CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP012345	Salmonella enterica subsp. enterica serovar Choleraesuis str. ATCC 10708 plasmid pCFSAN000679_01, complete sequence	0 crisprs	cas14j	0	0	1	0
CP012344	Salmonella enterica subsp. enterica serovar Choleraesuis str. ATCC 10708, complete genome	2 crisprs	PD-DExK,WYL,cas3,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3,DEDDh,DinG,cas14j	0	5	8	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34135 : 41039

Escherichia_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AKW05122.2\|34135_34558_+	protein SamA	A0A1W6JNS2	Morganella_phage	1.0e-28	51.6
AKW05121.2\|34557_35832_+	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	4.7e-154	63.7
AKW05120.2\|35913_36891_-	ParB/RepB/Spo0J family partition protein	A0A1B0V750	Salmonella_phage	5.2e-84	53.2
AKW05119.1\|36887_38093_-	ParA family protein	A0A077SL49	Escherichia_phage	1.5e-162	69.3
AKW05118.2\|38507_39449_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	2.0e-72	54.3
AXQ03826.1\|39480_40047_-	DUF2913 family protein	NA	NA	NA	NA
AXQ03827.1\|40103_40439_-	hypothetical protein	NA	NA	NA	NA
AXQ03837.1\|40622_41039_-	hypothetical protein	O64348	Escherichia_phage	8.2e-07	42.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP012344

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CRISPR-Cas detection and classification

Crispr_ID: CP012344_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012344_2

900681-901136

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

7 spacers

cas3

The CRISPR arrays of CP012344_2

>merge|CP012344|2|900681-901136|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGCTCAAAACTCGGATGGTATAGGCGTGGCGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGACGCGTTAAAACTGCGCTCAATGCAGACGGCCGTGTTCCCCGCACCAGCGGGGATAAACCGGCCCGCCTGTCGCTGTACGCCGGGGCGGCATAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCATTTTTGATCATCTCCTCCAGCCTGCTGAGGTGTTCCCCGCGCTAGCGGGGATAAACCGCACTGGAGATATAGCTGCTGTCGTCATCGGGTGTGTTCCCCGCGCTAGCGGGGATAAACCGGTCAAATAAATATGAGTGAAGAAGCCAAAGCCGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCCAACGACTGGAATTTTTGCGTGTAGCCGTGTTCCCCGCGCCAACAAGGATAGCCGT

>CP012344|2|1|900681-901075|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCAAAACTCGGATGGTATAGGCGTGGCGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGTTAAAACTGCGCTCAATGCAGACGGCC
GTGTTCCCCGCACCAGCGGGGATAAACCG	GCCCGCCTGTCGCTGTACGCCGGGGCGGCATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCATTTTTGATCATCTCCTCCAGCCTGCTGAG
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CACTGGAGATATAGCTGCTGTCGTCATCGGGT
GTGTTCCCCGCGCTAGCGGGGATAAACCG	GTCAAATAAATATGAGTGAAGAAGCCAAAGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>CP012344|2|2|900681-901136|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCAAAACTCGGATGGTATAGGCGTGGCGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGTTAAAACTGCGCTCAATGCAGACGGCC
GTGTTCCCCGCACCAGCGGGGATAAACCG	GCCCGCCTGTCGCTGTACGCCGGGGCGGCATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCATTTTTGATCATCTCCTCCAGCCTGCTGAG
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CACTGGAGATATAGCTGCTGTCGTCATCGGGT
GTGTTCCCCGCGCTAGCGGGGATAAACCG	GTCAAATAAATATGAGTGAAGAAGCCAAAGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCCGT

>CP012344|2|1|900681-901136|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCAAAACTCGGATGGTATAGGCGTGGCGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCGTTAAAACTGCGCTCAATGCAGACGGCC
GTGTTCCCCGCACCAGCGGGGATAAACCG	GCCCGCCTGTCGCTGTACGCCGGGGCGGCATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCATTTTTGATCATCTCCTCCAGCCTGCTGAG
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CACTGGAGATATAGCTGCTGTCGTCATCGGGT
GTGTTCCCCGCGCTAGCGGGGATAAACCG	GTCAAATAAATATGAGTGAAGAAGCCAAAGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCAACGACTGGAATTTTTGCGTGTAGCC
GTGTTCCCCGCGCCAACAAGGATAGCCGT

Protein	Signature genes	Signature genes Name	Protein_function
CP012344.2\|AKW01405.2\|902548_903346_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
CP012344.2\|AKW01401.2\|895530_896331_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
CP012344.2\|AXQ03744.1\|903726_903897_+\|6-pyruvoyl-tetrahydrobiopterin-synthase	unknown	unknown	unknown
CP012344.2\|AXQ03310.1\|901185_902441_-\|IS3-like-element-ISSen1-family-transposase	unknown	unknown	gnl\|CDD\|222853
CP012344.2\|AKW01409.2\|907808_908543_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP012344.2\|AKW01406.1\|903435_903798_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
CP012344.2\|AKW01411.2\|910028_912692_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP012344.2\|AKW01396.1\|889759_890230_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
CP012344.2\|AKW01399.2\|891556_894256_-\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
CP012344.2\|AKW01408.2\|906020_907733_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
CP012344.2\|AKW01403.1\|898278_899577_+\|enolase	unknown	unknown	gnl\|CDD\|234617
CP012344.2\|AKW01400.2\|894335_894923_-\|fimbrial-protein-SteA	unknown	unknown	gnl\|CDD\|185169
CP012344.2\|AXQ03311.1\|909699_909924_-\|hypothetical-protein	unknown	unknown	unknown
CP012344.2\|AKW01397.2\|890244_890751_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
CP012344.2\|AKW01398.1\|890770_891544_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185177
CP012344.2\|AKW01402.1\|896558_898196_+\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
CP012344.2\|AKW01410.2\|908630_909584_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
CP012344.2\|AKW01395.2\|889226_889763_-\|fimbrial-protein-SteF	unknown	unknown	gnl\|CDD\|185168
CP012344.2\|AKW01404.2\|899712_900384_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
CP012344.2\|AKW01407.2\|904221_906021_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862

Protein	Function_ID	Function_description	E-value
CP012344.2\|AKW01405.2\|902548_903346_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.65501e-102
CP012344.2\|AKW01401.2\|895530_896331_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
CP012344.2\|AKW01407.2\|904221_906021_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
CP012344.2\|AXQ03310.1\|901185_902441_-\|IS3-like-element-ISSen1-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.55921e-41
CP012344.2\|AKW01409.2\|907808_908543_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.32701e-138
CP012344.2\|AKW01406.1\|903435_903798_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
CP012344.2\|AKW01411.2\|910028_912692_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP012344.2\|AKW01396.1\|889759_890230_-\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	1.41178e-100
CP012344.2\|AKW01399.2\|891556_894256_-\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
CP012344.2\|AKW01408.2\|906020_907733_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
CP012344.2\|AKW01403.1\|898278_899577_+\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP012344.2\|AKW01400.2\|894335_894923_-\|fimbrial-protein-SteA	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100
CP012344.2\|AKW01397.2\|890244_890751_-\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	2.99855e-105
CP012344.2\|AKW01398.1\|890770_891544_-\|fimbrial-protein	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
CP012344.2\|AKW01402.1\|896558_898196_+\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
CP012344.2\|AKW01410.2\|908630_909584_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
CP012344.2\|AKW01395.2\|889226_889763_-\|fimbrial-protein-SteF	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	3.83046e-121
CP012344.2\|AKW01404.2\|899712_900384_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	4.64989e-154

>CP012344.2|AKW01404.2|899712_900384_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALGELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>CP012344.2|AKW01403.1|898278_899577_+|enolase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>CP012344.2|AKW01402.1|896558_898196_+|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>CP012344.2|AKW01401.2|895530_896331_+|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>CP012344.2|AKW01400.2|894335_894923_-|fimbrial-protein-SteA
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>CP012344.2|AKW01399.2|891556_894256_-|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSVSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVSDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWKLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNDSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVANDGNAWLAGVKAGETLKVFWDGAAQCEASLPPTFTPELLANALLLPCKILEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>CP012344.2|AKW01398.1|890770_891544_-|fimbrial-protein
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>CP012344.2|AKW01397.2|890244_890751_-|fimbrial-protein
MTMLTRWKILVLLCGGFVTGTEAAGTKIVQLELHLVVTQPPPCTIGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>CP012344.2|AKW01396.1|889759_890230_-|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGETLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSANALTTNVPELGIELQQNGTVFPPGTSLTIDESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>CP012344.2|AKW01395.2|889226_889763_-|fimbrial-protein-SteF
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGIEDSTLPGLLALEPSSEASGFAIGVEMAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ
>CP012344.2|AXQ03310.1|901185_902441_-|IS3-like-element-ISSen1-family-transposase
MMTEFKRPQRDYPLSFKIAVVEQVEKGEMTYKQAQQRYGIQGRSTVLVWLRKYGRLDWRPGLPDLVKRKLPVAQTTIPLTPEQRIRELEEQLELANQKAEFFESVINVLKNDYGVSVGKKAARQVLTQSQAPKITVTRACQFLGHSRQAWYQYNTRCNKRQEHHAQVLDFVARTRCRQPRIGTRKLHYLLNMQADKTLNIGRDRLFNLLGEYRLLVPVKRAYHKTTNSHHRFYRHPNLLKPGPEQVTALEPEQVWVADITYLPLRSGTAYLSLVTDACSRKIVGYHVGENLQTENVVKAFRQALRRRKTTGPLVHHSDRGLQYCSVLYQSVHERNGITCSMTDGYDCYQNALAERINGILKNEFLLSRPADLEQAREIVKESVAIYNHERPHQALKYKTPDDVHQAFYRQKTVNLYQD
>CP012344.2|AKW01405.2|902548_903346_+|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGENFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEHKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>CP012344.2|AKW01406.1|903435_903798_-|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>CP012344.2|AXQ03744.1|903726_903897_+|6-pyruvoyl-tetrahydrobiopterin-synthase
MPFRHVRQAVSGFKGEIFIQRGGHDELSGNKKTAVGYRKAHFLSLTKTILRLVTGN
>CP012344.2|AKW01407.2|904221_906021_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAAEGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGMLNRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGAMDIEAADEFLSELRVERRYQRDVY
>CP012344.2|AKW01408.2|906020_907733_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFKEEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDQLIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>CP012344.2|AKW01409.2|907808_908543_+|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAEINAQLETLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLATQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP012344.2|AKW01410.2|908630_909584_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQIYEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIDYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>CP012344.2|AXQ03311.1|909699_909924_-|hypothetical-protein
MPAQFYIFFRNIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP012344.2|AKW01411.2|910028_912692_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETNGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSLLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEEACLERIGEAVEKGNCIAWIRHSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE

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Crispr_ID: CP012344_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP012344_3

918575-918908

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAAC	PILER-CR
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCNAGCGGGGATAAACNG	CRT

5 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas3

The CRISPR arrays of CP012344_3

>merge|CP012344|3|918575-918908|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCTAGCGGGGATAAACTGCTGCATATTCACGCCTCACTCCAGCACACTGGGTGTTCCCCGCGCTAGCGGGGATAAACCGTCGGATAACGTTTCGTCAGCGCGTATCATGCCGTGTTCCCCGCGCTAGCGGGGATAAACCGCTGGGAAGATTGGGCGCTTTCAATATCTTCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGACGCAATTAAATCATGACGATTTGCGCGGCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAGGGGCGTTCCGCAGTCGACAAGGGCTGAAAAATGTTCCCCGCGTCAGCGGGGATAAACAC

>CP012344|3|2|918575-918906|PILER-CR
GTGTTCCCCGCGCTAGCGGGGATAAAC	TGCTGCATATTCACGCCTCACTCCAGCACACTGG
GTGTTCCCCGCGCTAGCGGGGATAAAC	CGTCGGATAACGTTTCGTCAGCGCGTATCATGCC
GTGTTCCCCGCGCTAGCGGGGATAAAC	CGCTGGGAAGATTGGGCGCTTTCAATATCTTCCA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGACGCAATTAAATCATGACGATTTGCGCGGCCA
GTGTTCCCCGCGCCAGCGGGGATAAAC	CGAGGGGCGTTCCGCAGTCGACAAGGGCTGAAAA
ATGTTCCCCGCGTCAGCGGGGATAAAC

>CP012344|3|3|918575-918908|CRISPRCasFinder
GTGTTCCCCGCGCTAGCGGGGATAAACTG	CTGCATATTCACGCCTCACTCCAGCACACTGG
GTGTTCCCCGCGCTAGCGGGGATAAACCG	TCGGATAACGTTTCGTCAGCGCGTATCATGCC
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CTGGGAAGATTGGGCGCTTTCAATATCTTCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCAATTAAATCATGACGATTTGCGCGGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGGGCGTTCCGCAGTCGACAAGGGCTGAAAA
ATGTTCCCCGCGTCAGCGGGGATAAACAC

>CP012344|3|2|918575-918908|CRT
GTGTTCCCCGCGCTAGCGGGGATAAACTG	CTGCATATTCACGCCTCACTCCAGCACACTGG
GTGTTCCCCGCGCTAGCGGGGATAAACCG	TCGGATAACGTTTCGTCAGCGCGTATCATGCC
GTGTTCCCCGCGCTAGCGGGGATAAACCG	CTGGGAAGATTGGGCGCTTTCAATATCTTCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGCAATTAAATCATGACGATTTGCGCGGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGGGGCGTTCCGCAGTCGACAAGGGCTGAAAA
ATGTTCCCCGCGTCAGCGGGGATAAACAC

Protein	Signature genes	Signature genes Name	Protein_function
CP012344.2\|AKW01423.2\|923186_923543_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
CP012344.2\|AKW01413.2\|914258_914807_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
CP012344.2\|AKW01409.2\|907808_908543_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
CP012344.2\|AKW01411.2\|910028_912692_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP012344.2\|AKW01417.2\|917264_918185_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
CP012344.2\|AKW01420.1\|920219_921128_+\|sulfate-adenylyltransferase-subunit-2	unknown	unknown	gnl\|CDD\|235375
CP012344.2\|AKW01421.2\|921137_922577_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
CP012344.2\|AKW01428.1\|926279_927041_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
CP012344.2\|AKW01426.2\|924773_925253_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
CP012344.2\|AKW01414.2\|914820_915879_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
CP012344.2\|AXQ03311.1\|909699_909924_-\|hypothetical-protein	unknown	unknown	unknown
CP012344.2\|AKW01422.2\|922563_923169_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
CP012344.2\|AKW01425.2\|924063_924774_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
CP012344.2\|AKW01418.2\|918184_918478_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
CP012344.2\|AKW01410.2\|908630_909584_-\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
CP012344.2\|AKW01416.2\|916617_917268_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
CP012344.2\|AKW01419.1\|918922_919969_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
CP012344.2\|AKW01427.1\|925249_926299_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
CP012344.2\|AKW01424.1\|923733_924045_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
CP012344.2\|AKW01415.2\|915889_916636_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776

Protein	Function_ID	Function_description	E-value
CP012344.2\|AKW01423.2\|923186_923543_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	3.20304e-48
CP012344.2\|AKW01413.2\|914258_914807_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	2.28593e-32
CP012344.2\|AKW01409.2\|907808_908543_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.32701e-138
CP012344.2\|AKW01411.2\|910028_912692_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
CP012344.2\|AKW01417.2\|917264_918185_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.64033e-157
CP012344.2\|AKW01420.1\|920219_921128_+\|sulfate-adenylyltransferase-subunit-2	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
CP012344.2\|AKW01421.2\|921137_922577_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
CP012344.2\|AKW01428.1\|926279_927041_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
CP012344.2\|AKW01414.2\|914820_915879_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	8.05003e-136
CP012344.2\|AKW01426.2\|924773_925253_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	5.70783e-104
CP012344.2\|AKW01422.2\|922563_923169_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	3.2499e-145
CP012344.2\|AKW01425.2\|924063_924774_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	1.74134e-119
CP012344.2\|AKW01418.2\|918184_918478_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
CP012344.2\|AKW01410.2\|908630_909584_-\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
CP012344.2\|AKW01416.2\|916617_917268_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.59402e-74
CP012344.2\|AKW01419.1\|918922_919969_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
CP012344.2\|AKW01427.1\|925249_926299_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
CP012344.2\|AKW01424.1\|923733_924045_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
CP012344.2\|AKW01415.2\|915889_916636_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	6.76499e-48

>CP012344.2|AKW01418.2|918184_918478_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>CP012344.2|AKW01417.2|917264_918185_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>CP012344.2|AKW01416.2|916617_917268_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVECGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASAIFDVQTRPFAPMLSAGQTLRFNLRANPTVCKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALTWLARQGEQNGFTLRETSVDAYRQQQIRREKSRQMIQFSSVDYTGVLVLNDPVLFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>CP012344.2|AKW01415.2|915889_916636_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQASLQHPVFPLYLGRKSHPLALPLAPQLLEGSAADVLREAYRWYQDQFNALKLPLPRLQNECWWEGEHDGLTASKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>CP012344.2|AKW01414.2|914820_915879_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKNVVLGGATRLRISSQSLKRAWRTSELFEQALAGNIGIRSGRIAREAAQILIESGIDAKKAVEYVKNIANYFGKVKAEKKPKDELTNAETGQLVHISPAEFEGVKALAHRLAEEKRAPKEEELALLRKDRMAVDIAMFGRMLAEKTDFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICINKDLLVKNLNDNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMEDVLDFICA
>CP012344.2|AKW01413.2|914258_914807_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVQEDHKATLRKWHEDLQEKRGARASLRRSKTVNEACLSEGFHLLLMQTHSLWKNKADWHVTALAITAVLAAHIKFIDERQGFATQLGQKKSGDNPVMSKLRFSRLSAVKNPDELLRHLRRAVQLLDGSVNLISLADDIFRWCQEQDDLLNHHRRQQRPTEFLRIRWALEYYQAGDNEQD
>CP012344.2|AKW01411.2|910028_912692_+|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETNGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSLLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEEACLERIGEAVEKGNCIAWIRHSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE
>CP012344.2|AXQ03311.1|909699_909924_-|hypothetical-protein
MPAQFYIFFRNIYPTNNYYKFFRLFLLEEALKEASSNAFCINQNLKKTTICGESSTFCLNYRHHKGLPTINVLY
>CP012344.2|AKW01410.2|908630_909584_-|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQIYEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIDYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>CP012344.2|AKW01409.2|907808_908543_+|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAEINAQLETLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLATQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>CP012344.2|AKW01419.1|918922_919969_-|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>CP012344.2|AKW01420.1|920219_921128_+|sulfate-adenylyltransferase-subunit-2
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>CP012344.2|AKW01421.2|921137_922577_+|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVGYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPSVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>CP012344.2|AKW01422.2|922563_923169_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHHRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>CP012344.2|AKW01423.2|923186_923543_+|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFMSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIVLHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>CP012344.2|AKW01424.1|923733_924045_+|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>CP012344.2|AKW01425.2|924063_924774_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAEAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPVLVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>CP012344.2|AKW01426.2|924773_925253_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPRMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>CP012344.2|AKW01427.1|925249_926299_+|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>CP012344.2|AKW01428.1|926279_927041_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP012344_2	2.3\|900832\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	900832-900863	32	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	167172-167203	8	0.75
CP012344_2	2.3\|900832\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	900832-900863	32	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	405399-405430	8	0.75
CP012344_2	2.4\|900893\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	900893-900924	32	NZ_CP049914	Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence	234396-234427	8	0.75
CP012344_2	2.4\|900893\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	900893-900924	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	85616-85647	8	0.75
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NZ_CP022021	Listeria monocytogenes strain FDA709873-33 plasmid pCFSAN021445, complete sequence	72705-72736	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NZ_CP041212	Listeria monocytogenes strain LMP18-H2446 plasmid pCFSAN074383, complete sequence	56906-56937	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NC_022045	Listeria monocytogenes strain N1-011A plasmid, complete sequence	76500-76531	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NZ_CP014251	Listeria monocytogenes strain CFSAN010068 plasmid pCFSAN010068_01, complete sequence	30149-30180	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NC_003383	Listeria innocua Clip11262 plasmid pLI100, complete sequence	23028-23059	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NZ_MH382833	Listeria welshimeri strain 40/07 plasmid pLIS1, complete sequence	11753-11784	9	0.719
CP012344_3	3.6\|918604\|32\|CP012344\|CRISPRCasFinder,CRT	918604-918635	32	NZ_CP020834	Listeria monocytogenes strain CFSAN004330 plasmid pCFSAN004330, complete sequence	35903-35934	9	0.719
CP012344_2	2.3\|900832\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	900832-900863	32	NZ_CP053711	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence	113090-113121	10	0.688
CP012344_2	2.6\|901015\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	901015-901046	32	NZ_CP046164	Vibrio sp. THAF191c plasmid pTHAF191c_c, complete sequence	362233-362264	10	0.688
CP012344_2	2.6\|901015\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	901015-901046	32	NZ_CP046067	Vibrio sp. THAF191d plasmid pTHAF191d_c, complete sequence	110732-110763	10	0.688
CP012344_2	2.6\|901015\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	901015-901046	32	NZ_CP009266	Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence	36435-36466	10	0.688
CP012344_2	2.6\|901015\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	901015-901046	32	NZ_CP045357	Vibrio sp. THAF64 plasmid pTHAF64_b, complete sequence	217923-217954	10	0.688
CP012344_2	2.6\|901015\|32\|CP012344\|PILER-CR,CRISPRCasFinder,CRT	901015-901046	32	MN693596	Marine virus AFVG_25M324, complete genome	45600-45631	10	0.688
CP012344_3	3.10\|918848\|32\|CP012344\|CRISPRCasFinder,CRT	918848-918879	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1151729-1151760	10	0.688
CP012344_3	3.10\|918848\|32\|CP012344\|CRISPRCasFinder,CRT	918848-918879	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	661429-661460	10	0.688

1. spacer 2.3|900832|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgcctgtcgctgtacgccggggcggcata	CRISPR spacer
cgcggcctgtcgctgtccgccgcggcggggga	Protospacer
  * ************ ***** ***** . *

2. spacer 2.3|900832|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 8, identity: 0.75

gcccgcctgtcgctgtacgccggggcggcata	CRISPR spacer
cgcggcctgtcgctgtccgccgcggcggggga	Protospacer
  * ************ ***** ***** . *

3. spacer 2.4|900893|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049914 (Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

----ccatttttgatcatctcctccagcctgctgag	CRISPR spacer
ggtaaca----cgatcgtctcttccagcctgctgag	Protospacer
     **    .****.****.**************

4. spacer 2.4|900893|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 8, identity: 0.75

ccatttttgatcatctcctccagcctgctgag	CRISPR spacer
taatttttgttcatctcttccagccttatcat	Protospacer
. ******* *******.********  * *

5. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NZ_CP022021 (Listeria monocytogenes strain FDA709873-33 plasmid pCFSAN021445, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

6. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NZ_CP041212 (Listeria monocytogenes strain LMP18-H2446 plasmid pCFSAN074383, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

7. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NC_022045 (Listeria monocytogenes strain N1-011A plasmid, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

8. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NZ_CP014251 (Listeria monocytogenes strain CFSAN010068 plasmid pCFSAN010068_01, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

9. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NC_003383 (Listeria innocua Clip11262 plasmid pLI100, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

10. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NZ_MH382833 (Listeria welshimeri strain 40/07 plasmid pLIS1, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

11. spacer 3.6|918604|32|CP012344|CRISPRCasFinder,CRT matches to NZ_CP020834 (Listeria monocytogenes strain CFSAN004330 plasmid pCFSAN004330, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcatattcacgcctcactccagcacactgg--	CRISPR spacer
tgccatattcacgccacactcca--acaacgatt	Protospacer
.  ************ *******  *** .*.

12. spacer 2.3|900832|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053711 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

gcccgcctgtcgctgtacgccggggcggcata	CRISPR spacer
gcccgcctgtcgcagcacgccggtgaactgcg	Protospacer
************* *.******* * . ....

13. spacer 2.6|901015|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046164 (Vibrio sp. THAF191c plasmid pTHAF191c_c, complete sequence) position: , mismatch: 10, identity: 0.688

gtcaaataaatatgagtgaagaagccaaagcc	CRISPR spacer
ccgtagccaatatcagtgaagatgccaaagct	Protospacer
 .  *.. ***** ******** ********.

14. spacer 2.6|901015|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046067 (Vibrio sp. THAF191d plasmid pTHAF191d_c, complete sequence) position: , mismatch: 10, identity: 0.688

gtcaaataaatatgagtgaagaagccaaagcc	CRISPR spacer
ccgtagccaatatcagtgaagatgccaaagct	Protospacer
 .  *.. ***** ******** ********.

15. spacer 2.6|901015|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009266 (Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence) position: , mismatch: 10, identity: 0.688

gtcaaataaatatgagtgaagaagccaaagcc	CRISPR spacer
ccgtagccaatatcagtgaagatgccaaagct	Protospacer
 .  *.. ***** ******** ********.

16. spacer 2.6|901015|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045357 (Vibrio sp. THAF64 plasmid pTHAF64_b, complete sequence) position: , mismatch: 10, identity: 0.688

gtcaaataaatatgagtgaagaagccaaagcc	CRISPR spacer
ccgtagccaatatcagtgaagatgccaaagct	Protospacer
 .  *.. ***** ******** ********.

17. spacer 2.6|901015|32|CP012344|PILER-CR,CRISPRCasFinder,CRT matches to MN693596 (Marine virus AFVG_25M324, complete genome) position: , mismatch: 10, identity: 0.688

gtcaaataaatatgagtgaagaagccaaagcc	CRISPR spacer
taggagcaaaaatgagtgaagaagcaaaagag	Protospacer
   .*..*** ************** ****

18. spacer 3.10|918848|32|CP012344|CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 10, identity: 0.688

aggggcgttccgcagtcgacaagggctgaaaa	CRISPR spacer
ccgggcggtccgcagtcgacgagggtgaggga	Protospacer
  ***** ************.****. ....*

19. spacer 3.10|918848|32|CP012344|CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 10, identity: 0.688

aggggcgttccgcagtcgacaagggctgaaaa	CRISPR spacer
ccgggcggtccgcagtcgacgagggtgaggga	Protospacer
  ***** ************.****. ....*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1155052 : 1200275

Salmonella_phage(75.81%)

head,lysis,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXQ03333.1\|1155052_1156282_+	DUF4102 domain-containing protein	H6WRW7	Salmonella_phage	2.9e-233	94.4
AXQ03334.1\|1156259_1156544_-	excisionase Xis	H6WRW8	Salmonella_phage	1.6e-41	85.1
AXQ03335.1\|1156584_1156824_-	DUF4060 family protein	S4TR31	Salmonella_phage	2.0e-37	100.0
AXQ03336.1\|1156866_1158024_-	enterohemolysin	S4TTE8	Salmonella_phage	1.6e-217	100.0
AXQ03337.1\|1157986_1160914_-	exodeoxyribonuclease	S4TNL0	Salmonella_phage	0.0e+00	99.2
AXQ03338.1\|1161040_1161391_-	DNA breaking-rejoining protein	S4TSN6	Salmonella_phage	1.1e-60	97.4
AXQ03339.1\|1161412_1161571_-	hypothetical protein	H6WRX3	Salmonella_phage	9.0e-23	98.1
AXQ03340.1\|1161969_1162374_-	transcriptional regulator	H6WRX4	Salmonella_phage	1.6e-71	99.3
AXQ03341.1\|1162503_1162740_+	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	1.8e-38	100.0
AXQ03342.1\|1162705_1163080_+	hypothetical protein	S4TTD7	Salmonella_phage	3.0e-64	100.0
AXQ03343.1\|1164089_1164839_+	DNA replication protein DnaC	S4TNF5	Salmonella_phage	9.0e-137	99.2
AXQ03344.1\|1164849_1165197_+	DUF977 family protein	H6WRX9	Salmonella_phage	7.2e-57	96.5
AXQ03746.1\|1165544_1165808_+	hypothetical protein	A0A2H4A316	Salmonella_phage	4.5e-19	85.7
AXQ03345.1\|1165810_1166068_+	hypothetical protein	A0A192Y5W0	Salmonella_phage	1.3e-42	100.0
AXQ03346.1\|1166078_1166360_+	hypothetical protein	Q5G8V2	Enterobacteria_phage	1.5e-15	90.9
AXQ03347.1\|1166453_1166720_+	hypothetical protein	S4TNF2	Salmonella_phage	1.5e-46	100.0
AXQ03348.1\|1166874_1167114_+	DinI family protein	H6WRY5	Salmonella_phage	3.3e-37	98.7
AXQ03349.1\|1167103_1167409_+	hypothetical protein	H6WRY6	Salmonella_phage	9.8e-42	100.0
AXQ03350.1\|1167448_1168051_+	DUF1367 family protein	S4TTI0	Salmonella_phage	2.8e-109	99.0
AXQ03351.1\|1168050_1168257_+	hypothetical protein	S4TNP0	Salmonella_phage	3.5e-35	100.0
AXQ03352.1\|1168259_1168871_+	recombination protein NinG	A0A0M4RU10	Salmonella_phage	3.6e-91	96.1
AXQ03353.1\|1168867_1169008_+	YlcG family protein	A0A0M5M7B2	Salmonella_phage	7.2e-08	78.9
AXQ03354.1\|1169004_1169685_+	antiterminator	I6PDF8	Cronobacter_phage	1.2e-60	54.5
AKW03186.2\|1169805_1170492_-	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.1
AKW03185.2\|1170767_1171097_+\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	2.2e-55	99.1
AKW03184.2\|1171080_1171533_+	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
AKW04994.2\|1171550_1172000_+\|lysis	lysis protein	H6WRZ5	Salmonella_phage	2.0e-59	83.2
AXQ03355.1\|1172217_1172742_+	Rha family transcriptional regulator	G8C7W4	Escherichia_phage	9.8e-90	96.5
AXQ03356.1\|1172804_1173434_+	hypothetical protein	A0A0M3ULJ9	Salmonella_phage	2.7e-110	99.5
AXQ03357.1\|1173436_1175059_+	TerL protein	A0A0M5M1R6	Salmonella_phage	0.0e+00	99.4
AXQ03358.1\|1175058_1176528_+	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	5.8e-281	99.4
AXQ03747.1\|1176619_1177150_+\|head	phage head morphogenesis protein	A0A0M4REK0	Salmonella_phage	1.3e-84	86.9
AXQ03359.1\|1177164_1178397_+	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	9.0e-227	98.5
AXQ03360.1\|1178401_1178899_+	hypothetical protein	A0A0M4QWZ6	Salmonella_phage	3.3e-87	99.4
AXQ03361.1\|1178910_1179852_+	DUF2184 domain-containing protein	A0A0M3ULD3	Salmonella_phage	3.8e-177	99.0
AXQ03362.1\|1179893_1180262_+	hypothetical protein	A0A0M4RTX5	Salmonella_phage	5.7e-60	98.4
AXQ03363.1\|1180227_1180635_+	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.0e-70	95.6
AXQ03364.1\|1180631_1181186_+	hypothetical protein	A0A0M4S631	Salmonella_phage	1.8e-94	99.5
AXQ03365.1\|1181172_1181562_+\|head,tail	head-tail adaptor	A0A0M3ULK0	Salmonella_phage	1.1e-66	96.9
AXQ03366.1\|1181536_1182100_+	hypothetical protein	A0A0M4R331	Salmonella_phage	7.6e-80	75.3
AKW03170.2\|1182103_1183249_+	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	1.7e-163	74.5
AKW03169.2\|1183261_1183705_+	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	6.0e-56	74.5
AKW03168.2\|1183708_1184161_+	hypothetical protein	A0A0M4S6U8	Salmonella_phage	8.5e-58	77.2
AXQ03748.1\|1184172_1184349_+	lytic transglycosylase	A0A2H4J1A2	uncultured_Caudovirales_phage	2.9e-06	46.0
AXQ03367.1\|1184338_1186291_+	lytic transglycosylase catalytic	A0A0M4REK7	Salmonella_phage	4.0e-168	64.5
AXQ03368.1\|1186290_1186941_+	hypothetical protein	A0A0M3ULD5	Salmonella_phage	3.9e-56	60.6
AXQ03369.1\|1186944_1187247_+	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	2.0e-26	57.0
AXQ03370.1\|1187249_1188281_+	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	3.3e-97	51.7
AXQ03371.1\|1188277_1188613_+	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	1.1e-20	52.2
AXQ03372.1\|1188619_1188997_-	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	6.7e-16	75.4
AXQ03373.1\|1189097_1189256_+	Arc family DNA-binding protein	A0A077KAX5	Edwardsiella_phage	2.1e-11	71.4
AXQ03374.1\|1189329_1189893_+	hypothetical protein	H6WRU8	Salmonella_phage	4.5e-32	59.0
AXQ03375.1\|1189957_1190743_+	phage repressor protein	A0A2L1IV39	Escherichia_phage	1.3e-85	62.7
AKW03161.2\|1190806_1191562_+	translation initiation factor IF-2	A0A0M5M1K7	Salmonella_phage	1.6e-104	78.5
AXQ03376.1\|1191568_1191682_+	hypothetical protein	A0A0M4S639	Salmonella_phage	3.2e-14	100.0
AKW03160.2\|1191697_1192051_+	hypothetical protein	A0A0M4R339	Salmonella_phage	3.5e-59	96.6
AKW03159.2\|1192051_1193251_+	hypothetical protein	A0A0M4RD32	Salmonella_phage	9.1e-216	98.2
AKW03158.2\|1193247_1193928_+	DUF2612 domain-containing protein	A0A0M5M1K4	Salmonella_phage	7.6e-127	96.9
AXQ03377.1\|1193927_1195340_+	hypothetical protein	A0A1B0V7G4	Salmonella_phage	2.0e-206	81.9
AXQ03378.1\|1195346_1195763_+\|tail	tail fiber assembly protein	A0A1B0V844	Salmonella_phage	1.0e-65	90.3
AXQ03379.1\|1196580_1198071_-	type III secretion effector GogB	Q9MBM1	Phage_Gifsy-1	2.8e-254	98.4
AKW01681.1\|1198475_1200275_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	7.2e-23	24.9

DBSCAN-SWA_2

1661765 : 1670934

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXQ03410.1\|1661765_1662713_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.2
AKW04946.2\|1662696_1663428_+	ABC transporter permease	NA	NA	NA	NA
AKW02122.1\|1663408_1663516_-	protein YohO	NA	NA	NA	NA
AKW02123.1\|1663575_1664307_-	transcriptional regulator	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
AKW02124.2\|1664529_1666215_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.4e-278	91.1
AKW02125.2\|1666211_1666931_+	DNA-binding response regulator	NA	NA	NA	NA
AKW02126.2\|1666977_1667445_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	3.9e-74	90.3
AKW02128.1\|1668201_1668660_-	DUF1307 domain-containing protein	Q9EYF5	Enterobacteria_phage	8.4e-53	72.5
AKW02129.2\|1668900_1670934_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-55	26.9

DBSCAN-SWA_3

1936669 : 1987227

Enterobacteria_phage(25.0%)

integrase,protease,transposase,tail

attL 1952687:1952702|attR 1984848:1984863

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXQ03431.1\|1936669_1937925_-\|transposase	IS3-like element ISSen1 family transposase	Q6H9S3	Enterobacteria_phage	2.2e-18	34.5
AKW02371.1\|1938059_1939502_-	pyruvate kinase II	NA	NA	NA	NA
AKW02372.2\|1939625_1940495_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AXQ03432.1\|1940678_1940864_-	hypothetical protein	NA	NA	NA	NA
AKW02373.1\|1940836_1942312_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	2.6e-79	37.5
AKW02374.2\|1942546_1944358_+	phosphogluconate dehydratase	NA	NA	NA	NA
AKW02375.1\|1944395_1945037_+	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase	NA	NA	NA	NA
AKW02376.2\|1945136_1946315_-	phosphoribosylglycinamide formyltransferase 2	NA	NA	NA	NA
AKW02377.1\|1946445_1946736_+	DNA damage-inducible protein YebG	NA	NA	NA	NA
AKW02378.1\|1946803_1947157_+	hypothetical protein	NA	NA	NA	NA
AKW02379.2\|1947250_1947910_+	tellurite resistance TerB family protein	NA	NA	NA	NA
AKW02380.2\|1948122_1950174_+	oligopeptidase B	NA	NA	NA	NA
AKW02381.2\|1950208_1950907_-	exodeoxyribonuclease X	Q6UAU3	Klebsiella_phage	2.8e-07	40.4
AKW02382.2\|1950930_1951587_-	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
AKW02383.1\|1951694_1951925_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	2.9e-14	60.3
AKW02384.2\|1952062_1952437_+	CopC domain-containing protein YobA	NA	NA	NA	NA
AKW04952.2\|1952437_1953313_+	hypothetical protein	NA	NA	NA	NA
1952687:1952702	attL	NA	NA	NA	NA
AKW02385.1\|1953329_1953683_+	DUF2511 domain-containing protein	NA	NA	NA	NA
AKW02386.2\|1953740_1953860_+	hypothetical protein	NA	NA	NA	NA
AXQ03433.1\|1954056_1954785_-\|integrase	integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	5.6e-51	51.2
AXQ03763.1\|1954672_1955023_+	hypothetical protein	NA	NA	NA	NA
AXQ03434.1\|1956196_1956394_-	hypothetical protein	NA	NA	NA	NA
AKW03155.2\|1958235_1959036_-	hypothetical protein	NA	NA	NA	NA
AXQ03435.1\|1959969_1960314_-\|integrase	integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	1.8e-20	47.3
AXQ03436.1\|1960763_1961159_+	DUF977 family protein	NA	NA	NA	NA
AXQ03437.1\|1961445_1962576_-	GGDEF domain-containing protein	NA	NA	NA	NA
AXQ03438.1\|1962971_1964951_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	2.1e-161	46.2
AXQ03439.1\|1964968_1965160_-	hypothetical protein	NA	NA	NA	NA
AKW02393.2\|1965359_1965974_-	disulfide bond formation protein B	NA	NA	NA	NA
AKW04954.2\|1965983_1966142_-	hypothetical protein	NA	NA	NA	NA
AKW02394.2\|1966274_1967189_-	protein PagO	NA	NA	NA	NA
AXQ03764.1\|1968656_1968857_+	hypothetical protein	NA	NA	NA	NA
AKW02395.2\|1969122_1969491_-\|integrase	integrase	K7PHK0	Enterobacteria_phage	4.5e-17	38.9
AKW02397.2\|1970933_1971074_-	hypothetical protein	NA	NA	NA	NA
AXQ03440.1\|1971239_1971509_-	hypothetical protein	B6SCX2	Bacteriophage	3.1e-07	47.9
AXQ03441.1\|1971555_1971750_+	hypothetical protein	NA	NA	NA	NA
AKW02399.2\|1971878_1972298_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AKW02400.2\|1972670_1973147_-	hypothetical protein	NA	NA	NA	NA
AKW02401.2\|1973474_1973870_-	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	5.4e-16	32.8
AKW02402.2\|1974553_1975276_+	SPI-1 type III secretion system guanine nucleotide exchange factor SopE2	NA	NA	NA	NA
AKW02403.2\|1975560_1975725_+	hypothetical protein	NA	NA	NA	NA
AKW02404.2\|1975947_1976598_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.2e-57	50.5
AKW02405.1\|1976616_1976808_-	DUF1482 family protein	NA	NA	NA	NA
AKW02406.2\|1976917_1977157_-	DUF1480 family protein	NA	NA	NA	NA
AKW04955.2\|1977271_1978711_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
AKW02407.2\|1978788_1981428_-	PqiB family protein	NA	NA	NA	NA
AKW02408.2\|1981390_1982674_-	paraquat-inducible protein A	NA	NA	NA	NA
AKW02409.2\|1982715_1983300_+	GAF domain-containing protein	NA	NA	NA	NA
AKW02410.2\|1983397_1984084_+	RNA chaperone ProQ	NA	NA	NA	NA
AKW02411.2\|1984103_1986152_+\|tail,protease	tail-specific protease	A0A0R6PIZ1	Moraxella_phage	8.0e-87	33.5
1984848:1984863	attR	NA	NA	NA	NA
AKW02412.1\|1986345_1987227_+\|protease	protease HtpX	NA	NA	NA	NA

DBSCAN-SWA_4

2595895 : 2643853

Salmonella_phage(31.37%)

tail,terminase,head,tRNA,capsid,portal,transposase,integrase,holin

attL 2590781:2590800|attR 2639780:2639799

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2590781:2590800	attL	NA	NA	NA	NA
AXQ03488.1\|2595895_2596189_-	hypothetical protein	B6SD57	Bacteriophage	1.7e-19	53.5
AXQ03489.1\|2596153_2597224_+	ParB/RepB/Spo0J family plasmid partition protein	Q7Y3Y7	Yersinia_phage	1.1e-116	60.4
AXQ03490.1\|2597354_2597663_-	hypothetical protein	K7PGV5	Enterobacterial_phage	8.4e-25	55.1
AXQ03491.1\|2597665_2597908_-	DNA polymerase V	I6PD82	Cronobacter_phage	1.3e-20	57.0
AXQ03492.1\|2597962_2598199_-	hypothetical protein	S4TTF2	Salmonella_phage	5.5e-08	90.6
AXQ03493.1\|2598761_2599280_-\|tail	phage tail protein	A0A1S6KZY8	Salmonella_phage	2.9e-46	63.4
AXQ03494.1\|2599294_2601973_-	shikimate transporter	A0A1B0VFW4	Salmonella_phage	6.2e-156	67.1
AXQ03495.1\|2602026_2602269_-	hypothetical protein	NA	NA	NA	NA
AXQ03496.1\|2602307_2605670_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	80.0
AXQ03497.1\|2605732_2606380_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	7.1e-90	78.1
AXQ03498.1\|2606277_2607015_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.2e-128	84.6
AXQ03499.1\|2607021_2607720_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	3.5e-103	75.4
AXQ03500.1\|2607729_2608059_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	7.3e-43	71.3
AXQ03501.1\|2608061_2611103_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	4.5e-296	64.7
AXQ03502.1\|2611074_2611413_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	2.3e-31	62.4
AXQ03503.1\|2611409_2611805_-\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-30	56.5
AXQ03504.1\|2611855_2612602_-\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	1.9e-99	76.9
AXQ03505.1\|2612609_2613011_-\|tail	phage tail protein	Q9G0F3	Phage_Gifsy-1	8.1e-52	100.0
AXQ03506.1\|2613007_2613586_-\|tail	phage tail protein	A5LH33	Enterobacteria_phage	3.7e-82	80.2
AXQ03507.1\|2613691_2614822_+\|transposase	transposase	Q9G0F2	Phage_Gifsy-1	8.9e-213	97.9
AXQ03508.1\|2614854_2615238_-\|tail	phage tail protein	A0A0K2FJB7	Enterobacteria_phage	1.7e-27	54.7
AXQ03509.1\|2615248_2615608_-	DNA packaging protein	NA	NA	NA	NA
AXQ03510.1\|2615665_2616694_-\|capsid	minor capsid protein E	C6ZCY2	Enterobacteria_phage	1.7e-114	61.1
AXQ03511.1\|2616748_2617096_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.4e-20	53.8
AXQ03512.1\|2617108_2618605_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	9.6e-98	52.4
AXQ03513.1\|2618594_2620175_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.2e-188	62.8
AXQ03514.1\|2620171_2620375_-\|tail	phage tail protein	K7PM10	Enterobacteria_phage	1.9e-17	73.8
AXQ03515.1\|2620358_2622290_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.8e-259	65.7
AXQ03516.1\|2622261_2622807_-\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	7.4e-56	79.1
AXQ03517.1\|2623065_2623569_-	hypothetical protein	NA	NA	NA	NA
AXQ03518.1\|2623671_2624214_-	DUF2514 family protein	NA	NA	NA	NA
AXQ03519.1\|2624210_2624825_-	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	2.3e-106	91.7
AXQ03520.1\|2624824_2625106_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	2.6e-36	80.6
AXQ03521.1\|2625092_2625482_-	hypothetical protein	K7PHB9	Enterobacterial_phage	4.8e-41	72.5
AXQ03774.1\|2625982_2626402_-	hypothetical protein	A0A291AWZ9	Escherichia_phage	6.0e-58	75.5
AXQ03522.1\|2626627_2627206_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	7.1e-49	57.2
AXQ03775.1\|2627220_2628210_-	DUF968 domain-containing protein	A0A1C9IHZ5	Salmonella_phage	1.5e-192	98.8
AXQ03523.1\|2628217_2629123_-	KilA-N domain-containing protein	A0A192Y6F8	Salmonella_phage	4.8e-161	99.0
AXQ03524.1\|2629094_2629484_-	RusA family crossover junction endodeoxyribonuclease	K7PH72	Enterobacteria_phage	4.2e-61	86.8
AXQ03525.1\|2629480_2630134_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.6e-113	88.4
AXQ03526.1\|2630133_2630658_-	PerC family transcriptional regulator	Q8HA95	Salmonella_phage	2.5e-93	97.7
AXQ03527.1\|2630617_2631436_-	helix-turn-helix domain-containing protein	Q8HA96	Salmonella_phage	9.5e-132	97.4
AXQ03528.1\|2631432_2631657_-	hypothetical protein	A0A1C9II64	Salmonella_phage	3.3e-39	100.0
AXQ03776.1\|2633168_2633498_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	2.6e-40	90.8
AXQ03529.1\|2633487_2633796_+	XRE family transcriptional regulator	A0A088CD40	Shigella_phage	2.5e-45	93.1
AXQ03530.1\|2633814_2633991_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.6e-28	94.6
AXQ03531.1\|2634130_2634685_-	hypothetical protein	A0A1C9II13	Salmonella_phage	6.9e-102	100.0
AXQ03532.1\|2634713_2634938_-	XRE family transcriptional regulator	A0A1C9IHV8	Salmonella_phage	1.9e-34	100.0
AXQ03533.1\|2634876_2635062_-	amino acid permease	NA	NA	NA	NA
AXQ03534.1\|2635035_2635731_+	helix-turn-helix transcriptional regulator	Q8HAA0	Salmonella_phage	4.6e-127	99.6
AXQ03535.1\|2636065_2636263_-	hypothetical protein	NA	NA	NA	NA
AXQ03777.1\|2636214_2636700_-	hypothetical protein	A0A1C9IHY8	Salmonella_phage	8.3e-27	87.3
AXQ03536.1\|2636635_2636824_+	hypothetical protein	A0A192Y6G0	Salmonella_phage	2.1e-26	93.4
AXQ03537.1\|2636820_2637177_+	hypothetical protein	Q8HAA1	Salmonella_phage	2.5e-60	100.0
AXQ03538.1\|2637234_2638062_+	DUF2303 family protein	Q8HAA2	Salmonella_phage	5.4e-151	98.5
AXQ03539.1\|2638425_2638671_+	excisionase	NA	NA	NA	NA
AXQ03540.1\|2638651_2639779_+\|integrase	integrase	O21925	Phage_21	1.2e-121	59.2
AKW02978.2\|2639890_2641141_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-19	92.6
2639780:2639799	attR	NA	NA	NA	NA
AKW02979.2\|2641312_2641894_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
AKW02980.2\|2641890_2642220_+	DUF1311 domain-containing protein	NA	NA	NA	NA
AKW02981.1\|2642231_2642693_+	NUDIX hydrolase	NA	NA	NA	NA
AKW02982.1\|2642746_2643853_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_5

2788929 : 2886941

101

Salmonella_phage(37.29%)

lysis,tail,terminase,tRNA,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AKW03125.2\|2788929_2789610_+\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	2.8e-73	66.4
AXQ03551.1\|2789953_2790163_-	hypothetical protein	NA	NA	NA	NA
AKW03126.2\|2790228_2790888_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	3.5e-44	52.4
AKW03127.2\|2790974_2791304_+	sulfurtransferase TusE	NA	NA	NA	NA
AKW03128.1\|2791300_2791582_-	acylphosphatase	NA	NA	NA	NA
AKW03129.2\|2791630_2792410_-	AraC family transcriptional regulator	NA	NA	NA	NA
AKW03130.1\|2792435_2792984_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
AKW03131.2\|2793198_2794410_+	ribosomal RNA large subunit methyltransferase I	NA	NA	NA	NA
AKW03132.2\|2794467_2794785_+	heat shock protein HspQ	NA	NA	NA	NA
AKW03133.2\|2794829_2795246_-	CoA-binding protein	NA	NA	NA	NA
AKW03134.2\|2795416_2796079_+	DUF2057 family protein	NA	NA	NA	NA
AKW03135.1\|2796173_2796632_+	methylglyoxal synthase	NA	NA	NA	NA
AKW03136.2\|2796667_2798722_-	DNA helicase IV	A7KV33	Bacillus_phage	2.9e-20	27.6
AKW03137.1\|2798845_2799292_+	YccF domain-containing protein	NA	NA	NA	NA
AKW03138.2\|2799310_2801464_+	TIGR01666 family membrane protein	NA	NA	NA	NA
AKW03139.2\|2801450_2802056_-	TfoX family DNA transformation protein	NA	NA	NA	NA
AKW03140.2\|2802272_2802782_+	cell division inhibitor SulA	NA	NA	NA	NA
AKW04993.2\|2803138_2804191_+	porin OmpA	NA	NA	NA	NA
AKW03141.1\|2804262_2804715_-	macrodomain Ter protein	NA	NA	NA	NA
AKW03142.2\|2804900_2806661_+\|protease	Lon protease family protein	NA	NA	NA	NA
AKW03143.2\|2806729_2807248_+	beta-hydroxydecanoyl-ACP dehydratase	NA	NA	NA	NA
AKW03144.1\|2807347_2807515_-	ribosome modulation factor	NA	NA	NA	NA
AKW03145.1\|2807770_2808334_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
AKW03146.2\|2808330_2809971_-	intermembrane transport protein PqiB	NA	NA	NA	NA
AKW03147.2\|2809975_2811229_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
AKW03148.2\|2811243_2813151_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	3.2e-53	29.9
AKW03149.2\|2813163_2815272_-	ribosomal RNA large subunit methyltransferase K/L	NA	NA	NA	NA
AKW03150.2\|2815370_2816480_+	MOSC domain-containing protein	NA	NA	NA	NA
AKW03151.1\|2816476_2817019_-	cell division protein ZapC	NA	NA	NA	NA
AKW03152.2\|2817184_2818195_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
AKW03153.2\|2818402_2821015_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.4
AKW03154.2\|2821441_2821633_+	DinI family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
AXQ03552.1\|2821902_2822589_+	virulence protein	NA	NA	NA	NA
AXQ03553.1\|2822573_2822873_+	hypothetical protein	NA	NA	NA	NA
AXQ03554.1\|2822941_2823568_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	1.4e-66	63.2
AXQ03555.1\|2824215_2825094_-	SPI-2 type III secretion system effector SseI	Q9MBL9	Phage_Gifsy-2	1.5e-170	98.3
AKW03156.2\|2825658_2826240_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.7e-95	89.5
AXQ03556.1\|2826239_2828678_-\|tail	phage tail protein	A0A0K2FIZ6	Escherichia_phage	1.9e-90	63.2
AXQ03557.1\|2828731_2828974_-	hypothetical protein	NA	NA	NA	NA
AXQ03558.1\|2829012_2829936_-	DUF1983 domain-containing protein	K7PKJ2	Enterobacteria_phage	5.6e-56	76.9
AXQ03559.1\|2832433_2833138_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.4e-67	63.1
AXQ03560.1\|2833035_2833773_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.6e-114	76.1
AXQ03561.1\|2833782_2834478_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.3e-89	66.7
AXQ03562.1\|2834567_2835101_+	superoxide dismutase [Cu-Zn] SodC1	Q9MC02	Salmonella_phage	1.8e-46	54.0
AXQ03563.1\|2835217_2835715_-	Ail/OmpX	A0A1B0VBR9	Salmonella_phage	1.4e-16	36.6
AXQ03564.1\|2835813_2836146_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	2.6e-35	61.5
AXQ03779.1\|2836142_2839076_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	4.7e-258	61.1
AXQ03565.1\|2839155_2839485_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	5.0e-23	50.9
AXQ03566.1\|2839481_2839880_-\|tail	phage minor tail protein G	K7PLV8	Enterobacteria_phage	8.6e-30	56.8
AXQ03567.1\|2839925_2840675_-\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	3.7e-90	68.6
AXQ03568.1\|2840686_2841088_-\|tail	phage tail protein	K7PHM6	Enterobacterial_phage	9.0e-43	60.9
AXQ03569.1\|2841084_2841651_-\|tail	phage tail protein	Q9G063	Phage_Gifsy-2	2.1e-13	95.7
AXQ03570.1\|2841631_2841931_-	ATP-binding protein	K7PH43	Enterobacteria_phage	4.5e-15	45.1
AXQ03571.1\|2841923_2842247_-	DUF2190 family protein	K7PLV6	Enterobacteria_phage	6.6e-28	60.4
AXQ03572.1\|2843588_2843795_-	primosomal replication protein PriB/PriC domain protein	A0A1W6JT66	Pseudomonas_phage	2.9e-05	53.3
AXQ03573.1\|2843791_2845930_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	6.5e-289	72.3
AXQ03574.1\|2845886_2846420_-	DUF1441 family protein	A0A291AWV8	Escherichia_phage	3.8e-33	47.5
AXQ03781.1\|2846627_2847107_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	5.0e-56	77.7
AXQ03575.1\|2847124_2847577_-	lysozyme	A0A0M4R365	Salmonella_phage	3.9e-79	97.3
AXQ03780.1\|2847560_2847890_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	2.2e-55	99.1
AXQ03576.1\|2848165_2848852_+	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	3.9e-131	98.7
AKW03187.2\|2849212_2849662_+	hypothetical protein	NA	NA	NA	NA
AKW03188.1\|2849797_2849923_-	hypothetical protein	NA	NA	NA	NA
AKW03190.1\|2850321_2851119_-	antitermination protein	A0A0M4S661	Salmonella_phage	4.0e-151	99.6
AKW03191.2\|2851108_2851255_-	YlcG family protein	A0A0M5M7B2	Salmonella_phage	4.1e-14	85.4
AKW03192.2\|2851251_2851863_-	recombination protein NinG	A0A0M4RU10	Salmonella_phage	3.6e-91	96.1
AKW03193.2\|2851865_2852072_-	hypothetical protein	S4TNP0	Salmonella_phage	3.5e-35	100.0
AKW03194.2\|2852071_2852674_-	DUF1367 family protein	S4TTI0	Salmonella_phage	2.6e-110	100.0
AKW03195.2\|2852708_2852957_-	hypothetical protein	A0A0U2C0C8	Salmonella_phage	8.0e-42	98.8
AKW03196.1\|2853073_2853307_-	DinI family protein	H6WRY5	Salmonella_phage	5.6e-37	100.0
AXQ03577.1\|2853461_2853728_-	hypothetical protein	S4TNF2	Salmonella_phage	7.5e-46	98.9
AXQ03578.1\|2853826_2854624_-	hypothetical protein	A0A1R3Y5Q8	Salmonella_virus	4.9e-32	80.7
AXQ03579.1\|2854637_2855333_-	phage replication protein	G8C7U6	Escherichia_phage	1.5e-56	45.9
AXQ03580.1\|2855329_2856166_-	replication protein	K7PGT1	Enterobacteria_phage	3.5e-49	48.5
AKW04995.2\|2856257_2856632_-	hypothetical protein	S4TTD7	Salmonella_phage	3.3e-63	98.4
AXQ03581.1\|2856597_2856825_-	Rha family transcriptional regulator	K7PKS2	Enterobacteria_phage	1.5e-34	95.9
AKW03199.2\|2856838_2857306_+	helix-turn-helix domain-containing protein	K7PHG0	Enterobacteria_phage	7.9e-67	84.5
AXQ03582.1\|2857456_2857930_+	hypothetical protein	K7PLT9	Enterobacteria_phage	8.6e-53	58.5
AXQ03583.1\|2857926_2858859_+	hypothetical protein	K7PGT0	Enterobacteria_phage	9.6e-88	53.2
AKW03202.2\|2858891_2859098_-	hypothetical protein	K7P7I0	Enterobacteria_phage	1.6e-16	67.6
AKW03203.2\|2859496_2859655_+	hypothetical protein	H6WRX3	Salmonella_phage	9.0e-23	98.1
AKW03204.2\|2859676_2860027_+	DNA breaking-rejoining protein	S4TSN6	Salmonella_phage	1.1e-60	97.4
AKW03205.2\|2860153_2863081_+	exodeoxyribonuclease	S4TNL0	Salmonella_phage	0.0e+00	99.2
AKW03206.2\|2863043_2864201_+	enterohemolysin	S4TTE8	Salmonella_phage	1.6e-217	100.0
AKW03207.1\|2864243_2864483_+	DUF4060 family protein	S4TR31	Salmonella_phage	2.0e-37	100.0
AKW03208.1\|2864523_2864772_+	excisionase	S4TND0	Salmonella_phage	4.7e-42	100.0
AKW03209.2\|2864816_2866094_+	DUF3596 domain-containing protein	S4TSP2	Salmonella_phage	1.1e-248	99.8
AKW03210.1\|2866299_2867502_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
AKW03211.2\|2867579_2869016_-	sodium:alanine symporter family protein	NA	NA	NA	NA
AKW03212.2\|2869279_2870476_-	diaminopropionate ammonia-lyase	NA	NA	NA	NA
AKW03213.1\|2870793_2871255_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
AKW03214.2\|2871455_2872856_+\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	1.7e-80	34.9
AKW03215.2\|2873462_2874560_+	porin OmpF	Q1MVN1	Enterobacteria_phage	7.0e-98	51.5
AKW03216.1\|2874744_2875935_+	aspartate aminotransferase	NA	NA	NA	NA
AKW03217.2\|2875996_2876644_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
AKW03218.2\|2876671_2877220_-	DUF882 domain-containing protein	A0A0K1LKR7	Rhodobacter_phage	1.2e-05	33.7
AKW03219.2\|2877479_2879327_-	L,D-transpeptidase	NA	NA	NA	NA
AKW03220.2\|2879671_2884138_-	chromosome partition protein MukB	NA	NA	NA	NA
AKW03221.1\|2884137_2884842_-	chromosome partition protein MukE	NA	NA	NA	NA
AKW03222.1\|2884822_2886145_-	chromosome partition protein MukF	NA	NA	NA	NA
AKW03223.2\|2886137_2886941_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA

DBSCAN-SWA_6

2938827 : 2946140

Ralstonia_phage(16.67%)

integrase,protease

attL 2933443:2933457|attR 2944876:2944890

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2933443:2933457	attL	NA	NA	NA	NA
AXQ03587.1\|2938827_2939205_+\|integrase	integrase	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
AXQ03588.1\|2939366_2939564_+	hypothetical protein	NA	NA	NA	NA
AKW03261.2\|2939776_2942053_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.8e-165	42.3
AKW03262.1\|2942083_2942404_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
AKW03263.1\|2942727_2942949_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
AXQ03589.1\|2942903_2943098_-	hypothetical protein	NA	NA	NA	NA
AKW03264.2\|2943078_2945025_-	macrolide ABC transporter permease/ATP-binding protein MacB	G9BWD6	Planktothrix_phage	1.6e-39	43.1
2944876:2944890	attR	NA	NA	NA	NA
AKW03265.2\|2945021_2946140_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	3.1e-08	38.1

DBSCAN-SWA_7

3533864 : 3574907

Salmonella_phage(51.79%)

lysis,tail,terminase,protease,portal,coat,integrase,holin

attL 3530612:3530657|attR 3571017:3571062

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3530612:3530657	attL	NA	NA	NA	NA
AXQ03621.1\|3533864_3535625_-	hypothetical protein	I6S5Y0	Salmonella_phage	7.4e-57	85.9
AKW04937.2\|3535864_3536194_+	hypothetical protein	NA	NA	NA	NA
AKW01908.2\|3536211_3538125_-	DNA transfer protein	E7C9U6	Salmonella_phage	0.0e+00	98.7
AKW04936.2\|3538124_3539444_-	DNA transfer protein	A0A220NR03	Salmonella_phage	2.5e-214	90.2
AKW01907.2\|3539486_3540176_-	DNA transfer protein	B9UDK9	Salmonella_phage	4.3e-93	92.6
AKW01906.2\|3540178_3540634_-	DUF2824 family protein	B8K1I4	Salmonella_phage	2.0e-86	98.7
AKW01905.2\|3540633_3541272_-\|tail	phage tail protein	A0A088CPT1	Enterobacteria_phage	4.2e-87	96.2
AKW01904.2\|3541275_3542694_-	hypothetical protein	A0A2D1GM00	Escherichia_phage	1.5e-273	98.3
AKW01903.2\|3542694_3543195_-	recombinase RmuC	G8EYJ2	Enterobacteria_phage	3.6e-89	97.6
AKW01902.1\|3543172_3543409_-	hypothetical protein	A0A2D1GLK1	Escherichia_phage	1.1e-24	78.4
AKW01901.2\|3543453_3544749_-\|coat	coat protein	A0A2D1GLV2	Escherichia_phage	1.8e-241	98.8
AKW01900.2\|3544748_3545660_-	scaffolding protein	A0A2D1GLN7	Escherichia_phage	5.4e-160	99.3
AKW01899.2\|3545673_3547839_-\|portal	portal protein	A0A2D1GLJ6	Escherichia_phage	0.0e+00	99.6
AKW01898.2\|3547839_3549339_-\|terminase	terminase	G5DA96	Enterobacteria_phage	9.1e-306	99.6
AKW04935.1\|3549316_3549805_-	DNA-packaging protein	A0A0M3ULC0	Salmonella_phage	5.0e-88	99.4
AKW01896.1\|3549840_3550083_-	DUF2560 family protein	A5VW77	Enterobacteria_phage	1.3e-36	100.0
AXQ03622.1\|3550573_3551062_-	GIY-YIG nuclease family protein	K7P7S3	Enterobacteria_phage	2.7e-86	98.8
AKW04934.2\|3551267_3551705_-\|lysis	lysis protein	K7P710	Enterobacteria_phage	2.9e-71	97.9
AXQ03623.1\|3551701_3552178_-	lysozyme	K7PKV2	Enterobacteria_phage	1.6e-86	98.7
AXQ03624.1\|3552161_3552485_-\|holin	phage holin, lambda family	G5DA93	Enterobacteria_phage	1.3e-52	100.0
AXQ03625.1\|3552945_3553464_-	DUF1133 family protein	A0A1R3Y5U9	Salmonella_virus	1.6e-92	97.1
AKW01891.2\|3553460_3553640_-	hypothetical protein	A0A1V0E5I7	Salmonella_phage	1.6e-23	98.3
AKW01890.2\|3553620_3553824_-	protein ninH	A0A075B8J4	Enterobacteria_phage	7.2e-33	100.0
AKW01889.1\|3553820_3554216_-	RusA family crossover junction endodeoxyribonuclease	A0A0M4REJ2	Salmonella_phage	3.4e-71	98.5
AKW01888.2\|3554212_3554509_-	hypothetical protein	A0A0M3ULJ7	Salmonella_phage	7.5e-47	98.9
AKW01887.2\|3554471_3554648_-	NinF family protein	A0A0M4S6T3	Salmonella_phage	1.9e-26	94.8
AXQ03626.1\|3554644_3554827_-	NinE family protein	C6ZR57	Salmonella_phage	5.7e-29	100.0
AKW01886.2\|3554963_3555836_-	hypothetical protein	A0A0K2FIH3	Escherichia_phage	3.5e-177	99.7
AKW01885.2\|3555832_3556291_-	recombination protein NinB	K7PGZ3	Enterobacteria_phage	1.4e-79	98.6
AXQ03627.1\|3556346_3556625_-	hypothetical protein	B9UDH9	Salmonella_phage	2.8e-43	90.2
AXQ03628.1\|3556625_3558506_-	bifunctional DNA primase/helicase	I6S1U6	Salmonella_phage	0.0e+00	98.6
AXQ03629.1\|3558613_3559462_-	replication protein	C6ZR51	Salmonella_phage	7.0e-154	99.3
AXQ03630.1\|3559630_3559921_-	hypothetical protein	I6RSP4	Salmonella_phage	2.4e-45	100.0
AXQ03631.1\|3560029_3560245_-	XRE family transcriptional regulator	Q716D6	Shigella_phage	1.1e-18	69.0
AXQ03788.1\|3560345_3560978_+	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	2.8e-30	43.0
AXQ03632.1\|3561347_3561650_+	regulator	A0A0M3ULJ5	Salmonella_phage	5.9e-47	96.0
AXQ03633.1\|3561730_3561952_+	hypothetical protein	A0A2H4FRY7	Salmonella_phage	5.3e-37	97.3
AXQ03634.1\|3562078_3562336_+	hypothetical protein	A0A2H4FRY7	Salmonella_phage	1.5e-22	98.0
AXQ03635.1\|3562404_3562605_+	hypothetical protein	A0A2H4FQS9	Salmonella_phage	1.6e-32	100.0
AXQ03636.1\|3562796_3562970_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q76H38	Enterobacteria_phage	2.6e-23	100.0
AKW01876.1\|3562950_3563139_+	protein kil	I6S647	Salmonella_phage	3.7e-31	100.0
AKW01874.2\|3563268_3563976_+	recombinase	A0A192Y857	Salmonella_phage	4.1e-131	94.5
AXQ03637.1\|3563976_3564483_+	single-stranded DNA-binding protein	C6ZR36	Salmonella_phage	1.1e-85	92.3
AXQ03638.1\|3564491_3565040_+	3'-5' exoribonuclease	C6ZR35	Salmonella_phage	5.8e-101	95.6
AXQ03639.1\|3565057_3565351_+	DUF2856 family protein	A0A1V0E5L7	Salmonella_phage	1.9e-21	57.7
AXQ03640.1\|3565361_3565538_+	DUF2737 family protein	K7PL43	Enterobacteria_phage	3.4e-23	93.1
AXQ03641.1\|3565524_3566151_+	HNH endonuclease	K7PHS8	Enterobacteria_phage	8.1e-107	97.9
AXQ03642.1\|3566147_3566525_+	Eae protein	I6R9B7	Salmonella_phage	4.2e-58	94.3
AXQ03643.1\|3566521_3566755_+	hypothetical protein	S4TVX5	Salmonella_phage	1.2e-12	47.7
AXQ03644.1\|3566751_3567273_+	DUF262 domain-containing protein	Q8HAA5	Salmonella_phage	3.1e-96	100.0
AKW01867.2\|3567269_3567731_+	hypothetical protein	NA	NA	NA	NA
AXQ03645.1\|3567727_3568903_+	DUF551 domain-containing protein	A0A1U9HZ41	Salmonella_phage	4.2e-48	95.0
AKW01863.2\|3568973_3569609_+	Eac protein	A0A075B8I7	Enterobacteria_phage	2.5e-108	89.1
AXQ03646.1\|3569611_3569962_+	DNA-binding protein	A0A1R3Y5Z5	Salmonella_virus	3.2e-60	98.3
AXQ03789.1\|3570333_3571002_+\|integrase	site-specific integrase	A0A220NQU7	Salmonella_phage	2.3e-128	99.1
AKW03852.2\|3571207_3572458_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-98	48.2
3571017:3571062	attR	NA	NA	NA	NA
AKW03853.1\|3572469_3573573_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	6.9e-61	39.8
AKW03854.2\|3573854_3574907_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	4.8e-112	58.2

DBSCAN-SWA_8

4337696 : 4384662

Burkholderia_phage(42.86%)

tail,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AKW04498.2\|4337696_4338695_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
AKW04499.2\|4338782_4340093_-	conjugal transfer protein	NA	NA	NA	NA
AKW04500.1\|4340339_4340855_+	transcriptional regulator Zur	NA	NA	NA	NA
AKW04501.1\|4340954_4341164_-	CsbD family protein	NA	NA	NA	NA
AKW04502.2\|4341185_4341299_-	hypothetical protein	NA	NA	NA	NA
AKW04503.2\|4341295_4342621_-	MATE family efflux transporter DinF	NA	NA	NA	NA
AKW04504.1\|4342799_4343408_-	repressor LexA	Q9G0C2	Lactococcus_phage	1.0e-13	38.0
AKW04505.1\|4343516_4343885_-	diacylglycerol kinase	NA	NA	NA	NA
AKW04506.2\|4344055_4346476_+	glycerol-3-phosphate 1-O-acyltransferase	NA	NA	NA	NA
AKW04507.2\|4346574_4347447_-	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
AKW04508.2\|4347460_4347958_-	chorismate--pyruvate lyase	NA	NA	NA	NA
AKW04509.1\|4348138_4349056_-	maltose operon protein MalM	NA	NA	NA	NA
AKW04510.2\|4349219_4350578_-	maltoporin	NA	NA	NA	NA
AKW04511.1\|4350666_4351776_-	maltose/maltodextrin import ATP-binding protein MalK	Q6GZ03	Mycoplasma_phage	6.2e-17	47.2
AKW04512.1\|4352137_4353328_+	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
AKW04513.1\|4353459_4355004_+	maltose ABC transporter permease MalF	NA	NA	NA	NA
AKW04514.2\|4355018_4355909_+	maltose ABC transporter permease	NA	NA	NA	NA
AKW04515.2\|4356074_4356485_-	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
AKW04516.2\|4356627_4358724_-	YjbH domain-containing protein	NA	NA	NA	NA
AKW04518.2\|4359452_4360091_-	YjbF family lipoprotein	NA	NA	NA	NA
AKW04519.1\|4360154_4360397_-	outer membrane protein	NA	NA	NA	NA
AKW04520.2\|4360844_4362494_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
AKW04521.2\|4362838_4364188_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
AKW04522.2\|4364319_4364667_-	DNA-binding protein	Q6QIE8	Burkholderia_phage	1.7e-21	51.5
AKW04523.1\|4365241_4365529_+	hypothetical protein	Q6QIC8	Burkholderia_phage	3.0e-16	48.1
AKW04524.2\|4365531_4366137_+	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	8.4e-61	60.4
AKW04525.2\|4366149_4366464_+	hypothetical protein	Q6QIC4	Burkholderia_phage	8.3e-20	48.2
AXQ03713.1\|4366622_4367078_+	hypothetical protein	NA	NA	NA	NA
AKW04526.2\|4367074_4367272_+	hypothetical protein	Q6QIB1	Burkholderia_phage	8.6e-07	52.9
AKW04527.2\|4367261_4368689_+\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	4.0e-194	70.7
AKW04528.2\|4368688_4369213_+\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	2.8e-68	69.5
AKW04529.2\|4369264_4369582_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AXQ03714.1\|4369541_4369670_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
AKW04531.2\|4372120_4373074_+	chemotaxis protein	A4JWL1	Burkholderia_virus	7.9e-37	51.5
AKW05046.2\|4373073_4373283_+	hypothetical protein	A4JWL2	Burkholderia_virus	2.6e-17	58.8
AKW04532.2\|4373270_4374314_+	phage late control D family protein	Q6QIA2	Burkholderia_phage	1.2e-75	45.1
AKW04533.2\|4374323_4375046_+\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	3.9e-12	42.0
AXQ03715.1\|4375054_4375297_+	hypothetical protein	NA	NA	NA	NA
AKW04534.2\|4375372_4375735_+	GtrA family protein	I1TED9	Salmonella_phage	1.2e-43	70.8
AKW04535.2\|4375731_4376661_+	glycosyltransferase	S5FKN0	Shigella_phage	2.0e-149	83.4
AXQ03716.1\|4376660_4377011_+	hypothetical protein	NA	NA	NA	NA
AKW04536.2\|4377026_4378208_+	hypothetical protein	B9UDL6	Salmonella_phage	8.3e-28	27.6
AKW04537.1\|4378371_4378731_+\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	2.8e-35	64.2
AKW04538.2\|4378721_4379837_+\|plate	baseplate protein	Q6QI99	Burkholderia_phage	3.1e-101	52.2
AKW04539.1\|4379829_4380462_+\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	1.1e-23	56.4
AXQ03717.1\|4380464_4382123_+\|tail	phage tail protein	A0A0M3ULH6	Salmonella_phage	1.8e-52	40.5
AXQ03718.1\|4382129_4382744_+	DUF4376 domain-containing protein	NA	NA	NA	NA
AKW04542.2\|4382740_4383196_+	hypothetical protein	NA	NA	NA	NA
AKW04543.2\|4383933_4384662_+	hypothetical protein	A0A292GAQ8	Xanthomonas_phage	4.6e-13	28.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP012345

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP012344

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection