CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022059	Enterococcus faecalis strain FDAARGOS_338 chromosome, complete genome	3 crisprs	cas2,cas1,cas9,cas3,csa3,WYL,DEDDh,cas14j,DinG	0	9	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP022059_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022059_1

4162-4791

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR

9 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP022059_1

>merge|CP022059|1|4162-4791|CRISPRCasFinder,CRT,PILER-CR
CGTATCTGCGAAAACTAAACAACATGACTCTAAAACATATGTAAATCATAATGAGCATTTACATTGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCAAGCGATGGAGCAGGTTGGTCTGCTATGAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCCACGCTCCGGCAATTTCCCGACAACTGATGTTTTGGTACCATTCTAAACAACATGACTCTAAAACACCATTGACAACAATATTCTTTTGTTGCACGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCTATAATGCCTGTGAGTAGCGTGTGTGTGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCCCGTCTGTAATACACGTAACAACAAGCCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGATAGTTGCGCTAATATCAATCGTGCTTCGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATGCTTCGACCAGCACCACCAAAGTCTGCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGGATCCATATTCTGATATGTACAGAGGGATGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|1|1|4162-4791|CRISPRCasFinder
CGTATCTGCGAAAACTAAACAACATGACTCTAAAAC	ATATGTAAATCATAATGAGCATTTACATTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAAGCGATGGAGCAGGTTGGTCTGCTATGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCACGCTCCGGCAATTTCCCGACAACTGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACCATTGACAACAATATTCTTTTGTTGCAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAGTTGCGCTAATATCAATCGTGCTTCG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGCTTCGACCAGCACCACCAAAGTCTGCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGATCCATATTCTGATATGTACAGAGGGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|1|1|4162-4791|CRT
CGTATCTGCGAAAACTAAACAACATGACTCTAAAAC	ATATGTAAATCATAATGAGCATTTACATTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAAGCGATGGAGCAGGTTGGTCTGCTATGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCACGCTCCGGCAATTTCCCGACAACTGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACCATTGACAACAATATTCTTTTGTTGCAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAGTTGCGCTAATATCAATCGTGCTTCG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGCTTCGACCAGCACCACCAAAGTCTGCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGATCCATATTCTGATATGTACAGAGGGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|1|1|4228-4791|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAAGCGATGGAGCAGGTTGGTCTGCTATGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCACGCTCCGGCAATTTCCCGACAACTGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ACCATTGACAACAATATTCTTTTGTTGCAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAGTTGCGCTAATATCAATCGTGCTTCG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATGCTTCGACCAGCACCACCAAAGTCTGCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GGATCCATATTCTGATATGTACAGAGGGAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP022059.2\|ASE64430.1\|2766_3780_+\|acyltransferase	unknown	unknown	gnl\|CDD\|226122
CP022059.2\|ASE64429.1\|1577_2531_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
CP022059.2\|ASE64432.1\|5543_5873_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP022059.2\|ASE64433.1\|5869_6736_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP022059.2\|ASE64428.1\|59_1577_-\|glycine/betaine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|270328
CP022059.2\|ASE64431.1\|4883_5543_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP022059.2\|ASE64437.1\|13149_13923_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
CP022059.2\|AVK72504.1\|15845_17372_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	unknown	unknown	gnl\|CDD\|237588
CP022059.2\|ASE64434.1\|6736_10750_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP022059.2\|ASE64438.1\|13992_15642_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
CP022059.2\|ASE64435.1\|11222_11456_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE64439.1\|17438_18011_-\|phospholipase	unknown	unknown	gnl\|CDD\|223477
CP022059.2\|ASE64436.1\|11600_13016_-\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|130941

Protein	Function_ID	Function_description	E-value
CP022059.2\|ASE64430.1\|2766_3780_+\|acyltransferase	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.63008e-11
CP022059.2\|ASE64429.1\|1577_2531_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.78143e-140
CP022059.2\|ASE64432.1\|5543_5873_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.08189e-44
CP022059.2\|ASE64428.1\|59_1577_-\|glycine/betaine-ABC-transporter-permease	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.06182e-168
CP022059.2\|ASE64431.1\|4883_5543_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.31098e-118
CP022059.2\|ASE64437.1\|13149_13923_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	1.20502e-91
CP022059.2\|AVK72504.1\|15845_17372_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	gnl\|CDD\|237588	PRK14022, PRK14022, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.	0
CP022059.2\|ASE64434.1\|6736_10750_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP022059.2\|ASE64438.1\|13992_15642_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.27874e-136
CP022059.2\|ASE64433.1\|5869_6736_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.59266e-115
CP022059.2\|ASE64439.1\|17438_18011_-\|phospholipase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	4.15912e-18
CP022059.2\|ASE64436.1\|11600_13016_-\|dipeptidase-PepV	gnl\|CDD\|130941	TIGR01886, Beta-Ala-Xaa_dipeptidase, dipeptidase PepV. This model represents a small clade of dipeptidase enzymes which are members of the larger M25 subfamily of metalloproteases. Two characterized enzymes are included in the seed. One, from Lactococcus lactis has been shown to act on a wide range of dipeptides, but not larger peptides. The enzyme from Lactobacillus delbrueckii was originally characterized as a Xaa-His dipeptidase, specifically a carnosinase (beta-Ala-His) by complementation of an E. coli mutant. Further study, including the crystallization of the enzyme, has shown it to also be a non-specific dipeptidase. This group also includes enzymes from Streptococcus and Enterococcus. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0

>CP022059.2|ASE64430.1|2766_3780_+|acyltransferase
MENDKRIYKWDNVKLFLIFLVIFGHILDREASPSRLMETINFWIYSFHMPAFIFVSGLFSKHAIKQRKYLRLLSFVWLYLLAKLLITLANFAFANKMNFDLLNETGVPWYLLSLASFYLITIFLQRVQPKIMLPIIIVIGCASGYLPVEGFLSLGRTLGFFPFFYCGYLMDIQKLQTFLDHRKVKWAAIGVILSSFLFVNSQWSLATKFWGFLTGWASYAEISPAFEYSSFIQLFFYVAAALVSLSWFALLPKRKLPLSALGKDTLYPYLLHMPLIILLESGLQLDTLFKEWFTFRILALFFLALFILAITNMPVVKRGADYLFNPQSIMIPKKIYK
>CP022059.2|ASE64429.1|1577_2531_-|ABC-transporter-ATP-binding-protein
MIKFQNVSKVYQENAVLSDVNLTIQQGEFFVLVGPSGSGKTTTLKMINRLIEPTTGEVALNEQAVTNYPLRELRLKIGYVLQQIALFPNLTVAENIELIPEMKKWPKEQRRERTIELLKKVQLNPEEYLHRKPAALSGGEQQRIGILRAIAAEPEVILMDEPFSALDPISRHHLQRLVKELHQELASTIVFVTHDMNEALLLGERICIMDAGKIIQVDTPEAIQKHPKNNFVGQFFKQSSPELANYCGADLTAFLEAADETIEPVPTVFMETNLKEIVQLINAQEKANLVEKQQVLGCITSKTITRFMEQLLESEGQ
>CP022059.2|ASE64428.1|59_1577_-|glycine/betaine-ABC-transporter-permease
MQALIETFFARKEEYLQALIEHMQLSFISLLFAALIAIPLAIYLTSHRKLAESLLQVTGIFQTIPSLALLGLLIPLIGIGRPPAIVALVIYALFPILQNTYTGLTEIDPSLEEAAEAFGMSKKEKLFKFELQMALPFIISGIRTATVLIIGTATLAALIGAGGLGTFILLGIDRNNLSLIFIGALSSAALAVLFNYGIHWLEKANGRRLIIGGTILGLLLGGSFFWNQQTSSKEKQLTIAGKLGAEPDIIINMYKALIEENSDIQVTLKPNFGKTTFLYNALKSDEIDLYPEFTGTVIETFLKNPPQLDNQPQVVYEAARAGLKKQENLTLLKPMRYENTYAVAVKRSFAKAHQLKTISDLQKISNQLKAGFTLEFIDRQDGYKGLQEKYHLNLNVQSMEPALRYQAINNGEVNVIDAYSTDSELRQYDLVTLEDDQALFPPYQGAPLIKTATLEKYPELAEILNKLAGKISEEEMSEMNYQVNVEGQDPSIVAKDYLKEKNLLK
>CP022059.2|ASE64431.1|4883_5543_-|type-II-A-CRISPR-associated-protein-Csn2
MRVNFSLLEEPIEIEKATFLTIKDVQTFAHLVKLIYQYDGENELKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGITVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA
>CP022059.2|ASE64432.1|5543_5873_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRLLLMFDMPTDTASDRKAYRKFRKFLINEGFIMHQFSVYSKILLNDTANKAMLARLKQNNPQRGLITLLNVTEKQFSRMIYLHGEQDNRVANSDERIVFLGEE
>CP022059.2|ASE64433.1|5869_6736_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNKHSKLSYKNNHLVFKAIDHQELIHLSEIDVLLLETTDISLTTMLLKRLIDEKILVLFCDDKRLPIGKILPFYGRHDSSLQLTRQLAWTEERKGQVWTAIIAQKITNQSLHLAQRDYGQKAAALLAMRAELRLFDPANREGHAARSYFNTLFGNDFTREQENDINAGLNYGYTLLLSIFARELVQTGCFTQLGLKHANQFNDFNLASDLMEPFRPLVDQIIYENRKEAFPIMKRKLFALFMNTYMYKKKQMFLTNIATDYTKHVVKVLNQEEEGVPEFGI
>CP022059.2|ASE64434.1|6736_10750_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKDYVIGLDIGTNSVGWAVMTEDYQLVKKKMPIYGNTEKKKIKKNFWGVRLFEEGHTAEDRRLKRTARRRISRRRNRLRYLQAFFEEAMTDLDENFFARLQESFLVPEDKKWHRHPIFAKLEDEVAYHETYPTIYHLRKKLADSSEQADLRLIYLALAHIVKYRGHFLIEGKLSTENISVKEQFQQFMIIYNQTFVNGESRLVSAPLPESVLIEEELTEKASRTKKSEKVLQQFPQEKANGLFGQFLKLMVGNKADFKKVFGLEEEAKITYASESYEEDLEGILAKVGDEYSDVFLAAKNVYDAVELSTILADSDKKSHAKLSSSMIVRFTEHQEDLKKFKRFIRENCPDEYDNLFKNEQKDGYAGYIAHAGKVSQLKFYQYVKKIIQDIAGAEYFLEKIAQENFLRKQRTFDNGVIPHQIHLAELQAIIHRQAAYYPFLKENQEKIEQLVTFRIPYYVGPLSKGDASTFAWLKRQSEEPIRPWNLQETVDLDQSATAFIERMTNFDTYLPSEKVLPKHSLLYEKFMVFNELTKISYTDDRGIKANFSGKEKEKIFDYLFKTRRKVKKKDIIQFYRNEYNTEIVTLSGLEEDQFNASFSTYQDLLKCGLTRAELDHPDNAEKLEDIIKILTIFEDRQRIRTQLSTFKGQFSAEVLKKLERKHYTGWGRLSKKLINGIYDKESGKTILGYLIKDDGVSKHYNRNFMQLINDSQLSFKNAIQKAQSSEHEETLSETVNELAGSPAIKKGIYQSLKIVDELVAIMGYAPKRIVVEMARENQTTSTGKRRSIQRLKIVEKAMAEIGSNLLKEQPTTNEQLRDTRLFLYYMQNGKDMYTGDELSLHRLSHYDIDHIIPQSFMKDDSLDNLVLVGSTENRGKSDDVPSKEVVKDMKAYWEKLYAAGLISQRKFQRLTKGEQGGLTLEDKAHFIQRQLVETRQITKNVAGILDQRYNANSKEKKVQIITLKASLTSQFRSIFGLYKVREVNDYHHGQDAYLNCVVATTLLKVYPNLAPEFVYGEYPKFQTFKENKATAKAIIYTNLLRFFTEDEPRFTKDGEILWSNSYLKTIKKELNYHQMNIVKKVEVQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVLFTHEKGKKPLIKQEILGITIMEKTRFEQNPILFLEEKGFLRPRVLMKLPKYTLYEFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKQCLLPNQSESLAYVEQHQPEFQEILERVVDFAEVHTLAKSKVQQIVKLFEANQTADVKEIAASFIQLMQFNAMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVVD
>CP022059.2|ASE64435.1|11222_11456_-|hypothetical-protein
MSETLIVNYLIKGRVKMNVEELVQKAKDLIGEGNVEHAQQFIEEHKDELGEHYHKITAMLADTTTDGLFDKIKGLFQ
>CP022059.2|ASE64436.1|11600_13016_-|dipeptidase-PepV
MTIDWTKEVEARKDDLLEDLQNLLRINSERDDAQATPEAPFGPGPVAGLKHMLAYGERDGFTVKNVDNYAGHIEYGEGDETLGIFGHMDVVPAGDGWETDPYEPVIKDGKIYARGASDDKGPSMAAYYAMKIIKELGLPVSKKIRFVVGSDEESGWGDMDYYFQHEEAPDFGFSPDAEFPIINGEKGNVTIRLTFRGGNGADYKLESFKSGLRENMVPGTADAVVTAASADEAASLAASFETFIKQEAKISGNAELSDKTVTFHVVGKGAHGASPQSGINAATFLATFLNDYSFAEGAYSFINTIAEFIHEDFYGEKLGVAFEDEKMGKLTMNAGIVNFDPENPENSLVTLNFRYPKGTSAEELQAKVQATVGETVTATQGDRNQEPHYVPVDDPLVATLLQVYEDHTGEKGQEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEFMELDDLFRAAAIYADAIYRLAK
>CP022059.2|ASE64437.1|13149_13923_-|rRNA-pseudouridine-synthase
MSQAIFLKERGMTMRLDKFLADVGIGSRKEIKQLLKKKVVTVNGDVVKEAKTQVNEETDQIALMGEILTYQKFFYYMLHKPQGVISATEDQRDETVIDLLTDQDYRADLFPVGRLDKDTEGLLLLTNDGQLAHQLLSPKKHVDKEYLAEVEGLVTAEDCQLFAQGFALKDGEIVKPSRLVIETINEEEGTSVVRLVIQEGKFHQVKRMLATVGKPVTYLKRLRMGELWLDETLELGGYRPLTEAELQQLQPKQSYLN
>CP022059.2|ASE64438.1|13992_15642_-|polysaccharide-biosynthesis-protein
MINQPNSVDQPILTNQEKMVKGSAWMTASNIISRMLGAIYIIPWYAWMGEHGNEANSLFSMGYTIYALFLMISTAGIPGAIAKQTSHYNSLNEYKISRQLFYRALQLMGGLGVVFAIVMYLASPALAALSGGGPELVPTMRSLSLAVLVFPSMSVIRGYFQGNQEMMPFALSQIVEQVARVFYMLLTAFIIMKVFEGNYVTAVTQATFAAFIGMLASFAVLGYYMYKQKPLFDYLEEHSANEHEIAPKELLIETFKEAIPFIVVGSGVTVFKLVDQFTFSNFMRLFTDYSDTQLRELFGIFNANPDKLTMIVVALATSISATGLPLITEAVTLKNHRELARLISNNLQLFVFVMLPATFGMIVLAQPLYTVFYMPDALGTSLLVQACYASLFLGLYMLVSNMLMGMYENRDAMRYLGIGLAVKLIVQFPAIRLFEVYGPLLATMIGFTVSCVLILRRIRQVTRFNYKLTLRRTLLMFCITVIMMIIALIFRQFLYLFLDPTRRFQAFIIVVIVAAAGGAFYGYSVLKIRLADRLLGKNAAKLRAKFNIK
>CP022059.2|AVK72504.1|15845_17372_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase
MTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTILDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAEAFINKKN
>CP022059.2|ASE64439.1|17438_18011_-|phospholipase
MKQFFQKGSKPNQLVVAFHGTGGNEYQLLTTIATLYPEASVLSYLGTEGVGEQRRFFAPLVNGALPRANFDERVTAFLEEVWQPQKLYDEVIFIGYSNGANFILGLLEKNPTIANTVILLHPSNLGYQYVSGEFATKVIVTTGAQDELSIPGQVLSLANQLKKHFPVDFLLVDGGHGLSEEEVTKIKEVL

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Crispr_ID: CP022059_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022059_2

2231014-2231314

Orphan

II-A,II-B

Consensus_repeat	Method
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	PILER-CR

4 spacers

The CRISPR arrays of CP022059_2

>merge|CP022059|2|2231014-2231314|CRT,CRISPRCasFinder,PILER-CR
GGTGATAGTTTGTTTTTAAACAACATGACTCTAAAACAGCACAAGCGATACGAAGAATGTAATAGGGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAAGCGGGGTTAGTAAATTTCGGATAGATACGTTTTGGTACCATTCTAAACAACATGACTCTAAAACTACTTGTAAATAACTACGATAGTTTAAACGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAGCTTGTCAGCGCCTGTATACGGAGTATGGGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|2|2|2231014-2231314|CRT
GGTGATAGTTTGTTTTTAAACAACATGACTCTAAAAC	AGCACAAGCGATACGAAGAATGTAATAGG
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCGGGGTTAGTAAATTTCGGATAGATA
CGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TACTTGTAAATAACTACGATAGTTTAAAC
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGCTTGTCAGCGCCTGTATACGGAGTATG
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|2|2|2231015-2231314|CRISPRCasFinder
GTGATAGTTTGTTTTTAAACAACATGACTCTAAAAC	AGCACAAGCGATACGAAGAATGTAATAGGG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCGGGGTTAGTAAATTTCGGATAGATAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TACTTGTAAATAACTACGATAGTTTAAACG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGCTTGTCAGCGCCTGTATACGGAGTATGG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP022059|2|2|2231080-2231314|PILER-CR
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AAGCGGGGTTAGTAAATTTCGGATAGATA
CGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	TACTTGTAAATAACTACGATAGTTTAAAC
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGCTTGTCAGCGCCTGTATACGGAGTATG
GGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP022059.2\|AVK72679.1\|2230767_2230866_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66381.1\|2239508_2240654_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
CP022059.2\|AVK72678.1\|2222591_2223497_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
CP022059.2\|ASE66373.1\|2229189_2230608_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
CP022059.2\|ASE66374.1\|2231471_2232335_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP022059.2\|AVK72680.1\|2232419_2234501_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
CP022059.2\|ASE66372.1\|2228179_2229193_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
CP022059.2\|ASE66366.2\|2218614_2221038_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
CP022059.2\|ASE66376.1\|2235094_2235664_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
CP022059.2\|ASE66371.1\|2226441_2228175_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
CP022059.2\|ASE66367.1\|2221143_2221275_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66377.1\|2235796_2236312_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
CP022059.2\|ASE66379.1\|2237746_2238871_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
CP022059.2\|ASE66375.1\|2234631_2234997_-\|DUF1033-domain-containing-protein	unknown	unknown	gnl\|CDD\|336361
CP022059.2\|ASE66978.1\|2237540_2237690_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66370.1\|2224678_2226445_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
CP022059.2\|ASE66368.1\|2221351_2222563_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
CP022059.2\|ASE66369.1\|2223618_2224599_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
CP022059.2\|ASE66380.1\|2239096_2239441_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|370163
CP022059.2\|ASE66378.1\|2236328_2237567_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949

Protein	Function_ID	Function_description	E-value
CP022059.2\|ASE66381.1\|2239508_2240654_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	5.37018e-179
CP022059.2\|AVK72678.1\|2222591_2223497_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
CP022059.2\|ASE66373.1\|2229189_2230608_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
CP022059.2\|ASE66374.1\|2231471_2232335_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.86487e-27
CP022059.2\|AVK72680.1\|2232419_2234501_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
CP022059.2\|ASE66372.1\|2228179_2229193_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
CP022059.2\|ASE66376.1\|2235094_2235664_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	4.84428e-15
CP022059.2\|ASE66371.1\|2226441_2228175_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
CP022059.2\|ASE66366.2\|2218614_2221038_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	2.52612e-175
CP022059.2\|ASE66377.1\|2235796_2236312_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	1.1162e-31
CP022059.2\|ASE66379.1\|2237746_2238871_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP022059.2\|ASE66375.1\|2234631_2234997_-\|DUF1033-domain-containing-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
CP022059.2\|ASE66370.1\|2224678_2226445_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
CP022059.2\|ASE66368.1\|2221351_2222563_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.21914e-122
CP022059.2\|ASE66369.1\|2223618_2224599_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
CP022059.2\|ASE66380.1\|2239096_2239441_-\|cysteine-desulfurase	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
CP022059.2\|ASE66378.1\|2236328_2237567_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.18762e-174

>CP022059.2|AVK72679.1|2230767_2230866_-|hypothetical-protein
MIEEREEILVAPKKIVRNASVLFGFCLRKLYT
>CP022059.2|ASE66373.1|2229189_2230608_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>CP022059.2|ASE66372.1|2228179_2229193_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>CP022059.2|ASE66371.1|2226441_2228175_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSSGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>CP022059.2|ASE66370.1|2224678_2226445_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEQQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVTQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>CP022059.2|ASE66369.1|2223618_2224599_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>CP022059.2|AVK72678.1|2222591_2223497_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>CP022059.2|ASE66368.1|2221351_2222563_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVNEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>CP022059.2|ASE66367.1|2221143_2221275_-|hypothetical-protein
MLFNFWRISAYFRRSWFCSRRLSVFERGAKIQSDFCPTLIFLK
>CP022059.2|ASE66366.2|2218614_2221038_-|DNA-translocase-FtsK
MAQKRSTNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLLFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPATPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>CP022059.2|ASE66374.1|2231471_2232335_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFVAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWTGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELTQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>CP022059.2|AVK72680.1|2232419_2234501_-|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTDQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>CP022059.2|ASE66375.1|2234631_2234997_-|DUF1033-domain-containing-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>CP022059.2|ASE66376.1|2235094_2235664_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLIRVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAG
>CP022059.2|ASE66377.1|2235796_2236312_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQRLAKAKFEFLY
>CP022059.2|ASE66378.1|2236328_2237567_+|MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDD
>CP022059.2|ASE66978.1|2237540_2237690_-|hypothetical-protein
MLVIKPVNIRFSFLFYMPIFFKIRKREKLKIQIVDNFSVYNLVIIFLFF
>CP022059.2|ASE66379.1|2237746_2238871_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>CP022059.2|ASE66380.1|2239096_2239441_-|cysteine-desulfurase
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>CP022059.2|ASE66381.1|2239508_2240654_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK

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Crispr_ID: CP022059_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP022059_3

2250839-2250946

Orphan

Consensus_repeat	Method
TTCGTGCAAATGATACAACCTGCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP022059_3

>merge|CP022059|3|2250839-2250946|CRISPRCasFinder
TTCGTGCAAATGATACAACCTGCCCTTCGGTCATCTTGTACTGTTCATCATCTACTCTGTCGCTTCGCGCCAGTCGTAGTGATTCGTGCAAATGACACAACCTGCCCT

>CP022059|3|3|2250839-2250946|CRISPRCasFinder
TTCGTGCAAATGATACAACCTGCCCT	TCGGTCATCTTGTACTGTTCATCATCTACTCTGTCGCTTCGCGCCAGTCGTAGTGA
TTCGTGCAAATGACACAACCTGCCCT

Protein	Signature genes	Signature genes Name	Protein_function
CP022059.2\|ASE66393.1\|2254885_2255176_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66385.1\|2244580_2246119_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223562
CP022059.2\|ASE66383.1\|2242743_2243613_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
CP022059.2\|ASE66388.1\|2247696_2248530_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
CP022059.2\|ASE66382.1\|2241997_2242747_+\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
CP022059.2\|ASE66384.1\|2243599_2244526_+\|metal-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238557
CP022059.2\|ASE66390.1\|2249248_2250319_-\|methionine-import-ATP-binding-protein-MetN-1	unknown	unknown	gnl\|CDD\|236863
CP022059.2\|ASE66394.1\|2256772_2258581_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
CP022059.2\|ASE66391.1\|2251328_2251535_+\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66396.1\|2259853_2261560_-\|heme-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
CP022059.2\|ASE66392.1\|2253467_2253659_+\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66389.1\|2248549_2249230_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
CP022059.2\|AVK72682.1\|2253746_2254712_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|AVK72681.1\|2251775_2253266_+\|PcfV	unknown	unknown	gnl\|CDD\|372986
CP022059.2\|ASE66395.1\|2259023_2259857_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
CP022059.2\|ASE66979.1\|2240810_2241785_-\|ribose-phosphate-pyrophosphokinase-1	unknown	unknown	gnl\|CDD\|235039
CP022059.2\|ASE66386.1\|2246266_2246374_-\|hypothetical-protein	unknown	unknown	unknown
CP022059.2\|ASE66387.1\|2246488_2247682_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349940
CP022059.2\|AVK72683.1\|2255223_2256504_-\|aminoacyltransferase	unknown	unknown	gnl\|CDD\|367067
CP022059.2\|ASE66397.1\|2261660_2262212_-\|ECF-type-riboflavin-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|184218

Protein	Function_ID	Function_description	E-value
CP022059.2\|AVK72683.1\|2255223_2256504_-\|aminoacyltransferase	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	9.27394e-176
CP022059.2\|ASE66385.1\|2244580_2246119_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.093e-165
CP022059.2\|ASE66383.1\|2242743_2243613_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	4.30887e-76
CP022059.2\|ASE66388.1\|2247696_2248530_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	5.02051e-107
CP022059.2\|ASE66382.1\|2241997_2242747_+\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	2.54065e-104
CP022059.2\|ASE66384.1\|2243599_2244526_+\|metal-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238557	cd01137, PsaA, Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	7.59038e-124
CP022059.2\|ASE66390.1\|2249248_2250319_-\|methionine-import-ATP-binding-protein-MetN-1	gnl\|CDD\|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	8.08033e-168
CP022059.2\|AVK72681.1\|2251775_2253266_+\|PcfV	gnl\|CDD\|372986	pfam14264, Glucos_trans_II, Glucosyl transferase GtrII. This family includes glucosyl transferase II from the Shigella phage SfII, which mediates seroconversion of S. flexneri when the phage is integrated into the host chromosome.	3.44572e-32
CP022059.2\|ASE66396.1\|2259853_2261560_-\|heme-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	3.94445e-89
CP022059.2\|ASE66394.1\|2256772_2258581_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP022059.2\|ASE66389.1\|2248549_2249230_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.97195e-88
CP022059.2\|ASE66397.1\|2261660_2262212_-\|ECF-type-riboflavin-transporter-substrate-binding-protein	gnl\|CDD\|184218	PRK13661, PRK13661, ECF-type riboflavin transporter substrate-binding protein.	3.25341e-93
CP022059.2\|ASE66395.1\|2259023_2259857_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.28434e-41
CP022059.2\|ASE66979.1\|2240810_2241785_-\|ribose-phosphate-pyrophosphokinase-1	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
CP022059.2\|ASE66387.1\|2246488_2247682_-\|amidohydrolase	gnl\|CDD\|349940	cd08019, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0

>CP022059.2|ASE66390.1|2249248_2250319_-|methionine-import-ATP-binding-protein-MetN-1
MIELKNISVTFQQKKQEIQAVQDVSLTIDKGDIYGIVGYSGAGKSTLVRVINLLQRPTAGTVIINKENILTFSKKELRQQRKKIGMIFQHFNLMKERTIFSNIDFSLKYSGLSKSERRQKISHLLELVGLSEKRDAYPSQLSGGQKQRVAIARALANDPEILLCDEATSALDPKTTGQILALLKKLNQELNLTIVLITHEMQVVKEICNKVAVMENGCVVESNDIVSIFSQPQQPLTKDFIRTATHIDQALTTILEHPKLADLDKNQELIEFSYVGDQTNEPLIAQLYSQYQVYTNILYGNVEIVQNVPIGHLIVVLSGDEAQRQQALAYLAKQGVRTNVLKTYQQTKQKQNLQVI
>CP022059.2|ASE66389.1|2248549_2249230_-|ABC-transporter-permease
MYQLFEKYFPNVVQLKQEFLQSTWETVYMVFWTALIAGVLGVLLGVVLVSTGPSGVLKNPPLYSILEKIINVCRSIPFIIMLALIQPLTRILAGTTIGTTAALVPLVIGVIPFFARQIENALLEVDPGVIEAAEAMGTSPLGIIFRVYLIEGLPSIIRVSAVTIINLIGLTAMAGAIGAGGLGNLAITRGYNRFQTDVTFMATLIILIMVFISQAISNQLIKKTSH
>CP022059.2|ASE66388.1|2247696_2248530_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKFSKLIGLIGVLAFTIAGCASGSAKDTKTETVKLGVVGTKNDEWESVKDRLKKKNIDLQLVEFTDYTQPNAALAEKEIDLNAFQHQIFLDNYNKEHGTKLVSIGNTVNAPLGIYANKLKDITKIKDGGEIAIPNDPTNGGRALILLQTAGLIKVDPAKQQLPTVSDITENKRQLKITELDATQTARALQDVDASVINSGMAVDAGYTPDKDAIFLEPVNEKAKPYVNIVVAREEDQENKLYQKVVEEYQQEETKKIIAETSKGANVPAWETFGKK
>CP022059.2|ASE66387.1|2246488_2247682_-|amidohydrolase
MSITTIQTIQEAIATEKEWIIHLRRHFHQYPEASLKEYETIKRIKEELLALAIPFVEVGETGVLATIEGGLGAGKTILLRADIDALELPDATGAAYASKNPGLNHACGHDGHAAALLGAAKVLKKHQDTFSGTIKLAFQPAEEIGAGARQFVEGNYLEAIDQVFGIHLDSSVPVGKLVATKGATNASCDIFKIEVSGQSSHVAQPQNGRDAVLAAASIVVELQKIVAREIDPLDSVVVGIGVLQAGTRYNIVANQATIEGTVRTFSQETRQFVLQRVEEIAHEIAQSHRTEIADFSVYAAANPLINEEQATNRAQQVASEIVGFENVVTDHPKSLGADDFADYLAVIPGIYGRVGSRNPENPATHFGHHHEQFDIDERALLLAAEYHVRYALNYLSE
>CP022059.2|ASE66386.1|2246266_2246374_-|hypothetical-protein
MFFVLTDKLTRKVAPDSLRTDEALLWSRAINFFIA
>CP022059.2|ASE66385.1|2244580_2246119_-|ABC-transporter-ATP-binding-protein
MSILTIEHLTHRFGEKVLYEEASLQVNKGDHLGLTGQNGVGKSTLIKILTGEVLPDEGTIQWQKNCKIGYLDQHVSVEQSLTMVDFLKQAFQELFDKEAKLTKLYEEYSQTASEKLLEQAGKLQTDLDESNFYQIDTIIQDLANGLGLQAIGLDKKLGELSGGQRSKVILAKLLLEAPDVLLLDEPTNYLDDTHIQWLVRYLNNFEGSFLLVSHDYQFLNEVTNCIADIEFGKLTKYTGNVEKSFAQKEQNKQTYLKQYQAQQEKIEKMEAYIRKYKAGNRATMAKSRQKQLDRLERLTPPGSLTKPAIEFPYQGLVATQALTTQKLVVGYREPLLEPLDLMVHVGEKVALKGFNGIGKSTLIKTLTKVIPSLDGEFHYPLNTKIAYFTQDLAWPNEQLTPLDYLSDRFPDTTIKERRSHLARAGLPDKLAMQSLALLSGGEQTKVKLAELMMQTSNLLFLDEPTNHIDEAAKKSLQEAIHVYPGTVFLVSHEADFYEEIVDRVIDIEELVK
>CP022059.2|ASE66384.1|2243599_2244526_+|metal-ABC-transporter-substrate-binding-protein
MKKFSLFFLTLLAGLTLAACGNQAAEKKEKLAIVTTNSILSDLVKNVGQDKIELHSIVPIGTDPHEYEPLPEDIAKASEADILFFNGLNLETGGNGWFNKLMKTAKKVENKDYFSTSKNVTPQYLTSAGQEQTEDPHAWLDIENGIKYVENIRDVLVEKDPKNKDFYTENAKNYTEKLSKLHEEAKAKFADIPDDKKLLVTSEGAFKYFSKAYDLNAAYIWEINTESQGTPEQMTTIIDTIKKSKAPVLFVETSVDKRSMERVSKEVKRPIYDTLFTDSLAKEGTEGDTYYSMMNWNLTKIHDGLMSK
>CP022059.2|ASE66383.1|2242743_2243613_+|metal-ABC-transporter-permease
MIAAFIDGLFRYQFLQNALLTSIIVGLISGVIGSFIILRGMSLMGDAISHAVLPGVAVSYMFGFNYIFGASIFGLLAALSIGFITQKSPLKNDTAIGVVFSSFFALGIIFISFAKSSTDLYHILFGNVLAVADTDILITCVVGVIVLIFVALFYKELQLTSFDPTMAQAYGLNIQFFHYALMFLLTLVAVSSLQTVGTILVIAMLITPAATAYLLTNHLPTMIGLASTFGILSSVIGLFFSYSYNLASGATIVLTAALFFLLAFFFSPKKGLVFVNREKEMEESTNEKI
>CP022059.2|ASE66382.1|2241997_2242747_+|metal-ABC-transporter-ATP-binding-protein
MRKSFNLAVQALTVQYQGRTALNNIHVTIPSGKITGIIGPNGAGKSTFIKGLLGLIKTKERDVLLNNQAIDQQKTTIAYVEQRSALDLSFPISVFETVLLGTYPNLGLLKRPGKKEKQAAMAALKMVQLEDYAQRQIGELSGGQLQRVFIARVLAQGAEVIFLDEPFVGIDMSSEKVIMDILKSLKNQGKMIIIVHHDLHKVSHYFDELIVLKNRLIAAGPVEQTFTAETLQEAYGDLLGDLLIQGVAK
>CP022059.2|ASE66979.1|2240810_2241785_-|ribose-phosphate-pyrophosphokinase-1
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE
>CP022059.2|ASE66391.1|2251328_2251535_+|hypothetical-protein
MSTFFLRKKSFFFFYERAIDKLSSIRYSISCARDLYDFSKGTLTITRRSVAFENELYGFHFVAILELV
>CP022059.2|AVK72681.1|2251775_2253266_+|PcfV
MMKQLPTESKKFDLKNWCIENKAYLLLIILIYQVAVLSIGIINFPYLDDNARQVAGMTDFGTTYARWGSEFLSWFVQGSRHLTDLGLTTPILTGLILSLTSILAIYIINDQKISWGSSLVATLIGLNPWFLQCLSFRFDSPYMALSIFCSFLPFYWWQRNSFTFFLVSVFSLFVMFNTYQASSGIYIVIVLFLTFKQLLAGENFIALCKKVALAAIAYLLSIVSYLIELKFVPSATNNIGGSQALPSFHDIPSVAYQNSYHYFSELLNQSNRLWLLLLLLLLVLFFISHLSNSKINLGLSFLYCILYLGLASLLSFGIFIVYSRNIAGDAPRYIYGFAVFVTISMLSLFNNRQVKAIYLTSLLVASLLSYYILSFVLVYSSTLNYQKEAFNRQAAVLTDDLKNVVTNERKKVYLNTFFKNSTVYANTSRNYPILSKIVPPNDGLYFPNYVWFNTSSNLGVEMAPLTDTDMSKNQKVVSNHFYDIYTNNKEIFVFMK
>CP022059.2|ASE66392.1|2253467_2253659_+|hypothetical-protein
MLRTMRTRQKKLFLFSMILWLVEFLITRISDSFPGATPLFVVICLIQGILFTYFCLAFFYYPQ
>CP022059.2|AVK72682.1|2253746_2254712_-|hypothetical-protein
MSTIHEFPKNYERFIAQGEEALVEHNQIAALENFQQAYQLQQTPPVNQKIVQLLLEMDEADEALALAEAFQDSYFENLETAAIYMQIYSQSRRFIEGYILLKQLLQTNKITLAQQKTLEQQLMQVEEAYRQLETQQIQAIKRNLLVSDQLPVYQQLANIKTSLYLPKPVFVEVAKDLVMNQALSYFAREWFIEELALLQFSEPLTFLWYDNQPQTVLLEGKTGPLNTPIYSEIYTELRNRLENDDPIMLQHLEEEIRLHLAYLYPLAEKVISDPTIWVLGYLATYYPEYIEKELTEAKGHQIAAVQNVQQAIRTAFTQIML
>CP022059.2|ASE66393.1|2254885_2255176_-|hypothetical-protein
MENQVEVMTYAQLKEIMQALEANEAITEDTKVFIDTGWDSVQEVAPDAVSIEKVAKFTVADVLTNESFAGYSLEEKAEKMNAEGDLETAIIIRNLY
>CP022059.2|AVK72683.1|2255223_2256504_-|aminoacyltransferase
MLIYLTKKDCELFDMDQFSTLTEQEFTTFAMTHPAGNFLETPEMKHLLERRGWHCEYVGVKREGQLIAACILSKKKVKIGYAFDIDGGILMDYTDKKCVEAFFTGLKKYVKKNDGLYLTFTPNKQICLRDFNGGEVEKVNQETFDYFTSIGFEHQGFDVHNFDGAPRWLFVKDMAGLTEEELWKSYGKDAKYDIKKTWEYGVTTRELRYEELPLFKKLTEETSARRNFEDKDLAYYQAVYEEFGERAKFMVAELNFATYLENLHEKLRKLQETLNEVNEALIANPKSRKKNNQKREFEDEVRTVRKRIDEAKEMKTSDEPEILAGALFIVHPQEVVYLFSGTYEKYKQYYAPYLIQHKMLTYTVENNIPKYNFYGVDGVFDGSDGVLKFKQSFGGHVEELMGNFQWKAKPMKYALYHALKTIKEKV
>CP022059.2|ASE66394.1|2256772_2258581_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGMIGKENVTESLIQGLTKLEYRGYDSAGICVNDQSQQPHVVKAVGGIADLAAKLTPEIDGTVGIGHTRWATHGEPTVANAHPHVSSDQRFALVHNGVIENFEELKEQFLSGAHLIGDTDTEIVVQLIAHFAENGFSTKDAFKAALAEIKGSYAFALMDKMDPNTIYVAKNKSPLLIGLGEGFNVICSDAMAMIKETNQFVEIVDGEIVTVTADKVVIETPEGQVINREPFEAQLDLNDIEKGTYPFYMLKEIDEQPAVMRKIVQAYTQGEKVTLDEALLEKINQCDRIYIIACGTSYNAGWVGKSLIETIASIPVEVHLSSEFGYNMPILSEKPFFIFLSQSGETADSRQVLVQVNELGHPSLTLTNVAGSTLSREADDTLLLYAGPEIAVASTKAYTAQIAVLAILAKAIGEERQTLAAVSFDVAHELSVVAAVMETLIDEKQQMKALVEDYLTYTRNAFYIGRGVDYYVSMEAALKLKEISYIQAEGFAAGELKHGTIALIEEGTPVIGIVTDAKVAAHTRGNLKEVESRGARNIVIALESLAKPQDQLIIPDVHPLLSALVSIVPGQLLAYYATLQRGYDVDKPRNLAKSVTVE
>CP022059.2|ASE66395.1|2259023_2259857_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MSERQMLGYHPDSTWIHRLNGTSKLVFLIVVSVACMTTYDTRYLLGMSVVSLVLLKLSNIKWHQISFVIKFIAIFSLLNILTVYLFAPEYGVDLYQSRTVIWEGIGRFTLTQEELFYEFNLVLKYFCTIPLALIFLLTTNPSEFASSLNRIGVSYRISYAVALAIRYIPDIQEDFFNISLAQQARGYEMSKKGRLGQRIKGVAQIVLPLILSSLDRIETVSTAMELRRFGQKKNRTWYAQQPFHLRDFSVMILALCLLGISFWLFHVNGGRFYNPFQ
>CP022059.2|ASE66396.1|2259853_2261560_-|heme-ABC-transporter-ATP-binding-protein
MKKPIITFNNFSFQYHSQSEPTLKGIQLTIYEGEKVLIVGPSGSGKSTLAQCINGLIPNIYEGEIQGTATVAGKNIQETSLFDLSFDVGTVLQDTDGQFIGLTVAEDIAFALENDAVEQAEMKKAVHKWSEIVELNQLLQHRPQDLSGGQKQRVSMAGVLINQSKILLFDEPLANLDPRAGQETMTLIDTIQQETKATVLIIEHRLEDVLCESVDRIIVMNEGAIISDTTPDELLRQDTLTQQGIREPLYVTAMKYAGIDLTQVSHLDKLAEVSGEMVLPKMTQWSVQPSSVSAVKGAELLRLEQVSYQYDRHGEKVLDDFSVTIHHGEMISIVGKNGAGKSTLSKIICGFITPQSGKILWEGQDFSNYSIKERADKIGYVMQNPNQMISKKMIFEEVALGLVLRDVPQAEIEERVTNILHICGLYPFRNWPISALSFGQKKRVTIASILVLEPELLILDEPTAGQDFKHYTEMMTFLEELNRLGVTILMITHDMHLMLEYTTRALVVCDGRLLADATPVAVLTDEKLIQAASLKETSLFTFAKALGLENPLLFTEKFVAYDREVRFG
>CP022059.2|ASE66397.1|2261660_2262212_-|ECF-type-riboflavin-transporter-substrate-binding-protein
MKEKMSVKTIVAIGIGSAVFVILGRFVVIPTGIPNTNLETSYPFLALMSVVFGPVAGGLIGLIGHTLKDFTTYGSAWWSWIICSGIIGIIFGFAGRKMDLQHGEFTTNDMVRFNIFQAFGNIVVWGLIAPSLDILIYSEPASKVFTQGVFATVSNIVAVGIIGTLLMKAYASTRTKKGSLSKD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP022059_1	1.1\|4198\|30\|CP022059\|CRISPRCasFinder,CRT	4198-4227	30	MK867354	Synechococcus phage S-SCSM1, complete genome	151260-151289	6	0.8
CP022059_2	2.8\|2231249\|30\|CP022059\|CRISPRCasFinder	2231249-2231278	30	CP022016	Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence	290426-290455	6	0.8
CP022059_1	1.4\|4396\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4396-4425	30	NZ_CP016597	Bacillus cereus strain K8 plasmid pBCK802, complete sequence	47444-47473	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019095	Synechococcus phage ACG-2014f isolate Syn7803US34, complete genome	7535-7564	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019086	Synechococcus phage ACG-2014f isolate Syn7803US17, complete genome	7534-7563	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019106	Synechococcus phage ACG-2014f isolate Syn7803US50, complete genome	7304-7333	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019107	Synechococcus phage ACG-2014f isolate Syn7803US52, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019143	Synechococcus phage ACG-2014f isolate Syn7803C12, complete genome	7306-7335	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019103	Synechococcus phage ACG-2014f isolate Syn7803US44, complete genome	7852-7881	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019102	Synechococcus phage ACG-2014f isolate Syn7803US43, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019066	Synechococcus phage ACG-2014f isolate Syn7803C9, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019142	Synechococcus phage ACG-2014f isolate Syn7803C11, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019149	Synechococcus phage ACG-2014f isolate Syn7803C21, complete genome	7304-7333	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019105	Synechococcus phage ACG-2014f isolate Syn7803US4, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019098	Synechococcus phage ACG-2014f isolate Syn7803US39, complete genome	7306-7335	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019159	Synechococcus phage ACG-2014f isolate Syn7803C34, complete genome	7534-7563	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019123	Synechococcus phage ACG-2014f isolate Syn7803US7, complete genome	7301-7330	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019111	Synechococcus phage ACG-2014f isolate Syn7803US57, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019148	Synechococcus phage ACG-2014f isolate Syn7803C19, complete genome	7304-7333	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	NC_047712	Synechococcus phage ACG-2014f isolate Syn7803C7, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019090	Synechococcus phage ACG-2014f isolate Syn7803US24, complete genome	7534-7563	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019146	Synechococcus phage ACG-2014f isolate Syn7803C16, complete genome	7299-7328	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019152	Synechococcus phage ACG-2014f isolate Syn7803C25, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019093	Synechococcus phage ACG-2014f isolate Syn7803US30, complete genome	7304-7333	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019151	Synechococcus phage ACG-2014f isolate Syn7803C24, complete genome	7302-7331	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019150	Synechococcus phage ACG-2014f isolate Syn7803C22, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	NC_026927	Synechococcus phage ACG-2014f isolate Syn7803C90, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019097	Synechococcus phage ACG-2014f isolate Syn7803US37, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019045	Synechococcus phage ACG-2014f isolate Syn7803C6, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019037	Synechococcus phage ACG-2014f isolate Syn7803C58, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019099	Synechococcus phage ACG-2014f isolate Syn7803US3, complete genome	7306-7335	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019155	Synechococcus phage ACG-2014f isolate Syn7803C29, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019141	Synechococcus phage ACG-2014f isolate Syn7803C10, complete genome	7229-7258	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019053	Synechococcus phage ACG-2014f isolate Syn7803C80, complete genome	7306-7335	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019147	Synechococcus phage ACG-2014f isolate Syn7803C17, complete genome	7301-7330	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019100	Synechococcus phage ACG-2014f isolate Syn7803US40, complete genome	7304-7333	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019101	Synechococcus phage ACG-2014f isolate Syn7803US42, complete genome	8387-8416	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019085	Synechococcus phage ACG-2014f isolate Syn7803US13, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019096	Synechococcus phage ACG-2014f isolate Syn7803US36, complete genome	7956-7985	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019091	Synechococcus phage ACG-2014f isolate Syn7803US26, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019144	Synechococcus phage ACG-2014f isolate Syn7803C14, complete genome	7303-7332	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019145	Synechococcus phage ACG-2014f isolate Syn7803C15, complete genome	7264-7293	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019058	Synechococcus phage ACG-2014f isolate Syn7803C8, complete genome	7647-7676	7	0.767
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KJ019092	Synechococcus phage ACG-2014f isolate Syn7803US2, complete genome	7306-7335	7	0.767
CP022059_1	1.2\|4264\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4264-4293	30	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	690478-690507	8	0.733
CP022059_1	1.2\|4264\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4264-4293	30	NZ_CP045361	Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence	103642-103671	8	0.733
CP022059_1	1.2\|4264\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4264-4293	30	NZ_CP045319	Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence	226475-226504	8	0.733
CP022059_1	1.8\|4660\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4660-4689	30	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	150352-150381	8	0.733
CP022059_1	1.8\|4660\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4660-4689	30	MN694737	Marine virus AFVG_250M893, complete genome	29654-29683	8	0.733
CP022059_1	1.8\|4660\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4660-4689	30	KT630647	Salmonella phage SEN8, complete genome	20437-20466	8	0.733
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	311358-311387	8	0.733
CP022059_2	2.2\|2231117\|29\|CP022059\|CRT,PILER-CR	2231117-2231145	29	NZ_CP045296	Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence	93630-93658	8	0.724
CP022059_2	2.4\|2231249\|29\|CP022059\|CRT,PILER-CR	2231249-2231277	29	CP022016	Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence	290427-290455	8	0.724
CP022059_1	1.2\|4264\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4264-4293	30	NZ_CP042333	Bosea sp. F3-2 plasmid pB32-2, complete sequence	30149-30178	9	0.7
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	NC_048704	Pectobacterium phage Nepra, complete genome	13975-14004	9	0.7
CP022059_1	1.9\|4726\|30\|CP022059\|CRISPRCasFinder,CRT,PILER-CR	4726-4755	30	KY514265	Pectobacterium phage vB_PatP_CB3, complete genome	60666-60695	9	0.7
CP022059_2	2.6\|2231117\|30\|CP022059\|CRISPRCasFinder	2231117-2231146	30	NZ_CP045296	Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence	93629-93658	9	0.7

1. spacer 1.1|4198|30|CP022059|CRISPRCasFinder,CRT matches to MK867354 (Synechococcus phage S-SCSM1, complete genome) position: , mismatch: 6, identity: 0.8

atatgtaaatcataatgagcatttacattg	CRISPR spacer
atatggaaatcataatgaggattttccatc	Protospacer
***** ************* **** *  *

2. spacer 2.8|2231249|30|CP022059|CRISPRCasFinder matches to CP022016 (Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

agcttgtcagcgcctgtatacggagtatgg--	CRISPR spacer
agcctgtcatcgcctgtatacg--gcagggct	Protospacer
***.***** ************  *.* **

3. spacer 1.4|4396|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016597 (Bacillus cereus strain K8 plasmid pBCK802, complete sequence) position: , mismatch: 7, identity: 0.767

accattgacaacaatattcttttgttgcac	CRISPR spacer
acaattgacaacaatatccttttataaaaa	Protospacer
** **************.*****.* . *

4. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019095 (Synechococcus phage ACG-2014f isolate Syn7803US34, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

5. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019086 (Synechococcus phage ACG-2014f isolate Syn7803US17, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

6. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019106 (Synechococcus phage ACG-2014f isolate Syn7803US50, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

7. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019107 (Synechococcus phage ACG-2014f isolate Syn7803US52, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

8. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019143 (Synechococcus phage ACG-2014f isolate Syn7803C12, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

9. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019103 (Synechococcus phage ACG-2014f isolate Syn7803US44, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

10. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019102 (Synechococcus phage ACG-2014f isolate Syn7803US43, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

11. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019066 (Synechococcus phage ACG-2014f isolate Syn7803C9, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

12. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019142 (Synechococcus phage ACG-2014f isolate Syn7803C11, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

13. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019149 (Synechococcus phage ACG-2014f isolate Syn7803C21, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

14. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019105 (Synechococcus phage ACG-2014f isolate Syn7803US4, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

15. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019098 (Synechococcus phage ACG-2014f isolate Syn7803US39, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

16. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019159 (Synechococcus phage ACG-2014f isolate Syn7803C34, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

17. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019123 (Synechococcus phage ACG-2014f isolate Syn7803US7, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

18. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019111 (Synechococcus phage ACG-2014f isolate Syn7803US57, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

19. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019148 (Synechococcus phage ACG-2014f isolate Syn7803C19, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

20. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NC_047712 (Synechococcus phage ACG-2014f isolate Syn7803C7, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

21. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019090 (Synechococcus phage ACG-2014f isolate Syn7803US24, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

22. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019146 (Synechococcus phage ACG-2014f isolate Syn7803C16, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

23. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019152 (Synechococcus phage ACG-2014f isolate Syn7803C25, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

24. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019093 (Synechococcus phage ACG-2014f isolate Syn7803US30, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

25. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019151 (Synechococcus phage ACG-2014f isolate Syn7803C24, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

26. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019150 (Synechococcus phage ACG-2014f isolate Syn7803C22, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

27. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NC_026927 (Synechococcus phage ACG-2014f isolate Syn7803C90, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

28. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019097 (Synechococcus phage ACG-2014f isolate Syn7803US37, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

29. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019045 (Synechococcus phage ACG-2014f isolate Syn7803C6, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

30. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019037 (Synechococcus phage ACG-2014f isolate Syn7803C58, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

31. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019099 (Synechococcus phage ACG-2014f isolate Syn7803US3, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

32. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019155 (Synechococcus phage ACG-2014f isolate Syn7803C29, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

33. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019141 (Synechococcus phage ACG-2014f isolate Syn7803C10, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

34. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019053 (Synechococcus phage ACG-2014f isolate Syn7803C80, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

35. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019147 (Synechococcus phage ACG-2014f isolate Syn7803C17, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

36. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019100 (Synechococcus phage ACG-2014f isolate Syn7803US40, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

37. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019101 (Synechococcus phage ACG-2014f isolate Syn7803US42, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

38. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019085 (Synechococcus phage ACG-2014f isolate Syn7803US13, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

39. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019096 (Synechococcus phage ACG-2014f isolate Syn7803US36, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

40. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019091 (Synechococcus phage ACG-2014f isolate Syn7803US26, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

41. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019144 (Synechococcus phage ACG-2014f isolate Syn7803C14, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

42. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019145 (Synechococcus phage ACG-2014f isolate Syn7803C15, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

43. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019058 (Synechococcus phage ACG-2014f isolate Syn7803C8, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

44. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KJ019092 (Synechococcus phage ACG-2014f isolate Syn7803US2, complete genome) position: , mismatch: 7, identity: 0.767

ggatccatattctgatatgtacagagggat	CRISPR spacer
agatccagcttctgatatgtacaggagttt	Protospacer
.******  ***************..*  *

45. spacer 1.2|4264|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
ggagcgatggagcacgatggtctgcaccgc	Protospacer
 .************ * ********  .*

46. spacer 1.2|4264|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045361 (Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
taagcgatggcgcaggttggtcaggccgca	Protospacer
.********* *********** * .   *

47. spacer 1.2|4264|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045319 (Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
taagcgatggcgcaggttggtcaggccgca	Protospacer
.********* *********** * .   *

48. spacer 1.8|4660|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 8, identity: 0.733

atgcttcgaccagcaccaccaaagtctgca	CRISPR spacer
cccattcgaccagcaccatcaacgtctggt	Protospacer
 .  **************.*** *****

49. spacer 1.8|4660|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to MN694737 (Marine virus AFVG_250M893, complete genome) position: , mismatch: 8, identity: 0.733

atgcttcgaccagcaccaccaaagtctgca	CRISPR spacer
agatttccaccagcaccaccaaagtcaaag	Protospacer
* ..*** ****************** . .

50. spacer 1.8|4660|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KT630647 (Salmonella phage SEN8, complete genome) position: , mismatch: 8, identity: 0.733

atgcttcgaccagcaccaccaaagtctgca	CRISPR spacer
ccggcgagagcagcaccaccaaagtcagca	Protospacer
 .* .  ** **************** ***

51. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.733

ggatccatattctgatatgtacagagggat	CRISPR spacer
cgatccatattctgatttggacaggatatt	Protospacer
 *************** ** ****.. . *

52. spacer 2.2|2231117|29|CP022059|CRT,PILER-CR matches to NZ_CP045296 (Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.724

aagcggggttagtaaatttcggatagata	CRISPR spacer
tgccggggttagcaaatttcggatcgccg	Protospacer
 . *********.*********** * ..

53. spacer 2.4|2231249|29|CP022059|CRT,PILER-CR matches to CP022016 (Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.724

agcttgtcagcgcctgtatacggagtatg	CRISPR spacer
agcctgtcatcgcctgtatacggcagggc	Protospacer
***.***** ************* . .

54. spacer 1.2|4264|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042333 (Bosea sp. F3-2 plasmid pB32-2, complete sequence) position: , mismatch: 9, identity: 0.7

caagcgatggagcaggttggtctgctatga	CRISPR spacer
ggggcgttggagcaggttgggctgctggcc	Protospacer
 ..*** ************* *****.

55. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to NC_048704 (Pectobacterium phage Nepra, complete genome) position: , mismatch: 9, identity: 0.7

ggatccatattctgatatgtacagagggat	CRISPR spacer
caacccatattctgatctgtacagaataca	Protospacer
 .*.************ ********. .

56. spacer 1.9|4726|30|CP022059|CRISPRCasFinder,CRT,PILER-CR matches to KY514265 (Pectobacterium phage vB_PatP_CB3, complete genome) position: , mismatch: 9, identity: 0.7

ggatccatattctgatatgtacagagggat	CRISPR spacer
caacccatattctgatctgtacagaataca	Protospacer
 .*.************ ********. .

57. spacer 2.6|2231117|30|CP022059|CRISPRCasFinder matches to NZ_CP045296 (Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aagcggggttagtaaatttcggatagatac	CRISPR spacer
tgccggggttagcaaatttcggatcgccgg	Protospacer
 . *********.*********** * ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

76979 : 133759

Staphylococcus_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE64501.1\|76979_77939_+\|transposase	IS30 family transposase IS6770	NA	NA	NA	NA
ASE64504.1\|79319_79769_+	hypothetical protein	NA	NA	NA	NA
ASE64505.1\|80671_82015_-	PFL family protein	NA	NA	NA	NA
ASE64506.1\|82029_82296_-	ACT domain-containing protein	NA	NA	NA	NA
ASE64507.1\|82398_83067_-	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
ASE64508.1\|83412_84255_+	MATE family efflux transporter	NA	NA	NA	NA
ASE64509.1\|84839_85136_-	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
ASE64510.1\|85128_85593_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
ASE64512.1\|88077_88461_-	GntR family transcriptional regulator	NA	NA	NA	NA
ASE64513.1\|88701_89316_-	N-acetyltransferase	NA	NA	NA	NA
ASE64514.1\|89459_90020_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
ASE64515.1\|90095_91295_-	MFS transporter	NA	NA	NA	NA
ASE64516.1\|91737_92229_-	hypothetical protein	NA	NA	NA	NA
ASE64517.1\|92255_93401_-	galactonate dehydratase	Q6A202	Oenococcus_phage	1.2e-52	33.4
AVK72511.1\|93415_94783_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
ASE64518.1\|94807_95086_-	PTS galactitol transporter subunit IIB	NA	NA	NA	NA
ASE64519.1\|95104_95563_-	PTS galactitol transporter subunit IIA	NA	NA	NA	NA
ASE64520.1\|95574_96195_-	2-dehydro-3-deoxyphosphogluconate aldolase	NA	NA	NA	NA
ASE64521.1\|96205_98248_-	PRD domain-containing protein	NA	NA	NA	NA
ASE64522.1\|98529_99765_-\|transposase	IS256 family transposase	NA	NA	NA	NA
ASE64523.1\|99761_100346_-	DUF262 domain-containing protein	NA	NA	NA	NA
ASE64524.1\|100535_103568_-	restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	3.1e-18	23.3
ASE64525.1\|103797_104757_+\|transposase	IS30 family transposase	NA	NA	NA	NA
ASE64526.1\|105761_107252_-	xylulokinase	NA	NA	NA	NA
ASE64527.1\|107313_108621_-	xylose isomerase	NA	NA	NA	NA
ASE64528.1\|108725_109133_-	PTS mannose transporter subunit IIA	NA	NA	NA	NA
ASE64529.1\|109144_109627_-	PTS mannose/fructose/sorbose transporter subunit IIB	NA	NA	NA	NA
ASE66899.1\|109651_110464_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
AVK72512.1\|110456_111242_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
ASE66900.1\|111241_113308_-	family 31 glucosidase	NA	NA	NA	NA
ASE64530.1\|113673_114840_+	ROK family transcriptional regulator	NA	NA	NA	NA
ASE64531.2\|115348_115624_+	hypothetical protein	A0A0N9S8A3	Staphylococcus_phage	1.1e-10	40.9
ASE64532.1\|115729_116041_+\|transposase	IS3 family transposase	A0A0N9SIX5	Staphylococcus_phage	1.6e-23	65.6
ASE64533.1\|116780_116909_+	PTS lactose transporter subunit IIC	NA	NA	NA	NA
AVK72513.1\|117109_118243_-	pyridine nucleotide-disulfide oxidoreductase	V9VEY6	Lactococcus_phage	2.2e-06	26.7
ASE64535.1\|118345_119416_-	ammonium transporter	NA	NA	NA	NA
AVK72514.1\|119609_120014_-	NusG domain II-containing protein	NA	NA	NA	NA
ASE64536.1\|120065_120452_-	hypothetical protein	NA	NA	NA	NA
ASE64537.2\|120464_120638_-	50S ribosomal protein L32	NA	NA	NA	NA
ASE64538.1\|120988_122041_+	YibE/F family protein	NA	NA	NA	NA
ASE64539.1\|122027_122792_+	YibE/F family protein	NA	NA	NA	NA
ASE64540.1\|123424_123907_-	sugar permease	NA	NA	NA	NA
ASE64542.2\|123917_125420_-	PTS glucose transporter subunit IIBC	NA	NA	NA	NA
ASE64543.1\|125412_126120_-	putative N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
ASE64544.1\|126275_127094_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AVK72515.1\|127173_127380_-	hypothetical protein	NA	NA	NA	NA
AVK72739.1\|127392_127653_-	Sin recombinase	NA	NA	NA	NA
ASE64545.1\|127820_128294_+	recombinase family protein	A0A1V0E035	Clostridioides_phage	1.4e-10	38.0
ASE66901.1\|128339_129005_-	hypothetical protein	NA	NA	NA	NA
ASE64546.1\|129149_129272_-	hypothetical protein	NA	NA	NA	NA
AVK72516.1\|129301_129718_-	hypothetical protein	NA	NA	NA	NA
ASE64547.1\|129849_131028_-\|transposase	IS256 family transposase ISEf1	NA	NA	NA	NA
ASE64548.1\|131193_132402_-	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
ASE64549.1\|132580_133759_+\|transposase	IS256 family transposase ISEf1	NA	NA	NA	NA

DBSCAN-SWA_2

173864 : 193340

Streptococcus_phage(22.22%)

transposase,integrase,protease

attL 183101:183115|attR 199611:199625

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVK72522.1\|173864_175979_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	5.9e-117	38.7
ASE64584.1\|176397_176634_-	XRE family transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	1.6e-12	50.7
ASE64585.1\|176734_176887_+	DNA-binding protein	NA	NA	NA	NA
ASE64586.1\|177188_178448_+\|transposase	IS256 family transposase	NA	NA	NA	NA
ASE64587.1\|178492_179434_-	lysophospholipase	NA	NA	NA	NA
ASE66904.1\|179552_179894_+	hypothetical protein	NA	NA	NA	NA
ASE64588.1\|180009_180363_-	hypothetical protein	NA	NA	NA	NA
ASE64589.1\|180363_180888_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.3e-21	38.6
ASE64590.1\|181037_181298_-	DUF3102 domain-containing protein	J7KDG2	Streptococcus_phage	1.4e-12	49.4
ASE64591.1\|181652_182228_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
ASE64592.1\|182227_182416_+	hypothetical protein	NA	NA	NA	NA
ASE64593.1\|182492_183116_+	cysteine hydrolase	NA	NA	NA	NA
183101:183115	attL	NA	NA	NA	NA
ASE64594.1\|183253_184603_+	pyridine nucleotide-disulfide oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	5.8e-118	51.4
ASE64595.1\|184985_186357_+\|transposase	IS3-like element ISLla3 family transposase	A0A1B1P773	Bacillus_phage	3.5e-54	43.1
AVK72523.1\|186652_187249_-	HTH domain-containing protein	NA	NA	NA	NA
AVK72524.1\|187422_188382_-\|transposase	IS30 family transposase IS6770	NA	NA	NA	NA
ASE64596.1\|188539_189733_-	glycosyl transferase	M1H5V3	Paramecium_bursaria_Chlorella_virus	1.1e-43	32.4
ASE64597.1\|189769_190957_-	nucleotide sugar dehydrogenase	M1HV26	Paramecium_bursaria_Chlorella_virus	4.2e-96	48.6
AVK72525.1\|192740_193340_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	2.5e-28	35.6
199611:199625	attR	NA	NA	NA	NA

DBSCAN-SWA_3

631943 : 706967

uncultured_Mediterranean_phage(14.29%)

holin,integrase,tRNA,protease

attL 673980:673994|attR 709943:709957

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE64974.1\|631943_633215_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.9e-92	53.6
ASE64975.1\|633549_634731_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.7e-26	27.5
ASE64976.1\|634720_635410_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.6e-39	38.5
AVK72555.1\|635635_635719_+	hypothetical protein	NA	NA	NA	NA
ASE64977.1\|641807_642665_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
AVK72556.1\|642810_644118_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
ASE64978.1\|644137_645325_+	cystathionine gamma-synthase	NA	NA	NA	NA
ASE64979.1\|645629_646097_+	CtsR family transcriptional regulator	NA	NA	NA	NA
ASE64980.1\|646099_648595_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A0A8J958	Klebsiella_phage	1.9e-127	39.5
AVK72557.1\|648728_649763_+	FUSC family protein	NA	NA	NA	NA
ASE64981.1\|649943_650864_+	U32 family peptidase	NA	NA	NA	NA
ASE64982.1\|650891_652139_+\|protease	collagenase-like protease	Q6DW11	Phage_TP	8.7e-44	34.2
ASE64983.1\|652162_653725_+	PucR family transcriptional regulator	NA	NA	NA	NA
ASE64984.1\|653913_654138_+	hypothetical protein	NA	NA	NA	NA
ASE64985.1\|654412_655681_+	cytosine permease	NA	NA	NA	NA
ASE64986.1\|655700_656795_+	DUF917 domain-containing protein	NA	NA	NA	NA
ASE64987.1\|656795_658349_+	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
ASE66925.1\|658803_659277_+	hypothetical protein	NA	NA	NA	NA
ASE64988.1\|659254_660394_+	ImmA/IrrE family metallo-endopeptidase	B6SBZ6	Clostridium_virus	5.1e-43	33.2
ASE64989.1\|660416_660815_+	hypothetical protein	NA	NA	NA	NA
ASE64990.1\|660900_662250_+	glutathione-disulfide reductase	NA	NA	NA	NA
ASE64991.1\|662447_662810_+	dihydroneopterin aldolase	NA	NA	NA	NA
ASE64992.1\|662810_663296_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
ASE64993.1\|663289_663859_+	GTP cyclohydrolase I FolE	S4VV34	Pandoravirus	2.0e-32	49.1
ASE64994.1\|663862_664456_+	non-canonical purine NTP pyrophosphatase	A0A1K0ISQ7	Cassava_brown_streak_virus	1.5e-09	34.3
AVK72558.1\|664448_665240_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	5.4e-23	29.8
ASE64995.1\|665280_665382_+	hypothetical protein	NA	NA	NA	NA
ASE64996.1\|666151_667138_-	polyprenyl synthetase family protein	NA	NA	NA	NA
ASE64997.1\|667175_667733_-	heptaprenyl diphosphate synthase	NA	NA	NA	NA
ASE64998.1\|667744_668167_-	hypothetical protein	NA	NA	NA	NA
ASE64999.1\|668384_670331_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
ASE65000.1\|670608_671538_+	FMN-binding domain-containing protein	NA	NA	NA	NA
ASE65001.1\|671792_672860_+	FAD:protein FMN transferase	NA	NA	NA	NA
ASE65002.1\|672873_673821_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
673980:673994	attL	NA	NA	NA	NA
ASE65003.1\|674228_674570_+	cell surface protein	NA	NA	NA	NA
ASE65004.1\|674556_678402_+	WxL domain-containing protein	NA	NA	NA	NA
ASE65005.1\|678733_681730_+	WxL domain-containing protein	NA	NA	NA	NA
ASE65006.1\|682078_686770_+	WxL domain-containing protein	NA	NA	NA	NA
ASE65007.1\|686964_687108_-\|holin	putative holin-like toxin	NA	NA	NA	NA
ASE66926.1\|687337_687478_-\|holin	putative holin-like toxin	NA	NA	NA	NA
ASE65008.1\|687596_687740_-\|holin	putative holin-like toxin	NA	NA	NA	NA
ASE65009.1\|688069_689686_-	LytR family transcriptional regulator	NA	NA	NA	NA
AVK72559.1\|689720_689813_-	hypothetical protein	NA	NA	NA	NA
ASE65010.1\|690378_691008_+	chitin-binding protein	NA	NA	NA	NA
ASE65011.1\|691271_692264_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
ASE65012.1\|692402_692618_+	DNA-binding protein	NA	NA	NA	NA
ASE65013.1\|693024_693255_+	AbrB family transcriptional regulator	NA	NA	NA	NA
ASE65014.1\|693254_693596_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SAB3	Streptococcus_phage	4.2e-17	42.5
ASE65015.1\|693769_693949_+	hypothetical protein	NA	NA	NA	NA
ASE65016.1\|693957_697581_+	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	2.0e-48	24.5
ASE65017.1\|697747_701401_+	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	1.4e-65	24.8
ASE65018.1\|701450_702143_-	prepilin peptidase	NA	NA	NA	NA
ASE65019.1\|702251_703772_+	gluconate kinase	NA	NA	NA	NA
ASE65020.1\|703855_704575_+	DUF5105 domain-containing protein	NA	NA	NA	NA
ASE65021.1\|704702_705170_+	DNA starvation/stationary phase protection protein	C1KFH1	Lactobacillus_virus	1.0e-05	25.9
AVK72560.1\|705222_705330_-	hypothetical protein	NA	NA	NA	NA
ASE65022.1\|705391_705835_+	50S ribosomal protein L13	NA	NA	NA	NA
ASE65023.1\|705848_706241_+	30S ribosomal protein S9	NA	NA	NA	NA
ASE65024.1\|706346_706967_-\|integrase	integrase	A0A097BYJ7	Leuconostoc_phage	5.9e-09	26.1
709943:709957	attR	NA	NA	NA	NA

DBSCAN-SWA_4

725092 : 743838

Streptococcus_phage(94.74%)

integrase

attL 724841:724854|attR 742627:742640

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
724841:724854	attL	NA	NA	NA	NA
ASE65038.1\|725092_725407_+	DUF961 domain-containing protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
ASE65039.1\|725422_725809_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
ASE65040.1\|725837_727223_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AVK72563.1\|727225_727378_+	conjugal transfer protein	NA	NA	NA	NA
ASE65041.1\|727400_728606_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
ASE65042.1\|728648_728870_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
ASE65043.1\|728986_729484_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
ASE65044.1\|729458_729965_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
ASE65045.1\|729948_732396_+	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
ASE65046.1\|732398_734576_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
ASE65047.1\|734572_735574_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
ASE65048.1\|735570_736503_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
ASE65049.1\|736777_736864_+	tetracycline resistance protein	NA	NA	NA	NA
ASE65050.1\|736879_738799_+	tetracycline resistance ribosomal protection protein	A0A1S5SF82	Streptococcus_phage	0.0e+00	98.6
AVK72564.1\|738899_739085_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
ASE65051.1\|739144_739498_-	XRE family transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AVK72744.1\|739702_739774_+	hypothetical protein	NA	NA	NA	NA
ASE65052.1\|740002_740425_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
ASE65053.1\|740421_740652_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
ASE65054.1\|740877_741129_-	hypothetical protein	NA	NA	NA	NA
ASE65055.1\|741112_741316_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
ASE65056.1\|741397_742615_+\|integrase	site-specific integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
ASE65057.1\|742902_743838_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.4e-22	29.4
742627:742640	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1078702 : 1088442

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE65360.1\|1078702_1079341_+	thymidylate kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8
ASE65361.1\|1079360_1079690_+	hypothetical protein	NA	NA	NA	NA
ASE65362.1\|1079691_1080642_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.8e-34	33.0
ASE65363.1\|1080758_1081598_+	signal peptidase	NA	NA	NA	NA
ASE65364.1\|1081590_1081938_+	initiation-control protein YabA	M1PFV3	Streptococcus_phage	1.2e-16	37.6
ASE65365.1\|1082049_1082922_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
ASE65366.1\|1082936_1083599_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
ASE65367.1\|1083582_1084341_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
ASE65368.1\|1084466_1085585_+	DNA polymerase IV	NA	NA	NA	NA
ASE65369.1\|1085629_1086226_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
ASE65370.1\|1086258_1088442_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.0e-286	66.8

DBSCAN-SWA_6

1211631 : 1219548

Planktothrix_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE65472.1\|1211631_1212690_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
ASE65473.1\|1212689_1213646_+	ABC transporter ATP-binding protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	3.2e-06	23.9
ASE65474.1\|1213686_1214757_+\|transposase	transposase	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
ASE65475.1\|1215155_1215677_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
ASE65476.1\|1215790_1215991_+	50S ribosomal protein L35	NA	NA	NA	NA
ASE65477.1\|1216051_1216411_+	50S ribosomal protein L20	NA	NA	NA	NA
ASE65478.1\|1216457_1216808_-	hypothetical protein	NA	NA	NA	NA
ASE65479.1\|1216730_1216994_+	hypothetical protein	NA	NA	NA	NA
ASE65480.1\|1216905_1217265_+	DUF1304 domain-containing protein	NA	NA	NA	NA
ASE65482.1\|1217841_1218357_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	1.7e-38	48.8
ASE65483.1\|1218372_1219548_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.5e-85	47.7

DBSCAN-SWA_7

1577324 : 1586311

Staphylococcus_phage(25.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE65796.1\|1577324_1579721_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
ASE65797.1\|1579745_1580096_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
ASE65798.1\|1580178_1580409_+	hypothetical protein	NA	NA	NA	NA
ASE65799.1\|1580468_1580942_-	toxin	A0A097BY56	Enterococcus_phage	1.1e-60	71.2
ASE65800.1\|1580988_1581471_-	XRE family transcriptional regulator	R9QTP6	Staphylococcus_phage	1.2e-20	48.6
ASE65801.1\|1581639_1581822_+	hypothetical protein	NA	NA	NA	NA
ASE65802.1\|1581852_1582623_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	2.5e-33	57.0
ASE65803.2\|1582641_1583484_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	2.6e-31	31.0
ASE65804.1\|1583486_1583579_+	hypothetical protein	NA	NA	NA	NA
ASE65805.1\|1583571_1583943_+	hypothetical protein	NA	NA	NA	NA
ASE65806.1\|1583962_1584370_+	transcriptional regulator	NA	NA	NA	NA
ASE65807.1\|1584615_1585008_+	hypothetical protein	NA	NA	NA	NA
ASE65808.1\|1585020_1585533_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
ASE65809.1\|1585565_1585925_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
ASE65810.1\|1585942_1586311_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	4.6e-09	39.7

DBSCAN-SWA_8

2033318 : 2041962

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE66192.1\|2033318_2033891_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.4e-25	35.1
AVK72658.1\|2033887_2034919_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	2.2e-56	45.6
ASE66193.1\|2034920_2036360_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-49	33.0
AVK72659.1\|2036335_2038555_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.7e-146	39.9
ASE66194.1\|2038551_2039226_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
ASE66195.1\|2039226_2039478_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVK72660.1\|2039491_2040205_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
ASE66196.1\|2040356_2041481_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
ASE66197.1\|2041473_2041962_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.4e-19	42.0

DBSCAN-SWA_9

2156834 : 2209325

Enterococcus_phage(38.24%)

terminase,head,portal,capsid,tail,holin,integrase,tRNA

attL 2172237:2172255|attR 2209381:2209399

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE66294.1\|2156834_2158604_-\|tRNA	aspartate--tRNA ligase	A0A2K9L424	Tupanvirus	3.0e-13	30.3
ASE66295.1\|2158621_2159923_-\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	1.3e-21	26.4
ASE66296.1\|2159919_2160168_-	hypothetical protein	NA	NA	NA	NA
ASE66297.1\|2160280_2160727_-\|tRNA	D-aminoacyl-tRNA deacylase	NA	NA	NA	NA
ASE66298.1\|2160750_2162964_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-10	38.0
AVK72673.1\|2163178_2163931_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
AVK72674.1\|2163932_2164880_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
ASE66299.1\|2164895_2165381_-	DUF3013 domain-containing protein	NA	NA	NA	NA
ASE66300.1\|2165337_2166027_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
ASE66301.1\|2166143_2167421_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	3.1e-105	49.9
ASE66302.1\|2167748_2168027_+	hypothetical protein	NA	NA	NA	NA
ASE66303.1\|2168203_2168677_+	universal stress protein	NA	NA	NA	NA
ASE66304.1\|2168788_2169976_-	acetate kinase	NA	NA	NA	NA
ASE66305.1\|2170000_2171008_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
ASE66306.1\|2171136_2171490_-	hypothetical protein	NA	NA	NA	NA
ASE66307.1\|2171489_2171924_-	competence protein ComG	NA	NA	NA	NA
ASE66308.1\|2171913_2172381_-	type II secretion system protein	NA	NA	NA	NA
2172237:2172255	attL	NA	NA	NA	NA
ASE66309.1\|2172617_2172743_+	hypothetical protein	NA	NA	NA	NA
ASE66310.1\|2173039_2173981_-	ferrochelatase	NA	NA	NA	NA
ASE66311.1\|2174696_2174942_-	hypothetical protein	NA	NA	NA	NA
ASE66312.1\|2175040_2175241_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.6e-24	80.3
ASE66313.1\|2176087_2177347_-	LysM peptidoglycan-binding domain-containing protein	C9E2L1	Enterococcus_phage	3.3e-208	89.2
ASE66314.2\|2177359_2177740_-\|holin	holin	A0A097QQ04	Enterococcus_phage	1.1e-61	100.0
ASE66315.1\|2177750_2177873_-	XkdX family protein	NA	NA	NA	NA
AVK72675.1\|2177874_2178270_-	hypothetical protein	NA	NA	NA	NA
AVK72676.1\|2178288_2178741_-	hypothetical protein	C0LZY6	Enterococcus_phage	3.3e-17	40.3
ASE66316.1\|2178757_2179498_-	hypothetical protein	A0A1X9IGH6	Lactococcus_phage	1.2e-27	34.6
ASE66317.1\|2179503_2180949_-	peptidase M23	A0A1X9IGI5	Lactococcus_phage	9.0e-77	39.2
AVK72677.1\|2180948_2181671_-	hypothetical protein	C5IUK4	Streptococcus_phage	1.2e-42	39.2
ASE66318.1\|2181667_2186122_-\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	2.2e-89	49.0
ASE66319.1\|2186108_2186414_-	hypothetical protein	NA	NA	NA	NA
ASE66320.1\|2186482_2186881_-	hypothetical protein	NA	NA	NA	NA
ASE66321.1\|2186943_2187252_-	hypothetical protein	L0P8M2	Lactobacillus_phage	2.7e-07	77.1
ASE66322.1\|2187254_2187860_-\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
ASE66323.1\|2187879_2188272_-	hypothetical protein	NA	NA	NA	NA
ASE66324.1\|2188268_2188607_-	hypothetical protein	A0A1L2K255	Streptococcus_phage	5.3e-12	38.7
ASE66325.1\|2188603_2188879_-	hypothetical protein	NA	NA	NA	NA
ASE66326.1\|2188875_2189208_-	hypothetical protein	A0A1W6JNH7	Staphylococcus_phage	2.7e-08	38.5
ASE66327.1\|2189278_2190175_-\|capsid	capsid protein	U3PDP8	Lactobacillus_phage	2.3e-70	50.2
ASE66328.1\|2190187_2190841_-	hypothetical protein	NA	NA	NA	NA
ASE66329.1\|2190945_2191872_-\|head	phage head morphogenesis protein	A0A097QPZ9	Enterococcus_phage	1.8e-131	98.0
ASE66330.1\|2191864_2193349_-\|portal	phage portal protein	A0A097QPZ5	Enterococcus_phage	3.8e-139	99.6
ASE66331.1\|2193348_2194632_-\|terminase	PBSX family phage terminase large subunit	Q9AZ91	Lactobacillus_prophage	5.1e-156	65.0
ASE66332.1\|2194612_2195047_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.8e-44	64.5
ASE66977.1\|2195078_2195243_-	hypothetical protein	NA	NA	NA	NA
ASE66333.1\|2196294_2197284_-	hypothetical protein	NA	NA	NA	NA
ASE66334.1\|2197985_2198402_-	autolysin	D2IZ17	Enterococcus_phage	1.4e-67	99.3
ASE66335.1\|2198769_2199030_-	hypothetical protein	NA	NA	NA	NA
ASE66336.1\|2199309_2199735_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.5e-59	81.4
ASE66337.1\|2199752_2200052_-	hypothetical protein	D2IZY1	Enterococcus_phage	5.1e-43	89.9
ASE66338.1\|2200052_2200355_-	hypothetical protein	D2IZR3	Enterococcus_phage	2.2e-46	96.0
ASE66339.1\|2200358_2201240_-	helix-turn-helix domain-containing protein	A0A2P1CD59	Lactobacillus_phage	1.1e-24	58.5
ASE66340.1\|2201239_2201440_-	hypothetical protein	NA	NA	NA	NA
ASE66341.1\|2201444_2202086_-	hypothetical protein	U5U4M2	Lactobacillus_phage	4.8e-30	36.0
ASE66342.1\|2202090_2202825_-	single-stranded DNA-binding protein	A0A1W6JNQ5	Staphylococcus_phage	2.3e-20	29.9
ASE66345.1\|2203355_2203910_+	hypothetical protein	NA	NA	NA	NA
ASE66346.1\|2203890_2204097_-	hypothetical protein	NA	NA	NA	NA
ASE66347.1\|2204567_2204777_-	hypothetical protein	D2IZ57	Enterococcus_phage	1.8e-18	75.8
ASE66348.1\|2204831_2205020_+	DUF1508 domain-containing protein	NA	NA	NA	NA
ASE66349.1\|2205045_2205771_-	phage regulatory protein	A0A0P0IDD0	Lactobacillus_phage	2.2e-31	54.7
ASE66350.1\|2205809_2206121_-	hypothetical protein	NA	NA	NA	NA
ASE66351.1\|2206131_2206308_-	XRE family transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
ASE66352.1\|2206619_2206952_+	XRE family transcriptional regulator	A0A097QQ00	Enterococcus_phage	2.6e-35	69.1
ASE66353.1\|2206968_2207313_+	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	4.7e-40	70.8
ASE66354.1\|2207348_2208077_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	3.2e-22	49.5
ASE66355.1\|2208176_2209325_+\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	2.3e-38	30.7
2209381:2209399	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2273233 : 2360325

Enterococcus_phage(73.77%)

terminase,head,portal,capsid,tail,holin,integrase,tRNA

attL 2319423:2319449|attR 2360400:2360426

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
ASE66403.1\|2273233_2274163_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AVK72685.1\|2274163_2274910_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	8.1e-13	40.4
ASE66405.1\|2276832_2277792_-	epimerase	A0A1V0SKV4	Klosneuvirus	1.0e-47	36.2
ASE66406.1\|2277879_2278785_-	hypothetical protein	NA	NA	NA	NA
AVK72686.1\|2278781_2280248_-	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
ASE66981.1\|2280364_2280472_-	hypothetical protein	NA	NA	NA	NA
ASE66407.2\|2280532_2283412_-	glycosyl hydrolase family 25	U3PJ04	Lactobacillus_phage	2.8e-21	34.2
ASE66408.1\|2283440_2283839_-	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	2.1e-20	41.5
ASE66409.1\|2283844_2284699_-	LicD family protein	A0A1V0SD50	Indivirus	3.6e-09	50.9
ASE66410.1\|2284790_2285924_-	glycosyl transferase	NA	NA	NA	NA
AVK72687.1\|2285930_2287469_-	transporter	NA	NA	NA	NA
ASE66411.1\|2287609_2288584_-	glycosyl transferase family 2	A0A0F7L2F7	uncultured_marine_virus	2.5e-06	34.3
ASE66412.1\|2288570_2289644_-	dTDP-glucose 4,6-dehydratase	NA	NA	NA	NA
ASE66413.1\|2289656_2290361_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
ASE66414.1\|2290593_2291436_-	LicD family protein	NA	NA	NA	NA
ASE66415.1\|2291451_2292285_-	ammonia monooxygenase	F2Y1U7	Organic_Lake_phycodnavirus	4.1e-13	31.6
ASE66416.1\|2292404_2293802_-	sugar transferase	NA	NA	NA	NA
ASE66417.1\|2293907_2295209_-	hypothetical protein	NA	NA	NA	NA
ASE66418.1\|2295237_2297208_-	hypothetical protein	NA	NA	NA	NA
AVK72688.1\|2297241_2299383_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
ASE66420.1\|2299394_2302538_-	methyltransferase domain-containing protein	NA	NA	NA	NA
ASE66421.1\|2302527_2303745_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-08	24.0
ASE66422.1\|2303757_2304552_-	ABC transporter permease	NA	NA	NA	NA
ASE66423.1\|2304799_2305141_+	hypothetical protein	NA	NA	NA	NA
ASE66424.1\|2305214_2305565_-	DUF2304 domain-containing protein	NA	NA	NA	NA
ASE66425.1\|2305564_2306290_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
ASE66426.1\|2306348_2307248_-	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	3.5e-26	33.2
ASE66427.1\|2307283_2308312_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.9e-68	41.9
AVK72689.1\|2308336_2308909_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.4e-41	50.3
ASE66428.1\|2308921_2309788_-	glucose-1-phosphate thymidylyltransferase	I7I009	Enterobacteria_phage	6.1e-105	63.9
ASE66429.1\|2309909_2310623_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
ASE66430.1\|2310626_2311454_-	glycosyl transferase family 2	NA	NA	NA	NA
ASE66431.1\|2311453_2312242_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
ASE66432.1\|2312363_2313500_-	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
ASE66433.1\|2313610_2314519_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
ASE66434.1\|2314534_2315299_-	type I methionyl aminopeptidase	NA	NA	NA	NA
ASE66435.1\|2315473_2315917_+	flavodoxin	NA	NA	NA	NA
AVK72690.1\|2315991_2316465_-	tryptophan-rich sensory protein	NA	NA	NA	NA
ASE66436.1\|2316622_2317195_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
ASE66437.1\|2317445_2318684_+	aminopeptidase	NA	NA	NA	NA
ASE66438.1\|2318943_2319324_+	PH domain-containing protein	A6N235	Microbacterium_phage	2.5e-10	33.0
2319423:2319449	attL	NA	NA	NA	NA
ASE66439.1\|2319694_2320276_+	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	4.2e-65	99.5
ASE66982.2\|2320632_2322135_+	hypothetical protein	C9E2L4	Enterococcus_phage	6.3e-275	99.6
ASE66440.1\|2322198_2323491_-	peptidase M23	C9E2L3	Enterococcus_phage	1.3e-252	100.0
AVK72691.1\|2323552_2323933_-	transcriptional regulator	C9E2L2	Enterococcus_phage	1.1e-63	100.0
ASE66441.1\|2323945_2325205_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	3.7e-228	93.6
ASE66442.1\|2325210_2325414_-\|holin	holin	C9E2L0	Enterococcus_phage	1.2e-30	100.0
ASE66443.1\|2325410_2325638_-	hypothetical protein	A0A0S2MYL7	Enterococcus_phage	1.3e-30	98.6
ASE66444.1\|2325711_2327475_-	hypothetical protein	C9E2K8	Enterococcus_phage	1.8e-268	99.8
AVK72692.1\|2327659_2329675_-	hypothetical protein	C9E2K6	Enterococcus_phage	0.0e+00	100.0
ASE66445.1\|2329691_2330621_-\|tail	phage tail protein	C9E2K5	Enterococcus_phage	1.5e-178	99.4
ASE66446.1\|2330621_2334029_-\|tail	phage tail tape measure protein	A0A0S2MYN1	Enterococcus_phage	0.0e+00	97.8
ASE66447.1\|2334044_2334302_-	hypothetical protein	A0A097BYA4	Enterococcus_phage	7.0e-41	100.0
ASE66448.1\|2334394_2334745_-	hypothetical protein	A0A097BYB6	Enterococcus_phage	3.3e-57	100.0
ASE66449.1\|2334800_2335259_-\|tail	phage tail protein	C9E2K1	Enterococcus_phage	4.3e-73	95.4
ASE66450.1\|2335336_2335867_-\|tail	phage major tail protein, TP901-1 family	A0A097BY59	Enterococcus_phage	4.3e-93	99.4
ASE66451.1\|2335882_2336272_-\|capsid	phage capsid protein	A0A0S2MYG3	Enterococcus_phage	8.6e-67	99.2
ASE66452.1\|2336268_2336649_-	hypothetical protein	A0A0S2MYE9	Enterococcus_phage	7.9e-65	99.2
ASE66453.1\|2336623_2336959_-	hypothetical protein	A0A097BYB2	Enterococcus_phage	7.7e-56	96.4
ASE66454.1\|2336955_2337288_-	hypothetical protein	A0A097BY55	Enterococcus_phage	4.2e-54	100.0
ASE66455.1\|2337361_2338294_-\|capsid	phage major capsid protein	A0A1B1V000	Enterococcus_phage	8.7e-174	99.7
ASE66456.1\|2338306_2338906_-	DUF4355 domain-containing protein	A0A097BY91	Enterococcus_phage	3.5e-75	98.5
ASE66457.1\|2339100_2339322_-	hypothetical protein	A0A097BYA7	Enterococcus_phage	1.9e-34	98.6
ASE66458.1\|2339318_2339588_-	hypothetical protein	A0A097BY49	Enterococcus_phage	6.4e-45	98.9
ASE66459.1\|2339588_2340527_-\|head	phage head morphogenesis protein	A0A097BY50	Enterococcus_phage	4.5e-170	98.1
ASE66460.1\|2340531_2342070_-\|portal	phage portal protein	A0A097BY86	Enterococcus_phage	1.8e-285	99.2
ASE66461.2\|2342083_2343478_-\|terminase	terminase	A0A097BY88	Enterococcus_phage	1.2e-272	99.6
ASE66462.1\|2343464_2343938_-\|terminase	terminase small subunit	Q9XJG1	Enterococcus_phage	7.4e-20	51.4
ASE66463.1\|2344006_2344651_-	hypothetical protein	NA	NA	NA	NA
ASE66464.1\|2344901_2345321_-	transcriptional regulator	NA	NA	NA	NA
ASE66465.1\|2345321_2345534_-	hypothetical protein	D2IZL5	Enterococcus_phage	4.3e-28	87.7
ASE66466.1\|2345527_2345845_-	replicase	NA	NA	NA	NA
ASE66467.1\|2345845_2346349_-	hypothetical protein	A0A0E3T929	Enterococcus_phage	3.5e-20	42.7
ASE66468.1\|2346345_2346612_-	hypothetical protein	NA	NA	NA	NA
ASE66469.1\|2346608_2346803_-	hypothetical protein	NA	NA	NA	NA
ASE66470.1\|2346957_2347356_-	hypothetical protein	D2IZY8	Enterococcus_phage	2.7e-39	67.4
ASE66471.1\|2347339_2347519_-	hypothetical protein	D2IZY7	Enterococcus_phage	6.4e-25	93.2
ASE66472.1\|2347541_2347748_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	7.4e-25	96.8
ASE66473.1\|2347767_2348097_-	hypothetical protein	NA	NA	NA	NA
ASE66474.1\|2348109_2348637_-	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	1.2e-42	54.9
ASE66475.1\|2348626_2348935_-	hypothetical protein	D2IZR4	Enterococcus_phage	1.6e-44	90.9
ASE66476.1\|2348934_2349741_-	helix-turn-helix domain-containing protein	A0A2D1GQ66	Lysinibacillus_phage	2.3e-21	53.3
ASE66477.1\|2349744_2350386_-	hypothetical protein	U5U4M2	Lactobacillus_phage	1.8e-29	35.1
ASE66478.1\|2350382_2351321_-	hypothetical protein	A0A0S2MYB3	Enterococcus_phage	1.4e-67	47.8
ASE66479.1\|2351320_2352064_-	single-stranded DNA-binding protein	A0A2H4IYS6	uncultured_Caudovirales_phage	1.8e-25	33.2
ASE66480.1\|2352149_2352452_-	hypothetical protein	NA	NA	NA	NA
ASE66482.1\|2352611_2352803_+	DUF1508 domain-containing protein	NA	NA	NA	NA
ASE66483.1\|2353204_2353663_+	hypothetical protein	NA	NA	NA	NA
ASE66484.1\|2353725_2353926_-	hypothetical protein	D2J031	Enterococcus_phage	1.0e-07	45.9
ASE66485.1\|2354449_2354974_+	hypothetical protein	NA	NA	NA	NA
ASE66486.1\|2355085_2355334_-	hypothetical protein	A0A0S2MYC6	Enterococcus_phage	2.4e-38	91.5
ASE66487.1\|2355349_2356069_-	oxidoreductase	C9E2M3	Enterococcus_phage	4.0e-134	100.0
ASE66488.2\|2356150_2356384_-	DUF739 domain-containing protein	A0A0S2MYC3	Enterococcus_phage	7.8e-39	100.0
ASE66489.1\|2356542_2357115_+	transcriptional regulator	C9E2M1	Enterococcus_phage	1.1e-99	100.0
AVK72693.1\|2357089_2357605_+	toxin	A0A0S2MYA6	Enterococcus_phage	1.0e-86	100.0
ASE66490.1\|2357692_2358247_+	hypothetical protein	C9E2L9	Enterococcus_phage	4.3e-96	99.5
ASE66491.1\|2358288_2358489_+	hypothetical protein	A0A0S2MYA2	Enterococcus_phage	7.4e-30	100.0
ASE66492.1\|2358549_2359122_+	hypothetical protein	A0A1B1UZZ9	Enterococcus_phage	2.2e-82	97.4
AVK72694.1\|2359188_2360325_+\|integrase	site-specific integrase	A0A0S2MYI6	Enterococcus_phage	5.4e-210	99.2
2360400:2360426	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP022059

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection