CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
CP016708	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109B, complete sequence	0 crisprs	NA	1
CP015907	Lactococcus lactis subsp. cremoris strain UC109 chromosome, complete genome	1 crisprs	cas3,DEDDh,WYL,csa3,DinG	15
CP016709	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109C, complete sequence	0 crisprs	NA	0
CP016710	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109D, complete sequence	0 crisprs	NA	0
CP016707	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109A, complete sequence	0 crisprs	NA	2
CP016712	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109F, complete sequence	0 crisprs	NA	0
CP016711	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109E, complete sequence	0 crisprs	NA	0
CP034576	Lactococcus lactis subsp. cremoris strain UC109 plasmid pUC109G, complete sequence	0 crisprs	NA	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12579 : 38118

Lactococcus_phage(28.57%)

transposase,integrase

attL 28209:28226|attR 42794:42811

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE04812.1\|12579_13803_+\|transposase	transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
ARE04813.1\|13814_14573_+\|transposase	transposase	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
ARE04814.1\|14621_15374_-	hypothetical protein	NA	NA	NA	NA
ARE04815.1\|15399_15813_-	hypothetical protein	NA	NA	NA	NA
ARE04816.1\|15910_16186_-	hypothetical protein	NA	NA	NA	NA
ARE04817.1\|16200_18036_-	conjugal transfer protein TraG	NA	NA	NA	NA
ARE04818.1\|18050_18542_-	hypothetical protein	NA	NA	NA	NA
ARE04819.1\|18552_18957_-	hypothetical protein	NA	NA	NA	NA
ARE04820.1\|19036_19237_-	hypothetical protein	NA	NA	NA	NA
ARE04821.1\|19359_19554_-	hypothetical protein	NA	NA	NA	NA
ARE04822.1\|19612_19891_-	hypothetical protein	NA	NA	NA	NA
ARE04823.1\|20387_20672_+	hypothetical protein	NA	NA	NA	NA
ARE04824.1\|20695_21283_-	hypothetical protein	NA	NA	NA	NA
ARE04825.1\|21416_22097_+	Transposase	A0A1X9I6C6	Streptococcus_phage	5.0e-110	84.1
ARE04826.1\|22109_22373_-	DNA-binding protein	A0A1S5SAF1	Streptococcus_phage	1.8e-23	67.6
ARE04827.1\|22481_23207_-	ABC transporter permease	NA	NA	NA	NA
ARE04828.1\|23206_23956_-	ABC transporter permease	NA	NA	NA	NA
ARE04829.1\|23961_24873_-	ABC-type multidrug transport system ATPase component	A0A2H4PQG7	Staphylococcus_phage	4.4e-45	45.7
ARE04830.1\|25060_25951_-	Transposase	NA	NA	NA	NA
ARE04831.1\|26102_26801_+	DNA-binding response regulator OmpR family	W8CYM9	Bacillus_phage	3.9e-33	37.0
ARE04832.1\|26797_28168_+	two-component sensor histidine kinase	NA	NA	NA	NA
28209:28226	attL	NA	NA	NA	NA
ARE04833.1\|28281_28962_+	Transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-111	85.4
ARE04834.1\|29252_29597_+	hypothetical protein	NA	NA	NA	NA
ARE04835.1\|29649_30204_-	site-specific recombinase	A0A286S1P7	Klebsiella_phage	1.8e-41	49.7
ARE04836.1\|30493_30820_-\|integrase	integrase	Q6J1X2	Lactobacillus_phage	1.5e-16	50.5
ARE04837.1\|30863_32087_+\|integrase	integrase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
ARE04838.1\|32098_32857_+\|transposase	transposase	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
ARE04839.1\|32905_33502_-	Transposase	A0A1P8CWQ3	Bacillus_phage	9.3e-28	39.5
ARE04840.1\|33513_33774_-	Transposase	NA	NA	NA	NA
ARE04841.1\|33810_34182_-\|transposase	transposase	NA	NA	NA	NA
ARE04842.1\|34425_35262_+	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	1.9e-74	50.5
ARE04843.1\|35741_36902_+	permease, major facilitator superfamily	NA	NA	NA	NA
ARE04844.1\|37231_37654_+	selenium binding protein	NA	NA	NA	NA
ARE04845.1\|37650_38118_-\|integrase	integrase	A0A0A8WF08	Clostridium_phage	9.2e-15	35.9
42794:42811	attR	NA	NA	NA	NA

DBSCAN-SWA_2

50965 : 62452

Lactococcus_phage(44.44%)

integrase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE04864.1\|50965_51646_+	Transposase	A0A1X9I6C6	Streptococcus_phage	4.4e-106	81.9
ARE04865.1\|51837_52176_+	membrane protein	NA	NA	NA	NA
ARE04866.1\|52865_53096_-	hypothetical protein	NA	NA	NA	NA
ARE04867.1\|53145_53442_-	DNA-directed DNA polymerase	NA	NA	NA	NA
ARE04868.1\|53753_54125_+	Transposase	NA	NA	NA	NA
ARE04869.1\|54121_54940_+	Transposase	A0A1B1P773	Bacillus_phage	1.4e-53	43.3
ARE04870.1\|55013_55304_+	Transposase	NA	NA	NA	NA
ARE04871.1\|55321_56161_+	Transposase	U5P429	Shigella_phage	1.6e-46	41.0
ARE04872.1\|56608_56809_-	cold-shock DNA-binding protein family	Q9AZD3	Lactococcus_phage	9.6e-30	97.0
ARE04873.1\|57085_57286_-	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	1.6e-13	54.7
ARE04874.1\|57416_57617_-\|bacteriocin	bacteriocin	Q9AZK6	Lactococcus_phage	2.8e-05	51.9
ARE04875.1\|57756_57966_+	histidine kinase	NA	NA	NA	NA
ARE04876.1\|58595_59276_+	Transposase	A0A1X9I6C6	Streptococcus_phage	4.4e-106	81.9
ARE04877.1\|59303_59642_+\|integrase	integrase	NA	NA	NA	NA
ARE04878.1\|59673_60006_-	Type I restriction-modification system, restriction subunit R	NA	NA	NA	NA
ARE04879.1\|60645_62112_+	DNA polymerase V subunit UmuC	Q6DMX4	Streptococcus_phage	7.7e-124	51.3
ARE04880.1\|62101_62452_+	hypothetical protein	A0A182BQ76	Lactococcus_phage	2.3e-10	75.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP016708

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

41110 : 47681

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE04923.1\|41110_41407_+	hypothetical protein	A0A1S5SEW3	Streptococcus_phage	4.2e-05	39.3
ARE04924.1\|41441_41663_+	Transcriptional regulator xre family	NA	NA	NA	NA
ARE04925.1\|42012_42567_-	Site-specific recombinase, DNA invertase Pin related protein	A0A0A7NPV4	Enterobacteria_phage	3.6e-42	50.6
ARE04926.1\|43052_43718_-	Alpha-acetolactate decarboxylase	NA	NA	NA	NA
ARE04927.1\|43884_44565_+	Transposase	A0A1X9I6C6	Streptococcus_phage	5.8e-127	99.1
ARE04928.1\|44641_45478_-	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	4.1e-74	50.5
ARE04929.1\|45765_46101_+	peptide methionine sulfoxide reductase	NA	NA	NA	NA
ARE04930.1\|46295_46574_+	hypothetical protein	X2KQX9	Campylobacter_phage	7.2e-07	46.0
ARE04931.1\|46622_47078_+	hypothetical protein	NA	NA	NA	NA
ARE04932.1\|47081_47681_+	resolvase	G8I4U3	Mycobacterium_phage	2.5e-12	41.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. CP015907

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP015907_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP015907_1

2101731-2101826

Orphan

Consensus_repeat	Method
TCTTCCTCAATCTTCCCAATTCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP015907_1

>merge|CP015907|1|2101731-2101826|CRISPRCasFinder
TTTGCCAGAATCTTCCTCAATCTTCCCAATTCTTTTAAAATAAACATTTACGCAAGTTATACTTAGTAATATTCTTCCTCAATTTTCCCAATTCTT

>CP015907|1|1|2101731-2101826|CRISPRCasFinder
TTTGCCAGAATCTTCCTCAATCTT	CCCAATTCTTTTAAAATAAACATTTACGCAAGTTATACTTAGTAATAT
TCTTCCTCAATTTTCCCAATTCTT

Protein	Signature genes	Signature genes Name	Protein_function
CP015907.1\|ARE06920.1\|2110965_2111676_+\|Glutamine-amidotransferase-class-I	unknown	unknown	gnl\|CDD\|224982
CP015907.1\|ARE06921.1\|2111825_2112668_+\|amino-acid-ABC-transporter-substrate-binding-protein-PAAT-family	unknown	unknown	gnl\|CDD\|270428
CP015907.1\|ARE06916.1\|2105573_2105903_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227933
CP015907.1\|ARE06910.1\|2096207_2097539_-\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|234757
CP015907.1\|ARE06912.1\|2098555_2101648_-\|DNA/RNA-helicase-SWF/SNF-family	unknown	unknown	gnl\|CDD\|350770
CP015907.1\|ARE06919.1\|2108672_2110964_+\|Xaa-Pro-dipeptidyl-peptidase	unknown	unknown	gnl\|CDD\|235435
CP015907.1\|ARE06922.1\|2112756_2114079_-\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|180907
CP015907.1\|ARE06914.1\|2103303_2104260_-\|Beta-lactamase-family-protein	unknown	unknown	gnl\|CDD\|365903
CP015907.1\|ARE06917.1\|2106813_2107596_+\|metal-dependent-membrane-protease	unknown	unknown	gnl\|CDD\|376806
CP015907.1\|ARE06906.1\|2091288_2092521_-\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
CP015907.1\|ARE06903.1\|2087384_2088329_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
CP015907.1\|ARE06918.1\|2107631_2108501_-\|Glycerol-uptake-facilitator-related-permease-(Major-Intrinsic-Protein-Family)	unknown	unknown	gnl\|CDD\|223653
CP015907.1\|ARE06908.1\|2093827_2095522_-\|arginyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|183534
CP015907.1\|ARE06911.1\|2097739_2098339_-\|hypothetical-protein	unknown	unknown	unknown
CP015907.1\|ARE06907.1\|2092735_2093590_+\|transposase-for-insertion-sequence-element-IS982B	unknown	unknown	gnl\|CDD\|372648
CP015907.1\|ARE06913.1\|2101856_2102498_-\|Integrase	unknown	unknown	gnl\|CDD\|271189
CP015907.1\|ARE06915.1\|2104332_2105112_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373100
CP015907.1\|ARE06909.1\|2095589_2096048_+\|Arginine-operon-repressor	unknown	unknown	gnl\|CDD\|130592
CP015907.1\|ARE06904.1\|2088346_2089927_-\|arginine/ornithine-antiporter	unknown	unknown	gnl\|CDD\|163522
CP015907.1\|ARE06905.1\|2090058_2091123_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179366

Protein	Function_ID	Function_description	E-value
CP015907.1\|ARE06920.1\|2110965_2111676_+\|Glutamine-amidotransferase-class-I	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	1.98467e-101
CP015907.1\|ARE06921.1\|2111825_2112668_+\|amino-acid-ABC-transporter-substrate-binding-protein-PAAT-family	gnl\|CDD\|270428	cd13710, PBP2_TcyK, Substrate binding domain of an ABC transporter TcyJKLMN; the type 2 periplasmic binding protein fold. This group contains periplasmic cystine-binding domain (TcyK) of an ATP-binding cassette transporter from Bacillus subtilus and its closely related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.80736e-84
CP015907.1\|ARE06916.1\|2105573_2105903_-\|hypothetical-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	1.81818e-27
CP015907.1\|ARE06910.1\|2096207_2097539_-\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|234757	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional.	0
CP015907.1\|ARE06912.1\|2098555_2101648_-\|DNA/RNA-helicase-SWF/SNF-family	gnl\|CDD\|350770	cd18012, DEXQc_arch_SWI2_SNF2, DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins. Proteins belonging to SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. The Snf2 family comprises a large group of ATP-hydrolyzing proteins that are ubiquitous in eukaryotes, but also present in eubacteria and archaea. Archaeal SWI2 and SNF2 are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.26854e-94
CP015907.1\|ARE06919.1\|2108672_2110964_+\|Xaa-Pro-dipeptidyl-peptidase	gnl\|CDD\|235435	PRK05371, PRK05371, x-prolyl-dipeptidyl aminopeptidase; Provisional.	0
CP015907.1\|ARE06922.1\|2112756_2114079_-\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|180907	PRK07251, PRK07251, FAD-containing oxidoreductase.	1.09567e-150
CP015907.1\|ARE06914.1\|2103303_2104260_-\|Beta-lactamase-family-protein	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.4174e-51
CP015907.1\|ARE06906.1\|2091288_2092521_-\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
CP015907.1\|ARE06903.1\|2087384_2088329_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	7.27953e-178
CP015907.1\|ARE06918.1\|2107631_2108501_-\|Glycerol-uptake-facilitator-related-permease-(Major-Intrinsic-Protein-Family)	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	2.51202e-67
CP015907.1\|ARE06908.1\|2093827_2095522_-\|arginyl-tRNA-synthetase	gnl\|CDD\|183534	PRK12451, PRK12451, arginyl-tRNA synthetase; Reviewed.	0
CP015907.1\|ARE06917.1\|2106813_2107596_+\|metal-dependent-membrane-protease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.89843e-08
CP015907.1\|ARE06907.1\|2092735_2093590_+\|transposase-for-insertion-sequence-element-IS982B	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.47425e-25
CP015907.1\|ARE06913.1\|2101856_2102498_-\|Integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.384e-11
CP015907.1\|ARE06915.1\|2104332_2105112_-\|hypothetical-protein	gnl\|CDD\|373100	pfam14507, CppA_C, CppA C-terminal. This is the C-terminal domain of the CppA protein found in species of Streptococcus. CppA is a putative C3-glycoprotein degrading proteinase, involved in pathogenicity. It is often found associated with pfam14506.	1.10613e-24
CP015907.1\|ARE06909.1\|2095589_2096048_+\|Arginine-operon-repressor	gnl\|CDD\|130592	TIGR01529, Arginine_repressor., arginine repressor. This model includes most members of the arginine-responsive transcriptional regulator family ArgR. This hexameric protein binds DNA at its amino end to repress arginine biosyntheis or activate arginine catabolism. Some species have several ArgR paralogs. In a neighbor-joining tree, some of these paralogous sequences show long branches and differ significantly in an otherwise well-conserved C-terminal region motif GT[VIL][AC]GDDT. These paralogs are excluded from the seed and score in the gray zone of this model, between trusted and noise cutoffs. [Amino acid biosynthesis, Glutamate family, Regulatory functions, DNA interactions].	8.41328e-60
CP015907.1\|ARE06904.1\|2088346_2089927_-\|arginine/ornithine-antiporter	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	4.25473e-157
CP015907.1\|ARE06905.1\|2090058_2091123_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0

>CP015907.1|ARE06912.1|2098555_2101648_-|DNA/RNA-helicase-SWF/SNF-family
MPARVRSEGIALYAKGFLNDPIETDLKLTAEIDGEEVSYDLDGAQDSCTCSIFQQNHRYCKHIAAIEEYLKNQDKGSLETKDKETKGAERGLYNENIAFLDAVNGETQLNFSTDQYSIEVQIEDNSQLYDYFSMDYFLYFDLKLKSKNLGRSYVIKDIPYFLRALKNYSQYSLGSLHYIDLFFDNFDEASQEFLSFLLKIDGKSDEALTKSLYIKNGRYLNIPFLFLEEAMDLVSALEVYQLKIIGRTVNYFTFIPLDNDSEIFKFKVESQQDYIELSLFSEDYHNFYDYSLLYDNNVFYKLSQEQRRLLLVLDKQFAQKSKIKFSYSEKDKLAQALQQLSTLGKIEAPEHFVVKPFDAKFTFDLLDEKTLSLAMKFDYGTFSIDSFHDLETLEFSRDLRKEQKIFALMERLQFAKAFNSTLEITEHLSENFFLKILPSFQKLGQIELSPTLRNMRMDEVPEIHIDSQGGLLDISFNIPHVEDGEFANVIAKLQENAEFYISESGKFYHFNEKFDRLKAALHELDDQFVIQGSSLHVNINRSFQISKIFEKISGASFSEKFKSLYQHLTHPEEFPYEKPEHIKASLRSYQETGVRWMSMLSHYNLGGILADDMGLGKTVQAITFILSNLKKDESVLITAPASLTYNWASEFEKFTDEIDFVVIDGNKADRTKEIQENHQIYITSYGSFLKDFEDYQDKKLNYLLLDEAQVVKNYSSKTNKSLSALNVEHTFALSGTPLENRIEEIWAIFQVVMPGFLPKREKFNKMEPSVISRLIQPFIMRRKKEDVLEELPEKMEITVYNQLADDQKVIYLAQLELMQKQVLEMDNAALSRSRIEILAGITRLRQICNTPALFMDDYKGSSGKLERLRELLAQIKDSGHRPLIFSQFTKVFPHIEKLMEEQEMTAYKLTGSTPIKDRLSMVQAFNAGSRDAFLVSLKAGGVGLNLTSADVVILVDLWWNPAVEEQAIARAHRMGQKNTVEVIRLITQGTIEEKIMEIQERKKDLIANVLEGDTVDKVLSEAEIREILGV
>CP015907.1|ARE06911.1|2097739_2098339_-|hypothetical-protein
MVERRVVFPVIGDDEVLQKDTRVIFTNQQLLTRNPSLQDEASIETSKSKTDAKRPESFKPYKAKTSFSTQHRPLNSNHAGVSSYDKMPKKTSVDESKERAKRAAATLPKPPKQYVSPLERDKEDLTVRRSTSAILNKRPSTNDNPIRVMKKQGMNVSDAVAKNGSGMKKATPHGGAANDTQKGSYFENKRKNIFDRGIV
>CP015907.1|ARE06910.1|2096207_2097539_-|UDP-N-acetylmuramate--L-alanine-ligase
MEKTYHFTGIKGSGMSALALMLHQMGKNVQGSDSTDYFFTQRGLEQVGVPLLPFDEKNIKPEFELIVGNAFRDDNNVEIAFAHKKGFPFKRYHEFLGHFMEDFTSIGVAGAHGKTSTTGMLAHVMSNIVDTSYLIGDGTGRGNAGSEYFVFESDEYERHFMPYHPEYTIMTNIDFDHPDYFEGIEDVTSAFQDYANNIKKGIFAYGEDVNLRKLSAKAPIYYYGFEANDDYRAENLIRSTRASSFDAYFRGEKIGHFVVPTYGKHNVLNALSVVAVCHNLGLDMTDVADHLLTFRGVKRRFTEKKVGETVIIDDFAHHPTEIEATLDAARQKYPDREIVAVFQPHTFTRTIAFADEFAEVLDHADTVYLAQIYGSAREVDHHEITAQDLADKVRKPAKVIELDNVSPLLDHDRGVYVFMGAGNIQKYEIAFEKLLSQTSTNLQ
>CP015907.1|ARE06909.1|2095589_2096048_+|Arginine-operon-repressor
MKRDKRLEIIKEIVTNNKISTQEELQSLLLERGVEVTQATLSRDIRKLNIIKKRDKGESFYSFLTSGNSKINSDLQLYFYNFVISAKSVGALVVIRTKLGEADVLANALDDERDIRTDILGTIAGADTLLVICASEKAANILTAEIKYILLG
>CP015907.1|ARE06908.1|2093827_2095522_-|arginyl-tRNA-synthetase
MDEKQLVSQALSAAIDGVLGVEQIAAIIEKPKSSDLGDLAFPAFQLAKTLRKSPQIIAGEIAEKIDTKGFEKVIAVGPYVNFFLDKNATASEVIREVLTEGEHYGDANIGEGGNVPIDMSAPNIAKPFSIGHLRSTVIGDSIAKIYEKLGYQPIKINHLGDWGKQFGLLITAYKKYGDEATITANPIDELLKLYVKINAEAKEDPEVDEEGRQWFLKMEQGDEEALRIWKWFSDVSLIEFNRIYGKLGVTFDHFMGESFYSDKMDAIVEDLENKNLLHESKGALIVDLEKYNLNPALIKKTDGATLYITRDLATAAYRKKTFNFVKSLYVVGGEQTNHFKQLKAVLKEAGYDWSDDMVHVPFGMVTQGGKKFSTRKGHVVKLEMALDEAVDRAEKQIEAKNPNLENKEEVAKQVGVGAVKFYDLKTDRNNGYDFDLDEMVSFEGETGPYVQYAHARIQSILRKANRKVNIDNISLVVSDAEAWEIVKALKEFPNIVKRAADNYEPSIIAKYAISLAQAFNKYYAHVRILEDDAQLDGRLALISATSIVLKEALRLLGVAAPENM
>CP015907.1|ARE06907.1|2092735_2093590_+|transposase-for-insertion-sequence-element-IS982B
MTYNSTLPKVFVYLLTTIETLYQTRVPLEVQNRKNVHLATSGCLVIACYLWGVLHFSETLKAKHQLAQSLFPNFLEYSRFVRRCNALLPSIQVIRQAIVFKEVEGMSVSIIDSFPIPLCQPIRNFKSKVLGDYANVGYNATKGQYFYGCKCHALVSESGYVIDYTITPASMADSSMTEEVLSQFGTPTVLGDMGYLGQSLHDRLELKGIDLITPVRKNMKQKKILFPNFSKRRKVIERVFSFLTNLGAERCKSRSPQGFQLKLEMILLAYSLLLNQLNHWNQRL
>CP015907.1|ARE06906.1|2091288_2092521_-|arginine-deiminase
MNNGINVNSEIGKLKSVLLHRPGAEVENITSDTMKQLLFDDIPYLKIAQKEHDFFAQTLRDNGAETVYIENLATEVFEKSSETKEEFLSHLLHEAGYRPGRTYDGLTEYLTSMPTKDMVEKVYAGVRKNELDIKRTALSDMAGSDAENYFYLNPLPNAYFTRDPQASMGVGMTINKMTFPARQPESLITEYVMANHPRFKDTPIWRDRNHTTRIEGGDELILNKTTVAIGVSERTSSKTIQNLAKELFANPLSTFDTVLAVEIPHNHAMMHLDTVFTMINHDQFTVFPGIMDGAGNINVFILRPGQDGEVEIEHLTDLKAALKKVLNLSELDLIECGAGDPIAAPREQWNDGSNTLAIAPGEIVTYDRNYVTVELLKEHGIKVHEILSSELGRGRGGARCMSQPLWREDL
>CP015907.1|ARE06905.1|2090058_2091123_-|ornithine-carbamoyltransferase
MTSPLITKAEVNSVFQGRSLLAEKDFTPDEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGIKESTEDTARVLGSMFDAIERRGFSQKEVEDLAKYSGVPVWNGLTDDWHPTQMIADFMTVKENFGYLKGLTLVYVGDGRNNMANSLIVTGSMLGVNVHIVAPDSLHPSKEVMDIANKFAEKSGAKPLATSNIEEGVKGANIIYSDVWVSMGESNWEERVKLLTPYRITMDMLKMTGNADNGKLIFMHCLPSFHDTETEYGKEIKEKYGLTEMEVTDEVFRSKYARQFEEAENRMHSIKAIMAATLGNLFIPAVPEDFK
>CP015907.1|ARE06904.1|2088346_2089927_-|arginine/ornithine-antiporter
MDAENKKGIGLAALVAIIVSGAIGGGVFNLSNDLATNASPGGVVISWIVIGFGILMLVLSLNHLVVNKPELSGVSDYARAGFGNMVGFISGWGYWLSAWAGNIAFAVLMMTAVDYFFPGVFQAKNGSLTILSVIVVSIVSWGLTLLVMRGVEGAAAINAIVLVAKLIPLFVFVIAGIVTFKAGVFSAHFWQNFVANTNADGVIKSLTWSNMTGGDLFSQVKGSLMVMIWVFVGIEGAAMMGDRAKRKSDAGKASILGLIALLVIYILLSLLPFGFMSQQELANTGQPGLVHILNAMVGGWGGSLMAIGLVISLLGAWLSWTMLPVEATQQLSEQKLLPSWFGKLNDKGAPKNSLLLTQMIVQIFLIVTYFVADAYNVFVYLCTAVIMICYALVGLYLFKLGIQEKKTSNIIIGFIAAAFQILALYYSGWQFVWLSLILYAVGFILYALGKKEYGTKMSTAELIATFILTVLGILAVFGVYGNWLGLQDALGIDGNTLLVAVVPLIVVTFIVYFVVRSDINKKGIKN
>CP015907.1|ARE06903.1|2087384_2088329_-|carbamate-kinase
MVSRIVVALGGNAILTKDPSAAAQKKALEVTAEQLMPLIKDNDRQMVVTHGNGPQVGNLLLQQLGSDSEKNPAMPLDTVGAMTQGEIGFWTVQAFTRAMANNGLERYPVISAVTQTLVDENDPAFKNASKPIGPFYTEEQLPEIKKQFPDWELMEDAGRGYRRVVPSPKPLEIIEAKAFGPILESGSLLIASGGGGIPVIKDGNGYKGVEAVIDKDFSAAKLAEMVGADELLILTAVDNVFVNFNKPNQKKLETVTMAEMKAYIKEGQFAAGSMLPKVEAAMEFVTRTGRPATITSLENLEDFLNNDSGTKIIP
>CP015907.1|ARE06913.1|2101856_2102498_-|Integrase
MEVLLNHMKEFEKTQNTKQEDCVRKRLFIEFTYLNGNRYGEGAGLKFSTVNHGGIWIKDQYSRKSSVKNPINKQTKTLTSRRIKAFENDDTRSKEIIQWFLDHNNSGINDDYIFVRKNGHLLSDDTMNRYLHRFEKQMPDKLSSSFVMHSLRHSYITRRAEAGDTETEIMAKVGHANPNLVHTLYTHVRDTLKFDEQKKFKKQPRLLKIGKSA
>CP015907.1|ARE06914.1|2103303_2104260_-|Beta-lactamase-family-protein
MKNQQEFLAMIEDYLERDVFPGVNFAILEGEEVSEYLFGKAALIPEPIALTPGKKWDLASLTKVIGTGTAVIDLVLAGKLELDAPLQKYYAKFTDSTVSLRQLLTHTSGIDPYIPNRDKLGFFELTEAINQIRVTDDKSFKYTDINFILLGFLLEEYYDESLDYIFNKNIFKNWEMKQTSFGSVENAVPTSQNIPLGTVHDPKAQVLKNHCGSAGLFSTLSDMILFSQAYFREEKYLELLKNYADGAKERSLAWDLPAENNDWLLHTGYTGTFILINPRIKKAVVFLSNRVHLKDNREKWIEERDRLIKFLINHLSLD
>CP015907.1|ARE06915.1|2104332_2105112_-|hypothetical-protein
MSEIINHITAFQPVYRVLHREENLDFYRGVLGFKVLVEEGAMVWLGGHEAKKDRFQLEESPGFHPVEGLKKHGQTVIKANSSEIEQLIVRNLDKIAKIYQGKNGLAFTALSPEAGLFLVSSDSLTDLPALTEINKSEIKLNLDKNFKGLSDFEITAMNLNVADKSIIEFYESVFDLKAIDGKIEFPFVTLTLNVEESEDLTAGTDEVLDLEFLIFMIDKDFDLKAFANQFSEANGTYIDASAKTFFLEVPDHAELWFVK
>CP015907.1|ARE06916.1|2105573_2105903_-|hypothetical-protein
MEFEEFFINNQLMKLIRETVLSIFPEAQERISYGMPAWFNGKTVLIYAQPQKHHLGIYPRPNFIEKHLEVLKQQYECSKGTIKVPYGIEHGELRKLVSDVINWNLTHFT
>CP015907.1|ARE06917.1|2106813_2107596_+|metal-dependent-membrane-protease
MNIEKLQFLAKYRWIIVLILALIFSGLSVSIFHLPFLMTALVLSVIGLIFAYHKSVWLVLFILSNLPMLVSTIFASQHHFSTLDTIIFFIIFIFTIISSYLIARKAELIPKLSWKYFPPLRIILGFVLLFLVSILTGIFAQIFNQSPTTTNQESLNELQKVIPIAVFATQTLAASFLEELVYRVGIFELIFKNQKYFAFLTTMLLFAFMHGPTDVYSWLTYGLMSLVLTGLYAKYRNFYLNMSVHFLWNLFGLVIALMVK
>CP015907.1|ARE06918.1|2107631_2108501_-|Glycerol-uptake-facilitator-related-permease-(Major-Intrinsic-Protein-Family)
MDVTWTVKYITEFVGTALLIIMGNGAVANVELKGTKAHAQSWLIIGWGYGLGVMLPAVAFGNITSQINPAFTLGLAASGLFPWAHVAQYIIAQVLGAMFGQLLIVMVYRPYYLKTQNPNAILGTFSTIDNVDDNSEKTRLGATINGFLNEFLGSFVLFFGAVAATNIFFGSQSITWMTNYLKGQGADVSSSDVMNQIWVQASGASASKMIAHLFLGFLVLGLVVALGGPTGPGLNPARDFGPRLVHSLLPKSVLGEAKGSSKWWYAWVPVLAPILASLAAVALFKMIYL
>CP015907.1|ARE06919.1|2108672_2110964_+|Xaa-Pro-dipeptidyl-peptidase
MRFNHFSIVDKNFDEQLAELDQLGFRWSVFWDEKKILKDFLIQSPSDMTDLQATAELDVIEFLKSSIELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAEMTTENIISAFYYLLCTRRKNGMILVEHWVSEGLLPLDNHYHFFNDKSLATFDSSLLEREVLWVESPVDSEQRGENDLIKIQIIRPKSTEKLPVVMTASPYHLGINDKANDLALHDMNVELEEKTSHEIHVEQKLPQKLSAKAKELPIVDKAPYRFTHGWTYSLNDYFLTRGFASIYVAGVGTRSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANGKVAMTGKSYLGTMAYGAATTGVEGLEVILAEAGISSWYNYYRENGLVRSPGGFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAYFVAKLLDRDLNLNLPPVILQENSKDQVWTMMNDFGANTQIKLPLGKTAVSFAQFDNHYDDETFKKYSKDFNVFKKDLFENKANEAVIDLELPSMLTINGPVELELRLKLNDTKGFLSAQILDFGQKKRLEDKARVKDFKVLDRGRNFMLDDLVELSLVESPYQLITKGFTNLQNQNLLTVSDLKADEWFTIKFELQPTIYHLEKADKLRVILYSTDFEHTVRDNRKVTYEIDLSQSKLIIPIESVKN
>CP015907.1|ARE06920.1|2110965_2111676_+|Glutamine-amidotransferase-class-I
MAIIGILGTPYNTVERSPFWWNKVSYTRQSFIDVFQELGHTVIVLPVDKTENIKNYLPLVDKIVLTGGADVSPYLYGEEPHAQLGTTDPIRDRFELAAIKAALEANKPILGVCRGLQLLNVYFGGTLYQDLSLTSSQIKHLQSPTPQEVPTHHISVEKESSLGFLPENYMVNSFHHQVIKDLGQGLQAIAHGNDGLVEAIENKEKHVLAVQWHPECTWETENFDKKIFEIFANGDI
>CP015907.1|ARE06921.1|2111825_2112668_+|amino-acid-ABC-transporter-substrate-binding-protein-PAAT-family
MKKIKLLTLATLGIASIGLLAACSSKDNSSSKSTDKVTTVTVATSAASVPYEYSENGKMTGFEYDILKAADKDMKDYKFEFKVYEDSAILAALDGGRAQIAANNFGKTKARSEKYLFSYPVRQGIDAIFSTSKENITKISQLAGKTTEIPAGTNYGDMFESWNKNHPDKKIDVKYSQRPLADRLSAIASGQIDFLFASKAPAENLIRQHAITGLVDTVPTDLNKQSEFKTYDYFILDNSQTKLQKDLNAELKKLYENGTLKELSEKYFHDSHIPAADQFK
>CP015907.1|ARE06922.1|2112756_2114079_-|pyridine-nucleotide-disulfide-oxidoreductase
METRHFKNIIIGFGKAGRALAKSLSKNGEEALIIERDQAMYGGTCPNVGCAPSKTLIVAGQKNMNFSEAMTTKYKVREILHNAAYHGAADEALVYVMDGLARFINSKTVEVVNGENVTQVIGERIFINTGATPIIPEIEGIHEAKNVVTSEGAMELSELPKKLVIIGAGYIGLEFAGMFNKFGSEVTILEPHATFLPKEDEDISNEIYKDLVAAGVEIQLGVEIERITDSEVFAGGKIYPADKILIATGRRPNIKDLDLEKADVELSENGYIKVDDDLKTTAQNIWALGDVRGGGQFYYLSTDDFRIVNNQLFGDHSRKLSDRKLVPYSVFISPTLSRIGLDEKQAKEAGVNYRLFKMAAAPIVKAKVVQDTRGLLKALVDPNTDEILGATLYHEDSHEVINLVSLAMKMHTPYQVLRDQIFTHPTMGEGLNDLFQNEVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13887 : 71967

Lactococcus_phage(15.38%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE04978.1\|13887_14454_+\|tRNA	peptidyl-tRNA hydrolase	NA	NA	NA	NA
ARE04979.1\|14454_17943_+	Transcription-repair coupling factor	NA	NA	NA	NA
ARE04980.1\|18259_18529_+	Ribosome-associated heat shock protein	NA	NA	NA	NA
ARE04981.1\|18559_18934_+	Septum formation initiator	NA	NA	NA	NA
ARE04982.1\|18933_19257_+	hypothetical protein	NA	NA	NA	NA
ARE04983.1\|19397_20735_+	beta-lactamase A	NA	NA	NA	NA
ARE04984.1\|20731_22000_+\|tRNA	tRNA(Ile)-lysidine synthetase	NA	NA	NA	NA
ARE04985.1\|21980_22532_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	1.4e-09	29.7
ARE04986.1\|22737_24825_+\|protease	membrane protease FtsH catalytic subunit	G8DDJ2	Micromonas_pusilla_virus	1.6e-106	49.2
ARE04987.1\|25892_27716_+	Phosphotransferase system mannitol-specific IIBC component	NA	NA	NA	NA
ARE04988.1\|27775_29638_+	transcriptional regulator mtl operon mtlR	NA	NA	NA	NA
ARE04989.1\|29709_30438_-\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	6.0e-130	99.2
ARE04990.1\|30382_31693_-\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	3.1e-225	99.7
ARE04991.1\|31915_32347_+	PTS system mannitol-specific IIA component	NA	NA	NA	NA
ARE04992.1\|32495_33662_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
ARE04993.1\|34474_34717_+	hypothetical protein	NA	NA	NA	NA
ARE04994.1\|34810_36433_-	Sulfate transporter	NA	NA	NA	NA
ARE04995.1\|36642_37164_+	GNAT family acetyltransferase	A0A1P8CWJ6	Bacillus_phage	1.0e-30	42.1
ARE04996.1\|37625_38801_+	aromatic amino acid aminotransferase	NA	NA	NA	NA
ARE04997.1\|38898_39654_+	DNA repair protein RecO	NA	NA	NA	NA
ARE04998.1\|39805_41224_-	dihydrolipoamide dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.0e-40	27.0
ARE04999.1\|41442_43029_-	pyruvate dehydrogenase complex E2 component	NA	NA	NA	NA
ARE05000.1\|43021_44002_-	pyruvate dehydrogenase E1 component beta subunit	NA	NA	NA	NA
ARE05001.1\|44004_45129_-	acetoin dehydrogenase complex E1 component alpha subunit	NA	NA	NA	NA
ARE05002.1\|45217_46219_-	lipoate-protein ligase	NA	NA	NA	NA
ARE05003.1\|46411_47266_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	7.8e-12	31.4
ARE05004.1\|47344_48004_-	Metal-dependent phosphohydrolase HD superfamily	A0A1S5XYU7	Kurlavirus	1.2e-15	33.3
ARE05005.1\|48044_48371_-	hypothetical protein	NA	NA	NA	NA
ARE05006.1\|48427_49318_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05007.1\|49470_50496_-\|tRNA	tryptophanyl-tRNA synthetase II	NA	NA	NA	NA
ARE05008.1\|50994_51432_+	osmotically inducible protein C	NA	NA	NA	NA
ARE05009.1\|51593_52907_+	Amino acid permease	NA	NA	NA	NA
ARE05010.1\|52985_53981_-	putative glycerol-3-phosphate acyltransferase PlsX	NA	NA	NA	NA
ARE05011.1\|54083_54896_-	Hydrolase HAD superfamily	NA	NA	NA	NA
ARE05012.1\|55423_57061_-	ATPase component of ABC transporter	A0A2K9L3Z8	Tupanvirus	4.8e-50	25.9
ARE05013.1\|57561_57816_+	hypothetical protein	NA	NA	NA	NA
ARE05014.1\|57934_58759_-	Short chain dehydrogenase	NA	NA	NA	NA
ARE05015.1\|58918_59500_-	Transcriptional regulator	NA	NA	NA	NA
ARE05016.1\|59687_60170_-	hypothetical protein	NA	NA	NA	NA
ARE05017.1\|60426_61707_-	O-acetyl-L-homoserine sulfhydrolase / O-acetyl-L-serine sulfhydrolase	A0A2I2L687	Orpheovirus	2.5e-09	26.5
ARE05018.1\|61959_62793_-	Short-chain dehydrogenase	NA	NA	NA	NA
ARE05019.1\|63141_64032_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05020.1\|64818_64968_-	LSU ribosomal protein L33P	NA	NA	NA	NA
ARE05021.1\|64997_65171_-	LSU ribosomal protein L32P	NA	NA	NA	NA
ARE05022.1\|65532_67314_+	Lead cadmium zinc mercury transporting ATPase	E4ZFI9	Streptococcus_phage	1.7e-64	29.6
ARE05023.1\|68357_69143_-	chromosome partitioning protein parA	NA	NA	NA	NA
ARE05024.1\|69197_70457_-	Chromosome segregation helicase ATPase AAA family	A0A127AWE7	Bacillus_phage	2.5e-91	45.3
ARE05025.1\|70500_70989_-	Acetyltransferase GNAT family	A0A1B2ICF0	Erwinia_phage	1.1e-05	50.9
ARE05026.1\|71076_71967_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_2

82281 : 135446

Bacillus_phage(57.14%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05036.1\|82281_82737_+\|tRNA	D-Tyr-tRNAtyr deacylase	NA	NA	NA	NA
ARE05037.1\|83740_84364_+	hydrolase HAD superfamily	NA	NA	NA	NA
ARE05038.1\|84497_85895_+	amino acid/polyamine/organocation transporter APC superfamily	NA	NA	NA	NA
ARE05039.1\|86064_86706_+	1-Acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
ARE05040.1\|86736_87246_-	Transcriptional regulator	NA	NA	NA	NA
ARE05041.1\|87412_88057_-	Acyl carrier protein phosphodiesterase	NA	NA	NA	NA
ARE05042.1\|88230_90828_+	preprotein translocase subunit SecA	NA	NA	NA	NA
ARE05043.1\|90957_91995_+	phospho-2-dehydro-3-deoxyheptonate aldolase	S4W5F1	Pandoravirus	4.1e-47	36.1
ARE05044.1\|92243_92510_+	phosphocarrier protein HPr	NA	NA	NA	NA
ARE05045.1\|92512_94240_+	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
ARE05046.1\|94414_94723_+	hypothetical protein	NA	NA	NA	NA
ARE05047.1\|94812_95112_-	hypothetical protein	NA	NA	NA	NA
ARE05048.1\|95216_95504_+	Serine hydroxymethyltransferase/Phosphoribosyl-dephospho-CoA transferase family enzyme	NA	NA	NA	NA
ARE05049.1\|95783_96728_-	Alpha/beta hydrolase	NA	NA	NA	NA
ARE05050.1\|98454_98775_+	Membrane cationic transporter	NA	NA	NA	NA
ARE05051.1\|98897_100061_+	multidrug resistance protein	NA	NA	NA	NA
ARE05052.1\|100443_100704_+	Transposase	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE05053.1\|100715_101555_+\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	1.6e-49	41.4
ARE05054.1\|101600_101996_+	membrane protein	NA	NA	NA	NA
ARE05055.1\|102423_103734_+\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	3.1e-225	99.7
ARE05056.1\|103678_104407_+\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	6.0e-130	99.2
ARE05057.1\|106539_107736_+	argininosuccinate synthase	NA	NA	NA	NA
ARE05058.1\|107764_109144_+	argininosuccinate lyase	NA	NA	NA	NA
ARE05059.1\|109160_110357_-	multidrug resistance efflux pump	NA	NA	NA	NA
ARE05060.1\|110549_111125_+	transcriptional regulator TetR family	NA	NA	NA	NA
ARE05061.1\|111281_111635_+	ribonuclease P	NA	NA	NA	NA
ARE05062.1\|111658_112441_+	preprotein translocase subunit	NA	NA	NA	NA
ARE05063.1\|112528_113443_+	RNA-binding protein R3H domain protein	NA	NA	NA	NA
ARE05064.1\|113574_113709_+	LSU ribosomal protein L34P	NA	NA	NA	NA
ARE05065.1\|113885_114797_+	aryl-alcohol dehydrogenase	NA	NA	NA	NA
ARE05066.1\|114866_115181_+	Transcriptional regulator xre family	NA	NA	NA	NA
ARE05067.1\|115243_115924_+	hypothetical protein	NA	NA	NA	NA
ARE05068.1\|116218_116485_+	hypothetical protein	NA	NA	NA	NA
ARE05069.1\|116484_116916_+	RNase H-like ribonuclease	NA	NA	NA	NA
ARE05070.1\|117016_117340_+	hypothetical protein	NA	NA	NA	NA
ARE05071.1\|117369_117921_-	hypothetical protein	NA	NA	NA	NA
ARE05072.1\|118010_118751_-	carbonyl reductase	NA	NA	NA	NA
ARE05073.1\|118770_119082_-	hypothetical protein	NA	NA	NA	NA
ARE05074.1\|119091_119877_-	oxidoreductase dltE	NA	NA	NA	NA
ARE05075.1\|119995_120541_+	transcriptional regulator TetR family	NA	NA	NA	NA
ARE05076.1\|120606_122550_-	1,4-Alpha-glucan branching enzyme	NA	NA	NA	NA
ARE05077.1\|122669_122990_-	hypothetical protein	NA	NA	NA	NA
ARE05078.1\|123812_124073_+\|transposase	IS091 transposase A	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE05079.1\|124084_124924_+\|transposase	IS9810 transposase	A0A1P8CWQ3	Bacillus_phage	9.3e-50	41.4
ARE05080.1\|125052_125592_+	HTH-type transcriptional regulator	NA	NA	NA	NA
ARE05081.1\|126047_130892_+	hypothetical protein	NA	NA	NA	NA
ARE05082.1\|132249_133380_+	Cell surface protein C-terminal membrane anchored	NA	NA	NA	NA
ARE05083.1\|133452_133740_+	hypothetical protein	NA	NA	NA	NA
ARE05084.1\|133791_134499_+	secreted protein	NA	NA	NA	NA
ARE05085.1\|134555_135446_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_3

313903 : 329329

Lactococcus_phage(90.48%)

head,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05252.1\|313903_314227_-	phage hypothetical protein	Q9AZI1	Lactococcus_phage	8.5e-44	86.0
ARE05253.1\|314327_314657_-	phage hypothetical protein	Q9AZE0	Lactococcus_phage	1.7e-52	97.2
ARE05254.1\|314870_315086_-\|head,protease	prohead protease	Q9AZE1	Lactococcus_phage	8.5e-32	95.8
ARE05255.1\|315117_315738_-	phage hypothetical protein	NA	NA	NA	NA
ARE05256.1\|315740_316979_-\|head	major head protein precursor	E9LUQ3	Lactobacillus_phage	3.2e-139	61.1
ARE05257.1\|317319_318954_-	Phage helicase	Q9AZI5	Lactococcus_phage	8.4e-281	88.4
ARE05258.1\|318964_319759_-	phage hypothetical protein	Q9AZI6	Lactococcus_phage	2.5e-145	91.7
ARE05259.1\|319755_320091_-	phage hypothetical protein	Q9AZI7	Lactococcus_phage	2.1e-53	94.4
ARE05260.1\|320077_320272_-	phage hypothetical protein	Q9AZE8	Lactococcus_phage	8.7e-28	98.4
ARE05261.1\|320268_320523_-	phage hypothetical protein	Q9AZE9	Lactococcus_phage	3.6e-37	89.3
ARE05262.1\|320519_320759_-	phage hypothetical protein	Q9AZJ0	Lactococcus_phage	4.4e-37	94.9
ARE05263.1\|320801_321083_-	phage hypothetical protein	Q9AZJ1	Lactococcus_phage	1.0e-45	95.7
ARE05264.1\|321079_321331_-	Transcriptional regulator	Q9AZJ2	Lactococcus_phage	3.3e-35	92.7
ARE05265.1\|321327_321852_-	phage hypothetical protein	Q9AZJ3	Lactococcus_phage	2.8e-60	65.5
ARE05266.1\|321848_322046_-	phage hypothetical protein	Q9AZF2	Lactococcus_phage	1.1e-25	93.5
ARE05267.1\|322061_322283_-	phage hypothetical protein	NA	NA	NA	NA
ARE05268.1\|322468_322645_-	phage hypothetical protein	NA	NA	NA	NA
ARE05269.1\|322908_323598_-	phage hypothetical protein	R9QNB1	Lactococcus_phage	9.5e-93	80.4
ARE05270.1\|323762_323957_-	phage hypothetical protein	R9QNG3	Lactococcus_phage	2.1e-05	43.5
ARE05271.1\|324122_324686_+	phage hypothetical protein	Q9AZN3	Lactococcus_phage	1.6e-16	68.6
ARE05272.1\|324764_324959_+	phage hypothetical protein	Q9AZK1	Lactococcus_phage	1.5e-27	95.3
ARE05273.1\|325253_326150_+	phage hypothetical protein	A3QSC6	Clostridium_virus	1.1e-43	33.3
ARE05274.1\|327406_327571_+	phage hypothetical protein	Q9AZK6	Lactococcus_phage	6.3e-19	92.6
ARE05275.1\|327701_327869_+	phage hypothetical protein	NA	NA	NA	NA
ARE05276.1\|328138_329329_+	Integrase	Q9AZK8	Lactococcus_phage	1.1e-88	46.1

DBSCAN-SWA_4

414537 : 426694

uncultured_virus(30.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05350.1\|414537_414855_+	Thiol-disulfide isomerase and thioredoxin	A0A0K2FIM3	Achromobacter_phage	9.0e-06	31.9
ARE05351.1\|414960_415587_+\|tRNA	phenylalanyl-tRNA synthetase beta chain	NA	NA	NA	NA
ARE05352.1\|415748_417089_+	NADH oxidase H2O-forming	NA	NA	NA	NA
ARE05353.1\|417179_417569_+	single-stranded DNA-binding protein	A0A218MNB4	uncultured_virus	1.3e-22	48.6
ARE05354.1\|417687_417972_+	Co-chaperonin GroES (HSP10)	A0A221S386	uncultured_virus	2.3e-13	43.0
ARE05355.1\|418058_419687_+	Chaperonin GroEL (HSP60 family)	A0A219YK78	uncultured_virus	2.2e-156	56.8
ARE05356.1\|419738_420551_-	ribonuclease Z	A0A0C5AJ83	Bacteriophage	1.5e-33	38.1
ARE05357.1\|420740_422168_-	PAS/PAC sensor signal transduction histidine kinase	W8CYF6	Bacillus_phage	3.9e-32	32.9
ARE05358.1\|422160_422862_-	DNA-binding response regulator OmpR family (Rec-wHTH domains)	W8CYM9	Bacillus_phage	1.2e-42	39.7
ARE05359.1\|423039_423675_+	thymidylate kinase	M1PSC7	Streptococcus_phage	1.6e-73	66.0
ARE05360.1\|423807_424668_+	DNA polymerase III delta prime subunit	M1NSC1	Streptococcus_phage	3.1e-64	44.8
ARE05361.1\|424717_425500_+	Phosphorelay inhibitor	NA	NA	NA	NA
ARE05362.1\|425492_425819_+	Regulator of replication initiation timing	NA	NA	NA	NA
ARE05363.1\|425818_426694_+	methyltransferase	M1PLC5	Streptococcus_phage	5.4e-101	66.3

DBSCAN-SWA_5

505949 : 564907

Bacillus_phage(28.57%)

integrase,transposase,tRNA,protease

attL 555429:555445|attR 566439:566455

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05438.1\|505949_506840_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05439.1\|507132_507510_+	hypothetical protein	NA	NA	NA	NA
ARE05440.1\|507618_508764_+	Cysteine desulfurase / Selenocysteine lyase	NA	NA	NA	NA
ARE05441.1\|508913_509792_+	Gamma-glutamyl-diamino acid-endopeptidase extracellular cell-wall-bound	NA	NA	NA	NA
ARE05442.1\|509848_511498_-	Oligopeptide-binding protein	NA	NA	NA	NA
ARE05443.1\|511681_512614_-	cysteine synthase	A0A1X9I5K7	Streptococcus_phage	4.0e-118	71.1
ARE05444.1\|512832_513918_+	N-acetylglucosaminidase	A0A223LD43	Bacillus_phage	2.1e-09	34.1
ARE05445.1\|513953_514586_-	Metallo-beta-lactamase family protein	A0A1X9I5D3	Streptococcus_phage	1.7e-48	45.3
ARE05446.1\|514586_516668_-	Multimodular transpeptidase-transglycosylase PBP 1A	NA	NA	NA	NA
ARE05447.1\|516654_517296_-	Recombination protein RecU	NA	NA	NA	NA
ARE05448.1\|517376_517901_+	hypothetical protein	NA	NA	NA	NA
ARE05449.1\|518045_518447_+	Arsenate reductase related protein glutaredoxin family	NA	NA	NA	NA
ARE05450.1\|518667_518949_+	hypothetical protein	NA	NA	NA	NA
ARE05451.1\|518914_519694_+	Myo-inositol-1(or 4)-monophosphatase	NA	NA	NA	NA
ARE05452.1\|519788_521069_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
ARE05453.1\|521068_521260_+	hypothetical protein	NA	NA	NA	NA
ARE05454.1\|521338_521896_+\|transposase	IS3/IS911 transposase N-terminal protein	NA	NA	NA	NA
ARE05455.1\|521892_522786_+\|transposase	transposase for insertion sequence IS904H	A0A1B1P773	Bacillus_phage	2.4e-51	42.8
ARE05456.1\|522925_524209_+	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	NA	NA	NA	NA
ARE05457.1\|531068_532982_+	DNA primase	A0A1S5REW9	Helicobacter_phage	1.7e-43	33.5
ARE05458.1\|533058_534402_+	RNA polymerase sigma 70 subunit RpoD	A0A2I7SAT0	Vibrio_phage	7.2e-36	32.6
ARE05459.1\|535409_536789_+	glycerol-3-phosphatase transporter	NA	NA	NA	NA
ARE05460.1\|537822_539088_+	hypothetical protein	NA	NA	NA	NA
ARE05461.1\|539316_539661_+	hypothetical protein	NA	NA	NA	NA
ARE05462.1\|539706_541953_+\|protease	ATP-dependent Clp protease ATP-binding subunit clpE	K4FB40	Cronobacter_phage	2.1e-125	39.7
ARE05463.1\|542078_542549_-	Transcriptional regulator Rrf2 family	NA	NA	NA	NA
ARE05464.1\|542891_543788_+	NAD-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
ARE05465.1\|544011_544647_-\|tRNA	N-formylmethionyl-tRNA deformylase	Q6VSW0	Vibrio_phage	3.8e-11	36.4
ARE05466.1\|544801_545206_+	Bis(5-nucleosyl)-tetraphosphatase (asymmetrical)	NA	NA	NA	NA
ARE05467.1\|545267_547346_+	Excinuclease ABC subunit B	NA	NA	NA	NA
ARE05468.1\|547527_548349_+	amino acid ABC transporter substrate-binding protein PAAT family	NA	NA	NA	NA
ARE05469.1\|548363_548903_+	Acetylornithine deacetylase	NA	NA	NA	NA
ARE05470.1\|548899_549427_+	Acetylornithine deacetylase	NA	NA	NA	NA
ARE05471.1\|549534_549990_-	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	NA	NA	NA	NA
ARE05472.1\|550266_551019_+	Enoyl-[acyl-carrier protein] reductase (NADH)	NA	NA	NA	NA
ARE05473.1\|551204_552167_-	OxaA-like protein precursor	NA	NA	NA	NA
ARE05474.1\|552341_553100_-	alpha-phosphoglucomutase	A0A2P1EM96	Moumouvirus	6.1e-08	25.9
ARE05475.1\|553194_553785_-	hypothetical protein	NA	NA	NA	NA
ARE05476.1\|553801_554338_-	phosphopantothenoylcysteine decarboxylase	Q9J5A8	Fowlpox_virus	6.8e-22	34.9
ARE05477.1\|554330_555026_-	Phosphopantothenoylcysteine synthetase/decarboxylase	Q9HH70	Methanothermobacter_phage	1.7e-17	31.7
ARE05478.1\|555135_555357_-	4-oxalocrotonate tautomerase	NA	NA	NA	NA
555429:555445	attL	NA	NA	NA	NA
ARE05479.1\|557395_557653_-	ribosomal protein S7	NA	NA	NA	NA
ARE05480.1\|557902_558097_+	Acetyltransferase GNAT family	NA	NA	NA	NA
ARE05481.1\|558117_558378_+	Transposase	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE05482.1\|558389_559229_+\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	1.6e-49	41.4
ARE05483.1\|559543_559888_+	hypothetical protein	NA	NA	NA	NA
ARE05484.1\|559917_560748_+	hypothetical protein	NA	NA	NA	NA
ARE05485.1\|560954_561272_+	hypothetical protein	NA	NA	NA	NA
ARE05486.1\|562464_563508_+	plasmid replication initiator protein	NA	NA	NA	NA
ARE05487.1\|563507_563723_+	hypothetical protein	NA	NA	NA	NA
ARE05488.1\|563782_564907_+\|integrase	integrase	A0A1S5SA77	Streptococcus_phage	1.8e-35	29.4
566439:566455	attR	NA	NA	NA	NA

DBSCAN-SWA_6

584998 : 647898

Bacillus_phage(22.22%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05514.1\|584998_585889_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05515.1\|585941_586664_+	hypothetical protein	NA	NA	NA	NA
ARE05516.1\|586695_586971_+	membrane protein	NA	NA	NA	NA
ARE05517.1\|587382_588315_+	Hpr(Ser) kinase	NA	NA	NA	NA
ARE05518.1\|588376_589162_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
ARE05519.1\|589328_589748_+	Methyl-accepting chemotaxis-like domain containing protein	NA	NA	NA	NA
ARE05520.1\|589777_590338_+	hypothetical protein	NA	NA	NA	NA
ARE05521.1\|590471_591890_+	6-phosphogluconate dehydrogenase	E3SJC4	Synechococcus_phage	8.4e-35	33.0
ARE05522.1\|592071_594093_+	Kup system potassium uptake protein	A7K9V6	Acanthocystis_turfacea_chlorella_virus	4.2e-64	33.9
ARE05523.1\|594307_596323_+	Kup system potassium uptake protein	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	3.8e-57	31.6
ARE05524.1\|596375_596546_-	hypothetical protein	NA	NA	NA	NA
ARE05525.1\|596740_597406_+	hypothetical protein	M1Q1P6	Streptococcus_phage	2.3e-19	29.8
ARE05526.1\|597537_598422_+\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
ARE05527.1\|598567_599236_+	hypothetical protein	NA	NA	NA	NA
ARE05528.1\|599400_600303_+\|protease	Membrane protease subunit stomatin/prohibitin family	A0A1V0SL90	Klosneuvirus	1.8e-35	35.2
ARE05529.1\|600551_601217_-	Glycoside hydrolase family 25	A0A1P8BMN5	Lactococcus_phage	3.2e-13	56.9
ARE05530.1\|601675_602023_-	HTH-type transcriptional regulator	A0A182BQC8	Lactococcus_phage	2.0e-43	74.6
ARE05531.1\|602787_603711_+	ribonuclease Z	NA	NA	NA	NA
ARE05532.1\|603703_604405_+	Short-chain dehydrogenase	NA	NA	NA	NA
ARE05533.1\|604577_606806_+	single strand DNA-specific exonuclease	A7KV88	Bacillus_phage	6.7e-79	30.9
ARE05534.1\|606929_607442_+	Adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.3e-32	44.0
ARE05535.1\|607657_608221_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
ARE05536.1\|608359_609997_+	aminodeoxychorismate lyase	NA	NA	NA	NA
ARE05537.1\|610057_610528_+	transcription elongation factor GreA	NA	NA	NA	NA
ARE05538.1\|610722_611094_+	Transposase	NA	NA	NA	NA
ARE05539.1\|611090_611909_+	Transposase	A0A1B1P773	Bacillus_phage	1.4e-53	43.3
ARE05540.1\|611963_612803_-	Transposase	U5P429	Shigella_phage	1.6e-46	41.0
ARE05541.1\|612820_613111_-	Transposase	NA	NA	NA	NA
ARE05542.1\|613358_613814_+	Transcriptional repressor	NA	NA	NA	NA
ARE05543.1\|613803_616254_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	2.2e-123	34.0
ARE05544.1\|616388_616946_+	sigma 54 modulation protein	NA	NA	NA	NA
ARE05545.1\|617133_618435_+	enolase	A0A1X9I5Z8	Streptococcus_phage	4.0e-217	87.6
ARE05546.1\|618538_619210_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.2e-29	36.8
ARE05547.1\|619211_620285_-	ABC transporter permease	NA	NA	NA	NA
ARE05548.1\|620296_620866_-	transcriptional regulator	NA	NA	NA	NA
ARE05549.1\|621052_622576_-	long-chain acyl-CoA synthetase	NA	NA	NA	NA
ARE05550.1\|622769_623687_+	Mg2 and Co2 transporter CorA family	NA	NA	NA	NA
ARE05551.1\|623946_626310_+	formate acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	3.6e-107	31.8
ARE05552.1\|626438_627098_+	dephospho-CoA kinase	NA	NA	NA	NA
ARE05553.1\|627190_628318_+	multidrug resistance efflux pump	NA	NA	NA	NA
ARE05554.1\|628314_628461_+	LSU ribosomal protein L33P	NA	NA	NA	NA
ARE05555.1\|628838_630101_+	cell division-specific peptidoglycan biosynthesis regulator FtsW	NA	NA	NA	NA
ARE05556.1\|630205_633619_+	pyruvate carboxylase	NA	NA	NA	NA
ARE05557.1\|635084_637631_+	aconitate hydratase	NA	NA	NA	NA
ARE05558.1\|637650_638889_+	Isocitrate dehydrogenase [NADP]	NA	NA	NA	NA
ARE05559.1\|638928_639528_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	7.1e-52	52.6
ARE05560.1\|639722_640253_+	hypothetical protein	NA	NA	NA	NA
ARE05561.1\|640422_640821_+	Arsenate reductase related protein glutaredoxin family	NA	NA	NA	NA
ARE05562.1\|640971_641106_-	secreted protein	NA	NA	NA	NA
ARE05563.1\|641202_642366_-	ABC transporter, permease protein	NA	NA	NA	NA
ARE05564.1\|645431_645665_+\|transposase	IS981 transposase A	A0A1P8CWP5	Bacillus_phage	2.1e-07	35.1
ARE05565.1\|645702_646542_+	Transposase	A0A1P8CWQ3	Bacillus_phage	9.3e-50	41.4
ARE05566.1\|646643_646901_+	hypothetical protein	NA	NA	NA	NA
ARE05567.1\|647007_647898_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_7

840443 : 953721

108

Bacillus_phage(23.08%)

integrase,transposase

attL 892820:892837|attR 942799:942816

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05738.1\|840443_841334_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05739.1\|841920_842181_+	Transposase	A0A1P8CWP5	Bacillus_phage	6.5e-10	40.0
ARE05740.1\|842431_843022_+\|transposase	transposase for insertion sequence element IS981O	Q6J1X2	Lactobacillus_phage	1.2e-35	42.6
ARE05741.1\|843073_843889_-	glycosyltransferase	NA	NA	NA	NA
ARE05742.1\|844203_845622_+	dipeptidase PepV	NA	NA	NA	NA
ARE05743.1\|845750_846110_+	Phosphopantetheinyl transferase (holo-ACP synthase)	NA	NA	NA	NA
ARE05744.1\|846153_847257_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	6.3e-30	28.1
ARE05745.1\|847417_847846_+	Arsenate reductase related protein glutaredoxin family	NA	NA	NA	NA
ARE05746.1\|847984_849292_+	glutathione reductase	NA	NA	NA	NA
ARE05747.1\|849420_850338_+	ABC-type proline/glycine betaine transport system ATPase component	G3M9Y6	Bacillus_virus	9.0e-22	30.1
ARE05748.1\|850334_851837_+	Glycine betaine ABC transporter permease and substrate-binding protein	NA	NA	NA	NA
ARE05749.1\|852098_854633_+	putative extracellular protein	NA	NA	NA	NA
ARE05750.1\|854619_855147_+	hypothetical protein	NA	NA	NA	NA
ARE05751.1\|855156_855534_+	hypothetical protein	NA	NA	NA	NA
ARE05752.1\|855549_856128_+	hypothetical protein	NA	NA	NA	NA
ARE05753.1\|856109_857000_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05754.1\|857188_859231_-	Cation transport ATPase	A0A218MNH6	uncultured_virus	5.8e-61	30.9
ARE05755.1\|859389_860277_+	5,10-methylenetetrahydrofolate dehydrogenase (NADP+)	A0A249XZQ2	Enterococcus_phage	2.1e-39	39.0
ARE05756.1\|860447_861701_+	Exodeoxyribonuclease VII large subunit	A0A2H4UVM9	Bodo_saltans_virus	1.2e-45	32.3
ARE05757.1\|861703_861943_+	Exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
ARE05758.1\|862169_863060_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05759.1\|863118_864264_+	Glycerate kinase	W6LM47	Streptococcus_phage	4.5e-47	38.8
ARE05760.1\|864488_865346_+	Dimethylallyltransferase/geranyltranstransferase	NA	NA	NA	NA
ARE05761.1\|865346_865847_+	acetyltransferase	NA	NA	NA	NA
ARE05762.1\|865922_866729_+	rRNA methylase	NA	NA	NA	NA
ARE05763.1\|866725_867172_+	transcriptional regulator ArgR family	NA	NA	NA	NA
ARE05764.1\|867351_869019_+	DNA repair protein recN	NA	NA	NA	NA
ARE05765.1\|869718_870285_+	hypothetical protein	NA	NA	NA	NA
ARE05766.1\|870379_870901_+	hypothetical protein	NA	NA	NA	NA
ARE05767.1\|872079_873033_+	S-adenosyl-methyltransferase MraW	NA	NA	NA	NA
ARE05768.1\|873188_873569_+	Cell division protein FtsL DivIC superfamily	NA	NA	NA	NA
ARE05769.1\|873565_875863_+	Cell division specific DD-transpeptidase FtsI	NA	NA	NA	NA
ARE05770.1\|875937_876927_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
ARE05771.1\|877125_877410_+	hypothetical protein	NA	NA	NA	NA
ARE05772.1\|879185_879848_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-21	32.7
ARE05773.1\|880207_881095_+	malolactic fermentation system transcription activator	NA	NA	NA	NA
ARE05774.1\|881353_882244_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05775.1\|882330_883005_+	RelA / SpoT (ppGpp synthetase/hydrolase) catalytic domain	NA	NA	NA	NA
ARE05776.1\|883164_883509_+	LSU ribosomal protein L19P	NA	NA	NA	NA
ARE05777.1\|883684_884014_-	hypothetical protein	NA	NA	NA	NA
ARE05778.1\|884438_884900_-	Acetyltransferase GNAT family	NA	NA	NA	NA
ARE05779.1\|885154_885454_+	hypothetical protein	NA	NA	NA	NA
ARE05780.1\|885657_886986_+	Glycosyltransferase family 2 cellulose synthase (CESA) superfamily	NA	NA	NA	NA
ARE05781.1\|887216_887774_+	hypothetical protein	NA	NA	NA	NA
ARE05782.1\|887836_888082_-	hypothetical protein	NA	NA	NA	NA
ARE05783.1\|888354_889080_+	Nicotinamide mononucleotide transporter	A0A2P0ZKW0	Lactobacillus_phage	1.1e-14	28.7
ARE05784.1\|889222_889378_-	hypothetical protein	NA	NA	NA	NA
ARE05785.1\|889632_890058_+	universal stress protein A	NA	NA	NA	NA
ARE05786.1\|890225_890588_+	HU-like DNA-binding protein	NA	NA	NA	NA
ARE05787.1\|890649_891183_-	transcriptional regulator TetR family	NA	NA	NA	NA
ARE05788.1\|891854_892745_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
892820:892837	attL	NA	NA	NA	NA
ARE05789.1\|894939_895272_+	metal-sulfur cluster biosynthetic enzyme	NA	NA	NA	NA
ARE05790.1\|895407_896382_+\|integrase	integrase/recombinase	A0A142F1N9	Bacillus_phage	1.9e-30	28.3
ARE05791.1\|896569_897190_-	hypothetical protein	NA	NA	NA	NA
ARE05792.1\|897266_897527_+	Transposase	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE05793.1\|897538_898378_+\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	6.0e-49	41.4
ARE05794.1\|898725_899022_+	hypothetical protein	NA	NA	NA	NA
ARE05795.1\|899356_899986_+	membrane protein	NA	NA	NA	NA
ARE05796.1\|899982_900981_+	Two-component sensor protein kinase	NA	NA	NA	NA
ARE05797.1\|901008_901638_+	DNA-binding response regulator (Rec-wHTH domains)	NA	NA	NA	NA
ARE05798.1\|901708_902515_+	Hydrolase HAD superfamily Cof subfamily	NA	NA	NA	NA
ARE05799.1\|902614_903205_+	peptidyl-prolyl cis-trans isomerase	A0A1V0S9I2	Catovirus	3.2e-28	45.5
ARE05800.1\|903206_903638_+	RNA binding protein (contains ribosomal protein S1 domain)	NA	NA	NA	NA
ARE05801.1\|903634_904240_+	hypothetical protein	M1Q152	Streptococcus_phage	1.0e-29	36.9
ARE05802.1\|904451_905696_+	rod shape-determining protein RodA	NA	NA	NA	NA
ARE05803.1\|907027_907789_+	Acetoin dehydrogenase	NA	NA	NA	NA
ARE05804.1\|908061_908223_+	hypothetical protein	NA	NA	NA	NA
ARE05805.1\|908333_909884_+	ABC transporter ATP-binding protein	Q6DMX7	Streptococcus_phage	2.0e-26	23.8
ARE05806.1\|910298_911921_+	NAD-dependent malic enzyme	NA	NA	NA	NA
ARE05807.1\|911935_913213_+	Na+/malate symporter	NA	NA	NA	NA
ARE05808.1\|913397_914297_+	permease of the drug/metabolite transporter (DMT) superfamily	NA	NA	NA	NA
ARE05809.1\|914419_915184_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.5e-27	28.4
ARE05810.1\|915164_916745_+	ABC transporter permease protein	NA	NA	NA	NA
ARE05811.1\|917830_918478_+	P-Ser-HPr phosphatase	NA	NA	NA	NA
ARE05812.1\|918631_920587_+	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	2.9e-142	44.7
ARE05813.1\|920683_920869_+	hypothetical protein	NA	NA	NA	NA
ARE05814.1\|921748_922258_+	SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.6e-47	55.4
ARE05815.1\|922430_923072_+	secreted protein	NA	NA	NA	NA
ARE05816.1\|923229_923694_+	MarR family transcriptional regulator	NA	NA	NA	NA
ARE05817.1\|923752_925231_+	Multidrug resistance protein B MF superfamily	NA	NA	NA	NA
ARE05818.1\|925230_925950_+	hypothetical protein	NA	NA	NA	NA
ARE05819.1\|926263_927118_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05820.1\|927281_928094_+	Exopolysaccharide biosynthesis protein	NA	NA	NA	NA
ARE05821.1\|928126_928966_-	Transposase	A0A1P8CWQ3	Bacillus_phage	5.5e-50	41.8
ARE05822.1\|928977_929238_-\|transposase	IS981 transposase A	A0A1P8CWP5	Bacillus_phage	6.5e-10	40.0
ARE05823.1\|929340_932352_+	putative glycosyltransferase	NA	NA	NA	NA
ARE05824.1\|932452_933343_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05825.1\|933581_934697_+	CDP-glycerol/poly(glycerophosphate) glycerophosphotransferase	NA	NA	NA	NA
ARE05826.1\|934796_935627_+	Transcriptional regulator	NA	NA	NA	NA
ARE05827.1\|935813_937049_+	Phosphopentomutase	NA	NA	NA	NA
ARE05828.1\|937139_937376_+	hypothetical protein	NA	NA	NA	NA
ARE05829.1\|937446_938151_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
ARE05830.1\|938586_938874_-	hypothetical protein	A0A1B1IMF9	Lactococcus_phage	2.5e-07	87.9
ARE05831.1\|939406_939853_+	hypothetical protein	NA	NA	NA	NA
ARE05832.1\|939936_940263_+	hypothetical protein	NA	NA	NA	NA
ARE05833.1\|940423_942091_+	Formate-tetrahydrofolate ligase	NA	NA	NA	NA
ARE05834.1\|942199_942793_+	Cell wall-associated hydrolase	A0A1V0DZX6	Clostridioides_phage	2.4e-15	43.5
ARE05835.1\|942818_943307_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
942799:942816	attR	NA	NA	NA	NA
ARE05836.1\|943260_943710_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE05837.1\|943945_944794_+	amino acid ABC transporter substrate binding protein	NA	NA	NA	NA
ARE05838.1\|945177_945948_+	amino-acid ABC transporter permease protein	NA	NA	NA	NA
ARE05839.1\|945959_946712_+	Thioredoxin-disulfide reductase	G9BWD6	Planktothrix_phage	1.8e-28	39.2
ARE05840.1\|947138_948065_+	Thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-85	51.1
ARE05841.1\|948205_948454_+	Preprotein translocase subunit SecG	NA	NA	NA	NA
ARE05842.1\|948695_951149_+	Exoribonuclease R VacB family	Q0GXV6	Lactococcus_phage	1.3e-104	44.2
ARE05843.1\|951167_951755_+	Isochorismatase family protein	NA	NA	NA	NA
ARE05844.1\|951832_952849_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
ARE05845.1\|952830_953721_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_8

994480 : 1018178

Bacillus_phage(18.75%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE05886.1\|994480_995173_+	cell division ATP-binding protein	G9BWD6	Planktothrix_phage	4.2e-32	35.3
ARE05887.1\|995165_996101_+	cell division protein ftsX-like protein	NA	NA	NA	NA
ARE05888.1\|996210_997188_-	ribonucleoside-diphosphate reductase class Ib beta subunit	A0A096XT60	Enterococcus_phage	6.0e-117	65.7
ARE05889.1\|997571_999740_-	ribonucleoside-diphosphate reductase class Ib alpha subunit	A8E2R1	Enterococcus_phage	3.3e-256	60.7
ARE05890.1\|999876_1000299_-	ribonucleotide reductase stimulatory protein	A0A142F1R4	Bacillus_phage	1.7e-12	36.4
ARE05891.1\|1000300_1000519_-	ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit	C3U2K9	Lactococcus_phage	5.8e-12	47.6
ARE05892.1\|1000692_1001334_-	acyl-phosphate glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
ARE05893.1\|1001612_1003547_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.4e-125	43.2
ARE05894.1\|1003653_1004190_+	isochorismatase	NA	NA	NA	NA
ARE05895.1\|1004182_1005016_+	DNA polymerase III epsilon chain	A0A0K2SUJ2	Clostridium_phage	1.5e-20	38.7
ARE05896.1\|1005012_1005393_+	Acetyltransferase GNAT family	NA	NA	NA	NA
ARE05897.1\|1005613_1008088_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.0e-96	31.9
ARE05898.1\|1008905_1009586_+	Transposase	A0A1X9I6C6	Streptococcus_phage	8.5e-110	84.5
ARE05899.1\|1010326_1011415_+	riboflavin biosynthesis protein RibD	A0A1V0SE20	Indivirus	8.4e-51	37.8
ARE05900.1\|1011414_1012062_+	Riboflavin synthase alpha chain	A0A2H4PQS5	Staphylococcus_phage	5.5e-42	44.7
ARE05901.1\|1012073_1013270_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.4e-109	50.3
ARE05902.1\|1013296_1013761_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.4e-39	55.3
ARE05903.1\|1013942_1014203_+	Transposase	A0A1P8CWP5	Bacillus_phage	1.1e-09	36.5
ARE05904.1\|1014214_1015054_+\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	6.0e-49	41.1
ARE05905.1\|1015086_1015989_-	transcription regulator	NA	NA	NA	NA
ARE05906.1\|1016087_1016468_+	hypothetical protein	NA	NA	NA	NA
ARE05907.1\|1016757_1017210_+	signal peptidase II Aspartic peptidase MEROPS family A08	NA	NA	NA	NA
ARE05908.1\|1017272_1018178_+	ribosomal large subunit pseudouridine synthase D	A0A2H4UV25	Bodo_saltans_virus	3.5e-10	27.8

DBSCAN-SWA_9

1133306 : 1176705

Bacillus_phage(25.0%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06015.1\|1133306_1134542_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.4e-134	58.6
ARE06016.1\|1134538_1135126_+	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
ARE06017.1\|1135179_1135530_+	Dihydroneopterin aldolase	NA	NA	NA	NA
ARE06018.1\|1135609_1136659_+	GTP cyclohydrolase I	A0A088F7Y4	Vibrio_phage	8.7e-37	45.1
ARE06019.1\|1136655_1137729_+	dihydropteroate synthase	NA	NA	NA	NA
ARE06020.1\|1137731_1138232_+	Dihydroneopterin triphosphate pyrophosphohydrolase	NA	NA	NA	NA
ARE06021.1\|1138247_1139531_+	Folylpolyglutamate synthase / Dihydrofolate synthase	NA	NA	NA	NA
ARE06022.1\|1139659_1140298_+	Deoxynucleoside kinase	Q5ULP7	Lactobacillus_virus	5.4e-50	47.9
ARE06023.1\|1140477_1141764_+	homoserine dehydrogenase	NA	NA	NA	NA
ARE06024.1\|1141768_1142659_+	homoserine kinase	NA	NA	NA	NA
ARE06025.1\|1142912_1143512_+	hypothetical protein	NA	NA	NA	NA
ARE06026.1\|1143554_1144454_+	UDP-N-acetylenolpyruvoylglucosamine reductase	NA	NA	NA	NA
ARE06027.1\|1144913_1146194_+	spermidine/putrescine ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.0e-32	38.4
ARE06028.1\|1146190_1146979_+	spermidine/putrescine ABC transporter permease protein	NA	NA	NA	NA
ARE06029.1\|1146980_1147781_+	spermidine/putrescine ABC transporter permease protein	NA	NA	NA	NA
ARE06030.1\|1147828_1148896_+	spermidine/putrescine ABC transporter substrate-binding protein	NA	NA	NA	NA
ARE06031.1\|1149493_1150105_-	transcriptional regulator AraC family	NA	NA	NA	NA
ARE06032.1\|1150104_1151298_-	hypothetical protein	NA	NA	NA	NA
ARE06033.1\|1151594_1152776_+	hypothetical protein	NA	NA	NA	NA
ARE06034.1\|1152808_1154470_+	Beta-14-xylosidase	NA	NA	NA	NA
ARE06035.1\|1155071_1155305_+	hypothetical protein	NA	NA	NA	NA
ARE06036.1\|1155411_1155756_+	Transcriptional regulator Xre family	NA	NA	NA	NA
ARE06037.1\|1155984_1156743_+	surface protein	NA	NA	NA	NA
ARE06038.1\|1156832_1157723_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06039.1\|1157935_1158250_+	transcriptional regulator	NA	NA	NA	NA
ARE06040.1\|1159007_1159424_+	Arsenate reductase family protein	NA	NA	NA	NA
ARE06041.1\|1159788_1160199_-	transcriptional regulator	NA	NA	NA	NA
ARE06042.1\|1160370_1161228_+	Aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	2.4e-29	30.4
ARE06043.1\|1161265_1162156_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06044.1\|1162573_1163413_-\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	1.8e-48	41.1
ARE06045.1\|1163424_1163685_-\|transposase	IS981 transposase A	A0A1P8CWP5	Bacillus_phage	2.5e-09	36.5
ARE06046.1\|1164028_1164733_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
ARE06047.1\|1165754_1167125_+\|tRNA	tRNA (uracil-5-)-methyltransferase related enzyme	E4ZFI6	Streptococcus_phage	3.8e-141	56.0
ARE06048.1\|1167169_1168777_+	NAD(FAD)-utilizing dehydrogenase	NA	NA	NA	NA
ARE06049.1\|1168778_1169399_+	SAM-dependent methyltransferase	NA	NA	NA	NA
ARE06050.1\|1169464_1170637_+	hypothetical protein	NA	NA	NA	NA
ARE06051.1\|1170664_1171921_+	TPR repeat-containing protein Tetratricopeptide repeat family	NA	NA	NA	NA
ARE06052.1\|1172075_1173740_+	acetolactate synthase	NA	NA	NA	NA
ARE06053.1\|1173846_1174992_-	arabinose efflux permease	NA	NA	NA	NA
ARE06054.1\|1175099_1175498_+	transcriptional regulator	NA	NA	NA	NA
ARE06055.1\|1175814_1176705_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_10

1216415 : 1284233

Bacillus_phage(29.41%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06093.1\|1216415_1217762_+\|tRNA	tRNA (uracil-5-)-methyltransferase Gid	NA	NA	NA	NA
ARE06094.1\|1217811_1218882_-	Site-specific tyrosine recombinase XerC	NA	NA	NA	NA
ARE06095.1\|1219528_1220230_-	hypothetical protein	NA	NA	NA	NA
ARE06096.1\|1220607_1221387_-	NhaP-type Na+/H+ and K+/H+ antiporter	NA	NA	NA	NA
ARE06097.1\|1221487_1222555_-	hypothetical protein	A0A172Q0Y5	Acinetobacter_phage	2.7e-54	40.9
ARE06098.1\|1224028_1224868_+\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	1.8e-48	41.1
ARE06099.1\|1224900_1225221_-	hypothetical protein	NA	NA	NA	NA
ARE06100.1\|1225887_1226745_-	Methylenetetrahydrofolate reductase	NA	NA	NA	NA
ARE06101.1\|1226734_1229008_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
ARE06102.1\|1229167_1229821_-	Iron-dependent repressor	NA	NA	NA	NA
ARE06103.1\|1229913_1232646_-	Mg(2+) transport ATPase P-type	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.9e-43	23.3
ARE06104.1\|1233120_1234407_-	D-alanine transfer protein DltD	NA	NA	NA	NA
ARE06105.1\|1234396_1234636_-	D-alanyl carrier protein	NA	NA	NA	NA
ARE06106.1\|1234671_1235895_-	D-alanyl transfer protein	A0A125RNP0	Pseudomonas_phage	2.4e-22	30.8
ARE06107.1\|1235894_1237394_-	D-alanine--poly(phosphoribitol) ligase subunit 1	A0A2K9L3I8	Tupanvirus	1.8e-40	30.0
ARE06108.1\|1237732_1238389_-	thiamine-phosphate pyrophosphorylase	NA	NA	NA	NA
ARE06109.1\|1238381_1239182_-	Phosphomethylpyrimidine kinase / Hydroxymethylpyrimidine kinase	NA	NA	NA	NA
ARE06110.1\|1239194_1239947_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
ARE06111.1\|1241286_1242177_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06112.1\|1242233_1242974_-	UDP-N-acetylglucosamine 2-epimerase	A0A1V0SAG5	Catovirus	4.0e-20	29.5
ARE06113.1\|1243484_1244321_-	hypothetical protein	NA	NA	NA	NA
ARE06114.1\|1244317_1245877_-	permease of the major facilitator superfamily	NA	NA	NA	NA
ARE06115.1\|1246015_1246249_+\|transposase	IS981 transposase A	A0A1P8CWP5	Bacillus_phage	2.1e-07	35.1
ARE06116.1\|1246286_1247126_+	Transposase	A0A1P8CWQ3	Bacillus_phage	9.3e-50	41.4
ARE06117.1\|1247177_1247513_-	MarR family transcriptional regulator	NA	NA	NA	NA
ARE06118.1\|1247936_1248302_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
ARE06119.1\|1248371_1248887_-	LSU ribosomal protein L10P	NA	NA	NA	NA
ARE06120.1\|1249140_1249566_-	hypothetical protein	NA	NA	NA	NA
ARE06121.1\|1249813_1250002_-	hypothetical protein	NA	NA	NA	NA
ARE06122.1\|1250015_1250774_-	transcriptional regulator	R9TNM0	Vibrio_phage	3.7e-05	26.6
ARE06123.1\|1250892_1252677_-	Multidrug/protein/lipid ABC transporter family ATP-binding and permease protein	W8CYL7	Bacillus_phage	2.5e-44	28.0
ARE06124.1\|1252660_1254478_-	Multidrug resistance ABC transporter ATP-binding and permease protein	W8CYL7	Bacillus_phage	1.1e-44	27.4
ARE06125.1\|1254615_1255866_-	Glycoside hydrolase family 25	A0A2H4PQN5	Staphylococcus_phage	2.1e-05	26.3
ARE06126.1\|1255879_1256470_-	Glycoside hydrolase family 25	NA	NA	NA	NA
ARE06127.1\|1256523_1257111_-	Glycoside hydrolase family 25	NA	NA	NA	NA
ARE06128.1\|1257421_1258042_-	Riboflavin transporter	NA	NA	NA	NA
ARE06129.1\|1258390_1259152_-	ribosomal large subunit pseudouridine synthase B	NA	NA	NA	NA
ARE06130.1\|1259096_1259663_-	condensin subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.5e-14	34.4
ARE06131.1\|1259655_1260384_-	segregation and condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.5e-08	35.5
ARE06132.1\|1260414_1261161_-	tyrosine recombinase XerD subunit	NA	NA	NA	NA
ARE06133.1\|1261108_1261570_-	CBS domain containing protein	NA	NA	NA	NA
ARE06134.1\|1261600_1262104_-	Phosphoesterase family protein	NA	NA	NA	NA
ARE06135.1\|1262142_1262748_-	Purine NTP pyrophosphatase rdgB/HAM1 family	NA	NA	NA	NA
ARE06136.1\|1262748_1263564_-	glutamate racemase	NA	NA	NA	NA
ARE06137.1\|1263739_1263979_-	hypothetical protein	NA	NA	NA	NA
ARE06138.1\|1264129_1265389_-	Diaminopimelate decarboxylase	NA	NA	NA	NA
ARE06139.1\|1265503_1266943_-	Glutamate synthase [NADPH] small chain	NA	NA	NA	NA
ARE06140.1\|1266942_1271412_-	Glutamate synthase [NADPH] large chain	NA	NA	NA	NA
ARE06141.1\|1271580_1272192_+	O-acetyltransferase	NA	NA	NA	NA
ARE06142.1\|1272224_1273247_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
ARE06143.1\|1273406_1274162_+	Small-conductance mechanosensitive channel	NA	NA	NA	NA
ARE06144.1\|1275647_1277159_-	glutamate/gamma-aminobutyrate antiporter	NA	NA	NA	NA
ARE06145.1\|1277201_1278092_-	transcriptional regulator	NA	NA	NA	NA
ARE06146.1\|1278570_1279461_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06147.1\|1279694_1280480_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	2.0e-25	41.9
ARE06148.1\|1280583_1281432_-	ribosomal biogenesis GTPase	NA	NA	NA	NA
ARE06149.1\|1281661_1282174_-	Acetyltransferase (GNAT) family	NA	NA	NA	NA
ARE06150.1\|1282249_1282978_-\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	6.0e-130	99.2
ARE06151.1\|1282922_1284233_-\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	3.1e-225	99.7

DBSCAN-SWA_11

1309037 : 1374204

Bacillus_phage(44.44%)

lysis,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06172.1\|1309037_1309928_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06173.1\|1310147_1310333_-	hypothetical protein	NA	NA	NA	NA
ARE06174.1\|1310332_1312945_-	extracellular LPXTG-anchored protein	R9R2F6	Lactococcus_phage	3.4e-05	45.7
ARE06175.1\|1313287_1313731_-	hypothetical protein	NA	NA	NA	NA
ARE06176.1\|1314035_1315658_+	Fibronectin-binding protein	Q84500	Paramecium_bursaria_Chlorella_virus	5.5e-06	32.1
ARE06177.1\|1315699_1316515_+	23S rRNA m(1)G 745 methyltransferase	NA	NA	NA	NA
ARE06178.1\|1316696_1318217_+	purine/cytidine ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.4e-19	32.1
ARE06179.1\|1318209_1319304_+	purine/cytidine ABC transporter permease protein	NA	NA	NA	NA
ARE06180.1\|1319300_1320254_+	nucleoside ABC transporter membrane protein	NA	NA	NA	NA
ARE06181.1\|1320370_1321348_-	L-lactate dehydrogenase	NA	NA	NA	NA
ARE06182.1\|1321465_1322974_-	pyruvate kinase	NA	NA	NA	NA
ARE06183.1\|1323061_1324084_-	6-phosphofructokinase	NA	NA	NA	NA
ARE06184.1\|1324471_1325620_-	N-acetylglucosamine 6-phosphate deacetylase	NA	NA	NA	NA
ARE06185.1\|1325790_1326969_-	toxic anion resistance protein	A0A291I9K4	Lactobacillus_phage	1.5e-37	28.8
ARE06186.1\|1327110_1327737_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis protein	NA	NA	NA	NA
ARE06187.1\|1327927_1328956_+	Glycerol-3-phosphate dehydrogenase [NAD(P) ]	NA	NA	NA	NA
ARE06188.1\|1328997_1329939_+	UDP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	4.8e-79	51.9
ARE06189.1\|1330009_1330417_+	hypothetical protein	NA	NA	NA	NA
ARE06190.1\|1330413_1330944_+	heptaprenyl diphosphate synthase component I	NA	NA	NA	NA
ARE06191.1\|1330934_1331894_+	heptaprenyl diphosphate synthase component II	NA	NA	NA	NA
ARE06192.1\|1331890_1332607_+	16S rRNA methyltransferase GidB	NA	NA	NA	NA
ARE06193.1\|1332615_1333074_-	hypothetical protein	NA	NA	NA	NA
ARE06194.1\|1333075_1333789_-	orotidine-5-phosphate decarboxylase	NA	NA	NA	NA
ARE06195.1\|1333918_1334854_-	dihydroorotate dehydrogenase 1B	NA	NA	NA	NA
ARE06196.1\|1335084_1335873_-	Dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
ARE06197.1\|1336122_1337487_-	Multidrug resistance protein B MF superfamily	NA	NA	NA	NA
ARE06198.1\|1337684_1338401_-	transcriptional regulator GntR family	NA	NA	NA	NA
ARE06199.1\|1338471_1339899_-	Beta-glucosidase/6-phospho-beta- glucosidase/beta-galactosidase	NA	NA	NA	NA
ARE06200.1\|1339908_1340649_-	3-ketoacyl-(acyl-carrier-protein) reductase	NA	NA	NA	NA
ARE06201.1\|1340649_1341195_-	hypothetical protein	NA	NA	NA	NA
ARE06202.1\|1341191_1342028_-	sugar transport system permease protein	NA	NA	NA	NA
ARE06203.1\|1342027_1342984_-	carbohydrate ABC transporter membrane protein 1 CUT1 family	NA	NA	NA	NA
ARE06204.1\|1343018_1344338_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
ARE06205.1\|1345480_1346419_+	acetylxylan esterase	NA	NA	NA	NA
ARE06206.1\|1346567_1347797_+	hypothetical protein	NA	NA	NA	NA
ARE06207.1\|1348010_1349162_+	ATP/GTP binding protein	NA	NA	NA	NA
ARE06208.1\|1349158_1349944_+	Beta-propeller domains of methanol dehydrogenase type	NA	NA	NA	NA
ARE06209.1\|1349978_1350512_-	ribosomal large subunit pseudouridine synthase E	NA	NA	NA	NA
ARE06210.1\|1350811_1352329_+	glycerol kinase	NA	NA	NA	NA
ARE06211.1\|1352381_1353959_+	Alpha-glycerophosphate oxidase	NA	NA	NA	NA
ARE06212.1\|1353977_1354571_+	glycerol uptake facilitator	NA	NA	NA	NA
ARE06213.1\|1354490_1354760_-	cell surface protein	NA	NA	NA	NA
ARE06214.1\|1354838_1355651_-	hypothetical protein	NA	NA	NA	NA
ARE06215.1\|1355631_1355967_-	hypothetical protein	NA	NA	NA	NA
ARE06216.1\|1356282_1357122_-\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	1.2e-49	41.4
ARE06217.1\|1357133_1357394_-\|transposase	IS981 transposase A	A0A1P8CWP5	Bacillus_phage	1.9e-09	37.6
ARE06218.1\|1357414_1358074_-	hypothetical protein	NA	NA	NA	NA
ARE06219.1\|1358241_1360152_-	hypothetical protein	NA	NA	NA	NA
ARE06220.1\|1360227_1360809_-	hypothetical protein	NA	NA	NA	NA
ARE06221.1\|1361007_1364202_-	Carbamoyl-phosphate synthase large chain	NA	NA	NA	NA
ARE06222.1\|1364551_1365025_-	Glutathione peroxidase	NA	NA	NA	NA
ARE06223.1\|1365923_1368557_-	Calcium-transporting ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	4.5e-90	30.8
ARE06224.1\|1368814_1369540_-	hypothetical protein	NA	NA	NA	NA
ARE06225.1\|1369759_1370191_-	hypothetical protein	NA	NA	NA	NA
ARE06226.1\|1370247_1371087_-	Transposase	A0A1P8CWQ3	Bacillus_phage	5.5e-50	41.8
ARE06227.1\|1371098_1371251_-	Transposase	NA	NA	NA	NA
ARE06228.1\|1371507_1371954_+	hypothetical protein	NA	NA	NA	NA
ARE06229.1\|1372224_1373115_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06230.1\|1373313_1374204_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

DBSCAN-SWA_12

1391708 : 1453251

Acinetobacter_phage(17.65%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06251.1\|1391708_1392932_-\|holin	Glycine betaine/carnitine/choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-28	36.9
ARE06252.1\|1393143_1393764_-	transcriptional regulator GntR family	NA	NA	NA	NA
ARE06253.1\|1393929_1394661_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
ARE06254.1\|1394803_1395484_-	Transposase	A0A1X9I6C6	Streptococcus_phage	3.2e-109	84.1
ARE06255.1\|1395520_1396045_-	transcriptional antiterminator BglG family	NA	NA	NA	NA
ARE06256.1\|1396220_1396982_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
ARE06257.1\|1396981_1398187_-	Tryptophan synthase beta chain	NA	NA	NA	NA
ARE06258.1\|1398285_1398804_-	Acetyltransferase including N-acetylase of ribosomal protein	NA	NA	NA	NA
ARE06259.1\|1398793_1399852_-	N-(5-phosphoribosyl)anthranilate isomerase	NA	NA	NA	NA
ARE06260.1\|1399841_1400636_-	indole-3-glycerol phosphate synthase	A0A0P0IR83	Acinetobacter_phage	1.7e-29	35.5
ARE06261.1\|1401299_1401653_-	hypothetical protein	NA	NA	NA	NA
ARE06262.1\|1401607_1402102_-	hypothetical protein	NA	NA	NA	NA
ARE06263.1\|1402299_1403307_-	Anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	6.6e-50	35.9
ARE06264.1\|1403311_1403893_-	anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.5e-33	45.1
ARE06265.1\|1403944_1405315_-	anthranilate synthase component I	NA	NA	NA	NA
ARE06266.1\|1405768_1406128_-	membrane protein	NA	NA	NA	NA
ARE06267.1\|1406142_1406781_-	Nitroreductase/Transcriptional regulator MarR family	NA	NA	NA	NA
ARE06268.1\|1406792_1407212_-	Nitroreductase/Transcriptional regulator, MarR family	NA	NA	NA	NA
ARE06269.1\|1407321_1408065_-	Methylase for ubiquinone/menaquinone biosynthesis	NA	NA	NA	NA
ARE06270.1\|1408140_1408821_-	hypothetical protein	NA	NA	NA	NA
ARE06271.1\|1408820_1409510_-	hypothetical protein	NA	NA	NA	NA
ARE06272.1\|1409636_1410023_+	ferric uptake regulation protein	NA	NA	NA	NA
ARE06273.1\|1410203_1411094_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06274.1\|1411190_1411544_-	transcriptional regulator	NA	NA	NA	NA
ARE06275.1\|1411701_1412433_+	Short-chain alcohol dehydrogenase	A0A2P0VP75	Tetraselmis_virus	5.5e-06	28.8
ARE06276.1\|1412542_1414342_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
ARE06277.1\|1414602_1415022_-	transcriptional regulator MarR family	NA	NA	NA	NA
ARE06278.1\|1415197_1416103_+	cationic transporter	NA	NA	NA	NA
ARE06279.1\|1416201_1417581_+	Na+-driven multidrug efflux pump MatE family	NA	NA	NA	NA
ARE06280.1\|1417624_1420039_-	hypothetical protein	NA	NA	NA	NA
ARE06281.1\|1420061_1420760_-	secreted protein	NA	NA	NA	NA
ARE06282.1\|1420879_1422514_-	Oligosaccharide ABC transporter oligosaccharide-binding protein	NA	NA	NA	NA
ARE06283.1\|1422585_1423449_-	Oligosaccharider ABC transporter permease protein	NA	NA	NA	NA
ARE06284.1\|1423459_1424350_-	Oligosaccharide ABC transporter permease protein	NA	NA	NA	NA
ARE06285.1\|1424682_1426224_-	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	7.0e-19	30.3
ARE06286.1\|1426433_1427309_-	fructokinase	NA	NA	NA	NA
ARE06287.1\|1427439_1428330_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06288.1\|1429344_1430670_-	Xylose isomerase	NA	NA	NA	NA
ARE06289.1\|1430780_1431713_+	xylose operon regulator	NA	NA	NA	NA
ARE06290.1\|1431868_1432975_-	phosphoribosylaminoimidazole carboxylase ATPase subunit	NA	NA	NA	NA
ARE06291.1\|1433030_1433516_-	phosphoribosylaminoimidazole carboxylase catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	7.3e-23	43.0
ARE06292.1\|1433512_1434241_-	hydrolase	NA	NA	NA	NA
ARE06293.1\|1434312_1435554_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
ARE06294.1\|1435947_1436574_+	TetR family transcriptional regulator	NA	NA	NA	NA
ARE06295.1\|1438929_1440486_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.6e-71	46.2
ARE06296.1\|1440662_1441205_-	Hypoxanthine-guanine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	6.1e-10	30.6
ARE06297.1\|1442400_1442931_+	Transcriptional regulator TetR family	NA	NA	NA	NA
ARE06298.1\|1442982_1443537_-	ABC-type multidrug transport system ATPase and permease component	F2Y1V6	Organic_Lake_phycodnavirus	1.5e-11	34.3
ARE06299.1\|1443499_1444573_-	Multidrug resistance ABC transporter ATP-binding and permease protein	NA	NA	NA	NA
ARE06300.1\|1444763_1445312_-	formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-19	32.0
ARE06301.1\|1445340_1446357_-	Phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.4e-60	41.5
ARE06302.1\|1446546_1449150_-\|protease	ATP-dependent Clp protease chaperonin ATPase ClpB	K4FB40	Cronobacter_phage	1.4e-123	32.7
ARE06303.1\|1449337_1450096_-	secreted protein	A0A1P8BMN5	Lactococcus_phage	2.0e-11	47.6
ARE06304.1\|1451257_1452481_+\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	6.4e-233	99.8
ARE06305.1\|1452492_1453251_+\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	5.3e-137	100.0

DBSCAN-SWA_13

1524082 : 1564755

Lactococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06381.1\|1524082_1524973_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06382.1\|1525019_1526465_-	Cation binding protein hemerythrin HHE domain family	NA	NA	NA	NA
ARE06383.1\|1526461_1526704_-	hypothetical protein	NA	NA	NA	NA
ARE06384.1\|1526819_1527146_-	Branched-chain amino acid transport protein AzlD	NA	NA	NA	NA
ARE06385.1\|1527132_1527840_-	branched chain amino acid ABC transporter	NA	NA	NA	NA
ARE06386.1\|1528034_1528607_+	NADP oxidoreductase coenzyme F420-dependent	NA	NA	NA	NA
ARE06387.1\|1528676_1529219_+	spermidine acetyltransferase	NA	NA	NA	NA
ARE06388.1\|1529243_1530800_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06389.1\|1531044_1531935_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06390.1\|1531939_1533910_-	extracellular C-terminal membrane anchor protein	NA	NA	NA	NA
ARE06391.1\|1533958_1535671_-	mRNA degradation ribonuclease metallo-beta-lactamase superfamily	NA	NA	NA	NA
ARE06392.1\|1536020_1536692_+	Cation transport ATPase MgtC/SapB family	G3MA03	Bacillus_virus	2.8e-20	44.3
ARE06393.1\|1536731_1537625_-	dihydrodipicolinate synthase	NA	NA	NA	NA
ARE06394.1\|1537953_1538409_-	ADP-ribose pyrophosphatase	D0R7J3	Paenibacillus_phage	1.0e-26	38.9
ARE06395.1\|1538418_1539495_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
ARE06396.1\|1539590_1540454_-	Aquaporin/glycerol uptake facilitator protein MIP family	NA	NA	NA	NA
ARE06397.1\|1540802_1541054_-	hypothetical protein	NA	NA	NA	NA
ARE06398.1\|1541221_1543198_-	transketolase	NA	NA	NA	NA
ARE06399.1\|1543365_1544766_-	PTS system ascorbate-specific transporter subunit IIC	NA	NA	NA	NA
ARE06400.1\|1544818_1545118_-	PTS system IIB component L-Asc family	NA	NA	NA	NA
ARE06401.1\|1545119_1545938_-	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	NA	NA	NA	NA
ARE06402.1\|1547234_1547876_-	2-dehydro-3-deoxyphosphogluconate aldolase	NA	NA	NA	NA
ARE06403.1\|1547878_1548556_-	2-dehydro-3-deoxygluconokinase	NA	NA	NA	NA
ARE06404.1\|1548825_1550244_-	Uronate isomerase	NA	NA	NA	NA
ARE06405.1\|1550256_1551138_-	Aldose 1-epimerase family protein C-terminal protein	NA	NA	NA	NA
ARE06406.1\|1551197_1552724_-	Na+/galactoside symporter	NA	NA	NA	NA
ARE06407.1\|1552909_1553974_-	mannonate dehydratase	NA	NA	NA	NA
ARE06408.1\|1556160_1556841_+	transcriptional regulator GntR family	NA	NA	NA	NA
ARE06409.1\|1556905_1558336_-	Multidrug transporter MF superfamily	NA	NA	NA	NA
ARE06410.1\|1558694_1559000_-	hypothetical protein	NA	NA	NA	NA
ARE06411.1\|1559004_1559229_-	hypothetical protein	NA	NA	NA	NA
ARE06412.1\|1559443_1560334_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06413.1\|1560315_1560516_-	hypothetical protein	NA	NA	NA	NA
ARE06414.1\|1561832_1562567_-	DNA-packaging protein	NA	NA	NA	NA
ARE06415.1\|1562771_1564082_+\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	3.1e-225	99.7
ARE06416.1\|1564026_1564755_+\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	7.1e-131	99.6

DBSCAN-SWA_14

1832694 : 1842991

Lactococcus_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06668.1\|1832694_1833633_-	Glycosyl transferase family 2	V9QJB1	Oenococcus_phage	1.0e-81	50.6
ARE06669.1\|1833550_1835080_-	hypothetical protein	NA	NA	NA	NA
ARE06670.1\|1835241_1836081_-\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	3.5e-49	41.1
ARE06671.1\|1836092_1836353_-	Transposase	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE06672.1\|1836464_1836791_-	hypothetical protein	NA	NA	NA	NA
ARE06673.1\|1836862_1837282_-	deoxyuridine 5-triphosphate nucleotidohydrolase	A5GYP0	Lactococcus_phage	9.0e-70	95.7
ARE06674.1\|1837513_1838272_-\|transposase	transposase helper protein for IS712H	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
ARE06675.1\|1838283_1839507_-\|transposase	transposase for insertion sequence element IS712H	A0A059NT83	Lactococcus_phage	6.4e-233	99.8
ARE06676.1\|1839582_1840107_-	hypothetical protein	NA	NA	NA	NA
ARE06677.1\|1840369_1840954_+	cI-like repressor	A5GYQ3	Lactococcus_phage	4.0e-60	72.2
ARE06678.1\|1840959_1841394_+	hypothetical protein	NA	NA	NA	NA
ARE06679.1\|1841407_1841743_+	hypothetical protein	NA	NA	NA	NA
ARE06680.1\|1841809_1842991_+	Integrase	Q9AZK8	Lactococcus_phage	2.0e-90	47.5

DBSCAN-SWA_15

2044439 : 2093590

Bacillus_phage(36.36%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ARE06854.1\|2044439_2045330_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06855.1\|2046582_2047722_-	transcription regulator/NMN adenylyltransferase/ribosylnicotinamide kinase	A0A2K9VDE3	Lactobacillus_phage	1.5e-119	55.4
ARE06856.1\|2047708_2048686_-	D-Isomer specific 2-hydroxyacid dehydrogenase NAD-dependent	NA	NA	NA	NA
ARE06857.1\|2048883_2050176_-	Peptidase U32 family	Q6DW11	Phage_TP	1.0e-39	33.7
ARE06858.1\|2050460_2051432_-	Peptidase U32 family	NA	NA	NA	NA
ARE06859.1\|2051603_2051885_+	hypothetical protein	NA	NA	NA	NA
ARE06860.1\|2051914_2052736_-	23S rRNA m(1)G-748 methyltransferase	NA	NA	NA	NA
ARE06861.1\|2052854_2053481_+	Copper homeostasis protein	NA	NA	NA	NA
ARE06862.1\|2053513_2054533_-	ABC-type transporter ATP-binding protein	NA	NA	NA	NA
ARE06863.1\|2054525_2055296_-	ABC-type multidrug transport system ATPase component	A0A2H4PQG7	Staphylococcus_phage	4.9e-29	32.8
ARE06864.1\|2055314_2056205_-	glycerophosphoryl diester phosphodiesterase	A0A076G4Q2	Staphylococcus_phage	6.5e-09	26.6
ARE06865.1\|2056718_2057558_-\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	4.6e-49	41.4
ARE06866.1\|2057569_2057830_-	Transposase	A0A1P8CWP5	Bacillus_phage	1.1e-09	36.5
ARE06867.1\|2058098_2058497_+	Diadenosine tetraphosphate (Ap4A) hydrolase related HIT family hydrolase	NA	NA	NA	NA
ARE06868.1\|2058511_2058733_+	hypothetical protein	NA	NA	NA	NA
ARE06869.1\|2058744_2059104_-	hypothetical protein	NA	NA	NA	NA
ARE06870.1\|2059166_2059856_-	LSU ribosomal protein L1P	NA	NA	NA	NA
ARE06871.1\|2060242_2060668_-	LSU ribosomal protein L11P	NA	NA	NA	NA
ARE06872.1\|2060803_2061568_-	ABC transporter permease protein	NA	NA	NA	NA
ARE06873.1\|2061567_2062446_-	bacitracin transport ATP-binding protein	A0A2K9L0W2	Tupanvirus	1.9e-05	26.4
ARE06874.1\|2062512_2062722_-	hypothetical protein	NA	NA	NA	NA
ARE06875.1\|2062755_2063277_-	Peptide methionine sulfoxide reductase	NA	NA	NA	NA
ARE06876.1\|2063451_2064309_-	RNA binding domain protein	NA	NA	NA	NA
ARE06877.1\|2064353_2064812_-	Acetyltransferase GNAT family	NA	NA	NA	NA
ARE06878.1\|2064896_2065454_-	ribosome recycling factor	NA	NA	NA	NA
ARE06879.1\|2065609_2066326_-	uridylate kinase	NA	NA	NA	NA
ARE06880.1\|2066410_2066863_-	hypothetical protein	NA	NA	NA	NA
ARE06881.1\|2066992_2068180_-	acetate kinase	NA	NA	NA	NA
ARE06882.1\|2068338_2069526_-	AckA1 protein	NA	NA	NA	NA
ARE06883.1\|2069717_2070656_-	Adenine-specific methyltransferase	NA	NA	NA	NA
ARE06884.1\|2070743_2070995_-	hypothetical protein	NA	NA	NA	NA
ARE06885.1\|2071095_2072937_-	membrane GTPase for stress response	A0A1S5SF82	Streptococcus_phage	1.2e-17	35.4
ARE06886.1\|2073104_2073578_-	hypothetical protein	NA	NA	NA	NA
ARE06887.1\|2073700_2074540_-\|transposase	transposase for insertion sequence element IS981O	A0A1P8CWQ3	Bacillus_phage	4.6e-49	41.4
ARE06888.1\|2074551_2074812_-	Transposase	A0A1P8CWP5	Bacillus_phage	8.4e-10	37.6
ARE06889.1\|2074848_2075058_-	hypothetical protein	NA	NA	NA	NA
ARE06890.1\|2075305_2076196_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06891.1\|2076256_2076715_-	hypothetical protein	NA	NA	NA	NA
ARE06892.1\|2076729_2077344_-	putative extracellular protein	NA	NA	NA	NA
ARE06893.1\|2077683_2078412_-	Two-component system response regulator LytTR family	NA	NA	NA	NA
ARE06894.1\|2078604_2078826_+	hypothetical protein	NA	NA	NA	NA
ARE06895.1\|2078859_2079831_+	glucokinase	NA	NA	NA	NA
ARE06896.1\|2079833_2080220_+	Rhodanese-related sulfurtransferase	NA	NA	NA	NA
ARE06897.1\|2080335_2080782_-	non-heme iron-binding ferritin	A0A0A7RTZ1	Clostridium_phage	1.6e-16	32.6
ARE06898.1\|2080947_2081535_+	ComC competence protein	NA	NA	NA	NA
ARE06899.1\|2081574_2082429_-\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA
ARE06900.1\|2082570_2083665_-	Nucleotidyltransferase/DNA polymerase for DNA repair	NA	NA	NA	NA
ARE06901.1\|2083740_2084232_-\|tRNA	Ala-tRNA(Pro) hydrolase	NA	NA	NA	NA
ARE06902.1\|2084307_2085801_-	arginine/ornithine antiporter	NA	NA	NA	NA
ARE06903.1\|2087384_2088329_-	carbamate kinase	NA	NA	NA	NA
ARE06904.1\|2088346_2089927_-	arginine/ornithine antiporter	NA	NA	NA	NA
ARE06905.1\|2090058_2091123_-	ornithine carbamoyltransferase	NA	NA	NA	NA
ARE06906.1\|2091288_2092521_-	arginine deiminase	NA	NA	NA	NA
ARE06907.1\|2092735_2093590_+\|transposase	transposase for insertion sequence element IS982B	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP016707

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP016708

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. CP015907

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection