5	Lactococcus_phage	2.3e-14	28.6
WP_002410540.1\|710081_712889_-\|tail	phage tail protein	Q9AZX5	Lactococcus_phage	4.0e-145	38.7
WP_002403868.1\|712870_713605_-\|tail	tail protein	A0A1B1P761	Bacillus_phage	6.1e-13	26.1
WP_002403869.1\|713594_716492_-	tape measure protein	D7RWD8	Brochothrix_phage	5.4e-81	46.4
WP_002357039.1\|716739_717090_-	hypothetical protein	NA	NA	NA	NA
WP_002384363.1\|717142_717991_-	Ig-like domain-containing protein	A0A1D6Z291	Staphylococcus_phage	1.0e-11	51.1
WP_002357037.1\|717991_718366_-	hypothetical protein	NA	NA	NA	NA
WP_142428417.1\|718368_718767_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002357034.1\|718759_719128_-	hypothetical protein	NA	NA	NA	NA
WP_002357033.1\|719124_719469_-	hypothetical protein	NA	NA	NA	NA
WP_002357032.1\|719482_719665_-	hypothetical protein	NA	NA	NA	NA
WP_002357030.1\|719693_720581_-	DUF5309 domain-containing protein	A0A2L0HPQ0	Pseudomonas_phage	3.0e-06	21.1
WP_002389133.1\|720594_721218_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_002389265.1\|721435_721756_-	hypothetical protein	NA	NA	NA	NA
WP_002357027.1\|721820_722042_-	hypothetical protein	NA	NA	NA	NA
WP_033919452.1\|722038_723796_-\|head	head protein	A0A090D822	Clostridium_phage	5.4e-15	25.4
WP_002384358.1\|723770_725258_-\|portal	phage portal protein	A0A0S2MVB2	Bacillus_phage	1.9e-29	24.4
WP_002357024.1\|725269_726559_-\|terminase	PBSX family phage terminase large subunit	D2J001	Enterococcus_phage	1.5e-232	94.9
WP_002364203.1\|726530_727334_-\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	1.1e-127	97.0
WP_010707365.1\|727380_728103_-	hypothetical protein	D2IYV9	Enterococcus_phage	8.7e-129	99.6
WP_033789376.1\|729445_729862_-	autolysin	D2IZ17	Enterococcus_phage	9.2e-67	97.8
WP_002402491.1\|730679_731114_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	2.8e-58	80.7
WP_002372047.1\|731122_731422_-	MazG-like family protein	D2IZY1	Enterococcus_phage	1.3e-43	90.9
WP_002368214.1\|731422_731725_-	hypothetical protein	D2IZR3	Enterococcus_phage	1.6e-47	99.0
WP_002402489.1\|731721_732582_-	helix-turn-helix domain-containing protein	A0A2P1CD59	Lactobacillus_phage	3.7e-25	59.6
WP_010715320.1\|732581_732782_-	hypothetical protein	NA	NA	NA	NA
WP_002402487.1\|732786_733428_-	hypothetical protein	U5U4M2	Lactobacillus_phage	6.3e-30	36.0
WP_002402486.1\|733432_734167_-	ERF family protein	A0A1W6JNQ5	Staphylococcus_phage	1.4e-20	29.9
WP_002402485.1\|734159_734477_-	hypothetical protein	NA	NA	NA	NA
WP_002402484.1\|734672_735011_-	hypothetical protein	NA	NA	NA	NA
WP_002378465.1\|735047_735257_-	hypothetical protein	D2IZ57	Enterococcus_phage	8.8e-18	74.2
WP_002357001.1\|735311_735500_+	YegP family protein	NA	NA	NA	NA
WP_002387270.1\|735525_736248_-	phage regulatory protein	D2IYT0	Enterococcus_phage	5.6e-43	46.5
WP_002403885.1\|736270_736582_-	hypothetical protein	NA	NA	NA	NA
WP_002383936.1\|736593_736785_-	hypothetical protein	NA	NA	NA	NA
WP_002387267.1\|737080_737422_+	helix-turn-helix transcriptional regulator	A0A1P8BMG3	Lactococcus_phage	3.2e-17	46.8
WP_002387266.1\|737426_738077_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_002387265.1\|738172_738802_+	SHOCT domain-containing protein	O48432	Lactobacillus_phage	2.7e-09	33.6
WP_048942184.1\|738907_740056_+\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	2.3e-38	30.2
740112:740130	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1162797 : 1225568

Enterococcus_phage(67.35%)

portal,holin,tail,protease,integrase,capsid,transposase,head,terminase

attL 1153974:1153991|attR 1230283:1230300

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1153974:1153991	attL	NA	NA	NA	NA
WP_002356529.1\|1162797_1163451_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002356528.1\|1163493_1164144_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_002367169.1\|1164357_1166304_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	5.5e-53	31.1
WP_002356525.1\|1166318_1166951_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002388977.1\|1167151_1168342_+	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-27	35.4
WP_142428428.1\|1168334_1170044_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_002382635.1\|1170328_1171063_-	YcjF family protein	NA	NA	NA	NA
WP_010715400.1\|1171182_1172085_-	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_002356518.1\|1172207_1173221_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010715401.1\|1173362_1174511_-	glycerate kinase	W6LM47	Streptococcus_phage	1.8e-43	36.4
WP_002359581.1\|1174532_1175825_-	GntP family permease	NA	NA	NA	NA
WP_002382632.1\|1175933_1176617_-	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_002376560.1\|1176766_1177840_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002356512.1\|1177836_1178673_-	ABC transporter permease	NA	NA	NA	NA
WP_002356510.1\|1178672_1179479_-	ABC transporter permease	NA	NA	NA	NA
WP_002356508.1\|1179497_1180583_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	7.6e-36	42.6
WP_002356507.1\|1180608_1181151_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002382628.1\|1181414_1182407_+	YhdH/YhfP family quinone oxidoreductase	NA	NA	NA	NA
WP_002382627.1\|1182422_1183196_+	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
WP_002359573.1\|1183192_1183747_+	phosphopantothenoylcysteine decarboxylase	A0A1V0S7W6	Shearwaterpox_virus	3.1e-25	37.2
WP_002356501.1\|1183750_1184386_+	ECF transporter S component	NA	NA	NA	NA
WP_002382625.1\|1184441_1185647_-	aminoacyltransferase	NA	NA	NA	NA
WP_002356499.1\|1185884_1186391_-	QueT transporter family protein	E7DN70	Pneumococcus_phage	8.5e-06	28.4
WP_002382623.1\|1186809_1187868_+	hypothetical protein	A0A0K1LKD8	Staphylococcus_phage	5.5e-07	26.1
WP_002382621.1\|1188235_1188769_-	hypothetical protein	W5R8Q1	Staphylococcus_phage	3.5e-10	28.2
WP_048942224.1\|1189821_1190565_-	CHAP domain-containing protein	S5MRN1	Enterococcus_phage	2.3e-52	56.0
WP_010715403.1\|1190578_1190839_-\|holin	phage holin	A0A1P8BMR7	Lactococcus_phage	1.1e-17	53.0
WP_002382617.1\|1190831_1191062_-	hypothetical protein	D2J019	Enterococcus_phage	3.3e-18	60.6
WP_002382616.1\|1191102_1191372_-	hypothetical protein	NA	NA	NA	NA
WP_002382615.1\|1191374_1191728_-	hypothetical protein	NA	NA	NA	NA
WP_002382613.1\|1191706_1194631_-\|tail	phage tail protein	A7J2A7	Streptococcus_phage	4.3e-110	48.0
WP_002382612.1\|1194653_1195493_-\|tail	phage tail family protein	A7J2A6	Streptococcus_phage	2.4e-66	45.9
WP_002410279.1\|1195505_1199267_-	tape measure protein	D2IYX6	Enterococcus_phage	1.8e-20	42.2
WP_002382610.1\|1199263_1199533_-	hypothetical protein	D2IYX5	Enterococcus_phage	4.3e-17	51.1
WP_002382608.1\|1199574_1200048_-	hypothetical protein	D2IZN3	Enterococcus_phage	9.9e-33	51.2
WP_002382607.1\|1200119_1200302_-	hypothetical protein	C9E2K1	Enterococcus_phage	7.4e-13	60.3
WP_002382606.1\|1200322_1200964_-\|tail	phage major tail protein, TP901-1 family	D2IYX2	Enterococcus_phage	5.6e-71	66.5
WP_002382605.1\|1200978_1201317_-	hypothetical protein	D2IYX1	Enterococcus_phage	3.0e-31	60.4
WP_002382604.1\|1201333_1201678_-	HK97 gp10 family phage protein	D2IYX0	Enterococcus_phage	6.5e-26	51.8
WP_002382603.1\|1201674_1201956_-	hypothetical protein	D2IYW9	Enterococcus_phage	1.5e-12	42.6
WP_002382602.1\|1201952_1202324_-\|head,tail	phage head-tail connector protein	D2IYW8	Enterococcus_phage	1.0e-40	67.5
WP_002382601.1\|1202394_1203330_-	hypothetical protein	D2IYW7	Enterococcus_phage	1.5e-144	84.5
WP_142428429.1\|1203347_1203962_-	DUF4355 domain-containing protein	D2IZG1	Enterococcus_phage	3.9e-37	65.9
WP_002382598.1\|1204089_1205028_-\|capsid	minor capsid protein	D2IYW4	Enterococcus_phage	2.6e-117	71.0
WP_002382597.1\|1204993_1206529_-\|portal	phage portal protein	D2IYW2	Enterococcus_phage	1.1e-234	79.1
WP_033624181.1\|1206541_1207960_-\|terminase	phage terminase large subunit	Q9AZ66	Lactococcus_phage	7.1e-175	67.7
WP_002410282.1\|1207952_1208414_-\|transposase	transposase	D2IZL8	Enterococcus_phage	7.3e-65	78.9
WP_010715408.1\|1208444_1208675_-	hypothetical protein	NA	NA	NA	NA
WP_025188540.1\|1210384_1210801_-	autolysin	D2IZL7	Enterococcus_phage	6.0e-50	73.9
WP_002382593.1\|1211542_1212046_-	DUF1642 domain-containing protein	D2IYV1	Enterococcus_phage	9.2e-61	73.7
WP_002382592.1\|1212045_1212501_-	hypothetical protein	F0PIH9	Enterococcus_phage	1.5e-54	71.7
WP_002382591.1\|1212513_1212792_-	hypothetical protein	A0A0S2MYC7	Enterococcus_phage	1.4e-39	89.1
WP_002382589.1\|1212792_1213032_-	hypothetical protein	NA	NA	NA	NA
WP_002382588.1\|1213084_1213309_-	hypothetical protein	NA	NA	NA	NA
WP_002382587.1\|1213321_1213516_-	hypothetical protein	NA	NA	NA	NA
WP_002382586.1\|1213519_1213726_-	hypothetical protein	NA	NA	NA	NA
WP_002382585.1\|1214163_1214307_-	hypothetical protein	D2IYU4	Enterococcus_phage	1.1e-14	89.4
WP_002382584.1\|1214299_1215061_-	hypothetical protein	D2IYU3	Enterococcus_phage	3.1e-137	96.4
WP_010715409.1\|1215057_1215483_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	8.8e-65	90.1
WP_010715410.1\|1215500_1215800_-	MazG-like family protein	D2IZY1	Enterococcus_phage	1.0e-43	91.9
WP_002382580.1\|1215799_1216762_-	DUF4373 domain-containing protein	D2IYU0	Enterococcus_phage	3.1e-158	100.0
WP_002382579.1\|1216775_1217666_-	recombinase RecT	D2IYT9	Enterococcus_phage	1.6e-161	98.6
WP_002382578.1\|1217668_1218610_-	YqaJ viral recombinase family protein	D2IZK1	Enterococcus_phage	4.2e-168	94.2
WP_002410219.1\|1218682_1219060_+	hypothetical protein	D2IZX7	Enterococcus_phage	1.5e-63	100.0
WP_002382577.1\|1219021_1219297_-	hypothetical protein	D2IZX6	Enterococcus_phage	9.2e-39	100.0
WP_002382575.1\|1219391_1219619_-	hypothetical protein	D2IZX4	Enterococcus_phage	3.0e-35	100.0
WP_002382574.1\|1219618_1219942_-	hypothetical protein	D2IZX3	Enterococcus_phage	5.9e-53	100.0
WP_002382573.1\|1219984_1220170_-	hypothetical protein	D2IZX2	Enterococcus_phage	7.0e-27	100.0
WP_002382572.1\|1220160_1220355_-	hypothetical protein	D2IZ57	Enterococcus_phage	1.9e-27	92.2
WP_002364224.1\|1220408_1220591_+	YegP family protein	NA	NA	NA	NA
WP_002410221.1\|1220630_1221356_-	phage regulatory protein	A0A0P0IDD0	Lactobacillus_phage	2.2e-31	54.7
WP_002382568.1\|1221375_1221693_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_002382567.1\|1221704_1221923_-	hypothetical protein	NA	NA	NA	NA
WP_002382566.1\|1222215_1222650_+	helix-turn-helix transcriptional regulator	A0A1C8E9A4	Bacillus_phage	2.6e-27	48.6
WP_002382565.1\|1222665_1223145_+	ImmA/IrrE family metallo-endopeptidase	Q9T201	Bacillus_phage	1.7e-11	31.1
WP_002382564.1\|1223162_1223948_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_002382562.1\|1224009_1224426_+	hypothetical protein	NA	NA	NA	NA
WP_002382561.1\|1224437_1225568_+\|integrase	site-specific integrase	S5MBZ0	Brevibacillus_phage	1.4e-69	40.8
1230283:1230300	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1306347 : 1317260

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002356382.1\|1306347_1307115_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.4e-30	35.2
WP_002382497.1\|1307520_1309704_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.0e-286	66.8
WP_002356379.1\|1309736_1310333_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002362328.1\|1310377_1311496_-	DNA polymerase IV	D0R0A3	Streptococcus_phage	4.2e-13	29.1
WP_002382496.1\|1311621_1312380_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002382495.1\|1312363_1313026_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	2.0e-15	29.4
WP_002359438.1\|1313040_1313913_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
WP_002356372.1\|1314024_1314372_-	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_002356371.1\|1314364_1315204_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002382494.1\|1315320_1316271_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.0e-33	32.7
WP_002356367.1\|1316272_1316602_-	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_002382493.1\|1316621_1317260_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-54	53.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CABHGG010000009

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

53797 : 64269

Streptococcus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000615486.1\|53797_54274_-	single-stranded DNA-binding protein	A0A1S5PRS2	Streptococcus_phage	8.8e-21	49.5
WP_048947828.1\|54413_55748_-	PcfJ domain-containing protein	A8ATM0	Listeria_phage	3.3e-97	42.0
WP_002365921.1\|55744_56521_-	hypothetical protein	A8ATL9	Listeria_phage	2.5e-17	44.6
WP_001245899.1\|56682_56949_-	hypothetical protein	A0A1W6JN36	Lactococcus_phage	2.0e-22	68.2
WP_001808764.1\|56955_57138_-	hypothetical protein	NA	NA	NA	NA
WP_000238804.1\|57291_57897_-	recombinase family protein	A0A219YA40	Aeromonas_phage	3.6e-19	33.7
WP_142485171.1\|58027_61000_+\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	2.1e-197	36.6
WP_000191454.1\|61630_62311_+\|transposase	IS6-like element ISEnfa1 family transposase	A0A1X9I6C6	Streptococcus_phage	3.7e-113	88.5
WP_001028144.1\|62829_64269_-	aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CABHGG010000014

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NZ_CABHGG010000014.1|WP_033624761.1|2225_2840_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_CABHGG010000014.1|WP_002401839.1|2853_3183_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CABHGG010000014.1|WP_033624761.1|2225_2840_+|hypothetical-protein

2225_2840_+

204 aa aa

AcrIIA16

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3632\|WP_025188019.1\|AcrIIA16\|II-A\|Verified\|Enterococcus-faecalis	0.9852941176470589	1	1.0

NZ_CABHGG010000014.1|WP_002401839.1|2853_3183_+|hypothetical-protein

2853_3183_+

109 aa aa

AcrIIA17

hit_Aca_id	identity	query_coverage	hit_coverage
anti_CRISPR3633\|WP_002401839.1\|AcrIIA17\|II-A\|Verified\|Enterococcus-faecalis	1.0	1	1.0

4. NZ_CABHGG010000010

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CABHGG010000010_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CABHGG010000010_1

61225-61356

Orphan

Consensus_repeat	Method
GTTGGTTTTTCCCACTTTCGAACA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CABHGG010000010_1

>merge|NZ_CABHGG010000010|1|61225-61356|CRISPRCasFinder
GTTGGTTTTTCCCACTTTCGAACAAAGTACTGGTATTATTGGATTCTTCTGGACGTTGGTTTTTCCCACTTTCGAAAGAAACGCCGATTTTATCATGTTTATCCGAAGGTTGGTTTTTCCCACTTTCGGGAA

>NZ_CABHGG010000010|1|1|61225-61356|CRISPRCasFinder
GTTGGTTTTTCCCACTTTCGAACA	AAGTACTGGTATTATTGGATTCTTCTGGAC
GTTGGTTTTTCCCACTTTCGAAAG	AAACGCCGATTTTATCATGTTTATCCGAAG
GTTGGTTTTTCCCACTTTCGGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CABHGG010000010.1\|WP_185954125.1\|49762_50728_-\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|369832
NZ_CABHGG010000010.1\|WP_002366016.1\|57811_58966_-\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|224828
NZ_CABHGG010000010.1\|WP_002360909.1\|51829_52108_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273908
NZ_CABHGG010000010.1\|WP_002360663.1\|62039_62396_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CABHGG010000010.1\|WP_002400644.1\|54813_55119_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CABHGG010000010.1\|WP_002366018.1\|56825_57779_+\|transcriptional-regulator-PrgX	unknown	unknown	gnl\|CDD\|197775
NZ_CABHGG010000010.1\|WP_010715978.1\|58976_60614_-\|peptide-pheromone-binding-protein-TraC	unknown	unknown	gnl\|CDD\|173869
NZ_CABHGG010000010.1\|WP_002360910.1\|51034_51370_-\|DUF5406-domain-containing-protein	unknown	unknown	gnl\|CDD\|379975
NZ_CABHGG010000010.1\|WP_142958889.1\|46701_49480_-\|LPXTG-anchored-aggregation-substance	unknown	unknown	gnl\|CDD\|369832
NZ_CABHGG010000010.1\|WP_012579112.1\|52127_54803_-\|surface-exclusion-protein-SEA1/PrgA	unknown	unknown	gnl\|CDD\|275124
NZ_CABHGG010000010.1\|WP_002360664.1\|62388_63171_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CABHGG010000010.1\|WP_002365954.1\|55700_56057_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CABHGG010000010.1\|WP_002360910.1\|51034_51370_-\|DUF5406-domain-containing-protein	gnl\|CDD\|379975	pfam17400, DUF5406, Family of unknown function (DUF5406). This is a family of unknown function found in Bacteria.	1.86262e-48
NZ_CABHGG010000010.1\|WP_002366018.1\|56825_57779_+\|transcriptional-regulator-PrgX	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	1.69683e-05
NZ_CABHGG010000010.1\|WP_010715978.1\|58976_60614_-\|peptide-pheromone-binding-protein-TraC	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CABHGG010000010.1\|WP_002366016.1\|57811_58966_-\|TraB/GumN-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	2.7588e-92
NZ_CABHGG010000010.1\|WP_002360664.1\|62388_63171_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.41703e-71
NZ_CABHGG010000010.1\|WP_002360909.1\|51829_52108_-\|hypothetical-protein	gnl\|CDD\|273908	TIGR01981, UPF0051_protein_Rv1462/MT1509, FeS assembly protein SufD. This protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0.00296089
NZ_CABHGG010000010.1\|WP_142958889.1\|46701_49480_-\|LPXTG-anchored-aggregation-substance	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	1.26001e-41
NZ_CABHGG010000010.1\|WP_012579112.1\|52127_54803_-\|surface-exclusion-protein-SEA1/PrgA	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	2.16407e-43
NZ_CABHGG010000010.1\|WP_185954125.1\|49762_50728_-\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	6.40627e-06

>NZ_CABHGG010000010.1|WP_010715978.1|58976_60614_-|peptide-pheromone-binding-protein-TraC
MKKYKKFCFLGIGLLPLVLASCGTNTATKDSQDATEKKVEQVATLTAGTPVQSLDPATAVDQTSITLLANVMEGLYRLDEKNQPQPAIAAGQPKVSNNGKTYTIVIRDGAKWSDGTQITASDFVAAWQRVVDPKTASPNVELFSAIKNAKEIASGKQAKDTLAVKSIGEKTLEIELVEPTPYFTDLLSLTAYYPVQQKAIKEYGKDYGVSQKAIVTNGAFNLTNLEGVGTSDKWTISKNKEYWDQKDVSMDKINFQVVKEINTGINLYNDGQLDEAPLAGEYAKQYKKDKEYSTTLMANTMFLEMNQTGENKLLQNKNVRKAISYAIDRESLVKKLLDNGSVASVGVVPKEMAFNPVNKKDFANEKLVEFNKKQAEEYWDKAKKEIDLSKNTSLDLLVSDGEFEKKAGEFLQGQLQDSLEGLKVNVTPIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMNHGGYSNKNYDELLKDSSSKRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKIKNVLMHSIGAKYDYKKMRIEK
>NZ_CABHGG010000010.1|WP_002366016.1|57811_58966_-|TraB/GumN-family-protein
MELVRRVFIKDKEIILVGTAHISSESAELVKNIIEEENPDVVCLEWDQSRYDKYLNPDEWSDTDIVQVIKQKRLTVLISSVIYKLIQKHLAKINDSVAGAEFFEAVSSAEKVGAKIALVDRDSQVTFKRFWRLIPLRKKALLPYAFGSVLEGAEESEEEMLKLLNSENFEPIFEQLQEAYPELWKVLLVERDQYLAQKISDQEAGKIVVVIGQAHLRGVEKNLKSNQQINIKELETLPPKLWSTKVLESIIPLIIIGLLIYSFFLGVDVGKDQIMRWGIWNGGLSALFTLLALAHPLTIVTSLVFAPLATLLPMVSVGVFSAIVEATLRKPKVRDFQTMDEDIKSLKKIYKNRVLRVFLVFVLASLGGMIGNFVGGLEMFRHLI
>NZ_CABHGG010000010.1|WP_002366018.1|56825_57779_+|transcriptional-regulator-PrgX
MFKIGSVLKQIRQELNYHQIDLYSGIMSKSVYIKVEADSRPISVEELSKFSERLGVNFFEILNRAGMNTKSVNETGKEKLLISKIFTNPDLFDKNFQRIEPKRLTSLQYFSIYLGYISIAHHYNIEVPTFNKTITSDLKHLYDKRTTFFGIDYEIVSNLLNVLPYEEVSSIIKPMYPIVDSFGKDYDLTIQTVLKNALTISIMNRNLKEAQYYINQFEHLKTIKNISINGYYDLEINYLKQIYQFLTDKNIDSYLNAVNIINIFKIIGKEDIHRSLVEELTKISAKEKFTPPKEVTMYYENYVAIENNPIPEIKEQS
>NZ_CABHGG010000010.1|WP_002365954.1|55700_56057_-|hypothetical-protein
MSCFSVLRIEHVGYYGNRIIVFGQREKRKLPNATSKFVRKTKTYRIEGMFAVQIEKYFKGKKLCEREVGQVPLRSVYKQIKHVYDHNGVLIARRNSPSGPLKVTGRGMSKFLDYDKKS
>NZ_CABHGG010000010.1|WP_002400644.1|54813_55119_-|hypothetical-protein
MTKKEQNIWRKEMLALMNEDADWYRNEDTERFKRIQELAKKIETASTRQFSSHISKERFEAYQKMGLQFKEIAEEFHITTTALQQWRKDNGYPIYNKNNKK
>NZ_CABHGG010000010.1|WP_012579112.1|52127_54803_-|surface-exclusion-protein-SEA1/PrgA
MKKFASAGLSILVATGVAGIGGNEVQAAEQAQPKTPENSSTEQPAVKGTQTTEQAITEKQQQVTEKQAIVDQKQQVADTAKKEKDTIDQSVKDQQAVVDQNKDALDQSQQAVTDQQTVVDEAKKVVDEATPSAIEKAKDQVATDTQAVDDQQKVVDQAQTDVNQQQAVVDEKAKETNAAKVQNDKDQQAVTAAKQEQAKLEELAKNAEAEKAKAEKEQAAKEAELANKQKEEAKAKDQKTKDDQAVADQQTVVTTSQEKVTDAKADTAAKQADLTAKENALKDKQAATKQAQNTLDNSKEELKGHKGINLPANFTPDYYKKLSEQEKQAMEKEALALNKVFPENQADAAKATEMIDIKNPTEKQKKQMSDYFVGLLNDVREKLGLQKLKVSSQNIKFAWDNAKYTNPNEIGHDENAINKAAKENGFKEYPGQNFYENLSGGYFQPKDGKISVLDFERAAREALVDMLFNDGRMGYGHTESLLQADKTNTAIALSEENHGFSSGKIHIIGYNQSRLVDQNTYEEGSVPVFKSKETLQKEVATNQEKLATAKQAESDAQQARSASQQALNTAKTTQATAEKELSVHKATLANLQAVATKSTTNYEEKVRQTATAEKSLQQTKDQLVTINELIQNRAAVLEKAKTKVADAQAIEQTSAKVLKEKQEAQKAEENTLNSLKEVLDLAKENLNQKQVALKTSTRSLSRLENAQPTYEKALNELNKAEASVVQAQEAYENSLKSLEELKEQQAVATLAYTQAQEDLSNAKLELQQYQGVLRDLEAQQAEQQRQEALQEQVAKEQQRLEREAKQNQTLVASATSADKTPGLQQLSFSKQKEQPKAQALTHSEPRKTKQVAKAPESLPQTGEQRSIWLTIIGLFMAVGAISFKNKRRKNN
>NZ_CABHGG010000010.1|WP_002360909.1|51829_52108_-|hypothetical-protein
MNFYEIKDPYLALIAAEDEKQCLKIYTENVSDVEEEEIFYTEMRTIDKYEALKMVAESNIEDGGKLGVEEAFKQLENLKEDGELLIIDGGLL
>NZ_CABHGG010000010.1|WP_002360910.1|51034_51370_-|DUF5406-domain-containing-protein
MKNYDPNIRWGLHTIKVSFQRGVYKGFVTFVKSGNCKGLDVLGIDEEDLYDMKFKENPINFRLLGEDDNGDEWFAMTLKNDKKDELLVEDVWEELSEYIVRIEIIDFEEEK
>NZ_CABHGG010000010.1|WP_185954125.1|49762_50728_-|KxYKxGKxW-signal-peptide-domain-containing-protein
MKQQTEVKKRFKTYKAKKRWVTAPILFIGVLGVVGLATDNVQAAELDSQPGTTTVQPDNPDLQSGKETPKTAVSEEAALQKDTTSQPTKVEEVAPENKGTEQSSATPNDTINAQQPTAEAEKSAQEQPVVSPETANEPLGQPTEVAPAENEANKSTIIPKEFETPDVDKAVDEAKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDKLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMGGK
>NZ_CABHGG010000010.1|WP_142958889.1|46701_49480_-|LPXTG-anchored-aggregation-substance
QSGTLNAVFSNDPIITAFIGTNRVNGKDVKTRLTIKFFDASGKEVLPDKASPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAKSVTPKRQFNSPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNINDLNLKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAKDVTASYDLHLDQNTVTAMMKTNADGSVVLAMGYKYLLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPRSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSVYLEVQRIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAFDTVDLATGVSFFDDYDETKVSPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELRVTLPTKVKANVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWSINDKLDVKHDKFSGQWSVFANSAFVLADGTKVNKGDDISKLFTMTFDKGVVKITASQAFLDAMNLKENKHVAHSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASIVPELPKTGEKQNVLLTVAGSLAALLGLAGLGFKRRKETK
>NZ_CABHGG010000010.1|WP_002360663.1|62039_62396_-|hypothetical-protein
MSNNRGKSAAERLLGAGKEDTNPTKATTSNEKELKTTHEHIVMNKKNIEKLIKQQGNSKRNADSIRINPILANALKYWTSIGEPEKSKPDVIEETLLKSIPEEYLIKGYEMAKKQNKI
>NZ_CABHGG010000010.1|WP_002360664.1|62388_63171_-|ParA-family-protein
MARIISVANQKGGVSKTTTSINLGAALHFTFNKSVLVIDMDPQGNATDNFGFDIDGTNVPTIYEVLKDEASITEAILNYKGIDVIPADIALSSAEREFTQVGSEHRLKRVLQPIEENYDYIIIDCPPSLGILTVNAFTVSDEIIIPVEAAYFSLKGLVKLNETIETVKEYTNERLIIRGVLFTKYNERFNISKEMNKTANQISDALNVNIFDTYIRRTITVDEAQAAGSDLISFNKTSTAEDDYIQFTKEFLEKVGDLNE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5073-5102	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	602-631	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	515-544	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33709-33738	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7643-7672	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66171-66200	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12176-12205	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	503-532	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60906-60935	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92754-92783	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	503-532	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5526-5555	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43889-43918	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83505-83534	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9536-9565	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4944-4973	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	827-856	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	548-577	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	461-490	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33655-33684	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	449-478	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5472-5501	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43943-43972	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83451-83480	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4998-5027	0	1.0
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	773-802	0	1.0
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	748-777	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7697-7726	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66225-66254	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12230-12259	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60960-60989	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92808-92837	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	449-478	1	0.967
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5019-5048	2	0.933
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	694-723	2	0.933
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9482-9511	2	0.933
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31963-31992	6	0.8
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	MT711976	Streptomyces phage Coruscant, complete genome	87401-87430	7	0.767
NZ_CABHGG010000010_1	1.2\|61303\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61303-61332	30	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	586542-586571	7	0.767
NZ_CABHGG010000010_1	1.1\|61249\|30\|NZ_CABHGG010000010\|CRISPRCasFinder	61249-61278	30	JQ660954	Clostridium phage PhiS63, complete genome	22890-22919	9	0.7

1. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

2. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

3. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

4. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

5. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

6. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

7. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

8. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

9. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

10. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

11. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

12. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

13. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

14. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

15. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

16. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

17. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattattggattcttctggac	Protospacer
******************************

18. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

19. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

20. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

21. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

22. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

23. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

24. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

25. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

26. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgattttatcatgtttatccgaag	Protospacer
******************************

27. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

aagtactggtattattggattcttctggac	CRISPR spacer
aagtcctggtattattggattcttctggac	Protospacer
**** *************************

28. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**************************

29. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgctgattttatcatgtttatccgaag	Protospacer
******.***********************

30. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**************************

31. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**************************

32. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaatgccgattttatcatgtttatccgaag	Protospacer
***.**************************

33. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgctgattttatcatgtttatccgaag	Protospacer
******.***********************

34. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****..***********************

35. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****..***********************

36. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.933

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgttgattttatcatgtttatccgaag	Protospacer
*****..***********************

37. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 6, identity: 0.8

aagtactggtattattggattcttctggac	CRISPR spacer
aagtactggtattaaaggattcttcaaaat	Protospacer
**************  ********* ..*.

38. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 7, identity: 0.767

aagtactggtattattggattcttctggac	CRISPR spacer
acagagtggttttattggcttcttctggat	Protospacer
* . * **** ******* **********.

39. spacer 1.2|61303|30|NZ_CABHGG010000010|CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.767

aaacgccgattttatcatgtttatccgaag	CRISPR spacer
aaacgccgtttttatcatttttaatggtgg	Protospacer
******** ********* **** . * .*

40. spacer 1.1|61249|30|NZ_CABHGG010000010|CRISPRCasFinder matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 9, identity: 0.7

aagtactggtattattggattcttctggac	CRISPR spacer
ttgtactgatattattggtttcttcgtttt	Protospacer
  ******.********* ******    .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CABHGG010000004

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

93100 : 99952

Enterococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355360.1\|93100_93325_+	redoxin NrdH	A0A0M7REK7	Lactobacillus_phage	6.4e-14	49.3
WP_002355359.1\|93326_93704_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	D9J0S1	Brochothrix_phage	1.4e-13	34.9
WP_002355358.1\|93684_95844_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	5.9e-266	63.3
WP_002355357.1\|96044_97010_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	2.1e-130	71.3
WP_002383710.1\|97049_98336_-	TPM domain-containing protein	NA	NA	NA	NA
WP_002383709.1\|98381_98951_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	3.1e-12	28.5
WP_002355354.1\|99250_99952_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.9e-16	40.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_CABHGG010000005

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

80755 : 88674

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355794.1\|80755_81814_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002355795.1\|81813_82770_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.5e-23	33.9
WP_002383347.1\|82810_83881_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	3.8e-88	48.4
WP_002355797.1\|84279_84801_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|84914_85115_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|85175_85535_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002370721.1\|86028_86388_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002383352.1\|86455_86950_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002361365.1\|86967_87483_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	48.8
WP_002419366.1\|87498_88674_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	9.6e-85	47.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_CABHGG010000012

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4720 : 36079

Enterococcus_phage(29.41%)

portal,terminase,capsid,integrase,head,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002373990.1\|4720_7516_-\|tail	phage tail protein	D7RWE0	Brochothrix_phage	4.2e-62	69.5
WP_025187540.1\|7512_8217_-\|tail	phage tail protein	NA	NA	NA	NA
WP_048943158.1\|8222_10538_-\|tail	phage tail tape measure protein	A0A0U4IIN6	Exiguobacterium_phage	1.0e-85	52.9
WP_002369981.1\|10786_11215_-	hypothetical protein	A0A1B1P7Q6	Bacillus_phage	1.3e-28	47.7
WP_002402251.1\|11217_11874_-	hypothetical protein	A0A2H4JGN2	uncultured_Caudovirales_phage	3.2e-45	45.8
WP_002369983.1\|11870_12227_-	HK97 gp10 family phage protein	A0A1B2APW9	Phage_Wrath	2.6e-17	42.6
WP_002369984.1\|12219_12552_-	hypothetical protein	A0A2H4JFJ3	uncultured_Caudovirales_phage	4.8e-18	41.0
WP_002365100.1\|12541_12868_-\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	1.7e-20	52.4
WP_002385660.1\|12845_13136_-\|head,tail	phage gp6-like head-tail connector protein	A0A1C8E967	Bacillus_phage	2.2e-22	64.3
WP_010775228.1\|13128_14493_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	1.7e-125	67.8
WP_010730089.1\|14505_15078_-\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	2.9e-63	63.0
WP_002388450.1\|15049_16276_-\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	4.1e-147	66.3
WP_010706848.1\|16294_18022_-\|terminase	terminase large subunit	A0A2H4JDG5	uncultured_Caudovirales_phage	8.4e-255	70.7
WP_002365107.1\|18018_18471_-	hypothetical protein	A0A2H4JFK0	uncultured_Caudovirales_phage	8.0e-48	68.5
WP_010782959.1\|18718_19096_-	HNH endonuclease	A0A1B0T6C5	Bacillus_phage	1.5e-44	69.1
WP_010782960.1\|19095_19500_-	hypothetical protein	A0A1C8EAA0	Bacillus_phage	5.2e-14	38.2
WP_010711433.1\|19657_20077_-	hypothetical protein	A0A2P0ZLC0	Lactobacillus_phage	1.8e-14	38.8
WP_010782961.1\|20388_22242_-	phage/plasmid primase P4 family domain-containing protein	A0A2H4J1M0	uncultured_Caudovirales_phage	3.5e-57	29.5
WP_010782962.1\|22260_23823_-	hypothetical protein	A0A139ZW20	Enterococcus_phage	3.4e-21	25.4
WP_010716248.1\|23968_24778_-	hypothetical protein	A0A288TXV9	Enterococcus_phage	9.5e-84	72.5
WP_002407621.1\|24802_25315_-	hypothetical protein	A0A1B0Y6E2	Lactobacillus_phage	6.7e-27	41.1
WP_010716249.1\|25353_26271_-	AAA family ATPase	A0A0A1ENB5	Lactobacillus_phage	7.7e-74	56.0
WP_002407623.1\|26267_26486_-	hypothetical protein	NA	NA	NA	NA
WP_010716250.1\|26487_27399_-	YqaJ viral recombinase family protein	A0A2H4JA52	uncultured_Caudovirales_phage	9.9e-13	29.4
WP_010716251.1\|27411_27654_-	hypothetical protein	NA	NA	NA	NA
WP_010716252.1\|27654_27888_-	hypothetical protein	D2J045	Enterococcus_phage	1.1e-13	57.8
WP_025192876.1\|27877_29092_-	DEAD/DEAH box helicase	I7AUH0	Enterococcus_phage	1.3e-28	28.8
WP_002418647.1\|29081_29375_-	VRR-NUC domain-containing protein	A0A2K9VEN8	Gordonia_phage	3.5e-12	43.6
WP_010782964.1\|29377_30055_-	DUF1642 domain-containing protein	D2J034	Enterococcus_phage	1.1e-90	71.2
WP_142485129.1\|30165_30351_-	hypothetical protein	D2J033	Enterococcus_phage	4.7e-23	94.7
WP_010714172.1\|30361_30541_-	hypothetical protein	A0A0S2MY96	Enterococcus_phage	8.4e-17	76.8
WP_010714171.1\|30537_30756_-	aspartate decarboxylase	NA	NA	NA	NA
WP_010782966.1\|30761_30962_-	hypothetical protein	D2J031	Enterococcus_phage	5.1e-31	97.0
WP_002365131.1\|30999_31269_-	hypothetical protein	NA	NA	NA	NA
WP_010776102.1\|31344_31659_+	hypothetical protein	A0A1B0YA89	Lactobacillus_phage	1.2e-10	41.2
WP_122634212.1\|31914_32097_+	hypothetical protein	NA	NA	NA	NA
WP_104802090.1\|32088_32391_-	hypothetical protein	NA	NA	NA	NA
WP_104802091.1\|32403_32586_-	hypothetical protein	NA	NA	NA	NA
WP_010782967.1\|32877_33213_+	helix-turn-helix transcriptional regulator	D2IZV9	Enterococcus_phage	1.2e-29	60.4
WP_002373917.1\|33231_33576_+	ImmA/IrrE family metallo-endopeptidase	D2IZV8	Enterococcus_phage	7.9e-48	80.7
WP_010706860.1\|33604_34003_+	hypothetical protein	NA	NA	NA	NA
WP_010773827.1\|34020_34743_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	3.9e-20	51.0
WP_142485127.1\|34897_36079_+\|integrase	tyrosine-type recombinase/integrase	Q938N9	Temperate_phage	3.5e-50	35.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage