CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
CP024099	Bacillus cytotoxicus strain CH_38 plasmid pCh38_53, complete sequence	0 crisprs	NA	0	0	0
CP024100	Bacillus cytotoxicus strain CH_38 plasmid pCh38_83, complete sequence	0 crisprs	TnsE_C	0	0	1
CP024098	Bacillus cytotoxicus strain CH_38 chromosome, complete genome	4 crisprs	cas3,csa3,DinG,cas2,cas1,cas9,cas14j,cas4,cas5,cas7,cas8b2,cas6,DEDDh,WYL	1	16	10

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

52014 : 59268

Bacillus_phage(33.33%)

integrase

attL 46122:46137|attR 62330:62345

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
46122:46137	attL	NA	NA	NA	NA
AWC31016.1\|52014_52734_-	DNA (cytosine-5-)-methyltransferase	A0A1I9KKE7	Lactobacillus_phage	7.4e-64	52.0
AWC31017.1\|53287_53887_-	hypothetical protein	A0A1Z1LZN4	Bacillus_phage	5.1e-10	35.6
AWC31018.1\|54116_54323_-	hypothetical protein	NA	NA	NA	NA
AWC31019.1\|55525_56140_+	DNA recombinase	A0A1V0E035	Clostridioides_phage	7.1e-15	32.5
AWC31020.1\|56256_57213_+\|integrase	integrase	A0A1B1P793	Bacillus_phage	1.2e-37	34.3
AWC31021.1\|57656_57995_+	hypothetical protein	NA	NA	NA	NA
AWC31022.1\|58033_58219_+	DNA-binding protein	A6M9A5	Geobacillus_virus	6.8e-14	64.9
AWC31023.1\|58695_59268_-	hypothetical protein	A0A0K2SUB9	Clostridium_phage	3.3e-14	44.4
62330:62345	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP024098

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CRISPR-Cas detection and classification

Crispr_ID: CP024098_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024098_1

1597520-1597648

Orphan

Consensus_repeat	Method
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP024098_1

>merge|CP024098|1|1597520-1597648|CRISPRCasFinder
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACGTATTTGCGTAGGGGCGTTTTTTATTGAAGGTCCTACTGTCGTTGTGTCTTCATAACTAGGGTGGTACCGCGATATTTTAATCGTCCCTACG

>CP024098|1|1|1597520-1597648|CRISPRCasFinder
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACG	TATTTGCGTAGGGGCGTTTTTTATTGAAGGTCCTACTGTCGTTGTGTCTTCAT
AACTAGGGTGGTACCGCGATATTTTAATCGTCCCTACG

Protein	Signature genes	Signature genes Name	Protein_function
CP024098.1\|AWC28377.1\|1603435_1604335_+\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|183549
CP024098.1\|AWC28372.1\|1597751_1599089_+\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
CP024098.1\|AWC28363.1\|1582300_1583533_-\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
CP024098.1\|AWC28366.1\|1588145_1589405_+\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
CP024098.1\|AWC28379.1\|1605265_1606939_+\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
CP024098.1\|AWC28368.1\|1591407_1593048_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
CP024098.1\|AWC30809.1\|1583674_1583863_-\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28371.1\|1595476_1597111_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
CP024098.1\|AWC28374.1\|1599766_1600405_+\|elongation-factor-G-binding-protein	unknown	unknown	gnl\|CDD\|319974
CP024098.1\|AWC28370.1\|1594489_1595407_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
CP024098.1\|AWC28381.1\|1608456_1609176_+\|DUF554-domain-containing-protein	unknown	unknown	gnl\|CDD\|377371
CP024098.1\|AWC28375.1\|1600466_1601858_-\|transposase	unknown	unknown	gnl\|CDD\|372705
CP024098.1\|AWC28365.1\|1585863_1586328_-\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28378.1\|1604832_1604931_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378838
CP024098.1\|AWC28364.1\|1584431_1585808_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|226656
CP024098.1\|AWC28367.1\|1589736_1591305_+\|Vga-family-ABC-F-type-ribosomal-protection-protein	unknown	unknown	gnl\|CDD\|223562
CP024098.1\|AWC28380.1\|1606972_1608235_+\|threonine-dehydratase	unknown	unknown	gnl\|CDD\|236318
CP024098.1\|AWC28373.1\|1599360_1599627_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|337191
CP024098.1\|AWC28369.1\|1593265_1594474_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341031
CP024098.1\|AWC28376.1\|1601980_1602517_-\|peptide-methionine-(S)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|376578

Protein	Function_ID	Function_description	E-value
CP024098.1\|AWC28381.1\|1608456_1609176_+\|DUF554-domain-containing-protein	gnl\|CDD\|377371	pfam04474, DUF554, Protein of unknown function (DUF554). Family of uncharacterized prokaryotic proteins. Multiple predicted transmembrane regions suggest that the region is membrane associated.	4.36588e-73
CP024098.1\|AWC28372.1\|1597751_1599089_+\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	0
CP024098.1\|AWC28363.1\|1582300_1583533_-\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
CP024098.1\|AWC28366.1\|1588145_1589405_+\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	0
CP024098.1\|AWC28379.1\|1605265_1606939_+\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
CP024098.1\|AWC28368.1\|1591407_1593048_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
CP024098.1\|AWC28374.1\|1599766_1600405_+\|elongation-factor-G-binding-protein	gnl\|CDD\|319974	cd16342, FusC_FusB, Fusidic acid resistance protein (FusC/FusB). The fusidic acid resistance protein FusC (FusB) mediates resistance to the antibiotic fusidic acid. Its C-terminal domain, which contains a zinc-binding site, interacts with EF-G with high affinity, promoting the dissociation of stalled ribosome#EF-G#GDP complexes that form in the presence of fusidic acid, thus allowing the ribosomes to resume translation.	2.03194e-116
CP024098.1\|AWC28371.1\|1595476_1597111_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.49597e-129
CP024098.1\|AWC28377.1\|1603435_1604335_+\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|183549	PRK12479, PRK12479, branched-chain-amino-acid transaminase.	0
CP024098.1\|AWC28370.1\|1594489_1595407_+\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	1.17556e-161
CP024098.1\|AWC28375.1\|1600466_1601858_-\|transposase	gnl\|CDD\|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.00627e-27
CP024098.1\|AWC28378.1\|1604832_1604931_+\|hypothetical-protein	gnl\|CDD\|378838	pfam12323, HTH_OrfB_IS605, Helix-turn-helix domain. This is the N terminal helix-turn-helix domain of Transposase_2 pfam01385.	0.000629588
CP024098.1\|AWC28364.1\|1584431_1585808_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	1.27967e-24
CP024098.1\|AWC28367.1\|1589736_1591305_+\|Vga-family-ABC-F-type-ribosomal-protection-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.27803e-113
CP024098.1\|AWC28380.1\|1606972_1608235_+\|threonine-dehydratase	gnl\|CDD\|236318	PRK08639, PRK08639, threonine dehydratase; Validated.	0
CP024098.1\|AWC28373.1\|1599360_1599627_+\|hypothetical-protein	gnl\|CDD\|337191	pfam08765, Mor, Mor transcription activator family. Mor (Middle operon regulator) is a sequence specific DNA binding protein. It mediates transcription activation through its interactions with the C-terminal domains of the alpha and sigma subunits of bacterial RNA polymerase. The N terminal region of Mor is the dimerization region, and the C terminal contains a helix-turn-helix motif which binds DNA.	0.00419013
CP024098.1\|AWC28369.1\|1593265_1594474_+\|MFS-transporter	gnl\|CDD\|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.4256e-102
CP024098.1\|AWC28376.1\|1601980_1602517_-\|peptide-methionine-(S)-S-oxide-reductase	gnl\|CDD\|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	1.35442e-94

>CP024098.1|AWC28371.1|1595476_1597111_-|polysaccharide-biosynthesis-protein
MSTSKVLKGTALLSGATMISRILGFIYFFPFQLLVGTQGVALYGYAYSWYGILLSFSTAGIPIAVSKFVAKYNALGDYSTSKKLYNSSVKLMLLMGFSGFFILFIGAPYISQFIIRSKAPDPKFIADVTLTMRALSFALIIVPAMSVTRGYFQGFQHMKPSAVSQVVEQIARVVFILAGSFVVTKLLGGSVASSVAVATFGAAVGAIASVSILIMYWKKYNHLKPPKGELKSRASTLPLKSIYMELLRYAIPIVFVGIAIPLYTLVDQYTVADALRALGEPLTTANAVFAYIANYAQKLIMIPASLATGFSLTIIPAITKSFTSGKQEELQEQITKIFQVLLFFTIPAAFGLASIAYDTFRMVYVSHDIAVGGSQYLISYAPSAVLSAIFTVSAAILQGIDYQRKTMIAFSVGILVKLIVNTPLLYVLGGHGAVLGTILGYLVSDAIMLYCIVKFAKFDIKETIKTVCLIIIYSGAMSAIVMALKAMIGWFIPGQSYIESLLIVIICGVVGGFVYLLFVLTSGLASRILGNRIQRLPILGKFIK
>CP024098.1|AWC28370.1|1594489_1595407_+|cysteine-synthase-A
MKLCKNVTELIGDTPVVRLSKFVPKDAADVYVKLEMFNPSRSVKDRAAYHLIHVAEEQGFIQPGDTIIEPTSGNTGIGLAMNAAAKGYKAILIMPDNMSKERMNLLKAYGAEVILTPAEQRMPGAIAKAIELQKQIPNSFIPQQFENPANPNIHRYTTALEIYEQMEGKLDAFVATAGTGGTITGTGETLKEKLPNLHIVVVEPKGSPVLSGGVPGPHKLVGTSPGFIPKNLNTEIYNEIIQIADEEALSTMRNLAKQEGLLVGPSSGASVYAAIMIAKRLGAGKKVLCIAPDTGERYLSMGLFE
>CP024098.1|AWC28369.1|1593265_1594474_+|MFS-transporter
MQAISKENVVTTPTIYRILFAISFGHFLNDSMQAVVPALFPILEKTMNLSYMQVGWIAFALNMTSSVMQPVFGMYSDKKPSPFLLPLGMFSSMLGMIGLAFAPNFIIVIISVLFIGLGSAVFHPEGARVAYMASGTKRGLAQAIYQVGGNTGNSLAPIFTAVIFVPLGQKGSLGFTAFAAVGILLLMYVSKWYKNELVSGAVKSKKRAALEAENAIVSAHIKFVIVLLIFLTFVRSWYGAGIGNFYQFYLIEHYGLSIKNAQYFVFAFMISGVLGTFFGGPLADRFGKKNIIVFSMLGSAPLALLLPHVSLLWVVPLFLCIGFISSSSFSVIVVYAQELVPGKVGMVSGLIVGLAFGLGALGAVVLGKLADIYSLQFIMVLCSCLPLIGLTSWLLPSDKKSV
>CP024098.1|AWC28368.1|1591407_1593048_-|peptide-ABC-transporter-substrate-binding-protein
MKKKTKRVAVLSLTLSLVLTACGQKQETTTNKDEKKVATKQILNIVETGEISTLDSSIATDGFSYAALNNVMEGLYMPGPGNKPVPGAAESYTLSEDGKTYIFKLRHSNWSNGDPVTAHDFEYAWKRAINPETASEYAHIMFDIKNAEKVNKKALPLDSFGVKALDDKTLEVQLEHPVPYFLGLMGFATFYPQNQKVVEAQGTNYGLEAANAVYNGPFVLNEWKHDTSYKMTKNPNYWDHKNVKLQEINVNIVKDTSAAVNLFESKQVDRITINSEFVDKYQNDPSLKKMARPSVTFFRLNQKNPLLANKNARKAISLSFDKKGITTTILNNGSIPANAFIPKGFVKGPDNKDFRSTSNVKVETSIKEAKKQWETAKKETNLQNVSLSIISTDESNDKKISEYLKGELEKNLPGLKITLNPLPVKAFLEREGNGDFEISLSTWGPDYPDPTTFLNMFVTDGPFNKMNYSNKQYDELMEKASSSLTTDLPARWKAFQDAEKILVEDDAAIAPIFQAGLIYLERPSVKGVVVRPFAGIYSYKWAYITE
>CP024098.1|AWC28367.1|1589736_1591305_+|Vga-family-ABC-F-type-ribosomal-protection-protein
MLLLEANRIKYYIQDRLLLDIDQLQIHQNARIGLVGRNGSGKTTLFQILAKEIVPEEGSIVQRARCELLPQLKQTDTTKSGGEVTQEYIQKAVLKDPELLLADEPTTNLDTGHIEWLEKKLGNWKGAFVIISHDRAFLDALCTTIWELDEGKIKVYTGNYSEYVKQKEIERQQEQLAYEKYEKKKKQLEEAVKLKEKKAERATKTPKKEGKLEPKITKPYFAKKQKKLQKTATAMITRLEKLGKVEKVKELPPLKMDLPNAETFKNRIILRVNDRIGKVGKRVLWKKASFHIRGGDKLAIIGANGSGKTTLVKQIMNQEYGIRFSPAVKVGYFSQNLNILDPAKSIIENVQSSSKQNETLIRTVLARMHFFREDVYKLVEVLSGGERVKVALTKLFLSDINTLILDEPTNFLDMTAVEALESLLKEYEGSVIFVSHDRRFIENIATRILTIHNQELGLFEGTYQQYKRTQVQQAQERKKDTRLLLETKLSEVLSRLSIEPSEKLEREFEKLLQEKRELDASE
>CP024098.1|AWC28366.1|1588145_1589405_+|GTPase-HflX
MEEFVQRAILVGVNLGHESDFQYSMEELANLAEACDVEVVGQVTQNLQRVNPSHYIGTGKIGEVAAYVKEVDANIVIFNDELSPSQIRNLEKDLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLVGLRESLGRQSGGVGTKNKGVGEKKLELDRRKIEEQISVLNKELEALVVQRKTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIFNGTIEKQVFEKDMLFATLETSVRNIELPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYSNPNYEQLIEITNQTLKQIGVENIPTIYAYNKSDMMDVEIPKTKKDRVYLSAKKQIGMEELVEMIRSHIYKEYTKCEMLIPYDQGQIVSYFNEYAHVICTSYENEGTKLSLECKISDFEKYKRFAI
>CP024098.1|AWC28365.1|1585863_1586328_-|hypothetical-protein
MKRKIFFLLTLLCIVLPIQVSAFTFQELPVASKSKQWYIEIDKSYNSNKQARQPKQGVYDTYSLFVKNIGKDVSNVSIEIVGNDPSAKTTFKPTVPHTNVSKSHTSFDYMVFPLYFTSHTFKVVMTWEEKEFTYNGHPESKSKKMKQTFIFTEE
>CP024098.1|AWC28364.1|1584431_1585808_+|N-acetylmuramoyl-L-alanine-amidase
MKKVISNVLAMTAALQVIMVPTTSFAAEKGFSDVPKSHWAYEAINDLANRNIIAGYDNGKFGLGDSVTREQVAALIYRALKPEAKAEYKNPYHDVSASTTMFPNEILALTEMGIFTGDENKNFRPKDSLTRAEMAMILQRAYHLKVKANHTFHDVDPNSWAKDAISALQSNGMAEGDGTGAFYPSKTVTREEYAQFLFNAEQSYLNLDLTLASNVTAEEIDNFLKKSRSDSPLIGHGQDFIAAQNEHGVNALYLAAHAILESGYGRSEIAYRKHNLFGLRAYDRDPFYHAKYLPTYRDSISYNANYVRERYLEKGAIYYNGPTLVGMNVKYASDPEWAGKIAGLMERIKPFDRNDYKNANRLPKNPHTLDVEALGNEIPYKDLGNREIAVQASGKYYKVPYPYDLKIKSIPDITQNEMGTLTNGSKVTVHREDPNGWVEFSMKDKQEKYWTLKSNLKM
>CP024098.1|AWC30809.1|1583674_1583863_-|hypothetical-protein
MPKSINFSAFIDWDCFRIETELSYIQTCIYEELSTKKRYHVYTDIPFLAIFLLAPFSVSLFL
>CP024098.1|AWC28363.1|1582300_1583533_-|aspartate-kinase
METIVQKFGGTSVGNIQRIQHVANLMIEEYEKGHNVVTVVSAMGKSTDKLVALATSITENPSKRELDMLLTTGEQVTISLLTMALQTKGYQAISLTGWQAGITTEPVHGNARITDIHTERIQSYLQEGTIVIVAGFQGLSEEKEITTLGRGGSDTTAVALAAALKAKKCDIYTDVTGVYTTDPRVVNNAYKLDEISYDEMLELANLGAGVLHPRAVEFAKNHNVVLEVRSSMEQENGTIVRGECNMEQQSIVKGIAFEDNITRVTIKGLEHDSLSTIFSTLAEAHINVDIIIQSITNEGTVHLSFSIHSNDLRETLEALKQNQETLHYESVEYENHLAKVSIVGSGMVSNPGVAAHMFSTLKEENIHVKMVSTSEIKISVVIDRLHLVDGVEALHQAFMTKVEPLVQMNK
>CP024098.1|AWC28372.1|1597751_1599089_+|sodium-dependent-transporter
MNSPQWTSKLGFVLAAAGSAIGLGAIWKFPYMAGIGGGGAFFLIFIGFTLLIGLPLLLAEFVIGRSTQKEAVDAYRQIAPKTLWPWLGKLGVVTCFILLSFYSVVGGWILLYLWNAITGRLWEGNGAYEATFGEIISNPYLAVGSQLLFILMTIFIVSKGVQNGVEKVNKYFMPALFVLFFILIIRALTLDGAGEGVRFFLQPDFSNVTSEIILYAMGQSFFSLSVGVAVMVTYSSYLPKEESLPRSAFSIVGLTLMITLLAGLAIFPVVFAFGMEPSQGPGLLFIVLPAIFSKMAFGKVFFVIFLLLFFFATVTSAISMLEISVASLTAKGNGRREKFAIIVGLLIFVVGIPSALSYGVLSDFKVFGKTVFDLADFAVSNVLMPLGVLLVSIFVPLKMKKDVLMRELGVSKHKGYTLFILWLFLLRYIAPVAIIIVFLNVIGVI
>CP024098.1|AWC28373.1|1599360_1599627_+|hypothetical-protein
MGYVKATAVLPESLIAEIQKYVQGETIYIPKQETEHYKWGTRSGGRKQIDMRNRKIKEAFENGIAIYQLAEEYFLSVETIKKIVYSKS
>CP024098.1|AWC28374.1|1599766_1600405_+|elongation-factor-G-binding-protein
MEAFIRSDQYNFIKSQTHILVHGHATANDRGVITALKSLAIEKVLHAFENLNSEQKELIETILAVENREDAEAFLLKLNPYVIPFQEVTPQALKKLFPKVKKLKLPEMEEVNMKEMSYLGWTDKGTGKRFIIAKKNNKLVGVQGTFQSINKKGICALCHGHEEVGMFLVEIKGDVPGTFVKKGNYICQDSIACNQNMTSLDKLHDFIERLKK
>CP024098.1|AWC28375.1|1600466_1601858_-|transposase
MFYNQKNLEITQNRKFYEAMYDQDHHLVRIEKEMNWNIVYTLVKPFYQSPVGRPSVDPLIIVKILLIQYVEGFRSVRFTCKQVKQNATYRWFLGIFPHANIPCHSTISKFLTHRIQGSSIWEDLFDHILHQIQKDGFLSRDIWIADETELKANANKRKREVWIQEVEVKEDFYTLEKGNKRRIEKGKKPFLPRPTKIETKRILKSPTDPDARLSVKHDARGRFAYFEHRMVDGLHNFIIDTHITPANVPGHRILRKRIECTKERLGYIPKEIALDAGYYNARLAEGLFQNNLFSYISYRRYASKEHPECKKNQFKQVHEDLYACPCGIPFSYKTTTRNGYHEYKPEKGSCTGCPFAKKTDRVLRISVHEEIYHKLRWQRLSDRGKILRFVRPSTVELSFAQSKELHGFRFARYRGVQKVTIQALLTAIIQNLIKWTKLLSLKEVGLYLTYQISDEIESETVTF
>CP024098.1|AWC28376.1|1601980_1602517_-|peptide-methionine-(S)-S-oxide-reductase
MSKKTFELATFAGGCFWCMVKPFDELPGIQKVVSGYTGGHISNPTYEQVKSGTSGHLEVVQITFDPSIFPYQKLLDLYWSQIDPTDDDGQFFDRGPSYRTAIFYHNETQKELAEKSKQLLATSGIFNEPIVTEIRPAAPFYEAEEYHQHFYKKNPKKYAQERKESGREDFIKTNWQKK
>CP024098.1|AWC28377.1|1603435_1604335_+|branched-chain-amino-acid-aminotransferase
MKKQYIYMNGELVEKEKAVVSVYDHGFLYGDGVFEGIRSYGGNVFCLKEHVKRLYESAKSILLTIPMTVEEMEKAVVQTLQKNGYADAYIRLIVSRGKGDLGLDPRSCEKPSVIIIAEQLKLFPQEFYDNGLSVVSVASRRNMPDALDPRIKSMNYLNNVLVKIEAAQAGALEALMLNQQGYVCEGSGDNVFVVKDGKVVTPPSYLGALEGVTRNSVIELCDKLGIPCEERPFTRHDVYVADEVFLTGTAAELIPVVKVDAREIGDGKPGEVTKQLTEAFKRLTRERGVRVPGLAESLA
>CP024098.1|AWC28378.1|1604832_1604931_+|hypothetical-protein
MLVNKVYKFRIYPNKGQEILKQVVDVLQVNTS
>CP024098.1|AWC28379.1|1605265_1606939_+|dihydroxy-acid-dehydratase
MRSDMIKKGFDKAPHRSLLKATGLKDEDFHKPFVAICNSFIEIIPGHKHLNEFGRLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAAMRINIPTVFVSGGPMAAGKTSKGEVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILATDSRREQLIQRAAESLKILMERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLAIAQEAGLDYDMNRIDVVSRKVPHLCKVSPASNWHMEDIDRAGGMSAILKELSRKEGVLHLDRITVTGKTLRENIADAEIQDKEVIHSLENPHSQEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPGMPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGEIALLQQGDIVCIDVEERLLEVKVSDEELAKRRKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLKMQNFD
>CP024098.1|AWC28380.1|1606972_1608235_+|threonine-dehydratase
MVHKVKERVKIEDILMAHNCLKDIVNKTPLQRDAVLSEKYKCEVYVKREDLQVIRSFKIRGAYNLIQSLSKEKLQNGVVCASAGNHAQGVAYTCNLLEIPANIFMPTTTPKQKVSQVKFFGGDVADIVLVGDTFDSSFQEAQRYCEENGMTFVHPFDDPHVIAGQGTVAVEILHDTEKTIDYVFTAIGGGGLASGIGTYVKGVSPNTKVIGVEPKGAASMKEAFLQNENVTLEMIDSFVDGAAVKKVGKLTFETCKDVLDDIVLVPEGKICTTILELYKKNAIVAEPAGALSIAALDFYKDEIKGKTVVCVLSGGNNDIDRMQEMKERSLIYEGIKHYFIIQFPQRSGALREFLDKGLGPEDDITRFEYIKKHNKENGPALVGVELKHKEDYEPLIARFKENHIQFLELNKNPVLFDLLT
>CP024098.1|AWC28381.1|1608456_1609176_+|DUF554-domain-containing-protein
MVILGAIVNGICIIIGTLLGKVLSNIPESMKGTVMHAIGLAVTVLGLRMGMKSEIFLIVILSLVIGAVVGEWLCLEEKLQKLGNWLEKKVGSKGEGSISVGFVTATLIFAIGAMGVLGALDSGIRGNHNVLYTKAIIDGFISLILTTTLGIGVLFSAVPVILYEGGIALFATKIDRFVPEQLMNQFIIEMTATGGIMIFAIGLNLLGFIKIKVANLLPGILVVGMIVSIIYGYNLFLLK

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Crispr_ID: CP024098_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024098_2

2100280-2101039

orTypeII

Consensus_repeat	Method
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	PILER-CR
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	CRISPRCasFinder
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	CRT

11 spacers

cas2,cas1,cas9

The CRISPR arrays of CP024098_2

>merge|CP024098|2|2100280-2101039|PILER-CR,CRISPRCasFinder,CRT
GCCATAATTCCTCTTTAAATCTTGGTATGATATGATTTCGATGTTTATCCATCCACTCTTCGACAAGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTGTTTTGGGTTGCCGATGTAGAAGTAAAAAGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTACAAAAAGTGACTGAGGGGGCTTATAACGCCATAATTCCTCTTTAAATCTTGGTATGATATGATAGTGCAAGCAATCAAAAAAGGTGCAATTGAGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTGAAAATTTCGGTAATGTAAAGGTGTTTAGGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTCAGCACGTCTTTATTACAGGACAAACGGGGCCATAATTCCTCTTTAAATCTTGGTATGATATGATATTCCAATCGATGTATGGTGTGAGGAAGCTGCCATAATTCCTCTTTAAATCTTGGTATGATATGATGGTAGCAATCTAAAGCTATCATGTAGTATAGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTCGTCTTCCTCTACTTTTGGTTTCGGTGGGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTTTAATGATGTTGATAAGTTGCCCCGCATAGCCATAATTCCTCTTTAAATCTTGGTATGATATGATTAAGTATGACGACGGGACGCCATACACCGGGCCATAATTCCTCTTTAAATCTTGGTATGATATGAT

>CP024098|2|1|2100280-2101039|PILER-CR
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTCGATGTTTATCCATCCACTCTTCGACAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGTTTTGGGTTGCCGATGTAGAAGTAAAAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TACAAAAAGTGACTGAGGGGGCTTATAAC
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	AGTGCAAGCAATCAAAAAAGGTGCAATTGA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGAAAATTTCGGTAATGTAAAGGTGTTTAG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCAGCACGTCTTTATTACAGGACAAACGGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	ATTCCAATCGATGTATGGTGTGAGGAAGCT
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	GGTAGCAATCTAAAGCTATCATGTAGTATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCGTCTTCCTCTACTTTTGGTTTCGGTGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTTAATGATGTTGATAAGTTGCCCCGCATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TAAGTATGACGACGGGACGCCATACACCGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT

>CP024098|2|2|2100280-2101039|CRISPRCasFinder
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTCGATGTTTATCCATCCACTCTTCGACAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGTTTTGGGTTGCCGATGTAGAAGTAAAAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TACAAAAAGTGACTGAGGGGGCTTATAAC
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	AGTGCAAGCAATCAAAAAAGGTGCAATTGA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGAAAATTTCGGTAATGTAAAGGTGTTTAG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCAGCACGTCTTTATTACAGGACAAACGGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	ATTCCAATCGATGTATGGTGTGAGGAAGCT
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	GGTAGCAATCTAAAGCTATCATGTAGTATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCGTCTTCCTCTACTTTTGGTTTCGGTGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTTAATGATGTTGATAAGTTGCCCCGCATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TAAGTATGACGACGGGACGCCATACACCGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT

>CP024098|2|1|2100280-2101039|CRT
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTCGATGTTTATCCATCCACTCTTCGACAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGTTTTGGGTTGCCGATGTAGAAGTAAAAA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TACAAAAAGTGACTGAGGGGGCTTATAAC
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	AGTGCAAGCAATCAAAAAAGGTGCAATTGA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TGAAAATTTCGGTAATGTAAAGGTGTTTAG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCAGCACGTCTTTATTACAGGACAAACGGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	ATTCCAATCGATGTATGGTGTGAGGAAGCT
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	GGTAGCAATCTAAAGCTATCATGTAGTATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TCGTCTTCCTCTACTTTTGGTTTCGGTGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TTTAATGATGTTGATAAGTTGCCCCGCATA
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT	TAAGTATGACGACGGGACGCCATACACCGG
GCCATAATTCCTCTTTAAATCTTGGTATGATATGAT

Protein	Signature genes	Signature genes Name	Protein_function
CP024098.1\|AWC28801.1\|2111020_2111725_-\|Na+/myo-inositol-cotransporter	unknown	unknown	gnl\|CDD\|236699
CP024098.1\|AWC28797.1\|2105943_2106705_-\|DUF3959-domain-containing-protein	unknown	unknown	gnl\|CDD\|372477
CP024098.1\|AWC28792.1\|2098608_2099673_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|376220
CP024098.1\|AWC28793.1\|2100011_2100176_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
CP024098.1\|AWC28796.1\|2102398_2105632_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP024098.1\|AWC28788.1\|2094810_2095221_-\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28803.1\|2112853_2113447_-\|YhcN/YlaJ-family-sporulation-lipoprotein	unknown	unknown	gnl\|CDD\|131944
CP024098.1\|AWC28794.1\|2101193_2101502_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP024098.1\|AWC28795.1\|2101506_2102409_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP024098.1\|AWC28784.1\|2090789_2091368_-\|cysteine-dioxygenase	unknown	unknown	gnl\|CDD\|380416
CP024098.1\|AWC28786.1\|2091866_2093150_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
CP024098.1\|AWC28789.1\|2095375_2096380_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378848
CP024098.1\|AWC28787.1\|2093421_2094657_-\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
CP024098.1\|AWC28790.1\|2096392_2096926_-\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28785.1\|2091638_2091794_-\|DUF1540-domain-containing-protein	unknown	unknown	gnl\|CDD\|377869
CP024098.1\|AWC28800.1\|2110018_2110702_-\|thiaminase-II	unknown	unknown	gnl\|CDD\|381699
CP024098.1\|AWC28791.1\|2097001_2097304_-\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28802.1\|2112205_2112706_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
CP024098.1\|AWC28798.1\|2106961_2107381_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372952
CP024098.1\|AWC28799.1\|2107418_2109764_-\|translation-initiation-inhibitor	unknown	unknown	gnl\|CDD\|372436

Protein	Function_ID	Function_description	E-value
CP024098.1\|AWC28801.1\|2111020_2111725_-\|Na+/myo-inositol-cotransporter	gnl\|CDD\|236699	PRK10484, PRK10484, putative transporter; Provisional.	8.09642e-111
CP024098.1\|AWC28797.1\|2105943_2106705_-\|DUF3959-domain-containing-protein	gnl\|CDD\|372477	pfam13105, DUF3959, Protein of unknown function (DUF3959). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 260 amino acids in length.	6.19952e-160
CP024098.1\|AWC28793.1\|2100011_2100176_-\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	5.03974e-06
CP024098.1\|AWC28784.1\|2090789_2091368_-\|cysteine-dioxygenase	gnl\|CDD\|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.59854e-25
CP024098.1\|AWC28803.1\|2112853_2113447_-\|YhcN/YlaJ-family-sporulation-lipoprotein	gnl\|CDD\|131944	TIGR02898, Uncharacterized_lipoprotein_YlaJ, sporulation lipoprotein, YhcN/YlaJ family. YhcN and YlaJ are predicted lipoproteins that have been detected as spore proteins but not vegetative proteins in Bacillus subtilis. Both appear to be expressed under control of the RNA polymerase sigma-G factor. The YlaJ-like members of this family have a low-complexity, strongly acidic 40-residue C-terminal domain that is not included in the seed alignment for this model. A portion of the low-complexity region between the lipoprotein signal sequence and the main conserved region of the protein family was also excised from the seed alignment. [Cellular processes, Sporulation and germination].	1.73889e-47
CP024098.1\|AWC28794.1\|2101193_2101502_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.72822e-35
CP024098.1\|AWC28795.1\|2101506_2102409_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.65924e-100
CP024098.1\|AWC28792.1\|2098608_2099673_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|376220	pfam18801, RapH_N, response regulator aspartate phosphatase H, N terminal. Rap proteins consist of a N-terminal 3-helix bundle and a tetratricopeptide domain. This entry represents the conserved region of the C-terminal bundle.	1.0049e-18
CP024098.1\|AWC28786.1\|2091866_2093150_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.71525e-59
CP024098.1\|AWC28789.1\|2095375_2096380_-\|hypothetical-protein	gnl\|CDD\|378848	pfam12395, DUF3658, Protein of unknown function. This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam08874. There are two completely conserved residues (D and R) that may be functionally important.	4.46834e-35
CP024098.1\|AWC28787.1\|2093421_2094657_-\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	9.34877e-104
CP024098.1\|AWC28800.1\|2110018_2110702_-\|thiaminase-II	gnl\|CDD\|381699	cd19364, TenA_C_BsTenA-like, TenA_C proteins similar to Bacillus subtilis TenA. This family of TenA proteins belongs to the TenA_C class as it has a conserved active site Cys residue; the double Glu residues identified in the active site of TenA_E from the archaeon Pyrococcus furiosus is conserved in this family. TenA_C proteins (EC 3.5.99.2) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway. This family includes Bacillus subtilis TenA which has been shown to be a thiaminase II, catalyzing the hydrolysis of thiamine into HMP and 5-(2-hydroxyethyl)-4-methylthiazole (THZ), within thiamine metabolism. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	1.69765e-111
CP024098.1\|AWC28785.1\|2091638_2091794_-\|DUF1540-domain-containing-protein	gnl\|CDD\|377869	pfam07561, DUF1540, Domain of Unknown Function (DUF1540). This family has four conserved cysteines, which is suggestive of a metal binding function.	5.52411e-11
CP024098.1\|AWC28796.1\|2102398_2105632_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP024098.1\|AWC28802.1\|2112205_2112706_-\|N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	8.0744e-08
CP024098.1\|AWC28798.1\|2106961_2107381_-\|hypothetical-protein	gnl\|CDD\|372952	pfam14184, YrvL, Regulatory protein YrvL. YrvL prevents expression and activity of the YrvI sigma factor. It may function as an anti-sigma factor.	1.70694e-07
CP024098.1\|AWC28799.1\|2107418_2109764_-\|translation-initiation-inhibitor	gnl\|CDD\|372436	pfam13032, DUF3893, Domain of unknown function (DUF3893). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is typically between 123 and 144 amino acids in length. There is a single completely conserved residue E that may be functionally important.	1.0226e-25

>CP024098.1|AWC28793.1|2100011_2100176_-|hypothetical-protein
MGQFSVTKVGQIWLTIYKYLIGWCGYNALSDTPSICKERDKWIRRRLRMVIWKQ
>CP024098.1|AWC28792.1|2098608_2099673_-|tetratricopeptide-repeat-protein
MDANVITNTQITKQLNEWYQVMRAQHVLKARQLKKEIDTNLYQIEENPDSFIYYSLLDFRYNMLIGNFDCNLATTPVKKDVFLQYYYHFFKFIYAMETGNYNDAKEHHDYADELLKDISDVYEKAEFHYRTALYYYYIDQPILSIRYATKAKDFFSKNVGYEVKTAACENVLGISCIALKQFEAAEEYLLAAINTFKKQSEEDSVLKVKYNLGLLYADQNLSELAIRYLLDAFEDEEHDYKTMFLLAREHLKLGKSEIAKTYIEKGLKASTKEYYYHFSILQNMYSEHSLEKVESVVNEGVSYFKQQSLWGYVQEYAEALAVKLYNEKEEMKSNQYFYMSYEAKKILEEKGALK
>CP024098.1|AWC28791.1|2097001_2097304_-|hypothetical-protein
MKKSKAERKRDLEIVNLYHKKLTEEELEKLSVKFIEWKEGKLPYCELTEHIHECHKKNQIIWTRFHNMNDEFLIFQAKKELNLFSERDMEKEQYKRWNTF
>CP024098.1|AWC28790.1|2096392_2096926_-|hypothetical-protein
MQLIQCTKKLADMMELKTEKVDQRESNNLHSWHANLFTINRKKCVIVMNNVTRYHFIIYGVTKKDLRNFEALFQKNLVTNLLSDGVEPEVIEHYVKSSSPMQYAATNNRSILSQMNDAVFMVDHYFYAELVEKQKPFINIEKLNQNLNKTVMLKIPKYPADMMRDALNQHLIMSKNE
>CP024098.1|AWC28789.1|2095375_2096380_-|hypothetical-protein
MRDQLRKIIDNMSEEEVKSLLRLVLLQLELVAEHRDEEMIHMVAEISKQLIESQKPTLHIKDSEHVHIAFGDSSAGCLKHTLKKEGFHQDYVISLSDIFSVGPIFHLDDRKGQVARQEWLSSNLSTGDFYFEEEYLPRFLSSLEEMRSISQDTSVTIWKADNAHEHVGLCFALAMLKDKKNIRIIDASEAQKELLNKEYDICGTGELAPEDIAVILEQYKEKECLKEEARADLTKEWNALSTNTALLRIWKDGTVHSVVEDYFDEYIVRCAKEIGADKGFSKAAHVIGEVLGRVEQLVGDVFLEYRLQTLIKQNIFQAKGSLKAMRYYSVKLNR
>CP024098.1|AWC28788.1|2094810_2095221_-|hypothetical-protein
MYNYPNYPGIGYDQTMYSQYQGYGEEAMEPRESDYEEYRPDDAEDAPTSPPPSQAPSVPSTFASPVQSSNIRSWVCNCLGRWGYLRLHRPGPFGRDLWFFPTEVRRGGVSGYTWQAGRRRKVSYRYQQISNFMCFA
>CP024098.1|AWC28787.1|2093421_2094657_-|cytochrome-P450
MSVKNKVGRNIKDGIKLASPEFKEYAYEIYKESRKLQPILFVYKGELGTEWLITRYEDALSLLKDSRLKKNPENIFSQEKLKSLFSIENSDYLTKHMLNADPPDHNRLRALVQKTFTPKMISQLHNRIQHIADTLLDHVEQKRSFHFIRDFSFPLPIIVISEMLGIPKEDQAKFRIWSHAVIDSPEIPEEKIENEEKLSEFITYLQYLVDLKRKEPKEDLISRLIQAESEGGQLSAAELYSMIMLLIVAGHETTVNLMTNTVLALLENPDQLQLLKERPELIDSAIEEGLRYYSPVEVTTARWAAEPFHIHDKVIQKGDMVTISLASANRDETVFVNPDVFNITRENNRHIAFGHGGHFCLGAPLARLEAKIAIATLLKRMPRLRIKGKREDIKWEGNYLMRSLKELPLTF
>CP024098.1|AWC28786.1|2091866_2093150_-|MFS-transporter
MSVSAETNPKVGMSQVLKNRFVQGILISALCLQIGIWVRNFAVLLYVMEMTKGNAFAISMISVAEFAPIFIFSFIGGTFADRWKPRKTMIWCEALSSLSVFAVLLTLMFGTWKVVFFVTLISAILSQFSQPSGMKLFKQHLSAEEIQLAMSLYQTTFAIFMILGPILGTFVFQSFGIYISIVVTGVAFLLAAIVLLFLPKDVEMHAEKKQVSLLQEMADGIKYVLGKKALTLLGICFMAAGLGIGLIQPLGIFIVTEQLGLSKESLQWLLTVNGAGMIIGGALAMIFAKNVAPQKMLMIGLLAQAIGIGVIGFSTNLWITLTAQLFSGLALPCIQIGINTLIIQNSDTDFIGRVNGILSPLFTGSMVLTMSIAGSLKEMFSLSMLYEGTAVLFIVGLFVILPIYHLKPAVRAENQPAKEGSAIQQES
>CP024098.1|AWC28785.1|2091638_2091794_-|DUF1540-domain-containing-protein
MAQDVLCEVNNCKYWGNGNKCNADAIYVVSHKGKQASKTEETDCKTFTPEA
>CP024098.1|AWC28784.1|2090789_2091368_-|cysteine-dioxygenase
MLTCRKSELFQQFIHNVTASIENSKNEETIVCTIEKLLEKLLETKAWLPLEKQKANRNQYARHLLYKDPLDRFEVLALVWRDGQATPLHDHDGTWGVEGVFSGRIKVKNFLKIKQLEESIFQLKYLGHLYLGEGKTDKIIPPADCHILEIEPNEQVITIHIYGKKLEKFKVFIPTERKDIYRCKMKYIQYSS
>CP024098.1|AWC28794.1|2101193_2101502_-|CRISPR-associated-endonuclease-Cas2
MRILVFFDLPVMTKAERKAYTRFRKFLLKDGYTMLQFSVYTRVCNGEEGAQKHLRRLRQNIPNVNGAIRSLKVTEKQFESMDILLGVQTIDEKLGTNKTDFF
>CP024098.1|AWC28795.1|2101506_2102409_-|type-II-CRISPR-associated-endonuclease-Cas1
MAFRHIVIRNPSKLSTCDEQLLIKQEETVRIPLEDICTITIEDPAITITAALLSKCVEYHVELIVCDRKRLPAGILQPFHRHSRQKAVLDVQLGLGKPFKKRIWQQIVIRKLENQARCLELANKGEDAQKLYSISKSVESGDRTNREAYGAKVYFTALFGPNFYRREDDVRNISLNYGYSLVRSLTARALVRYGFNPSLGIFHDSQTNAFNLADDFMEVLRPFVDIIVALNVSDETEWDSKMREKLFSVLNIEAVWKEERQSITNGVEQMIKSYVSACRQNDASLLLLPELIALRQHTYE
>CP024098.1|AWC28796.1|2102398_2105632_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKYSIGLDIGIASVGWAVINEDIERIEDLGVRIFDVAEQPKTGASLSTPRRLARSTRKRLRRRRHRVERVRKFMIQKGLLTQVQMEQLYDWKDGDLDIWLVRVNALERKLSDREFARILVHFAKNRGFQSNRKSELQEEDNGAVLSAVQENKRLMEEKGYQTISEMLLYDEKFEGTKRNKGGEYTHVVARSDLKREIQLIFEKQRAYGHAFATMENEDKFLQIWSSQRPFATKDDIAKKIGNCTFEPKEKRAPKSTYTFERFRALDKLNRLRILSGTSPARSLTQEERDLILNSLFSKKEVKYKELRKLLKLNDEQRFNEIFYDPNEKIEKNENRTFLSLESQYKIRKILQKIEGKSLNDTYRPVDLDTIAYALTVFKDDQDIRDYLQNQYVASNGKKELNLANRKYNDELIEELLHLSFTKFGHLSLKALRNILPFMEQGIPYHQACEKAGYQFNKKVNREKQKLLPPVPAKDIVNPVVIRSLSQVRKVINGIIKRYGSPSSIYIELAREMGRGYKERKDLEKQYNKNRQMNEGAKKHILELRPEFGDPRGHDILKYKLWQEQDCRCAYSFKSIPIKQLFEIGYAEVDHIIPYSRSFDDSNNNKVLVLAAENQNKQNRTPYEWFGHDETKWQEFTSLVTTMKVSKKKKSLLLKKNFDEEQAEEFRSRHLNDTRYITRYIKTFIEDNLQFRMEEGKKQYVHTVNGAYTSLMRKRWGFNKNRQENDLHHALDAVIVAVSLPFKHKVSAYFKRREEYAHNQLKREGEFFPEPWPGFIHELEIRMMQDSENIKLAMESLNLKTYDESFIKELKPIFVSRMPKRAMRGQIHEETLKRVRGRTDDGYIRTVKKVKLDQIPFDKNGDFPMFGKETDMKTYEAIKSRYLESGKDKKKAFNTPLYKPAKNPENAPIIRSIKIEEKANRVVMLDEKTAADNASIVRTEVFRHKETGNYFLTPVYVADVLAKKVPDRLITTKKPYSEWRKITDEYEFLFSLYPNDLIRVKMPKEKGTKTHTGEKHVWQENFMYFKGVHSGSAGVRMIDHMNSFEDEIGVRKLVVFEKYQVDPLGRMNKVHGEKRHGI
>CP024098.1|AWC28797.1|2105943_2106705_-|DUF3959-domain-containing-protein
MKKLDVLLMLLSGLFPVAGIMKQIPLPLSLILGGLLFFTSFGSYYTKQTSSRVCSWLAYTIFITFLMGIWDQYVTMSSLLANAKIAACIALLPAILCFRTYGITFGLLALWGALLWDVKEVQSLAVLGRMMNLLTTEKMYLLLLIAGFLVGGLFANGFRRKNDKFKQETPNVLKQKKKRMRPTFHIRIPRLPKLRMKMLTFGRTPTQSKDKRPYESMREENIHAIQQEPQHEQQEPTTLGQTRMERRRNRYHV
>CP024098.1|AWC28798.1|2106961_2107381_-|hypothetical-protein
MVICTWIIAILLLSFTWLELVLLQIVGLQYESNQALILFFIVYIFTDLPLSLIVDNIPKALKSLDLIQTSKGWIPFLFDAGKTYILIMTIDYFMESITISWQGVFLFAIIRGSIGLKIKKDDPEPPSYSEVTKSLKNSE
>CP024098.1|AWC28799.1|2107418_2109764_-|translation-initiation-inhibitor
METIQLLAFKDVIDPLFEQTVFYVQWPKHWSSLLLEHNRPYELIKKFKLLNKRLYIMFSDILFIEHDPYKLAEDSLWIICLKPLSSEQLEYICRQWYAYIHNWKPTEMPGEVLLEWQPSAISKLSLLHDKKTFYIWVPALISHLFCERALHLSIGNKQYEEIPFYPLREQHRCEAMSEPIQDKKTKEYFSYIYRFELITRGIENMFLLKVSIGKRRFYQTANQYANYMIMKKRKGTVLVSNCHNEKDKFVTLKIEDARFGVNWSKAYRELQNVFMLKKQLDLVKIMQSPKKYIKGKRIRALVIYDENIFKVPGTKIKRGISRREKEVLLQAFHQRFPHCTYIPLCKNITINQNDELFPLYIREEMKEITLELWSSQRLTEIEKILFEEGLILEKRANHSYILNSKPQIILNIVTYNPKIIKQHPYRMDYCHKYKEDRIQSVIRAISSIPIQSFQTSLSLIEIEKCDGREKIDPKQVIREAFARTNRISQFIERLDGEEIKKEHIVRAIFSLLEKIGFRKRSWESMHPSHTYVSLSIEEIYNNQFVPILSKINEGEIVYKLYGSHEWRDFTSILLNVSAHETFLPQPSKRNDIGIQFKKYITEELTAIAEEAKKENKQVYFLIDASMREYWIESLQNEHMDLHDLPYISEEFQSLSNVTAIRINNQYDVPNYIMPLEKECDETELYVDQSGLYYSVNIYPLNDTGWKEQRILEIVVLGAKQEERDQIAKIITYMCKMSIIPGERPFIPFSMQMVKLIKKYITDIDLWQSSDELDTDWLIENE
>CP024098.1|AWC28800.1|2110018_2110702_-|thiaminase-II
MSFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAAKAIELKTTARMAHHAQNTYEAELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAAYEGHLGDIIAAILPCYWLYYEIGERLKECKPEEPIYQAWISAYGSDWFRTLVEEQIMRLDQIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR
>CP024098.1|AWC28801.1|2111020_2111725_-|Na+/myo-inositol-cotransporter
MLPGIIAFHLFGDQLKNADMAYPMLVIKILPIALSGFFAAVLFGAILSSFNGALNSSITLFTLDFYKPIFKKEASEKELVKVGRIFAITLGLIAVIVSPFILYAPSGLYNYLQEMFGFYNVPIIAAVVVGFFSKKVPASAPKIALVFHIILYALSKVFLGSINFLYILSVLFPACVIVMLVIGKLKPRETDFELFDANKVDLKPWKYAKVFSIFLIIFMLGAYVLFSPVGLAAQ
>CP024098.1|AWC28802.1|2112205_2112706_-|N-acetyltransferase
MSIHTENIKLVPYKEEYKEKIATFTLPSEQVQFTANPSDLLEKAKEDITKHVVVIVDQDVPVGIFALQTGERVTEYTNNPNALLLVSFSVDYEKQGKGYAKRGLRLLQEYVTAYFPEINEVVLAVNERNIPAQKVYLKVGFEDRGQRKMGPIGRQLILYLSIKKQE
>CP024098.1|AWC28803.1|2112853_2113447_-|YhcN/YlaJ-family-sporulation-lipoprotein
MKKCIYMLMICFAIAGCSVGTKDNAREKPEKRNVSMRNVTYTDNNKPNEKVADHLASLAASIPGVRDATAVVIGKYAVVGIDVKAKLDRSRVESIKYSVAESLKHDPKGANAVVVADVDTYERLKQMGNQIRHGKAGEGILDELAAIVGRVMPQVPNDMIENKETDPIKDNDKQLPKNEENELKKEQKDQSNHHLQR

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Crispr_ID: CP024098_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024098_3

2228723-2229210

Unclear

I-A

Consensus_repeat	Method
CTTTATATCCCACTACGTTCAGATAAAAC	CRISPRCasFinder
CTTTATATCCCACTACGTTCAGATAAAAC	CRT
CTTTATATCCCACTACGTTCAGATAAAAC	PILER-CR

7 spacers

cas2,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of CP024098_3

>merge|CP024098|3|2228723-2229210|CRISPRCasFinder,CRT,PILER-CR
CTTTCTATTCCACTACGTTCAGATAAAACCATCAAAATCAAAAACAGTTAAATTAGATGCAGATGACTTTATATCCCACTACGTTCAGATAAAACTAATAAAGCCGCCTAGACTGATACCAATTAATATTACCTTTATATCCCACTACGTTCAGATAAAACGTTCTCATTCGTACCAGATATGAGTGACGAATCGTTCTTTATATCCCACTACGTTCAGATAAAACTTGAATTATCGTTTACAATATCCTCATATTCATAGAACTTTATATCCCACTACGTTCAGATAAAACTTAGGACCCTCTCGTACACATACCTTCGAAAGAAACCTTTATATCCCACTACGTTCAGATAAAACTCTTTTAAAAGCTGTAGTATTTGTTTTTCGTATTCGACTTTATATCCCACTACGTTCAGATAAAACCGTGATGGACGATATGTCTTAATTCACGGCTCACAACTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|3|3|2228723-2229210|CRISPRCasFinder
CTTTCTATTCCACTACGTTCAGATAAAAC	CATCAAAATCAAAAACAGTTAAATTAGATGCAGATGA
CTTTATATCCCACTACGTTCAGATAAAAC	TAATAAAGCCGCCTAGACTGATACCAATTAATATTAC
CTTTATATCCCACTACGTTCAGATAAAAC	GTTCTCATTCGTACCAGATATGAGTGACGAATCGTT
CTTTATATCCCACTACGTTCAGATAAAAC	TTGAATTATCGTTTACAATATCCTCATATTCATAGAA
CTTTATATCCCACTACGTTCAGATAAAAC	TTAGGACCCTCTCGTACACATACCTTCGAAAGAAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TCTTTTAAAAGCTGTAGTATTTGTTTTTCGTATTCGA
CTTTATATCCCACTACGTTCAGATAAAAC	CGTGATGGACGATATGTCTTAATTCACGGCTCACAA
CTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|3|2|2228723-2229210|CRT
CTTTCTATTCCACTACGTTCAGATAAAAC	CATCAAAATCAAAAACAGTTAAATTAGATGCAGATGA
CTTTATATCCCACTACGTTCAGATAAAAC	TAATAAAGCCGCCTAGACTGATACCAATTAATATTAC
CTTTATATCCCACTACGTTCAGATAAAAC	GTTCTCATTCGTACCAGATATGAGTGACGAATCGTT
CTTTATATCCCACTACGTTCAGATAAAAC	TTGAATTATCGTTTACAATATCCTCATATTCATAGAA
CTTTATATCCCACTACGTTCAGATAAAAC	TTAGGACCCTCTCGTACACATACCTTCGAAAGAAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TCTTTTAAAAGCTGTAGTATTTGTTTTTCGTATTCGA
CTTTATATCCCACTACGTTCAGATAAAAC	CGTGATGGACGATATGTCTTAATTCACGGCTCACAA
CTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|3|2|2228789-2229210|PILER-CR
CTTTATATCCCACTACGTTCAGATAAAAC	TAATAAAGCCGCCTAGACTGATACCAATTAATATTAC
CTTTATATCCCACTACGTTCAGATAAAAC	GTTCTCATTCGTACCAGATATGAGTGACGAATCGTT
CTTTATATCCCACTACGTTCAGATAAAAC	TTGAATTATCGTTTACAATATCCTCATATTCATAGAA
CTTTATATCCCACTACGTTCAGATAAAAC	TTAGGACCCTCTCGTACACATACCTTCGAAAGAAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TCTTTTAAAAGCTGTAGTATTTGTTTTTCGTATTCGA
CTTTATATCCCACTACGTTCAGATAAAAC	CGTGATGGACGATATGTCTTAATTCACGGCTCACAA
CTTTATATCCCACTACGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP024098.1\|AWC28911.1\|2240451_2240796_+\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28893.1\|2212177_2212447_-\|PTS-lactose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
CP024098.1\|AWC28898.1\|2221425_2224956_-\|DUF4020-domain-containing-protein	unknown	unknown	gnl\|CDD\|238697
CP024098.1\|AWC28909.1\|2236845_2237547_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
CP024098.1\|AWC28904.1\|2230677_2231175_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
CP024098.1\|AWC28901.1\|2227235_2227619_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
CP024098.1\|AWC28899.1\|2225115_2225553_+\|DUF2512-domain-containing-protein	unknown	unknown	gnl\|CDD\|371204
CP024098.1\|AWC28900.1\|2225599_2226937_-\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
CP024098.1\|AWC28902.1\|2228237_2228492_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376564
CP024098.1\|AWC28906.1\|2233516_2234215_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
CP024098.1\|AWC28908.1\|2235097_2236846_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
CP024098.1\|AWC28905.1\|2231237_2233463_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP024098.1\|AWC28907.1\|2234211_2235105_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP024098.1\|AWC28895.1\|2215200_2217174_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
CP024098.1\|AWC28903.1\|2229433_2229697_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP024098.1\|AWC28910.1\|2239783_2240110_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
CP024098.1\|AWC28912.1\|2240920_2241250_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|169051
CP024098.1\|AWC28894.1\|2212459_2214565_-\|PTS-lichenan-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226234
CP024098.1\|AWC28896.1\|2217656_2219282_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|237894
CP024098.1\|AWC28897.1\|2219581_2220658_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	unknown	unknown	gnl\|CDD\|183614

Protein	Function_ID	Function_description	E-value
CP024098.1\|AWC28893.1\|2212177_2212447_-\|PTS-lactose-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	9.56231e-35
CP024098.1\|AWC28898.1\|2221425_2224956_-\|DUF4020-domain-containing-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	8.17817e-54
CP024098.1\|AWC28909.1\|2236845_2237547_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.0641e-22
CP024098.1\|AWC28904.1\|2230677_2231175_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.58631e-58
CP024098.1\|AWC28901.1\|2227235_2227619_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.47212e-43
CP024098.1\|AWC28899.1\|2225115_2225553_+\|DUF2512-domain-containing-protein	gnl\|CDD\|371204	pfam10710, DUF2512, Protein of unknown function (DUF2512). Proteins in this family are predicted to be integral membrane proteins, and many of them are annotated as being YndM protein. They are all found in Firmicutes. The true function is not known.	3.76655e-37
CP024098.1\|AWC28900.1\|2225599_2226937_-\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
CP024098.1\|AWC28902.1\|2228237_2228492_-\|hypothetical-protein	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	0.000135246
CP024098.1\|AWC28906.1\|2233516_2234215_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.84624e-29
CP024098.1\|AWC28908.1\|2235097_2236846_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	4.631e-10
CP024098.1\|AWC28905.1\|2231237_2233463_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.29099e-64
CP024098.1\|AWC28907.1\|2234211_2235105_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	4.74396e-53
CP024098.1\|AWC28895.1\|2215200_2217174_-\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
CP024098.1\|AWC28903.1\|2229433_2229697_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.02502e-27
CP024098.1\|AWC28910.1\|2239783_2240110_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	5.76195e-19
CP024098.1\|AWC28912.1\|2240920_2241250_-\|hypothetical-protein	gnl\|CDD\|169051	PRK07667, PRK07667, uridine kinase; Provisional.	4.84898e-47
CP024098.1\|AWC28894.1\|2212459_2214565_-\|PTS-lichenan-transporter-subunit-IIC	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.72064e-55
CP024098.1\|AWC28896.1\|2217656_2219282_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
CP024098.1\|AWC28897.1\|2219581_2220658_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	gnl\|CDD\|183614	PRK12595, PRK12595, bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed.	0

>CP024098.1|AWC28902.1|2228237_2228492_-|hypothetical-protein
MKDTTKYVGLDVSKEKIAVAIADEGREEPRYLGMIPHTPESLRKLIKKLGAVEHLKACYKAGSTGYGIYRLLFSLGVDCAVIAP
>CP024098.1|AWC28901.1|2227235_2227619_-|VOC-family-protein
MMIHKVGQIMLYVKDQDEAVQFWTEKMGFHLIAEEDNGKGFRWIEIAPTKEAETSIVLHNKEFIAKMQPELNLNTPSMLFFTENIEQLHKQLVDKKVAVGEIVNMPTGKAFNFADDEGNYFAIMEKS
>CP024098.1|AWC28900.1|2225599_2226937_-|D-serine-ammonia-lyase
MWEKMIKGKTIRKWTEENPILQQLIETSEVFWENPNYSSYEKARQDFVLTTEDVKEAEARLLRFAPYIAKVFPETKEMDGIIESPLVETMHMKQYLEDAFAQEMPGRFLLKCDNNLPISGSIKARGGIYEVLQHAEKLAIEHNLLCEEDHYAKLDSDRFREFFSQYSIAVGSTGNLGLSIGIMSAKLGFQVTVHMSADAKEWKKELLRNKGVTVVEYESDYSKAVEEGRKQAEQDPHCYFIDDENSKHLFLGYAVAASRVKQQLEDKNIRVDKDHPLFVYLPCGVGGGPGGVAFGLKLLFGDAVHCFFAEPTHSPCMLLGLVTGLHDEIAVQDFEIDNVTEADGLAVGRASGFVGKIMEPLLSGCYTVEDQQLYELLKAMVDTENIRLEPSALAAVYGSVQLYRQENYVKKHKLEGKMNRSTHMMWATGGGMVPKSVFDEYYQNQ
>CP024098.1|AWC28899.1|2225115_2225553_+|DUF2512-domain-containing-protein
MSDIALVLIKFISCIIAFAIGLALFFPATLVQIISFSLFVTIVSYVFVDKIILERIGRSAAIMTDFLLTYLSVWIFGNILLDHYMQIAWGSILSALVFTLCEVIVQRFSHAYERHNSDNIHLNRRFSYGTEFAEEQNPLDKNKKK
>CP024098.1|AWC28898.1|2221425_2224956_-|DUF4020-domain-containing-protein
MTFLGKEGIRMWITSEVEIPEELFDHLEQGKLVLFVGAGVSMKGKSNLPNFDDLVDEIAKALYVEKREITEPHDYYLGKIAKTKDVHQIAKDLVNVEGSKPNPLHYAIPRLFPKDTDVRIVTTNFDQHFTTAMRESDRDFNIYYAPALPTGRAFKGLAYIHGNVEQEKENLILTDGDFGRAYLTEGWARRFLVDLFSNYTVLFIGYSHNDPVMKYLATGLPPSTRRYAFVAHGDNTYHWEHLGVKPIVYPNKANNHQALVRAVKRWAELMGDNYITKRMRIRDIVTVPPSVEQEQLSYIKQAIKKIEMLRYFVEFARDYGWVEWLEAEGKLQNLFRMTSHYDEVDELLAAWLVEQFLVSHQKELFQLIFKNHSKISPLLWKSICTYLKETKKPMDPILFAKWTLLLLETAENNSQSIEKISYLLQKCSFPEHKEISVLLLTFILDGKIKLKRVKRWEDDMQDSVELEESSCLPVSVFSHVQRIWEEKMKPHISYFAGPILVMGLEKLQMLSLRQTALQKRDGVLYHTMEFSEHDLQPKDFTFLIRIMKECLAYLCEHNKEKAAYYIAQMIDTDSILQKKIAIEAMSENTFVTADEKLMWLRKQQLIFDFTYKHEVFQFLKKHYQNALEKTKKEVIHEVMKHLENERFFDACLVLDLLYTCDANSTSTARAYRIMKRTHPHFTSNQYGEKKEEVRAPNIICDVTADGLLKLKGHEIKKQILLFSNDDSFEQRHFLEMLSKACKLNVDWSIALAYQLIGEQRVSDEIWFVCIREWRNNRKLTNEQIQKIIPLLQQFVRNPAFYWLISSFLYEISNRLEDFQENQIRVVKRFAFSLFPHIMKGESSFKVGELDFYNESIQHPVGKMTSVLLKLLAYDHLYDRNIHEYLFLFEEQIKVASERTHFMLARLTADVTFLFHIEKQWCRKYVLPYLKLNREHKAVKYAWAGLCYTQINLPLFTEIKKYIKYAAEHLELLHPHTKQVFLKWLSFVCIKCVLYWGQRTDWVYMIFIEEKEHDKIKFLKHLCYYVKTLSAREKQKFWDSWLATFLKERPKMSLITGREYVMLLRFVFYMDEVAEKGVYTILNCFPIPIEHCSEAEMKQLLLTILTRKEKVIAHVQAYAKLFFILLQIVQDASSIENEMIQMKEMLETCHVDDDILTAIQNEMIRIGIVVTNFQQES
>CP024098.1|AWC28897.1|2219581_2220658_-|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase
MANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAERNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQSFIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEFMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS
>CP024098.1|AWC28896.1|2217656_2219282_-|ABC-transporter-ATP-binding-protein
MITVSNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIEPTTGDVHITPGERLAVLKQNHFEYEEFPVLETVIMGHTRLYEVMQEKNAIYMKEDFSDEDGMRAAELEGEFAELNGWEAESEAAILLKGLGIGEELHDKKMSELTGAEKVKVLLAQALFGQPDVLLLDEPTNHLDLKAIQWLENFLMNFENTVIVVSHDRHFLNKVCTHMADLDFGKIQLYVGNYDFWYESSQLALKLTQDANKKKEEKIKELQNFIARFSSNASKAKQATSRKKLLDKITLDDIKPSSRRYPFVGFTPEREVGNDLLTVEGLSKTIDGEKVLDNVYFTLNKGDKVAFIGRNDIAMTTLFKILMGEMEPDSGSFKWGVTTSQSYFPRDNSAYFENSEYNLVEWLRQFSPQDESESFLRGFLGRMLFSGEEVKKNVSVLSGGEKVRCMLSKMMLSGANVLVLDDPTNHLDLESITALNNGLIAFKGTILFTSHDHQFVQTIANRIIEVTPNGVIDKETTYDEYLENEELQKQVSAMYQNK
>CP024098.1|AWC28895.1|2215200_2217174_-|LTA-synthase-family-protein
MKQLLQKSKRVLSNHFGFFIFAVVLFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAILFLGLALFAKGKRSYILLIVINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGEIGGSVLALLQPYDPLYFLDTIVLLVLVLTKVANPKPIRVAKYKLSLVFISAILIFSINLGLAESDRPQLLTRTFDRNYIVKYLGAYNYTIYDGIQSMKASTERAMADGDSMTEVRNYIASNYASPSAEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFINSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQAAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNEKDVVNYGLKDKPFFNESIPLLETVKQPFYTKFITLSNHFPYPIDKEEATIEPATTGDSSVDTYFQTARYLDEAVKGFVDYLKQSGLYDNSIIVMYGDHYGISDNHNRAMSQIMGKEIHSFENAQLQRVPLIVRVPGIKGGVQHQYGGEIDVLPTLLHLLGIDTKDYIQFGTDLLSPEHKQVVAFRNGNYVSPTVTALNGRYYDTTTGEPVEVTEEIKQNEQMVQQTLKLSDQVVNGDLLRFYTPEGFTPVDRSKYNYNHRDKNKTKVKTTQDTKTE
>CP024098.1|AWC28894.1|2212459_2214565_-|PTS-lichenan-transporter-subunit-IIC
MILDYRSAAILQQMMQADSYTSVDQLTEVLQVSKRTIYYDMKKVDDWLITEHLEPIQYVRPLGYCLDKKTKQKVAQKLQGLITVQYEYSPQERKAWLALYLLTEEKRILLEDLIKLIQVSRNTTLADLKKLKAELGKFKLSLQFHRKQGYYIKGMEQGKRNVLIAYLSQLIAKHGWEYVVSHMRNIVNHGEGEKKQTAQDKLHVIKGILSKCEEFLGVQYTDEVLENLSVYMYLFCSRIVKGRYIEMEETEKAVLRETKHFQAATYIGTQFEKLLYIKFPKDEIYYITTHLLGAKVNAQQKEYEKNDVHGIWHIVDCMIQDFQHYACVIFRDFTGLASDLYLHMKPAFYRVKYGIEIKNPLLQIIRNSYAEVYHLTKKVVHHFEQYVGKEISEDEIAFITMHFSAWMRKEGIVPSPRKTALLVCPNGIGTSRMLQYQLEQLFSNIDILQAISKREYESNTFDVDCIITTTELEKGLIPIFMVNPILTDAEKASLFRKVNATLFREDQNDSADIIMQMIHKYADVRDEHALKRELREFISGPVHFGREEKYKPMLNELLTKEYIQLQDHVDSWEGAIRIEAKPLLQTEYISEEYVQEMIANVKKLGPYIVIAPKIAIPHARPESGVKKLGMSLLQLKESVSFSEKQEHAANLIIVLAAIDNETHLKALAQLSDMLSQPENVDLLIRSNSKEQMLEMIAKYSN
>CP024098.1|AWC28893.1|2212177_2212447_-|PTS-lactose-transporter-subunit-IIB
MKKILVVCGNGLGSSFIVEMNVKKILDELGLQAEVSHTDLASSKSEQADLYLGSKDIICNLEDGVRTVAGLTNILDQNEIKEALQKHLM
>CP024098.1|AWC28903.1|2229433_2229697_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDIGEKRVGKACKKLKQYLTWTQNSVFEGELSRTQLLKCLAELDQIIISSEDSIYLYEVNNPRNIKKKVFGIEKSYEELFL
>CP024098.1|AWC28904.1|2230677_2231175_-|CRISPR-associated-protein-Cas4
MKGTYIHYYFVCHRKLWLFVHQIQLEKESERVIEGKILHDSTYQRMEHRELDIDGVGKIDGIEGEYIREIKLTSKMQEADRWQLLYYLAELKKRGVTKKGLLSYKKEKRTEEVHLTEANQQELENIQKRIQAIILSDKPPKLEKKKYCSSCAYYDFCFSGEGEGC
>CP024098.1|AWC28905.1|2231237_2233463_-|CRISPR-associated-helicase/endonuclease-Cas3
MFLAKSNPKETLREHTDELRSRYKKLKESYGHYFDERIWELLLYAVDYHDAGKAHEPFQLNIRRALGEGVKLQRNLEVPHNYLSPFLLPESIFSLPKKDYQALIQAIAYHHERDIEPNDTLIRQALWQDLWPKMDEINKHLNINGANLEKKFNRILAQLHRRIKYSDNKENYVDYVILKGLLHRIDHAASAHVDIEIDAKQDFKKLVDAGFQKIAEKKRVPVEEVYRDLQKHAHKHRKENLIIVAQTGMGKTEAALLWASDSKTFFTLPLRVSINALFHRVYEKMNYKNVGLLHSSSMDYLTENLEEDWEVIAEQSKHFSSKLLFTTIDQILKFPFLYRGYEKELATMAYSSVVIDEIQAYDPKIAAVLVRALEMIYLVGGKFLLMTATLPSIYLETLNESDIISSDGFRVDTFIDDCVIRHCIEVVEKPIVDDFEKIVDLGKQKKILVIANTVKRAMELYNKIKEHSDNVHVFHSMYIQKHRTLIEKELLLFDENKEATGIWITTQLVEASIDIDFDVLFTEAATLDSLCQRFGRCYRRRQYMMPQEPNVFIYAVDMSGVKYVYDEEILMKSLDILRPFNRKILLESQKIELVSQLYSRENLKGTEFLKTFDDALEQLQTFEDYTLSSKDAQKLLRDIQAELVIPRNIYDENEHLFEQLKIVNKEERARLYREIAKLTVSLRKNRVRGKTSRIPHERIQSNGKKYNLLPWIKILELQYDFDEKSKTGTGVLLDQELDNFI
>CP024098.1|AWC28906.1|2233516_2234215_-|type-I-B-CRISPR-associated-protein-Cas5
MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLLQANELLPLRFSIQGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHIAGEEALLERIYQHFIELNQHLSLGRHEDLVRVDEVTFVELEECDEWYSKYAIYVPKYYYKTDFPAGIPYRLNWTYKIVNGIREWNKIPSLYVNGNNPHFEDGKLFHTDGEHIVLWNE
>CP024098.1|AWC28907.1|2234211_2235105_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MNNKALTLTIIFKASSLNYGEGTANISELKKFHRGNGEVYSFASRQAIRYDIVRLGNQLFNWNLNVVDKSKGVVQFKDDCTIADSVEMDLFGYMKTKAKAGADKRSAVVRLSHAVSLEPYRSDLEFLNNMGLASRIQENPNLATLEQHESLYTYTLTVDLSKVGVDGEIELPVDEKVNRVKQLIELTKYLNREIRGRQENLSPLFVIGGVYPIANPFFLGRISLQNFDSNLLNVKSLASVLGQTVLGHDVRTCTKIGLVDGVFANEEEISQLTDTVSVEEFYQHVMNEVEQFYKVLV
>CP024098.1|AWC28908.1|2235097_2236846_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MIFVTEEIPLAAEEWTITQGLVGYYRILKHAGIKVKTTDEGILFNPEHLRNFEHYYFDYFLDRFSVAKRDEQNIRRTFLKFRAESESKGSKEAKRRMQAAKKSLDETIKKTAIEKVEKKFEDSSHKKRLVEYATLIRNQKTYNPEMDKWIEEYIQALSEPNINEKLTLNYFKATVLGTYFGQVSFLNVSHTSKDIEEQKEIFRKDYIESLLADLELQQMIARAEDSDEIMKYLEISTHEMAKKLKTKFKKMTIQQIKDYVSNEINCCSFFDSQWAFEQYSELHFSPLSMSASKALNFYWNANGTLTIPVSKLAKLILFCAPAGASIIGGKSLFVQREGRFEQVIYANETYEIGRSKDKAFDEIIFDLIAEQKTKAQHTGDSYLILEYSSEYNAKKTDLQYLHLTPGLCSFFKEKNCTKWFSRLNYVLRNQIVHAFLRYQDSKHIIHNALRKKLQEQKLANEIVYACLLRCYYLFFVKGEGKMNTDLKTSKNRIWSAFYEGVAIKNIVEEGKIRSVAYRLLNAIRSNDKKMFLDTVMRLYMSVEKPFPRVFMNILDESNIDFASIGDSFIAGLISNEEEKINE
>CP024098.1|AWC28909.1|2236845_2237547_-|CRISPR-associated-endoribonuclease-Cas6
MRLHIKLQTNRFPISYRMMMVSFIKEALKLSDAAYFQQIYQESKANRPFSYGVYIHDYKLNATEFHIKGYVGLTITSPDAQFMLHFYNGLMKMNDFRYKGFSLKRMKVQMVNSADINQNHVYFKTLSPLLIRDKHAKPIFIDDDKFEKELNYISDTVLKEFRGYGLKQPLIFTSKNMKKVVVKEKIHSDHDTLFFTGYHGIFSLQGAVEDLKILSEIGLGFRSSQGFGAVEVV
>CP024098.1|AWC28910.1|2239783_2240110_-|antibiotic-biosynthesis-monooxygenase
MFIETKTLTVKEGTSDLVVQRFSGEGMIEKFEGFIDLNVLVKKVRRGDEEVVIMIRWESEEAWKNWETSEEHLAGHRANRGKPKPEHILNAEHAVYYVKATKSAYQQS
>CP024098.1|AWC28911.1|2240451_2240796_+|hypothetical-protein
MRKAILIFIVAIFIIGIVHIAVTPINYKSYTIEALWFASAGCTLIFLAFLNYVLISIKQRQTRFFVICHTANILCTILVAFILTIAFAPHIILLFVLLVSKTLLVIGFQFSSKS
>CP024098.1|AWC28912.1|2240920_2241250_-|hypothetical-protein
MSFNQVLKVIDENIGKRFVLGIDGLSRLGKTTLVKQLEQKLKQKGASFYIFHIDDHIVERNKRYHTKFEEWYEYYYLQWDIEWLRYHFFQQLKWKEQFRFLGASPKTPS

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Crispr_ID: CP024098_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP024098_4

2238882-2239497

Unclear

I-A

Consensus_repeat	Method
CTTTATATCCCACTACGTTCAGATAAAAC	CRISPRCasFinder
CTTTATATCCCACTACGTTCAGATAAAAC	CRT
CTTTATATCCCACTACGTTCAGATAAAAC	PILER-CR

9 spacers

cas6,cas8b2,cas7,cas5,cas3,cas4,cas2

The CRISPR arrays of CP024098_4

>merge|CP024098|4|2238882-2239497|CRISPRCasFinder,CRT,PILER-CR
TTATCTTATCCACTACGTTCAGATAAAACTTTCTAACAATGTCCAAAAACCATTGAATACATTGGATTTATATCCCACTACGTTCAGATAAAACTGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAACTTTATATCCCACTACGTTCAGATAAAACAGGATTTCACGGAGCGATTGCAAAGAAAAACATCCCCTTTATATCCCACTACGTTCAGATAAAACCACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCCCTTTATATCCCACTACGTTCAGATAAAACCAAATGAAACAAATCATAAAATCGAGGTGAAAACATCTTTATATCCCACTACGTTCAGATAAAACTTGAAGGTGGCTTTGTACTAGAAGGACTCGACGCACTTTATATCCCACTACGTTCAGATAAAACTGTAGCGAACCGTTTTATTTAGAAGAATTAACTCATCTTTATATCCCACTACGTTCAGATAAAACTGAACCATTTTTCAATAATCAATATTCCTTTCTTAAGCTTTATATCCCACTACGTTCAGATAAAACTCAAAGTCCTCGCGCTCTCCTGGAACCAACGGCATACTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|4|4|2238882-2239497|CRISPRCasFinder
TTATCTTATCCACTACGTTCAGATAAAAC	TTTCTAACAATGTCCAAAAACCATTGAATACATTGG
ATTTATATCCCACTACGTTCAGATAAAAC	TGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAA
CTTTATATCCCACTACGTTCAGATAAAAC	AGGATTTCACGGAGCGATTGCAAAGAAAAACATCCC
CTTTATATCCCACTACGTTCAGATAAAAC	CACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCC
CTTTATATCCCACTACGTTCAGATAAAAC	CAAATGAAACAAATCATAAAATCGAGGTGAAAACAT
CTTTATATCCCACTACGTTCAGATAAAAC	TTGAAGGTGGCTTTGTACTAGAAGGACTCGACGCA
CTTTATATCCCACTACGTTCAGATAAAAC	TGTAGCGAACCGTTTTATTTAGAAGAATTAACTCAT
CTTTATATCCCACTACGTTCAGATAAAAC	TGAACCATTTTTCAATAATCAATATTCCTTTCTTAAG
CTTTATATCCCACTACGTTCAGATAAAAC	TCAAAGTCCTCGCGCTCTCCTGGAACCAACGGCATA
CTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|4|3|2238882-2239497|CRT
TTATCTTATCCACTACGTTCAGATAAAAC	TTTCTAACAATGTCCAAAAACCATTGAATACATTGG
ATTTATATCCCACTACGTTCAGATAAAAC	TGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAA
CTTTATATCCCACTACGTTCAGATAAAAC	AGGATTTCACGGAGCGATTGCAAAGAAAAACATCCC
CTTTATATCCCACTACGTTCAGATAAAAC	CACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCC
CTTTATATCCCACTACGTTCAGATAAAAC	CAAATGAAACAAATCATAAAATCGAGGTGAAAACAT
CTTTATATCCCACTACGTTCAGATAAAAC	TTGAAGGTGGCTTTGTACTAGAAGGACTCGACGCA
CTTTATATCCCACTACGTTCAGATAAAAC	TGTAGCGAACCGTTTTATTTAGAAGAATTAACTCAT
CTTTATATCCCACTACGTTCAGATAAAAC	TGAACCATTTTTCAATAATCAATATTCCTTTCTTAAG
CTTTATATCCCACTACGTTCAGATAAAAC	TCAAAGTCCTCGCGCTCTCCTGGAACCAACGGCATA
CTTTATATCCCACTACGTTCAGATAAAAC

>CP024098|4|3|2238948-2239497|PILER-CR
TTTATATCCCACTACGTTCAGATAAAACT	GGGACAAACATGCTACTTTCTTGAACGCTCAGTCAAC
TTTATATCCCACTACGTTCAGATAAAACA	GGATTTCACGGAGCGATTGCAAAGAAAAACATCCCC
TTTATATCCCACTACGTTCAGATAAAACC	ACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCCC
TTTATATCCCACTACGTTCAGATAAAACC	AAATGAAACAAATCATAAAATCGAGGTGAAAACATC
TTTATATCCCACTACGTTCAGATAAAACT	TGAAGGTGGCTTTGTACTAGAAGGACTCGACGCAC
TTTATATCCCACTACGTTCAGATAAAACT	GTAGCGAACCGTTTTATTTAGAAGAATTAACTCATC
TTTATATCCCACTACGTTCAGATAAAACT	GAACCATTTTTCAATAATCAATATTCCTTTCTTAAGC
TTTATATCCCACTACGTTCAGATAAAACT	CAAAGTCCTCGCGCTCTCCTGGAACCAACGGCATAC
TTTATATCCCACTACGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP024098.1\|AWC28911.1\|2240451_2240796_+\|hypothetical-protein	unknown	unknown	unknown
CP024098.1\|AWC28917.1\|2245175_2245640_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240044
CP024098.1\|AWC28904.1\|2230677_2231175_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
CP024098.1\|AWC28918.1\|2245998_2246244_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|365903
CP024098.1\|AWC28913.1\|2241228_2241795_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
CP024098.1\|AWC28908.1\|2235097_2236846_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
CP024098.1\|AWC28910.1\|2239783_2240110_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
CP024098.1\|AWC28901.1\|2227235_2227619_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
CP024098.1\|AWC28919.1\|2246374_2247415_-\|NAD-dependent-dehydratase	unknown	unknown	gnl\|CDD\|187575
CP024098.1\|AWC28900.1\|2225599_2226937_-\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
CP024098.1\|AWC28915.1\|2242647_2243184_-\|DUF2812-domain-containing-protein	unknown	unknown	gnl\|CDD\|378589
CP024098.1\|AWC28906.1\|2233516_2234215_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
CP024098.1\|AWC28909.1\|2236845_2237547_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
CP024098.1\|AWC28905.1\|2231237_2233463_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP024098.1\|AWC28907.1\|2234211_2235105_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP024098.1\|AWC28914.1\|2242164_2242410_+\|DNA-alkylation-repair-protein	unknown	unknown	unknown
CP024098.1\|AWC28903.1\|2229433_2229697_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP024098.1\|AWC28912.1\|2240920_2241250_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|169051
CP024098.1\|AWC28916.1\|2243185_2243509_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|163261
CP024098.1\|AWC28902.1\|2228237_2228492_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376564

Protein	Function_ID	Function_description	E-value
CP024098.1\|AWC28913.1\|2241228_2241795_-\|N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.23367e-45
CP024098.1\|AWC28917.1\|2245175_2245640_-\|NUDIX-domain-containing-protein	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.1182e-48
CP024098.1\|AWC28904.1\|2230677_2231175_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.58631e-58
CP024098.1\|AWC28918.1\|2245998_2246244_-\|hypothetical-protein	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	0.00258085
CP024098.1\|AWC28908.1\|2235097_2236846_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	4.631e-10
CP024098.1\|AWC28910.1\|2239783_2240110_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	5.76195e-19
CP024098.1\|AWC28901.1\|2227235_2227619_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.47212e-43
CP024098.1\|AWC28919.1\|2246374_2247415_-\|NAD-dependent-dehydratase	gnl\|CDD\|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.61475e-84
CP024098.1\|AWC28900.1\|2225599_2226937_-\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
CP024098.1\|AWC28915.1\|2242647_2243184_-\|DUF2812-domain-containing-protein	gnl\|CDD\|378589	pfam11193, DUF2812, Protein of unknown function (DUF2812). This is a bacterial family of uncharacterized proteins, however some members of this family are annotated as membrane proteins.	5.25447e-33
CP024098.1\|AWC28906.1\|2233516_2234215_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.84624e-29
CP024098.1\|AWC28909.1\|2236845_2237547_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.0641e-22
CP024098.1\|AWC28905.1\|2231237_2233463_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.29099e-64
CP024098.1\|AWC28907.1\|2234211_2235105_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	4.74396e-53
CP024098.1\|AWC28903.1\|2229433_2229697_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.02502e-27
CP024098.1\|AWC28912.1\|2240920_2241250_-\|hypothetical-protein	gnl\|CDD\|169051	PRK07667, PRK07667, uridine kinase; Provisional.	4.84898e-47
CP024098.1\|AWC28916.1\|2243185_2243509_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	5.02854e-08
CP024098.1\|AWC28902.1\|2228237_2228492_-\|hypothetical-protein	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	0.000135246

>CP024098.1|AWC28909.1|2236845_2237547_-|CRISPR-associated-endoribonuclease-Cas6
MRLHIKLQTNRFPISYRMMMVSFIKEALKLSDAAYFQQIYQESKANRPFSYGVYIHDYKLNATEFHIKGYVGLTITSPDAQFMLHFYNGLMKMNDFRYKGFSLKRMKVQMVNSADINQNHVYFKTLSPLLIRDKHAKPIFIDDDKFEKELNYISDTVLKEFRGYGLKQPLIFTSKNMKKVVVKEKIHSDHDTLFFTGYHGIFSLQGAVEDLKILSEIGLGFRSSQGFGAVEVV
>CP024098.1|AWC28908.1|2235097_2236846_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MIFVTEEIPLAAEEWTITQGLVGYYRILKHAGIKVKTTDEGILFNPEHLRNFEHYYFDYFLDRFSVAKRDEQNIRRTFLKFRAESESKGSKEAKRRMQAAKKSLDETIKKTAIEKVEKKFEDSSHKKRLVEYATLIRNQKTYNPEMDKWIEEYIQALSEPNINEKLTLNYFKATVLGTYFGQVSFLNVSHTSKDIEEQKEIFRKDYIESLLADLELQQMIARAEDSDEIMKYLEISTHEMAKKLKTKFKKMTIQQIKDYVSNEINCCSFFDSQWAFEQYSELHFSPLSMSASKALNFYWNANGTLTIPVSKLAKLILFCAPAGASIIGGKSLFVQREGRFEQVIYANETYEIGRSKDKAFDEIIFDLIAEQKTKAQHTGDSYLILEYSSEYNAKKTDLQYLHLTPGLCSFFKEKNCTKWFSRLNYVLRNQIVHAFLRYQDSKHIIHNALRKKLQEQKLANEIVYACLLRCYYLFFVKGEGKMNTDLKTSKNRIWSAFYEGVAIKNIVEEGKIRSVAYRLLNAIRSNDKKMFLDTVMRLYMSVEKPFPRVFMNILDESNIDFASIGDSFIAGLISNEEEKINE
>CP024098.1|AWC28907.1|2234211_2235105_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MNNKALTLTIIFKASSLNYGEGTANISELKKFHRGNGEVYSFASRQAIRYDIVRLGNQLFNWNLNVVDKSKGVVQFKDDCTIADSVEMDLFGYMKTKAKAGADKRSAVVRLSHAVSLEPYRSDLEFLNNMGLASRIQENPNLATLEQHESLYTYTLTVDLSKVGVDGEIELPVDEKVNRVKQLIELTKYLNREIRGRQENLSPLFVIGGVYPIANPFFLGRISLQNFDSNLLNVKSLASVLGQTVLGHDVRTCTKIGLVDGVFANEEEISQLTDTVSVEEFYQHVMNEVEQFYKVLV
>CP024098.1|AWC28906.1|2233516_2234215_-|type-I-B-CRISPR-associated-protein-Cas5
MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLLQANELLPLRFSIQGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHIAGEEALLERIYQHFIELNQHLSLGRHEDLVRVDEVTFVELEECDEWYSKYAIYVPKYYYKTDFPAGIPYRLNWTYKIVNGIREWNKIPSLYVNGNNPHFEDGKLFHTDGEHIVLWNE
>CP024098.1|AWC28905.1|2231237_2233463_-|CRISPR-associated-helicase/endonuclease-Cas3
MFLAKSNPKETLREHTDELRSRYKKLKESYGHYFDERIWELLLYAVDYHDAGKAHEPFQLNIRRALGEGVKLQRNLEVPHNYLSPFLLPESIFSLPKKDYQALIQAIAYHHERDIEPNDTLIRQALWQDLWPKMDEINKHLNINGANLEKKFNRILAQLHRRIKYSDNKENYVDYVILKGLLHRIDHAASAHVDIEIDAKQDFKKLVDAGFQKIAEKKRVPVEEVYRDLQKHAHKHRKENLIIVAQTGMGKTEAALLWASDSKTFFTLPLRVSINALFHRVYEKMNYKNVGLLHSSSMDYLTENLEEDWEVIAEQSKHFSSKLLFTTIDQILKFPFLYRGYEKELATMAYSSVVIDEIQAYDPKIAAVLVRALEMIYLVGGKFLLMTATLPSIYLETLNESDIISSDGFRVDTFIDDCVIRHCIEVVEKPIVDDFEKIVDLGKQKKILVIANTVKRAMELYNKIKEHSDNVHVFHSMYIQKHRTLIEKELLLFDENKEATGIWITTQLVEASIDIDFDVLFTEAATLDSLCQRFGRCYRRRQYMMPQEPNVFIYAVDMSGVKYVYDEEILMKSLDILRPFNRKILLESQKIELVSQLYSRENLKGTEFLKTFDDALEQLQTFEDYTLSSKDAQKLLRDIQAELVIPRNIYDENEHLFEQLKIVNKEERARLYREIAKLTVSLRKNRVRGKTSRIPHERIQSNGKKYNLLPWIKILELQYDFDEKSKTGTGVLLDQELDNFI
>CP024098.1|AWC28904.1|2230677_2231175_-|CRISPR-associated-protein-Cas4
MKGTYIHYYFVCHRKLWLFVHQIQLEKESERVIEGKILHDSTYQRMEHRELDIDGVGKIDGIEGEYIREIKLTSKMQEADRWQLLYYLAELKKRGVTKKGLLSYKKEKRTEEVHLTEANQQELENIQKRIQAIILSDKPPKLEKKKYCSSCAYYDFCFSGEGEGC
>CP024098.1|AWC28903.1|2229433_2229697_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDIGEKRVGKACKKLKQYLTWTQNSVFEGELSRTQLLKCLAELDQIIISSEDSIYLYEVNNPRNIKKKVFGIEKSYEELFL
>CP024098.1|AWC28902.1|2228237_2228492_-|hypothetical-protein
MKDTTKYVGLDVSKEKIAVAIADEGREEPRYLGMIPHTPESLRKLIKKLGAVEHLKACYKAGSTGYGIYRLLFSLGVDCAVIAP
>CP024098.1|AWC28901.1|2227235_2227619_-|VOC-family-protein
MMIHKVGQIMLYVKDQDEAVQFWTEKMGFHLIAEEDNGKGFRWIEIAPTKEAETSIVLHNKEFIAKMQPELNLNTPSMLFFTENIEQLHKQLVDKKVAVGEIVNMPTGKAFNFADDEGNYFAIMEKS
>CP024098.1|AWC28900.1|2225599_2226937_-|D-serine-ammonia-lyase
MWEKMIKGKTIRKWTEENPILQQLIETSEVFWENPNYSSYEKARQDFVLTTEDVKEAEARLLRFAPYIAKVFPETKEMDGIIESPLVETMHMKQYLEDAFAQEMPGRFLLKCDNNLPISGSIKARGGIYEVLQHAEKLAIEHNLLCEEDHYAKLDSDRFREFFSQYSIAVGSTGNLGLSIGIMSAKLGFQVTVHMSADAKEWKKELLRNKGVTVVEYESDYSKAVEEGRKQAEQDPHCYFIDDENSKHLFLGYAVAASRVKQQLEDKNIRVDKDHPLFVYLPCGVGGGPGGVAFGLKLLFGDAVHCFFAEPTHSPCMLLGLVTGLHDEIAVQDFEIDNVTEADGLAVGRASGFVGKIMEPLLSGCYTVEDQQLYELLKAMVDTENIRLEPSALAAVYGSVQLYRQENYVKKHKLEGKMNRSTHMMWATGGGMVPKSVFDEYYQNQ
>CP024098.1|AWC28910.1|2239783_2240110_-|antibiotic-biosynthesis-monooxygenase
MFIETKTLTVKEGTSDLVVQRFSGEGMIEKFEGFIDLNVLVKKVRRGDEEVVIMIRWESEEAWKNWETSEEHLAGHRANRGKPKPEHILNAEHAVYYVKATKSAYQQS
>CP024098.1|AWC28911.1|2240451_2240796_+|hypothetical-protein
MRKAILIFIVAIFIIGIVHIAVTPINYKSYTIEALWFASAGCTLIFLAFLNYVLISIKQRQTRFFVICHTANILCTILVAFILTIAFAPHIILLFVLLVSKTLLVIGFQFSSKS
>CP024098.1|AWC28912.1|2240920_2241250_-|hypothetical-protein
MSFNQVLKVIDENIGKRFVLGIDGLSRLGKTTLVKQLEQKLKQKGASFYIFHIDDHIVERNKRYHTKFEEWYEYYYLQWDIEWLRYHFFQQLKWKEQFRFLGASPKTPS
>CP024098.1|AWC28913.1|2241228_2241795_-|N-acetyltransferase
MGFPTLETERFILRELTLLDAENMFHYFQKESVMRYFGMDAIRNMEQVKRMIQMFSKKYKEGSQVRWGIELKGTNRFIGTCGFHFINLNHKRAEIGYELDDAYWGKGYATEAVQTIVTYAFQTMKLIRIGAVVYKENEASHKLLKKIGFQKEGLLRKYMIQNNVEYDTIIYSLLAEDWEKRSCLSIKY
>CP024098.1|AWC28914.1|2242164_2242410_+|DNA-alkylation-repair-protein
MEPMLCPNCKTNRTRFNILEQQVKPVKLNPQTGQIEEEYTNETLNVFHMSYQGPTYRVQCAVCGLVENPEQFIKPAQNKLF
>CP024098.1|AWC28915.1|2242647_2243184_-|DUF2812-domain-containing-protein
MEIKKTFKFFTAWNLEKEEAYLREMHQKGWAFQKYHFMYTFKKTEPKDVVYKADFNFDFQKSLKNQREYLEIYEMSGWKYVSSFTKWHYFCKEVVDKNELPDIYSETETRIEKLKDLLNHLVIIFLSILPAISISCLESPANKLSIIIKGFIGFVVCIHMYMFVRLILKIRKLKKEII
>CP024098.1|AWC28916.1|2243185_2243509_-|PadR-family-transcriptional-regulator
MDEKAKKYIPLTEATYYILLSFAKRIHGYGVMQMVEEMTDGEVKLGPGTLYGNITKLLTEKLIVEVDSTDRKKCYMLTPFGREVLELEFKRLQRSVQNGKQILREKM
>CP024098.1|AWC28917.1|2245175_2245640_-|NUDIX-domain-containing-protein
MDLTFQVNQSCFNYRVGAICKHDNKILMLQNEGEDFWYVPGGRVQLLETSEVAIKRELKEELGVDVAVKRPLWIVENFFTYDSRQFHEISLYYEVNLLTLPVKGADSFLFEEEGRKYKFQWIPLEQICEYNVKPEFLKDKMTQLPLHVEHIVKN
>CP024098.1|AWC28918.1|2245998_2246244_-|hypothetical-protein
MKGIFWLNLYMSLHVRMGETLYYGLGVRITNSHSEEKVIRHSGLTPNSHAKMFFIPKTDWGGVILTNKNHIFEEEALPQLK
>CP024098.1|AWC28919.1|2246374_2247415_-|NAD-dependent-dehydratase
MKVLILGGTRFLGRALVEEALKRGHEVTLFNRGTNKEIFPKVEQLIGDRDGDVSALKNRNWDIVMDTYGFAPHQIRNIATILGGNIEHYTFISSMSTYKDWIPLHIKEDYQLQSIPPREKLKAIEDGEASPYEYYGGLKVLCEKEAEKYWPGRVLHMRAGLLVGAFDYTDRLPYWIQRVAQGGEVLVPEHSNRPVQLIDVKDVATWAFNMAEGRKVGTFNVTGPNNELTIGELLNTCKAVTNSDAEFVWVEEQFLLENKVQPWTEMPLWIPETFPLEGETEPWKGSFFISIEKAVNTGLSFRPIQNTISDVYQWEKSRKDTERKAGMAREKERELLKLWFQQEKMR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP024098_3	3.6\|2229080\|37\|CP024098\|CRISPRCasFinder,CRT,PILER-CR	2229080-2229116	37	CP024098.1	811928-811964	0	1.0

1. spacer 3.6|2229080|37|CP024098|CRISPRCasFinder,CRT,PILER-CR matches to position: 811928-811964, mismatch: 0, identity: 1.0

tcttttaaaagctgtagtatttgtttttcgtattcga	CRISPR spacer
tcttttaaaagctgtagtatttgtttttcgtattcga	Protospacer
*************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_AP014870	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK6	12518-12546	0	1.0
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP010096	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence	5323-5351	0	1.0
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP004882	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence	5325-5353	1	0.966
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP011355	Bacillus thuringiensis strain YC-10 plasmid pYC10, complete sequence	2221-2249	1	0.966
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NC_006945	Bacillus phage GIL16c, complete genome	5316-5344	1	0.966
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	AY701338	Bacillus thuringiensis phage GIL16c, complete genome	5316-5344	1	0.966
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP004882	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence	11352-11381	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP011355	Bacillus thuringiensis strain YC-10 plasmid pYC10, complete sequence	8248-8277	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_AP014870	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK6	6774-6803	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NC_006945	Bacillus phage GIL16c, complete genome	11343-11372	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	AY701338	Bacillus thuringiensis phage GIL16c, complete genome	11343-11372	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP053974	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence	1714-1743	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP009346	Bacillus thuringiensis HD1002 plasmid 5, complete sequence	3490-3519	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP045027	Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence	3488-3517	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NC_005258	Bacillus phage Bam35c, complete genome	11417-11446	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	AY257527	Bacillus thuringiensis bacteriophage Bam35c, complete genome	11417-11446	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	AJ536073	Bacillus phage pGIL01, complete genome	11415-11444	1	0.967
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	CP013282	Bacillus phage pGIL02, complete sequence	3490-3519	1	0.967
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	EU408779	Bacillus phage AP50, complete genome	2485-2514	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP004882	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence	2435-2464	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP053974	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence	10677-10706	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP009346	Bacillus thuringiensis HD1002 plasmid 5, complete sequence	12464-12493	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP010096	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence	2433-2462	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP045027	Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence	12462-12491	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NC_005258	Bacillus phage Bam35c, complete genome	2443-2472	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	AY257527	Bacillus thuringiensis bacteriophage Bam35c, complete genome	2443-2472	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	AJ536073	Bacillus phage pGIL01, complete genome	2441-2470	2	0.933
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	CP013282	Bacillus phage pGIL02, complete sequence	12464-12493	2	0.933
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP053974	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence	7661-7689	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP009346	Bacillus thuringiensis HD1002 plasmid 5, complete sequence	9437-9465	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NZ_CP045027	Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence	9435-9463	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	CP013282	Bacillus phage pGIL02, complete sequence	9437-9465	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NC_005258	Bacillus phage Bam35c, complete genome	5471-5499	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	KC152966	Bacillus phage Emet putative gene regulator and hypothetical proteins genes, complete cds	1009-1037	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	KC152967	Bacillus phage Sole hypothetical protein, putative gene regulators, and hypothetical protein genes, complete cds	1045-1073	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	AY257527	Bacillus thuringiensis bacteriophage Bam35c, complete genome	5471-5499	2	0.931
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	AJ536073	Bacillus phage pGIL01, complete genome	5469-5497	2	0.931
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NC_048762	Bacillus phage vB_BtS_B83, complete genome	26059-26088	3	0.9
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NZ_CP020004	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed2, complete sequence	17949-17978	3	0.9
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NZ_CP034552	Bacillus cereus ATCC 14579 plasmid unnamed, complete sequence	2356-2385	3	0.9
CP024098_2	2.8\|2100777\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100777-2100806	30	NC_004721	Bacillus cereus ATCC 14579 plasmid pBClin15, complete sequence	2418-2447	3	0.9
CP024098_2	2.11\|2100974\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100974-2101003	30	NZ_CP010096	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence	11430-11459	3	0.9
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	GU071094	Synechococcus phage S-SM1, complete genome	54124-54153	4	0.867
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NZ_CP014285	Bacillus thuringiensis strain Bt185 plasmid pBT1850055, complete sequence	27260-27289	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NC_004821	Bacillus prophage phBC6A52, complete genome	37850-37879	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NC_049968	Bacillus phage DK2, complete genome	22476-22505	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	KX190832	Bacillus phage vB_BtS_BMBtp13, complete genome	23253-23282	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	MK284528	Bacillus phage DK3, complete genome	23164-23193	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NZ_CP032612	Bacillus thuringiensis strain QZL38 plasmid p.4, complete sequence	34550-34579	5	0.833
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	NC_018502	Bacillus thuringiensis HD-771 plasmid p05, complete sequence	5059-5088	5	0.833
CP024098_4	4.2\|2238976\|37\|CP024098\|CRISPRCasFinder,CRT	2238976-2239012	37	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	248075-248111	5	0.865
CP024098_4	4.10\|2238977\|37\|CP024098\|PILER-CR	2238977-2239013	37	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	248075-248111	5	0.865
CP024098_2	2.2\|2100382\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100382-2100411	30	GU233956	Bacillus phage 11143, partial sequence	20685-20714	6	0.8
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	NC_011738	Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence	213020-213049	6	0.8
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	NC_007051	Staphylococcus phage 2638A, complete genome	13284-13313	6	0.8
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	AY954954	Bacteriophage 2638A, complete genome	13284-13313	6	0.8
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	NZ_CP034567	Vibrio parahaemolyticus strain D3112 plasmid p1, complete sequence	45690-45719	6	0.8
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	675072-675101	6	0.8
CP024098_2	2.9\|2100843\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100843-2100871	29	NC_022088	Bacillus phage Troll, complete genome	4906-4934	6	0.793
CP024098_2	2.10\|2100908\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100908-2100937	30	NZ_CP053575	Citrobacter sp. TSA-1 plasmid unnamed2, complete sequence	7553-7582	6	0.8
CP024098_2	2.10\|2100908\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100908-2100937	30	MG945606	UNVERIFIED: Microviridae sp. isolate 4483-1602, complete genome	1967-1996	6	0.8
CP024098_2	2.1\|2100316\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100316-2100345	30	MN856040	Bacteriophage sp. isolate 317, complete genome	2411-2440	8	0.733
CP024098_2	2.3\|2100448\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100448-2100476	29	NZ_CP050068	Klebsiella aerogenes strain 035 plasmid p35, complete sequence	377728-377756	8	0.724
CP024098_2	2.3\|2100448\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100448-2100476	29	NZ_CP020848	Klebsiella variicola strain KPN1481 plasmid pKPN1481-1, complete sequence	153139-153167	8	0.724
CP024098_2	2.3\|2100448\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100448-2100476	29	NZ_CP043927	Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence	113729-113757	8	0.724
CP024098_2	2.3\|2100448\|29\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100448-2100476	29	NZ_CP021699	Klebsiella pneumoniae strain AR_0158 plasmid tig00000727, complete sequence	347755-347783	8	0.724
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	KX827371	Staphylococcus phage SpT99F3, complete genome	30241-30270	8	0.733
CP024098_2	2.4\|2100513\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100513-2100542	30	MK075002	Staphylococcus phage phiSP38-1, complete genome	32276-32305	8	0.733
CP024098_2	2.5\|2100579\|30\|CP024098\|PILER-CR,CRISPRCasFinder,CRT	2100579-2100608	30	MN047793	Xanthomonas phage Xoo-sp13, complete genome	181943-181972	8	0.733
CP024098_4	4.8\|2239367\|37\|CP024098\|CRISPRCasFinder,CRT	2239367-2239403	37	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	92131-92167	8	0.784
CP024098_4	4.16\|2239368\|37\|CP024098\|PILER-CR	2239368-2239404	37	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	92131-92167	8	0.784
CP024098_4	4.7\|2239302\|36\|CP024098\|CRISPRCasFinder,CRT	2239302-2239337	36	NZ_CP020750	Bacillus mycoides strain Gnyt1 plasmid unnamed7, complete sequence	37822-37857	9	0.75
CP024098_4	4.15\|2239303\|36\|CP024098\|PILER-CR	2239303-2239338	36	NZ_CP020750	Bacillus mycoides strain Gnyt1 plasmid unnamed7, complete sequence	37822-37857	9	0.75
CP024098_3	3.1\|2228752\|37\|CP024098\|CRISPRCasFinder,CRT	2228752-2228788	37	LC168164	Tenacibaculum phage pT24 DNA, complete genome	180412-180448	11	0.703

1. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014870 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK6) position: , mismatch: 0, identity: 1.0

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggtttcggtgg	Protospacer
*****************************

2. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010096 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggtttcggtgg	Protospacer
*****************************

3. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004882 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence) position: , mismatch: 1, identity: 0.966

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggcttcggtgg	Protospacer
********************.********

4. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011355 (Bacillus thuringiensis strain YC-10 plasmid pYC10, complete sequence) position: , mismatch: 1, identity: 0.966

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggcttcggtgg	Protospacer
********************.********

5. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_006945 (Bacillus phage GIL16c, complete genome) position: , mismatch: 1, identity: 0.966

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggcttcggtgg	Protospacer
********************.********

6. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY701338 (Bacillus thuringiensis phage GIL16c, complete genome) position: , mismatch: 1, identity: 0.966

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctctacttttggcttcggtgg	Protospacer
********************.********

7. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004882 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgacgggacgccatacaccgg	Protospacer
.*****************************

8. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011355 (Bacillus thuringiensis strain YC-10 plasmid pYC10, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgacgggacgccatacaccgg	Protospacer
.*****************************

9. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014870 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK6) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgacgggacgccatacaccgg	Protospacer
.*****************************

10. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_006945 (Bacillus phage GIL16c, complete genome) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgacgggacgccatacaccgg	Protospacer
.*****************************

11. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY701338 (Bacillus thuringiensis phage GIL16c, complete genome) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgacgggacgccatacaccgg	Protospacer
.*****************************

12. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053974 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

13. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009346 (Bacillus thuringiensis HD1002 plasmid 5, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

14. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045027 (Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

15. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_005258 (Bacillus phage Bam35c, complete genome) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

16. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY257527 (Bacillus thuringiensis bacteriophage Bam35c, complete genome) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

17. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AJ536073 (Bacillus phage pGIL01, complete genome) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

18. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to CP013282 (Bacillus phage pGIL02, complete sequence) position: , mismatch: 1, identity: 0.967

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
taagtacgacgacgggacgccatacaccgg	Protospacer
******.***********************

19. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to EU408779 (Bacillus phage AP50, complete genome) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatctaaggctatcatgtagtatc	Protospacer
*************.***************

20. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004882 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMBLin15, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

21. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053974 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

22. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009346 (Bacillus thuringiensis HD1002 plasmid 5, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

23. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010096 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

24. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045027 (Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

25. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_005258 (Bacillus phage Bam35c, complete genome) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

26. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY257527 (Bacillus thuringiensis bacteriophage Bam35c, complete genome) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

27. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AJ536073 (Bacillus phage pGIL01, complete genome) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

28. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to CP013282 (Bacillus phage pGIL02, complete sequence) position: , mismatch: 2, identity: 0.933

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatcggaagctatcatgtagtata	Protospacer
********** .******************

29. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053974 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed5, complete sequence) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

30. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009346 (Bacillus thuringiensis HD1002 plasmid 5, complete sequence) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

31. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045027 (Bacillus thuringiensis strain JW-1 plasmid p5, complete sequence) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

32. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to CP013282 (Bacillus phage pGIL02, complete sequence) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

33. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_005258 (Bacillus phage Bam35c, complete genome) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

34. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to KC152966 (Bacillus phage Emet putative gene regulator and hypothetical proteins genes, complete cds) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcgtcttcctccactttcggtttcggtgg	Protospacer
***********.*****.***********

35. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to KC152967 (Bacillus phage Sole hypothetical protein, putative gene regulators, and hypothetical protein genes, complete cds) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

36. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY257527 (Bacillus thuringiensis bacteriophage Bam35c, complete genome) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

37. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AJ536073 (Bacillus phage pGIL01, complete genome) position: , mismatch: 2, identity: 0.931

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
tcctcttcctcgacttttggtttcggtgg	Protospacer
** ******** *****************

38. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_048762 (Bacillus phage vB_BtS_B83, complete genome) position: , mismatch: 3, identity: 0.9

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
tattttgggtagctgatgtagaagtaaaaa	Protospacer
*.******** **.****************

39. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020004 (Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.9

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
tattttgggtagctgatgtagaagtaaaaa	Protospacer
*.******** **.****************

40. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034552 (Bacillus cereus ATCC 14579 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.9

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatctaaggctgtcatgtagtatc	Protospacer
*************.***.***********

41. spacer 2.8|2100777|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_004721 (Bacillus cereus ATCC 14579 plasmid pBClin15, complete sequence) position: , mismatch: 3, identity: 0.9

ggtagcaatctaaagctatcatgtagtata	CRISPR spacer
ggtagcaatctaaggctgtcatgtagtatc	Protospacer
*************.***.***********

42. spacer 2.11|2100974|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010096 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMBLin15, complete sequence) position: , mismatch: 3, identity: 0.9

taagtatgacgacgggacgccatacaccgg	CRISPR spacer
caagtatgacgatggaacgccatacaccgg	Protospacer
.***********.**.**************

43. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to GU071094 (Synechococcus phage S-SM1, complete genome) position: , mismatch: 4, identity: 0.867

-agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
tagtgcta-caatcaaaaaaggtgctattgc	Protospacer
 ***** * **************** ****

44. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014285 (Bacillus thuringiensis strain Bt185 plasmid pBT1850055, complete sequence) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtctgggttgctgatgtagaagtaaaaa	Protospacer
.. *.********.****************

45. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_004821 (Bacillus prophage phBC6A52, complete genome) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtctgggttgctgatgtagaagtaaaaa	Protospacer
.. *.********.****************

46. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_049968 (Bacillus phage DK2, complete genome) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtttgggttgctgatgttgaagtaaaaa	Protospacer
.. **********.***** **********

47. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to KX190832 (Bacillus phage vB_BtS_BMBtp13, complete genome) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtctgggttgctgatgtagaagtaaaaa	Protospacer
.. *.********.****************

48. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to MK284528 (Bacillus phage DK3, complete genome) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtttgggttgctgatgttgaagtaaaaa	Protospacer
.. **********.***** **********

49. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032612 (Bacillus thuringiensis strain QZL38 plasmid p.4, complete sequence) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtctgggttgctgatgtagaagtaaaaa	Protospacer
.. *.********.****************

50. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_018502 (Bacillus thuringiensis HD-771 plasmid p05, complete sequence) position: , mismatch: 5, identity: 0.833

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cggtatgggttgctgatgtagaagtgaaaa	Protospacer
.* * ********.***********.****

51. spacer 4.2|2238976|37|CP024098|CRISPRCasFinder,CRT matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 5, identity: 0.865

tgggacaaacatgctactttcttgaacgctcagtcaa-	CRISPR spacer
tgggacaaacatgctacttttttaaa-gcccaatcaag	Protospacer
********************.**.** **.**.****

52. spacer 4.10|2238977|37|CP024098|PILER-CR matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 5, identity: 0.865

tgggacaaacatgctactttcttgaacgctcagtcaa-	CRISPR spacer
tgggacaaacatgctacttttttaaa-gcccaatcaag	Protospacer
********************.**.** **.**.****

53. spacer 2.2|2100382|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to GU233956 (Bacillus phage 11143, partial sequence) position: , mismatch: 6, identity: 0.8

tgttttgggttgccgatgtagaagtaaaaa	CRISPR spacer
cagtctgggtggctgatgtagaagtaaaaa	Protospacer
.. *.***** **.****************

54. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_011738 (Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence) position: , mismatch: 6, identity: 0.8

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
ataacaagctatcaaaaaaggtgctattgt	Protospacer
*  .***** ************** ****

55. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_007051 (Staphylococcus phage 2638A, complete genome) position: , mismatch: 6, identity: 0.8

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
atttgcaaaaatcaaaaaaggtgcaattga	Protospacer
* *   *. *********************

56. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to AY954954 (Bacteriophage 2638A, complete genome) position: , mismatch: 6, identity: 0.8

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
atttgcaaaaatcaaaaaaggtgcaattga	Protospacer
* *   *. *********************

57. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034567 (Vibrio parahaemolyticus strain D3112 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
cgtgcaagcaatgaaacaaggtgcatatca	Protospacer
 *********** *** ********  * *

58. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
agggcaagcaatcaaaaaagctgtagggga	Protospacer
** ***************** **.*.  **

59. spacer 2.9|2100843|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NC_022088 (Bacillus phage Troll, complete genome) position: , mismatch: 6, identity: 0.793

tcgtcttcctctacttttggtttcggtgg	CRISPR spacer
ttttgttcttctacttttggttccggtgt	Protospacer
*. * ***.*************.*****

60. spacer 2.10|2100908|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053575 (Citrobacter sp. TSA-1 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tttaatgatgttgataagttgccccgcata	CRISPR spacer
atgagtgatattgataagttgtcccgcaaa	Protospacer
 * *.****.***********.****** *

61. spacer 2.10|2100908|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to MG945606 (UNVERIFIED: Microviridae sp. isolate 4483-1602, complete genome) position: , mismatch: 6, identity: 0.8

tttaatgatgttgataagttgccccgcata	CRISPR spacer
tttgatgatgttgataatttgcctcagatt	Protospacer
***.************* *****.*. **

62. spacer 2.1|2100316|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to MN856040 (Bacteriophage sp. isolate 317, complete genome) position: , mismatch: 8, identity: 0.733

ttcgatgtttatccatccactcttcgacaa	CRISPR spacer
ctcgatgtttttccatccactcagcagctg	Protospacer
.********* ***********  *..* .

63. spacer 2.3|2100448|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050068 (Klebsiella aerogenes strain 035 plasmid p35, complete sequence) position: , mismatch: 8, identity: 0.724

tacaaaaagtgactgagggggcttataac	CRISPR spacer
ccgggaaagtgattgagggggcttatgaa	Protospacer
.  ..*******.*************.*

64. spacer 2.3|2100448|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020848 (Klebsiella variicola strain KPN1481 plasmid pKPN1481-1, complete sequence) position: , mismatch: 8, identity: 0.724

tacaaaaagtgactgagggggcttataac	CRISPR spacer
ccgggaaagtgattgagggggcttatgaa	Protospacer
.  ..*******.*************.*

65. spacer 2.3|2100448|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043927 (Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence) position: , mismatch: 8, identity: 0.724

tacaaaaagtgactgagggggcttataac	CRISPR spacer
ccgggaaagtgattgagggggcttatgaa	Protospacer
.  ..*******.*************.*

66. spacer 2.3|2100448|29|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021699 (Klebsiella pneumoniae strain AR_0158 plasmid tig00000727, complete sequence) position: , mismatch: 8, identity: 0.724

tacaaaaagtgactgagggggcttataac	CRISPR spacer
ccgggaaagtgattgagggggcttatgaa	Protospacer
.  ..*******.*************.*

67. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to KX827371 (Staphylococcus phage SpT99F3, complete genome) position: , mismatch: 8, identity: 0.733

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
tttcaacaaaattaaaaaaggtgcaattga	Protospacer
  *  * . ***.*****************

68. spacer 2.4|2100513|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to MK075002 (Staphylococcus phage phiSP38-1, complete genome) position: , mismatch: 8, identity: 0.733

agtgcaagcaatcaaaaaaggtgcaattga	CRISPR spacer
tttcaacaaaattaaaaaaggtgcaattga	Protospacer
  *  * . ***.*****************

69. spacer 2.5|2100579|30|CP024098|PILER-CR,CRISPRCasFinder,CRT matches to MN047793 (Xanthomonas phage Xoo-sp13, complete genome) position: , mismatch: 8, identity: 0.733

tgaaaatttcggtaatgtaaaggtgtttag	CRISPR spacer
cgaagatttcggtaatgtaaagacccgtac	Protospacer
.***.*****************.. . **

70. spacer 4.8|2239367|37|CP024098|CRISPRCasFinder,CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.784

tgaacc---atttttcaataatcaatattcctttcttaag	CRISPR spacer
---actttaatttttcaaaaattaatattcctttcttatt	Protospacer
   **.   ********* ***.***************

71. spacer 4.16|2239368|37|CP024098|PILER-CR matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.784

tgaacc---atttttcaataatcaatattcctttcttaag	CRISPR spacer
---actttaatttttcaaaaattaatattcctttcttatt	Protospacer
   **.   ********* ***.***************

72. spacer 4.7|2239302|36|CP024098|CRISPRCasFinder,CRT matches to NZ_CP020750 (Bacillus mycoides strain Gnyt1 plasmid unnamed7, complete sequence) position: , mismatch: 9, identity: 0.75

tgtagcgaaccgttttatttagaagaattaactcat	CRISPR spacer
tgcagtgaaccgttttatttagaagagcttgctgca	Protospacer
**.**.********************..* .**

73. spacer 4.15|2239303|36|CP024098|PILER-CR matches to NZ_CP020750 (Bacillus mycoides strain Gnyt1 plasmid unnamed7, complete sequence) position: , mismatch: 9, identity: 0.75

tgtagcgaaccgttttatttagaagaattaactcat	CRISPR spacer
tgcagtgaaccgttttatttagaagagcttgctgca	Protospacer
**.**.********************..* .**

74. spacer 3.1|2228752|37|CP024098|CRISPRCasFinder,CRT matches to LC168164 (Tenacibaculum phage pT24 DNA, complete genome) position: , mismatch: 11, identity: 0.703

----catcaaaatcaaaaacagttaaattagatgcagatga	CRISPR spacer
gtgttacagaaac----aacagttgaattagatgcagatgg	Protospacer
    .*. .***.    *******.***************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

157123 : 210989

Bacillus_phage(26.67%)

transposase,integrase,protease

attL 156916:156964|attR 174084:174132

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
156916:156964	attL	NA	NA	NA	NA
AWC27132.1\|157123_158050_+\|integrase	integrase	A0A2I6UG75	Salinibacter_virus	5.5e-11	24.5
AWC30758.1\|158355_159081_+	helix-turn-helix domain-containing protein	A0A1I9S595	Bacillus_phage	2.0e-08	28.6
AWC27133.1\|159573_159948_-	hypothetical protein	NA	NA	NA	NA
AWC27134.1\|161941_162556_+	hypothetical protein	NA	NA	NA	NA
AWC27135.1\|162561_162792_+	hypothetical protein	NA	NA	NA	NA
AWC27136.1\|162805_163042_+	hypothetical protein	NA	NA	NA	NA
AWC27137.1\|163071_163752_+	hypothetical protein	NA	NA	NA	NA
AWC27138.1\|163990_164815_+	hypothetical protein	NA	NA	NA	NA
AWC27139.1\|164829_165249_+	hypothetical protein	NA	NA	NA	NA
AWC27140.1\|165271_165481_+	hypothetical protein	NA	NA	NA	NA
AWC27141.1\|165501_165906_+	hypothetical protein	NA	NA	NA	NA
AWC27142.1\|166140_166791_+	hypothetical protein	M1HN75	Bacillus_virus	2.1e-17	34.6
AWC27143.1\|166898_167321_+	hypothetical protein	A0A2P1JUJ6	Bacillus_phage	1.0e-33	58.6
AWC27144.1\|167407_169594_+	hypothetical protein	A0A2P1JUK2	Bacillus_phage	2.0e-11	41.2
AWC27145.1\|169731_170016_+	hypothetical protein	NA	NA	NA	NA
AWC27146.1\|170032_170341_+	hypothetical protein	NA	NA	NA	NA
AWC27147.1\|170491_171343_+	DNA methyltransferase	A0A1S5PRR3	Streptococcus_phage	6.7e-80	52.3
AWC27148.1\|171326_172607_+	translation elongation factor	NA	NA	NA	NA
AWC27149.1\|172860_173184_+	hypothetical protein	NA	NA	NA	NA
AWC27150.1\|173246_173444_+	hypothetical protein	NA	NA	NA	NA
AWC27151.1\|173647_173863_+	hypothetical protein	NA	NA	NA	NA
AWC27152.1\|174904_176047_+	glycerate kinase	W6LM47	Streptococcus_phage	5.1e-51	41.7
174084:174132	attR	NA	NA	NA	NA
AWC27153.1\|176244_177138_+	arginase	A0A1V0SJM8	Klosneuvirus	7.9e-23	31.1
AWC27154.1\|177391_178222_+	TIGR00159 family protein	NA	NA	NA	NA
AWC27155.1\|178214_179660_+	hypothetical protein	NA	NA	NA	NA
AWC27156.1\|179652_180999_+	phosphoglucosamine mutase	NA	NA	NA	NA
AWC27157.1\|181483_183286_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	Q84421	Paramecium_bursaria_Chlorella_virus	3.1e-103	40.3
AWC27158.1\|183516_184188_-	hypothetical protein	A0A146ICT8	Staphylococcus_phage	1.1e-16	55.6
AWC27159.1\|184613_185366_-\|transposase	transposase	A0A059NT77	Lactococcus_phage	2.7e-56	46.9
AWC27160.1\|185355_186651_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	8.5e-10	27.1
AWC27161.1\|187522_188392_+	hypothetical protein	A0A1X9I6E0	Streptococcus_phage	1.6e-07	26.1
AWC27162.1\|188832_190026_+	radical SAM protein	NA	NA	NA	NA
AWC27163.1\|190018_191944_+	hypothetical protein	NA	NA	NA	NA
AWC27164.1\|191936_192527_+	radical SAM protein	NA	NA	NA	NA
AWC27165.1\|192513_193323_+	hypothetical protein	NA	NA	NA	NA
AWC27166.1\|194829_195534_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWC27167.1\|196050_196794_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWC27168.1\|197259_197523_+	hypothetical protein	NA	NA	NA	NA
AWC27169.1\|197703_197856_+	hypothetical protein	NA	NA	NA	NA
AWC27170.1\|198159_198816_+	hypothetical protein	NA	NA	NA	NA
AWC30759.1\|199049_199463_+	DUF1648 domain-containing protein	NA	NA	NA	NA
AWC27171.1\|200456_201623_+	MFS transporter	NA	NA	NA	NA
AWC27172.1\|201628_202090_+	hypothetical protein	NA	NA	NA	NA
AWC27173.1\|202092_202905_+	hypothetical protein	NA	NA	NA	NA
AWC27174.1\|202938_203220_+	hypothetical protein	NA	NA	NA	NA
AWC27175.1\|203224_204217_+	hypothetical protein	NA	NA	NA	NA
AWC27176.1\|204221_204476_+	hypothetical protein	NA	NA	NA	NA
AWC27177.1\|204472_205636_+	hypothetical protein	NA	NA	NA	NA
AWC27178.1\|205654_206551_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
AWC27179.1\|206538_206889_+	hypothetical protein	NA	NA	NA	NA
AWC27180.1\|206906_207638_+	adenylyltransferase	S4VW33	Pandoravirus	4.1e-09	31.3
AWC27181.1\|207778_208144_+	hypothetical protein	NA	NA	NA	NA
AWC27182.1\|208153_208357_+	hypothetical protein	NA	NA	NA	NA
AWC27183.1\|208298_208466_-	hypothetical protein	NA	NA	NA	NA
AWC30760.1\|209058_209481_+	hypothetical protein	NA	NA	NA	NA
AWC27184.1\|209837_210989_+\|transposase	transposase	S6AND0	Bacillus_phage	9.1e-173	80.4

DBSCAN-SWA_2

287346 : 295324

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC27251.1\|287346_287631_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	5.8e-20	52.7
AWC27252.1\|287665_289294_+	molecular chaperone GroEL	A0A219YK78	uncultured_virus	1.5e-157	56.9
AWC27253.1\|289720_291268_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.2e-20	30.6
AWC27254.1\|291641_292967_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.4e-46	31.8
AWC27255.1\|293109_293811_+	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.6e-41	38.7
AWC30763.1\|293836_295324_+	sensor histidine kinase	W8CYF6	Bacillus_phage	1.3e-33	31.2

DBSCAN-SWA_3

328302 : 336674

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC27266.1\|328302_329604_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.0e-19	31.6
AWC27267.1\|329698_330418_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	9.8e-48	43.9
AWC27268.1\|330410_330665_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AWC27269.1\|330661_331345_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AWC27270.1\|331328_333548_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.0e-160	41.2
AWC27271.1\|333532_334948_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.6e-54	35.2
AWC27272.1\|335050_336094_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.7e-70	48.0
AWC27273.1\|336086_336674_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.6e-24	34.2

DBSCAN-SWA_4

758197 : 796384

Thermus_phage(20.0%)

transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC27616.1\|758197_759328_+\|transposase	transposase	S6C485	Thermus_phage	1.2e-12	32.1
AWC27617.1\|759331_761422_+\|transposase	transposase	NA	NA	NA	NA
AWC27618.1\|761423_761804_+\|transposase	transposase	NA	NA	NA	NA
AWC27619.1\|761882_762356_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
AWC27620.1\|762591_763290_-	recombinase	M9Q1K0	Clostridium_phage	2.9e-12	25.4
AWC27621.1\|763531_763939_+	transcriptional repressor	NA	NA	NA	NA
AWC27622.1\|763953_764925_+	ornithine cyclodeaminase	NA	NA	NA	NA
AWC27623.1\|764939_766052_-	hypothetical protein	NA	NA	NA	NA
AWC27624.1\|766135_766507_+	hypothetical protein	NA	NA	NA	NA
AWC27625.1\|767060_767717_-	hypothetical protein	NA	NA	NA	NA
AWC27626.1\|768042_768441_+	MarR family transcriptional regulator	NA	NA	NA	NA
AWC27627.1\|768591_769446_+	patatin family protein	NA	NA	NA	NA
AWC27628.1\|769581_770883_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.5e-51	34.1
AWC27629.1\|771170_772037_+	NAD(P)-dependent oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	6.6e-59	43.3
AWC27630.1\|772208_772970_+	L,D-transpeptidase	NA	NA	NA	NA
AWC27631.1\|773062_773335_+	hypothetical protein	NA	NA	NA	NA
AWC27632.1\|773385_773601_-	DUF1540 domain-containing protein	NA	NA	NA	NA
AWC27633.1\|773672_774083_-	thioredoxin	NA	NA	NA	NA
AWC27634.1\|774095_774515_-	disulfide bond formation protein B	NA	NA	NA	NA
AWC27635.1\|774645_775521_-	LytR family transcriptional regulator	NA	NA	NA	NA
AWC27636.1\|775708_775957_-	hypothetical protein	NA	NA	NA	NA
AWC27637.1\|776057_776555_-	hypothetical protein	NA	NA	NA	NA
AWC27638.1\|776609_777710_-	spore gernimation protein GerB	NA	NA	NA	NA
AWC27639.1\|777722_778805_-	Ger(x)C family spore germination protein	NA	NA	NA	NA
AWC27640.1\|778801_780313_-	spore germination protein	NA	NA	NA	NA
AWC27641.1\|780588_781149_+	nitroreductase	NA	NA	NA	NA
AWC27642.1\|781833_783246_+	stage V sporulation protein R	NA	NA	NA	NA
AWC27643.1\|783445_783886_-	hypothetical protein	NA	NA	NA	NA
AWC27644.1\|784041_785208_-	LytR family transcriptional regulator	NA	NA	NA	NA
AWC27645.1\|785555_787211_-	sodium:phosphate symporter	NA	NA	NA	NA
AWC27646.1\|787553_788756_-	MFS transporter	NA	NA	NA	NA
AWC27647.1\|789076_790165_+	DUF871 domain-containing protein	NA	NA	NA	NA
AWC27648.1\|790205_791387_-	ABC transporter permease	NA	NA	NA	NA
AWC27649.1\|791389_792064_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.1e-36	39.5
AWC27650.1\|792060_793164_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
AWC27651.1\|793783_795100_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
AWC27652.1\|795314_795884_-\|coat	spore coat protein CotJC	NA	NA	NA	NA
AWC27653.1\|795896_796160_-\|coat	spore coat protein CotJB	NA	NA	NA	NA
AWC27654.1\|796168_796384_-\|coat	spore coat associated protein CotJA	NA	NA	NA	NA

DBSCAN-SWA_5

1109603 : 1177055

Bacillus_phage(36.36%)

bacteriocin,integrase,coat

attL 1170489:1170506|attR 1177925:1177942

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC27913.1\|1109603_1110341_+\|coat	spore coat protein	I7I009	Enterobacteria_phage	2.8e-50	44.7
AWC27914.1\|1110349_1110898_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A218MN57	uncultured_virus	1.7e-31	43.2
AWC27915.1\|1110909_1111881_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	8.5e-71	42.9
AWC27916.1\|1111892_1112744_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	9.5e-42	40.2
AWC27917.1\|1112947_1113448_-	hypothetical protein	NA	NA	NA	NA
AWC27918.1\|1113882_1114356_-\|coat	spore coat protein	NA	NA	NA	NA
AWC27919.1\|1114522_1116577_-	ATP-dependent helicase	S5MMD7	Bacillus_phage	6.2e-79	31.9
AWC27920.1\|1117102_1117621_-	hypothetical protein	NA	NA	NA	NA
AWC27921.1\|1117713_1118445_-	esterase family protein	NA	NA	NA	NA
AWC27922.1\|1118665_1119577_+	EamA/RhaT family transporter	NA	NA	NA	NA
AWC27923.1\|1119797_1120187_-	hypothetical protein	A0A0E3TB73	Enterococcus_phage	8.2e-09	36.6
AWC27924.1\|1120358_1121825_-	sodium/proline symporter PutP	NA	NA	NA	NA
AWC27925.1\|1123657_1125151_+	lactate permease	NA	NA	NA	NA
AWC27926.1\|1125255_1125939_+	DUF2278 domain-containing protein	NA	NA	NA	NA
AWC27927.1\|1125985_1126819_-	hypothetical protein	NA	NA	NA	NA
AWC27928.1\|1126947_1127694_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
AWC27929.1\|1127868_1129203_+	CoA-disulfide reductase	NA	NA	NA	NA
AWC27930.1\|1129331_1129742_+	DUF3908 domain-containing protein	NA	NA	NA	NA
AWC27931.1\|1129955_1131500_-	NADH oxidase	NA	NA	NA	NA
AWC27932.1\|1131560_1133513_-\|bacteriocin	bacteriocin biosynthesis protein SagD	NA	NA	NA	NA
AWC27933.1\|1133506_1135432_-\|bacteriocin	putative thiazole-containing bacteriocin maturation protein	NA	NA	NA	NA
AWC27934.1\|1135590_1136835_-	dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
AWC27935.1\|1136955_1139832_-	2-oxoglutarate dehydrogenase subunit E1	NA	NA	NA	NA
AWC27936.1\|1140800_1140983_+	DUF3976 domain-containing protein	NA	NA	NA	NA
AWC27937.1\|1141044_1141929_-	LysR family transcriptional regulator	NA	NA	NA	NA
AWC27938.1\|1142115_1143042_+	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase	NA	NA	NA	NA
AWC27939.1\|1143111_1144635_+	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase	NA	NA	NA	NA
AWC27940.1\|1144688_1146161_+	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component	NA	NA	NA	NA
AWC27941.1\|1146180_1147164_+	3,4-dihydroxyphenylacetate 2,3-dioxygenase	NA	NA	NA	NA
AWC27942.1\|1147221_1148088_+	cytidyltransferase	NA	NA	NA	NA
AWC27943.1\|1148148_1148478_+	DUF485 domain-containing protein	NA	NA	NA	NA
AWC27944.1\|1148467_1150018_+	cation acetate symporter	NA	NA	NA	NA
AWC27945.1\|1150038_1150830_+	4-hydroxyphenylacetate isomerase	NA	NA	NA	NA
AWC27946.1\|1150826_1151585_+	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase	NA	NA	NA	NA
AWC27947.1\|1151657_1152056_+	5-carboxymethyl-2-hydroxymuconate isomerase	NA	NA	NA	NA
AWC27948.1\|1152374_1153487_+	tetratricopeptide repeat-containing protein	A0A2H4J8G3	uncultured_Caudovirales_phage	2.4e-93	49.1
AWC27949.1\|1154137_1154506_+	NUDIX domain-containing protein	NA	NA	NA	NA
AWC27950.1\|1155330_1155537_+	hypothetical protein	NA	NA	NA	NA
AWC27951.1\|1156187_1156505_+	DUF3884 domain-containing protein	NA	NA	NA	NA
AWC30790.1\|1158063_1158540_+	hypothetical protein	NA	NA	NA	NA
AWC27952.1\|1158562_1158970_+	hypothetical protein	NA	NA	NA	NA
AWC27953.1\|1160377_1160653_-	hypothetical protein	NA	NA	NA	NA
AWC27954.1\|1161650_1162571_-	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
AWC27955.1\|1162770_1162998_-	hypothetical protein	NA	NA	NA	NA
AWC27956.1\|1163047_1163308_-	hypothetical protein	NA	NA	NA	NA
AWC27957.1\|1163443_1163698_+	hypothetical protein	NA	NA	NA	NA
AWC27958.1\|1164204_1164858_+	hypothetical protein	NA	NA	NA	NA
AWC27959.1\|1165055_1165331_+	hypothetical protein	NA	NA	NA	NA
AWC27960.1\|1165648_1166743_-	tetratricopeptide repeat-containing protein	A0A2H4J8G3	uncultured_Caudovirales_phage	1.2e-100	51.8
AWC27961.1\|1167005_1167377_+\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	2.1e-25	54.4
AWC27962.1\|1167894_1168599_-	hypothetical protein	NA	NA	NA	NA
AWC27963.1\|1168983_1169157_-	hypothetical protein	NA	NA	NA	NA
AWC27964.1\|1169163_1169463_-	hypothetical protein	NA	NA	NA	NA
AWC27965.1\|1169508_1169742_-	TIGR04197 family type VII secretion effector	NA	NA	NA	NA
1170489:1170506	attL	NA	NA	NA	NA
AWC27966.1\|1170517_1172224_-	hypothetical protein	NA	NA	NA	NA
AWC27967.1\|1172292_1173414_-	DUF4297 domain-containing protein	NA	NA	NA	NA
AWC27968.1\|1173536_1174238_-	hypothetical protein	NA	NA	NA	NA
AWC27969.1\|1174656_1175733_+	replication initiation factor	NA	NA	NA	NA
AWC27970.1\|1175747_1175945_+	DNA-binding protein	A0A1B0T6C2	Bacillus_phage	4.3e-06	41.2
AWC27971.1\|1175945_1177055_+\|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	2.6e-60	40.9
1177925:1177942	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2353167 : 2421143

Bacillus_phage(36.84%)

bacteriocin,tail,integrase,holin,transposase

attL 2348333:2348349|attR 2382143:2382159

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2348333:2348349	attL	NA	NA	NA	NA
AWC29016.1\|2353167_2354315_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.8e-99	66.4
AWC29017.1\|2354591_2356760_-\|bacteriocin	bacteriocin-associated protein	NA	NA	NA	NA
AWC29018.1\|2356883_2357072_-	hypothetical protein	NA	NA	NA	NA
AWC29019.1\|2357056_2357326_-	hypothetical protein	NA	NA	NA	NA
AWC29020.1\|2358048_2358402_+\|integrase	integrase	A0A2H4J6I5	uncultured_Caudovirales_phage	6.5e-05	34.1
AWC29021.1\|2358422_2358671_-	DUF4176 domain-containing protein	NA	NA	NA	NA
AWC29022.1\|2358671_2358860_-	hypothetical protein	NA	NA	NA	NA
AWC29023.1\|2358890_2359082_-	hypothetical protein	NA	NA	NA	NA
AWC29024.1\|2360369_2360732_-	DUF3958 domain-containing protein	NA	NA	NA	NA
AWC29025.1\|2360772_2361048_-	TIGR04197 family type VII secretion effector	NA	NA	NA	NA
AWC29026.1\|2361752_2364323_-	permease	NA	NA	NA	NA
AWC29027.1\|2364340_2365087_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-31	37.1
AWC29028.1\|2365452_2365776_-	hypothetical protein	NA	NA	NA	NA
AWC29029.1\|2365783_2366308_-	hypothetical protein	NA	NA	NA	NA
AWC29030.1\|2368441_2368825_-	hypothetical protein	NA	NA	NA	NA
AWC29031.1\|2369113_2369839_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.3e-36	37.8
AWC29032.1\|2370403_2370592_-	transcriptional regulator	S5M643	Brevibacillus_phage	3.7e-07	42.4
AWC29033.1\|2370581_2370905_-	hypothetical protein	NA	NA	NA	NA
AWC29034.1\|2372161_2373142_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
AWC29035.1\|2373204_2373453_-	hypothetical protein	A0A288WFY7	Bacillus_phage	3.9e-12	46.2
AWC29036.1\|2373725_2374775_-	oxidoreductase	NA	NA	NA	NA
AWC29037.1\|2375257_2375656_+	DUF2871 domain-containing protein	NA	NA	NA	NA
AWC29038.1\|2376554_2376815_-	DUF2642 domain-containing protein	NA	NA	NA	NA
AWC29039.1\|2376954_2377617_-	bacillithiol biosynthesis deacetylase BshB2	NA	NA	NA	NA
AWC29040.1\|2377632_2377983_-	DUF1806 domain-containing protein	NA	NA	NA	NA
AWC29041.1\|2378224_2379550_+	hypothetical protein	NA	NA	NA	NA
AWC29042.1\|2379889_2380417_-	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	4.8e-60	66.3
AWC29043.1\|2380423_2382325_-	mannonate oxidoreductase	F2Y0V3	Organic_Lake_phycodnavirus	3.4e-15	25.0
2382143:2382159	attR	NA	NA	NA	NA
AWC29044.1\|2382877_2383669_+	arylamine N-acetyltransferase	NA	NA	NA	NA
AWC29045.1\|2383797_2385585_+	oligoendopeptidase F	NA	NA	NA	NA
AWC29046.1\|2385770_2387003_-	MFS transporter	NA	NA	NA	NA
AWC29047.1\|2387106_2387970_+	LysR family transcriptional regulator	NA	NA	NA	NA
AWC29048.1\|2388137_2389196_+	acyltransferase	NA	NA	NA	NA
AWC29049.1\|2389240_2390185_-	glycerophosphodiester phosphodiesterase	A0A076G4Q2	Staphylococcus_phage	2.4e-38	35.0
AWC29050.1\|2390663_2391206_-	N-acetyltransferase	NA	NA	NA	NA
AWC29051.1\|2391456_2391870_-	hypothetical protein	NA	NA	NA	NA
AWC29052.1\|2392412_2393261_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-08	47.9
AWC29053.1\|2393679_2394318_-	hypothetical protein	NA	NA	NA	NA
AWC29054.1\|2394344_2395157_-	hypothetical protein	NA	NA	NA	NA
AWC29055.1\|2395638_2397018_+	chitin-binding protein	A0A0K1Y848	Apis_mellifera_filamentous_virus	1.4e-21	35.7
AWC29056.1\|2397171_2398842_-	peptidase M4 family protein	NA	NA	NA	NA
AWC29057.1\|2399491_2400967_+	SELO family protein	A0A075BSJ0	Microcystis_phage	3.4e-47	30.7
AWC29058.1\|2401082_2402468_-	2-hydroxy-acid oxidase	NA	NA	NA	NA
AWC29059.1\|2402892_2403570_-	methyltransferase	G3MA03	Bacillus_virus	8.1e-20	43.3
AWC29060.1\|2404385_2405297_-	hypothetical protein	NA	NA	NA	NA
AWC29061.1\|2405702_2406050_+	hypothetical protein	NA	NA	NA	NA
AWC29062.1\|2406191_2407268_+	hypothetical protein	NA	NA	NA	NA
AWC29063.1\|2408538_2408871_-	hypothetical protein	NA	NA	NA	NA
AWC29064.1\|2409040_2409253_+	XRE family transcriptional regulator	A0A076G7N2	Bacillus_phage	9.0e-10	51.5
AWC29065.1\|2409352_2409937_+	hypothetical protein	NA	NA	NA	NA
AWC29066.1\|2409977_2410802_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J966	uncultured_Caudovirales_phage	7.2e-79	51.1
AWC29067.1\|2410817_2411048_-\|holin	phage holin	A0A0S2MVE8	Bacillus_phage	4.1e-24	73.3
AWC29068.1\|2411062_2411347_-	hypothetical protein	NA	NA	NA	NA
AWC29069.1\|2411386_2415883_-	hypothetical protein	A0A0M4RER0	Bacillus_phage	2.8e-262	45.3
AWC29070.1\|2415882_2417385_-\|tail	phage tail protein	A0A1B1P7W7	Bacillus_phage	5.0e-203	73.9
AWC29071.1\|2417399_2421143_-\|tail	phage tail tape measure protein	A6M961	Geobacillus_virus	8.1e-53	38.8

DBSCAN-SWA_7

2429485 : 2442596

Bacillus_phage(41.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC29085.1\|2429485_2431189_-	hypothetical protein	A0A142F1L6	Bacillus_phage	2.9e-159	50.5
AWC29086.1\|2431188_2431662_-	hypothetical protein	NA	NA	NA	NA
AWC29087.1\|2432730_2433555_-	hypothetical protein	NA	NA	NA	NA
AWC29088.1\|2433950_2434517_-	hypothetical protein	A0A2H4J2L4	uncultured_Caudovirales_phage	9.7e-35	45.8
AWC29089.1\|2434528_2434906_-	hypothetical protein	A0A0N9RZI0	Paenibacillus_phage	2.0e-15	43.1
AWC29090.1\|2435290_2435929_-	hypothetical protein	NA	NA	NA	NA
AWC29091.1\|2435940_2436174_-	glutaredoxin family protein	A0A1B1P8E0	Bacillus_phage	1.2e-23	64.5
AWC29092.1\|2436170_2436776_-	hypothetical protein	A0A2H4JAZ2	uncultured_Caudovirales_phage	7.7e-38	41.2
AWC29093.1\|2436836_2437463_-	hypothetical protein	J9Q953	Bacillus_phage	1.4e-34	43.2
AWC29094.1\|2437464_2438097_-	hypothetical protein	NA	NA	NA	NA
AWC29095.1\|2438239_2438548_-	transglycosylase	A0A0K2CZP5	Paenibacillus_phage	2.6e-05	36.9
AWC29096.1\|2438547_2438943_-	alpha/beta hydrolase	A0A2H4IZM2	uncultured_Caudovirales_phage	6.1e-44	68.9
AWC29097.1\|2439228_2439756_-	hypothetical protein	A0A0N9ST03	Paenibacillus_phage	3.2e-08	44.6
AWC29098.1\|2439752_2439977_-	hypothetical protein	U5Q038	Bacillus_phage	8.3e-22	70.6
AWC29099.1\|2439976_2441023_-	hypothetical protein	A0A0N9SHN6	Paenibacillus_phage	4.8e-88	58.6
AWC29100.1\|2441036_2441192_-	hypothetical protein	NA	NA	NA	NA
AWC29101.1\|2442092_2442596_-	hypothetical protein	A0A0A0RUN2	Bacillus_phage	3.8e-30	47.3

DBSCAN-SWA_8

2448204 : 2459001

uncultured_Caudovirales_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC29106.1\|2448204_2449428_-	hypothetical protein	A0A288WGM1	Bacillus_phage	9.9e-101	47.8
AWC29107.1\|2449542_2449746_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWC30846.1\|2449809_2449995_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWC29108.1\|2450002_2451019_-	hypothetical protein	A0A2H4J6E6	uncultured_Caudovirales_phage	6.8e-71	43.2
AWC29109.1\|2451045_2452389_-	DNA helicase	A0A2H4IZL9	uncultured_Caudovirales_phage	7.5e-134	55.8
AWC29110.1\|2452485_2452770_-	hypothetical protein	A0A0H3V0M3	Geobacillus_virus	5.4e-10	44.0
AWC29111.1\|2453017_2453434_-	hypothetical protein	A0A0K2CNU6	Brevibacillus_phage	8.5e-12	57.1
AWC29112.1\|2453454_2453706_-	hypothetical protein	NA	NA	NA	NA
AWC29113.1\|2453752_2454004_-	hypothetical protein	NA	NA	NA	NA
AWC29114.1\|2454050_2454239_-	hypothetical protein	NA	NA	NA	NA
AWC29115.1\|2454602_2455367_-	DNA replication protein	A0A0N7GFF0	Paenibacillus_phage	3.7e-77	56.5
AWC29116.1\|2455366_2456041_-	DUF723 domain-containing protein	NA	NA	NA	NA
AWC30847.1\|2456056_2456443_-	hypothetical protein	A0A2H4J134	uncultured_Caudovirales_phage	5.5e-13	36.2
AWC29117.1\|2456448_2456781_-	hypothetical protein	NA	NA	NA	NA
AWC29118.1\|2456767_2456926_-	Fur-regulated basic protein FbpA	NA	NA	NA	NA
AWC29119.1\|2457007_2457352_-	hypothetical protein	NA	NA	NA	NA
AWC29120.1\|2457481_2458096_-	hypothetical protein	NA	NA	NA	NA
AWC29121.1\|2458107_2459001_-	hypothetical protein	A0A0N9RZE9	Paenibacillus_phage	5.5e-16	30.9

DBSCAN-SWA_9

2620688 : 2636169

Bacillus_phage(72.73%)

integrase

attL 2632403:2632417|attR 2638927:2638941

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC29262.1\|2620688_2620898_-	DNA-binding protein	A0A1Z1LZP5	Bacillus_phage	1.4e-15	62.1
AWC29263.1\|2621145_2621361_-	hypothetical protein	NA	NA	NA	NA
AWC29264.1\|2621691_2622159_-	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	3.5e-30	51.8
AWC30852.1\|2622896_2623172_-	DNA-binding protein	A0A2H4JBQ8	uncultured_Caudovirales_phage	2.0e-09	43.2
AWC29265.1\|2623140_2623338_-	hypothetical protein	NA	NA	NA	NA
AWC29266.1\|2623411_2623603_-	hypothetical protein	NA	NA	NA	NA
AWC29267.1\|2623701_2624082_-	ArpU family transcriptional regulator	A0A0M4R397	Bacillus_phage	4.1e-53	84.7
AWC29268.1\|2624086_2624374_-	hypothetical protein	A6M999	Geobacillus_virus	4.2e-34	70.2
AWC29269.1\|2624403_2624604_-	hypothetical protein	NA	NA	NA	NA
AWC29270.1\|2624635_2624842_-	hypothetical protein	NA	NA	NA	NA
AWC29271.1\|2624883_2625126_-	hypothetical protein	A0A0S2MV78	Bacillus_phage	9.9e-29	73.8
AWC29272.1\|2625155_2625383_-	hypothetical protein	A0A288WFX6	Bacillus_phage	3.5e-36	98.7
AWC29273.1\|2625423_2626062_-	hypothetical protein	A0A0K2CP60	Brevibacillus_phage	1.5e-52	49.0
AWC29274.1\|2626093_2626297_-	hypothetical protein	NA	NA	NA	NA
AWC29275.1\|2626710_2627499_-	hypothetical protein	A0A0M4RU33	Bacillus_phage	1.5e-28	39.7
AWC29276.1\|2627491_2627680_-	hypothetical protein	A0A0M4RD83	Bacillus_phage	3.6e-10	56.7
AWC29277.1\|2627664_2627880_-	hypothetical protein	NA	NA	NA	NA
AWC29278.1\|2627890_2628763_-	DNA replication protein	A0A0M4RD64	Bacillus_phage	5.6e-114	72.0
AWC29279.1\|2628692_2629481_-	phage replication protein	A0A0M4S6Y4	Bacillus_phage	9.6e-89	76.8
AWC29280.1\|2629481_2629751_-	hypothetical protein	A0A0M4S680	Bacillus_phage	5.3e-39	83.1
AWC29281.1\|2629731_2630586_-	hypothetical protein	Q38143	Bacillus_phage	5.4e-53	44.6
AWC29282.1\|2631736_2631976_-	hypothetical protein	A0A0M4S677	Bacillus_phage	2.3e-22	77.9
AWC29283.1\|2632302_2632485_-	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	4.4e-05	43.5
2632403:2632417	attL	NA	NA	NA	NA
AWC29284.1\|2632519_2632795_-	group-specific protein	S5MC08	Brevibacillus_phage	3.6e-27	59.3
AWC29285.1\|2632821_2633658_-	hypothetical protein	A0A0M5M1L9	Bacillus_phage	2.6e-129	84.9
AWC29286.1\|2633654_2633843_-	XRE family transcriptional regulator	A0A1C8E998	Bacillus_phage	2.0e-21	83.6
AWC29287.1\|2634115_2634535_+	XRE family transcriptional regulator	A0A1C8E9A4	Bacillus_phage	1.1e-64	89.2
AWC29288.1\|2634549_2634975_+	ImmA/IrrE family metallo-endopeptidase	A0A1C8E988	Bacillus_phage	1.2e-72	92.9
AWC29289.1\|2635011_2636169_+\|integrase	site-specific integrase	A0A0S2SXP1	Bacillus_phage	1.2e-76	76.1
2638927:2638941	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2817321 : 2891288

Bacillus_phage(77.78%)

tail,terminase,protease,head,tRNA,capsid,holin,portal,integrase

attL 2848863:2848880|attR 2898009:2898026

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWC29442.1\|2817321_2820087_-\|tRNA	isoleucine--tRNA ligase	A0A2K9L9X8	Tupanvirus	2.8e-87	27.3
AWC29443.1\|2820431_2820938_-	septum formation initiator	NA	NA	NA	NA
AWC29444.1\|2821030_2821804_-	RNA-binding protein	NA	NA	NA	NA
AWC29445.1\|2821818_2822082_-	YggT family protein	NA	NA	NA	NA
AWC29446.1\|2822088_2822559_-	cell division protein SepF	NA	NA	NA	NA
AWC29447.1\|2822577_2823252_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
AWC29448.1\|2823258_2824068_-	laccase domain-containing protein	NA	NA	NA	NA
AWC29449.1\|2824185_2824464_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
AWC29450.1\|2824727_2825507_-	RNA polymerase sporulation sigma factor SigG	A0A0Y0AU18	Bacillus_phage	3.4e-46	43.4
AWC29451.1\|2825698_2826418_-	RNA polymerase sporulation sigma factor SigE	A0A2H4JC68	uncultured_Caudovirales_phage	2.5e-19	42.9
AWC29452.1\|2826437_2827364_-	sigma-E processing peptidase SpoIIGA	NA	NA	NA	NA
AWC29453.1\|2827579_2828734_-	cell division protein FtsZ	NA	NA	NA	NA
AWC29454.1\|2828772_2830077_-	cell division protein FtsA	NA	NA	NA	NA
AWC29455.1\|2830477_2831245_-	cell division protein DivIB	NA	NA	NA	NA
AWC30859.1\|2831342_2832248_-	UDP-N-acetylenolpyruvoylglucosamine reductase	NA	NA	NA	NA
AWC29456.1\|2832308_2833403_-	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase	NA	NA	NA	NA
AWC30860.1\|2833587_2834679_-	stage V sporulation protein E	NA	NA	NA	NA
AWC29457.1\|2834770_2836126_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
AWC29458.1\|2836126_2837101_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
AWC29459.1\|2837123_2838599_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
AWC29460.1\|2838871_2840788_-	stage V sporulation protein D	NA	NA	NA	NA
AWC30861.1\|2840885_2843036_-	dihydropteridine reductase	NA	NA	NA	NA
AWC29461.1\|2843058_2843415_-	cell division protein FtsL	NA	NA	NA	NA
AWC29462.1\|2843430_2844363_-	ribosomal RNA small subunit methyltransferase H	NA	NA	NA	NA
AWC30862.1\|2844726_2846343_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
AWC30863.1\|2846422_2847307_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
AWC29463.1\|2847608_2848082_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWC29464.1\|2848177_2848699_-	RsfA family transcriptional regulator	G3MB11	Bacillus_virus	4.0e-11	47.8
2848863:2848880	attL	NA	NA	NA	NA
AWC29465.1\|2848958_2849132_-	50S ribosomal protein L32	NA	NA	NA	NA
AWC29466.1\|2849193_2849694_-	hypothetical protein	NA	NA	NA	NA
AWC29467.1\|2849975_2850596_-	hypothetical protein	Q2LIA9	Bacillus_phage	1.0e-85	76.8
AWC29468.1\|2850537_2851719_-	cell division protein FtsK	Q3HKZ7	Bacillus_phage	3.0e-195	84.5
AWC29469.1\|2851836_2852019_-	hypothetical protein	Q2I8E2	Bacillus_phage	2.2e-20	88.3
AWC29470.1\|2852015_2852324_-	hypothetical protein	A0A288WG08	Bacillus_phage	3.8e-41	78.4
AWC29471.1\|2852507_2852717_+	XRE family transcriptional regulator	Q2I8E4	Bacillus_phage	2.7e-22	79.4
AWC29472.1\|2852719_2853208_+	hypothetical protein	Q3HL01	Bacillus_phage	8.1e-46	61.7
AWC29473.1\|2853243_2854308_-	N-acetylmuramoyl-L-alanine amidase	A0A0A7AQV3	Bacillus_phage	2.3e-178	85.9
AWC29474.1\|2854304_2854544_-\|holin	holin	A0A2H4J378	uncultured_Caudovirales_phage	1.2e-29	87.3
AWC29475.1\|2854543_2854780_-	hypothetical protein	A0A2H4J382	uncultured_Caudovirales_phage	1.2e-07	78.2
AWC29476.1\|2854821_2858853_-	peptidase S74	H0USX5	Bacillus_phage	1.7e-242	44.9
AWC29477.1\|2858849_2860343_-\|tail	phage tail protein	A0A2H4JC38	uncultured_Caudovirales_phage	1.2e-254	83.7
AWC29478.1\|2860351_2864392_-\|tail	phage tail tape measure protein	H0USX3	Bacillus_phage	0.0e+00	75.1
AWC29479.1\|2864608_2864923_-	hypothetical protein	A0A288WFU6	Bacillus_phage	1.8e-35	70.2
AWC29480.1\|2864971_2865583_-\|tail	phage tail protein	A0A2H4J8F3	uncultured_Caudovirales_phage	8.4e-101	94.5
AWC29481.1\|2865583_2865943_-	DUF3168 domain-containing protein	A0A0S2GLE3	Bacillus_phage	1.4e-55	90.8
AWC29482.1\|2865939_2866374_-	hypothetical protein	A0A288WGB7	Bacillus_phage	8.2e-66	84.9
AWC29483.1\|2866366_2866690_-\|head,tail	head-tail adaptor protein	A0A288WG18	Bacillus_phage	8.0e-50	85.0
AWC29484.1\|2866686_2866977_-\|head,tail	phage gp6-like head-tail connector protein	A0A288WGQ6	Bacillus_phage	3.6e-41	88.5
AWC29485.1\|2866994_2868170_-\|capsid	phage major capsid protein	A0A288WG01	Bacillus_phage	2.5e-186	88.0
AWC30864.1\|2868211_2868784_-\|head,protease	HK97 family phage prohead protease	Q2I8F8	Bacillus_phage	1.3e-95	91.1
AWC29486.1\|2868773_2870084_-\|portal	phage portal protein	Q2LIC9	Bacillus_phage	6.4e-215	89.2
AWC29487.1\|2870099_2871797_-\|terminase	terminase large subunit	A0A288WFW5	Bacillus_phage	0.0e+00	91.7
AWC29488.1\|2871793_2872276_-\|terminase	phage terminase small subunit P27 family	Q2I8G1	Bacillus_phage	1.4e-74	92.5
AWC29489.1\|2872375_2872759_-	HNH endonuclease	Q2I8B2	Bacillus_phage	2.2e-62	90.6
AWC29490.1\|2872824_2873064_-	hypothetical protein	NA	NA	NA	NA
AWC29491.1\|2873730_2873985_-	hypothetical protein	A0A288WG25	Bacillus_phage	2.5e-30	73.8
AWC29492.1\|2874004_2874196_-	hypothetical protein	A0A288WFV5	Bacillus_phage	1.7e-23	88.9
AWC29493.1\|2874201_2874420_-	hypothetical protein	D2XR60	Bacillus_phage	3.3e-23	73.6
AWC29494.1\|2874714_2875092_-	ArpU family transcriptional regulator	Q9ZXB9	Bacillus_phage	1.0e-16	39.7
AWC30865.1\|2875149_2875470_-	hypothetical protein	NA	NA	NA	NA
AWC30866.1\|2875510_2875738_-	hypothetical protein	A0A288WFX6	Bacillus_phage	2.2e-22	68.0
AWC29495.1\|2875783_2876329_-	hypothetical protein	A0A1I9S5V4	Bacillus_phage	3.5e-66	78.0
AWC29496.1\|2876389_2876653_-	hypothetical protein	NA	NA	NA	NA
AWC29497.1\|2877413_2877812_-	hypothetical protein	NA	NA	NA	NA
AWC29498.1\|2877820_2878711_-	zinc-finger domain-containing protein	NA	NA	NA	NA
AWC29499.1\|2878781_2879492_-	2-methylcitrate dehydratase	NA	NA	NA	NA
AWC29500.1\|2879511_2879925_-	DUF1064 domain-containing protein	A0A2P1JTY5	Anoxybacillus_phage	1.2e-34	58.5
AWC29501.1\|2879917_2880412_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	A0A1B1P8C0	Bacillus_phage	3.2e-58	70.6
AWC29502.1\|2880628_2881081_-	MFS transporter	A0A0A7AQW3	Bacillus_phage	3.3e-33	43.4
AWC29503.1\|2881095_2881578_-	hypothetical protein	NA	NA	NA	NA
AWC29504.1\|2881558_2881753_-	hypothetical protein	NA	NA	NA	NA
AWC30867.1\|2881758_2882451_-	DNA replication protein	A0A0S2GLK2	Bacillus_phage	7.9e-63	50.6
AWC29505.1\|2882521_2883487_-	DnaD domain protein	H0USU2	Bacillus_phage	9.7e-43	51.9
AWC29506.1\|2883661_2884468_-	recombinase RecT	S6AVW6	Thermus_phage	3.4e-97	66.9
AWC29507.1\|2884467_2884707_-	hypothetical protein	NA	NA	NA	NA
AWC29508.1\|2884721_2885657_-	hypothetical protein	S6C475	Thermus_phage	1.9e-99	59.5
AWC29509.1\|2885738_2885954_-	hypothetical protein	NA	NA	NA	NA
AWC30868.1\|2886129_2886423_-	hypothetical protein	A0A0S2GLB6	Bacillus_phage	1.7e-27	62.4
AWC29510.1\|2886430_2886751_-	hypothetical protein	NA	NA	NA	NA
AWC29511.1\|2886898_2887108_-	DNA-binding protein	A0A0U4IIS1	Bacillus_phage	4.4e-09	50.9
AWC30869.1\|2887230_2887440_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWC29512.1\|2887605_2887944_+	XRE family transcriptional regulator	H0UST7	Bacillus_phage	1.3e-21	53.3
AWC29513.1\|2888225_2888360_-	hypothetical protein	NA	NA	NA	NA
AWC29514.1\|2888373_2889471_-	hypothetical protein	NA	NA	NA	NA
AWC29515.1\|2890157_2891288_+\|integrase	site-specific integrase	A0A0U4JNS1	Bacillus_phage	1.7e-62	37.4
2898009:2898026	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP024100

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP024098

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection