CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP026962	Staphylococcus aureus strain FDAARGOS_6 chromosome, complete genome	10 crisprs	cas3,DEDDh,DinG,csa3,WYL	10	3	7	0
CP026963	Staphylococcus aureus strain FDAARGOS_6 plasmid unnamed1	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP026962_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_1

521348-521448

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026962_1

>merge|CP026962|1|521348-521448|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>CP026962|1|1|521348-521448|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG63113.1\|517202_517772_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP026962.1\|AVG63110.1\|514592_515219_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
CP026962.1\|AVG63108.1\|513307_513889_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP026962.1\|AVG63121.1\|524263_524842_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP026962.1\|AVG63123.1\|526147_527614_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP026962.1\|AVG63111.1\|515291_515585_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63112.1\|515663_517187_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP026962.1\|AVG63118.1\|521464_522421_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
CP026962.1\|AVG63115.1\|519099_520488_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
CP026962.1\|AVG63127.1\|531324_531597_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225511
CP026962.1\|AVG63122.1\|524841_526110_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
CP026962.1\|AVG63119.1\|522538_523201_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63116.1\|520572_520674_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63120.1\|523343_523751_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP026962.1\|AVG63124.1\|527638_529180_+\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
CP026962.1\|AVG63126.1\|530221_530926_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
CP026962.1\|AVG63114.1\|518263_519019_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP026962.1\|AVG63117.1\|520881_521139_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63109.1\|513954_514338_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63125.1\|529292_529829_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG63113.1\|517202_517772_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP026962.1\|AVG63110.1\|514592_515219_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
CP026962.1\|AVG63108.1\|513307_513889_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
CP026962.1\|AVG63121.1\|524263_524842_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP026962.1\|AVG63123.1\|526147_527614_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP026962.1\|AVG63118.1\|521464_522421_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
CP026962.1\|AVG63112.1\|515663_517187_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP026962.1\|AVG63124.1\|527638_529180_+\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP026962.1\|AVG63115.1\|519099_520488_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP026962.1\|AVG63127.1\|531324_531597_-\|hypothetical-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
CP026962.1\|AVG63122.1\|524841_526110_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
CP026962.1\|AVG63126.1\|530221_530926_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
CP026962.1\|AVG63120.1\|523343_523751_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
CP026962.1\|AVG63114.1\|518263_519019_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88

>CP026962.1|AVG63117.1|520881_521139_-|hypothetical-protein
MLVTDESHKCTLIFTFTTNAFLLKQKYLFTVAFELPPAHTNTQKMLILIRQNFLQRVCSKRLFKVDHLLSFHSINMRLAIFIKPP
>CP026962.1|AVG63116.1|520572_520674_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>CP026962.1|AVG63115.1|519099_520488_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>CP026962.1|AVG63114.1|518263_519019_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP026962.1|AVG63113.1|517202_517772_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP026962.1|AVG63112.1|515663_517187_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP026962.1|AVG63111.1|515291_515585_-|hypothetical-protein
MINLIYTTRCAIMLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP026962.1|AVG63110.1|514592_515219_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP026962.1|AVG63109.1|513954_514338_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>CP026962.1|AVG63108.1|513307_513889_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>CP026962.1|AVG63118.1|521464_522421_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP026962.1|AVG63119.1|522538_523201_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP026962.1|AVG63120.1|523343_523751_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>CP026962.1|AVG63121.1|524263_524842_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP026962.1|AVG63122.1|524841_526110_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP026962.1|AVG63123.1|526147_527614_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP026962.1|AVG63124.1|527638_529180_+|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP026962.1|AVG63125.1|529292_529829_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>CP026962.1|AVG63126.1|530221_530926_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>CP026962.1|AVG63127.1|531324_531597_-|hypothetical-protein
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Crispr_ID: CP026962_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_2

756636-756728

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026962_2

>merge|CP026962|2|756636-756728|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>CP026962|2|2|756636-756728|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG65222.1\|756856_757684_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
CP026962.1\|AVG65220.1\|751014_751536_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
CP026962.1\|AVG63326.1\|753732_755394_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP026962.1\|AVG63335.1\|764389_765319_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225778
CP026962.1\|AVG63327.1\|755338_755647_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63329.1\|758836_759556_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
CP026962.1\|AVG65223.1\|757831_758782_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
CP026962.1\|AVG63322.1\|749175_749652_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026962.1\|AVG63331.1\|760475_760982_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG65221.1\|753352_753736_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
CP026962.1\|AVG63324.1\|752034_753045_+\|zinc-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP026962.1\|AVG63321.1\|748470_749007_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
CP026962.1\|AVG63328.1\|755782_756418_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
CP026962.1\|AVG63332.1\|761143_761860_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63330.1\|759539_760340_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP026962.1\|AVG63325.1\|753119_753227_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63333.1\|762028_762817_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP026962.1\|AVG63334.1\|763067_763442_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
CP026962.1\|AVG63336.1\|765513_765738_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
CP026962.1\|AVG63323.1\|749691_750987_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG65222.1\|756856_757684_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.32108e-72
CP026962.1\|AVG65220.1\|751014_751536_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
CP026962.1\|AVG63326.1\|753732_755394_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP026962.1\|AVG63335.1\|764389_765319_-\|hypothetical-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
CP026962.1\|AVG63329.1\|758836_759556_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
CP026962.1\|AVG65223.1\|757831_758782_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
CP026962.1\|AVG63322.1\|749175_749652_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP026962.1\|AVG65221.1\|753352_753736_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
CP026962.1\|AVG63324.1\|752034_753045_+\|zinc-dependent-alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP026962.1\|AVG63321.1\|748470_749007_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
CP026962.1\|AVG63328.1\|755782_756418_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
CP026962.1\|AVG63330.1\|759539_760340_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
CP026962.1\|AVG63333.1\|762028_762817_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
CP026962.1\|AVG63334.1\|763067_763442_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP026962.1\|AVG63336.1\|765513_765738_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
CP026962.1\|AVG63323.1\|749691_750987_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150

>CP026962.1|AVG63328.1|755782_756418_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>CP026962.1|AVG63327.1|755338_755647_-|hypothetical-protein
MTRIEKSLLQANFRSVNYCHYNFVEHRTLIYVSGSLMQLCRASNCVPLNLIHILSIPQYVTYLKKTLQHKVSFEKLYVGVYINVLTLIQVRLHRPLPMHFSM
>CP026962.1|AVG63326.1|753732_755394_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP026962.1|AVG65221.1|753352_753736_+|DUF1934-domain-containing-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP026962.1|AVG63325.1|753119_753227_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>CP026962.1|AVG63324.1|752034_753045_+|zinc-dependent-alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP026962.1|AVG65220.1|751014_751536_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP026962.1|AVG63323.1|749691_750987_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP026962.1|AVG63322.1|749175_749652_+|N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP026962.1|AVG63321.1|748470_749007_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP026962.1|AVG65222.1|756856_757684_+|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP026962.1|AVG65223.1|757831_758782_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP026962.1|AVG63329.1|758836_759556_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>CP026962.1|AVG63330.1|759539_760340_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>CP026962.1|AVG63331.1|760475_760982_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP026962.1|AVG63332.1|761143_761860_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>CP026962.1|AVG63333.1|762028_762817_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>CP026962.1|AVG63334.1|763067_763442_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP026962.1|AVG63335.1|764389_765319_-|hypothetical-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>CP026962.1|AVG63336.1|765513_765738_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: CP026962_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_3

819896-819994

Orphan

Consensus_repeat	Method
AAGAGCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026962_3

>merge|CP026962|3|819896-819994|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGGACAAAGGAATACAGTTGGTTGCTAATGCACCAACTGCATAAGAGCCCCTAATTAATAAATTAAAAGGGG

>CP026962|3|3|819896-819994|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGG	ACAAAGGAATACAGTTGGTTGCTAATGCACCAACTGCAT
AAGAGCCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG63396.1\|824053_824596_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
CP026962.1\|AVG63389.1\|818944_819811_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
CP026962.1\|AVG63391.1\|821228_821717_+\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
CP026962.1\|AVG63397.1\|824691_825258_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
CP026962.1\|AVG63398.1\|825259_825718_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
CP026962.1\|AVG65224.1\|816093_816453_+\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
CP026962.1\|AVG63395.1\|823674_823974_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63394.1\|823141_823537_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240271
CP026962.1\|AVG63385.1\|816642_817359_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
CP026962.1\|AVG63381.1\|809703_810711_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
CP026962.1\|AVG63386.1\|817358_817832_+\|cupin	unknown	unknown	gnl\|CDD\|226072
CP026962.1\|AVG63392.1\|821815_822505_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63393.1\|822631_823075_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP026962.1\|AVG63383.1\|812456_813101_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223742
CP026962.1\|AVG63399.1\|825720_826404_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
CP026962.1\|AVG63384.1\|813797_815948_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
CP026962.1\|AVG63390.1\|820011_821232_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341024
CP026962.1\|AVG63388.1\|818184_818829_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
CP026962.1\|AVG63382.1\|811298_812096_-\|peptidase-M23	unknown	unknown	gnl\|CDD\|226451
CP026962.1\|AVG63387.1\|817923_818040_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG63396.1\|824053_824596_+\|N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.77698e-28
CP026962.1\|AVG63389.1\|818944_819811_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.51151e-39
CP026962.1\|AVG63391.1\|821228_821717_+\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
CP026962.1\|AVG63397.1\|824691_825258_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.24037e-61
CP026962.1\|AVG65224.1\|816093_816453_+\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.54609e-22
CP026962.1\|AVG63398.1\|825259_825718_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.18273e-77
CP026962.1\|AVG63394.1\|823141_823537_+\|hypothetical-protein	gnl\|CDD\|240271	PTZ00108, PTZ00108, DNA topoisomerase 2-like protein; Provisional.	0.00179936
CP026962.1\|AVG63385.1\|816642_817359_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
CP026962.1\|AVG63381.1\|809703_810711_+\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	5.23541e-104
CP026962.1\|AVG63386.1\|817358_817832_+\|cupin	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	1.99109e-74
CP026962.1\|AVG63393.1\|822631_823075_+\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.56694e-12
CP026962.1\|AVG63383.1\|812456_813101_+\|hypothetical-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	1.16188e-32
CP026962.1\|AVG63399.1\|825720_826404_-\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000491798
CP026962.1\|AVG63384.1\|813797_815948_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.1737e-20
CP026962.1\|AVG63390.1\|820011_821232_+\|MFS-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.37741e-101
CP026962.1\|AVG63388.1\|818184_818829_+\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.46792e-91
CP026962.1\|AVG63382.1\|811298_812096_-\|peptidase-M23	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.27934e-40

>CP026962.1|AVG63389.1|818944_819811_+|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>CP026962.1|AVG63388.1|818184_818829_+|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN
>CP026962.1|AVG63387.1|817923_818040_+|hypothetical-protein
MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN
>CP026962.1|AVG63386.1|817358_817832_+|cupin
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTFSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>CP026962.1|AVG63385.1|816642_817359_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>CP026962.1|AVG65224.1|816093_816453_+|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
>CP026962.1|AVG63384.1|813797_815948_+|AraC-family-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>CP026962.1|AVG63383.1|812456_813101_+|hypothetical-protein
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>CP026962.1|AVG63382.1|811298_812096_-|peptidase-M23
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>CP026962.1|AVG63381.1|809703_810711_+|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLFF
>CP026962.1|AVG63390.1|820011_821232_+|MFS-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>CP026962.1|AVG63391.1|821228_821717_+|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>CP026962.1|AVG63392.1|821815_822505_-|hypothetical-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>CP026962.1|AVG63393.1|822631_823075_+|N-acetyltransferase
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISNTIHKNNLPMISLNKDLGYQVSHVKMYKDID
>CP026962.1|AVG63394.1|823141_823537_+|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKDKEASQDKQSKDQTKSSDKDNHKKPTSADKDQKANDKHQS
>CP026962.1|AVG63395.1|823674_823974_+|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGHTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>CP026962.1|AVG63396.1|824053_824596_+|N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEEHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>CP026962.1|AVG63397.1|824691_825258_-|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>CP026962.1|AVG63398.1|825259_825718_-|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
>CP026962.1|AVG63399.1|825720_826404_-|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA

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Crispr_ID: CP026962_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_4

962125-962206

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026962_4

>merge|CP026962|4|962125-962206|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>CP026962|4|4|962125-962206|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG63528.1\|958117_958834_+\|3-dehydroquinase	unknown	unknown	gnl\|CDD\|184156
CP026962.1\|AVG63537.1\|963141_963438_+\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP026962.1\|AVG63534.1\|961142_962021_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
CP026962.1\|AVG63536.1\|962762_963149_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
CP026962.1\|AVG63538.1\|963687_964713_+\|methionine-import-ATP-binding-protein-MetN-2	unknown	unknown	gnl\|CDD\|224058
CP026962.1\|AVG63527.1\|957547_957970_-\|organic-hydroperoxide-reductase-OsmC/OhrA	unknown	unknown	gnl\|CDD\|274649
CP026962.1\|AVG63532.1\|960583_960964_+\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|234918
CP026962.1\|AVG63531.1\|960069_960426_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
CP026962.1\|AVG63543.1\|968199_968961_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
CP026962.1\|AVG63535.1\|962439_962553_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63539.1\|964705_965401_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
CP026962.1\|AVG63540.1\|965418_966240_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
CP026962.1\|AVG63526.1\|956654_957149_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
CP026962.1\|AVG63541.1\|966593_966788_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
CP026962.1\|AVG63533.1\|961027_961141_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63542.1\|967020_967872_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
CP026962.1\|AVG63544.1\|969058_970366_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
CP026962.1\|AVG63525.1\|955882_956500_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
CP026962.1\|AVG63530.1\|959605_959926_-\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP026962.1\|AVG63529.1\|958916_959456_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG63528.1\|958117_958834_+\|3-dehydroquinase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
CP026962.1\|AVG63537.1\|963141_963438_+\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
CP026962.1\|AVG63534.1\|961142_962021_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
CP026962.1\|AVG63536.1\|962762_963149_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
CP026962.1\|AVG63538.1\|963687_964713_+\|methionine-import-ATP-binding-protein-MetN-2	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
CP026962.1\|AVG63527.1\|957547_957970_-\|organic-hydroperoxide-reductase-OsmC/OhrA	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
CP026962.1\|AVG63532.1\|960583_960964_+\|glycine-cleavage-system-protein-H	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
CP026962.1\|AVG63531.1\|960069_960426_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
CP026962.1\|AVG63543.1\|968199_968961_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
CP026962.1\|AVG63540.1\|965418_966240_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
CP026962.1\|AVG63526.1\|956654_957149_-\|N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
CP026962.1\|AVG63541.1\|966593_966788_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
CP026962.1\|AVG63539.1\|964705_965401_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
CP026962.1\|AVG63542.1\|967020_967872_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
CP026962.1\|AVG63544.1\|969058_970366_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
CP026962.1\|AVG63525.1\|955882_956500_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
CP026962.1\|AVG63530.1\|959605_959926_-\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
CP026962.1\|AVG63529.1\|958916_959456_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49

>CP026962.1|AVG63534.1|961142_962021_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>CP026962.1|AVG63533.1|961027_961141_+|hypothetical-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>CP026962.1|AVG63532.1|960583_960964_+|glycine-cleavage-system-protein-H
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>CP026962.1|AVG63531.1|960069_960426_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>CP026962.1|AVG63530.1|959605_959926_-|thioredoxin
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>CP026962.1|AVG63529.1|958916_959456_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>CP026962.1|AVG63528.1|958117_958834_+|3-dehydroquinase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>CP026962.1|AVG63527.1|957547_957970_-|organic-hydroperoxide-reductase-OsmC/OhrA
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>CP026962.1|AVG63526.1|956654_957149_-|N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>CP026962.1|AVG63525.1|955882_956500_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>CP026962.1|AVG63535.1|962439_962553_+|hypothetical-protein
MLGPRQLAHYCKLTYHQLLCWGPAIIEKFVIGVFSFG
>CP026962.1|AVG63536.1|962762_963149_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>CP026962.1|AVG63537.1|963141_963438_+|thioredoxin
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>CP026962.1|AVG63538.1|963687_964713_+|methionine-import-ATP-binding-protein-MetN-2
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>CP026962.1|AVG63539.1|964705_965401_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>CP026962.1|AVG63540.1|965418_966240_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>CP026962.1|AVG63541.1|966593_966788_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>CP026962.1|AVG63542.1|967020_967872_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>CP026962.1|AVG63543.1|968199_968961_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>CP026962.1|AVG63544.1|969058_970366_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK

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Crispr_ID: CP026962_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_5

1010980-1011262

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of CP026962_5

>merge|CP026962|5|1010980-1011262|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>CP026962|5|1|1010980-1011262|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG63595.1\|1015427_1016759_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP026962.1\|AVG63583.1\|1001698_1002127_-\|Na+/H+-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP026962.1\|AVG63588.1\|1006850_1007978_+\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
CP026962.1\|AVG63601.1\|1026234_1027137_+\|FAA-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP026962.1\|AVG63593.1\|1012502_1013882_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP026962.1\|AVG63598.1\|1018203_1018779_+\|signal-peptidase-IB	unknown	unknown	gnl\|CDD\|274044
CP026962.1\|AVG63587.1\|1006111_1006489_+\|general-stress-protein	unknown	unknown	gnl\|CDD\|224023
CP026962.1\|AVG63586.1\|1005102_1005696_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
CP026962.1\|AVG63585.1\|1004655_1005039_-\|kinase	unknown	unknown	gnl\|CDD\|378054
CP026962.1\|AVG63596.1\|1017083_1017659_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP026962.1\|AVG63594.1\|1013871_1015077_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP026962.1\|AVG63584.1\|1002119_1004525_-\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
CP026962.1\|AVG63597.1\|1017663_1018188_+\|inactive-signal-peptidase-IA	unknown	unknown	gnl\|CDD\|274044
CP026962.1\|AVG65228.1\|1001357_1001687_-\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP026962.1\|AVG63590.1\|1009584_1010829_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP026962.1\|AVG63600.1\|1022415_1026069_+\|ATP-dependent-helicase/nuclease-subunit-A	unknown	unknown	gnl\|CDD\|274299
CP026962.1\|AVG63589.1\|1008285_1009476_+\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP026962.1\|AVG63582.1\|999868_1001365_-\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP026962.1\|AVG63592.1\|1011331_1012261_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
CP026962.1\|AVG63599.1\|1018938_1022415_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	unknown	unknown	gnl\|CDD\|213736

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG63595.1\|1015427_1016759_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP026962.1\|AVG63583.1\|1001698_1002127_-\|Na+/H+-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP026962.1\|AVG63588.1\|1006850_1007978_+\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP026962.1\|AVG63601.1\|1026234_1027137_+\|FAA-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
CP026962.1\|AVG63593.1\|1012502_1013882_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP026962.1\|AVG63598.1\|1018203_1018779_+\|signal-peptidase-IB	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
CP026962.1\|AVG63587.1\|1006111_1006489_+\|general-stress-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP026962.1\|AVG63586.1\|1005102_1005696_+\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP026962.1\|AVG63585.1\|1004655_1005039_-\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
CP026962.1\|AVG63596.1\|1017083_1017659_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP026962.1\|AVG63594.1\|1013871_1015077_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP026962.1\|AVG63584.1\|1002119_1004525_-\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP026962.1\|AVG63597.1\|1017663_1018188_+\|inactive-signal-peptidase-IA	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
CP026962.1\|AVG65228.1\|1001357_1001687_-\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
CP026962.1\|AVG63590.1\|1009584_1010829_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP026962.1\|AVG63600.1\|1022415_1026069_+\|ATP-dependent-helicase/nuclease-subunit-A	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP026962.1\|AVG63589.1\|1008285_1009476_+\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP026962.1\|AVG63582.1\|999868_1001365_-\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP026962.1\|AVG63592.1\|1011331_1012261_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP026962.1\|AVG63599.1\|1018938_1022415_+\|ATP-dependent-helicase/deoxyribonuclease-subunit-B	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0

>CP026962.1|AVG63590.1|1009584_1010829_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP026962.1|AVG63589.1|1008285_1009476_+|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP026962.1|AVG63588.1|1006850_1007978_+|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP026962.1|AVG63587.1|1006111_1006489_+|general-stress-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP026962.1|AVG63586.1|1005102_1005696_+|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP026962.1|AVG63585.1|1004655_1005039_-|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP026962.1|AVG63584.1|1002119_1004525_-|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP026962.1|AVG63583.1|1001698_1002127_-|Na+/H+-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP026962.1|AVG65228.1|1001357_1001687_-|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP026962.1|AVG63582.1|999868_1001365_-|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP026962.1|AVG63592.1|1011331_1012261_-|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP026962.1|AVG63593.1|1012502_1013882_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP026962.1|AVG63594.1|1013871_1015077_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP026962.1|AVG63595.1|1015427_1016759_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWIDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP026962.1|AVG63596.1|1017083_1017659_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP026962.1|AVG63597.1|1017663_1018188_+|inactive-signal-peptidase-IA
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>CP026962.1|AVG63598.1|1018203_1018779_+|signal-peptidase-IB
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP026962.1|AVG63599.1|1018938_1022415_+|ATP-dependent-helicase/deoxyribonuclease-subunit-B
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP026962.1|AVG63600.1|1022415_1026069_+|ATP-dependent-helicase/nuclease-subunit-A
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP026962.1|AVG63601.1|1026234_1027137_+|FAA-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP026962_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_6

1144664-1144751

Orphan

Consensus_repeat	Method
CCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP026962_6

>merge|CP026962|6|1144664-1144751|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGGAAGGAGAGGGATACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>CP026962|6|5|1144664-1144751|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGG	AAGGAGAGGGATACATGCGCCGAGCACATGCATAAAAT
CCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG63716.1\|1147992_1148535_+\|DUF697-domain-containing-protein	unknown	unknown	gnl\|CDD\|368297
CP026962.1\|AVG63712.1\|1144540_1144660_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63703.1\|1133118_1135308_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
CP026962.1\|AVG63709.1\|1141387_1142194_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP026962.1\|AVG63713.1\|1144760_1144895_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63714.1\|1145046_1146342_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63710.1\|1142186_1143587_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
CP026962.1\|AVG63717.1\|1148688_1148955_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
CP026962.1\|AVG63708.1\|1139875_1141123_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
CP026962.1\|AVG63711.1\|1143601_1144177_-\|thiamine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227065
CP026962.1\|AVG63707.1\|1138375_1139854_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
CP026962.1\|AVG63706.1\|1137794_1138361_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
CP026962.1\|AVG63704.1\|1135286_1136771_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
CP026962.1\|AVG63719.1\|1150912_1151146_-\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
CP026962.1\|AVG65231.1\|1146362_1146566_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG63718.1\|1148957_1150676_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
CP026962.1\|AVG63720.1\|1151343_1152705_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
CP026962.1\|AVG63705.1\|1136763_1137792_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
CP026962.1\|AVG63715.1\|1146766_1147939_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
CP026962.1\|AVG63721.1\|1152701_1153721_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG63716.1\|1147992_1148535_+\|DUF697-domain-containing-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00779365
CP026962.1\|AVG63706.1\|1137794_1138361_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	7.23817e-92
CP026962.1\|AVG63703.1\|1133118_1135308_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
CP026962.1\|AVG63709.1\|1141387_1142194_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
CP026962.1\|AVG63705.1\|1136763_1137792_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
CP026962.1\|AVG63710.1\|1142186_1143587_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.67975e-64
CP026962.1\|AVG63717.1\|1148688_1148955_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
CP026962.1\|AVG63708.1\|1139875_1141123_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
CP026962.1\|AVG63711.1\|1143601_1144177_-\|thiamine-ABC-transporter-permease	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
CP026962.1\|AVG63707.1\|1138375_1139854_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
CP026962.1\|AVG63704.1\|1135286_1136771_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
CP026962.1\|AVG63719.1\|1150912_1151146_-\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	5.00495e-16
CP026962.1\|AVG63720.1\|1151343_1152705_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
CP026962.1\|AVG63715.1\|1146766_1147939_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	5.6543e-145
CP026962.1\|AVG63718.1\|1148957_1150676_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
CP026962.1\|AVG63721.1\|1152701_1153721_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76

>CP026962.1|AVG63712.1|1144540_1144660_+|hypothetical-protein
MKRDTYQSYLFNNSEEPVHNGLRIIVYKEEEGYMRRAHA
>CP026962.1|AVG63711.1|1143601_1144177_-|thiamine-ABC-transporter-permease
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>CP026962.1|AVG63710.1|1142186_1143587_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>CP026962.1|AVG63709.1|1141387_1142194_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>CP026962.1|AVG63708.1|1139875_1141123_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYKKVSQIQSDHLFYRHDIANKALQLK
>CP026962.1|AVG63707.1|1138375_1139854_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/inosine-monophosphate-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>CP026962.1|AVG63706.1|1137794_1138361_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>CP026962.1|AVG63705.1|1136763_1137792_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>CP026962.1|AVG63704.1|1135286_1136771_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>CP026962.1|AVG63703.1|1133118_1135308_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>CP026962.1|AVG63713.1|1144760_1144895_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>CP026962.1|AVG63714.1|1145046_1146342_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>CP026962.1|AVG65231.1|1146362_1146566_-|hypothetical-protein
MILQMDNFSTILFALKLCIQFSILNSHHLNQSNLVTKKVLSINFIDLYLSKLEIYLTYSVHIKMFNR
>CP026962.1|AVG63715.1|1146766_1147939_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQQINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSAIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>CP026962.1|AVG63716.1|1147992_1148535_+|DUF697-domain-containing-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISNAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>CP026962.1|AVG63717.1|1148688_1148955_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>CP026962.1|AVG63718.1|1148957_1150676_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>CP026962.1|AVG63719.1|1150912_1151146_-|glutaredoxin-family-protein
MSEIIVYTQNDCPPCTFVKNYLNEHHIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>CP026962.1|AVG63720.1|1151343_1152705_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>CP026962.1|AVG63721.1|1152701_1153721_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS

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Crispr_ID: CP026962_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_7

1881014-1881224

Orphan

Consensus_repeat	Method
CAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGANNN	CRT

3 spacers

The CRISPR arrays of CP026962_7

>merge|CP026962|7|1881014-1881224|CRT
CAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGA

>CP026962|7|2|1881014-1881224|CRT
CAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGA	AGCTGGCCAATAGTCAGCTTT
CAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGA	GAATTTCGAAAAGAAATTCT
ACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGC	TGGCCAATAGTCAGCTTT
CAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG64415.1\|1898293_1898857_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744
CP026962.1\|AVG64414.1\|1897343_1898297_+\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
CP026962.1\|AVG64399.1\|1873115_1873427_-\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
CP026962.1\|AVG64409.1\|1884726_1885995_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519
CP026962.1\|AVG64412.1\|1893347_1895765_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
CP026962.1\|AVG64408.1\|1882658_1884320_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
CP026962.1\|AVG64410.1\|1886111_1892672_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
CP026962.1\|AVG64403.1\|1877061_1877853_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|223584
CP026962.1\|AVG64406.1\|1881527_1881950_-\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
CP026962.1\|AVG64398.1\|1872158_1873016_-\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
CP026962.1\|AVG64405.1\|1879254_1880664_-\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|235988
CP026962.1\|AVG64400.1\|1873491_1874568_-\|M42-family-peptidase	unknown	unknown	gnl\|CDD\|349906
CP026962.1\|AVG64401.1\|1874654_1874966_+\|peptidase	unknown	unknown	gnl\|CDD\|227871
CP026962.1\|AVG64404.1\|1878402_1879251_-\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191
CP026962.1\|AVG64411.1\|1893014_1893326_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
CP026962.1\|AVG64413.1\|1896052_1897234_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
CP026962.1\|AVG65250.1\|1875090_1875933_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293814
CP026962.1\|AVG64397.1\|1871533_1872130_-\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
CP026962.1\|AVG64402.1\|1876402_1877047_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
CP026962.1\|AVG64407.1\|1881966_1882662_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG64415.1\|1898293_1898857_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
CP026962.1\|AVG64414.1\|1897343_1898297_+\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
CP026962.1\|AVG64399.1\|1873115_1873427_-\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24
CP026962.1\|AVG64409.1\|1884726_1885995_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
CP026962.1\|AVG64412.1\|1893347_1895765_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
CP026962.1\|AVG64408.1\|1882658_1884320_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.63186e-123
CP026962.1\|AVG64410.1\|1886111_1892672_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	4.20221e-115
CP026962.1\|AVG64403.1\|1877061_1877853_-\|phosphotransferase	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
CP026962.1\|AVG64406.1\|1881527_1881950_-\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000542053
CP026962.1\|AVG64398.1\|1872158_1873016_-\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
CP026962.1\|AVG64405.1\|1879254_1880664_-\|dipeptidase-PepV	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
CP026962.1\|AVG64400.1\|1873491_1874568_-\|M42-family-peptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.36515e-152
CP026962.1\|AVG64401.1\|1874654_1874966_+\|peptidase	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.78628e-46
CP026962.1\|AVG64404.1\|1878402_1879251_-\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159
CP026962.1\|AVG64411.1\|1893014_1893326_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
CP026962.1\|AVG64413.1\|1896052_1897234_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
CP026962.1\|AVG65250.1\|1875090_1875933_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38932e-155
CP026962.1\|AVG64397.1\|1871533_1872130_-\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	7.47641e-48
CP026962.1\|AVG64402.1\|1876402_1877047_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.9831e-87
CP026962.1\|AVG64407.1\|1881966_1882662_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.1062e-94

>CP026962.1|AVG64405.1|1879254_1880664_-|dipeptidase-PepV
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>CP026962.1|AVG64404.1|1878402_1879251_-|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>CP026962.1|AVG64403.1|1877061_1877853_-|phosphotransferase
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>CP026962.1|AVG64402.1|1876402_1877047_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>CP026962.1|AVG65250.1|1875090_1875933_-|MBL-fold-metallo-hydrolase
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN
>CP026962.1|AVG64401.1|1874654_1874966_+|peptidase
MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>CP026962.1|AVG64400.1|1873491_1874568_-|M42-family-peptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>CP026962.1|AVG64399.1|1873115_1873427_-|thioredoxin
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>CP026962.1|AVG64398.1|1872158_1873016_-|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>CP026962.1|AVG64397.1|1871533_1872130_-|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE
>CP026962.1|AVG64406.1|1881527_1881950_-|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFKEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>CP026962.1|AVG64407.1|1881966_1882662_-|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>CP026962.1|AVG64408.1|1882658_1884320_-|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>CP026962.1|AVG64409.1|1884726_1885995_+|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>CP026962.1|AVG64410.1|1886111_1892672_-|DUF1542-domain-containing-protein
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDVVSNNTALNVPTKTNENGSGGHLTLKEIQEDVRHSSNKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAVGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPTVNVVNNLPGFTLINGGKVGVFSHAMVRTSMFDSGDNKNYQAQGNVIALGRIHGTDTNDHGDFNGIEKALTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVFVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRTVTFNETLTYKTYTQDFINSAAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQAYIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNANVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDTRNVVNDKAREAITNINATTGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKTKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>CP026962.1|AVG64411.1|1893014_1893326_-|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>CP026962.1|AVG64412.1|1893347_1895765_-|leucine--tRNA-ligase
MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>CP026962.1|AVG64413.1|1896052_1897234_-|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>CP026962.1|AVG64414.1|1897343_1898297_+|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>CP026962.1|AVG64415.1|1898293_1898857_+|methyltransferase-domain-containing-protein
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS

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Crispr_ID: CP026962_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_8

2037797-2037875

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP026962_8

>merge|CP026962|8|2037797-2037875|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCACATTATCGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACCTGCA

>CP026962|8|6|2037797-2037875|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCA	CATTATCGTAAGCTGACTTTTCGTCAGCTTCTG
TGTTGGGGCCCCGCCAACCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG64555.1\|2043423_2043978_+\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP026962.1\|AVG64548.1\|2036855_2037614_-\|methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
CP026962.1\|AVG64542.1\|2031991_2032267_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64553.1\|2042534_2043035_+\|non-heme-ferritin	unknown	unknown	gnl\|CDD\|224445
CP026962.1\|AVG64549.1\|2038141_2039128_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
CP026962.1\|AVG64552.1\|2040929_2042243_-\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
CP026962.1\|AVG64546.1\|2035536_2036238_-\|transporter	unknown	unknown	gnl\|CDD\|227100
CP026962.1\|AVG64539.1\|2029914_2031171_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
CP026962.1\|AVG64545.1\|2034496_2035540_-\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
CP026962.1\|AVG64540.1\|2031173_2031374_-\|DUF1128-domain-containing-protein	unknown	unknown	gnl\|CDD\|227177
CP026962.1\|AVG64554.1\|2043116_2043209_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64544.1\|2033877_2034507_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225107
CP026962.1\|AVG64543.1\|2032544_2033762_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
CP026962.1\|AVG64547.1\|2036252_2036639_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64551.1\|2040196_2040928_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
CP026962.1\|AVG64556.1\|2044045_2045116_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP026962.1\|AVG64550.1\|2040000_2040111_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64557.1\|2045362_2045893_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
CP026962.1\|AVG64541.1\|2031520_2031985_+\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319971
CP026962.1\|AVG65257.1\|2039558_2039972_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG64555.1\|2043423_2043978_+\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
CP026962.1\|AVG64548.1\|2036855_2037614_-\|methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP026962.1\|AVG64553.1\|2042534_2043035_+\|non-heme-ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP026962.1\|AVG64549.1\|2038141_2039128_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
CP026962.1\|AVG64546.1\|2035536_2036238_-\|transporter	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP026962.1\|AVG64539.1\|2029914_2031171_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP026962.1\|AVG64545.1\|2034496_2035540_-\|two-component-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP026962.1\|AVG64540.1\|2031173_2031374_-\|DUF1128-domain-containing-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24
CP026962.1\|AVG64544.1\|2033877_2034507_-\|DNA-binding-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
CP026962.1\|AVG64543.1\|2032544_2033762_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
CP026962.1\|AVG64557.1\|2045362_2045893_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
CP026962.1\|AVG64551.1\|2040196_2040928_-\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
CP026962.1\|AVG64556.1\|2044045_2045116_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP026962.1\|AVG64552.1\|2040929_2042243_-\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
CP026962.1\|AVG64541.1\|2031520_2031985_+\|protein-tyrosine-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65

>CP026962.1|AVG64548.1|2036855_2037614_-|methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP026962.1|AVG64547.1|2036252_2036639_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP026962.1|AVG64546.1|2035536_2036238_-|transporter
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP026962.1|AVG64545.1|2034496_2035540_-|two-component-sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP026962.1|AVG64544.1|2033877_2034507_-|DNA-binding-response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP026962.1|AVG64543.1|2032544_2033762_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP026962.1|AVG64542.1|2031991_2032267_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP026962.1|AVG64541.1|2031520_2031985_+|protein-tyrosine-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP026962.1|AVG64540.1|2031173_2031374_-|DUF1128-domain-containing-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>CP026962.1|AVG64539.1|2029914_2031171_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>CP026962.1|AVG64549.1|2038141_2039128_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP026962.1|AVG65257.1|2039558_2039972_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>CP026962.1|AVG64550.1|2040000_2040111_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>CP026962.1|AVG64551.1|2040196_2040928_-|glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP026962.1|AVG64552.1|2040929_2042243_-|DUF1727-domain-containing-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP026962.1|AVG64553.1|2042534_2043035_+|non-heme-ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP026962.1|AVG64554.1|2043116_2043209_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>CP026962.1|AVG64555.1|2043423_2043978_+|DNA-polymerase-III-subunit-epsilon
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP026962.1|AVG64556.1|2044045_2045116_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP026962.1|AVG64557.1|2045362_2045893_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: CP026962_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_9

2229878-2229967

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP026962_9

>merge|CP026962|9|2229878-2229967|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP026962|9|7|2229878-2229967|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG64743.1\|2232519_2232612_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64730.1\|2221190_2221634_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
CP026962.1\|AVG64748.1\|2239314_2241447_+\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
CP026962.1\|AVG64747.1\|2237741_2239280_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
CP026962.1\|AVG64741.1\|2230832_2231036_-\|resolvase	unknown	unknown	gnl\|CDD\|239737
CP026962.1\|AVG64742.1\|2231094_2232231_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|366887
CP026962.1\|AVG64746.1\|2235255_2237061_-\|glutamine--fructose-6-phosphate-aminotransferase	unknown	unknown	gnl\|CDD\|234729
CP026962.1\|AVG64736.1\|2226384_2227050_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
CP026962.1\|AVG64744.1\|2233316_2234174_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
CP026962.1\|AVG64737.1\|2227201_2227522_+\|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP026962.1\|AVG64734.1\|2225010_2225868_-\|mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
CP026962.1\|AVG64739.1\|2228769_2229861_+\|transcriptional-regulator	unknown	unknown	unknown
CP026962.1\|AVG64731.1\|2221833_2222247_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
CP026962.1\|AVG64745.1\|2234241_2235024_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
CP026962.1\|AVG64733.1\|2224749_2224980_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64749.1\|2241458_2241893_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP026962.1\|AVG64735.1\|2225803_2226028_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224399
CP026962.1\|AVG64740.1\|2230303_2230408_-\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64732.1\|2222704_2224078_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
CP026962.1\|AVG64738.1\|2227523_2228504_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG64730.1\|2221190_2221634_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP026962.1\|AVG64748.1\|2239314_2241447_+\|PRD-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
CP026962.1\|AVG64747.1\|2237741_2239280_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP026962.1\|AVG64746.1\|2235255_2237061_-\|glutamine--fructose-6-phosphate-aminotransferase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP026962.1\|AVG64736.1\|2226384_2227050_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
CP026962.1\|AVG64744.1\|2233316_2234174_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
CP026962.1\|AVG64737.1\|2227201_2227522_+\|ArsR-family-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP026962.1\|AVG64734.1\|2225010_2225868_-\|mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	3.9165e-114
CP026962.1\|AVG64741.1\|2230832_2231036_-\|resolvase	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.06615e-14
CP026962.1\|AVG64731.1\|2221833_2222247_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
CP026962.1\|AVG64745.1\|2234241_2235024_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.86955e-104
CP026962.1\|AVG64749.1\|2241458_2241893_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
CP026962.1\|AVG64735.1\|2225803_2226028_-\|hypothetical-protein	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.6805e-08
CP026962.1\|AVG64742.1\|2231094_2232231_-\|DNA-binding-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.8303e-06
CP026962.1\|AVG64732.1\|2222704_2224078_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
CP026962.1\|AVG64738.1\|2227523_2228504_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108

>CP026962.1|AVG64739.1|2228769_2229861_+|transcriptional-regulator
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP026962.1|AVG64738.1|2227523_2228504_+|cation-transporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>CP026962.1|AVG64737.1|2227201_2227522_+|ArsR-family-transcriptional-regulator
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP026962.1|AVG64736.1|2226384_2227050_-|SDR-family-NAD(P)-dependent-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>CP026962.1|AVG64735.1|2225803_2226028_-|hypothetical-protein
MRTKSKYNGTTTSEFYCLLNHNGGATMPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGGMLVCVSTSKWYERDY
>CP026962.1|AVG64734.1|2225010_2225868_-|mannose-6-phosphate-isomerase
MIQLGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP026962.1|AVG64733.1|2224749_2224980_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP026962.1|AVG64732.1|2222704_2224078_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP026962.1|AVG64731.1|2221833_2222247_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP026962.1|AVG64730.1|2221190_2221634_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP026962.1|AVG64740.1|2230303_2230408_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>CP026962.1|AVG64741.1|2230832_2231036_-|resolvase
MIVYQRKINIDTLKEFGCGCVYSERISGVKRTELVKCLNYLRESDTLVVYQLDRLGRTTKLLIELSQ
>CP026962.1|AVG64742.1|2231094_2232231_-|DNA-binding-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPIKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>CP026962.1|AVG64743.1|2232519_2232612_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>CP026962.1|AVG64744.1|2233316_2234174_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>CP026962.1|AVG64745.1|2234241_2235024_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP026962.1|AVG64746.1|2235255_2237061_-|glutamine--fructose-6-phosphate-aminotransferase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP026962.1|AVG64747.1|2237741_2239280_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP026962.1|AVG64748.1|2239314_2241447_+|PRD-domain-containing-protein
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP026962.1|AVG64749.1|2241458_2241893_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Crispr_ID: CP026962_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP026962_10

2353805-2353998

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of CP026962_10

>merge|CP026962|10|2353805-2353998|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>CP026962|10|3|2353805-2353998|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
CP026962.1\|AVG64851.1\|2344739_2345057_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64867.1\|2358290_2358785_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
CP026962.1\|AVG64870.1\|2360497_2361103_-\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226628
CP026962.1\|AVG64852.1\|2345243_2348411_-\|AcrB/AcrD/AcrF-family-protein	unknown	unknown	gnl\|CDD\|223911
CP026962.1\|AVG64853.1\|2348527_2349793_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
CP026962.1\|AVG64863.1\|2355787_2356021_-\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|340452
CP026962.1\|AVG64866.1\|2356968_2358228_-\|molybdopterin-molybdenumtransferase	unknown	unknown	gnl\|CDD\|238452
CP026962.1\|AVG64858.1\|2353098_2353449_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
CP026962.1\|AVG64861.1\|2354139_2355162_-\|cyclic-pyranopterin-monophosphate-synthase	unknown	unknown	gnl\|CDD\|274250
CP026962.1\|AVG64850.1\|2344330_2344495_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64869.1\|2359323_2360328_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
CP026962.1\|AVG64864.1\|2356026_2356473_-\|molybdopterin-synthase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223391
CP026962.1\|AVG64859.1\|2353574_2353745_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64862.1\|2355181_2355781_-\|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
CP026962.1\|AVG64865.1\|2356486_2356972_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
CP026962.1\|AVG64856.1\|2351350_2351791_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
CP026962.1\|AVG64855.1\|2350424_2351189_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
CP026962.1\|AVG64868.1\|2358786_2359293_-\|molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223595
CP026962.1\|AVG64854.1\|2350181_2350433_+\|hypothetical-protein	unknown	unknown	unknown
CP026962.1\|AVG64857.1\|2351783_2352995_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042

Protein	Function_ID	Function_description	E-value
CP026962.1\|AVG64867.1\|2358290_2358785_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
CP026962.1\|AVG64870.1\|2360497_2361103_-\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
CP026962.1\|AVG64852.1\|2345243_2348411_-\|AcrB/AcrD/AcrF-family-protein	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
CP026962.1\|AVG64853.1\|2348527_2349793_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
CP026962.1\|AVG64863.1\|2355787_2356021_-\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
CP026962.1\|AVG64866.1\|2356968_2358228_-\|molybdopterin-molybdenumtransferase	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
CP026962.1\|AVG64858.1\|2353098_2353449_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
CP026962.1\|AVG64869.1\|2359323_2360328_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
CP026962.1\|AVG64864.1\|2356026_2356473_-\|molybdopterin-synthase-catalytic-subunit	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
CP026962.1\|AVG64861.1\|2354139_2355162_-\|cyclic-pyranopterin-monophosphate-synthase	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
CP026962.1\|AVG64862.1\|2355181_2355781_-\|molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
CP026962.1\|AVG64865.1\|2356486_2356972_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
CP026962.1\|AVG64856.1\|2351350_2351791_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
CP026962.1\|AVG64855.1\|2350424_2351189_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
CP026962.1\|AVG64868.1\|2358786_2359293_-\|molybdenum-cofactor-biosynthesis-protein	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
CP026962.1\|AVG64857.1\|2351783_2352995_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72

>CP026962.1|AVG64859.1|2353574_2353745_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>CP026962.1|AVG64858.1|2353098_2353449_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>CP026962.1|AVG64857.1|2351783_2352995_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>CP026962.1|AVG64856.1|2351350_2351791_+|MarR-family-transcriptional-regulator
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>CP026962.1|AVG64855.1|2350424_2351189_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>CP026962.1|AVG64854.1|2350181_2350433_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>CP026962.1|AVG64853.1|2348527_2349793_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>CP026962.1|AVG64852.1|2345243_2348411_-|AcrB/AcrD/AcrF-family-protein
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>CP026962.1|AVG64851.1|2344739_2345057_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>CP026962.1|AVG64850.1|2344330_2344495_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>CP026962.1|AVG64861.1|2354139_2355162_-|cyclic-pyranopterin-monophosphate-synthase
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>CP026962.1|AVG64862.1|2355181_2355781_-|molybdenum-cofactor-guanylyltransferase
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>CP026962.1|AVG64863.1|2355787_2356021_-|molybdopterin-synthase-sulfur-carrier-subunit
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>CP026962.1|AVG64864.1|2356026_2356473_-|molybdopterin-synthase-catalytic-subunit
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>CP026962.1|AVG64865.1|2356486_2356972_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>CP026962.1|AVG64866.1|2356968_2358228_-|molybdopterin-molybdenumtransferase
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>CP026962.1|AVG64867.1|2358290_2358785_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>CP026962.1|AVG64868.1|2358786_2359293_-|molybdenum-cofactor-biosynthesis-protein
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>CP026962.1|AVG64869.1|2359323_2360328_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>CP026962.1|AVG64870.1|2360497_2361103_-|molybdenum-ABC-transporter-ATP-binding-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP026962_4	4.1\|962149\|34\|CP026962\|CRISPRCasFinder	962149-962182	34	CP026962.1	1437317-1437350	0	1.0
CP026962_4	4.1\|962149\|34\|CP026962\|CRISPRCasFinder	962149-962182	34	CP026962.1	1525759-1525792	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	98953-98972	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	256772-256791	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	399970-399989	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	482866-482885	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	913404-913423	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	913459-913478	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	919064-919083	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	919122-919141	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	919180-919199	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	962203-962222	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1030661-1030680	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1154647-1154666	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1437218-1437237	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1525872-1525891	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1702235-1702254	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1880938-1880957	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	2039227-2039246	0	1.0
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	2545649-2545668	0	1.0
CP026962_10	10.2\|2353884\|36\|CP026962\|CRT	2353884-2353919	36	CP026962.1	1229109-1229144	0	1.0
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	918849-918874	1	0.962
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	1010954-1010979	1	0.962
CP026962_5	5.3\|1011124\|26\|CP026962\|CRT	1011124-1011149	26	CP026962.1	918905-918930	1	0.962
CP026962_5	5.3\|1011124\|26\|CP026962\|CRT	1011124-1011149	26	CP026962.1	918961-918986	1	0.962
CP026962_7	7.1\|1881052\|21\|CP026962\|CRT	1881052-1881072	21	CP026962.1	1880993-1881013	1	0.952
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	400024-400043	1	0.95
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	926270-926289	1	0.95
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1229113-1229132	1	0.95
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1486544-1486563	1	0.95
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	1736201-1736220	1	0.95
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	2048576-2048595	1	0.95
CP026962_7	7.3\|1881169\|18\|CP026962\|CRT	1881169-1881186	18	CP026962.1	1880996-1881013	1	0.944
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	918885-918917	1	0.97
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	918941-918973	1	0.97
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	1437272-1437304	1	0.97
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	1702284-1702316	1	0.97
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	2631220-2631252	1	0.97
CP026962_10	10.2\|2353884\|36\|CP026962\|CRT	2353884-2353919	36	CP026962.1	1880934-1880969	1	0.972
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	98853-98878	2	0.923
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	98909-98934	2	0.923
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	882269-882294	2	0.923
CP026962_5	5.1\|1011010\|26\|CP026962\|CRT	1011010-1011035	26	CP026962.1	1229151-1229176	2	0.923
CP026962_5	5.3\|1011124\|26\|CP026962\|CRT	1011124-1011149	26	CP026962.1	482735-482760	2	0.923
CP026962_7	7.2\|1881111\|20\|CP026962\|CRT	1881111-1881130	20	CP026962.1	886869-886888	2	0.9
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	CP026962.1	1525805-1525837	2	0.939
CP026962_10	10.1\|2353828\|33\|CP026962\|CRT	2353828-2353860	33	CP026962.1	918885-918917	2	0.939
CP026962_10	10.1\|2353828\|33\|CP026962\|CRT	2353828-2353860	33	CP026962.1	918941-918973	2	0.939
CP026962_10	10.1\|2353828\|33\|CP026962\|CRT	2353828-2353860	33	CP026962.1	1437272-1437304	2	0.939
CP026962_10	10.1\|2353828\|33\|CP026962\|CRT	2353828-2353860	33	CP026962.1	1525805-1525837	2	0.939
CP026962_10	10.1\|2353828\|33\|CP026962\|CRT	2353828-2353860	33	CP026962.1	2631220-2631252	2	0.939
CP026962_10	10.2\|2353884\|36\|CP026962\|CRT	2353884-2353919	36	CP026962.1	1702223-1702258	2	0.944
CP026962_10	10.2\|2353884\|36\|CP026962\|CRT	2353884-2353919	36	CP026962.1	2048564-2048599	2	0.944
CP026962_10	10.3\|2353943\|33\|CP026962\|CRT	2353943-2353975	33	CP026962.1	918829-918861	2	0.939
CP026962_10	10.3\|2353943\|33\|CP026962\|CRT	2353943-2353975	33	CP026962.1	918885-918917	2	0.939
CP026962_10	10.3\|2353943\|33\|CP026962\|CRT	2353943-2353975	33	CP026962.1	918941-918973	2	0.939
CP026962_10	10.3\|2353943\|33\|CP026962\|CRT	2353943-2353975	33	CP026962.1	1437272-1437304	2	0.939
CP026962_10	10.3\|2353943\|33\|CP026962\|CRT	2353943-2353975	33	CP026962.1	2631220-2631252	2	0.939

1. spacer 4.1|962149|34|CP026962|CRISPRCasFinder matches to position: 1437317-1437350, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 4.1|962149|34|CP026962|CRISPRCasFinder matches to position: 1525759-1525792, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 7.2|1881111|20|CP026962|CRT matches to position: 98953-98972, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

4. spacer 7.2|1881111|20|CP026962|CRT matches to position: 256772-256791, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

5. spacer 7.2|1881111|20|CP026962|CRT matches to position: 399970-399989, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

6. spacer 7.2|1881111|20|CP026962|CRT matches to position: 482866-482885, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

7. spacer 7.2|1881111|20|CP026962|CRT matches to position: 913404-913423, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

8. spacer 7.2|1881111|20|CP026962|CRT matches to position: 913459-913478, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

9. spacer 7.2|1881111|20|CP026962|CRT matches to position: 919064-919083, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

10. spacer 7.2|1881111|20|CP026962|CRT matches to position: 919122-919141, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

11. spacer 7.2|1881111|20|CP026962|CRT matches to position: 919180-919199, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

12. spacer 7.2|1881111|20|CP026962|CRT matches to position: 962203-962222, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

13. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1030661-1030680, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

14. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1154647-1154666, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

15. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1437218-1437237, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

16. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1525872-1525891, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

17. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1702235-1702254, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

18. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1880938-1880957, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

19. spacer 7.2|1881111|20|CP026962|CRT matches to position: 2039227-2039246, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

20. spacer 7.2|1881111|20|CP026962|CRT matches to position: 2545649-2545668, mismatch: 0, identity: 1.0

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaagaaattct	Protospacer
********************

21. spacer 10.2|2353884|36|CP026962|CRT matches to position: 1229109-1229144, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

22. spacer 5.1|1011010|26|CP026962|CRT matches to position: 918849-918874, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*****************.********

23. spacer 5.1|1011010|26|CP026962|CRT matches to position: 1010954-1010979, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

24. spacer 5.3|1011124|26|CP026962|CRT matches to position: 918905-918930, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

25. spacer 5.3|1011124|26|CP026962|CRT matches to position: 918961-918986, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

26. spacer 7.1|1881052|21|CP026962|CRT matches to position: 1880993-1881013, mismatch: 1, identity: 0.952

agctggccaatagtcagcttt	CRISPR spacer
agctggccaatagttagcttt	Protospacer
**************.******

27. spacer 7.2|1881111|20|CP026962|CRT matches to position: 400024-400043, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gaaattcgaaaagaaattct	Protospacer
*** ****************

28. spacer 7.2|1881111|20|CP026962|CRT matches to position: 926270-926289, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaatgaaattct	Protospacer
*********** ********

29. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1229113-1229132, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcaaaaagaaattct	Protospacer
*******.************

30. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1486544-1486563, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gattttcgaaaagaaattct	Protospacer
** *****************

31. spacer 7.2|1881111|20|CP026962|CRT matches to position: 1736201-1736220, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgtaaagaaattct	Protospacer
******** ***********

32. spacer 7.2|1881111|20|CP026962|CRT matches to position: 2048576-2048595, mismatch: 1, identity: 0.95

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcgaaaggaaattct	Protospacer
***********.********

33. spacer 7.3|1881169|18|CP026962|CRT matches to position: 1880996-1881013, mismatch: 1, identity: 0.944

tggccaatagtcagcttt	CRISPR spacer
tggccaatagttagcttt	Protospacer
***********.******

34. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 918885-918917, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

35. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 918941-918973, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

36. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 1437272-1437304, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

37. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 1702284-1702316, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattatagtaagctgacttttcgtcagcttctg	Protospacer
****** **************************

38. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 2631220-2631252, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

39. spacer 10.2|2353884|36|CP026962|CRT matches to position: 1880934-1880969, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

40. spacer 5.1|1011010|26|CP026962|CRT matches to position: 98853-98878, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

41. spacer 5.1|1011010|26|CP026962|CRT matches to position: 98909-98934, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacaaagaagctggcgg	Protospacer
************* ***.********

42. spacer 5.1|1011010|26|CP026962|CRT matches to position: 882269-882294, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

43. spacer 5.1|1011010|26|CP026962|CRT matches to position: 1229151-1229176, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

44. spacer 5.3|1011124|26|CP026962|CRT matches to position: 482735-482760, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

45. spacer 7.2|1881111|20|CP026962|CRT matches to position: 886869-886888, mismatch: 2, identity: 0.9

gaatttcgaaaagaaattct	CRISPR spacer
gaatttcaaaaaggaattct	Protospacer
*******.*****.******

46. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to position: 1525805-1525837, mismatch: 2, identity: 0.939

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
******.******************* ******

47. spacer 10.1|2353828|33|CP026962|CRT matches to position: 918885-918917, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

48. spacer 10.1|2353828|33|CP026962|CRT matches to position: 918941-918973, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

49. spacer 10.1|2353828|33|CP026962|CRT matches to position: 1437272-1437304, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

50. spacer 10.1|2353828|33|CP026962|CRT matches to position: 1525805-1525837, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

51. spacer 10.1|2353828|33|CP026962|CRT matches to position: 2631220-2631252, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

52. spacer 10.2|2353884|36|CP026962|CRT matches to position: 1702223-1702258, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

53. spacer 10.2|2353884|36|CP026962|CRT matches to position: 2048564-2048599, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

54. spacer 10.3|2353943|33|CP026962|CRT matches to position: 918829-918861, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgactttccgccagcttctg	Protospacer
*********************.*.*********

55. spacer 10.3|2353943|33|CP026962|CRT matches to position: 918885-918917, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

56. spacer 10.3|2353943|33|CP026962|CRT matches to position: 918941-918973, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

57. spacer 10.3|2353943|33|CP026962|CRT matches to position: 1437272-1437304, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

58. spacer 10.3|2353943|33|CP026962|CRT matches to position: 2631220-2631252, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP026962_5	5.4\|1011180\|53\|CP026962\|CRT	1011180-1011232	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
CP026962_5	5.3\|1011124\|26\|CP026962\|CRT	1011124-1011149	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
CP026962_8	8.1\|2037820\|33\|CP026962\|CRISPRCasFinder	2037820-2037852	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 5.4|1011180|53|CP026962|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

2. spacer 5.3|1011124|26|CP026962|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

3. spacer 8.1|2037820|33|CP026962|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
ttttatcgtaaggtgagttttcgtcaagcacct	Protospacer
. ********** *** *********. . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

850960 : 858780

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG63422.1\|850960_852016_-	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
AVG63423.1\|852015_852702_-	DNA-binding response regulator	NA	NA	NA	NA
AVG63424.1\|852676_853150_-	DoxX family protein	NA	NA	NA	NA
AVG63425.1\|853491_853932_-	hypothetical protein	NA	NA	NA	NA
AVG63426.1\|854211_854796_-	hypothetical protein	NA	NA	NA	NA
AVG63427.1\|854894_855608_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AVG63428.1\|855611_856031_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
AVG63429.1\|856032_856701_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AVG63430.1\|857051_857645_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AVG63431.1\|857628_858780_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_2

870752 : 885483

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG63441.1\|870752_871811_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
AVG63442.1\|872161_872704_+	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AVG63443.1\|872816_872915_+	hypothetical protein	NA	NA	NA	NA
AVG63444.1\|873327_874245_-	lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
AVG63445.1\|874335_874437_+	hypothetical protein	NA	NA	NA	NA
AVG63446.1\|874514_876020_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AVG63447.1\|876085_876331_-	hypothetical protein	NA	NA	NA	NA
AVG63448.1\|876360_876861_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AVG63449.1\|876880_877747_-	EamA/RhaT family transporter	NA	NA	NA	NA
AVG63450.1\|878131_878398_+	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
AVG63451.1\|878547_878946_+	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AVG63452.1\|878908_881014_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AVG63453.1\|881131_882103_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AVG63454.1\|882235_882340_+	hypothetical protein	NA	NA	NA	NA
AVG63455.1\|882616_882772_+	hypothetical protein	NA	NA	NA	NA
AVG65225.1\|882810_883782_+	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AVG63456.1\|883768_884725_+	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AVG63457.1\|884721_885483_+	iron ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

1056115 : 1110993

Streptococcus_phage(28.57%)

holin,tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG63628.1\|1056115_1057105_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AVG63629.1\|1057399_1057795_+	transcriptional regulator Spx	NA	NA	NA	NA
AVG63630.1\|1058165_1058885_+	adaptor protein MecA	NA	NA	NA	NA
AVG63631.1\|1059005_1059992_+	competence protein CoiA	NA	NA	NA	NA
AVG63632.1\|1060039_1061848_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	9.3e-47	24.4
AVG63633.1\|1062307_1063114_-	DsbA family protein	NA	NA	NA	NA
AVG63634.1\|1063136_1063502_-	globin	NA	NA	NA	NA
AVG63635.1\|1063605_1064199_-	CYTH domain-containing protein	NA	NA	NA	NA
AVG63636.1\|1064384_1064732_+	hypothetical protein	NA	NA	NA	NA
AVG63637.1\|1064748_1065384_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
AVG63638.1\|1065400_1066210_+	NAD(+) kinase	NA	NA	NA	NA
AVG63639.1\|1066206_1067061_+	RluA family pseudouridine synthase	NA	NA	NA	NA
AVG63640.1\|1067081_1068467_+	magnesium transporter	NA	NA	NA	NA
AVG63641.1\|1068476_1070321_+	sodium:proton antiporter	NA	NA	NA	NA
AVG63642.1\|1070598_1071369_+	enoyl-[acyl-carrier-protein] reductase FabI	NA	NA	NA	NA
AVG63643.1\|1071563_1072649_-	AI-2E family transporter	NA	NA	NA	NA
AVG63644.1\|1072990_1074559_+	alanine:cation symporter family protein	NA	NA	NA	NA
AVG63645.1\|1074700_1075459_+	esterase family protein	NA	NA	NA	NA
AVG63646.1\|1075652_1076162_+	hypothetical protein	NA	NA	NA	NA
AVG63647.1\|1076274_1077483_-	MFS transporter	NA	NA	NA	NA
AVG63648.1\|1077442_1078618_-	diacylglycerol beta-glucosyltransferase	NA	NA	NA	NA
AVG63649.1\|1079050_1080532_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
AVG63650.1\|1080515_1080776_+	hypothetical protein	NA	NA	NA	NA
AVG63651.1\|1080775_1082338_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	4.9e-36	28.2
AVG63652.1\|1082639_1083443_+	hypothetical protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
AVG63653.1\|1083661_1085986_+\|protease	serine protease	W5SAB9	Pithovirus	8.1e-11	27.1
AVG63654.1\|1086002_1087361_+	Ktr system potassium uptake protein D	NA	NA	NA	NA
AVG63655.1\|1087499_1089011_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
AVG63656.1\|1089497_1090067_-	competence protein ComK	NA	NA	NA	NA
AVG63657.1\|1090276_1090495_+	IDEAL domain-containing protein	NA	NA	NA	NA
AVG63658.1\|1090575_1091562_-	lipoate--protein ligase	NA	NA	NA	NA
AVG63659.1\|1091760_1091937_+	DUF2187 domain-containing protein	NA	NA	NA	NA
AVG63660.1\|1091951_1092554_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVG65229.1\|1092854_1092932_+\|holin	putative holin-like toxin	NA	NA	NA	NA
AVG63661.1\|1093470_1093572_+	hypothetical protein	NA	NA	NA	NA
AVG65230.1\|1093581_1093854_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
AVG63662.1\|1093897_1095862_+	DUF1430 domain-containing protein	NA	NA	NA	NA
AVG63663.1\|1095864_1096185_+	hypothetical protein	NA	NA	NA	NA
AVG63664.1\|1096181_1096823_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-19	33.7
AVG63665.1\|1096910_1097201_-	hypothetical protein	NA	NA	NA	NA
AVG63666.1\|1097479_1097767_+	hypothetical protein	NA	NA	NA	NA
AVG63667.1\|1097772_1099254_+	glycosyl transferase family 1	NA	NA	NA	NA
AVG63668.1\|1099342_1099699_-	DoxX family protein	NA	NA	NA	NA
AVG63669.1\|1100186_1101146_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AVG63670.1\|1101191_1101323_-	hypothetical protein	NA	NA	NA	NA
AVG63671.1\|1101386_1101677_-	NINE protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
AVG63672.1\|1101766_1102318_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AVG63673.1\|1102368_1103307_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
AVG63674.1\|1103457_1103562_+	hypothetical protein	NA	NA	NA	NA
AVG63675.1\|1103638_1104850_+	isochorismate synthase	NA	NA	NA	NA
AVG63676.1\|1104836_1106510_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase	NA	NA	NA	NA
AVG63677.1\|1106496_1107300_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
AVG63678.1\|1107292_1108114_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AVG63679.1\|1108352_1108682_-	staphostatin B	NA	NA	NA	NA
AVG63680.1\|1108719_1109901_-\|protease	cysteine protease staphopain B	NA	NA	NA	NA
AVG63681.1\|1109982_1110993_-\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	6.2e-16	32.3

DBSCAN-SWA_4

1129888 : 1138361

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG63698.1\|1129888_1130371_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
AVG63699.1\|1130357_1131482_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AVG63700.1\|1131485_1132190_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AVG63701.1\|1132189_1132453_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVG63702.1\|1132454_1133126_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVG63703.1\|1133118_1135308_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
AVG63704.1\|1135286_1136771_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
AVG63705.1\|1136763_1137792_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
AVG63706.1\|1137794_1138361_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_5

1673845 : 1682157

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG64214.1\|1673845_1674631_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AVG64215.1\|1674756_1675647_-	endonuclease	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AVG64216.1\|1675656_1677003_-	DEAD/DEAH box family ATP-dependent RNA helicase	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
AVG64217.1\|1677116_1678217_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AVG64218.1\|1678219_1678897_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
AVG64219.1\|1679027_1680134_-	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AVG64220.1\|1680357_1682157_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_6

1751295 : 1760338

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG64290.1\|1751295_1751814_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AVG64291.1\|1751835_1754109_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
AVG64292.1\|1754311_1756591_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AVG64293.1\|1756865_1757126_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AVG64294.1\|1757144_1758284_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AVG64295.1\|1758306_1759332_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AVG64296.1\|1759333_1760338_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1886111 : 1967599

Staphylococcus_phage(93.55%)

transposase,tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG64410.1\|1886111_1892672_-	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	3.4e-304	98.1
AVG64411.1\|1893014_1893326_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
AVG64412.1\|1893347_1895765_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
AVG64413.1\|1896052_1897234_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
AVG64414.1\|1897343_1898297_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
AVG64415.1\|1898293_1898857_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AVG64416.1\|1898976_1899378_-	MarR family transcriptional regulator	NA	NA	NA	NA
AVG64417.1\|1900956_1901784_-	alpha/beta hydrolase	NA	NA	NA	NA
AVG64418.1\|1901786_1901906_-	hypothetical protein	NA	NA	NA	NA
AVG64419.1\|1901917_1902109_-	hypothetical protein	NA	NA	NA	NA
AVG64420.1\|1902017_1903019_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
AVG64421.1\|1903140_1903605_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AVG64422.1\|1903617_1904799_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AVG64423.1\|1904809_1905442_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AVG65251.1\|1905448_1906480_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.8e-197	99.4
AVG64424.1\|1906972_1908475_-	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
AVG64425.1\|1908997_1909312_+	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
AVG64426.1\|1909311_1910604_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	1.9e-227	99.3
AVG64427.1\|1910621_1911017_+	protein ArsC	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
AVG64428.1\|1911311_1912166_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AVG64429.1\|1912441_1912666_-	hypothetical protein	NA	NA	NA	NA
AVG64430.1\|1912864_1913335_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	3.3e-81	98.1
AVG64431.1\|1913447_1913891_+	competence protein ComK	NA	NA	NA	NA
AVG64432.1\|1913877_1914321_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
AVG64433.1\|1914616_1915252_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AVG64434.1\|1915691_1916405_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AVG64435.1\|1916664_1916967_+	hypothetical protein	NA	NA	NA	NA
AVG64436.1\|1917222_1917588_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AVG64437.1\|1917584_1917938_+	camphor resistance protein CrcB	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
AVG64438.1\|1920021_1920855_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
AVG64439.1\|1921066_1921975_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
AVG64440.1\|1922099_1923293_-	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AVG64441.1\|1923663_1925256_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AVG64442.1\|1925391_1925877_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
AVG65252.1\|1926251_1926998_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.1e-142	98.4
AVG64443.1\|1927002_1927476_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
AVG64444.1\|1927541_1927799_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AVG64445.1\|1927795_1928797_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
AVG64446.1\|1928801_1930280_-	2-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
AVG65253.1\|1930438_1930894_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
AVG64447.1\|1931196_1931847_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
AVG64448.1\|1931927_1932923_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
AVG64449.1\|1932998_1933625_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
AVG64450.1\|1933665_1934010_+	DUF3969 domain-containing protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
AVG64451.1\|1934107_1934659_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
AVG64452.1\|1934876_1935518_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
AVG64453.1\|1935631_1935817_-	hypothetical protein	NA	NA	NA	NA
AVG64454.1\|1935818_1935995_-	hypothetical protein	NA	NA	NA	NA
AVG64455.1\|1936005_1936389_-	hypothetical protein	NA	NA	NA	NA
AVG64456.1\|1936580_1936790_-\|transposase	transposase	A0A2H4PQV6	Staphylococcus_phage	1.4e-31	100.0
AVG64457.1\|1936992_1937136_-	hypothetical protein	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
AVG64458.1\|1937556_1937658_+	hypothetical protein	NA	NA	NA	NA
AVG65254.1\|1938005_1938365_-	DUF1433 domain-containing protein	NA	NA	NA	NA
AVG64459.1\|1938902_1943015_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
AVG64460.1\|1943864_1945064_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	8.5e-230	100.0
AVG64461.1\|1945056_1946796_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
AVG64462.1\|1946776_1946911_-	hypothetical protein	NA	NA	NA	NA
AVG64463.1\|1946975_1947695_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
AVG64464.1\|1947845_1948562_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
AVG64465.1\|1948663_1948771_+	hypothetical protein	NA	NA	NA	NA
AVG64466.1\|1948719_1949439_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
AVG64467.1\|1949559_1950279_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
AVG64468.1\|1950336_1951059_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
AVG64469.1\|1951183_1951891_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
AVG64470.1\|1952326_1952545_-	hypothetical protein	NA	NA	NA	NA
AVG64471.1\|1952854_1953421_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
AVG64472.1\|1953894_1954593_-	BsaG protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
AVG64473.1\|1954589_1955351_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
AVG64474.1\|1955347_1956040_-	lantibiotic ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
AVG64475.1\|1956062_1957436_-	peptidase S8	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
AVG64476.1\|1957445_1957964_-	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
AVG64477.1\|1957979_1959224_-	lanthionine synthetase	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
AVG64478.1\|1959216_1962210_-\|bacteriocin	bacteriocin biosynthesis protein	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
AVG64479.1\|1962274_1962418_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
AVG64480.1\|1962861_1963053_+	hypothetical protein	NA	NA	NA	NA
AVG64481.1\|1963154_1963298_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
AVG64482.1\|1963539_1964523_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
AVG65255.1\|1964524_1965430_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	3.6e-172	99.7
AVG64483.1\|1966258_1966798_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	2.0e-61	76.8
AVG64484.1\|1966810_1967599_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP026963

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2599 : 57273

Staphylococcus_phage(71.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVG65284.1\|2599_3274_+\|transposase	IS6 family transposase IS257-3	A0A0N9RU54	Staphylococcus_phage	2.2e-126	97.3
AVG65285.1\|3403_4018_+	hypothetical protein	NA	NA	NA	NA
AVG65286.1\|4086_5358_+	hypothetical protein	NA	NA	NA	NA
AVG65287.1\|5399_5816_-	YolD-like family protein	A0A2H4JEH6	uncultured_Caudovirales_phage	1.0e-33	60.9
AVG65288.1\|6110_6668_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	4.9e-31	44.9
AVG65289.1\|6949_7729_+	hypothetical protein	NA	NA	NA	NA
AVG65290.1\|7862_9479_+	hypothetical protein	NA	NA	NA	NA
AVG65291.1\|9489_9678_+	hypothetical protein	NA	NA	NA	NA
AVG65292.1\|9681_11406_+	LtrC	NA	NA	NA	NA
AVG65293.1\|11446_13444_-	oriT nickase	NA	NA	NA	NA
AVG65294.1\|13647_13920_+	hypothetical protein	NA	NA	NA	NA
AVG65295.1\|14023_14257_+	hypothetical protein	NA	NA	NA	NA
AVG65296.1\|14519_15560_+	parM protein	NA	NA	NA	NA
AVG65297.1\|15562_15892_+	plasmid segregation protein ParR	NA	NA	NA	NA
AVG65298.1\|15895_16156_-	XRE family transcriptional regulator	NA	NA	NA	NA
AVG65299.1\|16536_17496_+	replication protein	NA	NA	NA	NA
AVG65300.1\|17614_18289_+\|transposase	IS6 family transposase IS257R1	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
AVG65301.1\|18312_19239_+	protein rep	NA	NA	NA	NA
AVG65302.1\|19870_20617_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
AVG65303.1\|20966_21641_+\|transposase	IS6 family transposase IS257R1	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
AVG65304.1\|21682_22558_-	protein rep	NA	NA	NA	NA
AVG65305.1\|22802_24065_-	Plasmid recombination enzyme type 2	NA	NA	NA	NA
AVG65306.1\|24571_24976_-	bleomycin binding protein	NA	NA	NA	NA
AVG65307.1\|25192_25963_-	aminoglycoside O-nucleotidyltransferase ANT(4')-Ia	NA	NA	NA	NA
AVG65308.1\|26122_26269_-	replication domain protein	A0A286QS97	Streptococcus_phage	2.7e-05	58.1
AVG65309.1\|26312_26987_+\|transposase	IS6 family transposase IS257R2	A0A0N9RU54	Staphylococcus_phage	8.1e-129	100.0
AVG65310.1\|27095_27284_-	regulator	NA	NA	NA	NA
AVG65311.1\|27455_28430_+	transfer complex protein TraA	NA	NA	NA	NA
AVG65312.1\|28446_28764_+	hypothetical protein	NA	NA	NA	NA
AVG65313.1\|28823_29231_+	hypothetical protein	NA	NA	NA	NA
AVG65314.1\|29217_29901_+	traD	NA	NA	NA	NA
AVG65315.1\|29921_31934_+	DUF87 domain-containing protein	NA	NA	NA	NA
AVG65316.1\|31945_33226_+	hypothetical protein	NA	NA	NA	NA
AVG65317.1\|33243_34320_+	CHAP domain-containing protein	W5R8Q8	Staphylococcus_phage	2.4e-10	36.8
AVG65318.1\|34329_34815_+	conjugal transfer protein TraH	NA	NA	NA	NA
AVG65319.1\|34830_36933_+	DNA topoisomerase III	F2Y1B5	Organic_Lake_phycodnavirus	1.4e-09	24.6
AVG65320.1\|36948_37413_+	hypothetical protein	NA	NA	NA	NA
AVG65321.1\|37409_39050_+	type VI secretion protein	NA	NA	NA	NA
AVG65322.1\|39127_40045_+	hypothetical protein	NA	NA	NA	NA
AVG65323.1\|40061_40454_+	single-stranded DNA-binding protein	A0A1P8VVS8	Streptococcus_phage	1.3e-14	38.4
AVG65324.1\|40715_41390_+\|transposase	IS6 family transposase IS257-1	A0A0N9RU54	Staphylococcus_phage	3.8e-126	98.2
AVG65325.1\|41493_42417_+	replication protein	NA	NA	NA	NA
AVG65326.1\|42949_43171_-	hypothetical protein	NA	NA	NA	NA
AVG65327.1\|43388_43712_-	quaternary ammonium compound efflux SMR transporter QacC	NA	NA	NA	NA
AVG65328.1\|44019_44250_+	hypothetical protein	NA	NA	NA	NA
AVG65329.1\|44279_44954_+\|transposase	IS6 family transposase IS257-1	A0A0N9RU54	Staphylococcus_phage	3.8e-126	98.2
AVG65343.1\|45445_45838_+	N-acetyltransferase	A0A0N7GFH7	Staphylococcus_phage	6.9e-72	100.0
AVG65330.1\|45838_47278_+	bifunctional aminoglycoside N-acetyltransferase AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
AVG65331.1\|47850_48516_-\|transposase	IS6 family transposase IS257-2	A0A0N9RU54	Staphylococcus_phage	5.9e-108	91.6
AVG65332.1\|48973_49648_+\|transposase	IS6 family transposase IS257-3	A0A0N9RU54	Staphylococcus_phage	2.2e-126	97.3
AVG65333.1\|49679_50102_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.0e-68	100.0
AVG65334.1\|50111_50597_-	trimethoprim-resistant dihydrofolate reductase DfrC	A0A0N9S8H6	Staphylococcus_phage	1.1e-90	100.0
AVG65335.1\|50638_51595_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.1e-190	100.0
AVG65336.1\|51708_52383_+\|transposase	IS6 family transposase IS257R2	A0A0N9RU54	Staphylococcus_phage	8.1e-129	100.0
AVG65337.1\|52822_53206_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AVG65338.1\|53187_53397_+	hypothetical protein	NA	NA	NA	NA
AVG65339.1\|53383_54394_+	protein rlx	NA	NA	NA	NA
AVG65344.1\|54506_54902_+	mobilization protein	NA	NA	NA	NA
AVG65340.1\|56598_57273_+\|transposase	IS6 family transposase IS257-3	A0A0N9RU54	Staphylococcus_phage	2.2e-126	97.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP026962

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP026963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection