CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026965	Staphylococcus aureus strain FDAARGOS_2 plasmid unnamed1	0 crisprs	NA	0	0	0	0
CP026967	Staphylococcus aureus strain FDAARGOS_2 plasmid unnamed3	0 crisprs	NA	0	0	0	0
CP026966	Staphylococcus aureus strain FDAARGOS_2 plasmid unnamed2	0 crisprs	NA	0	0	0	0
CP026964	Staphylococcus aureus strain FDAARGOS_2 chromosome, complete genome	14 crisprs	WYL,csa3,DEDDh,cas3,DinG	6	9	8	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP026964_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_1

107694-107785

Orphan

Consensus_repeat	Method
CTTTAGCGATTAGAGGCTTTTATGCAGTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_1

>merge|CP026964|1|107694-107785|CRISPRCasFinder
CTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCGCAAGCAAGCCAACTGCGTTCCTCTTCACCTTTAGCGATTAGAGGCTTTTATGCAGTTG

>CP026964|1|1|107694-107785|CRISPRCasFinder
CTTTAGCGATTAGAGGCTTTTATGCAGTTG	TGCGCAAGCAAGCCAACTGCGTTCCTCTTCAC
CTTTAGCGATTAGAGGCTTTTATGCAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG65451.1\|104116_104917_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP026964.1\|AVG65447.1\|101015_101390_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
CP026964.1\|AVG65445.1\|98719_98944_+\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
CP026964.1\|AVG65454.1\|108937_110599_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP026964.1\|AVG65458.1\|114681_115158_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026964.1\|AVG65446.1\|99138_100068_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225778
CP026964.1\|AVG67987.1\|106773_107601_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
CP026964.1\|AVG65453.1\|107911_108547_-\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
CP026964.1\|AVG65449.1\|102596_103313_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67988.1\|110595_110979_-\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
CP026964.1\|AVG67989.1\|112797_113319_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
CP026964.1\|AVG65457.1\|113346_114642_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
CP026964.1\|AVG65460.1\|116073_117012_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
CP026964.1\|AVG65450.1\|103474_103981_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG65452.1\|104900_105620_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
CP026964.1\|AVG65459.1\|115326_115863_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
CP026964.1\|AVG65448.1\|101639_102428_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP026964.1\|AVG65456.1\|111288_112299_-\|zinc-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP026964.1\|AVG65455.1\|111104_111212_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67986.1\|105674_106625_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG65451.1\|104116_104917_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.45049e-26
CP026964.1\|AVG65447.1\|101015_101390_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP026964.1\|AVG65445.1\|98719_98944_+\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
CP026964.1\|AVG65454.1\|108937_110599_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP026964.1\|AVG65458.1\|114681_115158_-\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP026964.1\|AVG65446.1\|99138_100068_+\|hypothetical-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	6.05558e-37
CP026964.1\|AVG67987.1\|106773_107601_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.66421e-73
CP026964.1\|AVG65453.1\|107911_108547_-\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	6.89847e-90
CP026964.1\|AVG67988.1\|110595_110979_-\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.47258e-53
CP026964.1\|AVG67989.1\|112797_113319_-\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
CP026964.1\|AVG65460.1\|116073_117012_-\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
CP026964.1\|AVG65452.1\|104900_105620_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
CP026964.1\|AVG65459.1\|115326_115863_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP026964.1\|AVG65448.1\|101639_102428_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	9.91231e-35
CP026964.1\|AVG65456.1\|111288_112299_-\|zinc-dependent-alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP026964.1\|AVG65457.1\|113346_114642_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
CP026964.1\|AVG67986.1\|105674_106625_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	6.43614e-48

>CP026964.1|AVG67987.1|106773_107601_-|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKEGKKQFDALNLNKEELLKEKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP026964.1|AVG67986.1|105674_106625_-|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP026964.1|AVG65452.1|104900_105620_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>CP026964.1|AVG65451.1|104116_104917_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAQLAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV
>CP026964.1|AVG65450.1|103474_103981_-|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP026964.1|AVG65449.1|102596_103313_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>CP026964.1|AVG65448.1|101639_102428_-|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLNFLKSVS
>CP026964.1|AVG65447.1|101015_101390_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP026964.1|AVG65446.1|99138_100068_+|hypothetical-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSITLLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>CP026964.1|AVG65445.1|98719_98944_+|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>CP026964.1|AVG65453.1|107911_108547_-|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQVKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>CP026964.1|AVG65454.1|108937_110599_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKCEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP026964.1|AVG67988.1|110595_110979_-|DUF1934-domain-containing-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLDVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP026964.1|AVG65455.1|111104_111212_-|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>CP026964.1|AVG65456.1|111288_112299_-|zinc-dependent-alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP026964.1|AVG67989.1|112797_113319_-|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP026964.1|AVG65457.1|113346_114642_-|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP026964.1|AVG65458.1|114681_115158_-|N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP026964.1|AVG65459.1|115326_115863_-|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP026964.1|AVG65460.1|116073_117012_-|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED

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Crispr_ID: CP026964_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_2

806401-806574

Orphan

Consensus_repeat	Method
TGCAAGTTGG---CGGGGCCCCAACATAGAAGCTGGCGGAAAG	PILER-CR
TTACAATAATGTGCAAGTTGGCGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP026964_2

>merge|CP026964|2|806401-806574|PILER-CR,CRISPRCasFinder
TTGGCGAGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACAAAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGGTTACAATAATGTGCAAGTTGGGGT

>CP026964|2|1|806401-806545|PILER-CR
TTGGCGAGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCA	AGTTGGCGGGGCCCCAA
CAAAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCC	CAACATAGAAGCTGGC
GGAAAG

>CP026964|2|2|806495-806574|CRISPRCasFinder
TTACAATAATGTGCAAGTTGGCGG	GGCCCCAACATAGAAGCTGGCGGAAAGTCAGG
TTACAATAATGTGCAAGTTGGGGT

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG66059.1\|797685_798936_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|172308
CP026964.1\|AVG66061.1\|799933_800512_+\|imidazoleglycerol-phosphate-dehydratase	unknown	unknown	gnl\|CDD\|153419
CP026964.1\|AVG66065.1\|802535_803168_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl\|CDD\|235067
CP026964.1\|AVG66068.1\|806748_807801_-\|poly-beta-1,6-N-acetyl-D-glucosamine-export-protein	unknown	unknown	gnl\|CDD\|226446
CP026964.1\|AVG66077.1\|814609_815086_+\|peptide-methionine-(S)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|235497
CP026964.1\|AVG66062.1\|800508_801087_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|171871
CP026964.1\|AVG66060.1\|798951_799965_+\|histidinol-phosphate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223157
CP026964.1\|AVG66074.1\|812415_813108_+\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|349772
CP026964.1\|AVG66072.1\|810327_810888_+\|biofilm-operon-icaADBC-HTH-type-negative-transcriptional-regulator-IcaR	unknown	unknown	gnl\|CDD\|376089
CP026964.1\|AVG66067.1\|804260_806303_+\|Lipase-1	unknown	unknown	gnl\|CDD\|224001
CP026964.1\|AVG66076.1\|814106_814607_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
CP026964.1\|AVG66066.1\|803360_803540_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66075.1\|813104_813872_+\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226870
CP026964.1\|AVG66069.1\|807787_808660_-\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	unknown	unknown	gnl\|CDD\|188448
CP026964.1\|AVG66058.1\|797078_797693_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|172153
CP026964.1\|AVG66064.1\|801780_802539_+\|imidazole-glycerol-phosphate-synthase-cyclase-subunit	unknown	unknown	gnl\|CDD\|234996
CP026964.1\|AVG66071.1\|808925_810164_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|274866
CP026964.1\|AVG66063.1\|801079_801784_+\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|172156
CP026964.1\|AVG66070.1\|808656_808962_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthesis-protein-IcaD	unknown	unknown	gnl\|CDD\|188447
CP026964.1\|AVG66073.1\|811736_812399_+\|capsular-polysaccharide-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|226453

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG66059.1\|797685_798936_+\|histidinol-dehydrogenase	gnl\|CDD\|172308	PRK13770, PRK13770, histidinol dehydrogenase; Provisional.	0
CP026964.1\|AVG66061.1\|799933_800512_+\|imidazoleglycerol-phosphate-dehydratase	gnl\|CDD\|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	2.40504e-103
CP026964.1\|AVG66065.1\|802535_803168_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	1.51084e-110
CP026964.1\|AVG66068.1\|806748_807801_-\|poly-beta-1,6-N-acetyl-D-glucosamine-export-protein	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	5.4483e-115
CP026964.1\|AVG66077.1\|814609_815086_+\|peptide-methionine-(S)-S-oxide-reductase	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	1.4924e-106
CP026964.1\|AVG66062.1\|800508_801087_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	1.76981e-127
CP026964.1\|AVG66060.1\|798951_799965_+\|histidinol-phosphate-aminotransferase-family-protein	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	3.69083e-82
CP026964.1\|AVG66074.1\|812415_813108_+\|capsular-biosynthesis-protein	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.83977e-84
CP026964.1\|AVG66072.1\|810327_810888_+\|biofilm-operon-icaADBC-HTH-type-negative-transcriptional-regulator-IcaR	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	2.88245e-28
CP026964.1\|AVG66067.1\|804260_806303_+\|Lipase-1	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	1.58472e-82
CP026964.1\|AVG66076.1\|814106_814607_+\|N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.30563e-13
CP026964.1\|AVG66069.1\|807787_808660_-\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	1.47819e-150
CP026964.1\|AVG66075.1\|813104_813872_+\|capsular-biosynthesis-protein	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.38228e-144
CP026964.1\|AVG66058.1\|797078_797693_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|172153	PRK13584, hisG, ATP phosphoribosyltransferase.	2.32782e-134
CP026964.1\|AVG66064.1\|801780_802539_+\|imidazole-glycerol-phosphate-synthase-cyclase-subunit	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	5.46363e-153
CP026964.1\|AVG66071.1\|808925_810164_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0
CP026964.1\|AVG66063.1\|801079_801784_+\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	2.24553e-168
CP026964.1\|AVG66070.1\|808656_808962_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthesis-protein-IcaD	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.14464e-30
CP026964.1\|AVG66073.1\|811736_812399_+\|capsular-polysaccharide-biosynthesis-protein-CapA	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	5.65863e-89

>CP026964.1|AVG66067.1|804260_806303_+|Lipase-1
MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRIKEAPSLNKLDQTSQREIVNETEIEKVQPQQNNQANDKITNYNFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNHDNMISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTKATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKLTDTKQA
>CP026964.1|AVG66066.1|803360_803540_+|hypothetical-protein
MKSELSNSGIDVTVKDVEKYMNRYNEVMKGKNGEKAKELCLSLLPINIIVVFTFFVFIL
>CP026964.1|AVG66065.1|802535_803168_+|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase
MTNYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>CP026964.1|AVG66064.1|801780_802539_+|imidazole-glycerol-phosphate-synthase-cyclase-subunit
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTTGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>CP026964.1|AVG66063.1|801079_801784_+|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase
MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
>CP026964.1|AVG66062.1|800508_801087_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNTSKIIDQAETIILPGVGHFKDAMSEIKRLNLNAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGADIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
>CP026964.1|AVG66061.1|799933_800512_+|imidazoleglycerol-phosphate-dehydratase
MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
>CP026964.1|AVG66060.1|798951_799965_+|histidinol-phosphate-aminotransferase-family-protein
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLLPEQIIAGNGSDELIQKLMLIMPKGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGMAYDVEMAPHILRMRTLSKAFGIAGLRLGVLISTAGTIQRIQKIEHPYPLNVFTLNIATYIFRHREETRVFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYGEPVMKGYVRYSIATAPQLNQLEEIVKEWSAKYDLSKTTKHS
>CP026964.1|AVG66059.1|797685_798936_+|histidinol-dehydrogenase
MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYNLTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEESVECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSQEVLAACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGIDQIAGPTEIALIIDDTADLDAIVYDVFAQAEHDELARTYVIGEDAQVLKDLESRIAKALPNVDRYDIVSKSIANQHYLIHASNFDEACHVMNTIAPEHASIQTVNPQPYIEKVKYVGALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFEQIADSAQHIAHVEALYNHQQSILIRQS
>CP026964.1|AVG66058.1|797078_797693_+|ATP-phosphoribosyltransferase
MLRIAIAKGRLMDSLINYLDVIEYTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPETTNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
>CP026964.1|AVG66068.1|806748_807801_-|poly-beta-1,6-N-acetyl-D-glucosamine-export-protein
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
>CP026964.1|AVG66069.1|807787_808660_-|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>CP026964.1|AVG66070.1|808656_808962_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthesis-protein-IcaD
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
>CP026964.1|AVG66071.1|808925_810164_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESDTIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>CP026964.1|AVG66072.1|810327_810888_+|biofilm-operon-icaADBC-HTH-type-negative-transcriptional-regulator-IcaR
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
>CP026964.1|AVG66073.1|811736_812399_+|capsular-polysaccharide-biosynthesis-protein-CapA
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
>CP026964.1|AVG66074.1|812415_813108_+|capsular-biosynthesis-protein
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>CP026964.1|AVG66075.1|813104_813872_+|capsular-biosynthesis-protein
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILKGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>CP026964.1|AVG66076.1|814106_814607_+|N-acetyltransferase
MVLRKVIMQDLDQIIALENIGFSPEEAATREALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVSTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFETLAKNHHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV
>CP026964.1|AVG66077.1|814609_815086_+|peptide-methionine-(S)-S-oxide-reductase
MAVVYVAGGCLWGVEAFFATIPGIIHTEAGRANGRSSKLDGPYDGYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNQQGNDIGQKYRTGLYSCVDDHLIEARQFIERRKDRDQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISKDLLNKYK

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Crispr_ID: CP026964_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_3

938832-938939

Orphan

Consensus_repeat	Method
CCAACTGTAAACCGTAGTGTACTTATTATTTATAATAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_3

>merge|CP026964|3|938832-938939|CRISPRCasFinder
CCAACTGTAAACCGTAGTGTACTTATTATTTATAATAATTAGTGGCTCTTATGCAGTTGGAGCGAAGATCCAACTGTAAACCGTAGTGTACTTATTATTTATAATAAT

>CP026964|3|3|938832-938939|CRISPRCasFinder
CCAACTGTAAACCGTAGTGTACTTATTATTTATAATAAT	TAGTGGCTCTTATGCAGTTGGAGCGAAGAT
CCAACTGTAAACCGTAGTGTACTTATTATTTATAATAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG66181.1\|937464_938463_+\|lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|181499
CP026964.1\|AVG66191.1\|950517_950688_+\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
CP026964.1\|AVG66185.1\|942185_942785_+\|maltose-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
CP026964.1\|AVG68022.1\|930333_930822_+\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
CP026964.1\|AVG66174.1\|927219_929031_+\|O-acetyltransferase-OatA	unknown	unknown	gnl\|CDD\|224748
CP026964.1\|AVG68023.1\|945587_948056_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
CP026964.1\|AVG66184.1\|941755_941947_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66179.1\|934352_935861_+\|dehydrosqualene-desaturase	unknown	unknown	gnl\|CDD\|224154
CP026964.1\|AVG66186.1\|942974_944519_+\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
CP026964.1\|AVG66175.1\|929391_930159_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
CP026964.1\|AVG66178.1\|933477_934341_+\|dehydrosqualene-synthase	unknown	unknown	gnl\|CDD\|224478
CP026964.1\|AVG66188.1\|944873_945422_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP026964.1\|AVG66182.1\|938552_938759_-\|copper-resistance-protein-CopZ	unknown	unknown	gnl\|CDD\|225328
CP026964.1\|AVG66189.1\|948271_948499_+\|ferrous-iron-transporter-A	unknown	unknown	gnl\|CDD\|224830
CP026964.1\|AVG66187.1\|944630_944798_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66190.1\|948510_950505_+\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
CP026964.1\|AVG66180.1\|936287_937442_+\|N-succinyldiaminopimelate-aminotransferase	unknown	unknown	gnl\|CDD\|181219
CP026964.1\|AVG66177.1\|932313_933441_+\|4,4'-diaponeurosporenoate-glycosyltransferase	unknown	unknown	gnl\|CDD\|132997
CP026964.1\|AVG66183.1\|939107_941516_-\|copper-exporting-P-type-ATPase-A	unknown	unknown	gnl\|CDD\|319783
CP026964.1\|AVG66176.1\|930814_932308_+\|diapolycopene-oxygenase	unknown	unknown	gnl\|CDD\|224154

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG66181.1\|937464_938463_+\|lactate-dehydrogenase	gnl\|CDD\|181499	PRK08605, PRK08605, D-lactate dehydrogenase; Validated.	0
CP026964.1\|AVG66191.1\|950517_950688_+\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00119197
CP026964.1\|AVG66185.1\|942185_942785_+\|maltose-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.94515e-91
CP026964.1\|AVG66176.1\|930814_932308_+\|diapolycopene-oxygenase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	9.69418e-133
CP026964.1\|AVG66174.1\|927219_929031_+\|O-acetyltransferase-OatA	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84
CP026964.1\|AVG68023.1\|945587_948056_+\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	4.1848e-169
CP026964.1\|AVG66179.1\|934352_935861_+\|dehydrosqualene-desaturase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.03717e-133
CP026964.1\|AVG66186.1\|942974_944519_+\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
CP026964.1\|AVG66175.1\|929391_930159_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.53845e-31
CP026964.1\|AVG66178.1\|933477_934341_+\|dehydrosqualene-synthase	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.37403e-100
CP026964.1\|AVG66188.1\|944873_945422_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.81924e-09
CP026964.1\|AVG66182.1\|938552_938759_-\|copper-resistance-protein-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	3.85103e-21
CP026964.1\|AVG66189.1\|948271_948499_+\|ferrous-iron-transporter-A	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	9.02667e-20
CP026964.1\|AVG66190.1\|948510_950505_+\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
CP026964.1\|AVG66180.1\|936287_937442_+\|N-succinyldiaminopimelate-aminotransferase	gnl\|CDD\|181219	PRK08068, PRK08068, transaminase; Reviewed.	2.7078e-143
CP026964.1\|AVG66177.1\|932313_933441_+\|4,4'-diaponeurosporenoate-glycosyltransferase	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	9.85714e-23
CP026964.1\|AVG66183.1\|939107_941516_-\|copper-exporting-P-type-ATPase-A	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>CP026964.1|AVG66182.1|938552_938759_-|copper-resistance-protein-CopZ
MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
>CP026964.1|AVG66181.1|937464_938463_+|lactate-dehydrogenase
MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVAGYDGLSLSQQIPLSEHVYKRLNELDIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYSPNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRVVADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLFNAELFKHFKKGAVFVNCARGSLVDTKALLDALDNGVIKGAALDTYEFERKLFPSDQRGKTLNDPLLESLIDREDVILTPHIAFYTEAAVKNLIVDALDATLDVLQTGDTRLRVN
>CP026964.1|AVG66180.1|936287_937442_+|N-succinyldiaminopimelate-aminotransferase
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQQALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSTVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE
>CP026964.1|AVG66179.1|934352_935861_+|dehydrosqualene-desaturase
MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIEQGV
>CP026964.1|AVG66178.1|933477_934341_+|dehydrosqualene-synthase
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
>CP026964.1|AVG66177.1|932313_933441_+|4,4'-diaponeurosporenoate-glycosyltransferase
MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
>CP026964.1|AVG66176.1|930814_932308_+|diapolycopene-oxygenase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGIPMVTLSGQQVADKINAREAKNRK
>CP026964.1|AVG68022.1|930333_930822_+|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>CP026964.1|AVG66175.1|929391_930159_+|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>CP026964.1|AVG66174.1|927219_929031_+|O-acetyltransferase-OatA
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>CP026964.1|AVG66183.1|939107_941516_-|copper-exporting-P-type-ATPase-A
MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTYYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
>CP026964.1|AVG66184.1|941755_941947_-|hypothetical-protein
MRILITGTVAILIILGLVKTIQDHEMTNDTSRQLSDNKDDDKVIHLNNFKNLHAKEFNPSDFF
>CP026964.1|AVG66185.1|942185_942785_+|maltose-acetyltransferase
MTEKEKMLAEKWYDANFDQYLINERARAKDICFELNHTRPSATNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
>CP026964.1|AVG66186.1|942974_944519_+|L-glutamate-gamma-semialdehyde-dehydrogenase
MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNIVLLKPAEDTPYIAYKLMGILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
>CP026964.1|AVG66187.1|944630_944798_+|hypothetical-protein
MRYVISIIMGIVLAIWSFKQLSQSHLDSGFIFFFIVYVLCISYFNSDKHDKNKKR
>CP026964.1|AVG66188.1|944873_945422_-|TetR/AcrR-family-transcriptional-regulator
MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHRTTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLRDIAEFQEEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSDIPDNLIFYIYDSLIEGFMHWIKDEKIDWPGEEIDKIFHKVINIKIK
>CP026964.1|AVG68023.1|945587_948056_+|MMPL-family-transporter
MGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDNDIKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITKDIKKTLDDIKKDDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNVQTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGIISLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYIKGIGLAIGTAGSAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVFSALTLLPALISIFHKRIKVNKLQSNFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPADSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDIVTPPQMSKDNDYALMVVIPKKGPNAESTNDLVHDLRDYHKDAQDKYGFKTEISGQSVINIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLVMQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYSIKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIPALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKIYPQGATNVSKHQDVHGQDDVRSIVLDDKTMALYQEVKQQSASSFFLYDALIDYQNKHQLNSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS
>CP026964.1|AVG66189.1|948271_948499_+|ferrous-iron-transporter-A
MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQKCLFKGPCIIEVNGQQLSIRHCDACSIALEE
>CP026964.1|AVG66190.1|948510_950505_+|ferrous-iron-transporter-B
MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKHLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVDKQVEAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVVYPLVTAYVLTFIFYQIGHLFV
>CP026964.1|AVG66191.1|950517_950688_+|FeoB-associated-Cys-rich-membrane-protein
MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDINRDCCGTEQHTANHFPGK

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Crispr_ID: CP026964_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_4

1079074-1079152

Orphan

Consensus_repeat	Method
TTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_4

>merge|CP026964|4|1079074-1079152|CRISPRCasFinder
TTTCTACAGACAATGCAAGTTGGCGGAGTCCCAACTAAGAGAAATTGGATTCCCAATTTCTAGAGACAATGCAAGTTGG

>CP026964|4|4|1079074-1079152|CRISPRCasFinder
TTTCTACAGACAATGCAAGTTGG	CGGAGTCCCAACTAAGAGAAATTGGATTCCCAA
TTTCTAGAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG66305.1\|1072393_1073200_+\|phosphohydrolase	unknown	unknown	gnl\|CDD\|163441
CP026964.1\|AVG66322.1\|1087559_1088252_+\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
CP026964.1\|AVG66315.1\|1081238_1082972_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP026964.1\|AVG66312.1\|1078659_1078767_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66317.1\|1083202_1083370_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66313.1\|1078793_1078901_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66314.1\|1079450_1081214_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
CP026964.1\|AVG66306.1\|1073262_1073919_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227323
CP026964.1\|AVG66320.1\|1085448_1086456_+\|biotin-synthase	unknown	unknown	gnl\|CDD\|235755
CP026964.1\|AVG66311.1\|1078139_1078526_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|225155
CP026964.1\|AVG66323.1\|1088262_1088730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
CP026964.1\|AVG66308.1\|1074627_1075839_-\|Bcr/CflA-family-drug-resistance-efflux-transporter	unknown	unknown	gnl\|CDD\|340878
CP026964.1\|AVG66316.1\|1083059_1083203_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66307.1\|1074031_1074505_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
CP026964.1\|AVG66309.1\|1076020_1076680_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222878
CP026964.1\|AVG66321.1\|1086433_1087549_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|223234
CP026964.1\|AVG66319.1\|1084088_1085447_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
CP026964.1\|AVG66310.1\|1076739_1077882_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872
CP026964.1\|AVG66304.1\|1070698_1072108_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
CP026964.1\|AVG66318.1\|1083424_1084111_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG66305.1\|1072393_1073200_+\|phosphohydrolase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	1.39132e-107
CP026964.1\|AVG66322.1\|1087559_1088252_+\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.89049e-130
CP026964.1\|AVG66315.1\|1081238_1082972_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.79158e-143
CP026964.1\|AVG66314.1\|1079450_1081214_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.21336e-146
CP026964.1\|AVG66306.1\|1073262_1073919_-\|hypothetical-protein	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
CP026964.1\|AVG66320.1\|1085448_1086456_+\|biotin-synthase	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
CP026964.1\|AVG66323.1\|1088262_1088730_+\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179995
CP026964.1\|AVG66311.1\|1078139_1078526_+\|GtrA-family-protein	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.41026e-22
CP026964.1\|AVG66308.1\|1074627_1075839_-\|Bcr/CflA-family-drug-resistance-efflux-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
CP026964.1\|AVG66307.1\|1074031_1074505_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	2.01209e-37
CP026964.1\|AVG66309.1\|1076020_1076680_-\|hypothetical-protein	gnl\|CDD\|222878	PHA02562, 46, endonuclease subunit; Provisional.	0.00700231
CP026964.1\|AVG66321.1\|1086433_1087549_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	3.62949e-138
CP026964.1\|AVG66319.1\|1084088_1085447_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
CP026964.1\|AVG66310.1\|1076739_1077882_-\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
CP026964.1\|AVG66304.1\|1070698_1072108_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
CP026964.1\|AVG66318.1\|1083424_1084111_+\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70

>CP026964.1|AVG66313.1|1078793_1078901_+|hypothetical-protein
MAVVRGFGVFRCSIYYVINYSIDEQGVQCIFVILQ
>CP026964.1|AVG66312.1|1078659_1078767_+|hypothetical-protein
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
>CP026964.1|AVG66311.1|1078139_1078526_+|GtrA-family-protein
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>CP026964.1|AVG66310.1|1076739_1077882_-|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVQFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>CP026964.1|AVG66309.1|1076020_1076680_-|hypothetical-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDENGGAN
>CP026964.1|AVG66308.1|1074627_1075839_-|Bcr/CflA-family-drug-resistance-efflux-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>CP026964.1|AVG66307.1|1074031_1074505_+|AraC-family-transcriptional-regulator
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCISELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>CP026964.1|AVG66306.1|1073262_1073919_-|hypothetical-protein
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>CP026964.1|AVG66305.1|1072393_1073200_+|phosphohydrolase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>CP026964.1|AVG66304.1|1070698_1072108_-|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSMLVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>CP026964.1|AVG66314.1|1079450_1081214_+|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
>CP026964.1|AVG66315.1|1081238_1082972_+|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>CP026964.1|AVG66316.1|1083059_1083203_+|hypothetical-protein
MRGFGVFRCSIYYVTNYSIDEQGAQRNITINGLFHKMVKLGCLFVKK
>CP026964.1|AVG66317.1|1083202_1083370_+|hypothetical-protein
MQLLILTDIFYRIAVYICPNSLRSLSHFNSKVKILPKFIVILRSLNSCFLEKHAP
>CP026964.1|AVG66318.1|1083424_1084111_+|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>CP026964.1|AVG66319.1|1084088_1085447_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEETIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>CP026964.1|AVG66320.1|1085448_1086456_+|biotin-synthase
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>CP026964.1|AVG66321.1|1086433_1087549_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSAFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>CP026964.1|AVG66322.1|1087559_1088252_+|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYERV
>CP026964.1|AVG66323.1|1088262_1088730_+|hypothetical-protein
MTSKDITQISVIAAILTILAALKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLVFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR

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Crispr_ID: CP026964_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_5

1246017-1246102

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_5

>merge|CP026964|5|1246017-1246102|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGGTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGG

>CP026964|5|5|1246017-1246102|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGGTGACGA
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG66485.1\|1248674_1249439_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
CP026964.1\|AVG66476.1\|1243006_1243492_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
CP026964.1\|AVG66473.1\|1240685_1241192_+\|molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223595
CP026964.1\|AVG66482.1\|1246416_1246767_+\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP026964.1\|AVG66475.1\|1241750_1243010_+\|molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452
CP026964.1\|AVG66474.1\|1241193_1241688_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
CP026964.1\|AVG66488.1\|1251452_1254620_+\|AcrB/AcrD/AcrF-family-protein	unknown	unknown	gnl\|CDD\|223911
CP026964.1\|AVG66471.1\|1238875_1239481_+\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226628
CP026964.1\|AVG66487.1\|1250070_1251336_+\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
CP026964.1\|AVG66481.1\|1246120_1246291_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66486.1\|1249430_1249682_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66489.1\|1254803_1255121_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66477.1\|1243505_1243952_+\|molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP026964.1\|AVG66484.1\|1248072_1248513_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP026964.1\|AVG66479.1\|1244197_1244797_+\|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP026964.1\|AVG66483.1\|1246868_1248080_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
CP026964.1\|AVG66480.1\|1244816_1245839_+\|cyclic-pyranopterin-monophosphate-synthase	unknown	unknown	gnl\|CDD\|274250
CP026964.1\|AVG66478.1\|1243957_1244191_+\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|340452
CP026964.1\|AVG66490.1\|1255365_1255530_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66472.1\|1239650_1240655_+\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG66485.1\|1248674_1249439_+\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.64519e-37
CP026964.1\|AVG66476.1\|1243006_1243492_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
CP026964.1\|AVG66473.1\|1240685_1241192_+\|molybdenum-cofactor-biosynthesis-protein	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
CP026964.1\|AVG66475.1\|1241750_1243010_+\|molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.35078e-159
CP026964.1\|AVG66474.1\|1241193_1241688_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	9.25584e-98
CP026964.1\|AVG66488.1\|1251452_1254620_+\|AcrB/AcrD/AcrF-family-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP026964.1\|AVG66487.1\|1250070_1251336_+\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	3.69463e-143
CP026964.1\|AVG66471.1\|1238875_1239481_+\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
CP026964.1\|AVG66477.1\|1243505_1243952_+\|molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP026964.1\|AVG66484.1\|1248072_1248513_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.28933e-15
CP026964.1\|AVG66479.1\|1244197_1244797_+\|molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP026964.1\|AVG66483.1\|1246868_1248080_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.54033e-72
CP026964.1\|AVG66480.1\|1244816_1245839_+\|cyclic-pyranopterin-monophosphate-synthase	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP026964.1\|AVG66482.1\|1246416_1246767_+\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP026964.1\|AVG66478.1\|1243957_1244191_+\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
CP026964.1\|AVG66472.1\|1239650_1240655_+\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.72461e-131

>CP026964.1|AVG66480.1|1244816_1245839_+|cyclic-pyranopterin-monophosphate-synthase
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP026964.1|AVG66479.1|1244197_1244797_+|molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP026964.1|AVG66478.1|1243957_1244191_+|molybdopterin-synthase-sulfur-carrier-subunit
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP026964.1|AVG66477.1|1243505_1243952_+|molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP026964.1|AVG66476.1|1243006_1243492_+|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP026964.1|AVG66475.1|1241750_1243010_+|molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP026964.1|AVG66474.1|1241193_1241688_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNKTIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>CP026964.1|AVG66473.1|1240685_1241192_+|molybdenum-cofactor-biosynthesis-protein
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP026964.1|AVG66472.1|1239650_1240655_+|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLIDDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWDGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP026964.1|AVG66471.1|1238875_1239481_+|molybdenum-ABC-transporter-ATP-binding-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
>CP026964.1|AVG66481.1|1246120_1246291_-|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>CP026964.1|AVG66482.1|1246416_1246767_+|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP026964.1|AVG66483.1|1246868_1248080_-|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYPIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP026964.1|AVG66484.1|1248072_1248513_-|MarR-family-transcriptional-regulator
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHKILLKETHND
>CP026964.1|AVG66485.1|1248674_1249439_+|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNNIEAVKNKLQSERVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP026964.1|AVG66486.1|1249430_1249682_-|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>CP026964.1|AVG66487.1|1250070_1251336_+|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP026964.1|AVG66488.1|1251452_1254620_+|AcrB/AcrD/AcrF-family-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTFAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVVTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGNIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP026964.1|AVG66489.1|1254803_1255121_-|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTMMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP026964.1|AVG66490.1|1255365_1255530_-|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD

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Crispr_ID: CP026964_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_6

1357528-1357609

Orphan

Consensus_repeat	Method
AAGAAGCCCCTAACAACTAAAGTTG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP026964_6

>merge|CP026964|6|1357528-1357609|CRISPRCasFinder
AAGAAGCCCCTAACAACTAAAGTTGAAAAGTAGGAGCGCCTGCGCTAAGCGCATGCATAAGAGCCCCTAACAACTAAAGTTG

>CP026964|6|6|1357528-1357609|CRISPRCasFinder
AAGAAGCCCCTAACAACTAAAGTTG	AAAAGTAGGAGCGCCTGCGCTAAGCGCATGCA
TAAGAGCCCCTAACAACTAAAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG66596.1\|1359964_1360285_-\|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP026964.1\|AVG66595.1\|1358982_1359963_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
CP026964.1\|AVG66601.1\|1365239_1365653_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
CP026964.1\|AVG66600.1\|1363408_1364782_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP026964.1\|AVG66589.1\|1354734_1355592_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP026964.1\|AVG66597.1\|1360436_1361102_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
CP026964.1\|AVG66593.1\|1357088_1357193_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66590.1\|1355721_1355814_-\|erm-Leader-peptide	unknown	unknown	unknown
CP026964.1\|AVG66602.1\|1365852_1366296_+\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP026964.1\|AVG66598.1\|1361537_1362476_+\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP026964.1\|AVG66594.1\|1357625_1358717_-\|transcriptional-regulator	unknown	unknown	unknown
CP026964.1\|AVG66599.1\|1362506_1362737_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66591.1\|1356250_1356409_-\|integrase	unknown	unknown	unknown
CP026964.1\|AVG66584.1\|1347015_1347450_-\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP026964.1\|AVG66586.1\|1349628_1351167_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
CP026964.1\|AVG66585.1\|1347461_1349594_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
CP026964.1\|AVG66603.1\|1366416_1367127_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP026964.1\|AVG66587.1\|1351847_1353653_+\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP026964.1\|AVG66592.1\|1356473_1356656_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG66588.1\|1353884_1354667_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG66596.1\|1359964_1360285_-\|ArsR-family-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP026964.1\|AVG66595.1\|1358982_1359963_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
CP026964.1\|AVG66601.1\|1365239_1365653_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.46591e-45
CP026964.1\|AVG66603.1\|1366416_1367127_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
CP026964.1\|AVG66600.1\|1363408_1364782_+\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
CP026964.1\|AVG66598.1\|1361537_1362476_+\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
CP026964.1\|AVG66602.1\|1365852_1366296_+\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP026964.1\|AVG66584.1\|1347015_1347450_-\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP026964.1\|AVG66586.1\|1349628_1351167_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP026964.1\|AVG66585.1\|1347461_1349594_-\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
CP026964.1\|AVG66588.1\|1353884_1354667_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
CP026964.1\|AVG66587.1\|1351847_1353653_+\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP026964.1\|AVG66589.1\|1354734_1355592_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
CP026964.1\|AVG66597.1\|1360436_1361102_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47

>CP026964.1|AVG66593.1|1357088_1357193_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>CP026964.1|AVG66592.1|1356473_1356656_+|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>CP026964.1|AVG66591.1|1356250_1356409_-|integrase
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP026964.1|AVG66590.1|1355721_1355814_-|erm-Leader-peptide
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>CP026964.1|AVG66589.1|1354734_1355592_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP026964.1|AVG66588.1|1353884_1354667_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP026964.1|AVG66587.1|1351847_1353653_+|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP026964.1|AVG66586.1|1349628_1351167_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP026964.1|AVG66585.1|1347461_1349594_-|PRD-domain-containing-protein
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP026964.1|AVG66584.1|1347015_1347450_-|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>CP026964.1|AVG66594.1|1357625_1358717_-|transcriptional-regulator
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP026964.1|AVG66595.1|1358982_1359963_-|cation-transporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>CP026964.1|AVG66596.1|1359964_1360285_-|ArsR-family-transcriptional-regulator
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP026964.1|AVG66597.1|1360436_1361102_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>CP026964.1|AVG66598.1|1361537_1362476_+|mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP026964.1|AVG66599.1|1362506_1362737_+|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP026964.1|AVG66600.1|1363408_1364782_+|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP026964.1|AVG66601.1|1365239_1365653_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDCIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP026964.1|AVG66602.1|1365852_1366296_+|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP026964.1|AVG66603.1|1366416_1367127_-|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE

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Crispr_ID: CP026964_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_8

1884559-1884711

Orphan

Consensus_repeat	Method
AAGTTGGGGACGGGGCCCCAACACAGA	CRISPRCasFinder
TGCAAGTTGGGGACGGGGCCCCAACACAGA--------GAAATTCG	PILER-CR

2 spacers

The CRISPR arrays of CP026964_8

>merge|CP026964|8|1884559-1884711|CRISPRCasFinder,PILER-CR
GTTATATTGGCGGGGCCCCAACACAGAGAAATTGGGACCCCAATTTCAACAGGCAATGGAAGTTGGGGACGGGGCCCCAACACAGAAGCTGACCAAAAGTCAGATTTCAATAATGTGCAAGTTGGGGATGGGGCCCCAACACAGAGAATTTCG

>CP026964|8|8|1884559-1884703|CRISPRCasFinder
GTTATATTGGCGGGGCCCCAACACAGA	GAAATTGGGACCCCAATTTCAACAGGCAATGG
AAGTTGGGGACGGGGCCCCAACACAGA	AGCTGACCAAAAGTCAGATTTCAATAATGTGC
AAGTTGGGGATGGGGCCCCAACACAGA

>CP026964|8|2|1884569-1884711|PILER-CR
CGGGGCCCCAACACAGAGAAATTGGGACCCCAATTTCA	ACAGGCAATGGAAGTTGGGGA
CGGGGCCCCAACACAGAAGCTGACCAAAAGTCAGATTT	CAATAATGTGCAAGTTGGGGATGGGGCCC
CAACACAGAGAATTTCG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67103.1\|1885015_1885684_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
CP026964.1\|AVG67097.1\|1879721_1880144_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
CP026964.1\|AVG67105.1\|1888505_1891136_+\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
CP026964.1\|AVG67096.1\|1878362_1879637_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
CP026964.1\|AVG67110.1\|1893139_1894063_+\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
CP026964.1\|AVG67099.1\|1880465_1880612_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67108.1\|1891905_1892214_+\|DUF1292-domain-containing-protein	unknown	unknown	gnl\|CDD\|184235
CP026964.1\|AVG67104.1\|1885685_1888163_+\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
CP026964.1\|AVG67095.1\|1877428_1878202_+\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
CP026964.1\|AVG67109.1\|1892498_1893137_+\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
CP026964.1\|AVG67111.1\|1894074_1895343_+\|collagenase-like-protease	unknown	unknown	gnl\|CDD\|223896
CP026964.1\|AVG67094.1\|1877300_1877429_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67107.1\|1891462_1891891_+\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|223886
CP026964.1\|AVG67112.1\|1895342_1895966_+\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
CP026964.1\|AVG67098.1\|1880243_1880426_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP026964.1\|AVG67106.1\|1891198_1891459_+\|IreB-family-regulatory-phosphoprotein	unknown	unknown	gnl\|CDD\|180108
CP026964.1\|AVG67101.1\|1882173_1883316_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
CP026964.1\|AVG67102.1\|1883316_1884435_+\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
CP026964.1\|AVG67100.1\|1880848_1881862_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
CP026964.1\|AVG67093.1\|1875201_1876968_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67103.1\|1885015_1885684_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.22121e-16
CP026964.1\|AVG67097.1\|1879721_1880144_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.58388e-46
CP026964.1\|AVG67105.1\|1888505_1891136_+\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
CP026964.1\|AVG67096.1\|1878362_1879637_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
CP026964.1\|AVG67110.1\|1893139_1894063_+\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87045e-104
CP026964.1\|AVG67106.1\|1891198_1891459_+\|IreB-family-regulatory-phosphoprotein	gnl\|CDD\|180108	PRK05473, IreB-like, IreB family regulatory phosphoprotein. IreB (EF1202) was characterized in Enterococcus faecalis as a small protein, well-conserved in the Firmicutes. It belongs to a system that includes the Ser/Thr protein kinase IreK, and phosphatase IreP, undergoes phosphorylation on threonine residues, and is involved in regulating cephalosporin resistance. This family was previously named DUF965 by Pfam model pfam06135.	3.05024e-47
CP026964.1\|AVG67108.1\|1891905_1892214_+\|DUF1292-domain-containing-protein	gnl\|CDD\|184235	PRK13678, PRK13678, hypothetical protein; Provisional.	1.28539e-26
CP026964.1\|AVG67104.1\|1885685_1888163_+\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
CP026964.1\|AVG67095.1\|1877428_1878202_+\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.59061e-126
CP026964.1\|AVG67109.1\|1892498_1893137_+\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	1.23148e-73
CP026964.1\|AVG67111.1\|1894074_1895343_+\|collagenase-like-protease	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	5.98972e-149
CP026964.1\|AVG67107.1\|1891462_1891891_+\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|223886	COG0816, COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair].	3.40149e-56
CP026964.1\|AVG67112.1\|1895342_1895966_+\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	5.13835e-138
CP026964.1\|AVG67098.1\|1880243_1880426_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.22501e-07
CP026964.1\|AVG67101.1\|1882173_1883316_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
CP026964.1\|AVG67102.1\|1883316_1884435_+\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP026964.1\|AVG67100.1\|1880848_1881862_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.49102e-173
CP026964.1\|AVG67093.1\|1875201_1876968_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0

>CP026964.1|AVG67102.1|1883316_1884435_+|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
>CP026964.1|AVG67101.1|1882173_1883316_+|cysteine-desulfurase
MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARKYLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSVLHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYDIQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVTLDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQERAIPFELNGSMTDATGHIVNLYFPFVEVETMLTLLDMAQIYVSSGSACTAGSTQPSHVLDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES
>CP026964.1|AVG67100.1|1880848_1881862_-|LLM-class-flavin-dependent-oxidoreductase
MAIKYSALNLVPIREGEDERTAINDMVKLAQHLDELSYERYWIAEHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNRVDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGKNVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVIVCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHELQNILTPREYAMAMERQKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEKNTL
>CP026964.1|AVG67099.1|1880465_1880612_+|hypothetical-protein
MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENEDKEK
>CP026964.1|AVG67098.1|1880243_1880426_+|CsbD-family-protein
MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
>CP026964.1|AVG67097.1|1879721_1880144_+|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>CP026964.1|AVG67096.1|1878362_1879637_-|replication-associated-recombination-protein-A
MSTEPLASRMRPKNIDEIISQQHLVGPRGIIRRMVDTKKLTSMIFYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQALTRAIEDEENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHVTLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSAMSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPDKLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP
>CP026964.1|AVG67095.1|1877428_1878202_+|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYTEETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTISDISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ
>CP026964.1|AVG67094.1|1877300_1877429_+|hypothetical-protein
MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK
>CP026964.1|AVG67093.1|1875201_1876968_+|aspartate--tRNA-ligase
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
>CP026964.1|AVG67103.1|1885015_1885684_+|tetratricopeptide-repeat-protein
MIDQQTIYQYIQNGKIEEALQALFGNIEENPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
>CP026964.1|AVG67104.1|1885685_1888163_+|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIMIRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVLTEATMFKIDPMINMGEITPYDFIER
>CP026964.1|AVG67105.1|1888505_1891136_+|alanine--tRNA-ligase
MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIENQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
>CP026964.1|AVG67106.1|1891198_1891459_+|IreB-family-regulatory-phosphoprotein
MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
>CP026964.1|AVG67107.1|1891462_1891891_+|Holliday-junction-resolvase-RuvX
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
>CP026964.1|AVG67108.1|1891905_1892214_+|DUF1292-domain-containing-protein
MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
>CP026964.1|AVG67109.1|1892498_1893137_+|O-methyltransferase
MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
>CP026964.1|AVG67110.1|1893139_1894063_+|U32-family-peptidase
MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQMTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVKAQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQVQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTHIMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYEDEKFMLMDPIEEIQPDHRPFDEGFLYKQTVY
>CP026964.1|AVG67111.1|1894074_1895343_+|collagenase-like-protease
MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG
>CP026964.1|AVG67112.1|1895342_1895966_+|uridine-kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ

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Crispr_ID: CP026964_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_9

2307826-2307911

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_9

>merge|CP026964|9|2307826-2307911|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>CP026964|9|9|2307826-2307911|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67480.1\|2294993_2297069_-\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
CP026964.1\|AVG67496.1\|2317486_2318218_-\|ribonuclease-3	unknown	unknown	gnl\|CDD\|234633
CP026964.1\|AVG67495.1\|2313773_2317340_-\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
CP026964.1\|AVG67479.1\|2293530_2294838_-\|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO	unknown	unknown	gnl\|CDD\|235416
CP026964.1\|AVG67492.1\|2310811_2312179_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
CP026964.1\|AVG67484.1\|2301834_2303001_-\|succinyl-CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
CP026964.1\|AVG67490.1\|2309410_2309914_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
CP026964.1\|AVG67487.1\|2305145_2307752_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226888
CP026964.1\|AVG67488.1\|2308220_2308571_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
CP026964.1\|AVG67494.1\|2312523_2313774_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
CP026964.1\|AVG67482.1\|2299559_2300678_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366664
CP026964.1\|AVG67486.1\|2303860_2304745_-\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
CP026964.1\|AVG67493.1\|2312204_2312537_-\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
CP026964.1\|AVG67483.1\|2300904_2301813_-\|succinyl-CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
CP026964.1\|AVG67485.1\|2303109_2303877_-\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003
CP026964.1\|AVG67491.1\|2310101_2310377_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
CP026964.1\|AVG67497.1\|2318333_2318567_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
CP026964.1\|AVG67489.1\|2308673_2309411_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
CP026964.1\|AVG67481.1\|2298287_2299532_-\|FemA/FemB-family-glycyltransferase-FmhC	unknown	unknown	gnl\|CDD\|367067
CP026964.1\|AVG68069.1\|2297242_2297983_-\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67480.1\|2294993_2297069_-\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
CP026964.1\|AVG67496.1\|2317486_2318218_-\|ribonuclease-3	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
CP026964.1\|AVG67495.1\|2313773_2317340_-\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
CP026964.1\|AVG67479.1\|2293530_2294838_-\|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
CP026964.1\|AVG67492.1\|2310811_2312179_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
CP026964.1\|AVG67484.1\|2301834_2303001_-\|succinyl-CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
CP026964.1\|AVG67490.1\|2309410_2309914_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
CP026964.1\|AVG67487.1\|2305145_2307752_+\|hypothetical-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
CP026964.1\|AVG67488.1\|2308220_2308571_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
CP026964.1\|AVG67494.1\|2312523_2313774_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
CP026964.1\|AVG67482.1\|2299559_2300678_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|366664	pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.	1.45655e-14
CP026964.1\|AVG67486.1\|2303860_2304745_-\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	2.28339e-159
CP026964.1\|AVG67493.1\|2312204_2312537_-\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
CP026964.1\|AVG67483.1\|2300904_2301813_-\|succinyl-CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
CP026964.1\|AVG67485.1\|2303109_2303877_-\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	9.05801e-95
CP026964.1\|AVG67491.1\|2310101_2310377_-\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
CP026964.1\|AVG67497.1\|2318333_2318567_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
CP026964.1\|AVG67489.1\|2308673_2309411_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.98496e-164
CP026964.1\|AVG67481.1\|2298287_2299532_-\|FemA/FemB-family-glycyltransferase-FmhC	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
CP026964.1\|AVG68069.1\|2297242_2297983_-\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	3.63797e-97

>CP026964.1|AVG67487.1|2305145_2307752_+|hypothetical-protein
MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSGAGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGSLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKLICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWLLFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKIKSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNKTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYAPPYYYLLITITIFGIICSIIFTRWARQK
>CP026964.1|AVG67486.1|2303860_2304745_-|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQHDLARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>CP026964.1|AVG67485.1|2303109_2303877_-|ribonuclease-HII
MTLTIKEVKQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
>CP026964.1|AVG67484.1|2301834_2303001_-|succinyl-CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>CP026964.1|AVG67483.1|2300904_2301813_-|succinyl-CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYEALLTVNK
>CP026964.1|AVG67482.1|2299559_2300678_-|LysM-peptidoglycan-binding-domain-containing-protein
MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQDIKISNTPKNSSQGNNLVINNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKPKTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
>CP026964.1|AVG67481.1|2298287_2299532_-|FemA/FemB-family-glycyltransferase-FmhC
MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIFEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV
>CP026964.1|AVG68069.1|2297242_2297983_-|DNA-protecting-protein-DprA
MNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
>CP026964.1|AVG67480.1|2294993_2297069_-|type-I-DNA-topoisomerase
MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
>CP026964.1|AVG67479.1|2293530_2294838_-|FADH(2)-oxidizing-methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))--methyltransferase-TrmFO
MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
>CP026964.1|AVG67488.1|2308220_2308571_-|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>CP026964.1|AVG67489.1|2308673_2309411_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>CP026964.1|AVG67490.1|2309410_2309914_-|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>CP026964.1|AVG67491.1|2310101_2310377_-|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>CP026964.1|AVG67492.1|2310811_2312179_-|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTQLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>CP026964.1|AVG67493.1|2312204_2312537_-|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>CP026964.1|AVG67494.1|2312523_2313774_-|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSESSTQDANDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGSK
>CP026964.1|AVG67495.1|2313773_2317340_-|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISGAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIALFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>CP026964.1|AVG67496.1|2317486_2318218_-|ribonuclease-3
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>CP026964.1|AVG67497.1|2318333_2318567_-|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK

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Crispr_ID: CP026964_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_10

2318658-2318750

Unclear

Consensus_repeat	Method
CTTATCAATTTATTGATTAGTGTTTCTTA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP026964_10

>merge|CP026964|10|2318658-2318750|CRISPRCasFinder
CTTATCAATTTATTGATTAGTGTTTCTTATGCATGAGCTTTAGCTCAAGCGTTCCTCTAATCTTCTTATCAATTTATTGATTAGTGTTTCTTA

>CP026964|10|10|2318658-2318750|CRISPRCasFinder
CTTATCAATTTATTGATTAGTGTTTCTTA	TGCATGAGCTTTAGCTCAAGCGTTCCTCTAATCTT
CTTATCAATTTATTGATTAGTGTTTCTTA

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67507.1\|2327645_2328287_-\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|224480
CP026964.1\|AVG67501.1\|2320582_2321569_-\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
CP026964.1\|AVG67496.1\|2317486_2318218_-\|ribonuclease-3	unknown	unknown	gnl\|CDD\|234633
CP026964.1\|AVG67493.1\|2312204_2312537_-\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
CP026964.1\|AVG67490.1\|2309410_2309914_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
CP026964.1\|AVG67503.1\|2322348_2324409_-\|DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
CP026964.1\|AVG67489.1\|2308673_2309411_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
CP026964.1\|AVG67488.1\|2308220_2308571_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
CP026964.1\|AVG67494.1\|2312523_2313774_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
CP026964.1\|AVG67502.1\|2321573_2322146_-\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
CP026964.1\|AVG67492.1\|2310811_2312179_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
CP026964.1\|AVG67497.1\|2318333_2318567_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
CP026964.1\|AVG67506.1\|2327076_2327265_+\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
CP026964.1\|AVG67508.1\|2328293_2328938_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
CP026964.1\|AVG67504.1\|2324598_2326245_-\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|224378
CP026964.1\|AVG67505.1\|2326259_2326634_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
CP026964.1\|AVG67500.1\|2319663_2320590_-\|malonyl-CoA-ACP-transacylase	unknown	unknown	gnl\|CDD\|223408
CP026964.1\|AVG67499.1\|2318936_2319671_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
CP026964.1\|AVG67491.1\|2310101_2310377_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
CP026964.1\|AVG67495.1\|2313773_2317340_-\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67507.1\|2327645_2328287_-\|thiamine-diphosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
CP026964.1\|AVG67501.1\|2320582_2321569_-\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.1953e-178
CP026964.1\|AVG67496.1\|2317486_2318218_-\|ribonuclease-3	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
CP026964.1\|AVG67493.1\|2312204_2312537_-\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
CP026964.1\|AVG67490.1\|2309410_2309914_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
CP026964.1\|AVG67503.1\|2322348_2324409_-\|DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
CP026964.1\|AVG67489.1\|2308673_2309411_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.98496e-164
CP026964.1\|AVG67488.1\|2308220_2308571_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
CP026964.1\|AVG67494.1\|2312523_2313774_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
CP026964.1\|AVG67502.1\|2321573_2322146_-\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
CP026964.1\|AVG67492.1\|2310811_2312179_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
CP026964.1\|AVG67497.1\|2318333_2318567_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
CP026964.1\|AVG67506.1\|2327076_2327265_+\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
CP026964.1\|AVG67508.1\|2328293_2328938_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	1.52718e-114
CP026964.1\|AVG67504.1\|2324598_2326245_-\|DAK2-domain-containing-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0
CP026964.1\|AVG67505.1\|2326259_2326634_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
CP026964.1\|AVG67500.1\|2319663_2320590_-\|malonyl-CoA-ACP-transacylase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	3.30125e-134
CP026964.1\|AVG67499.1\|2318936_2319671_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
CP026964.1\|AVG67491.1\|2310101_2310377_-\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
CP026964.1\|AVG67495.1\|2313773_2317340_-\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0

>CP026964.1|AVG67497.1|2318333_2318567_-|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>CP026964.1|AVG67496.1|2317486_2318218_-|ribonuclease-3
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>CP026964.1|AVG67495.1|2313773_2317340_-|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISGAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIALFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>CP026964.1|AVG67494.1|2312523_2313774_-|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSESSTQDANDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGSK
>CP026964.1|AVG67493.1|2312204_2312537_-|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>CP026964.1|AVG67492.1|2310811_2312179_-|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTQLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>CP026964.1|AVG67491.1|2310101_2310377_-|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>CP026964.1|AVG67490.1|2309410_2309914_-|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>CP026964.1|AVG67489.1|2308673_2309411_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>CP026964.1|AVG67488.1|2308220_2308571_-|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>CP026964.1|AVG67499.1|2318936_2319671_-|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>CP026964.1|AVG67500.1|2319663_2320590_-|malonyl-CoA-ACP-transacylase
MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAAKTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDNEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>CP026964.1|AVG67501.1|2320582_2321569_-|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>CP026964.1|AVG67502.1|2321573_2322146_-|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>CP026964.1|AVG67503.1|2322348_2324409_-|DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNNSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYGLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>CP026964.1|AVG67504.1|2324598_2326245_-|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>CP026964.1|AVG67505.1|2326259_2326634_-|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>CP026964.1|AVG67506.1|2327076_2327265_+|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>CP026964.1|AVG67507.1|2327645_2328287_-|thiamine-diphosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>CP026964.1|AVG67508.1|2328293_2328938_-|ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG

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Crispr_ID: CP026964_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_11

2395512-2395763

Orphan

Consensus_repeat	Method
TNTNGGNNCCNCNCCAACTTGCATTGT	CRT

4 spacers

The CRISPR arrays of CP026964_11

>merge|CP026964|11|2395512-2395763|CRT
TCGATGTCCTACCCCAACTTGCATTGTCTGTTGAAATTGGTGACCCAATTTCTCTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTTGGAATTGGTGATCCTATTTCTCTCTGTTGGGGCCCCGCCAACTTGCACATTTTTGTATGCTGACTTTTCGCCAGCTTCTGTGTTGGGCCCCACCCCAACTTGCATTGTCTGTTGAAATTGGTGATCCAATTTCTCTATGTTGGGGCCCCGCCAACTTGCATTGT

>CP026964|11|1|2395512-2395763|CRT
TCGATGTCCTACCCCAACTTGCATTGT	CTGTTGAAATTGGTGACCCAATTTCTCTA
TGTTGGGGCCCCGCCAACTTGCATTGT	TTGTTGGAATTGGTGATCCTATTTCTCTC
TGTTGGGGCCCCGCCAACTTGCACATT	TTTGTATGCTGACTTTTCGCCAGCTTCTGT
GTTGGGCCCCACCCCAACTTGCATTGT	CTGTTGAAATTGGTGATCCAATTTCTCTA
TGTTGGGGCCCCGCCAACTTGCATTGT

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67578.1\|2401228_2402029_-\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
CP026964.1\|AVG67563.1\|2391745_2391925_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67561.1\|2389891_2390617_+\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
CP026964.1\|AVG68074.1\|2394747_2394966_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67565.1\|2392065_2392212_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67571.1\|2396626_2397124_-\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
CP026964.1\|AVG67570.1\|2396122_2396473_-\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|371594
CP026964.1\|AVG67575.1\|2399838_2400006_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67572.1\|2397382_2397889_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67574.1\|2399327_2399645_-\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
CP026964.1\|AVG67576.1\|2400133_2400637_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|223695
CP026964.1\|AVG67568.1\|2395172_2395358_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67577.1\|2400629_2401217_-\|non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl\|CDD\|184835
CP026964.1\|AVG68073.1\|2391657_2391738_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67564.1\|2391884_2392109_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67573.1\|2398559_2398958_+\|FPRL1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
CP026964.1\|AVG67562.1\|2390724_2391441_+\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
CP026964.1\|AVG68075.1\|2398908_2399010_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67567.1\|2394320_2394554_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67566.1\|2392884_2393844_+\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67574.1\|2399327_2399645_-\|fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	1.17077e-21
CP026964.1\|AVG67578.1\|2401228_2402029_-\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	2.38427e-134
CP026964.1\|AVG67576.1\|2400133_2400637_-\|metallophosphoesterase	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	9.91823e-44
CP026964.1\|AVG67566.1\|2392884_2393844_+\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.4958e-141
CP026964.1\|AVG67561.1\|2389891_2390617_+\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
CP026964.1\|AVG67571.1\|2396626_2397124_-\|fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.38388e-27
CP026964.1\|AVG67570.1\|2396122_2396473_-\|fibrinogen-binding-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
CP026964.1\|AVG67562.1\|2390724_2391441_+\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.0861e-152
CP026964.1\|AVG67577.1\|2400629_2401217_-\|non-canonical-purine-NTP-pyrophosphatase	gnl\|CDD\|184835	PRK14822, PRK14822, XTP/dITP diphosphatase.	1.88157e-114
CP026964.1\|AVG67573.1\|2398559_2398958_+\|FPRL1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	6.29479e-75

>CP026964.1|AVG67568.1|2395172_2395358_+|hypothetical-protein
MNKHINKKATKLLEDYKKVQQRKSEETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>CP026964.1|AVG68074.1|2394747_2394966_+|hypothetical-protein
MINFGLIIVPLLTTNDADFVWTSSSLIYMILLTSIILIVYIKTKDSLQLTIFILNIALIILYCAPLLFIYVF
>CP026964.1|AVG67567.1|2394320_2394554_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>CP026964.1|AVG67566.1|2392884_2393844_+|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>CP026964.1|AVG67565.1|2392065_2392212_-|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>CP026964.1|AVG67564.1|2391884_2392109_-|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>CP026964.1|AVG67563.1|2391745_2391925_+|hypothetical-protein
MLHGHFHSVNYYQYNIVEPKTLIYYVLGSIPSFNDSIIIAILYCPMISVLLMRHSNYKV
>CP026964.1|AVG68073.1|2391657_2391738_+|hypothetical-protein
MLGPRQLAHYCKLTFRQLLCWGPAYN
>CP026964.1|AVG67562.1|2390724_2391441_+|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKGRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>CP026964.1|AVG67561.1|2389891_2390617_+|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>CP026964.1|AVG67570.1|2396122_2396473_-|fibrinogen-binding-protein
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>CP026964.1|AVG67571.1|2396626_2397124_-|fibrinogen-binding-protein
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>CP026964.1|AVG67572.1|2397382_2397889_-|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>CP026964.1|AVG67573.1|2398559_2398958_+|FPRL1-inhibitory-protein
MKKNITKVIIASTVIATGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERADKLIKEADEKNEHYKGKTVEDLYVIAKKMGKGNTIAVVKIKDGGKNGYYTFDITRPLEEHRKNIPVVKNGEIDSITWY
>CP026964.1|AVG68075.1|2398908_2399010_+|hypothetical-protein
MFQWLKTAKSIRLLGIKKHTELNSCTPNVRKQC
>CP026964.1|AVG67574.1|2399327_2399645_-|fibrinogen-binding-protein
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKVEKYNEYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>CP026964.1|AVG67575.1|2399838_2400006_-|hypothetical-protein
MKRIVILENVIVDDPIRLNHVDYLVKSVLLKSIKLRFQEVRKFEILVKIMNRIHI
>CP026964.1|AVG67576.1|2400133_2400637_-|metallophosphoesterase
MSKWIIVSDNHTESGVLYQIYEMHPDADVYLHLGDSEFAYDDTELSLFNRVKGNCDFYPEFENEAVAKYNDVKAFYTHGHLYQVNRTRDLLAEKGLELGCLFAFYGHTHVAKYEYINGVHVINPGSISQSRSSMEETYAEVIIDDQTLHGTINFKNRHHETISHTTF
>CP026964.1|AVG67577.1|2400629_2401217_-|non-canonical-purine-NTP-pyrophosphatase
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV
>CP026964.1|AVG67578.1|2401228_2402029_-|glutamate-racemase
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND

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Crispr_ID: CP026964_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_12

2476061-2476153

Orphan

Consensus_repeat	Method
CCTTACAACTTTTAGTTGTTAGGGGATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_12

>merge|CP026964|12|2476061-2476153|CRISPRCasFinder
CCTTACAACTTTTAGTTGTTAGGGGATTTTATGCATGTGCTCGGCGCATGTGTCCCTCTTCTTCCTTACAACTTTTAGTTGTTAGGGGCTTTT

>CP026964|12|11|2476061-2476153|CRISPRCasFinder
CCTTACAACTTTTAGTTGTTAGGGGATTTT	ATGCATGTGCTCGGCGCATGTGTCCCTCTTCTT
CCTTACAACTTTTAGTTGTTAGGGGCTTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67663.1\|2485503_2487693_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
CP026964.1\|AVG67662.1\|2484040_2485525_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
CP026964.1\|AVG67655.1\|2476634_2477210_+\|thiamine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227065
CP026964.1\|AVG67649.1\|2471856_2472123_-\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
CP026964.1\|AVG67659.1\|2480957_2482436_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
CP026964.1\|AVG67647.1\|2469665_2469899_+\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
CP026964.1\|AVG67646.1\|2468106_2469468_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
CP026964.1\|AVG67652.1\|2474469_2475765_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67658.1\|2479688_2480936_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
CP026964.1\|AVG67653.1\|2475916_2476051_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67645.1\|2467090_2468110_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
CP026964.1\|AVG67664.1\|2487685_2488357_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
CP026964.1\|AVG67656.1\|2477224_2478625_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
CP026964.1\|AVG67651.1\|2472872_2474045_-\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
CP026964.1\|AVG67648.1\|2470135_2471854_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
CP026964.1\|AVG67660.1\|2482450_2483017_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
CP026964.1\|AVG68077.1\|2474245_2474449_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67657.1\|2478617_2479424_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP026964.1\|AVG67661.1\|2483019_2484048_-\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
CP026964.1\|AVG67650.1\|2472276_2472819_-\|DUF697-domain-containing-protein	unknown	unknown	gnl\|CDD\|368297

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67663.1\|2485503_2487693_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
CP026964.1\|AVG67662.1\|2484040_2485525_-\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
CP026964.1\|AVG67655.1\|2476634_2477210_+\|thiamine-ABC-transporter-permease	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
CP026964.1\|AVG67659.1\|2480957_2482436_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
CP026964.1\|AVG67647.1\|2469665_2469899_+\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.21197e-16
CP026964.1\|AVG67646.1\|2468106_2469468_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
CP026964.1\|AVG67649.1\|2471856_2472123_-\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
CP026964.1\|AVG67658.1\|2479688_2480936_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
CP026964.1\|AVG67645.1\|2467090_2468110_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.67944e-76
CP026964.1\|AVG67664.1\|2487685_2488357_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.73525e-140
CP026964.1\|AVG67656.1\|2477224_2478625_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.87437e-64
CP026964.1\|AVG67651.1\|2472872_2474045_-\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
CP026964.1\|AVG67648.1\|2470135_2471854_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
CP026964.1\|AVG67660.1\|2482450_2483017_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	2.03517e-91
CP026964.1\|AVG67657.1\|2478617_2479424_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.19598e-29
CP026964.1\|AVG67661.1\|2483019_2484048_-\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
CP026964.1\|AVG67650.1\|2472276_2472819_-\|DUF697-domain-containing-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00844137

>CP026964.1|AVG67653.1|2475916_2476051_+|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>CP026964.1|AVG67652.1|2474469_2475765_-|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>CP026964.1|AVG68077.1|2474245_2474449_+|hypothetical-protein
MILQMDNFSTILFALKLCIQFSILNSHHLNQSNLVTKKVLSINFIDLYLNKLEIYLTYSVHIKMFNR
>CP026964.1|AVG67651.1|2472872_2474045_-|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>CP026964.1|AVG67650.1|2472276_2472819_-|DUF697-domain-containing-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>CP026964.1|AVG67649.1|2471856_2472123_-|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>CP026964.1|AVG67648.1|2470135_2471854_-|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>CP026964.1|AVG67647.1|2469665_2469899_+|glutaredoxin-family-protein
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>CP026964.1|AVG67646.1|2468106_2469468_-|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>CP026964.1|AVG67645.1|2467090_2468110_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>CP026964.1|AVG67655.1|2476634_2477210_+|thiamine-ABC-transporter-permease
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>CP026964.1|AVG67656.1|2477224_2478625_+|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>CP026964.1|AVG67657.1|2478617_2479424_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>CP026964.1|AVG67658.1|2479688_2480936_-|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFAIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKNGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>CP026964.1|AVG67659.1|2480957_2482436_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>CP026964.1|AVG67660.1|2482450_2483017_-|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVSLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>CP026964.1|AVG67661.1|2483019_2484048_-|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDSSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIMKNESTAIELLGV
>CP026964.1|AVG67662.1|2484040_2485525_-|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>CP026964.1|AVG67663.1|2485503_2487693_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>CP026964.1|AVG67664.1|2487685_2488357_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNKKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV

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Crispr_ID: CP026964_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_13

2654339-2654420

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_13

>merge|CP026964|13|2654339-2654420|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGCTCCCCAATTTCTCTGTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP026964|13|12|2654339-2654420|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGCTCCCCAATTTCTCTGTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67840.1\|2660366_2660750_+\|kinase	unknown	unknown	gnl\|CDD\|378054
CP026964.1\|AVG67838.1\|2658917_2659295_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|224023
CP026964.1\|AVG67829.1\|2647331_2647856_-\|inactive-signal-peptidase-IA	unknown	unknown	gnl\|CDD\|274044
CP026964.1\|AVG67843.1\|2664040_2665537_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP026964.1\|AVG67832.1\|2650442_2651648_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP026964.1\|AVG67828.1\|2646740_2647316_-\|signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP026964.1\|AVG67839.1\|2659709_2660303_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
CP026964.1\|AVG67827.1\|2643104_2646581_-\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	unknown	unknown	gnl\|CDD\|213736
CP026964.1\|AVG67841.1\|2660880_2663286_+\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
CP026964.1\|AVG68081.1\|2663718_2664048_+\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP026964.1\|AVG67825.1\|2638382_2639285_-\|FAA-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP026964.1\|AVG67835.1\|2654577_2655822_-\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP026964.1\|AVG67826.1\|2639450_2643104_-\|ATP-dependent-helicase/nuclease-subunit-A	unknown	unknown	gnl\|CDD\|274299
CP026964.1\|AVG67830.1\|2647860_2648436_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP026964.1\|AVG67837.1\|2657428_2658556_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
CP026964.1\|AVG67842.1\|2663278_2663707_+\|Na+/H+-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP026964.1\|AVG67834.1\|2653258_2654188_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
CP026964.1\|AVG67833.1\|2651637_2653017_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP026964.1\|AVG67831.1\|2648760_2650092_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP026964.1\|AVG67836.1\|2655930_2657121_-\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67840.1\|2660366_2660750_+\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP026964.1\|AVG67838.1\|2658917_2659295_-\|general-stress-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP026964.1\|AVG67829.1\|2647331_2647856_-\|inactive-signal-peptidase-IA	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.81012e-49
CP026964.1\|AVG67843.1\|2664040_2665537_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP026964.1\|AVG67832.1\|2650442_2651648_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP026964.1\|AVG67828.1\|2646740_2647316_-\|signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	7.44791e-54
CP026964.1\|AVG67839.1\|2659709_2660303_-\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP026964.1\|AVG67827.1\|2643104_2646581_-\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP026964.1\|AVG67841.1\|2660880_2663286_+\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP026964.1\|AVG68081.1\|2663718_2664048_+\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
CP026964.1\|AVG67825.1\|2638382_2639285_-\|FAA-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
CP026964.1\|AVG67835.1\|2654577_2655822_-\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP026964.1\|AVG67826.1\|2639450_2643104_-\|ATP-dependent-helicase/nuclease-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP026964.1\|AVG67830.1\|2647860_2648436_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP026964.1\|AVG67837.1\|2657428_2658556_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP026964.1\|AVG67842.1\|2663278_2663707_+\|Na+/H+-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP026964.1\|AVG67834.1\|2653258_2654188_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP026964.1\|AVG67833.1\|2651637_2653017_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP026964.1\|AVG67831.1\|2648760_2650092_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP026964.1\|AVG67836.1\|2655930_2657121_-\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0

>CP026964.1|AVG67834.1|2653258_2654188_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP026964.1|AVG67833.1|2651637_2653017_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLINQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP026964.1|AVG67832.1|2650442_2651648_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNSMLHGGYSNEQ
>CP026964.1|AVG67831.1|2648760_2650092_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP026964.1|AVG67830.1|2647860_2648436_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP026964.1|AVG67829.1|2647331_2647856_-|inactive-signal-peptidase-IA
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP026964.1|AVG67828.1|2646740_2647316_-|signal-peptidase-IB
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP026964.1|AVG67827.1|2643104_2646581_-|ATP-dependent-helicase/deoxyribonuclease-subunit-B
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDVLQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVFLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYIAMTRARQDVTFSYRLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP026964.1|AVG67826.1|2639450_2643104_-|ATP-dependent-helicase/nuclease-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP026964.1|AVG67825.1|2638382_2639285_-|FAA-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>CP026964.1|AVG67835.1|2654577_2655822_-|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP026964.1|AVG67836.1|2655930_2657121_-|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP026964.1|AVG67837.1|2657428_2658556_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPGGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP026964.1|AVG67838.1|2658917_2659295_-|general-stress-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP026964.1|AVG67839.1|2659709_2660303_-|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP026964.1|AVG67840.1|2660366_2660750_+|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP026964.1|AVG67841.1|2660880_2663286_+|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP026964.1|AVG67842.1|2663278_2663707_+|Na+/H+-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP026964.1|AVG68081.1|2663718_2664048_+|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP026964.1|AVG67843.1|2664040_2665537_+|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Crispr_ID: CP026964_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_14

2703162-2703243

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_14

>merge|CP026964|14|2703162-2703243|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCTCAATTTCTACAGACAATGCAAGTTGGGG

>CP026964|14|13|2703162-2703243|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCTCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67894.1\|2705911_2706451_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
CP026964.1\|AVG67890.1\|2704226_2704340_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67885.1\|2699967_2700663_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
CP026964.1\|AVG67898.1\|2708867_2709485_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
CP026964.1\|AVG67882.1\|2697496_2698348_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
CP026964.1\|AVG67887.1\|2701930_2702227_-\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP026964.1\|AVG68082.1\|2702815_2702953_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67888.1\|2702219_2702606_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
CP026964.1\|AVG67881.1\|2696407_2697169_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
CP026964.1\|AVG67892.1\|2704941_2705298_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
CP026964.1\|AVG67880.1\|2695002_2696310_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
CP026964.1\|AVG67886.1\|2700655_2701681_-\|methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP026964.1\|AVG67891.1\|2704403_2704784_-\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|234918
CP026964.1\|AVG67893.1\|2705441_2705762_+\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP026964.1\|AVG67896.1\|2707397_2707820_+\|organic-hydroperoxide-reductase-OsmC/OhrA	unknown	unknown	gnl\|CDD\|274649
CP026964.1\|AVG67884.1\|2699128_2699950_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
CP026964.1\|AVG67895.1\|2706533_2707250_-\|3-dehydroquinase	unknown	unknown	gnl\|CDD\|184156
CP026964.1\|AVG67897.1\|2708218_2708713_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
CP026964.1\|AVG67883.1\|2698580_2698775_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP026964.1\|AVG67889.1\|2703346_2704225_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67894.1\|2705911_2706451_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.62265e-48
CP026964.1\|AVG67885.1\|2699967_2700663_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
CP026964.1\|AVG67898.1\|2708867_2709485_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.6558e-60
CP026964.1\|AVG67882.1\|2697496_2698348_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	9.12578e-76
CP026964.1\|AVG67887.1\|2701930_2702227_-\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP026964.1\|AVG67888.1\|2702219_2702606_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP026964.1\|AVG67881.1\|2696407_2697169_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP026964.1\|AVG67892.1\|2704941_2705298_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP026964.1\|AVG67880.1\|2695002_2696310_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	9.26601e-136
CP026964.1\|AVG67886.1\|2700655_2701681_-\|methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
CP026964.1\|AVG67891.1\|2704403_2704784_-\|glycine-cleavage-system-protein-H	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.95269e-69
CP026964.1\|AVG67893.1\|2705441_2705762_+\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.31384e-24
CP026964.1\|AVG67896.1\|2707397_2707820_+\|organic-hydroperoxide-reductase-OsmC/OhrA	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.70812e-60
CP026964.1\|AVG67884.1\|2699128_2699950_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.93804e-112
CP026964.1\|AVG67895.1\|2706533_2707250_-\|3-dehydroquinase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.05028e-146
CP026964.1\|AVG67897.1\|2708218_2708713_+\|N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP026964.1\|AVG67883.1\|2698580_2698775_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
CP026964.1\|AVG67889.1\|2703346_2704225_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	5.66518e-74

>CP026964.1|AVG68082.1|2702815_2702953_-|hypothetical-protein
MSKEKVFLYVGAPQLAHYCKLTFRQLLCWGPAIIEKFVIGVFSFG
>CP026964.1|AVG67888.1|2702219_2702606_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP026964.1|AVG67887.1|2701930_2702227_-|thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP026964.1|AVG67886.1|2700655_2701681_-|methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP026964.1|AVG67885.1|2699967_2700663_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP026964.1|AVG67884.1|2699128_2699950_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKVKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP026964.1|AVG67883.1|2698580_2698775_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP026964.1|AVG67882.1|2697496_2698348_+|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGFYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP026964.1|AVG67881.1|2696407_2697169_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP026964.1|AVG67880.1|2695002_2696310_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVIGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>CP026964.1|AVG67889.1|2703346_2704225_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMVLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP026964.1|AVG67890.1|2704226_2704340_-|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>CP026964.1|AVG67891.1|2704403_2704784_-|glycine-cleavage-system-protein-H
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>CP026964.1|AVG67892.1|2704941_2705298_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP026964.1|AVG67893.1|2705441_2705762_+|thioredoxin
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYKDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP026964.1|AVG67894.1|2705911_2706451_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLSGFLYLTDLEEDMPKAPRKNRNLITLY
>CP026964.1|AVG67895.1|2706533_2707250_-|3-dehydroquinase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>CP026964.1|AVG67896.1|2707397_2707820_+|organic-hydroperoxide-reductase-OsmC/OhrA
MAIHYETKATNVGGRKGHVYTDDRALDIDIVSPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP026964.1|AVG67897.1|2708218_2708713_+|N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP026964.1|AVG67898.1|2708867_2709485_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIIAAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGEMVGSIDKTGKLLTIINKLSSIIIIIVALMILQKLIQLLF

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Crispr_ID: CP026964_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026964_15

2750587-2750667

Unclear

Consensus_repeat	Method
AGTTGGCGGGGCCCCAACATAAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026964_15

>merge|CP026964|15|2750587-2750667|CRISPRCasFinder
AGTTGGCGGGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACATAAAGAA

>CP026964|15|14|2750587-2750667|CRISPRCasFinder
AGTTGGCGGGGCCCCAACATAAAGAA	TTTCGAAAAGAAATTCTACAAACAATGCA
AGTTGGCGGGGCCCCAACATAAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP026964.1\|AVG67947.1\|2759794_2762326_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP026964.1\|AVG67931.1\|2742962_2743958_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
CP026964.1\|AVG67942.1\|2756297_2756948_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
CP026964.1\|AVG67937.1\|2748572_2749412_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP026964.1\|AVG67943.1\|2757121_2757961_-\|peptidase-M23	unknown	unknown	gnl\|CDD\|226451
CP026964.1\|AVG67941.1\|2756064_2756301_-\|DUF2198-domain-containing-protein	unknown	unknown	gnl\|CDD\|227234
CP026964.1\|AVG67945.1\|2758369_2759480_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP026964.1\|AVG67935.1\|2746632_2748072_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP026964.1\|AVG67946.1\|2759648_2759753_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67932.1\|2743954_2744866_-\|RNase-adaptor-protein-RapZ	unknown	unknown	gnl\|CDD\|224574
CP026964.1\|AVG67930.1\|2741907_2742852_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
CP026964.1\|AVG67936.1\|2748079_2748565_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP026964.1\|AVG67939.1\|2750956_2753803_-\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP026964.1\|AVG67948.1\|2762739_2763312_-\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP026964.1\|AVG67944.1\|2758108_2758216_-\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67929.1\|2740747_2741335_-\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP026964.1\|AVG67934.1\|2745630_2746566_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP026964.1\|AVG67940.1\|2753810_2755796_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
CP026964.1\|AVG67933.1\|2745060_2745285_+\|hypothetical-protein	unknown	unknown	unknown
CP026964.1\|AVG67938.1\|2749417_2750350_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459

Protein	Function_ID	Function_description	E-value
CP026964.1\|AVG67947.1\|2759794_2762326_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP026964.1\|AVG67931.1\|2742962_2743958_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP026964.1\|AVG67942.1\|2756297_2756948_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP026964.1\|AVG67937.1\|2748572_2749412_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
CP026964.1\|AVG67943.1\|2757121_2757961_-\|peptidase-M23	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
CP026964.1\|AVG67941.1\|2756064_2756301_-\|DUF2198-domain-containing-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP026964.1\|AVG67945.1\|2758369_2759480_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP026964.1\|AVG67935.1\|2746632_2748072_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP026964.1\|AVG67932.1\|2743954_2744866_-\|RNase-adaptor-protein-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP026964.1\|AVG67930.1\|2741907_2742852_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP026964.1\|AVG67936.1\|2748079_2748565_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
CP026964.1\|AVG67939.1\|2750956_2753803_-\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP026964.1\|AVG67948.1\|2762739_2763312_-\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP026964.1\|AVG67929.1\|2740747_2741335_-\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP026964.1\|AVG67934.1\|2745630_2746566_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP026964.1\|AVG67940.1\|2753810_2755796_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP026964.1\|AVG67938.1\|2749417_2750350_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170

>CP026964.1|AVG67938.1|2749417_2750350_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP026964.1|AVG67937.1|2748572_2749412_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP026964.1|AVG67936.1|2748079_2748565_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP026964.1|AVG67935.1|2746632_2748072_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP026964.1|AVG67934.1|2745630_2746566_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>CP026964.1|AVG67933.1|2745060_2745285_+|hypothetical-protein
MKTRLQQAFFNSSQGPQHREFRKEILQAMRVGVWAPTQRISKRISTDNASWRGPNTEAYEKSAYDNVRVGVGQR
>CP026964.1|AVG67932.1|2743954_2744866_-|RNase-adaptor-protein-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP026964.1|AVG67931.1|2742962_2743958_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP026964.1|AVG67930.1|2741907_2742852_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP026964.1|AVG67929.1|2740747_2741335_-|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP026964.1|AVG67939.1|2750956_2753803_-|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP026964.1|AVG67940.1|2753810_2755796_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP026964.1|AVG67941.1|2756064_2756301_-|DUF2198-domain-containing-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP026964.1|AVG67942.1|2756297_2756948_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP026964.1|AVG67943.1|2757121_2757961_-|peptidase-M23
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP026964.1|AVG67944.1|2758108_2758216_-|hypothetical-protein
MYLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>CP026964.1|AVG67945.1|2758369_2759480_-|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP026964.1|AVG67946.1|2759648_2759753_-|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>CP026964.1|AVG67947.1|2759794_2762326_-|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP026964.1|AVG67948.1|2762739_2763312_-|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	474007-474022	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	474063-474078	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	489290-489305	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	489562-489577	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	971758-971773	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1211757-1211772	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1581564-1581579	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1918919-1918934	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2093631-2093646	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2179082-2179097	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2183479-2183494	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2391682-2391697	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2492333-2492348	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2702890-2702905	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2737983-2737998	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2738039-2738054	0	1.0
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	474083-474108	0	1.0
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	474119-474134	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1592375-1592390	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1741714-1741729	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1798722-1798737	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	1904372-1904387	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2136897-2136912	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2359008-2359023	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2745244-2745259	1	0.938
CP026964_2	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	CP026964.1	2782141-2782156	1	0.938
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	474027-474052	1	0.962
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	2702860-2702885	1	0.962
CP026964_14	14.1\|2703186\|34\|CP026964\|CRISPRCasFinder	2703186-2703219	34	CP026964.1	2093659-2093692	1	0.971
CP026964_14	14.1\|2703186\|34\|CP026964\|CRISPRCasFinder	2703186-2703219	34	CP026964.1	2183433-2183466	1	0.971
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	396395-396423	1	0.966
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	1741766-1741794	1	0.966
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	2053623-2053651	1	0.966
CP026964_5	5.1\|1246047\|26\|CP026964\|CRISPRCasFinder	1246047-1246072	26	CP026964.1	2391702-2391727	2	0.923
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	2738009-2738034	2	0.923
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	2782105-2782130	2	0.923
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	2782161-2782186	2	0.923
CP026964_9	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	CP026964.1	2782217-2782242	2	0.923
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	CP026964.1	1477610-1477638	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	489338-489366	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	597386-597414	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	597444-597472	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	1918967-1918995	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	2391623-2391651	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	2654405-2654433	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	2703149-2703177	2	0.931
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	CP026964.1	2745179-2745207	2	0.931

1. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 474007-474022, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

2. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 474063-474078, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

3. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 489290-489305, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

4. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 489562-489577, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

5. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 971758-971773, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

6. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1211757-1211772, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

7. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1581564-1581579, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

8. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1918919-1918934, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

9. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2093631-2093646, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

10. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2179082-2179097, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

11. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2183479-2183494, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

12. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2391682-2391697, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

13. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2492333-2492348, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

14. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2702890-2702905, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

15. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2737983-2737998, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

16. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2738039-2738054, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

17. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 474083-474108, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

18. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 474119-474134, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcatacaataatg	Protospacer
***** **********

19. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1592375-1592390, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacgataatg	Protospacer
*********.******

20. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1741714-1741729, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagctttcaataatg	Protospacer
******* ********

21. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1798722-1798737, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttactataatg	Protospacer
********* ******

22. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 1904372-1904387, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacgataatg	Protospacer
*********.******

23. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2136897-2136912, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacaacaatg	Protospacer
***********.****

24. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2359008-2359023, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacaacaatg	Protospacer
***********.****

25. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2745244-2745259, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacgataatg	Protospacer
*********.******

26. spacer 2.2|806524|16|CP026964|PILER-CR matches to position: 2782141-2782156, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagctaacaataatg	Protospacer
****** *********

27. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 474027-474052, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

28. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 2702860-2702885, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

29. spacer 14.1|2703186|34|CP026964|CRISPRCasFinder matches to position: 2093659-2093692, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

30. spacer 14.1|2703186|34|CP026964|CRISPRCasFinder matches to position: 2183433-2183466, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

31. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 396395-396423, mismatch: 1, identity: 0.966

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaagcaatgca	Protospacer
*********************.*******

32. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 1741766-1741794, mismatch: 1, identity: 0.966

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacagacaatgca	Protospacer
********************.********

33. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 2053623-2053651, mismatch: 1, identity: 0.966

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacagacaatgca	Protospacer
********************.********

34. spacer 5.1|1246047|26|CP026964|CRISPRCasFinder matches to position: 2391702-2391727, mismatch: 2, identity: 0.923

cggggccccaacatagaaggtgacga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
*************.***** ******

35. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 2738009-2738034, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctgtgttggggccccg	Protospacer
***.********.*************

36. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 2782105-2782130, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttttatgttggggccccg	Protospacer
***** ****.***************

37. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 2782161-2782186, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtctgcttctatgttggggccccg	Protospacer
***.* ********************

38. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to position: 2782217-2782242, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ******.*************

39. spacer 11.4|2395708|29|CP026964|CRT matches to position: 1477610-1477638, mismatch: 2, identity: 0.931

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
ctgtagaaattggtgttccaatttctcta	Protospacer
**** ********** *************

40. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 489338-489366, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

41. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 597386-597414, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

42. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 597444-597472, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

43. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 1918967-1918995, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

44. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 2391623-2391651, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcaaaaagaaattctacagacaatgca	Protospacer
****.***************.********

45. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 2654405-2654433, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

46. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 2703149-2703177, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

47. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to position: 2745179-2745207, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaatttctacagacaatgca	Protospacer
************ *******.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026964_7	7.1\|1798780\|27\|CP026964\|CRISPRCasFinder	1798780-1798806	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815
CP026964_11	11.1\|2395539\|29\|CP026964\|CRT	2395539-2395567	29	KY971610	Pseudomonas phage PspYZU05, complete genome	73941-73969	6	0.793
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MH051913	Enterobacteria phage vB_EcoM_IME281, complete genome	39126-39154	6	0.793
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MT682711	Escherichia phage vB_EcoM_FB, complete genome	135624-135652	6	0.793
CP026964_8	8.4\|1884666\|29\|CP026964\|PILER-CR	1884666-1884694	29	MT889391	Mycobacterium phage MiniMac, complete genome	11249-11277	7	0.759
CP026964_8	8.4\|1884666\|29\|CP026964\|PILER-CR	1884666-1884694	29	MT889383	Mycobacterium phage MiniLon, complete genome	11248-11276	7	0.759
CP026964_8	8.4\|1884666\|29\|CP026964\|PILER-CR	1884666-1884694	29	KT281791	Mycobacterium phage Lolly9, complete genome	11248-11276	7	0.759
CP026964_11	11.1\|2395539\|29\|CP026964\|CRT	2395539-2395567	29	MT782071	Escherichia phage JN02, complete genome	83703-83731	7	0.759
CP026964_11	11.2\|2395595\|29\|CP026964\|CRT	2395595-2395623	29	NZ_LR215032	Mycoplasma gallopavonis strain NCTC10186 plasmid 2	268762-268790	7	0.759
CP026964_11	11.2\|2395595\|29\|CP026964\|CRT	2395595-2395623	29	MN856116	Myoviridae sp. isolate 525, complete genome	4988-5016	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MK295203	Escherichia phage vB_EcoM_005, complete genome	6681-6709	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MH051917	Enterobacteria phage vB_EcoM_IME341, complete genome	39726-39754	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	NC_014260	Enterobacteria phage IME08, complete genome	136112-136140	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MK234886	Escherichia phage AnYang, complete genome	100563-100591	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	HM071924	Enterobacteria phage IME08, complete sequence	136112-136140	7	0.759
CP026964_15	15.1\|2750613\|29\|CP026964\|CRISPRCasFinder	2750613-2750641	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	MN175386	Klebsiella pneumoniae strain KP-13-14 plasmid pKP-13-14-NDM-9, complete sequence	198297-198325	8	0.724
CP026964_11	11.4\|2395708\|29\|CP026964\|CRT	2395708-2395736	29	KY653116	Staphylococcus phage IME1318_01, complete genome	21349-21377	8	0.724
CP026964_6	6.1\|1357553\|32\|CP026964\|CRISPRCasFinder	1357553-1357584	32	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	41454-41485	9	0.719
CP026964_8	8.2\|1884645\|32\|CP026964\|CRISPRCasFinder	1884645-1884676	32	MT889383	Mycobacterium phage MiniLon, complete genome	11248-11279	9	0.719
CP026964_8	8.2\|1884645\|32\|CP026964\|CRISPRCasFinder	1884645-1884676	32	KT281791	Mycobacterium phage Lolly9, complete genome	11248-11279	9	0.719
CP026964_6	6.1\|1357553\|32\|CP026964\|CRISPRCasFinder	1357553-1357584	32	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	296489-296520	10	0.688
CP026964_11	11.3\|2395651\|30\|CP026964\|CRT	2395651-2395680	30	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	166038-166067	10	0.667

1. spacer 7.1|1798780|27|CP026964|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

ggtctgtagaatttcttttcgaaattc	CRISPR spacer
gatctgtataatttcttttggaaatag	Protospacer
*.****** ********** *****

2. spacer 11.1|2395539|29|CP026964|CRT matches to KY971610 (Pseudomonas phage PspYZU05, complete genome) position: , mismatch: 6, identity: 0.793

ctgttgaaattggtgacccaatttctcta	CRISPR spacer
ctgttcaaattggtgaccctatttcatgt	Protospacer
***** ************* ***** .

3. spacer 11.4|2395708|29|CP026964|CRT matches to MH051913 (Enterobacteria phage vB_EcoM_IME281, complete genome) position: , mismatch: 6, identity: 0.793

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggca	Protospacer
* **************** ****.*  .*

4. spacer 11.4|2395708|29|CP026964|CRT matches to MT682711 (Escherichia phage vB_EcoM_FB, complete genome) position: , mismatch: 6, identity: 0.793

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggca	Protospacer
* **************** ****.*  .*

5. spacer 8.4|1884666|29|CP026964|PILER-CR matches to MT889391 (Mycobacterium phage MiniMac, complete genome) position: , mismatch: 7, identity: 0.759

agctgaccaaaagtcagatttcaataatg	CRISPR spacer
tcaggacctaaagtcagatttcaagaagg	Protospacer
    **** *************** ** *

6. spacer 8.4|1884666|29|CP026964|PILER-CR matches to MT889383 (Mycobacterium phage MiniLon, complete genome) position: , mismatch: 7, identity: 0.759

agctgaccaaaagtcagatttcaataatg	CRISPR spacer
tcaggacctaaagtcagatttcaagaagg	Protospacer
    **** *************** ** *

7. spacer 8.4|1884666|29|CP026964|PILER-CR matches to KT281791 (Mycobacterium phage Lolly9, complete genome) position: , mismatch: 7, identity: 0.759

agctgaccaaaagtcagatttcaataatg	CRISPR spacer
tcaggacctaaagtcagatttcaagaagg	Protospacer
    **** *************** ** *

8. spacer 11.1|2395539|29|CP026964|CRT matches to MT782071 (Escherichia phage JN02, complete genome) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgacccaatttctcta	CRISPR spacer
ccgttcaaatgggtgacccaatttcatgc	Protospacer
*.*** **** ************** .

9. spacer 11.2|2395595|29|CP026964|CRT matches to NZ_LR215032 (Mycoplasma gallopavonis strain NCTC10186 plasmid 2) position: , mismatch: 7, identity: 0.759

ttgttggaattggtgatcctatttctctc	CRISPR spacer
ttgttggaattggtggtccaattaatgaa	Protospacer
***************.*** ***  *

10. spacer 11.2|2395595|29|CP026964|CRT matches to MN856116 (Myoviridae sp. isolate 525, complete genome) position: , mismatch: 7, identity: 0.759

ttgttggaattggtgatcctatttctctc	CRISPR spacer
ttgttggaattggttttcctattgtttct	Protospacer
**************  ******* .*...

11. spacer 11.4|2395708|29|CP026964|CRT matches to MK295203 (Escherichia phage vB_EcoM_005, complete genome) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggcg	Protospacer
* **************** ****.*  ..

12. spacer 11.4|2395708|29|CP026964|CRT matches to MH051917 (Enterobacteria phage vB_EcoM_IME341, complete genome) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggcg	Protospacer
* **************** ****.*  ..

13. spacer 11.4|2395708|29|CP026964|CRT matches to NC_014260 (Enterobacteria phage IME08, complete genome) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggcg	Protospacer
* **************** ****.*  ..

14. spacer 11.4|2395708|29|CP026964|CRT matches to MK234886 (Escherichia phage AnYang, complete genome) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggcg	Protospacer
* **************** ****.*  ..

15. spacer 11.4|2395708|29|CP026964|CRT matches to HM071924 (Enterobacteria phage IME08, complete sequence) position: , mismatch: 7, identity: 0.759

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
cggttgaaattggtgatcgaattccggcg	Protospacer
* **************** ****.*  ..

16. spacer 15.1|2750613|29|CP026964|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
cacttagaagaaatcctacaaacaatgca	Protospacer
. .. *.*******.**************

17. spacer 11.4|2395708|29|CP026964|CRT matches to MN175386 (Klebsiella pneumoniae strain KP-13-14 plasmid pKP-13-14-NDM-9, complete sequence) position: , mismatch: 8, identity: 0.724

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
agcctgaaattgatgatgcaatttctcgc	Protospacer
   .********.**** *********

18. spacer 11.4|2395708|29|CP026964|CRT matches to KY653116 (Staphylococcus phage IME1318_01, complete genome) position: , mismatch: 8, identity: 0.724

ctgttgaaattggtgatccaatttctcta	CRISPR spacer
agcgtgaaattggtggtccaatatctcgt	Protospacer
    ***********.****** ****

19. spacer 6.1|1357553|32|CP026964|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 9, identity: 0.719

aaaagtaggagcgcctgcgctaagcgcatgca	CRISPR spacer
tggaggtggagcgcctgcgcaaggcgcatgag	Protospacer
 ..**  ************* *.******* .

20. spacer 8.2|1884645|32|CP026964|CRISPRCasFinder matches to MT889383 (Mycobacterium phage MiniLon, complete genome) position: , mismatch: 9, identity: 0.719

agctgaccaaaagtcagatttcaataatgtgc	CRISPR spacer
tcaggacctaaagtcagatttcaagaaggggt	Protospacer
    **** *************** ** * *.

21. spacer 8.2|1884645|32|CP026964|CRISPRCasFinder matches to KT281791 (Mycobacterium phage Lolly9, complete genome) position: , mismatch: 9, identity: 0.719

agctgaccaaaagtcagatttcaataatgtgc	CRISPR spacer
tcaggacctaaagtcagatttcaagaaggggt	Protospacer
    **** *************** ** * *.

22. spacer 6.1|1357553|32|CP026964|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

aaaagtaggagcgcctgcgctaagcgcatgca	CRISPR spacer
tcgaagccgagcgcctgcgcgtagcgcatgcg	Protospacer
  .*.   ************  *********.

23. spacer 11.3|2395651|30|CP026964|CRT matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 10, identity: 0.667

tttgtatgctgacttttcgccagcttctgt	CRISPR spacer
aaatcggactgatttttcgccagcttctgc	Protospacer
    .. .****.****************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5814 : 13635

Pandoravirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG65350.1\|5814_6966_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1
AVG65351.1\|6949_7543_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
AVG65352.1\|7893_8562_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AVG65353.1\|8563_8983_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
AVG65354.1\|8986_9700_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AVG65355.1\|9798_10383_+	hypothetical protein	NA	NA	NA	NA
AVG65356.1\|10662_11103_+	hypothetical protein	NA	NA	NA	NA
AVG65357.1\|11445_11919_+	DoxX family protein	NA	NA	NA	NA
AVG65358.1\|11893_12580_+	DNA-binding response regulator	NA	NA	NA	NA
AVG65359.1\|12579_13635_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

DBSCAN-SWA_2

1479823 : 1537614

Staphylococcus_phage(95.38%)

terminase,tail,portal,protease,holin,head,integrase,capsid

attL 1483778:1483795|attR 1530234:1530251

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG66714.1\|1479823_1480567_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVG66715.1\|1480741_1481026_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
AVG66716.1\|1481101_1482718_+	molecular chaperone GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
AVG66717.1\|1483419_1483632_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
AVG66718.1\|1483628_1484219_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.2e-96	94.7
1483778:1483795	attL	NA	NA	NA	NA
AVG68041.1\|1484535_1484973_+	hypothetical protein	NA	NA	NA	NA
AVG66719.1\|1485078_1485522_+	N-acetyltransferase	NA	NA	NA	NA
AVG66720.1\|1486375_1487683_-	TrkH family potassium uptake protein	NA	NA	NA	NA
AVG66721.1\|1487843_1488755_+	ferrichrome ABC transporter substrate-binding protein	NA	NA	NA	NA
AVG66722.1\|1488816_1489662_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AVG66723.1\|1490033_1491257_-	succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AVG66724.1\|1491692_1492745_+	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.6e-35	32.1
AVG66725.1\|1492766_1493783_+	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
AVG66726.1\|1494901_1495939_-\|integrase	site-specific integrase	E9LT82	Staphylococcus_phage	2.6e-195	100.0
AVG66727.1\|1496022_1496751_-	exotoxin	A0EX09	Staphylococcus_phage	6.4e-23	32.3
AVG66728.1\|1496774_1497503_-	exotoxin	A0EX09	Staphylococcus_phage	2.3e-28	34.9
AVG66729.1\|1497698_1498469_-	transcriptional regulator	A0A1P8L6G7	Staphylococcus_phage	6.2e-141	100.0
AVG66730.1\|1498627_1498852_+	DUF739 domain-containing protein	A7TW90	Staphylococcus_phage	4.5e-36	100.0
AVG66731.1\|1498869_1499130_+	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
AVG66732.1\|1499153_1499693_-	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
AVG66733.1\|1500510_1500708_+	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
AVG66734.1\|1500738_1500879_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
AVG66735.1\|1500893_1501526_-	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
AVG66736.1\|1501584_1501905_+	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
AVG66737.1\|1501901_1502063_+	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
AVG66738.1\|1502155_1502416_+	hypothetical protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
AVG66739.1\|1502424_1502688_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AVG68042.1\|1502696_1504640_+	ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	99.1
AVG66740.1\|1504641_1505562_+	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
AVG66741.1\|1505642_1506260_+	MBL fold metallo-hydrolase	A0A1W6JPL3	Staphylococcus_phage	1.3e-85	98.1
AVG66742.1\|1506260_1506731_+	Single-stranded DNA-binding protein 1	A0A1P8L6D9	Staphylococcus_phage	7.7e-78	96.2
AVG66743.1\|1506760_1507654_+	DnaD domain protein	A0A0E3TAG7	Staphylococcus_phage	1.6e-137	97.6
AVG66744.1\|1507660_1507879_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	4.0e-37	98.6
AVG66745.1\|1507887_1508292_+	RusA family crossover junction endodeoxyribonuclease	A0A0H3U2W2	Staphylococcus_phage	6.9e-67	91.0
AVG66746.1\|1508632_1508782_+	transcriptional regulator	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AVG66747.1\|1508940_1509591_+	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
AVG66748.1\|1509590_1509791_+	hypothetical protein	A0A2I6PDV9	Staphylococcus_phage	4.0e-28	98.5
AVG66749.1\|1509694_1509907_-	hypothetical protein	NA	NA	NA	NA
AVG66750.1\|1509813_1510284_+	hypothetical protein	D2JLE0	Staphylococcus_phage	1.7e-69	99.3
AVG66751.1\|1510398_1510851_+	hypothetical protein	D2JLE1	Staphylococcus_phage	1.4e-79	100.0
AVG68043.1\|1510866_1511211_+	HNH endonuclease	D2JLE2	Staphylococcus_phage	4.2e-65	100.0
AVG66752.1\|1511339_1511807_+\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	1.1e-81	100.0
AVG66753.1\|1511809_1513504_+\|terminase	phage terminase large subunit	D2JLE4	Staphylococcus_phage	0.0e+00	100.0
AVG66754.1\|1513478_1513718_+	hypothetical protein	A7TWC1	Staphylococcus_phage	1.2e-34	98.7
AVG68044.1\|1513783_1514974_+\|portal	phage portal protein	D2JLE6	Staphylococcus_phage	1.8e-224	100.0
AVG66755.1\|1514966_1515551_+\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	9.8e-107	100.0
AVG66756.1\|1515638_1516886_+\|capsid	phage major capsid protein	A7TWC4	Staphylococcus_phage	5.0e-209	100.0
AVG66757.1\|1516921_1517080_+	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
AVG66758.1\|1517088_1517421_+\|head,tail	phage head-tail adapter protein	D2JLF0	Staphylococcus_phage	2.1e-58	100.0
AVG66759.1\|1517407_1517743_+\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
AVG66760.1\|1517742_1518120_+	hypothetical protein	D2JLF2	Staphylococcus_phage	1.1e-61	100.0
AVG66761.1\|1518116_1518497_+	hypothetical protein	D2JLF3	Staphylococcus_phage	2.2e-67	99.2
AVG66762.1\|1518497_1519451_+\|tail	phage tail protein	A7TWD0	Staphylococcus_phage	6.2e-175	100.0
AVG66763.1\|1519515_1519962_+	hypothetical protein	D2JLF5	Staphylococcus_phage	5.4e-73	100.0
AVG66764.1\|1520021_1520144_+	hypothetical protein	D2JLF6	Staphylococcus_phage	6.9e-15	100.0
AVG66765.1\|1520199_1524849_+\|tail	phage tail tape measure protein	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	94.7
AVG66766.1\|1524848_1526339_+\|tail	phage tail protein	R9QST9	Staphylococcus_phage	3.1e-298	100.0
AVG66767.1\|1526354_1530137_+	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.4
AVG66768.1\|1530129_1530282_+	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
1530234:1530251	attR	NA	NA	NA	NA
AVG66769.1\|1530327_1530615_+	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
AVG66770.1\|1530670_1531045_+	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
AVG66771.1\|1531417_1532191_+	enterotoxin	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
AVG68045.1\|1532299_1532476_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
AVG66772.1\|1532528_1532636_-	hypothetical protein	NA	NA	NA	NA
AVG66773.1\|1532687_1532942_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AVG66774.1\|1532953_1533709_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	7.6e-152	99.6
AVG66775.1\|1533899_1534391_+	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
AVG66776.1\|1534837_1534993_-	amidase	NA	NA	NA	NA
AVG66777.1\|1534919_1535174_+	amidase	Q4ZCK0	Staphylococcus_virus	8.0e-13	93.0
AVG66778.1\|1535080_1535377_+	peptidoglycan hydrolase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
AVG66779.1\|1535888_1536239_+	inhibitor	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
AVG66780.1\|1536291_1536552_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
AVG66781.1\|1536530_1536839_-	hypothetical protein	M9NTD8	Staphylococcus_phage	3.2e-40	100.0
AVG66782.1\|1536862_1537042_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
AVG66783.1\|1537413_1537614_-	hypothetical protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0

DBSCAN-SWA_3

1630929 : 1736795

104

Staphylococcus_phage(93.22%)

protease,bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG66868.1\|1630929_1632072_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
AVG66869.1\|1632076_1632547_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AVG66870.1\|1632705_1633305_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
AVG66871.1\|1633329_1633482_+	hypothetical protein	NA	NA	NA	NA
AVG66872.1\|1633546_1633810_-	hypothetical protein	NA	NA	NA	NA
AVG66873.1\|1634087_1634483_+	hypothetical protein	NA	NA	NA	NA
AVG66874.1\|1634678_1636064_+	class II fumarate hydratase	NA	NA	NA	NA
AVG66875.1\|1636524_1637346_-	RluA family pseudouridine synthase	NA	NA	NA	NA
AVG66876.1\|1637508_1638621_+	histidine kinase	NA	NA	NA	NA
AVG66877.1\|1638642_1639266_+	DNA-binding response regulator	NA	NA	NA	NA
AVG66878.1\|1639621_1640086_+	transcriptional regulator	NA	NA	NA	NA
AVG66879.1\|1640264_1641389_+	DUF445 domain-containing protein	NA	NA	NA	NA
AVG66880.1\|1641457_1641802_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
AVG66881.1\|1642074_1642281_-	hypothetical protein	NA	NA	NA	NA
AVG66882.1\|1642294_1642393_+	hypothetical protein	NA	NA	NA	NA
AVG66883.1\|1642683_1643880_+	exonuclease SbcCD subunit D	NA	NA	NA	NA
AVG66884.1\|1643869_1646806_+	DNA repair protein Rad50	NA	NA	NA	NA
AVG66885.1\|1646802_1647744_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
AVG66886.1\|1647864_1648827_-	foldase	NA	NA	NA	NA
AVG66887.1\|1649031_1649589_-	DUF3267 domain-containing protein	NA	NA	NA	NA
AVG66888.1\|1650137_1650344_-	hypothetical protein	NA	NA	NA	NA
AVG66889.1\|1650321_1650687_-	YtxH domain-containing protein	NA	NA	NA	NA
AVG66890.1\|1650828_1651251_-	HIT family protein	NA	NA	NA	NA
AVG66891.1\|1651384_1652125_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.0e-25	30.3
AVG66892.1\|1652117_1653341_+	multidrug ABC transporter ATP-binding protein	NA	NA	NA	NA
AVG66893.1\|1653464_1653968_-	signal transduction protein TRAP	NA	NA	NA	NA
AVG66894.1\|1654130_1654241_+	hypothetical protein	NA	NA	NA	NA
AVG66895.1\|1654230_1655268_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
AVG66896.1\|1655325_1656249_+	ferrochelatase	NA	NA	NA	NA
AVG66897.1\|1656272_1657673_+	protoporphyrinogen oxidase	NA	NA	NA	NA
AVG66898.1\|1657613_1657901_-	hypothetical protein	NA	NA	NA	NA
AVG66899.1\|1657994_1658549_+	serine hydrolase family protein	NA	NA	NA	NA
AVG66900.1\|1661005_1661794_-	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8
AVG66901.1\|1661806_1662262_-	hypothetical protein	Q4ZCB9	Staphylococcus_virus	6.3e-61	76.2
AVG66902.1\|1663158_1664094_+	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
AVG66903.1\|1664095_1665079_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
AVG66904.1\|1665320_1665464_+	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
AVG66905.1\|1665565_1665757_-	hypothetical protein	NA	NA	NA	NA
AVG66906.1\|1666200_1666344_+	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
AVG66907.1\|1666408_1669402_+\|bacteriocin	bacteriocin biosynthesis protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.0
AVG66908.1\|1669394_1670639_+	lanthionine synthetase	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
AVG66909.1\|1670654_1671173_+	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
AVG66910.1\|1671182_1672556_+	peptidase S8	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
AVG66911.1\|1672578_1673271_+	lantibiotic ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
AVG66912.1\|1673267_1674029_+	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
AVG66913.1\|1674025_1674724_+	BsaG protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
AVG66914.1\|1675197_1675764_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	4.3e-99	99.5
AVG66915.1\|1676073_1676292_+	hypothetical protein	NA	NA	NA	NA
AVG66916.1\|1676727_1677435_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
AVG66917.1\|1677559_1678282_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
AVG66918.1\|1678339_1679059_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	3.2e-131	99.6
AVG66919.1\|1679179_1679899_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	9.2e-131	99.2
AVG66920.1\|1679963_1680098_+	hypothetical protein	NA	NA	NA	NA
AVG66921.1\|1680078_1681818_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
AVG66922.1\|1681810_1683010_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.0e-227	99.5
AVG66923.1\|1689216_1689318_-	hypothetical protein	NA	NA	NA	NA
AVG66924.1\|1689738_1689882_+	hypothetical protein	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
AVG66925.1\|1690084_1690294_+\|transposase	transposase	A0A2H4PQV6	Staphylococcus_phage	1.4e-31	100.0
AVG66926.1\|1690485_1690869_+	hypothetical protein	NA	NA	NA	NA
AVG66927.1\|1690879_1691056_+	hypothetical protein	NA	NA	NA	NA
AVG66928.1\|1691429_1691897_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	3.3e-65	100.0
AVG66929.1\|1692184_1692757_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.3e-22	89.7
AVG66930.1\|1692857_1693199_-	DUF3969 domain-containing protein	A0A2H4PQN6	Staphylococcus_phage	8.1e-53	92.0
AVG66931.1\|1693239_1693866_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.6e-91	94.7
AVG66932.1\|1693939_1694935_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.2e-73	97.2
AVG66933.1\|1695015_1695666_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	3.0e-56	99.1
AVG68051.1\|1695968_1696424_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.3
AVG66934.1\|1696582_1698061_+	2-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.6e-281	97.0
AVG66935.1\|1698065_1699067_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
AVG66936.1\|1699063_1699321_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AVG66937.1\|1699386_1699860_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
AVG68052.1\|1699864_1700611_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
AVG66938.1\|1700988_1702581_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AVG66939.1\|1702952_1704146_+	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AVG66940.1\|1704270_1705179_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.7e-137	99.0
AVG66941.1\|1705390_1706224_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
AVG66942.1\|1706235_1706415_-	hypothetical protein	NA	NA	NA	NA
AVG66943.1\|1706606_1706960_-	camphor resistance protein CrcB	A0A2H4PQQ7	Staphylococcus_phage	2.0e-22	98.3
AVG66944.1\|1706956_1707322_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AVG66945.1\|1707577_1707880_-	hypothetical protein	NA	NA	NA	NA
AVG66946.1\|1708139_1708853_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AVG66947.1\|1710222_1710666_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AVG66948.1\|1710652_1711096_-	competence protein ComK	NA	NA	NA	NA
AVG66949.1\|1711208_1711679_-	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AVG66950.1\|1711877_1712102_+	hypothetical protein	NA	NA	NA	NA
AVG66951.1\|1712377_1713232_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AVG66952.1\|1713318_1714611_-	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	3.2e-227	99.5
AVG66953.1\|1714610_1714925_-	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
AVG66954.1\|1715447_1716950_+	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.5e-29	98.6
AVG66955.1\|1717442_1718474_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.6e-197	99.7
AVG66956.1\|1718480_1719113_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
AVG66957.1\|1719123_1720305_+	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
AVG66958.1\|1720317_1720782_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
AVG66959.1\|1720903_1721905_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
AVG68053.1\|1721813_1722005_+	hypothetical protein	NA	NA	NA	NA
AVG66960.1\|1722016_1722136_+	hypothetical protein	NA	NA	NA	NA
AVG66961.1\|1722138_1722966_+	alpha/beta hydrolase	NA	NA	NA	NA
AVG66962.1\|1723539_1723941_+	MarR family transcriptional regulator	NA	NA	NA	NA
AVG66963.1\|1724060_1724624_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AVG66964.1\|1724620_1725574_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AVG66965.1\|1725683_1726865_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	6.2e-217	99.7
AVG66966.1\|1727152_1729576_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.7
AVG66967.1\|1729597_1729909_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
AVG66968.1\|1730234_1736795_+	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	5.9e-301	96.8

DBSCAN-SWA_4

1860467 : 1869510

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG67082.1\|1860467_1861472_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
AVG67083.1\|1861473_1862499_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AVG67084.1\|1862521_1863661_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AVG67085.1\|1863679_1863940_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AVG67086.1\|1864214_1866494_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AVG67087.1\|1866696_1868970_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.8e-63	29.1
AVG67088.1\|1868991_1869510_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_5

2482450 : 2490923

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG67660.1\|2482450_2483017_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-28	40.1
AVG67661.1\|2483019_2484048_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
AVG67662.1\|2484040_2485525_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
AVG67663.1\|2485503_2487693_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
AVG67664.1\|2487685_2488357_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVG67665.1\|2488358_2488622_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVG67666.1\|2488621_2489326_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AVG67667.1\|2489329_2490454_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AVG67668.1\|2490440_2490923_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_6

2509777 : 2528810

Staphylococcus_phage(33.33%)

bacteriocin,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG67684.1\|2509777_2510779_+\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	6.2e-16	32.3
AVG67685.1\|2510860_2512042_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
AVG67686.1\|2512079_2512409_+	staphostatin B	NA	NA	NA	NA
AVG67687.1\|2512646_2513468_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AVG67688.1\|2513460_2514264_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AVG67689.1\|2514250_2515924_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase	NA	NA	NA	NA
AVG67690.1\|2515910_2517122_-	isochorismate synthase	NA	NA	NA	NA
AVG67691.1\|2517198_2517303_-	hypothetical protein	NA	NA	NA	NA
AVG67692.1\|2517453_2518392_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
AVG67693.1\|2518442_2518994_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVG67694.1\|2519083_2519374_+	NINE protein	A0A060AN66	Enterococcus_phage	4.4e-07	39.2
AVG67695.1\|2519437_2519569_+	hypothetical protein	NA	NA	NA	NA
AVG67696.1\|2519614_2520574_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVG67697.1\|2521061_2521418_+	DoxX family protein	NA	NA	NA	NA
AVG67698.1\|2521506_2522988_-	glycosyl transferase family 1	NA	NA	NA	NA
AVG67699.1\|2522993_2523281_-	hypothetical protein	NA	NA	NA	NA
AVG67700.1\|2523621_2523912_+	hypothetical protein	NA	NA	NA	NA
AVG67701.1\|2523999_2524641_-\|bacteriocin	bacteriocin ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-19	33.7
AVG67702.1\|2524637_2524958_-	hypothetical protein	NA	NA	NA	NA
AVG68078.1\|2526967_2527240_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AVG67703.1\|2527249_2527351_-	hypothetical protein	NA	NA	NA	NA
AVG68079.1\|2527889_2527967_-\|holin	putative holin-like toxin	NA	NA	NA	NA
AVG67704.1\|2528207_2528810_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

2534775 : 2584740

Staphylococcus_phage(83.33%)

tail,terminase,portal,protease,holin,head,integrase,capsid

attL 2537115:2537141|attR 2581869:2581895

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG67711.1\|2534775_2537100_-	PDZ domain-containing protein	W5SAB9	Pithovirus	2.8e-11	27.4
2537115:2537141	attL	NA	NA	NA	NA
AVG67712.1\|2537660_2539115_-	CHAP domain-containing protein	I1W626	Staphylococcus_phage	1.2e-286	98.8
AVG67713.1\|2539125_2539428_-\|holin	phage holin	B7T0L0	Staphylococcus_virus	4.1e-48	100.0
AVG67714.1\|2539563_2539863_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
AVG67715.1\|2539908_2540073_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AVG67716.1\|2540065_2540455_-	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AVG67717.1\|2540454_2541921_-	DUF2479 domain-containing protein	A0A2I6PDE3	Staphylococcus_phage	9.3e-271	98.2
AVG67718.1\|2541920_2543831_-	hypothetical protein	A0A2K9VBU3	Staphylococcus_phage	0.0e+00	100.0
AVG67719.1\|2543846_2544137_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
AVG67720.1\|2544136_2545720_-	peptidase	Q4ZD01	Staphylococcus_virus	1.3e-305	98.7
AVG67721.1\|2545728_2546553_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
AVG67722.1\|2546552_2552753_-\|tail	phage tail tape measure protein	A0A2K9VBQ5	Staphylococcus_phage	0.0e+00	99.7
AVG67723.1\|2552766_2552925_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AVG67724.1\|2552966_2553317_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
AVG67725.1\|2553374_2553830_-\|tail	phage tail protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
AVG67726.1\|2553921_2554563_-\|tail	phage tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AVG67727.1\|2554597_2554993_-	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
AVG67728.1\|2554993_2555395_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
AVG67729.1\|2555391_2555724_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
AVG67730.1\|2555735_2556014_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AVG67731.1\|2556082_2557246_-\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
AVG67732.1\|2557257_2558031_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
AVG67733.1\|2558014_2559253_-\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	1.2e-234	99.8
AVG67734.1\|2559257_2560949_-\|terminase	terminase large subunit	A0A2I6PE99	Staphylococcus_phage	0.0e+00	99.6
AVG67735.1\|2560938_2561244_-\|terminase	phage terminase small subunit P27 family	U5U414	Staphylococcus_phage	2.9e-49	100.0
AVG67736.1\|2561369_2561690_-	HNH endonuclease	A0A2K9VBV6	Staphylococcus_phage	4.6e-50	86.8
AVG67737.1\|2561850_2562288_-	transcriptional regulator	Q4ZCF5	Staphylococcus_virus	3.6e-77	99.3
AVG67738.1\|2562300_2563677_-	ATP-dependent helicase	A0A2I6PE95	Staphylococcus_phage	7.4e-262	99.3
AVG67739.1\|2563657_2563948_-	VRR-NUC domain-containing protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
AVG67740.1\|2564081_2564186_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
AVG67741.1\|2564288_2566736_-	hypothetical protein	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	99.0
AVG67742.1\|2566790_2566997_+	hypothetical protein	A0A1X9IGZ9	Staphylococcus_phage	7.6e-30	100.0
AVG67743.1\|2567023_2567224_-	DUF1514 domain-containing protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
AVG67744.1\|2567291_2567444_-	transcriptional regulator	A0A2I6PEM5	Staphylococcus_phage	2.0e-19	100.0
AVG67745.1\|2567491_2568016_-	hypothetical protein	A0A0K1LKF9	Staphylococcus_phage	4.7e-84	88.5
AVG67746.1\|2568015_2568210_-	DUF1381 domain-containing protein	A1KX86	Staphylococcus_virus	7.9e-21	84.4
AVG67747.1\|2568226_2568400_-	hypothetical protein	A0A2I6PEA8	Staphylococcus_phage	3.6e-25	100.0
AVG67748.1\|2568436_2568973_-	dUTPase	A0A1P8L6E0	Staphylococcus_phage	1.4e-94	99.4
AVG67749.1\|2568965_2569214_-	DUF1024 domain-containing protein	C8CH04	Staphylococcus_phage	5.9e-37	96.3
AVG67750.1\|2569206_2569515_-	hypothetical protein	Q4ZBK6	Staphylococcus_phage	9.9e-50	97.1
AVG67751.1\|2569511_2569859_-	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
AVG67752.1\|2569855_2570260_-	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	4.2e-72	100.0
AVG67753.1\|2570262_2570469_-	hypothetical protein	A0A2K9VBT9	Staphylococcus_phage	3.0e-34	100.0
AVG67754.1\|2570482_2570731_-	hypothetical protein	Q8SDR2	Staphylococcus_virus	1.8e-38	93.9
AVG67755.1\|2570730_2570985_-	DUF3310 domain-containing protein	A0A059T7J9	Staphylococcus_phage	2.8e-42	100.0
AVG67756.1\|2570984_2571386_-	PVL family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
AVG67757.1\|2571385_2571571_-	DUF3113 domain-containing protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
AVG68080.1\|2571583_2573536_-	DNA polymerase	B7T0G8	Staphylococcus_virus	0.0e+00	98.9
AVG67758.1\|2573604_2574162_-	DUF2815 domain-containing protein	A0A2K9VBT2	Staphylococcus_phage	1.3e-92	95.7
AVG67759.1\|2574187_2575354_-	DUF2800 domain-containing protein	A0A0K1LKE3	Staphylococcus_phage	4.5e-220	99.5
AVG67760.1\|2575350_2575713_-	hypothetical protein	A0A0K1LKE9	Staphylococcus_phage	1.7e-53	95.8
AVG67761.1\|2575726_2575987_-	DUF1108 domain-containing protein	A0EWW8	Staphylococcus_phage	8.4e-42	94.2
AVG67762.1\|2576026_2576287_-	hypothetical protein	A0A0H3U2W4	Staphylococcus_phage	1.3e-39	98.8
AVG67763.1\|2576379_2576541_-	DUF1270 domain-containing protein	A0A059T7J6	Staphylococcus_phage	3.6e-19	94.3
AVG67764.1\|2576552_2576816_-	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
AVG67765.1\|2576840_2577056_-	hypothetical protein	A0A2I6PEK7	Staphylococcus_phage	1.0e-32	100.0
AVG67766.1\|2577102_2577342_+	hypothetical protein	A0A2I6PE22	Staphylococcus_phage	6.7e-38	100.0
AVG67767.1\|2577598_2577790_-	XRE family transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
AVG67768.1\|2577950_2578280_+	XRE family transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
AVG67769.1\|2578292_2578754_+	toxin	A0A2I6PEK4	Staphylococcus_phage	4.9e-85	98.0
AVG67770.1\|2578771_2579206_+	hypothetical protein	A0A2I6PEM0	Staphylococcus_phage	7.5e-19	93.1
AVG67771.1\|2579234_2579630_+	hypothetical protein	I1W601	Staphylococcus_phage	3.2e-69	99.2
AVG67772.1\|2579828_2580452_-	hypothetical protein	B7T0F3	Staphylococcus_virus	1.3e-104	99.5
AVG67773.1\|2580578_2581784_+\|integrase	site-specific integrase	B7T0F2	Staphylococcus_virus	4.2e-221	100.0
AVG67774.1\|2582072_2582876_-	hypothetical protein	S5MAL1	Bacillus_phage	4.2e-31	41.0
2581869:2581895	attR	NA	NA	NA	NA
AVG67775.1\|2583177_2584740_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	2.2e-36	28.2

DBSCAN-SWA_8

2779027 : 2793758

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG67965.1\|2779027_2779789_-	iron ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6
AVG67966.1\|2779785_2780742_-	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AVG68085.1\|2780728_2781700_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AVG67967.1\|2781738_2781894_-	hypothetical protein	NA	NA	NA	NA
AVG67968.1\|2782170_2782275_-	hypothetical protein	NA	NA	NA	NA
AVG67969.1\|2782407_2783379_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AVG67970.1\|2783496_2785602_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AVG67971.1\|2785564_2785963_-	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AVG67972.1\|2786112_2786379_-	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
AVG67973.1\|2786763_2787630_+	EamA/RhaT family transporter	NA	NA	NA	NA
AVG67974.1\|2787649_2788150_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AVG67975.1\|2788179_2788425_+	hypothetical protein	NA	NA	NA	NA
AVG67976.1\|2788490_2789996_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AVG67977.1\|2790073_2790175_-	hypothetical protein	NA	NA	NA	NA
AVG67978.1\|2790264_2791182_+	lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
AVG67979.1\|2791594_2791690_-	hypothetical protein	NA	NA	NA	NA
AVG67980.1\|2791862_2792405_-	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AVG67981.1\|2792699_2793758_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.7

Anti-CRISPR protein detection

Acr_ID: CP026964.1|AVG67977.1|2790073_2790175_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP026964.1|AVG67977.1|2790073_2790175_-|hypothetical-protein

2790073_2790175_-

33 aa aa

2779027-2793758

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP026964_2	Orphan	2.2\|806524\|16\|CP026964\|PILER-CR	806524-806539	16	2782156-2782141	1
CP026964_9	Unclear	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	2782105-2782130	2
CP026964_9	Unclear	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	2782161-2782186	2
CP026964_9	Unclear	9.1\|2307856\|26\|CP026964\|CRISPRCasFinder	2307856-2307881	26	2782217-2782242	2

1. spacer 2.2|806524|16|CP026964|PILER-CR matches to CP026964 position: 2782156-2782141, mismatch: 1

tcagcttacaataatg	CRISPR spacer
tcagctaacaataatg	Protospacer
****** *********

2. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to CP026964 position: 2782105-2782130, mismatch: 2

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttttatgttggggccccg	Protospacer
***** ****.***************

3. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to CP026964 position: 2782161-2782186, mismatch: 2

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtctgcttctatgttggggccccg	Protospacer
***.* ********************

4. spacer 9.1|2307856|26|CP026964|CRISPRCasFinder matches to CP026964 position: 2782217-2782242, mismatch: 2

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ******.*************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026964

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information