CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025481	Staphylococcus aureus subsp. aureus strain 2148.N plasmid p2148.N, complete sequence	0 crisprs	csa3	0	0	0	0
CP016856	Staphylococcus aureus subsp. aureus strain 2148.N chromosome, complete genome	6 crisprs	cas3,WYL,csa3,DEDDh,DinG	3	3	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP016856_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_1

291598-291689

Orphan

Consensus_repeat	Method
CCTCTTTGATTTTTAATCATTAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP016856_1

>merge|CP016856|1|291598-291689|CRISPRCasFinder
CCTCTTTGATTTTTAATCATTAGAGGCTTTTATGCAGTGATGCGAAGCATCATCTGTATTCCGCTGTTCCTCTTTGATTTTTAATCATTATG

>CP016856|1|1|291598-291689|CRISPRCasFinder
CCTCTTTGATTTTTAATCATTAGA	GGCTTTTATGCAGTGATGCGAAGCATCATCTGTATTCCGCTGTT
CCTCTTTGATTTTTAATCATTATG

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AOH59193.1\|290031_290298_-\|cell-division-protein-ZapA	unknown	unknown	gnl\|CDD\|172616
CP016856.2\|AOH59759.1\|287724_289437_-\|DNA-polymerase/3'-5'-exonuclease-PolX	unknown	unknown	gnl\|CDD\|236311
CP016856.2\|AOH57487.1\|298142_299111_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682
CP016856.2\|AUN01072.1\|284721_284817_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH57724.1\|280018_281785_-\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|236319
CP016856.2\|AOH59088.1\|279203_280019_-\|succinate-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|181515
CP016856.2\|AUN01076.1\|296860_296968_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01074.1\|289509_290031_-\|colicin-V-production-protein-CvpA	unknown	unknown	gnl\|CDD\|224205
CP016856.2\|AOH58924.1\|292040_294443_-\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
CP016856.2\|AOH59216.1\|299995_301072_-\|heme-ABC-transporter-permease	unknown	unknown	unknown
CP016856.2\|AOH59838.1\|294442_295501_-\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
CP016856.2\|AUN01075.1\|291860_291989_-\|acyltransferase	unknown	unknown	unknown
CP016856.2\|AOH58855.1\|284879_285194_-\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|200072
CP016856.2\|AOH60164.1\|282774_284556_-\|excinuclease-ABC-subunit-C	unknown	unknown	gnl\|CDD\|234792
CP016856.2\|AUN01073.1\|285366_287715_-\|endonuclease-MutS2	unknown	unknown	gnl\|CDD\|234750
CP016856.2\|AOH57977.2\|299120_299999_-\|heme-uptake-system-protein-IsdE	unknown	unknown	gnl\|CDD\|274706
CP016856.2\|AOH58871.1\|297346_298081_-\|SrtB-family-sortase	unknown	unknown	gnl\|CDD\|226898
CP016856.2\|AOH59252.1\|297004_297328_-\|staphylobilin-forming-heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|139480
CP016856.2\|AOH59454.1\|281836_282451_-\|succinate-dehydrogenase	unknown	unknown	gnl\|CDD\|239577
CP016856.2\|AOH60085.1\|295880_296621_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH59193.1\|290031_290298_-\|cell-division-protein-ZapA	gnl\|CDD\|172616	PRK14126, PRK14126, cell division protein ZapA; Provisional.	1.04877e-21
CP016856.2\|AOH59759.1\|287724_289437_-\|DNA-polymerase/3'-5'-exonuclease-PolX	gnl\|CDD\|236311	PRK08609, PRK08609, DNA polymerase/3'-5' exonuclease PolX.	0
CP016856.2\|AOH57487.1\|298142_299111_-\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	1.25627e-60
CP016856.2\|AOH60085.1\|295880_296621_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.00285e-77
CP016856.2\|AOH57724.1\|280018_281785_-\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|236319	PRK08641, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
CP016856.2\|AOH59088.1\|279203_280019_-\|succinate-dehydrogenase-iron-sulfur-subunit	gnl\|CDD\|181515	PRK08640, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	0
CP016856.2\|AOH57977.2\|299120_299999_-\|heme-uptake-system-protein-IsdE	gnl\|CDD\|274706	TIGR03659, heme_ABC_transporter_heme-binding_protein_isdE, heme ABC transporter, heme-binding protein isdE. This family of ABC substrate-binding proteins is observed primarily in close proximity with proteins localized to the cell wall and bearing the NEAT (NEAr Transporter, pfam05031) heme-binding domain. IsdE has been shown to bind heme and is involved in the process of scavenging heme for the purpose of obtaining iron.	9.77537e-156
CP016856.2\|AUN01074.1\|289509_290031_-\|colicin-V-production-protein-CvpA	gnl\|CDD\|224205	COG1286, CvpA, Uncharacterized membrane protein, required for colicin V production [General function prediction only].	4.13485e-29
CP016856.2\|AOH58924.1\|292040_294443_-\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
CP016856.2\|AOH59838.1\|294442_295501_-\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
CP016856.2\|AOH58855.1\|284879_285194_-\|thiol-reductase-thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.26685e-48
CP016856.2\|AOH60164.1\|282774_284556_-\|excinuclease-ABC-subunit-C	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
CP016856.2\|AUN01073.1\|285366_287715_-\|endonuclease-MutS2	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
CP016856.2\|AOH58871.1\|297346_298081_-\|SrtB-family-sortase	gnl\|CDD\|226898	COG4509, COG4509, Uncharacterized protein conserved in bacteria [Function unknown].	2.78558e-128
CP016856.2\|AOH59252.1\|297004_297328_-\|staphylobilin-forming-heme-oxygenase-IsdG	gnl\|CDD\|139480	PRK13312, PRK13312, staphylobilin-forming heme oxygenase IsdG.	3.35893e-67
CP016856.2\|AOH59454.1\|281836_282451_-\|succinate-dehydrogenase	gnl\|CDD\|239577	cd03497, SQR_TypeB_1_TM, Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis SQR reduces low potential quinones such as menaquinone. SQR is also called succinate dehydrogenase (Sdh) or Complex II and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are classified as Type B as they contain one transmembrane subunit and two heme groups. The heme and quinone binding sites reside on the transmembrane subunit. The transmembrane subunit of Bacillus subtilis SQR is also called Sdh cytochrome b558 subunit. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centers, and the transmembrane subunit containing the electron acceptor (quinone). The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	2.37018e-87

>CP016856.2|AOH59193.1|290031_290298_-|cell-division-protein-ZapA
MAQFKNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKLQQREQ
>CP016856.2|AUN01074.1|289509_290031_-|colicin-V-production-protein-CvpA
MVIDFIIIIFFVYFVIVGFRRGFWLSMIHLSATIVSLWIASQFYKSIVERLIVFIPYPKTTAFNTTFAFHFNHLQNRFEAIVAFLMITLFCKFILYLIIVTFDKIIAYQNIHIFSRAMGMIVGVFMTIIVLHFTLYLLALYPNEALQHQLKISIVSHSLIFHIPYLSAFTINL
>CP016856.2|AOH59759.1|287724_289437_-|DNA-polymerase/3'-5'-exonuclease-PolX
MTKKDVIKLLEQIATYMELKEENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRLNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGVDFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDKDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEIDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIEQLMALAEETNTVLEINANPHRLDLNADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDFIENNIKLKK
>CP016856.2|AUN01073.1|285366_287715_-|endonuclease-MutS2
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
>CP016856.2|AOH58855.1|284879_285194_-|thiol-reductase-thioredoxin
MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
>CP016856.2|AUN01072.1|284721_284817_+|hypothetical-protein
MLDYHLTFIDLLIPPFSSRKQYDDLSFNFLY
>CP016856.2|AOH60164.1|282774_284556_-|excinuclease-ABC-subunit-C
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
>CP016856.2|AOH59454.1|281836_282451_-|succinate-dehydrogenase
MAQSKNEFYLRRIHSLLGIIPIGAFLVVHLLVNHQATQGAEAFNKASNFMESLPFLIIVEFLFIYIPLLYHGLFGIHIAFTAKENVGHYSIFRNWMFFFQRVSGILTFIFIGIHLWQTRLQKAFYGKEVNYDLMHETLQHPGWAIFYIICIIAVVFHFANGLWSFLVTWGGLQSPKSQRVFTWVSLIVFLVISYIGVTAIIAFM
>CP016856.2|AOH57724.1|280018_281785_-|succinate-dehydrogenase-flavoprotein-subunit
MAEKHLIVVGGGLAGLMSTIKAAEKGAHVDLFSVVPVKRSHSVCAQGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVMFNRTNEGLLDFRRFGGTLHHRTAYAGATTGQQLLYALDEQVRAFEVDGLVTKYEGWEFLGIVKGDDDSARGIVAQNMTTAEIETFGSDAVIMATGGPGIIFGKTTNSMINTGSAASIVYQQGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPDYGNLVPRDIATREIFDVCINQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFTGDDPRKVPMKIFPAVHYSMGGLYVDYDQMTNIKGLFAAGECDFSQHGGNRLGANSLLSAIYGGTVAGPNAIDYISNIDRSYTDMDESIFEKRKAEEQERFDKLLAMRGTENAYKLHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYEDIDMEDTQTWSNQAVFFTRQLWNMLVLARVITIGAYNRNESRGAHYKPEFPERNDEEWLKTTMASFQGAFEKPQFTYDDVDVSLIPPRKRDYTSKSKGGKK
>CP016856.2|AOH59088.1|279203_280019_-|succinate-dehydrogenase-iron-sulfur-subunit
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKKRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPKGIPLTTSIAAMNRETTFHMFKSFFGSDHEVE
>CP016856.2|AUN01075.1|291860_291989_-|acyltransferase
MGVYFWVHQLGSNAFKKSKRNSGIQMMLCTTAYKVILMSKAN
>CP016856.2|AOH58924.1|292040_294443_-|phenylalanine--tRNA-ligase-subunit-beta
MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNYIPKSFESGIYVFSEAQVPGTDALQALYLDDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPDTTSNELELSANNELTVTIENEDKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDGTERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVQVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFEKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYLAKGIVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLKRTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEHGAVIR
>CP016856.2|AOH59838.1|294442_295501_-|phenylalanine--tRNA-ligase-subunit-alpha
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
>CP016856.2|AOH60085.1|295880_296621_-|RNA-methyltransferase
MEQITSAQNNRIKQANKLKKKRERDKTGLALIEGVHLIEEAYQSGIVITQLFAIEPARLDQQIIAYAQEVFEINMKVAESLSGTVTPQGFFAIIEKPHYDISKAQQVLLIDRVQDPGNLGTLIRTADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLPVMIQDLDTFITQFNGPVYGTALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQNLIIPIYGKAESLNVAIAGSILLYHLKG
>CP016856.2|AUN01076.1|296860_296968_-|hypothetical-protein
MVLLAFVTTIHDTDDGRFFNEHKHANNKLLKHSLI
>CP016856.2|AOH59252.1|297004_297328_-|staphylobilin-forming-heme-oxygenase-IsdG
MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
>CP016856.2|AOH58871.1|297346_298081_-|SrtB-family-sortase
MRMKRFLTIVQILLVVIIIIFGYKIVQTYIEDKQERANYEKLQQKFQMLMSKHQAHVRPQFESLEKINKDIVGWIKLSGTSLNYPVLQGKTNHDYLNLDFEREHRRKGSIFMDFRNELKNLNHNTILYGHHVGDNTMFDVLEDYLKQSFYEKHKIIEFDNKYGKYQLQVFSAYKTTTKDNYIRTDFENDQDYQQFLDETKRKSVINSDVNVTVKDRIMTLSTCEDAYSETTKRIVVVAKIIKVS
>CP016856.2|AOH57487.1|298142_299111_-|iron-ABC-transporter-permease
MMIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLICLICQSQRNRI
>CP016856.2|AOH57977.2|299120_299999_-|heme-uptake-system-protein-IsdE
MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
>CP016856.2|AOH59216.1|299995_301072_-|heme-ABC-transporter-permease
MRNVKQIATKSIIAIISLGILTYTTMIGSVLADEIKYPSAKFNQPEAKDKTELTTSIFDEKIKENKALELLIFNQENKNVTEEQKLVDEKAQLISDMTGKIYLQVKLKGQIDKEQLVFQNDKNEEFPFVIKDEKDDTIVRILIEQHMDKINMHVKTLAEKKNLDNKEMVYSIHFKEKKVQHDDAKEVPSKHQNQENNQDQLKKDIDDKKDSQKSDTKERRTSLFTEKGLNDIPVQKDKVQQDSNKKIENERPKASGTLKVENSPPTIKKVENNHKEQPKHKDEKSKKEKKKVVEKEKALPAFNRDDDSKNSSQLSSDIKELDEPNHKKQYILFAAGIVLATILLISAHLYSRKRGNQV

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Crispr_ID: CP016856_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_2

500113-500191

Orphan

Consensus_repeat	Method
CCAGCCTCTGTGTTGGGGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP016856_2

>merge|CP016856|2|500113-500191|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCGCCAACTTGCACACTATTGTAAGCTGACTTTCCACCAGCCTCTGTGTTGGGGCCCCG

>CP016856|2|2|500113-500191|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCG	CCAACTTGCACACTATTGTAAGCTGACTTTCCA
CCAGCCTCTGTGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AOH59013.1\|504655_505033_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|224023
CP016856.2\|AOH59250.1\|488782_492259_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
CP016856.2\|AOH58830.1\|501668_502859_-\|Ornithine-aminotransferase-2	unknown	unknown	gnl\|CDD\|179736
CP016856.2\|AOH57566.1\|493009_493534_-\|inactive-signal-peptidase-IA	unknown	unknown	gnl\|CDD\|274044
CP016856.2\|AOH58390.1\|506104_506488_+\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|378054
CP016856.2\|AOH59452.1\|509778_511275_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP016856.2\|AOH58791.1\|485128_488782_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
CP016856.2\|AOH57654.1\|500315_501560_-\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP016856.2\|AOH60144.1\|484060_484963_-\|FAA-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP016856.2\|AOH58564.2\|509456_509786_+\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP016856.2\|AOH58040.1\|493538_494114_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP016856.2\|AOH57631.1\|494438_495770_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP016856.2\|AOH58603.2\|506618_509024_+\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
CP016856.2\|AOH59913.1\|492418_492994_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP016856.2\|AOH57511.1\|509016_509445_+\|Na+/H+-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP016856.2\|AOH60114.1\|496119_497325_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP016856.2\|AOH58177.1\|497314_498694_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP016856.2\|AOH59565.2\|503166_504294_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
CP016856.2\|AOH59545.1\|498935_499865_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
CP016856.2\|AOH58660.1\|505447_506041_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH59013.1\|504655_505033_-\|general-stress-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP016856.2\|AOH59250.1\|488782_492259_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP016856.2\|AOH58830.1\|501668_502859_-\|Ornithine-aminotransferase-2	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP016856.2\|AOH57566.1\|493009_493534_-\|inactive-signal-peptidase-IA	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	9.64837e-49
CP016856.2\|AOH58390.1\|506104_506488_+\|adenosine-deaminase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP016856.2\|AOH59452.1\|509778_511275_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP016856.2\|AOH58791.1\|485128_488782_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP016856.2\|AOH57654.1\|500315_501560_-\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP016856.2\|AOH60144.1\|484060_484963_-\|FAA-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
CP016856.2\|AOH58564.2\|509456_509786_+\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
CP016856.2\|AOH58040.1\|493538_494114_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP016856.2\|AOH57631.1\|494438_495770_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP016856.2\|AOH58603.2\|506618_509024_+\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP016856.2\|AOH59913.1\|492418_492994_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	3.65162e-54
CP016856.2\|AOH57511.1\|509016_509445_+\|Na+/H+-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP016856.2\|AOH60114.1\|496119_497325_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP016856.2\|AOH58177.1\|497314_498694_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP016856.2\|AOH59565.2\|503166_504294_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP016856.2\|AOH59545.1\|498935_499865_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP016856.2\|AOH58660.1\|505447_506041_-\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65

>CP016856.2|AOH59545.1|498935_499865_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP016856.2|AOH58177.1|497314_498694_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP016856.2|AOH60114.1|496119_497325_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP016856.2|AOH57631.1|494438_495770_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP016856.2|AOH58040.1|493538_494114_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP016856.2|AOH57566.1|493009_493534_-|inactive-signal-peptidase-IA
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPSLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP016856.2|AOH59913.1|492418_492994_-|signal-peptidase-I
MKKELLEWIISIAIALVIFAIIGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP016856.2|AOH59250.1|488782_492259_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTETKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKIEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDETMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP016856.2|AOH58791.1|485128_488782_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTDHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQAHNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP016856.2|AOH60144.1|484060_484963_-|FAA-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>CP016856.2|AOH57654.1|500315_501560_-|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP016856.2|AOH58830.1|501668_502859_-|Ornithine-aminotransferase-2
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP016856.2|AOH59565.2|503166_504294_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPGGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWVNQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP016856.2|AOH59013.1|504655_505033_-|general-stress-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP016856.2|AOH58660.1|505447_506041_-|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP016856.2|AOH58390.1|506104_506488_+|adenosine-deaminase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP016856.2|AOH58603.2|506618_509024_+|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFISTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP016856.2|AOH57511.1|509016_509445_+|Na+/H+-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP016856.2|AOH58564.2|509456_509786_+|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP016856.2|AOH59452.1|509778_511275_+|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Crispr_ID: CP016856_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_3

596515-596592

Unclear

Consensus_repeat	Method
TGGCGGGGCCCCAACATAAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP016856_3

>merge|CP016856|3|596515-596592|CRISPRCasFinder
TGGCGGGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACATAAAGAA

>CP016856|3|3|596515-596592|CRISPRCasFinder
TGGCGGGGCCCCAACATAAAGAA	TTTCGAAAAGAAATTCTACAAACAATGCAAGT
TGGCGGGGCCCCAACATAAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AOH58373.1\|588769_589765_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
CP016856.2\|AOH57935.1\|596880_599727_-\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP016856.2\|AOH59482.1\|608663_609236_-\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP016856.2\|AOH57951.1\|586563_587151_-\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
CP016856.2\|AOH58767.1\|592557_593997_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
CP016856.2\|AOH58574.1\|599734_601720_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
CP016856.2\|AOH59948.2\|604293_605404_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP016856.2\|AOH59729.1\|602221_602872_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
CP016856.2\|AUN01102.1\|604032_604140_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01103.1\|605572_605677_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH59150.1\|589761_590673_-\|RNase-adaptor-protein-RapZ	unknown	unknown	gnl\|CDD\|224574
CP016856.2\|AOH59023.1\|594497_595337_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP016856.2\|AOH59404.1\|605718_608250_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
CP016856.2\|AUN01101.1\|594004_594490_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
CP016856.2\|AOH57649.1\|591555_592491_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP016856.2\|AOH59640.1\|603045_603885_-\|peptidase-M23	unknown	unknown	gnl\|CDD\|226451
CP016856.2\|AOH59442.1\|601988_602225_-\|DUF2198-domain-containing-protein	unknown	unknown	gnl\|CDD\|227234
CP016856.2\|AOH58181.1\|587714_588659_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
CP016856.2\|AOH59347.1\|595342_596275_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
CP016856.2\|AUN01375.1\|590873_591236_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH58373.1\|588769_589765_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP016856.2\|AOH57935.1\|596880_599727_-\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP016856.2\|AOH59482.1\|608663_609236_-\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP016856.2\|AOH57951.1\|586563_587151_-\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP016856.2\|AOH58767.1\|592557_593997_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP016856.2\|AOH58574.1\|599734_601720_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP016856.2\|AOH59948.2\|604293_605404_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP016856.2\|AOH59729.1\|602221_602872_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP016856.2\|AOH59150.1\|589761_590673_-\|RNase-adaptor-protein-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP016856.2\|AOH59023.1\|594497_595337_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.81145e-120
CP016856.2\|AOH59404.1\|605718_608250_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP016856.2\|AUN01101.1\|594004_594490_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	5.56005e-29
CP016856.2\|AOH57649.1\|591555_592491_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	5.91243e-154
CP016856.2\|AOH59640.1\|603045_603885_-\|peptidase-M23	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
CP016856.2\|AOH59442.1\|601988_602225_-\|DUF2198-domain-containing-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP016856.2\|AOH58181.1\|587714_588659_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP016856.2\|AOH59347.1\|595342_596275_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170

>CP016856.2|AOH59347.1|595342_596275_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP016856.2|AOH59023.1|594497_595337_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP016856.2|AUN01101.1|594004_594490_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLVGANSIILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP016856.2|AOH58767.1|592557_593997_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP016856.2|AOH57649.1|591555_592491_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLKDQA
>CP016856.2|AUN01375.1|590873_591236_+|hypothetical-protein
MRLQQAFFNSSQEPQHREIGFPISTDNASWGVGPNTENFEKKFYRQCKLGCGPQHREFRKEILQAMRVGVWAPTQKLTKSQLTIMCKLAGPQQREIGFPISTDSASWGGTTIKKYFFYRN
>CP016856.2|AOH59150.1|589761_590673_-|RNase-adaptor-protein-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP016856.2|AOH58373.1|588769_589765_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP016856.2|AOH58181.1|587714_588659_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP016856.2|AOH57951.1|586563_587151_-|ATP-dependent-Clp-protease-proteolytic-subunit
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP016856.2|AOH57935.1|596880_599727_-|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP016856.2|AOH58574.1|599734_601720_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYRTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP016856.2|AOH59442.1|601988_602225_-|DUF2198-domain-containing-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP016856.2|AOH59729.1|602221_602872_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP016856.2|AOH59640.1|603045_603885_-|peptidase-M23
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP016856.2|AUN01102.1|604032_604140_-|hypothetical-protein
MYLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>CP016856.2|AOH59948.2|604293_605404_-|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP016856.2|AUN01103.1|605572_605677_-|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>CP016856.2|AOH59404.1|605718_608250_-|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP016856.2|AOH59482.1|608663_609236_-|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ

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Crispr_ID: CP016856_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_4

1009824-1009926

Orphan

Consensus_repeat	Method
CAAATTTAATACTCAATTCATATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP016856_4

>merge|CP016856|4|1009824-1009926|CRISPRCasFinder
CAAATTTAATACTCAATTCATATATAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTTCAAATTTAATACTCAATTCATAAA

>CP016856|4|4|1009824-1009926|CRISPRCasFinder
CAAATTTAATACTCAATTCATATA	TAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTT
CAAATTTAATACTCAATTCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AOH60206.1\|1005161_1006430_-\|purine-permease	unknown	unknown	gnl\|CDD\|274468
CP016856.2\|AOH59292.1\|1014084_1015608_+\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP016856.2\|AOH58128.1\|1018296_1018680_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH57555.1\|1010784_1012173_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
CP016856.2\|AOH59401.1\|999286_999679_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01152.1\|1010601_1010700_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01150.1\|1000473_1001580_-\|CAAX-protease	unknown	unknown	gnl\|CDD\|377910
CP016856.2\|AOH58042.1\|1008850_1009807_+\|cell-envelope-integrity-protein-TolA	unknown	unknown	gnl\|CDD\|274008
CP016856.2\|AOH59710.1\|1012252_1013008_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP016856.2\|AUN01149.1\|999844_1000027_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH57852.1\|1018745_1019327_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP016856.2\|AOH57506.1\|1008070_1008733_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH57653.2\|1017414_1018041_+\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
CP016856.2\|AUN01151.1\|1010133_1010391_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01381.1\|1017063_1017342_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH59463.1\|1003657_1005124_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP016856.2\|AOH58861.1\|1002091_1003633_-\|GMP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|234614
CP016856.2\|AOH60200.1\|1007520_1007928_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP016856.2\|AOH59324.1\|1013499_1014069_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP016856.2\|AOH59794.1\|1006429_1007008_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH60206.1\|1005161_1006430_-\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.28569e-170
CP016856.2\|AOH59292.1\|1014084_1015608_+\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP016856.2\|AOH57555.1\|1010784_1012173_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP016856.2\|AOH59794.1\|1006429_1007008_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP016856.2\|AOH58042.1\|1008850_1009807_+\|cell-envelope-integrity-protein-TolA	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00304381
CP016856.2\|AOH59710.1\|1012252_1013008_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
CP016856.2\|AUN01150.1\|1000473_1001580_-\|CAAX-protease	gnl\|CDD\|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	2.0112e-23
CP016856.2\|AOH57852.1\|1018745_1019327_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.30018e-49
CP016856.2\|AOH57653.2\|1017414_1018041_+\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
CP016856.2\|AOH58861.1\|1002091_1003633_-\|GMP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP016856.2\|AOH59463.1\|1003657_1005124_-\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP016856.2\|AOH60200.1\|1007520_1007928_+\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
CP016856.2\|AOH59324.1\|1013499_1014069_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124

>CP016856.2|AOH58042.1|1008850_1009807_+|cell-envelope-integrity-protein-TolA
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLFGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVTTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP016856.2|AOH57506.1|1008070_1008733_+|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP016856.2|AOH60200.1|1007520_1007928_+|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>CP016856.2|AOH59794.1|1006429_1007008_-|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP016856.2|AOH60206.1|1005161_1006430_-|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLIICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP016856.2|AOH59463.1|1003657_1005124_-|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP016856.2|AOH58861.1|1002091_1003633_-|GMP-synthase-(glutamine-hydrolyzing)
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP016856.2|AUN01150.1|1000473_1001580_-|CAAX-protease
MDKSLEINLKELESIMYKEKVIDVKEYDNLKVTFETLNDAPKSEIPTPFTIEQMLYKLETKNLYFPEIKSKEKCVELLHSVGYYNLKHFMYNEFGKDEPKNFDEVYILYKFDRYLLKQLFSLVNMLETHIRNIILEVYMLEIEYNNKPSTLFYLDKDLYFEKVNDEYKYSAKKLKEFNRLQNVFWRAIEKKKSNDNVKHNIKKYNIIPAWVLFQNFSFGDLSTFYRTTLPTYRNKVSKRIENLIEKNTGISIKLPEKLLCAWLNSIRFLRNRIAHTDIIYGINFTNTCAKHHSDEEMYVNIEKYKYQQRLVTFLLAMKKIFMSMPENNIIEWNETLTKIENKCSEHNFIKLSRLGVIENNLSYFKITK
>CP016856.2|AUN01149.1|999844_1000027_-|hypothetical-protein
MFLIWATSCYEMIGVIYVEIGVPISLCWGPAVNYCQYKIVEPTILILCPRLGFLRLVKYL
>CP016856.2|AOH59401.1|999286_999679_+|hypothetical-protein
MLEDNGDIRLLYQSIEELASVLGQSQFETKTVSLIFVQMDLRYSVFEKVQTDFMKYLAHKNSDEIKYIDLIKIIENALPEDKELSINVINSIIIGFANNYYPILQSLVPEIQSSYGITINKNFNIDSIDF
>CP016856.2|AUN01151.1|1010133_1010391_+|hypothetical-protein
MLVTDESHKCTLIFTFTTNAFLLKQKYLFTVAFELPPAHTNTQKMLILIRQNFLQRVCSKRLFKVDHLLSFHSINMRLAIFIKPP
>CP016856.2|AUN01152.1|1010601_1010700_-|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>CP016856.2|AOH57555.1|1010784_1012173_+|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKSAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLVILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>CP016856.2|AOH59710.1|1012252_1013008_-|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP016856.2|AOH59324.1|1013499_1014069_+|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP016856.2|AOH59292.1|1014084_1015608_+|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP016856.2|AUN01381.1|1017063_1017342_+|hypothetical-protein
MKSDQAIKEFTSYLRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLIQPIMQLFIDNAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP016856.2|AOH57653.2|1017414_1018041_+|NDxxF-motif-lipoprotein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP016856.2|AOH58128.1|1018296_1018680_+|hypothetical-protein
MKVRITFIILSILSTIVCLFLAAMHPTGPSTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVDKNDSH
>CP016856.2|AOH57852.1|1018745_1019327_-|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQQDDIVIVAHQVVIRCLMVYFNNVSREEAVDLKVENCKPYIIE

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Crispr_ID: CP016856_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_6

1707303-1707400

Orphan

Consensus_repeat	Method
GCCTTTCTAGCTCATAAAATTCGCAGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP016856_6

>merge|CP016856|6|1707303-1707400|CRISPRCasFinder
GCCTTTCTAGCTCATAAAATTCGCAGAAAATAAAGGAACGCATTAGATAGCTTCGCTACTAATGCATAAGCCTTTCTAGCTCATAAAATTCGCAGAAA

>CP016856|6|5|1707303-1707400|CRISPRCasFinder
GCCTTTCTAGCTCATAAAATTCGCAGAAA	ATAAAGGAACGCATTAGATAGCTTCGCTACTAATGCATAA
GCCTTTCTAGCTCATAAAATTCGCAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AUN01235.1\|1705076_1705259_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH58231.1\|1712886_1713618_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
CP016856.2\|AOH57568.2\|1709886_1711290_+\|methyl-viologen-resistance-protein-SmvA	unknown	unknown	gnl\|CDD\|129794
CP016856.2\|AOH59026.1\|1707539_1708406_+\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
CP016856.2\|AOH59756.2\|1704012_1704942_-\|bi-component-gamma-hemolysin-HlgAB-subunit-A	unknown	unknown	gnl\|CDD\|369625
CP016856.2\|AOH60160.2\|1702498_1703446_-\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625
CP016856.2\|AOH59696.1\|1715219_1715582_+\|cystatin-like-fold-lipoprotein	unknown	unknown	gnl\|CDD\|291399
CP016856.2\|AOH59053.1\|1708732_1709419_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
CP016856.2\|AOH59804.1\|1701000_1701468_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
CP016856.2\|AOH59762.1\|1700297_1700990_+\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
CP016856.2\|AOH59085.1\|1711410_1712190_+\|glutamine-ABC-transporter-substrate-binding-protein-GlnH	unknown	unknown	gnl\|CDD\|270429
CP016856.2\|AOH59520.1\|1701519_1702497_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
CP016856.2\|AUN01238.1\|1706881_1706986_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH59854.1\|1713714_1714965_-\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
CP016856.2\|AUN01389.1\|1709801_1709921_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH58296.2\|1699171_1700287_+\|glycine-C-acetyltransferase	unknown	unknown	gnl\|CDD\|223234
CP016856.2\|AUN01236.1\|1705387_1705573_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH57676.1\|1712170_1712890_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
CP016856.2\|AUN01237.1\|1705476_1706787_-\|immunoglobulin-binding-protein-sbi	unknown	unknown	gnl\|CDD\|288473
CP016856.2\|AUN01239.1\|1709572_1709677_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH58231.1\|1712886_1713618_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.20826e-144
CP016856.2\|AOH57568.2\|1709886_1711290_+\|methyl-viologen-resistance-protein-SmvA	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.06541e-91
CP016856.2\|AOH59026.1\|1707539_1708406_+\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.54055e-90
CP016856.2\|AOH59756.2\|1704012_1704942_-\|bi-component-gamma-hemolysin-HlgAB-subunit-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	4.31899e-97
CP016856.2\|AOH60160.2\|1702498_1703446_-\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	7.97441e-93
CP016856.2\|AOH59696.1\|1715219_1715582_+\|cystatin-like-fold-lipoprotein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	3.11961e-31
CP016856.2\|AOH59804.1\|1701000_1701468_+\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00158559
CP016856.2\|AOH59762.1\|1700297_1700990_+\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	2.9803e-130
CP016856.2\|AOH59520.1\|1701519_1702497_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
CP016856.2\|AOH59053.1\|1708732_1709419_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
CP016856.2\|AOH59854.1\|1713714_1714965_-\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
CP016856.2\|AOH58296.2\|1699171_1700287_+\|glycine-C-acetyltransferase	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	1.99808e-138
CP016856.2\|AOH57676.1\|1712170_1712890_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.98247e-78
CP016856.2\|AUN01237.1\|1705476_1706787_-\|immunoglobulin-binding-protein-sbi	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	1.70632e-25
CP016856.2\|AOH59085.1\|1711410_1712190_+\|glutamine-ABC-transporter-substrate-binding-protein-GlnH	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.11829e-100

>CP016856.2|AUN01238.1|1706881_1706986_+|hypothetical-protein
MLTNRLTSVNYVKKRLIQNIQRILSKEVLYGEMQ
>CP016856.2|AUN01237.1|1705476_1706787_-|immunoglobulin-binding-protein-sbi
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDKSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAITKLQKNDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVTETLNTGKVLYAFYQNPKVVKAAITTAETASSIKNTLSNLLSFWK
>CP016856.2|AUN01236.1|1705387_1705573_+|hypothetical-protein
MENQRFFLITVYYENYLKNDVKLEKILLIDYFQNDNKLLNVFLIDDAVSAVVIAALTTFGF
>CP016856.2|AUN01235.1|1705076_1705259_+|hypothetical-protein
MMFLHYVMFKRFIGRRRLYSYITMFCKSYSIELLFNYGACSGRGMDCAIVCENLKLIKLS
>CP016856.2|AOH59756.2|1704012_1704942_-|bi-component-gamma-hemolysin-HlgAB-subunit-A
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>CP016856.2|AOH60160.2|1702498_1703446_-|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
>CP016856.2|AOH59520.1|1701519_1702497_-|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>CP016856.2|AOH59804.1|1701000_1701468_+|hypothetical-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTMRKRMAVLLR
>CP016856.2|AOH59762.1|1700297_1700990_+|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDNRIDLNHYISFLESTPKQVVYETV
>CP016856.2|AOH58296.2|1699171_1700287_+|glycine-C-acetyltransferase
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAEYPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGIDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>CP016856.2|AOH59026.1|1707539_1708406_+|cation-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>CP016856.2|AOH59053.1|1708732_1709419_+|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>CP016856.2|AUN01239.1|1709572_1709677_-|hypothetical-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>CP016856.2|AUN01389.1|1709801_1709921_+|hypothetical-protein
MSKNECCFLDGEGEALNVEETKINDDYYYADGWIFWIIK
>CP016856.2|AOH57568.2|1709886_1711290_+|methyl-viologen-resistance-protein-SmvA
MLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAGFLFALLITVVSFFCSFMLQGKKKEVDSRQ
>CP016856.2|AOH59085.1|1711410_1712190_+|glutamine-ABC-transporter-substrate-binding-protein-GlnH
MKRLLFVMIAFVFILAACGNNSSKDKEANKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAFSKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>CP016856.2|AOH57676.1|1712170_1712890_+|amino-acid-ABC-transporter-permease
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>CP016856.2|AOH58231.1|1712886_1713618_+|amino-acid-ABC-transporter-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE
>CP016856.2|AOH59854.1|1713714_1714965_-|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALKESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPMFYKIQQYLNHKRR
>CP016856.2|AOH59696.1|1715219_1715582_+|cystatin-like-fold-lipoprotein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDSRRYYQQHDADYHEENMTN

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Crispr_ID: CP016856_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP016856_7

2213853-2213984

Orphan

Consensus_repeat	Method
CAGGTTGGCGGGGCCCCAACAAAGAGAA	PILER-CR
CAGGTTGGCGGGGCCCCAACACAGA	CRISPRCasFinder

2 spacers

DEDDh

The CRISPR arrays of CP016856_7

>merge|CP016856|7|2213853-2213984|PILER-CR,CRISPRCasFinder
CGGGGCCCCAACAAAGAGAATTTCAAAAAAGAAATTCTACAGGCAATACAGGTTGGCGGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACGATAATGTGCAGGTTGGCGGGGCCCCAACATAGAGAA

>CP016856|7|2|2213853-2213984|PILER-CR
CGGGGCCCCAACAAAGAGAATTTCAAAA	AAGAAATTCTACAGGCAATACAGGTTGG
CGGGGCCCCAACACAGAAGCTGACGAAA	AGTCAGCTTACGATAATGTGCAGGTTGGCGG
GGCCCCAACATAGAGAA

>CP016856|7|6|2213901-2213981|CRISPRCasFinder
CAGGTTGGCGGGGCCCCAACACAGA	AGCTGACGAAAAGTCAGCTTACGATAATGTG
CAGGTTGGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP016856.2\|AOH59373.1\|2212645_2213632_-\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
CP016856.2\|AUN01300.1\|2205880_2206411_+\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
CP016856.2\|AOH57779.2\|2211801_2212215_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH59882.1\|2214159_2214918_+\|methionine-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
CP016856.2\|AOH58321.1\|2206657_2207728_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
CP016856.2\|AOH58131.1\|2219784_2220249_-\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319971
CP016856.2\|AOH58171.1\|2217266_2217896_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|225107
CP016856.2\|AOH59227.1\|2220395_2220596_+\|DUF1128-domain-containing-protein	unknown	unknown	gnl\|CDD\|227177
CP016856.2\|AOH57877.1\|2209530_2210844_+\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
CP016856.2\|AOH57793.1\|2208738_2209239_-\|non-heme-ferritin	unknown	unknown	gnl\|CDD\|224445
CP016856.2\|AOH58208.1\|2210845_2211577_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
CP016856.2\|AUN01302.1\|2211662_2211773_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01301.1\|2208564_2208657_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AUN01303.1\|2215535_2216237_+\|transporter	unknown	unknown	gnl\|CDD\|227100
CP016856.2\|AOH58992.1\|2215134_2215521_+\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH58216.1\|2218007_2219225_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
CP016856.2\|AOH59120.1\|2219502_2219778_-\|hypothetical-protein	unknown	unknown	unknown
CP016856.2\|AOH58592.1\|2207794_2208349_-\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP016856.2\|AOH59341.1\|2216233_2217277_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
CP016856.2\|AOH59550.2\|2220598_2221855_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723

Protein	Function_ID	Function_description	E-value
CP016856.2\|AOH59373.1\|2212645_2213632_-\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	5.31001e-76
CP016856.2\|AUN01300.1\|2205880_2206411_+\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
CP016856.2\|AOH59882.1\|2214159_2214918_+\|methionine-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP016856.2\|AOH58321.1\|2206657_2207728_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP016856.2\|AOH58131.1\|2219784_2220249_-\|protein-tyrosine-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP016856.2\|AOH59550.2\|2220598_2221855_+\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP016856.2\|AOH59227.1\|2220395_2220596_+\|DUF1128-domain-containing-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
CP016856.2\|AOH57877.1\|2209530_2210844_+\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
CP016856.2\|AOH57793.1\|2208738_2209239_-\|non-heme-ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP016856.2\|AOH58208.1\|2210845_2211577_+\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	2.14444e-120
CP016856.2\|AOH58171.1\|2217266_2217896_+\|DNA-binding-response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
CP016856.2\|AUN01303.1\|2215535_2216237_+\|transporter	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP016856.2\|AOH58216.1\|2218007_2219225_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	3.59491e-85
CP016856.2\|AOH58592.1\|2207794_2208349_-\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP016856.2\|AOH59341.1\|2216233_2217277_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72

>CP016856.2|AOH59373.1|2212645_2213632_-|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHLLYEVLMIYRLLDSRYA
>CP016856.2|AOH57779.2|2211801_2212215_+|hypothetical-protein
MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLY
>CP016856.2|AUN01302.1|2211662_2211773_+|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>CP016856.2|AOH58208.1|2210845_2211577_+|glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIIIESDTFGTIVGFENHGGRTFHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP016856.2|AOH57877.1|2209530_2210844_+|DUF1727-domain-containing-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP016856.2|AOH57793.1|2208738_2209239_-|non-heme-ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP016856.2|AUN01301.1|2208564_2208657_+|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>CP016856.2|AOH58592.1|2207794_2208349_-|DNA-polymerase-III-subunit-epsilon
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP016856.2|AOH58321.1|2206657_2207728_+|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVYSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEKTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGEFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP016856.2|AUN01300.1|2205880_2206411_+|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP016856.2|AOH59882.1|2214159_2214918_+|methionine-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP016856.2|AOH58992.1|2215134_2215521_+|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP016856.2|AUN01303.1|2215535_2216237_+|transporter
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP016856.2|AOH59341.1|2216233_2217277_+|two-component-sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP016856.2|AOH58171.1|2217266_2217896_+|DNA-binding-response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP016856.2|AOH58216.1|2218007_2219225_-|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP016856.2|AOH59120.1|2219502_2219778_-|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP016856.2|AOH58131.1|2219784_2220249_-|protein-tyrosine-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP016856.2|AOH59227.1|2220395_2220596_+|DUF1128-domain-containing-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>CP016856.2|AOH59550.2|2220598_2221855_+|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	1049770-1049801	1	0.969
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	1049825-1049856	1	0.969
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	2364279-2364310	1	0.969
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	59250-59280	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	268831-268861	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	369289-369319	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	761326-761356	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	1049943-1049973	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	1586320-1586350	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	1868269-1868299	1	0.968
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	2540276-2540306	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	59250-59280	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	268831-268861	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	369289-369319	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	761326-761356	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	1049943-1049973	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	1586320-1586350	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	1868269-1868299	1	0.968
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	2540276-2540306	1	0.968
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	590987-591018	2	0.938
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	761380-761411	2	0.938
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	1253897-1253928	2	0.938
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	1535798-1535829	2	0.938
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	1857411-1857442	2	0.938
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	CP016856.2	2203182-2203213	2	0.938
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	591100-591130	2	0.935
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	CP016856.2	1857352-1857382	2	0.935
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	591100-591130	2	0.935
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	CP016856.2	1857352-1857382	2	0.935

1. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 1049770-1049801, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaagcaatgcaagt	Protospacer
*********************.**********

2. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 1049825-1049856, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaagcaatgcaagt	Protospacer
*********************.**********

3. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 2364279-2364310, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacagacaatgcaagt	Protospacer
********************.***********

4. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 59250-59280, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

5. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 268831-268861, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

6. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 369289-369319, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

7. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 761326-761356, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

8. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 1049943-1049973, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

9. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 1586320-1586350, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

10. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 1868269-1868299, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

11. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 2540276-2540306, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

12. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 59250-59280, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

13. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 268831-268861, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

14. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 369289-369319, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

15. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 761326-761356, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

16. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 1049943-1049973, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

17. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 1586320-1586350, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

18. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 1868269-1868299, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

19. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 2540276-2540306, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

20. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 590987-591018, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

21. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 761380-761411, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

22. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 1253897-1253928, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

23. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 1535798-1535829, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

24. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 1857411-1857442, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcaaaaagaaattctacagacaatgcaagt	Protospacer
****.***************.***********

25. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to position: 2203182-2203213, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaggaaattctacagacaatgcaagt	Protospacer
********.***********.***********

26. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 591100-591130, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agcttacgaaaagtcagcttacaataatgtg	Protospacer
**** *****************.********

27. spacer 7.2|2213937|31|CP016856|PILER-CR matches to position: 1857352-1857382, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcatacaataatgtg	Protospacer
****************** ***.********

28. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 591100-591130, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agcttacgaaaagtcagcttacaataatgtg	Protospacer
**** *****************.********

29. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to position: 1857352-1857382, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcatacaataatgtg	Protospacer
****************** ***.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159749-159779	8	0.742
CP016856_7	7.2\|2213937\|31\|CP016856\|PILER-CR	2213937-2213967	31	LN846932	Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome	10622-10652	8	0.742
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159749-159779	8	0.742
CP016856_7	7.3\|2213926\|31\|CP016856\|CRISPRCasFinder	2213926-2213956	31	LN846932	Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome	10622-10652	8	0.742
CP016856_3	3.1\|596538\|32\|CP016856\|CRISPRCasFinder	596538-596569	32	MN693281	Marine virus AFVG_25M371, complete genome	6448-6479	9	0.719

1. spacer 7.2|2213937|31|CP016856|PILER-CR matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
gcttgacgaaaactcaccttacgataaaatt	Protospacer
. .********* *** ********** .*

2. spacer 7.2|2213937|31|CP016856|PILER-CR matches to LN846932 (Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
tgaagacgaaaaatcagattacgataaatta	Protospacer
 *  ********.**** *********  *.

3. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
gcttgacgaaaactcaccttacgataaaatt	Protospacer
. .********* *** ********** .*

4. spacer 7.3|2213926|31|CP016856|CRISPRCasFinder matches to LN846932 (Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
tgaagacgaaaaatcagattacgataaatta	Protospacer
 *  ********.**** *********  *.

5. spacer 3.1|596538|32|CP016856|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 9, identity: 0.719

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
cacttagaagaaatcctacaaacaatgcaaaa	Protospacer
. .. *.*******.***************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

359419 : 367892

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUN01083.1\|359419_359986_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1
AOH58153.1\|359988_361017_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AOH57795.1\|361009_362494_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-45	31.5
AOH59037.1\|362472_364662_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-140	39.7
AOH58646.1\|364654_365326_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AOH58915.1\|365327_365591_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AOH58989.1\|365590_366295_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AOH57921.1\|366298_367423_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AOH58136.1\|367409_367892_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_2

624944 : 639298

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH58076.2\|624944_625706_-	iron ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6
AOH57699.1\|625702_626659_-	iron ABC transporter permease	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AOH57848.1\|626645_627617_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AUN01107.1\|627655_627811_-	hypothetical protein	NA	NA	NA	NA
AOH58877.1\|627991_628963_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AOH59438.1\|629080_631186_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AOH58515.1\|631148_631547_-	protein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AOH58138.1\|632360_633227_+	EamA/RhaT family transporter	NA	NA	NA	NA
AOH59386.1\|633246_633747_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AUN01108.1\|633776_634022_+	hypothetical protein	NA	NA	NA	NA
AOH58477.1\|634087_635593_+	dipeptide/tripeptide permease DtpA	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AUN01109.1\|635670_635772_-	hypothetical protein	NA	NA	NA	NA
AOH57645.1\|635861_636779_+	lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
AUN01110.1\|637191_637290_-	hypothetical protein	NA	NA	NA	NA
AOH58700.1\|637402_637945_-	5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AOH59636.1\|638239_639298_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7

DBSCAN-SWA_3

651269 : 659089

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH57479.2\|651269_652421_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	7.8e-23	35.7
AOH59221.1\|652404_652998_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AOH58242.1\|653348_654017_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AOH58295.1\|654018_654438_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
AOH58335.1\|654441_655155_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AOH57697.1\|655253_655838_+	hypothetical protein	NA	NA	NA	NA
AOH57621.1\|656117_656558_+	hypothetical protein	NA	NA	NA	NA
AOH57669.1\|656899_657373_+	DoxX family protein	NA	NA	NA	NA
AOH60217.1\|657347_658034_+	DNA-binding response regulator	NA	NA	NA	NA
AOH58542.1\|658033_659089_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

DBSCAN-SWA_4

2106033 : 2169876

Staphylococcus_phage(95.71%)

integrase,tail,head,portal,capsid,terminase,holin,transposase,protease

attL 2108030:2108047|attR 2131006:2131023

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH58334.2\|2106033_2107086_+	bi-component leukocidin LukGH subunit H	A0A2I6PER8	Staphylococcus_phage	2.4e-34	31.8
AOH59217.1\|2107107_2108124_+	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	5.1e-26	29.3
2108030:2108047	attL	NA	NA	NA	NA
AUN01285.1\|2108361_2109186_-	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
AOH58293.1\|2109242_2110280_-\|integrase	site-specific integrase	A0EWV2	Staphylococcus_phage	9.1e-180	100.0
AOH59307.1\|2110338_2110803_-	murein hydrolase activator NlpD	A0EWV3	Staphylococcus_phage	1.1e-28	100.0
AOH59798.1\|2110902_2111085_-	hypothetical protein	M9NSW6	Staphylococcus_phage	4.1e-27	100.0
AOH59371.1\|2111288_2111630_-	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
AOH58785.1\|2111635_2112568_-	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AOH59267.1\|2112583_2113297_-	XRE family transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AUN01286.1\|2113259_2113433_+	transcriptional regulator	NA	NA	NA	NA
AOH59673.1\|2113429_2113693_+	XRE family transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	2.1e-40	98.9
AOH57763.1\|2113708_2113906_+	hypothetical protein	O80075	Staphylococcus_phage	3.5e-24	87.7
AOH60084.1\|2113892_2114273_-	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	3.4e-68	99.2
AOH58552.1\|2114327_2114651_+	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
AUN01287.1\|2114647_2114809_+	DUF1270 domain-containing protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
AOH57651.1\|2114903_2115206_+	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AOH60031.1\|2115210_2115471_+	DUF1108 domain-containing protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AUN01288.1\|2115479_2115743_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
AOH57808.2\|2115751_2117695_+	ATPase	S4V9K6	Staphylococcus_phage	0.0e+00	100.0
AOH57998.1\|2117696_2118617_+	recombinase	A0A2I6PDH5	Staphylococcus_phage	1.5e-165	99.7
AOH58884.2\|2118697_2119315_+	MBL fold metallo-hydrolase	A0A2I6PDI9	Staphylococcus_phage	9.1e-87	100.0
AOH60127.1\|2119315_2119786_+	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	1.3e-80	98.7
AOH57696.1\|2119815_2120709_+	DnaD domain protein	A0A2I6PDG7	Staphylococcus_phage	5.5e-141	99.3
AOH60181.1\|2120715_2120934_+	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
AOH59229.2\|2120942_2121347_+	RusA family crossover junction endodeoxyribonuclease	A0EWX6	Staphylococcus_phage	1.9e-72	100.0
AOH59889.1\|2121359_2121728_+	hypothetical protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
AOH59508.1\|2121731_2121974_+	hypothetical protein	Q4ZDP7	Staphylococcus_virus	2.1e-39	95.0
AOH60095.1\|2121988_2122243_+	DUF1024 domain-containing protein	A0A0H3U469	Staphylococcus_phage	5.0e-39	100.0
AOH58699.1\|2122392_2122929_+	dUTPase	A0A0H3U2Z8	Staphylococcus_phage	7.2e-96	100.0
AOH59323.1\|2122965_2123211_+	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
AOH59619.1\|2123207_2123414_+	succinate dehydrogenase flavoprotein subunit	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
AOH58481.1\|2123410_2123797_+	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
AOH57901.1\|2123793_2123943_+	transcriptional regulator	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AOH59866.1\|2123942_2124143_+	hypothetical protein	A0A2I6PDV9	Staphylococcus_phage	4.0e-28	98.5
AOH58460.1\|2124170_2124587_+	transcriptional regulator	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AOH57523.2\|2124818_2125118_+	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
AOH57811.1\|2125249_2125594_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AOH58598.2\|2125590_2127252_+\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	99.8
AOH59914.1\|2127267_2128455_+\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AOH59951.1\|2128438_2129176_+\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AOH58168.1\|2129199_2130345_+\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
AOH59039.1\|2130364_2130625_+	hypothetical protein	A0A0H3U504	Staphylococcus_phage	6.4e-42	100.0
AOH58214.1\|2130637_2130922_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AOH58004.1\|2130905_2131268_+\|head,tail	phage head-tail adapter protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2131006:2131023	attR	NA	NA	NA	NA
AOH58759.1\|2131264_2131669_+	hypothetical protein	G4KNQ5	Staphylococcus_phage	2.1e-68	99.3
AOH59915.1\|2131665_2132073_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AOH57801.1\|2132073_2132718_+\|tail	phage tail protein	A0A1X9H0J2	Staphylococcus_phage	1.5e-119	100.0
AUN01289.1\|2132759_2132984_+	hypothetical protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
AOH60035.1\|2133033_2133384_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AOH59909.2\|2133628_2138158_+\|tail	phage tail tape measure protein	A0A2I6PDK2	Staphylococcus_phage	0.0e+00	99.7
AOH57469.1\|2138154_2139639_+\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
AOH58067.1\|2139654_2143440_+	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.5
AOH60073.1\|2143429_2143582_+	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
AOH59390.2\|2143628_2143916_+	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
AOH57894.2\|2143973_2144270_+	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
AOH58110.2\|2144419_2144596_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
AUN01290.1\|2144648_2144756_-	hypothetical protein	NA	NA	NA	NA
AOH58254.1\|2144807_2145062_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AOH59204.1\|2145073_2145829_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AOH57861.1\|2146019_2146511_+	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
AUN01291.1\|2147037_2147496_+	amidase	R9QTN8	Staphylococcus_phage	4.9e-85	98.7
AOH58628.1\|2147590_2148040_-	chemotaxis inhibitory protein	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
AOH59494.1\|2148723_2149074_+	inhibitor	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
AOH57546.2\|2149126_2149387_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
AUN01292.1\|2149365_2149674_-	hypothetical protein	M9NTD8	Staphylococcus_phage	2.1e-39	100.0
AUN01293.1\|2149697_2149877_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AOH58731.2\|2150248_2150449_-	hypothetical protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
AOH58850.2\|2150834_2152268_+	protein map	NA	NA	NA	NA
AUN01294.1\|2152278_2152569_+	adherence protein Eap/Map	NA	NA	NA	NA
AOH59447.1\|2152892_2154179_-	aspartate aminotransferase	NA	NA	NA	NA
AUN01295.1\|2154378_2154477_+	hypothetical protein	NA	NA	NA	NA
AOH60116.1\|2154719_2154896_+	hypothetical protein	NA	NA	NA	NA
AOH58122.1\|2155154_2155535_+	GntR family transcriptional regulator	NA	NA	NA	NA
AOH58641.1\|2155531_2156428_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
AOH59823.1\|2156428_2157109_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
AOH59757.1\|2157105_2157978_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
AOH58534.1\|2157977_2158718_+	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
AOH57916.1\|2158783_2159347_-	thioredoxin family protein	NA	NA	NA	NA
AOH57648.1\|2159467_2159992_+	hypothetical protein	NA	NA	NA	NA
AOH59689.1\|2160051_2160609_+	DUF1700 domain-containing protein	NA	NA	NA	NA
AOH57682.1\|2160605_2161448_+	hypothetical protein	NA	NA	NA	NA
AOH57618.1\|2161504_2162545_-	linear amide C-N hydrolase	NA	NA	NA	NA
AOH59337.1\|2162995_2163169_+	hypothetical protein	NA	NA	NA	NA
AOH58627.2\|2163675_2164827_+\|transposase	transposase	P97010	Streptococcus_pyogenes_phage	9.0e-11	31.0
AUN01395.1\|2164865_2166893_+\|transposase	transposase	NA	NA	NA	NA
AOH58636.1\|2166901_2167267_+	taurine dioxygenase	NA	NA	NA	NA
AOH58581.2\|2167295_2167715_-	protein arginine kinase	U3PG23	Staphylococcus_phage	1.1e-30	54.2
AOH59042.2\|2168196_2169876_+\|transposase	IS5/IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.9e-243	77.4

DBSCAN-SWA_5

2252586 : 2306235

Staphylococcus_phage(90.0%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH58668.2\|2252586_2253729_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
AOH57551.1\|2253733_2254204_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
AOH60141.1\|2254361_2254961_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
AOH57691.1\|2254985_2255138_+	hypothetical protein	NA	NA	NA	NA
AUN01305.1\|2255501_2255666_-	nitrogen fixation protein NifR	NA	NA	NA	NA
AOH57954.1\|2255971_2256367_+	hypothetical protein	NA	NA	NA	NA
AOH57583.1\|2256562_2257948_+	class II fumarate hydratase	NA	NA	NA	NA
AUN01306.1\|2258400_2259222_-	RluA family pseudouridine synthase	NA	NA	NA	NA
AOH59888.1\|2259384_2260497_+	histidine kinase	NA	NA	NA	NA
AOH58068.1\|2260518_2261142_+	DNA-binding response regulator	NA	NA	NA	NA
AOH58956.1\|2261497_2261962_+	transcriptional regulator	NA	NA	NA	NA
AOH59848.1\|2262140_2263265_+	DUF445 domain-containing protein	NA	NA	NA	NA
AOH57554.1\|2263333_2263678_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
AUN01307.1\|2263950_2264157_-	hypothetical protein	NA	NA	NA	NA
AUN01308.1\|2264170_2264269_+	hypothetical protein	NA	NA	NA	NA
AOH59778.1\|2264559_2265756_+	exonuclease SbcCD subunit D	NA	NA	NA	NA
AOH58508.2\|2265745_2268682_+	DNA repair protein Rad50	NA	NA	NA	NA
AOH59491.1\|2268678_2269620_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
AOH59816.2\|2269740_2270703_-	foldase	NA	NA	NA	NA
AOH59315.1\|2270907_2271465_-	DUF3267 domain-containing protein	NA	NA	NA	NA
AOH59395.1\|2272197_2272563_-	YtxH domain-containing protein	NA	NA	NA	NA
AOH58347.1\|2272704_2273127_-	HIT family protein	NA	NA	NA	NA
AOH60063.1\|2273260_2274001_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-24	29.8
AOH59027.1\|2273993_2275217_+	multidrug ABC transporter ATP-binding protein	NA	NA	NA	NA
AOH58162.1\|2275340_2275844_-	signal transduction protein TRAP	NA	NA	NA	NA
AUN01309.1\|2276006_2276117_+	hypothetical protein	NA	NA	NA	NA
AOH58535.1\|2276106_2277144_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
AOH57898.1\|2277201_2278125_+	ferrochelatase	NA	NA	NA	NA
AOH59923.2\|2278148_2279549_+	protoporphyrinogen oxidase	NA	NA	NA	NA
AOH59254.1\|2279869_2280424_+	serine hydrolase family protein	NA	NA	NA	NA
AOH57498.1\|2281792_2282557_+	exotoxin	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1
AOH58444.1\|2282837_2283557_+	superantigen-like protein SSL12	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AOH57704.1\|2283591_2284320_+	exotoxin	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AUN01310.1\|2284473_2285244_+	exotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	1.4e-44	43.2
AOH58994.2\|2285282_2286038_+	exotoxin	A0A075M4C7	Staphylococcus_phage	1.0e-39	41.0
AOH57567.2\|2286320_2287097_+	exotoxin	NA	NA	NA	NA
AUN01311.1\|2287314_2287500_-	hypothetical protein	NA	NA	NA	NA
AOH58863.1\|2287648_2288425_-	DUF1828 domain-containing protein	NA	NA	NA	NA
AOH58135.1\|2288445_2288682_-	hypothetical protein	NA	NA	NA	NA
AUN01312.1\|2288759_2289254_-	hypothetical protein	NA	NA	NA	NA
AOH58191.1\|2290087_2290876_-	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	1.3e-138	95.0
AOH59725.1\|2292239_2293175_+	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
AOH59827.1\|2293176_2294160_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
AOH59945.1\|2294530_2295322_-	DUF1828 domain-containing protein	NA	NA	NA	NA
AOH58732.1\|2295326_2295800_-	hypothetical protein	NA	NA	NA	NA
AOH57623.2\|2296055_2296274_+	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	1.4e-26	81.9
AOH60205.1\|2296747_2297326_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	1.9e-49	59.6
AUN01313.1\|2297635_2297854_+	hypothetical protein	NA	NA	NA	NA
AOH57719.1\|2298289_2298997_+\|protease	serine protease	A0A2H4PQN3	Staphylococcus_phage	1.6e-127	97.9
AOH58253.1\|2299121_2299844_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
AOH60017.1\|2299901_2300621_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
AOH59178.1\|2300741_2301461_+\|protease	serine protease	A0A2H4PQP9	Staphylococcus_phage	5.1e-129	99.2
AUN01314.1\|2301409_2301517_-	hypothetical protein	NA	NA	NA	NA
AOH59339.1\|2301618_2302275_+\|protease	serine protease	A0A2H4PQN5	Staphylococcus_phage	1.3e-118	99.1
AOH60125.1\|2302485_2303205_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AUN01315.1\|2303269_2303404_+	hypothetical protein	NA	NA	NA	NA
AOH59102.2\|2303384_2305124_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.8e-287	99.0
AOH60122.1\|2305116_2306235_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	7.6e-39	35.1

DBSCAN-SWA_6

2311468 : 2343435

Staphylococcus_phage(93.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH57937.1\|2311468_2312026_+	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	9.1e-78	96.8
AUN01317.1\|2312223_2312796_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.6e-24	93.1
AOH59777.1\|2312896_2313238_-	DUF3969 domain-containing protein	A0A2H4PQN6	Staphylococcus_phage	3.9e-55	95.6
AOH58740.1\|2313278_2313905_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	1.3e-88	91.3
AOH59921.1\|2313978_2314974_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	9.6e-70	94.4
AOH57681.2\|2315054_2315705_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	5.2e-56	98.6
AOH59066.2\|2316007_2316463_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	4.0e-79	98.6
AOH59583.1\|2316621_2318100_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.5e-284	98.2
AOH59068.2\|2318104_2319106_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.1e-188	98.8
AOH59525.1\|2319102_2319360_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AOH59650.1\|2319425_2319899_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	5.5e-84	99.4
AOH57626.2\|2319903_2320650_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	4.4e-144	100.0
AOH57581.1\|2320902_2322495_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AOH57792.1\|2322866_2324060_+	S-adenosylmethionine synthase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AOH57558.1\|2324184_2325093_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AOH57744.1\|2325304_2326138_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.5e-158	99.6
AOH59652.1\|2328135_2328489_-	camphor resistance protein CrcB	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	94.9
AOH59677.1\|2328485_2328851_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AUN01318.1\|2329106_2329409_-	hypothetical protein	NA	NA	NA	NA
AOH59470.1\|2329668_2330382_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AOH59015.1\|2330821_2331457_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AOH57725.1\|2331752_2332196_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AUN01319.1\|2332182_2332626_-	competence protein ComK	NA	NA	NA	NA
AOH57570.1\|2332738_2333209_-	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AOH59248.1\|2333407_2333632_+	hypothetical protein	NA	NA	NA	NA
AOH58468.1\|2333907_2334762_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AOH57670.1\|2334848_2336141_-	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AUN01320.1\|2336140_2336455_-	ArsR family transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
AOH59199.1\|2336977_2338480_+	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	3.6e-28	97.2
AOH59196.2\|2338972_2340004_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
AOH59950.1\|2340010_2340643_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AOH58862.1\|2340653_2341835_+	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AOH57686.1\|2341847_2342312_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AOH59119.2\|2342433_2343435_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7

DBSCAN-SWA_7

2483611 : 2492651

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH57910.2\|2483611_2484616_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
AOH58999.1\|2484617_2485643_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
AOH59556.1\|2485665_2486805_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.6e-84	44.7
AOH59918.1\|2486823_2487084_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AOH58880.1\|2487358_2489638_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AOH58914.1\|2489840_2492111_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.4e-63	29.3
AOH58897.1\|2492132_2492651_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_8

2560430 : 2568760

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AOH59568.1\|2560430_2562248_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.6e-54	36.0
AOH60216.1\|2562471_2563578_+	RNA polymerase sigma factor SigA	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AOH58451.1\|2563708_2564386_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
AOH59960.1\|2564388_2565489_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
AOH59930.2\|2565602_2566949_+	DEAD/DEAH box family ATP-dependent RNA helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
AOH58041.2\|2566958_2567849_+	endonuclease	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
AUN01347.1\|2567974_2568760_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP016856

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection