CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP020430	Streptococcus sp. FDAARGOS_192 plasmid unnamed2 sequence	0 crisprs	NA	0
CP020431	Streptococcus sp. FDAARGOS_192 chromosome, complete genome	0 crisprs	DinG,WYL,csa3,DEDDh,cas3	7
CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	0 crisprs	NA	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

239701 : 250592

Streptococcus_phage(87.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC22084.1\|239701_240817_+	glycerate kinase	W6LM47	Streptococcus_phage	9.2e-138	86.6
ARC22085.1\|240847_241303_-	DUF1694 domain-containing protein	W6LLD2	Streptococcus_phage	2.3e-66	83.4
ARC22086.1\|241508_242813_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.4e-246	99.5
ARC22087.1\|242962_243148_-	hypothetical protein	W6LMT3	Streptococcus_phage	7.3e-24	90.2
ARC22088.1\|243318_245499_-	LTA synthase family protein	W6LM83	Streptococcus_phage	0.0e+00	94.8
ARC22089.1\|245660_246824_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.2e-212	95.3
ARC22090.1\|246820_247498_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	6.7e-115	94.7
ARC22091.1\|247487_248345_+	shikimate dehydrogenase	NA	NA	NA	NA
ARC22092.1\|248357_249425_+	3-dehydroquinate synthase	NA	NA	NA	NA
ARC22093.1\|249425_250592_+	chorismate synthase	A0A291AU41	Pandoravirus	4.6e-39	34.7

DBSCAN-SWA_2

271278 : 276182

Streptococcus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC22114.1\|271278_271449_+	DNA recombinase	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
ARC22115.1\|271834_273052_+	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
ARC22116.1\|273171_274635_+	ABC-F type ribosomal protection protein Msr(D)	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
ARC22117.1\|274752_275052_-	hypothetical protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
ARC22118.1\|275038_275407_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
ARC22119.1\|275419_275755_-	imsC-like protein	NA	NA	NA	NA
ARC22120.1\|275751_275997_-	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
ARC22121.1\|275993_276182_-	type VI secretion protein ImpB	Q6DMX4	Streptococcus_phage	1.5e-13	90.7

DBSCAN-SWA_3

784682 : 795347

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC22562.1\|784682_786245_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.9e-19	30.3
ARC22563.1\|786532_787117_-	N-acetyltransferase	NA	NA	NA	NA
ARC22564.1\|787401_788421_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	1.3e-26	25.2
ARC22565.1\|788582_788864_-	hypothetical protein	M1PG86	Streptococcus_phage	4.2e-23	58.4
ARC22566.1\|788841_789219_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	2.0e-20	45.8
ARC22567.1\|789215_790631_-	DNA polymerase	M1Q231	Streptococcus_phage	3.0e-194	70.5
ARC22568.1\|790744_791596_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
ARC22569.1\|791608_792238_-	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.8e-32	40.2
ARC22570.1\|792246_792888_-	amino acid ABC transporter permease	NA	NA	NA	NA
ARC22571.1\|793088_793421_-	alkylphosphonate utilization protein	NA	NA	NA	NA
ARC22572.1\|793538_795347_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	2.5e-100	39.4

DBSCAN-SWA_4

1301637 : 1311880

Streptococcus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC22919.1\|1301637_1303590_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	2.6e-143	45.6
ARC22920.1\|1303590_1304151_-	DNA gyrase subunit B	NA	NA	NA	NA
ARC22921.1\|1304236_1304932_-	LrgB family protein	NA	NA	NA	NA
ARC22922.1\|1304924_1305299_-	murein hydrolase regulator LrgA	NA	NA	NA	NA
ARC22923.1\|1305579_1305933_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.8e-39	66.7
ARC22924.1\|1305967_1306462_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.5e-36	46.3
ARC22925.1\|1306516_1307695_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.5e-178	79.6
ARC22926.1\|1307713_1308271_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	4.4e-56	59.6
ARC22927.1\|1308283_1309378_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.1e-171	81.0
ARC22928.1\|1309532_1310426_-	ROK family protein	NA	NA	NA	NA
ARC22929.1\|1310541_1310937_+	lactoylglutathione lyase	NA	NA	NA	NA
ARC22930.1\|1310980_1311880_-	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	32.8

DBSCAN-SWA_5

1634417 : 1682515

Lactobacillus_phage(28.57%)

tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC23212.1\|1634417_1635560_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	9.3e-85	42.8
ARC23213.1\|1635765_1635900_-	50S ribosomal protein L34	NA	NA	NA	NA
ARC23214.1\|1636095_1636659_-	flavodoxin family protein	NA	NA	NA	NA
ARC23215.1\|1636655_1637252_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
ARC23216.1\|1637383_1638427_-	protein jag	NA	NA	NA	NA
ARC23217.1\|1638438_1639245_-	protein translocase component YidC	NA	NA	NA	NA
ARC23218.1\|1639360_1639696_-	ribonuclease P protein component	NA	NA	NA	NA
ARC23778.1\|1639780_1641166_-	argininosuccinate lyase	NA	NA	NA	NA
ARC23219.1\|1641492_1642692_-	argininosuccinate synthase	NA	NA	NA	NA
ARC23220.1\|1643636_1644380_-	DNA-binding response regulator	NA	NA	NA	NA
ARC23221.1\|1644381_1645698_-	GHKL domain-containing protein	NA	NA	NA	NA
ARC23222.1\|1645721_1647002_-	hypothetical protein	NA	NA	NA	NA
ARC23223.1\|1647023_1647914_-	histidine kinase	NA	NA	NA	NA
ARC23224.1\|1647972_1649280_-	GHKL domain-containing protein	NA	NA	NA	NA
ARC23225.1\|1649733_1651188_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
ARC23226.1\|1651423_1653394_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
ARC23228.1\|1654992_1655682_-	50S ribosomal protein L1	NA	NA	NA	NA
ARC23229.1\|1655781_1656207_-	50S ribosomal protein L11	NA	NA	NA	NA
ARC23230.1\|1656378_1656732_+	DUF3397 domain-containing protein	NA	NA	NA	NA
ARC23231.1\|1656826_1657324_-	carbonic anhydrase	NA	NA	NA	NA
ARC23232.1\|1657475_1658171_-	TIGR00266 family protein	NA	NA	NA	NA
ARC23233.1\|1658258_1659620_-	DNA repair protein RadA	NA	NA	NA	NA
ARC23779.1\|1659616_1660084_-	cysteine hydrolase	NA	NA	NA	NA
ARC23234.1\|1660094_1660541_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	Q332E8	Clostridium_botulinum_C_phage	5.5e-33	50.7
ARC23235.1\|1660749_1661352_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.8e-55	54.2
ARC23236.1\|1661370_1662621_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	7.6e-56	52.7
ARC23237.1\|1662737_1663529_+	formate transporter	NA	NA	NA	NA
ARC23238.1\|1663537_1664098_+	hypothetical protein	NA	NA	NA	NA
ARC23239.1\|1664216_1665239_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
ARC23240.1\|1665256_1666171_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	3.7e-76	51.5
ARC23241.1\|1666216_1666891_-	DUF1751 domain-containing protein	NA	NA	NA	NA
ARC23242.1\|1666881_1667409_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
ARC23243.1\|1667477_1668611_-	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
ARC23244.1\|1668688_1669387_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
ARC23245.1\|1669472_1670225_-	HAD family hydrolase	NA	NA	NA	NA
ARC23247.1\|1671733_1672597_-	methyltransferase domain-containing protein	NA	NA	NA	NA
ARC23248.1\|1673017_1673176_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
ARC23249.1\|1673195_1673363_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
ARC23250.1\|1673410_1673662_+	hypothetical protein	NA	NA	NA	NA
ARC23251.1\|1673748_1674267_-	nucleoside deaminase	NA	NA	NA	NA
ARC23252.1\|1675036_1675429_-	single-stranded DNA-binding protein	A1EAD1	Streptococcus_phage	5.7e-26	47.0
ARC23253.1\|1675858_1676536_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC23254.1\|1676801_1677425_-	DUF4479 domain-containing protein	NA	NA	NA	NA
ARC23255.1\|1677456_1677981_-	hypothetical protein	NA	NA	NA	NA
ARC23256.1\|1677984_1678299_-	thioredoxin	NA	NA	NA	NA
ARC23257.1\|1678295_1678580_-	DUF4651 domain-containing protein	NA	NA	NA	NA
ARC23258.1\|1678679_1679747_+	glutamyl aminopeptidase	NA	NA	NA	NA
ARC23259.1\|1679762_1680533_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	6.2e-32	35.4
ARC23260.1\|1680559_1681222_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC23261.1\|1681334_1681781_-\|protease	CAAX protease	NA	NA	NA	NA
ARC23262.1\|1681858_1682515_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

1811096 : 1822520

Staphylococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC23391.1\|1811096_1811795_-	hypothetical protein	Q4Z8Z7	Staphylococcus_phage	2.1e-26	70.7
ARC23392.1\|1811978_1812551_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	1.7e-18	50.8
ARC23393.1\|1812851_1813646_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
ARC23394.1\|1813638_1814481_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	6.3e-14	27.9
ARC23395.1\|1814456_1815287_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.5e-20	32.3
ARC23396.1\|1815299_1815842_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
ARC23397.1\|1815854_1816712_-	DUF4115 domain-containing protein	NA	NA	NA	NA
ARC23398.1\|1816770_1818048_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	8.7e-07	26.6
ARC23399.1\|1818049_1819300_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.3e-92	40.1
ARC23400.1\|1819377_1819755_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	8.8e-24	71.1
ARC23401.1\|1819757_1820858_+	DNA replication and repair protein RecF	NA	NA	NA	NA
ARC23402.1\|1821038_1822520_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.6e-95	40.3

DBSCAN-SWA_7

2161324 : 2166806

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC23698.1\|2161324_2162089_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-15	24.8
ARC23699.1\|2162088_2162799_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.7e-15	26.9
ARC23700.1\|2162933_2163593_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.9e-66	58.7
ARC23701.1\|2163777_2164704_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	9.4e-144	81.8
ARC23702.1\|2164805_2165432_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	1.5e-68	62.3
ARC23703.1\|2165486_2166806_+	DNA/RNA helicase	A0A1X9I5S6	Streptococcus_phage	2.4e-124	52.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP020429

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

80447 : 91379

Staphylococcus_phage(33.33%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC21744.1\|80447_81434_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.2e-56	40.1
ARC21745.1\|81756_81942_-	hypothetical protein	NA	NA	NA	NA
ARC21746.1\|81973_82939_-	hypothetical protein	NA	NA	NA	NA
ARC21747.1\|83535_83835_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
ARC21748.1\|83873_84095_-	hypothetical protein	NA	NA	NA	NA
ARC21749.2\|85079_85277_-\|bacteriocin	ComC/BlpC family peptide pheromone/bacteriocin	NA	NA	NA	NA
ARC21750.1\|85692_86115_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	2.8e-31	48.5
ARC21751.1\|86130_86409_-	hypothetical protein	A0A1P8CWQ3	Bacillus_phage	2.6e-17	57.0
ARC21752.1\|87244_87406_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
ARC21853.1\|87781_88735_+	GHKL domain-containing protein	NA	NA	NA	NA
ARC21753.1\|88746_89496_+	DNA-binding response regulator	NA	NA	NA	NA
ARC21754.1\|90173_91379_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP020431

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP020429

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection