CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP020451	Streptococcus salivarius strain FDAARGOS_259 chromosome, complete genome	2 crisprs	csa3,DEDDh,cas3,WYL,DinG	0	3	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP020451_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020451_1

43739-43813

Orphan

Consensus_repeat	Method
GACCTAAAAAGGTCCACTGGAACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020451_1

>merge|CP020451|1|43739-43813|CRISPRCasFinder
GACCTAAAAAGGTCCACTGGAACTTCCTCGCTTTTTCATTTCTGGGCTCGGACCTAAAAAGGTCCACTGGAACTT

>CP020451|1|1|43739-43813|CRISPRCasFinder
GACCTAAAAAGGTCCACTGGAACTT	CCTCGCTTTTTCATTTCTGGGCTCG
GACCTAAAAAGGTCCACTGGAACTT

Protein	Signature genes	Signature genes Name	Protein_function
CP020451.2\|ARC47957.1\|52602_52974_-\|hypothetical-protein	unknown	unknown	unknown
CP020451.2\|ARC47943.1\|38220_39000_-\|hypothetical-protein	unknown	unknown	unknown
CP020451.2\|ARC47954.1\|49848_50133_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|168880
CP020451.2\|ARC47952.1\|48150_48498_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
CP020451.2\|ARC47949.1\|45466_45976_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
CP020451.2\|ARC47945.1\|41013_42207_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
CP020451.2\|ARC47951.1\|46987_47164_+\|DUF3042-domain-containing-protein	unknown	unknown	gnl\|CDD\|371431
CP020451.2\|ARC47947.1\|43411_43597_-\|DUF3272-domain-containing-protein	unknown	unknown	gnl\|CDD\|314526
CP020451.2\|ARC47955.1\|50206_51742_-\|ClC-family-H(+)/Cl(-)-exchange-transporter	unknown	unknown	gnl\|CDD\|238504
CP020451.2\|ARC47944.1\|38996_40148_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
CP020451.2\|ARC47946.1\|42486_43425_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	unknown	unknown	gnl\|CDD\|237010
CP020451.2\|ARC47940.1\|35148_35385_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131380
CP020451.2\|ARC47938.1\|33619_33808_-\|DNA-directed-RNA-polymerase-subunit-beta	unknown	unknown	gnl\|CDD\|378713
CP020451.2\|ARC47956.1\|51791_52235_-\|flavodoxin	unknown	unknown	gnl\|CDD\|180922
CP020451.2\|ARC47939.1\|33809_35081_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
CP020451.2\|ARC47953.1\|48625_49852_-\|voltage-gated-chloride-channel-protein	unknown	unknown	gnl\|CDD\|239654
CP020451.2\|ARC47950.1\|46000_46912_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
CP020451.2\|ARC47948.1\|43814_45467_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
CP020451.2\|ARC47942.1\|36767_38078_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133045
CP020451.2\|ARC47941.1\|35655_36759_-\|endoglucanase	unknown	unknown	gnl\|CDD\|366548

Protein	Function_ID	Function_description	E-value
CP020451.2\|ARC47954.1\|49848_50133_-\|chorismate-mutase	gnl\|CDD\|168880	PRK07248, PRK07248, chorismate mutase.	7.9578e-40
CP020451.2\|ARC47952.1\|48150_48498_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.42285e-69
CP020451.2\|ARC47949.1\|45466_45976_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	1.17131e-72
CP020451.2\|ARC47945.1\|41013_42207_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
CP020451.2\|ARC47951.1\|46987_47164_+\|DUF3042-domain-containing-protein	gnl\|CDD\|371431	pfam11240, DUF3042, Protein of unknown function (DUF3042). This family of proteins with unknown function appears to be restricted to Firmicutes.	1.01731e-15
CP020451.2\|ARC47947.1\|43411_43597_-\|DUF3272-domain-containing-protein	gnl\|CDD\|314526	pfam11676, DUF3272, Protein of unknown function (DUF3272). This family of proteins with unknown function appears to be restricted to Streptococcus.	3.72715e-09
CP020451.2\|ARC47955.1\|50206_51742_-\|ClC-family-H(+)/Cl(-)-exchange-transporter	gnl\|CDD\|238504	cd01031, EriC, ClC chloride channel EriC. This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked proton utilization. As shown for Escherichia coli EriC, these channels can counterbalance the electric current produced by the outwardly directed virtual proton pump linked to amino acid decarboxylation. The EriC proteins belong to the ClC superfamily of chloride ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge. In Escherichia coli EriC, a glutamate residue that protrudes into the pore is thought to participate in gating by binding to a Cl- ion site within the selectivity filter.	6.95841e-162
CP020451.2\|ARC47944.1\|38996_40148_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	2.70268e-173
CP020451.2\|ARC47946.1\|42486_43425_+\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	8.9655e-133
CP020451.2\|ARC47940.1\|35148_35385_-\|hypothetical-protein	gnl\|CDD\|131380	TIGR02327, conserved_hypothetical_protein, conserved hypothetical integral membrane protein. Members of this protein family are small, typically about 80 residues in length, and are highly hydrophobic. The gene is found so far only in a subset of the Firmicutes in association with genes of the ATP synthase F1 complex or NADH-quinone oxidoreductase. This family includes ywzB from Bacillus subtilis; pfam06612 describes the same family as Protein of unknown function DUF1146.	5.43777e-08
CP020451.2\|ARC47938.1\|33619_33808_-\|DNA-directed-RNA-polymerase-subunit-beta	gnl\|CDD\|378713	pfam11772, EpuA, DNA-directed RNA polymerase subunit beta. This short 60-residue long bacterial family is the beta subunit of the DNA-directed RNA polymerase, likely to be EC:2.7.7.6. It is membrane-bound and is referred to by the name EpuA.	7.49228e-12
CP020451.2\|ARC47956.1\|51791_52235_-\|flavodoxin	gnl\|CDD\|180922	PRK07308, PRK07308, flavodoxin; Validated.	4.73963e-83
CP020451.2\|ARC47939.1\|33809_35081_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
CP020451.2\|ARC47953.1\|48625_49852_-\|voltage-gated-chloride-channel-protein	gnl\|CDD\|239654	cd03682, ClC_sycA_like, ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation competitiveness, and N2 fixation on Phaseolus vulgaris plants, due to its reduced ability for acid resistance. This family is part of the ClC chloride channel superfamiy. These proteins catalyse the selective flow of Cl- ions across cell membranes and Cl-/H+ exchange transport. These proteins share two characteristics that are apparently inherent to the entire ClC chloride channel superfamily: a unique double-barreled architecture and voltage-dependent gating mechanism. The gating is conferred by the permeating anion itself, acting as the gating charge.	2.44706e-170
CP020451.2\|ARC47950.1\|46000_46912_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	1.44567e-134
CP020451.2\|ARC47948.1\|43814_45467_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
CP020451.2\|ARC47942.1\|36767_38078_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	3.02912e-51
CP020451.2\|ARC47941.1\|35655_36759_-\|endoglucanase	gnl\|CDD\|366548	pfam01270, Glyco_hydro_8, Glycosyl hydrolases family 8.	6.02911e-18

>CP020451.2|ARC47947.1|43411_43597_-|DUF3272-domain-containing-protein
MIPQILFITLETIFETVCFNYSLQHGYYFFTAFFGYLLFRRLWTTYVVSRIARAADKSTKK
>CP020451.2|ARC47946.1|42486_43425_+|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MKTYEHVYDILSKSPDFVTGESLAKSLGVSRTAIWKAIQTLQEQGIDITSVRKKGYYLEKGDILLPQDISKQLNIPVYFNPDSNSTQLDAKHGMEKNNPTPALYLASSQKAAKGRFDRHFFAIPQGGIYMSIHLKPNCHFADLPPYTMMAAAAIVKAIQRLTGINTEIKWVNDIYLNNKKMAGILTEAISSIESGRITDVIIGVGLNFSISDFPKELANKATSLFTSEKPSITRNQLISEIWKLFLTIPTSDLVKVYKEKSLVLDKQVTFEQAGKTYTGVAKEIGDKGQLLVLTDDGQEKWLSAGEVSLTSW
>CP020451.2|ARC47945.1|41013_42207_-|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPDAHVAAETAVYTGSVHVFGEVSTTAYVDINRVVRDTIAEIGYNNAEYGFAAESVGVHPSLIEQSPDIAQGVNESLEVRGTGDQDPLDLIGAGDQGLMFGFAIDETPEFMPLPVSLSHKLVKKLADLRKSGEISYLRPDAKSQVTVEYDENDQPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPAEYLDDETKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVANPVSVRVDTFGTATVAESKLEAAVRDLFDLRPAGIIQMLDLKRPIYRQTAAYGHMGRTDIDLPWEKLDKVEALKEAVNH
>CP020451.2|ARC47944.1|38996_40148_-|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MGKLNIMVVFGTRPEAIKMAPLILELKKHQETINTITVVTAQHRQMLDQVLETFEIVPDYDLDIMGKNQSLQEITSKILANFDPVVKKEQPDLVLVHGDTTTTFAAGLVAFYNKVSIGHVEAGLRTYDKYSPYPEEMNRQMTDSLSDLYFAPTQESKANLLSENHKKEAIYVTGNTAIDALKLTVKDNYYHEVLDKIDENKKIILVTMHRRENQGEPMRRVFKTLRHMVDEHSEIEVVYPVHLSPSVQAAAKEILGDHDRIHLIAPLDVFDFHNLASRSYFIMSDSGGVQEEAPSLGKPVLVLRDTTERPEGVKAGTLKLVGTDPDKVKEAMTSLLTEEALYKEMSKAPNPYGDGKASERIVQAIKVYFNLEDSVSEFHEGGN
>CP020451.2|ARC47943.1|38220_39000_-|hypothetical-protein
MSVKRDKKIWYWILCLIFFEALLFLYCNQVNPNLFMFEAFFLILGIAAVCFLTEILITWLIILSFALSIFVLVSGVVYLPLNDTLVLIFSFPLLMGILSKIKYYFYKFISSVQIEEVKASNAYRDLLEDKKPVQALLIHWSHEEQFFELSPREYNHLLTSIYHQILDKLDRFEQVFYVSEGSYLILSKNKSRNLEKIYKTSLEEHLKEMTFTRGSSYQGIQFQSGFLVIDKKNSKKFDNYSELMSNLNRQLETDIIVEY
>CP020451.2|ARC47942.1|36767_38078_-|glycosyltransferase-family-2-protein
MVSQFLMIFTLISIWISLIWGVVILVSAVHFWLKHSDFKVDKEELPYYPKVTIVVPAHNEDVVISQTAKAILNMNYPHDKVELLLFADNCSDNTYQECLAVQALPEYAGRNITIINRKGTGGKAGVLNDALKMADGEYICIYDADAMPETNALYFLVKEVMKDPERRVASFGRNKTRNAKQNFLTRCINQEIVVTQRVHHVGMWHLFKIGRIPGTNFIIQTEFVKSIGGWRNGALTEDTDISFKIMQSGKLIALAYNSEAFQQEPETLKSYYMQRKRWAKGNYEVVISNFKHLFGKGNWRVKLEVANYSCIFFWFNGAIVLSDLIFFANVLAIVLHIFFPTVQIPFAFDASNIYIAQLMLFNWLLMIGLYLLQINVALASQFGQATSKQIWLAILSYFSYAQLFIIVSLDSLWSIIMDKILHREGTTWVKTKRFAE
>CP020451.2|ARC47941.1|35655_36759_-|endoglucanase
MKTKYFKYLWFVVILGLFVFSMFTIRMKTKTDIQDRIYQKWEKHFVVKKGNEAYVKTTNDKDKDVVLSESQSYGMLITVRAAKKGLANQKDFERLYKYYLSHRIEGNQLMSWEQIVQKSAKNVDDHNATDGDLYIAYALIEASKQWPSHKDEYQTQAKALLQDILKYNYNENIGILTVGNWANKDSKYYNLMRTSDTVPKQFQAFYEVTKDKKWLDINNKMLSSLETISSKTKTGLIPDFIWVDESGARVVKPYTISNQFDSTYSYNACRLPYNLTQSNDEKSQKVLNKMLDFFMTQKNVFSNYNLSGKFLDDHQAASFKAPIAFAAEKDQKYLKLVQQNKIVFMQDLPVKNYYDSAIITLVAMEFF
>CP020451.2|ARC47940.1|35148_35385_-|hypothetical-protein
MTILNDMVPLASHLVFIGLTYQMVNTLFDWEKITKNVIVNTGKLRLFLLFISIAIGFLVSSFFIYVLTLCQSLASSIS
>CP020451.2|ARC47939.1|33809_35081_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MDKIIVQGGNTRLSGEVVIEGAKNAVLPLLAATILASEGQTTLTNVPILSDVYTMNNVVRGLDIAVDFDEENNTVVVDASGEILDQAPYEYVSKMRASIVVLGPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAKITQVGGDITATAEKLKGATIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLALLLNEMGADVKGAGTESLVIKGVKALHGTKHAVVQDRIEAGTFMVAAAMTSGDVLIKDAIWEHNRPLISKLLEMGVYVKEEDGGIRVKSDVSQLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMIETVFENRFQHLEEMRRMGLHSEILRDTAMIHGGLPLQGAQVMSTDLRASAALILTGMVAEGTTTVGKLTHLDRGYYQFHEKLAKLGANISRVSEA
>CP020451.2|ARC47938.1|33619_33808_-|DNA-directed-RNA-polymerase-subunit-beta
METGKGYVFRQLLLVLSVCVIGLAFLAIGLMIGYAVLGEGKDPISILKPETWQAIVAKFTGK
>CP020451.2|ARC47948.1|43814_45467_-|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFGEMVGQKVISTTLRQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNHCDICRDITNGSLEDVIEIDAASNNGVDEIREIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKSIKQGAIKEHLASILEKEGLTFDDEALTIIARRAEGGMRDALSILDQALSLSPDNHVSQTVAEEITGSIGLTALDSFVANIRNQDTTQALSNLETLFDNGKSMSRFATDLLEYFRDLLIVKAGGENSHHSPLFEENLSLEQDRLFQLIDLVTSALPEIKTGTHPKIYAEMLTIKLSETHSQMSQEIPGNLQEELDSLRREVEGLRKALKEGKVQGEVAPTRKAKPAYQYKVDREKILTIMRETMENPQKSRQCLDALKATWPEILDSISPQNRALLNGSEPVLANQENAILAFNAAFNAEQVMKRSDLNDMFGNIMSSAAGFSPNIMAVPKAEFEKLRTEFARSLKSKEELEKEDREEYIPQELEFLSDVVEIED
>CP020451.2|ARC47949.1|45466_45976_-|GAF-domain-containing-protein
MVVMTNEEKKSAYEIMLAQAKAVFANEDNALANFSNASALLNTTLPNSVFTGFYLMDNINNELILGPFQGNVSCVRIDLGKGVCGQSAAENRTLIVEDVTKHANYIACDSAARSEIVVPMVKDGKLVGVLDLDSHQVGDYNDVDQDYLEAFVKILLEKTELTFGMFEVN
>CP020451.2|ARC47950.1|46000_46912_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MKTKLIVVAGPTAVGKTALGIKLAQRFNGEIISGDSQQVYRQLNIGTAKATPEEQAAAVHHLIDVRDVDESYSAYDFVTEAEATITDIVSRGKLPIIVGGTGLYLQSLIEGYHLGGQVDQKQVLAYRSELEQLSDQELFDKIDDLGIEIKEINRRRATRALELHRFSENLENTETTYEPFLIGLDDERSLIYDRINTRVDKMVELGLLEEAKWLYDNYPDAQSARGIGYKELFPYFAGNQTLDEALEKLKQNTRRFAKRQLTWFRNRMTVKFYQISSPEYPENVIHDLELFLNEREGEKVGQS
>CP020451.2|ARC47951.1|46987_47164_+|DUF3042-domain-containing-protein
MAKKHSFAKGVATGVIGTAATVAGAVFAVKKTIIEPEEKKLAFIEENRKKAARRRVSR
>CP020451.2|ARC47952.1|48150_48498_-|50S-ribosomal-protein-L19
MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRK
>CP020451.2|ARC47953.1|48625_49852_-|voltage-gated-chloride-channel-protein
MKVKQLSDSQGLSYLHLVMLSLYAILLGVLVGLIDAVFGRVLIGLSEYRDQHIFYLVPALPLAGLLIVYLYQKLAGKAAQGMGLIFKVGHNEEDQVPLRLIPLVTVTTWLTHLFGGSAGREGVAVQLGATVSHAFSRYFKIPNASRIFLTMGMAAGFGGLFQTPIAATFFALEVLILGQLSLPILVPTLIASFVASTTSHLLGLEKFSHFVSDSLTINLGTFVKLALLGLVFGLAGNLFAYLLSVAKKKVASLLPNPYYRVLLGSVVLTCLLLILWKGRYTGLGTNLIALSVGGGTIYPLDWLLKLLLTVFTLSLGFQGGEVTPLFAIGASLGAVLAPVLGFPIPLVAGLGYLSVFGSSTNTLLAPIFIGVEVFGPANAVPYAIVMSFAYLINHKTSIYGQQKMLEMQ
>CP020451.2|ARC47954.1|49848_50133_-|chorismate-mutase
MDLNEIRQQIDTVDNEIVALLEERMKLVTRVSAYKQRTGKAIYDPEREQALLDKVGASVLNPEYKEAIVASFADIMKRSRIYQASKLEKSRYLE
>CP020451.2|ARC47955.1|50206_51742_-|ClC-family-H(+)/Cl(-)-exchange-transporter
MNEIERDFRTQSQHLLWSVWRGLLVGGTAGAVVSLFRWLIAKGAAFSVAIYKDALHNPLLILGIVLVNLLIALFIGYLIKQEKDIKGSGIPHVEGELMGLLHPSWWSVLWRKFLGGVLGISMGLMLGREGPSIQLGAMTAKGLAESLKLSAREKRVLIAAGAAAGLSAAFNAPIAGLLFVVEEVYHHFSRHVWVTALTASLVANAVSLRIFGQVPVLAMTEKLPVFPLKDYWILIVLGIFLGVLGYGYEWVVLRIGKVYQGLGKIFHLPSHFHGLLAVLFIIPIGLYFPYLLGGGNELILALNGLHPALTVAILYLAIRFIWSMLSFGSGFPGGIFLPILTLGALSGSVFAAAFENLGFLQVSQFPIFIILGMAGYFGAVSKAPLTAMILVTEMVGDLHQLMTIGVVTLIAYLVMDFMGGEPVYEAMLHNLIAHEPKQVDNIPTMIDLPVTDSLAGRLVKDLTLPDGVLISTQIFQDQSEVVHGDTRLKAGATLYLVVNESNISQVRKLFL
>CP020451.2|ARC47956.1|51791_52235_-|flavodoxin
MALAKIVYASMTGNTEEIADIVAKKLEELGHTVDVDECTTVDAADFEDADVCIVATYTYGDGELPDEIVDFYEDLADLDLSGKIFGVVGSGDTFYDYFCHSVDEFENQFTFTGATKGADSVKVDLSAEDEDIENLEVFAEKISEALA
>CP020451.2|ARC47957.1|52602_52974_-|hypothetical-protein
MRYLKRLARRYPMQTFLFLFNAGVFTWLQTTGTMIANRLGLSGDGIWIYIPTWVKTLTSHSIESIQTLYSASGWSWLITSMLLTWLLTFLRGLMRAVIIILLVGVGLWLVYRHFELLQNLKLS

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Crispr_ID: CP020451_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP020451_3

771234-771334

Orphan

Consensus_repeat	Method
AAAAATTGGTATAGTCTGATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP020451_3

>merge|CP020451|3|771234-771334|CRISPRCasFinder
AAAAATTGGTATAGTCTGATTTTTATTTACAAAACCAACAATGATAGTTTACAACAAGTAATAATAGTTGTCAAATAGAAAAATTGGTATAGTCTGATTAT

>CP020451|3|2|771234-771334|CRISPRCasFinder
AAAAATTGGTATAGTCTGATTTT	TATTTACAAAACCAACAATGATAGTTTACAACAAGTAATAATAGTTGTCAAATAG
AAAAATTGGTATAGTCTGATTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP020451.2\|ARC48598.1\|769371_771186_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
CP020451.2\|ARC48606.1\|780150_780594_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|197670
CP020451.2\|ARC48608.1\|781728_782595_-\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
CP020451.2\|ARC48601.1\|774280_775096_-\|hydrolase	unknown	unknown	gnl\|CDD\|197313
CP020451.2\|ARC48603.1\|777534_778473_-\|malate-transporter	unknown	unknown	gnl\|CDD\|273356
CP020451.2\|ARC48604.1\|778636_779449_-\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|334323
CP020451.2\|ARC48597.1\|767415_769185_-\|PTS-mannitol-transporter-subunit-IICBA	unknown	unknown	gnl\|CDD\|225123
CP020451.2\|ARC48591.1\|759739_760456_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
CP020451.2\|ARC48593.1\|762342_763215_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|273772
CP020451.2\|ARC48607.1\|780758_781736_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
CP020451.2\|ARC48596.1\|765415_767380_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|226234
CP020451.2\|ARC48602.1\|775193_777380_-\|PTS-glucose/maltose-transporter-subunit-IIBCA	unknown	unknown	gnl\|CDD\|131058
CP020451.2\|ARC48595.1\|764988_765426_-\|PTS-mannitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
CP020451.2\|ARC48594.1\|763833_764979_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP020451.2\|ARC48600.1\|772827_774177_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP020451.2\|ARC48589.1\|758406_759156_-\|isoprenyl-transferase	unknown	unknown	gnl\|CDD\|184840
CP020451.2\|ARC48590.1\|759284_759614_-\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|235822
CP020451.2\|ARC48609.1\|782674_783034_-\|hypothetical-protein	unknown	unknown	unknown
CP020451.2\|ARC48605.1\|779441_780149_-\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
CP020451.2\|ARC48592.1\|760611_762189_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
CP020451.2\|ARC48598.1\|769371_771186_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP020451.2\|ARC48606.1\|780150_780594_-\|HTH-domain-containing-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.31668e-15
CP020451.2\|ARC48608.1\|781728_782595_-\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	5.54747e-149
CP020451.2\|ARC48601.1\|774280_775096_-\|hydrolase	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	5.47787e-99
CP020451.2\|ARC48603.1\|777534_778473_-\|malate-transporter	gnl\|CDD\|273356	TIGR00946, Uncharacterized_transporter_MTH_1382, he Auxin Efflux Carrier (AEC) Family. [Transport and binding proteins, Other].	7.14663e-35
CP020451.2\|ARC48604.1\|778636_779449_-\|metal-ABC-transporter-permease	gnl\|CDD\|334323	pfam00950, ABC-3, ABC 3 transport family.	2.90165e-62
CP020451.2\|ARC48597.1\|767415_769185_-\|PTS-mannitol-transporter-subunit-IICBA	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP020451.2\|ARC48591.1\|759739_760456_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	2.99288e-137
CP020451.2\|ARC48593.1\|762342_763215_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|273772	TIGR01716, HTH-type_transcriptional_regulator_rgg, transcriptional activator, Rgg/GadR/MutR family, C-terminal domain. This model describes the whole, except for a 60 residue N-terminal helix-turn-helix DNA-binding domain (pfam01381) of the family of proteins related to the transcriptional regulator Rgg, also called RopB. Rgg is required for secretion of several proteins, including a cysteine proteinase associated with virulence. GadR is a positive regulator of a glutamate-dependent acid resistance mechanism. MutR is a transcriptional activator for mutacin biosynthesis genes in Streptococcus mutans. This family appears restricted to the low-GC Gram-positive bacteria, including at least eight members in Lactococcus lactis. [Regulatory functions, DNA interactions].	3.09233e-23
CP020451.2\|ARC48607.1\|780758_781736_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	9.80373e-118
CP020451.2\|ARC48596.1\|765415_767380_-\|phosphotransferase	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.07433e-23
CP020451.2\|ARC48602.1\|775193_777380_-\|PTS-glucose/maltose-transporter-subunit-IIBCA	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
CP020451.2\|ARC48595.1\|764988_765426_-\|PTS-mannitol-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	1.38628e-59
CP020451.2\|ARC48594.1\|763833_764979_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP020451.2\|ARC48600.1\|772827_774177_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP020451.2\|ARC48589.1\|758406_759156_-\|isoprenyl-transferase	gnl\|CDD\|184840	PRK14830, PRK14830, undecaprenyl pyrophosphate synthase; Provisional.	3.20398e-177
CP020451.2\|ARC48590.1\|759284_759614_-\|preprotein-translocase-subunit-YajC	gnl\|CDD\|235822	PRK06531, yajC, preprotein translocase subunit YajC; Validated.	3.84081e-19
CP020451.2\|ARC48605.1\|779441_780149_-\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	1.49987e-106
CP020451.2\|ARC48592.1\|760611_762189_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.05161e-68

>CP020451.2|ARC48598.1|769371_771186_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNTNATEILIQGLEKLEYRGYDSAGIFVIDEGKKGHLVKSVGRIADLQAKIDSEVVGSTGIGHTRWATHGQATEANAHPHTSANGRLILVHNGVIENYLQIKDEYLSGDTFKGETDTEIAVHLIGHFVDEGNSVLDAFKKALHIIQGSYAFALVDSENPDTIYVAKNKSPLLIGIGNGYNMVCSDAMAMIRETSEFMEIHDKELVVLTKDSVTVSDYDGNLKERNTYTAELDLSDIGRGTYPYYMLKEIDEQPTVMRKLISTYSDENGKLKVDPAIVKTVQESDRIYILAAGTSYNAGFAAKNMIERLTDTPVELGVASEWGYNMPLLSKKPMFILLTQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTKAYTAQIAALAFLSKAVGEANGKKEAIEFDLVHELSIVAQSIEATLSEKEAISEKVEKLLAATRNAFYIGRGNDYYVAMEASLKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIALISSSSVVASHTRGNIQEVVARGANALTIVEEELAKEGDDIIVNQVHPFLAPISMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>CP020451.2|ARC48597.1|767415_769185_-|PTS-mannitol-transporter-subunit-IICBA
MENSSSFKVRLQKLGTSLSNMVMPNIPALIAWGVLTALVIPDGYIPNEQLATMVSPMLKYVIPLMIGFTGGYNVYSHRGGIVGAIAAFGAIAGSDVTMIIGAMVMGPLAAWLMKKFDQNVQPKIRPGFEMLVNNFSAGFIAFGLMILSFYGIGPVVANLTGLVGQGVDVLVKLSLLPLANIIIEPAKILFLNNALNHGIFTPIGTQQVTEAGKSILFLLEANPGPGLGILLAYALFGRGSAKSSSWGAMIIHFLGGIHEIYFPYVMMKPAMFLAVIAGGVSGTFTFQLLGAGLTAPASPGSIIAIMGMSPKGWGPHLVVLAGVLVATLVSFIVGALVLRFDNSEEASLEEAKAASTAAKAQSKGKVIDKTSESEEISTDSVKRIIFACDAGMGSSAMGASLLRNKIKKAGLDNIPVTNQAISTLDDTDYTLIVTQEELADRAKQRTPRAIHVAVDNFLTSPKYDDIVSQLLNKEQNNVKLKSEDNNSESPNVDLDNIDEVVFAYGVNQGSATMGCETLKTIFRVNNINIPVVTVSNANLSDHSSPNILIVTTIPNQTEVQAIAPNSQLLVVDSLVTTPEYDKIVARMNK
>CP020451.2|ARC48596.1|765415_767380_-|phosphotransferase
MIFTNREEKLVDAFLELGSLSLKEMSDILQVSSRTVYRTLSDLMLTLKTENIHVVKKGKQYYLEGDLTPLKNANDSTTIISNRLLGITYDLLNSSKPLINEELQRKYQVSNVTIIQSISQIEERLKDFKLDIVRNRGYLIEGTIWEKRKVLAILLTNAISTQDFNNDQYNLFECLNKDILNHCKISFDKEKSNLGDLDPKIRQYLIILLALADNTLPTNLVGSVSRKALGISQSIFTNLSKLVSSKLYGLQEVLFFASILDETDLMRQETPLFQERFDGDFYYSVSQLIDMVSRLTKIEFFRDKQLFHFLFQHLKLSLAVPILFPEFSRNHVAYLATQNNTYLHNVVSLVVKDIFPNYIQNDYEYSLLTLHFASSLRRSPDIYPISMLLVTDERPLVRSVLVSKIKSAAPFVGDIRVISTSQLKDHDTEDYDYCLSTKHISQYQMDIISIFPSTKEIIELQERLQDVQLNRTIRQRKRDVEIKKYDIQTYLSASTHLLRNFKLISYSNPKEFTEMVNTLVNYLDNVSEKSYLAAKLVSRFDESPMAIPKTNLLLLHTQSHAIVESQFLVVQLDKPVLSKSMNHELEEVHRVLVMLTKINESDEVRDLMTAISQSIIENNLYTEIYKTGNREILYQLLNTIFNERIKKLEEKNEI
>CP020451.2|ARC48595.1|764988_765426_-|PTS-mannitol-transporter-subunit-IIA
MKFEKNLIKLNQSFDSKEEAIRYCGRQLFEAGHVNESYIDAMIQRDRELSVYMGNFIAIPHGTDSAKNEVKSSGITIVQVPSGVNFGDDENPKVATVLFGIAGLGNEHLEIIQKISIFCADVDNVVKIADAQSVEQIIQLLSSVE
>CP020451.2|ARC48594.1|763833_764979_-|mannitol-1-phosphate-5-dehydrogenase
MKRAVHFGAGNIGRGFIGELLFENDFEITFVDVNEEIINALNDRGSYEIEIAEEGQRKIKVSNVLGINNAKDPELVIDAISKADLVTTAIGPNILPYIAELVAKGIMERQASGNKEPLDILACENMIGGSQFLYEEVKKYLTPEGIEFTKELIGFPNAAVDRIVPAQHHEDPLFVIVEPFNEWVVETSRMKNPDLRLEGVHYEKNLEPFIERKLFSVNSGHATSAYTGAHFGAKTILEALQNPTVKTKVESVLTEIRNLLIAKWGFDEEALADYHRVILSRFENPFIVDDVKRVARTPIRKLGYDERFIRPIRELRERDLSYSNLLQTVAYVFSYRDEDDPQSVELQRMLENQELTDVVKEVTGVTDKVLVEEIVSAVEKN
>CP020451.2|ARC48593.1|762342_763215_-|helix-turn-helix-domain-containing-protein
MIGPVEMGALLKKIRLSKNLTLKELASDYLSVSFLSKFERGESDISLSRFFLLLDKLDVSIEEFYGILSQDNPTHTEKLLESASKAYYQNDSLSLQKYAGEERHKFELTQDKSFLYNSIMLESFLASVSNKEVDAKKVRELTDYLFSIEQWGKRELIILGNSMSFISTQTLNVLTKEIVYRTRLFGNSDSNQRIRISLLINAASEFLRRDELDLAKYYLDLVNDSGIPEVLLYERHELIFVMGSYLIKSGEVAEGRNLIEGCLETLRTLGAEKLLLAKESEYQELLNSTI
>CP020451.2|ARC48592.1|760611_762189_-|ABC-transporter-ATP-binding-protein
MRTYILKYKYDNLVHILLLALNAAIFVSASVTLALMTNQLVSKRIQSFLALLGLEVGLYIIYLVLNYIIAVHQTKLIQKMTLSIRQSYLSKIIHHSFSEFRKSDIGEHLSVLNNDIQLIESNGFTSIYTLCSTVFTTLFSIIALLSYDVRIVLLAIFLTLCLTYLPKPFTNKMQKSMEIFSKANEELVSGISDQLYGYADVYYASRKQIFLRQVRSIVEKYIVQKIIFTKRKTSTETLMALFSVIAQMLILLLTGLLIIFGNITVGTIASVGQISGNIFNSLSTINQLQVTIKSVDPILKKFHDFPEGPKTCIATIQDVRFENVSYHFGDKAIFEGFTQTFKKGGKYAITGCSGSGKSTLLNIFLGNLKDYEGKILFGKLESKEIDENSIVSECAYVGSQTHIYNDTLRNNLTLWNEAITDTQIKKVLERVNLLSFLNRIDEQVSDGSFSEGQKQRIGLIRAFLKGCSVVIFDEATANLDHNNATRIEHLLLSDPNITYITVTHHLIKENEPYFDKIIRLGEGTE
>CP020451.2|ARC48591.1|759739_760456_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKQGEPDPESNSALKFVLDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRTAFGKNGGNMGASGSVSYMFDKKGVIVFAGEDADAIFEQLLEADVEVEDVEAEDGTITVYTEPTDLHKALEALRANGQEEFQVTELEMIPQTEVTLEGEDLEVFEGLIDALEADDDVQKVYHNVADM
>CP020451.2|ARC48590.1|759284_759614_-|preprotein-translocase-subunit-YajC
MNMMLVLAIYVVAIVAYVAFSRRRQAKAQEDRFAGLAKGAEVETIGGLIAIVDEIDKENNRIVLDAEGVFLTFDLSRSIMKVITPAPTTETTKKTIIEEDSAIESSDEK
>CP020451.2|ARC48589.1|758406_759156_-|isoprenyl-transferase
MFKFRKKSHQEVLDNIPNHIGIIMDGNGRWAKKRLQPRVMGHKAGMDALQKVTIEASQLGVKVLTVYAFSTENWSRPQDEVKFIMNLPVEFFNKYVPELDKNNVRILTIGDNSRLPKETLDALEKAVEQTKHNSGLVLNFALNYGGRAEIVSAVQAIAKEVEAGKLSPEAIDDDLIAKHLMTDKLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTDVFWPDFDQQGLRQAISDYNKRHRRFGGV
>CP020451.2|ARC48600.1|772827_774177_-|glucose-6-phosphate-isomerase
MSHITFDYSKVLGKFVAPHEVDYFQPQVTAADEMIRKGTGAGADFLGWRDLPENYDREEFDRILKAAEKIKKDSDILVVIGIGGSYLGAKAAIDFLNNHFANLQTKEERKAPQILYAGNSISSSYLADLVDFVADKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWDTFVVPDNVGGRFSVLTAVGLLPIAASGADIKALMEGANAARKDYSSSKISENEAYQYAVLRNILYRKGYPVEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQYIQEGTRNVFETVIRVDKPRKNIIIPELEEDLDGLGYLQSKDVDFVNKKATDGVLLAHTDGGVPNMFVTIPEQDAFTLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKKNMFALLGKPGFEELGAELNARL
>CP020451.2|ARC48601.1|774280_775096_-|hydrolase
MKFLTLNTHSWMEEDAEGKFQTLKEQILKAQYDIICFQEVNQEIETSVVDTDAYYHALPSATPIHQDHFVRLLVEKLAEEGLQYHWTWAYNHIGYDHLNEGVAVLSRQPLTASEILVSDVDDPTDYHTRRVAVAETTVDGREVAVASVHLSWWDKGFQEEWARIEERFKAIGKPLILAGDFNNPAGREGHQAILASSLNLQDSFEVAKETTGSYTVGPGIDGWKGNEEPLRIDYVFASQDWTVERLSVIFDGNNQPLVSDHYGLEAELTFK
>CP020451.2|ARC48602.1|775193_777380_-|PTS-glucose/maltose-transporter-subunit-IIBCA
MNKLKEKFGFEFWQKFGKALMVVIAVMPAAGLMISLGKTVAMINPNVAPLVITGGFLEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINRLTGSIFGVTSDILADKAATVHTVFGQSIKVSDYFISVLEAPALNMGVFVGIISGFIGATAFNKYYNFRKLPEALSFFNGKRFVPFVVILRSAIAAIVLAIVWPVIQSGINGFGMWIANSKETAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGTYEVLTGAAKGTEVLGQDPLWLAWVTDLANLKGAHPEQYKHVLESVTPARFKVGQMIGSFGILMGIVVAIYRNVDDDKKHQYKGMLTATALATFLTGVTEPIEYMFMFVATPLYIVYALVQGCAFAMADIVNLRVHSFGSIEFLTRTPLAINAGLAMDIVNFIWVTVLFGVIMFFIANFMIKKFDYATPGRNGNYEQADDASSESAGSASAGTSSASSQVINIINLLGGRANIVDVDACMTRLRVTVKDAEKVGTEEQWKAEGAMGLVMKGQGVQAIYGPKADVLKSDIQDVLDSGEVIPETLPSQMTAVQKAEANFKGVTDEVHSVADGQVINIEDVKDPVFSQKMMGDGFAVEPENGKIVSPVAGKVTSIFPTKHALGLVTDNGLEVLVHIGLDTVSLEGKPFDVKVTEGQTVAAGDLLVEANLDAIREAGRETSTVVVFTNADAIKSVKVEHTGKLAANAPVAKVEL
>CP020451.2|ARC48603.1|777534_778473_-|malate-transporter
MEIFLTSISGILVILGMILVGFVMGEKGWFDDKSRGLIAKLVTQIALPCYMLYTITQRFTATDLLKMLPELRFPALSMVILLGIATAVASIFAVKKERRGLFISMFFNSNTIFVGLPINQALFGDASIPYVLIYYMCNTTFFWTLGTYLIQRDGEGEAEFDLKTSLKKIFSPPLMGFMLGLIIVILHIKLPTFLASDLKYLGSLTTPLSMIFIGLSVSNAGVKQLVLKKDQVLILLGRFVVAPFLMAAIVYWAPLPTLMKQVFIIQSAMPVMTNAPVVAKLYGADSDYAAVMVTETTLATMVVIPILMVLMA
>CP020451.2|ARC48604.1|778636_779449_-|metal-ABC-transporter-permease
MISELLAYDFMQRAILAVIAISIFSPILGLFLILRRQSLMSDTLSHVSLAGVAVGIFLGLSTTWMTLVVVVIAALVLEYLRVSYKHYMEISTAILMSMGLAVALILSNKAGSSSMSLDSYLFGSIITISPEQVRALFVIAAIILVLTLLFIRPMYLLTFDEDTAHVDGLPVRLMSLLFNIVTGIAIALMIPAAGSLLVSTIMILPAAIGMKIGQTFKSVIFWAIGIGLVGMLSGIFISYYWETPASATITLIFIAFFGLVSIFEPLLKAE
>CP020451.2|ARC48605.1|779441_780149_-|metal-ABC-transporter-ATP-binding-protein
MRYITVEGLSFQYDAEPVLDNIHYHLDSGEFVTLTGENGAAKSTLIKATLGILKPKKGTVTISETNKDGKKLRMAYLPQQIASFNAGFPSTVYEFVKSGRYPRQGWFRRLTKHDLEHVQRALESVGMWENRHKQIGRLSGGQKQRAVIARIFASDPDIFVLDEPTTGMDAGTANTFYELMHHSAHKHGKSVLMITHDPEEVKEYTDRNIHLVRNQKLPWRCFNVHEKDGEEHKHD
>CP020451.2|ARC48606.1|780150_780594_-|HTH-domain-containing-protein
MLELEEQVNQLINQIVLKSENQHELLIGQCRSQVKLTNTQEHILMLLAEGRKTNSELAKTLNVSQAAVTKAVKTLVKEGMLEAKKDKDDGRVTYFVLTQEAHPIAQEHEEHHQETLGVYRSVLDQFDNQERQVIGRFLTTLAEKIEE
>CP020451.2|ARC48607.1|780758_781736_-|tRNA-dihydrouridine-synthase-DusB
MTKLNSSFMIGNVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLVVMEMISEKGLLYNNETTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIVDINMGCPVNKVVKNEAGAKWLKDPDKIYHIVKEVTSVLDIPLTVKMRTGWSNSDLAVENALAAESAGVSALAMHGRTREQMYTGHCDHETLAHVAKAITKIPFIGNGDVRSVQDAKLMIEELGVDAVMVGRAAMNNPYIFTQINHFFETGEELPELPFDKKLDIAEDHLKRLVDLKGEMIAVREFRGLAPHYLRGTAGAAKVRGEVSRAESVAQVEEIFATLR
>CP020451.2|ARC48608.1|781728_782595_-|Hsp33-family-molecular-chaperone-HslO
MDKLIKTISESGSFRAYVLDSTETVRTAQEKHNTLSSSTVALGRTLIANQILAANQKGESKITVKVIGNSSFGHIISVADTKGHVKGYIQNPGVDIKKTATGEVLVGPFMGQGQFVSIIDYGTGNPYTSSTPLISGEIGEDFAYYLTESEQTPSAVGLNVLLDEEDKVKVAGGFMLQVLPGASEEEIARYEKRIQEMPAISTLLESDDHIEALLNAIYGDEPFKRLSEEELSFECDCSRERFENALLTLGKDELQAMKDEDHGAEIVCQFCQNKYEFSEADLEELIND
>CP020451.2|ARC48609.1|782674_783034_-|hypothetical-protein
MGVYNSDWLLNQIRGTANVVSKAFKFETLDIDLGQVEDERGRTIDGNDYIDDLLIHEQYDQATTFIHSQLKRLTTNDYNLLVSVYMEYLENLPPVIRQKHHFDDRKIASLREKLSEFSW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP020451_1	1.1\|43764\|25\|CP020451\|CRISPRCasFinder	43764-43788	25	MK448851	Streptococcus phage Javan14, complete genome	27770-27794	5	0.8
CP020451_4	4.1\|2249698\|34\|CP020451\|CRISPRCasFinder	2249698-2249731	34	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	19387-19420	10	0.706
CP020451_2	2.2\|212282\|34\|CP020451\|PILER-CR	212282-212315	34	MN693484	Marine virus AFVG_25M226, complete genome	950-983	11	0.676

1. spacer 1.1|43764|25|CP020451|CRISPRCasFinder matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 5, identity: 0.8

cctcgctttttcatttctgggctcg	CRISPR spacer
ataagctttttcatttctgggctag	Protospacer
 .  ******************* *

2. spacer 4.1|2249698|34|CP020451|CRISPRCasFinder matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 10, identity: 0.706

aaccggtttttctggaacttcaaccacttttggt	CRISPR spacer
tttaagcttttctggaacttcatcctcttttaat	Protospacer
  . .*.*************** ** *****..*

3. spacer 2.2|212282|34|CP020451|PILER-CR matches to MN693484 (Marine virus AFVG_25M226, complete genome) position: , mismatch: 11, identity: 0.676

ttcactctttggtgtttctgatgctgaagtctcg	CRISPR spacer
tggcggtattgggctttctgatgctgaagtctat	Protospacer
*     . ****  ******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

238775 : 282744

Streptococcus_phage(40.0%)

protease,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC49814.1\|238775_240062_-\|protease	collagenase-like protease	Q6DW11	Phage_TP	1.6e-40	32.2
ARC48108.1\|240157_241087_-	U32 family peptidase	NA	NA	NA	NA
ARC48109.1\|241325_241622_+	DUF3270 domain-containing protein	NA	NA	NA	NA
ARC48110.1\|241677_242118_-	hypothetical protein	NA	NA	NA	NA
ARC48111.1\|242130_242529_-	DUF948 domain-containing protein	NA	NA	NA	NA
ARC48112.1\|242653_243445_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
ARC48113.1\|243444_244374_-	HPr kinase/phosphorylase	NA	NA	NA	NA
ARC48114.1\|244500_244764_-	PspC domain-containing protein	NA	NA	NA	NA
ARC48115.1\|244829_245270_-	SprT family protein	NA	NA	NA	NA
ARC48116.1\|245256_247389_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
ARC48117.1\|247806_248709_+	permease	NA	NA	NA	NA
ARC48118.1\|248708_249524_+	TIGR03943 family protein	NA	NA	NA	NA
ARC48119.1\|249576_251238_-	STAS domain-containing protein	NA	NA	NA	NA
ARC48120.1\|251477_252092_-	DUF2140 domain-containing protein	NA	NA	NA	NA
ARC48121.1\|252187_252829_-	lipase	NA	NA	NA	NA
ARC48122.1\|252855_253467_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC48123.1\|253570_253933_-	hypothetical protein	NA	NA	NA	NA
ARC48124.1\|253937_254315_-	hypothetical protein	NA	NA	NA	NA
ARC48125.1\|254327_254690_-	hypothetical protein	NA	NA	NA	NA
ARC48126.1\|254686_255079_-	DUF1722 domain-containing protein	NA	NA	NA	NA
ARC48127.1\|255254_255674_+	hypothetical protein	NA	NA	NA	NA
ARC48128.1\|255773_255971_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AVH84095.1\|256022_256334_-	hypothetical protein	NA	NA	NA	NA
ARC48129.1\|257029_257233_-	CsbD family protein	NA	NA	NA	NA
ARC48130.1\|257489_257729_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
ARC48131.1\|258432_259458_+	TIGR00341 family protein	NA	NA	NA	NA
ARC48132.1\|259561_260443_+	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
ARC48133.2\|260735_261419_-	alpha/beta hydrolase	NA	NA	NA	NA
ARC48134.1\|261405_262422_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
ARC48135.1\|262442_263198_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-12	28.6
ARC48136.1\|263202_264246_-	iron ABC transporter permease	NA	NA	NA	NA
ARC48137.1\|264367_265120_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC48138.1\|265168_266008_-	DUF4300 domain-containing protein	NA	NA	NA	NA
ARC48139.1\|266322_266865_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AVH84096.1\|267036_268803_+	MFS transporter	NA	NA	NA	NA
ARC48140.1\|268962_270210_-	DUF4767 domain-containing protein	NA	NA	NA	NA
ARC48141.1\|270328_270601_-	hypothetical protein	NA	NA	NA	NA
ARC48142.1\|270728_271364_-	copper homeostasis protein CutC	NA	NA	NA	NA
ARC48143.1\|271404_272229_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC48144.1\|272278_272851_-	HD domain-containing protein	A0A1D6Y7U0	Golden_Marseillevirus	1.1e-09	30.1
ARC48145.1\|272950_273520_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	2.7e-16	47.8
ARC48146.1\|273645_274488_+	DegV domain-containing protein	A0A1X9I5J4	Streptococcus_phage	1.3e-107	69.9
ARC48147.1\|274708_275881_+	MFS transporter	NA	NA	NA	NA
ARC48148.1\|276024_276762_-	DUF4336 domain-containing protein	NA	NA	NA	NA
ARC48149.1\|276794_277571_-	alpha/beta hydrolase	NA	NA	NA	NA
ARC48150.1\|277702_278581_-	phosphotransferase family protein	NA	NA	NA	NA
ARC48151.1\|278687_279296_-	peptidase S51	NA	NA	NA	NA
ARC48152.1\|279472_280516_-	EamA family transporter	NA	NA	NA	NA
ARC48153.1\|280821_281142_-	competence protein TfoX	NA	NA	NA	NA
ARC48154.1\|281411_281903_-	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
AVH84097.1\|281991_282744_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_2

290022 : 297959

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVH84098.1\|290022_290211_+	type VI secretion protein ImpB	Q6DMX4	Streptococcus_phage	1.5e-13	90.7
ARC48163.1\|290207_290453_+	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
ARC48164.1\|290449_290785_+	imsC-like protein	NA	NA	NA	NA
ARC48165.1\|290797_291166_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
ARC48166.1\|291152_291452_+	hypothetical protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
ARC48167.1\|291569_293033_-	Msr family ABC-F type ribosomal protection protein	A0A1B0RXA0	Streptococcus_phage	2.8e-251	96.9
AVH84099.1\|293152_294370_-	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
ARC48168.1\|294755_294926_-	DNA recombinase	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
ARC48169.1\|295871_297959_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.2e-114	36.2

DBSCAN-SWA_3

310572 : 321476

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC48184.1\|310572_311739_-	chorismate synthase	A0A291AU41	Pandoravirus	9.3e-40	34.9
ARC48185.1\|311739_312807_-	3-dehydroquinate synthase	NA	NA	NA	NA
ARC48186.1\|312819_313677_-	shikimate dehydrogenase	NA	NA	NA	NA
ARC48187.1\|313666_314344_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.4e-114	92.4
ARC48188.1\|314340_315504_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	8.5e-211	94.6
ARC48189.1\|315665_317852_+	LTA synthase family protein	W6LM83	Streptococcus_phage	0.0e+00	95.0
ARC48190.1\|318026_318212_+	hypothetical protein	W6LMT3	Streptococcus_phage	1.9e-24	93.4
ARC48191.1\|318364_319669_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.4e-246	99.5
ARC48192.1\|319874_320330_+	DUF1694 domain-containing protein	W6LLD2	Streptococcus_phage	2.3e-66	83.4
ARC48193.1\|320360_321476_-	glycerate kinase	W6LM47	Streptococcus_phage	9.2e-138	86.6

DBSCAN-SWA_4

608997 : 614444

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC48448.1\|608997_610317_-	DNA/RNA helicase	A0A1X9I5S6	Streptococcus_phage	2.0e-123	52.8
ARC48449.1\|610371_610998_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.5e-70	62.3
ARC48450.1\|611099_612026_+	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	9.4e-144	81.8
ARC48451.1\|612175_612835_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.5e-66	59.2
ARC48452.1\|612969_613680_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.3e-15	26.9
ARC48453.1\|613679_614444_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.9e-15	24.8

DBSCAN-SWA_5

1070701 : 1108468

Streptococcus_phage(56.67%)

capsid,tRNA,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC48870.1\|1070701_1071958_-\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	3.3e-75	41.6
ARC48871.1\|1072059_1074483_+	penicillin-binding protein	NA	NA	NA	NA
ARC48872.1\|1074842_1078424_+	DNA-directed RNA polymerase subunit beta	A0A2P0VMZ3	Tetraselmis_virus	1.7e-39	25.7
ARC48873.1\|1078524_1082163_+	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	5.8e-64	25.6
ARC48874.1\|1082325_1082688_+	DUF1033 domain-containing protein	NA	NA	NA	NA
ARC48875.1\|1082769_1083711_+	competence protein CglA	NA	NA	NA	NA
ARC49823.1\|1083604_1084693_+	competence protein CglB	NA	NA	NA	NA
ARC49824.1\|1084769_1086206_-	recombinase family protein	A0A2H4J6X5	uncultured_Caudovirales_phage	1.0e-261	95.6
ARC49825.1\|1086356_1086941_-	hypothetical protein	A0A2H4J009	uncultured_Caudovirales_phage	6.4e-74	95.9
ARC48876.1\|1086955_1087333_-	ImmA/IrrE family metallo-endopeptidase	F8HGP6	Streptococcus_phage	4.2e-58	90.8
ARC48877.1\|1087339_1087705_-	helix-turn-helix domain-containing protein	O48389	Streptococcus_phage	3.7e-51	87.6
ARC48878.1\|1087873_1088077_+	XRE family transcriptional regulator	A0A191KC33	Streptococcus_virus	5.9e-27	89.6
ARC48879.1\|1088137_1088881_+	phage antirepressor Ant	A0A2P0VK28	Streptococcus_phage	1.2e-101	75.1
ARC48880.1\|1089278_1089605_+	transcriptional regulator	K4JW96	Streptococcus_phage	1.1e-25	59.8
ARC48881.1\|1089873_1090056_+	hypothetical protein	NA	NA	NA	NA
ARC48882.1\|1090468_1091881_+	hypothetical protein	F8HGQ4	Streptococcus_phage	5.9e-89	50.1
ARC48883.1\|1091886_1092207_+	hypothetical protein	A0A2H4J2X0	uncultured_Caudovirales_phage	2.5e-35	71.7
ARC48884.1\|1092242_1092425_+	hypothetical protein	Q708Q3	Streptococcus_phage	1.3e-09	61.5
ARC48886.1\|1093494_1094466_+	DUF1351 domain-containing protein	A0A2I6QQU5	Streptococcus_phage	1.1e-131	81.1
ARC48887.1\|1094462_1094966_+	single-stranded DNA-binding protein	A0A2H4J1H8	uncultured_Caudovirales_phage	2.1e-81	90.4
ARC48888.1\|1094974_1095436_+	RusA family crossover junction endodeoxyribonuclease	A0A2H4J7B7	uncultured_Caudovirales_phage	5.2e-79	92.8
ARC48889.1\|1095432_1095669_+	hypothetical protein	A0A2H4J4H9	uncultured_Caudovirales_phage	5.5e-32	82.1
ARC49826.1\|1095986_1096493_+	DUF1642 domain-containing protein	A0A1S5PS22	Streptococcus_phage	1.7e-43	49.7
ARC48890.1\|1096768_1097077_+	DUF1372 domain-containing protein	A0A286QMU5	Streptococcus_phage	6.0e-39	88.0
ARC49827.1\|1097079_1097784_+	hypothetical protein	A0A2H4IZZ3	uncultured_Caudovirales_phage	4.4e-93	72.1
ARC48891.1\|1098523_1098940_+	autolysin	C5IUI9	Streptococcus_phage	3.8e-68	92.0
ARC49828.1\|1099075_1099564_+\|terminase	terminase small subunit	L0P3M6	Streptococcus_phage	1.1e-53	74.0
AVH84117.1\|1099550_1100855_+\|terminase	PBSX family phage terminase large subunit	A0A286QNX6	Streptococcus_phage	1.0e-236	91.0
ARC48892.2\|1102382_1103603_+\|capsid	capsid protein	A0A286QMS2	Streptococcus_phage	2.4e-187	78.4
ARC48893.1\|1103692_1104268_+	scaffolding protein	A0A2H4JBH4	uncultured_Caudovirales_phage	1.0e-63	69.9
ARC48894.1\|1104290_1105112_+\|capsid	N4-gp56 family major capsid protein	A0A2H4JBI0	uncultured_Caudovirales_phage	1.7e-117	76.3
ARC49829.1\|1105685_1106027_+\|capsid	minor capsid protein	A0A286QMS6	Streptococcus_phage	6.0e-56	93.7
ARC48895.1\|1106026_1106461_+\|capsid	capsid protein	A0A286QMS1	Streptococcus_phage	2.2e-55	89.0
ARC48897.1\|1107441_1107837_+	hypothetical protein	A0A286QNZ4	Streptococcus_phage	3.5e-39	70.1
ARC48898.1\|1107805_1108468_+	hypothetical protein	A0A286QMS7	Streptococcus_phage	8.3e-102	84.1

DBSCAN-SWA_6

1113085 : 1165512

Streptococcus_phage(71.11%)

capsid,protease,tail,terminase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC48899.1\|1113085_1113814_+	hypothetical protein	A0A286QMT6	Streptococcus_phage	9.7e-112	80.2
ARC48900.1\|1113810_1115646_+	hypothetical protein	A0A1L2JXU3	Streptococcus_phage	1.6e-171	58.6
ARC48901.1\|1115648_1118141_+	hypothetical protein	A0A286QMM0	Streptococcus_phage	4.7e-41	55.9
ARC48902.1\|1118184_1118619_+\|holin	holin	F8HGP0	Streptococcus_phage	3.2e-62	87.5
ARC48903.1\|1118611_1118842_+\|holin	phage holin	A0A2I6QR05	Streptococcus_phage	2.2e-30	90.8
ARC48904.1\|1118846_1119299_+	hypothetical protein	A0A2I6QR28	Streptococcus_phage	1.1e-70	89.3
ARC48905.1\|1119312_1119642_+	hypothetical protein	A0A2H4J011	uncultured_Caudovirales_phage	1.4e-41	84.3
ARC48906.1\|1119646_1119919_+	hypothetical protein	A0A2H4J827	uncultured_Caudovirales_phage	4.5e-22	71.6
ARC48907.1\|1119937_1121323_+	CHAP domain-containing protein	A0A286QS50	Streptococcus_phage	9.4e-249	89.6
ARC49830.1\|1121999_1123436_-	recombinase family protein	A0A2H4J6X5	uncultured_Caudovirales_phage	1.0e-261	95.6
ARC49831.1\|1123586_1124171_-	hypothetical protein	A0A2H4J009	uncultured_Caudovirales_phage	6.4e-74	95.9
ARC48908.1\|1124185_1124563_-	ImmA/IrrE family metallo-endopeptidase	F8HGP6	Streptococcus_phage	4.2e-58	90.8
ARC48909.1\|1124569_1124935_-	helix-turn-helix domain-containing protein	O48389	Streptococcus_phage	3.7e-51	87.6
ARC48910.1\|1125103_1125307_+	XRE family transcriptional regulator	A0A191KC33	Streptococcus_virus	5.9e-27	89.6
ARC48911.1\|1125367_1126111_+	phage antirepressor Ant	A0A2P0VK28	Streptococcus_phage	1.2e-101	75.1
ARC48912.1\|1126508_1126835_+	transcriptional regulator	K4JW96	Streptococcus_phage	1.1e-25	59.8
ARC48913.1\|1127103_1127286_+	hypothetical protein	NA	NA	NA	NA
ARC48914.1\|1127698_1129111_+	hypothetical protein	F8HGQ4	Streptococcus_phage	5.9e-89	50.1
ARC48915.1\|1129116_1129437_+	hypothetical protein	A0A2H4J2X0	uncultured_Caudovirales_phage	2.5e-35	71.7
ARC48916.1\|1129472_1129655_+	hypothetical protein	Q708Q3	Streptococcus_phage	1.3e-09	61.5
ARC48918.1\|1130724_1131696_+	DUF1351 domain-containing protein	A0A2I6QQU5	Streptococcus_phage	1.1e-131	81.1
ARC48919.1\|1131692_1132196_+	single-stranded DNA-binding protein	A0A2H4J1H8	uncultured_Caudovirales_phage	2.1e-81	90.4
ARC48920.1\|1132204_1132666_+	RusA family crossover junction endodeoxyribonuclease	A0A2H4J7B7	uncultured_Caudovirales_phage	5.2e-79	92.8
ARC48921.1\|1132662_1132899_+	hypothetical protein	A0A2H4J4H9	uncultured_Caudovirales_phage	5.5e-32	82.1
ARC49832.1\|1133216_1133723_+	DUF1642 domain-containing protein	A0A1S5PS22	Streptococcus_phage	1.7e-43	49.7
ARC48922.1\|1133998_1134307_+	DUF1372 domain-containing protein	A0A286QMU5	Streptococcus_phage	6.0e-39	88.0
ARC49833.1\|1134309_1135014_+	hypothetical protein	A0A2H4IZZ3	uncultured_Caudovirales_phage	4.4e-93	72.1
ARC48923.1\|1135752_1136169_+	autolysin	C5IUI9	Streptococcus_phage	3.8e-68	92.0
ARC49834.1\|1136304_1136793_+\|terminase	terminase small subunit	L0P3M6	Streptococcus_phage	1.1e-53	74.0
ARC48924.1\|1141514_1142336_+\|capsid	N4-gp56 family major capsid protein	A0A2H4JBI0	uncultured_Caudovirales_phage	1.7e-117	76.3
ARC48925.1\|1142516_1142924_+	hypothetical protein	C5IUJ7	Streptococcus_phage	1.8e-35	58.1
ARC49835.1\|1142910_1143252_+\|capsid	minor capsid protein	A0A286QMS6	Streptococcus_phage	6.0e-56	93.7
AVH84118.1\|1143251_1143611_+\|capsid	capsid protein	A0A286QMS1	Streptococcus_phage	8.3e-56	89.8
ARC48926.1\|1143610_1144015_+\|capsid	capsid protein	A0A286QML6	Streptococcus_phage	3.1e-67	94.8
ARC48928.1\|1144668_1145031_+	hypothetical protein	A0A286QNZ4	Streptococcus_phage	1.1e-39	70.3
ARC48929.1\|1145033_1145696_+	hypothetical protein	A0A286QMS7	Streptococcus_phage	8.3e-102	84.1
ARC48930.1\|1145712_1150320_+\|tail	phage tail protein	C5IUK3	Streptococcus_phage	2.0e-263	91.3
ARC48931.1\|1150316_1151045_+	hypothetical protein	A0A286QMT6	Streptococcus_phage	9.7e-112	80.2
ARC48932.1\|1151041_1152877_+	hypothetical protein	A0A1L2JXU3	Streptococcus_phage	1.6e-171	58.6
ARC48933.1\|1152879_1155372_+	hypothetical protein	A0A286QMM0	Streptococcus_phage	4.7e-41	55.9
ARC48934.1\|1155415_1155850_+\|holin	holin	F8HGP0	Streptococcus_phage	3.2e-62	87.5
ARC48935.1\|1155842_1156073_+\|holin	phage holin	A0A2I6QR05	Streptococcus_phage	2.2e-30	90.8
ARC48936.1\|1156077_1156530_+	hypothetical protein	A0A2I6QR28	Streptococcus_phage	1.1e-70	89.3
ARC48937.1\|1156543_1156873_+	hypothetical protein	A0A2H4J011	uncultured_Caudovirales_phage	1.4e-41	84.3
ARC48938.1\|1156877_1157150_+	hypothetical protein	A0A2H4J827	uncultured_Caudovirales_phage	4.5e-22	71.6
ARC48939.1\|1157168_1158554_+	CHAP domain-containing protein	A0A286QS50	Streptococcus_phage	9.4e-249	89.6
ARC48940.1\|1159174_1159477_+	competence protein ComGC	NA	NA	NA	NA
ARC48941.1\|1159502_1159865_+	competence protein	NA	NA	NA	NA
ARC48942.1\|1159836_1160127_+	competence protein ComGE	NA	NA	NA	NA
ARC48943.1\|1160113_1160551_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
ARC48944.1\|1160528_1160846_+	competence protein ComG	NA	NA	NA	NA
ARC48945.1\|1160890_1161847_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
ARC48946.1\|1161903_1163097_+	acetate kinase	NA	NA	NA	NA
ARC48947.1\|1163347_1163545_+	transcriptional regulator	NA	NA	NA	NA
ARC48948.1\|1163556_1164213_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
ARC48949.1\|1164290_1164737_+\|protease	CAAX protease	NA	NA	NA	NA
ARC48950.1\|1164849_1165512_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

1522571 : 1532814

Streptococcus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC49264.1\|1522571_1523471_+	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	32.8
ARC49265.1\|1523514_1523910_-	lactoylglutathione lyase	NA	NA	NA	NA
ARC49266.1\|1524025_1524919_+	ROK family protein	NA	NA	NA	NA
ARC49267.1\|1525073_1526168_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.9e-172	81.5
ARC49268.1\|1526180_1526738_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	5.4e-54	56.7
ARC49269.1\|1526756_1527935_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	3.0e-179	79.8
ARC49270.1\|1527989_1528484_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-35	45.1
ARC49271.1\|1528518_1528872_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.1e-39	65.8
ARC49272.1\|1529152_1529527_+	murein hydrolase regulator LrgA	NA	NA	NA	NA
ARC49273.1\|1529519_1530215_+	LrgB family protein	NA	NA	NA	NA
ARC49274.1\|1530300_1530861_+	DNA gyrase subunit B	NA	NA	NA	NA
ARC49275.1\|1530861_1532814_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	7.5e-143	45.4

DBSCAN-SWA_8

1792338 : 1815132

Streptococcus_phage(90.48%)

integrase,transposase

attL 1785636:1785655|attR 1816753:1816772

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1785636:1785655	attL	NA	NA	NA	NA
ARC49406.1\|1792338_1792653_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
ARC49407.1\|1792668_1793055_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
ARC49408.1\|1793083_1794469_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
ARC49409.1\|1794471_1794624_+	conjugal transfer protein	NA	NA	NA	NA
ARC49410.1\|1794646_1795852_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
ARC49411.1\|1795894_1796116_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
ARC49412.1\|1796232_1796730_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
ARC49413.1\|1796704_1797211_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
ARC49414.1\|1797194_1799642_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
ARC49415.1\|1799644_1801822_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
ARC49416.1\|1801818_1802820_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
ARC49417.1\|1802816_1803749_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
ARC49418.2\|1804023_1804110_+	tetracycline resistance protein	NA	NA	NA	NA
ARC49419.1\|1804125_1806045_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
ARC49420.2\|1806145_1806331_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
ARC49421.1\|1806943_1807027_+	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
ARC49422.1\|1807151_1807889_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
AVH84132.1\|1807893_1808025_+	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
ARC49423.1\|1808243_1808798_+	resolvase	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
ARC49424.1\|1808801_1811720_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
AVH84146.1\|1812219_1812291_+	hypothetical protein	NA	NA	NA	NA
ARC49425.1\|1812519_1812942_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
ARC49426.1\|1812938_1813169_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
ARC49427.1\|1813394_1813646_-	hypothetical protein	NA	NA	NA	NA
ARC49428.1\|1813629_1813833_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
ARC49429.1\|1813914_1815132_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
1816753:1816772	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2047027 : 2057690

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARC49630.1\|2047027_2048836_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	2.5e-100	39.4
ARC49631.1\|2048950_2049283_+	alkylphosphonate utilization protein	NA	NA	NA	NA
ARC49632.1\|2049483_2050125_+	amino acid ABC transporter permease	NA	NA	NA	NA
ARC49633.1\|2050133_2050763_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.8e-32	40.2
ARC49634.1\|2050775_2051627_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
ARC49635.1\|2051740_2053156_+	DNA polymerase	M1Q231	Streptococcus_phage	6.1e-195	70.7
ARC49636.1\|2053152_2053530_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	9.1e-21	45.8
ARC49637.1\|2053507_2053789_+	hypothetical protein	M1PG86	Streptococcus_phage	1.6e-22	58.4
ARC49638.1\|2053950_2054970_+	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	1.3e-26	25.2
ARC49639.1\|2055253_2055838_+	N-acetyltransferase	NA	NA	NA	NA
ARC49640.1\|2056127_2057690_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.4e-19	30.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP020451

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection