CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029612	Enterococcus faecalis strain H25 chromosome, complete genome	2 crisprs	csa3,cas3,cas14j,DinG,DEDDh	1	3	13	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP029612_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029612_1

1901683-1901982

Orphan

NA:II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CRISPRCasFinder
AAACAACATGACTCTAAAAC	CRT
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	PILER-CR

4 spacers

The CRISPR arrays of CP029612_1

>merge|CP029612|1|1901683-1901982|CRISPRCasFinder,CRT,PILER-CR
GTGATAGTTTGTTTTTTAACAACATGACTCTAAAACGATTCCGAGTGATTCACTTTTAGCTTGTTCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAACGTTTTTAGGGATCCAAATACCTTTAAAGTTTTGGTACCATTCCAAACAACATGACTCTAAAACAGAGACAGCGGGAAAACTACGATATTCATCGTTTTGGTACCATTCCAAACAACATGACTCTAAAACCAATGTGTCTGCATTGATATGCTGAGAAATGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP029612|1|1|1901683-1901982|CRISPRCasFinder
GTGATAGTTTGTTTTTTAACAACATGACTCTAAAAC	GATTCCGAGTGATTCACTTTTAGCTTGTTC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAA
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>CP029612|1|1|1901699-1901982|CRT
TAACAACATGACTCTAAAAC	GATTCCGAGTGATTCACTTTTAGCTTGTTCGTTTTGGTACCATTCT
AAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAAGTTTTGGTACCATTCC
AAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATCGTTTTGGTACCATTCC
AAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAATGTTTTGGTACCATTCT
AAACAACATGACTCTAAAAC

>CP029612|1|1|1901749-1901982|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAA
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP029612.1\|AWQ40172.1\|1908208_1908358_-\|hypothetical-protein	unknown	unknown	unknown
CP029612.1\|AWQ40165.1\|1901435_1901534_-\|hypothetical-protein	unknown	unknown	unknown
CP029612.1\|AWQ40170.1\|1906464_1906980_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
CP029612.1\|AWQ40158.1\|1892019_1893231_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
CP029612.1\|AWQ40167.1\|1903087_1905169_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
CP029612.1\|AWQ40157.1\|1891811_1891943_-\|hypothetical-protein	unknown	unknown	unknown
CP029612.1\|AWQ40175.1\|1910176_1911322_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
CP029612.1\|AWQ40159.1\|1893259_1894165_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
CP029612.1\|AWQ40168.1\|1905299_1905665_-\|DUF1033-domain-containing-protein	unknown	unknown	gnl\|CDD\|336361
CP029612.1\|AWQ40162.1\|1897109_1898843_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
CP029612.1\|AWQ40161.1\|1895346_1897113_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
CP029612.1\|AWQ40163.1\|1898847_1899861_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
CP029612.1\|AWQ40166.1\|1902139_1903003_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
CP029612.1\|AWQ40164.1\|1899857_1901276_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
CP029612.1\|AWQ40171.1\|1906996_1908235_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
CP029612.1\|AWQ40169.1\|1905762_1906332_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
CP029612.1\|AWQ40173.1\|1908414_1909539_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
CP029612.1\|AWQ40174.1\|1909764_1910109_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|370163
CP029612.1\|AWQ40156.1\|1889282_1891706_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
CP029612.1\|AWQ40160.1\|1894286_1895267_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220

Protein	Function_ID	Function_description	E-value
CP029612.1\|AWQ40170.1\|1906464_1906980_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	5.73504e-32
CP029612.1\|AWQ40158.1\|1892019_1893231_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.21914e-122
CP029612.1\|AWQ40167.1\|1903087_1905169_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
CP029612.1\|AWQ40168.1\|1905299_1905665_-\|DUF1033-domain-containing-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
CP029612.1\|AWQ40175.1\|1910176_1911322_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.04062e-178
CP029612.1\|AWQ40159.1\|1893259_1894165_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
CP029612.1\|AWQ40163.1\|1898847_1899861_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
CP029612.1\|AWQ40161.1\|1895346_1897113_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
CP029612.1\|AWQ40166.1\|1902139_1903003_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.22379e-26
CP029612.1\|AWQ40164.1\|1899857_1901276_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
CP029612.1\|AWQ40171.1\|1906996_1908235_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.24866e-173
CP029612.1\|AWQ40169.1\|1905762_1906332_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.88451e-15
CP029612.1\|AWQ40173.1\|1908414_1909539_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
CP029612.1\|AWQ40174.1\|1909764_1910109_-\|cysteine-desulfurase	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
CP029612.1\|AWQ40156.1\|1889282_1891706_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	2.52612e-175
CP029612.1\|AWQ40160.1\|1894286_1895267_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
CP029612.1\|AWQ40162.1\|1897109_1898843_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0

>CP029612.1|AWQ40165.1|1901435_1901534_-|hypothetical-protein
MIEEREEILGAPKKIVRNASVLFGFCLRKLYT
>CP029612.1|AWQ40164.1|1899857_1901276_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>CP029612.1|AWQ40163.1|1898847_1899861_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>CP029612.1|AWQ40162.1|1897109_1898843_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGITLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>CP029612.1|AWQ40161.1|1895346_1897113_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYVALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEQQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVTQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>CP029612.1|AWQ40160.1|1894286_1895267_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>CP029612.1|AWQ40159.1|1893259_1894165_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>CP029612.1|AWQ40158.1|1892019_1893231_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVNEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>CP029612.1|AWQ40157.1|1891811_1891943_-|hypothetical-protein
MLFNFWRISAYFRRSWFCSRRLSVFERGAKIQSDFCPTLIFLK
>CP029612.1|AWQ40156.1|1889282_1891706_-|DNA-translocase-FtsK
MAQKRSTNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLLFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPATPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>CP029612.1|AWQ40166.1|1902139_1903003_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFIAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWSGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDIYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYKDLEQLSVPTHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>CP029612.1|AWQ40167.1|1903087_1905169_-|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSISAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>CP029612.1|AWQ40168.1|1905299_1905665_-|DUF1033-domain-containing-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>CP029612.1|AWQ40169.1|1905762_1906332_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIVSLEVAG
>CP029612.1|AWQ40170.1|1906464_1906980_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQLLAKAKFEFLY
>CP029612.1|AWQ40171.1|1906996_1908235_+|MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDA
>CP029612.1|AWQ40172.1|1908208_1908358_-|hypothetical-protein
MLVIKPVSIRFSFLFYMPIFFKIRKREKLKIQIVDNFSVYNLGIIFLFF
>CP029612.1|AWQ40173.1|1908414_1909539_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>CP029612.1|AWQ40174.1|1909764_1910109_-|cysteine-desulfurase
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>CP029612.1|AWQ40175.1|1910176_1911322_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQMIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK

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Crispr_ID: CP029612_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029612_2

2182136-2182249

Orphan

Consensus_repeat	Method
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029612_2

>merge|CP029612|2|2182136-2182249|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTCCACATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAGACAACGTTCCCTTTGGTCACCTTGTACTGTTC

>CP029612|2|2|2182136-2182249|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC	CACATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAG
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC

Protein	Signature genes	Signature genes Name	Protein_function
CP029612.1\|AWQ40421.1\|2189074_2189251_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
CP029612.1\|AWQ40416.1\|2184351_2184759_-\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
CP029612.1\|AWQ40406.1\|2176312_2177089_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
CP029612.1\|AWQ40407.1\|2177195_2177471_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
CP029612.1\|AWQ40408.1\|2177454_2177592_-\|DNA-binding-protein	unknown	unknown	unknown
CP029612.1\|AWQ40418.1\|2185215_2187414_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
CP029612.1\|AWQ40417.1\|2184736_2185216_-\|endoribonuclease-YbeY	unknown	unknown	gnl\|CDD\|234575
CP029612.1\|AWQ40414.1\|2182564_2183353_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
CP029612.1\|AWQ40415.1\|2183435_2184338_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
CP029612.1\|AWQ40410.1\|2178603_2178795_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
CP029612.1\|AWQ40405.1\|2175855_2176293_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
CP029612.1\|AWQ40412.1\|2180920_2181829_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
CP029612.1\|AWQ40411.1\|2178834_2180919_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
CP029612.1\|AWQ40403.1\|2173899_2174781_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
CP029612.1\|AWQ40409.1\|2177637_2178570_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
CP029612.1\|AWQ40423.1\|2189981_2190812_+\|phosphoenolpyruvate-synthase-regulatory-protein	unknown	unknown	gnl\|CDD\|377080
CP029612.1\|AWQ40419.1\|2187442_2188417_-\|phosphate-starvation-inducible-protein-PhoH	unknown	unknown	gnl\|CDD\|224616
CP029612.1\|AWQ40404.1\|2174886_2175672_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
CP029612.1\|AWQ40422.1\|2189416_2189851_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
CP029612.1\|AWQ40420.1\|2188599_2189049_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480

Protein	Function_ID	Function_description	E-value
CP029612.1\|AWQ40421.1\|2189074_2189251_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
CP029612.1\|AWQ40416.1\|2184351_2184759_-\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	2.85033e-42
CP029612.1\|AWQ40406.1\|2176312_2177089_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.51292e-71
CP029612.1\|AWQ40407.1\|2177195_2177471_+\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.58992e-26
CP029612.1\|AWQ40418.1\|2185215_2187414_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	1.80428e-158
CP029612.1\|AWQ40417.1\|2184736_2185216_-\|endoribonuclease-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	8.00786e-61
CP029612.1\|AWQ40415.1\|2183435_2184338_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	4.35298e-180
CP029612.1\|AWQ40414.1\|2182564_2183353_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	6.18949e-71
CP029612.1\|AWQ40410.1\|2178603_2178795_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	6.66934e-06
CP029612.1\|AWQ40405.1\|2175855_2176293_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.03251e-32
CP029612.1\|AWQ40412.1\|2180920_2181829_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
CP029612.1\|AWQ40411.1\|2178834_2180919_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
CP029612.1\|AWQ40403.1\|2173899_2174781_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
CP029612.1\|AWQ40409.1\|2177637_2178570_+\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.42463e-134
CP029612.1\|AWQ40423.1\|2189981_2190812_+\|phosphoenolpyruvate-synthase-regulatory-protein	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	3.91447e-139
CP029612.1\|AWQ40419.1\|2187442_2188417_-\|phosphate-starvation-inducible-protein-PhoH	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.35931e-144
CP029612.1\|AWQ40404.1\|2174886_2175672_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	8.65565e-166
CP029612.1\|AWQ40422.1\|2189416_2189851_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	8.2692e-35
CP029612.1\|AWQ40420.1\|2188599_2189049_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63

>CP029612.1|AWQ40412.1|2180920_2181829_-|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>CP029612.1|AWQ40411.1|2178834_2180919_-|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFKVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>CP029612.1|AWQ40410.1|2178603_2178795_-|hypothetical-protein
MLETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>CP029612.1|AWQ40409.1|2177637_2178570_+|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQKIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>CP029612.1|AWQ40408.1|2177454_2177592_-|DNA-binding-protein
MKQRSFSIKIEKKLLQKSIKSRNYLLFKASSQRNQSLESKFIESL
>CP029612.1|AWQ40407.1|2177195_2177471_+|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>CP029612.1|AWQ40406.1|2176312_2177089_-|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLIEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>CP029612.1|AWQ40405.1|2175855_2176293_-|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEGQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDLLSLAVYRKNQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>CP029612.1|AWQ40404.1|2174886_2175672_-|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGIFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>CP029612.1|AWQ40403.1|2173899_2174781_-|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>CP029612.1|AWQ40414.1|2182564_2183353_-|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSKYSGVLCEKHWHLDEQRYHADPRAIHFIRLFAQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEK
>CP029612.1|AWQ40415.1|2183435_2184338_-|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSTDQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>CP029612.1|AWQ40416.1|2184351_2184759_-|diacylglycerol-kinase-family-protein
MRMALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>CP029612.1|AWQ40417.1|2184736_2185216_-|endoribonuclease-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGENELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>CP029612.1|AWQ40418.1|2185215_2187414_-|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVAFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICASAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>CP029612.1|AWQ40419.1|2187442_2188417_-|phosphate-starvation-inducible-protein-PhoH
MTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>CP029612.1|AWQ40420.1|2188599_2189049_-|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>CP029612.1|AWQ40421.1|2189074_2189251_-|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>CP029612.1|AWQ40422.1|2189416_2189851_-|transcriptional-repressor
MAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>CP029612.1|AWQ40423.1|2189981_2190812_+|phosphoenolpyruvate-synthase-regulatory-protein
MTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029612_1	1.2\|1901785\|30\|CP029612\|CRISPRCasFinder,PILER-CR	1901785-1901814	30	CP029612.1	868846-868875	0	1.0

1. spacer 1.2|1901785|30|CP029612|CRISPRCasFinder,PILER-CR matches to position: 868846-868875, mismatch: 0, identity: 1.0

aacgtttttagggatccaaatacctttaaa	CRISPR spacer
aacgtttttagggatccaaatacctttaaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029612_1	1.1\|1901719\|30\|CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	48974-49003	2	0.933
CP029612_1	1.1\|1901719\|30\|CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP042215	Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence	5329-5358	2	0.933
CP029612_1	1.1\|1901719\|30\|CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	37424-37453	2	0.933
CP029612_1	1.1\|1901719\|30\|CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP046125	Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence	26283-26312	2	0.933
CP029612_3	3.1\|2703918\|29\|CP029612\|CRISPRCasFinder	2703918-2703946	29	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	652952-652980	7	0.759
CP029612_1	1.1\|1901719\|30\|CP029612\|CRISPRCasFinder	1901719-1901748	30	MN855818	Myoviridae sp. isolate 237, complete genome	9541-9570	8	0.733
CP029612_1	1.3\|1901851\|30\|CP029612\|CRISPRCasFinder,PILER-CR	1901851-1901880	30	NZ_CP049038	Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_1, complete sequence	145993-146022	8	0.733

1. spacer 1.1|1901719|30|CP029612|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aattccgagtgattcacttttagcctgttc	Protospacer
.***********************.*****

2. spacer 1.1|1901719|30|CP029612|CRISPRCasFinder matches to NZ_CP042215 (Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aattccgagtgattcacttttagcctgttc	Protospacer
.***********************.*****

3. spacer 1.1|1901719|30|CP029612|CRISPRCasFinder matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
gattccgagtgattcgcttttagcctgttc	Protospacer
***************.********.*****

4. spacer 1.1|1901719|30|CP029612|CRISPRCasFinder matches to NZ_CP046125 (Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
gattcctagtgattcacttttagcctgttc	Protospacer
****** *****************.*****

5. spacer 3.1|2703918|29|CP029612|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 7, identity: 0.759

taggtgtt------ggttctggcgttggacccgga	CRISPR spacer
------ttccgcaaggttctggcgctggacccgga	Protospacer
      **      **********.**********

6. spacer 1.1|1901719|30|CP029612|CRISPRCasFinder matches to MN855818 (Myoviridae sp. isolate 237, complete genome) position: , mismatch: 8, identity: 0.733

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aggtccgagtaaatcacttttagctttagc	Protospacer
.. *******.* *************   *

7. spacer 1.3|1901851|30|CP029612|CRISPRCasFinder,PILER-CR matches to NZ_CP049038 (Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_1, complete sequence) position: , mismatch: 8, identity: 0.733

agagacagcgggaaaactacgatattcatc	CRISPR spacer
aagcagttcgggaaaaccacgatattcatt	Protospacer
*.. *   *********.***********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

839307 : 881458

Enterococcus_phage(40.74%)

tRNA,integrase,transposase,terminase,head,portal

attL 849994:850009|attR 874158:874173

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ39125.1\|839307_842088_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	8.6e-92	27.8
AWQ39126.1\|842139_843663_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.6e-76	33.7
AWQ39127.1\|843662_844331_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
AWQ39128.1\|844502_844871_-	DUF4828 domain-containing protein	NA	NA	NA	NA
AWQ39129.1\|845069_845801_+	DNA/RNA nuclease SfsA	NA	NA	NA	NA
AWQ39130.1\|845906_846905_+	gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
AWQ39131.1\|846931_848233_+	ATP-dependent helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.6e-40	32.6
AWQ39132.1\|848277_850983_+	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
849994:850009	attL	NA	NA	NA	NA
AWQ39133.1\|851211_851529_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
AWQ39134.1\|853181_853400_+	hypothetical protein	NA	NA	NA	NA
AWQ39135.1\|853419_853614_+	DUF3188 domain-containing protein	NA	NA	NA	NA
AWQ39136.1\|853613_854024_+	DUF3284 domain-containing protein	NA	NA	NA	NA
AWQ39137.1\|854299_854626_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
AWQ39138.1\|854648_854969_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
AWQ39139.1\|855034_856312_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AWQ39140.1\|856395_857790_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
AWQ39141.1\|857847_859041_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWQ39142.1\|859123_859243_+	hypothetical protein	NA	NA	NA	NA
AWQ39143.1\|859505_860642_-\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	5.4e-93	46.5
AWQ39144.1\|860717_861047_-	hypothetical protein	NA	NA	NA	NA
AWQ39145.1\|861060_861795_-	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	3.2e-22	51.0
AWQ39146.1\|861816_862455_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
AWQ39147.1\|862469_862811_-	XRE family transcriptional regulator	A0A141DZM2	Streptococcus_phage	7.2e-17	44.7
AWQ39148.1\|863131_863308_+	XRE family transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
AWQ39149.1\|863321_863660_+	DUF771 domain-containing protein	NA	NA	NA	NA
AWQ39150.1\|863717_863999_+	hypothetical protein	NA	NA	NA	NA
AWQ39151.1\|864398_865109_+	phage regulatory protein	D2IYT0	Enterococcus_phage	1.2e-122	95.7
AWQ39152.1\|865119_865305_+	hypothetical protein	D2IZW5	Enterococcus_phage	1.4e-19	88.3
AWQ39153.1\|865297_865516_+	hypothetical protein	D2J031	Enterococcus_phage	2.1e-09	49.2
AWQ39154.1\|865832_866024_-	DUF1508 domain-containing protein	NA	NA	NA	NA
AWQ39155.1\|866183_866486_+	hypothetical protein	NA	NA	NA	NA
AWQ39156.1\|866676_867156_+	hypothetical protein	E5DV79	Deep-sea_thermophilic_phage	1.2e-33	48.4
AWQ39157.1\|867167_868184_+	hypothetical protein	A0A0S2SY47	Bacillus_phage	9.2e-60	43.2
AWQ39158.1\|868188_868830_+	hypothetical protein	U5U4M2	Lactobacillus_phage	9.7e-31	36.0
AWQ39159.1\|868833_869631_+	helix-turn-helix domain-containing protein	A0A2D1GQ66	Lysinibacillus_phage	2.7e-22	54.4
AWQ39160.1\|869635_870163_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	4.5e-42	54.9
AWQ39161.1\|870175_870505_+	hypothetical protein	NA	NA	NA	NA
AWQ39162.1\|870524_870731_+	hypothetical protein	A0A1B1V001	Enterococcus_phage	2.8e-24	96.8
AWQ41356.1\|870783_871437_+	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
AWQ39163.1\|871433_872378_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.8e-102	59.3
AWQ39164.1\|872390_872963_+	hypothetical protein	A8ATD7	Listeria_phage	1.3e-23	33.1
AWQ41357.1\|872946_873333_+	hypothetical protein	D2IZL0	Enterococcus_phage	3.3e-18	43.9
AWQ39165.1\|873329_873668_+	hypothetical protein	S6CQM6	Streptococcus_phage	2.5e-14	44.1
AWQ39166.1\|873667_873907_+	hypothetical protein	NA	NA	NA	NA
AWQ39167.1\|873906_874155_+	hypothetical protein	NA	NA	NA	NA
AWQ39168.1\|874166_874700_+	DUF1642 domain-containing protein	D2IZZ0	Enterococcus_phage	5.8e-13	33.0
874158:874173	attR	NA	NA	NA	NA
AWQ39169.1\|874861_875074_+	hypothetical protein	D2IZL5	Enterococcus_phage	4.3e-28	87.7
AWQ39170.1\|875074_875494_+	transcriptional regulator	NA	NA	NA	NA
AWQ39171.1\|875741_876386_+	hypothetical protein	NA	NA	NA	NA
AWQ39172.1\|876452_876914_+\|transposase	transposase	D2IZL8	Enterococcus_phage	8.7e-58	74.8
AWQ39173.1\|876906_878295_+\|terminase	terminase	Q9AZ66	Lactococcus_phage	5.3e-175	67.0
AWQ39174.1\|878307_879783_+\|portal	phage portal protein	A0A0A7AQF2	Bacillus_phage	1.7e-30	25.8
AWQ39175.1\|879757_880798_+\|head	phage head morphogenesis protein	NA	NA	NA	NA
AWQ39176.1\|880806_881127_+	hypothetical protein	NA	NA	NA	NA
AWQ41358.1\|881194_881458_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	2.9e-42	95.4

DBSCAN-SWA_2

884896 : 916034

Lactococcus_phage(27.27%)

transposase,holin,tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ39184.1\|884896_885739_+\|tail	phage tail protein	A5GYM0	Lactococcus_phage	5.5e-10	53.9
AWQ39185.1\|885792_886143_+	hypothetical protein	A0A2H4JAA8	uncultured_Caudovirales_phage	4.1e-07	37.0
AWQ39186.1\|886364_889310_+\|tail	tail tape measure protein	D7RWD8	Brochothrix_phage	4.1e-76	42.8
AWQ39187.1\|889299_890034_+\|tail	phage tail protein	B8R658	Lactobacillus_phage	4.5e-16	31.9
AWQ39188.1\|890030_892730_+	hypothetical protein	Q9AZX5	Lactococcus_phage	8.4e-177	38.2
AWQ39189.1\|892744_893653_+\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.4e-11	26.7
AWQ39190.1\|893645_893963_+	hypothetical protein	NA	NA	NA	NA
AWQ39191.1\|893955_894273_+	hypothetical protein	NA	NA	NA	NA
AWQ39192.1\|894272_894824_+	hypothetical protein	NA	NA	NA	NA
AWQ39193.1\|894838_895213_+	hypothetical protein	NA	NA	NA	NA
AWQ39194.1\|895212_895350_+	XkdX family protein	NA	NA	NA	NA
AWQ39195.1\|895384_895618_+\|holin	holin	D2J075	Enterococcus_phage	7.0e-24	70.2
AWQ39196.1\|895620_895824_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	98.5
AWQ39197.1\|895828_896914_+	N-acetylmuramoyl-L-alanine amidase	A0A1D3SNQ1	Enterococcus_phage	1.1e-87	50.7
AWQ39198.1\|897308_897842_+	hypothetical protein	NA	NA	NA	NA
AWQ39199.1\|898060_898546_+	hypothetical protein	NA	NA	NA	NA
AWQ39200.1\|898712_899045_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AWQ39201.1\|899158_901804_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	3.3e-85	39.9
AWQ39202.1\|901973_902603_+	transcriptional regulator	NA	NA	NA	NA
AWQ39203.1\|902615_903428_+	phosphoenolpyruvate synthase regulatory protein	NA	NA	NA	NA
AWQ39204.1\|903498_906030_-	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
AWQ39205.1\|906026_906761_-	alpha/beta hydrolase	NA	NA	NA	NA
AWQ39206.1\|906937_907522_+	hypothetical protein	NA	NA	NA	NA
AWQ39207.1\|907544_908600_+	endonuclease	NA	NA	NA	NA
AWQ39208.1\|908648_910886_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.1e-120	30.9
AWQ41359.1\|911119_913336_+	6-aminohexanoate hydrolase	NA	NA	NA	NA
AWQ39209.1\|913427_914357_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
AWQ39210.1\|914399_915053_+	DUF4767 domain-containing protein	NA	NA	NA	NA
AWQ39211.1\|915074_916034_-\|transposase	IS30 family transposase IS6770	NA	NA	NA	NA

DBSCAN-SWA_3

987452 : 1047269

Enterococcus_phage(25.71%)

holin,tRNA,integrase,terminase,protease,tail,capsid,head,portal

attL 981913:981929|attR 1036128:1036144

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
981913:981929	attL	NA	NA	NA	NA
AWQ41365.1\|987452_988583_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	2.7e-100	50.4
AWQ41366.1\|988666_989572_-	DUF4352 domain-containing protein	NA	NA	NA	NA
AWQ39270.1\|989665_990088_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
AWQ39271.1\|990088_990430_-	XRE family transcriptional regulator	A0A141DZM2	Streptococcus_phage	2.8e-21	46.7
AWQ39272.1\|990719_990911_+	hypothetical protein	NA	NA	NA	NA
AWQ39273.1\|990923_991253_+	DUF771 domain-containing protein	NA	NA	NA	NA
AWQ39274.1\|991260_991449_+	hypothetical protein	A0A0S2MY96	Enterococcus_phage	2.7e-18	80.7
AWQ39275.1\|991515_991815_+	hypothetical protein	NA	NA	NA	NA
AWQ39276.1\|991811_992036_+	hypothetical protein	D2IZX4	Enterococcus_phage	2.2e-22	69.9
AWQ39277.1\|992038_992395_+	hypothetical protein	NA	NA	NA	NA
AWQ41367.1\|992381_992489_+	hypothetical protein	D2IZX5	Enterococcus_phage	8.8e-06	89.7
AWQ39278.1\|992485_993451_+	RecT protein	A0A1X9I5N6	Streptococcus_phage	1.2e-77	62.6
AWQ41368.1\|993425_994229_+	hypothetical protein	J7KGZ1	Streptococcus_phage	3.0e-61	50.6
AWQ39279.1\|994243_995023_+	DnaD domain protein	B4XYS6	Lactobacillus_phage	2.3e-42	63.4
AWQ39280.1\|995034_995874_+	ATP-binding protein	U5PVD6	Bacillus_phage	4.5e-20	32.1
AWQ39281.1\|996011_996281_+	hypothetical protein	NA	NA	NA	NA
AWQ39282.1\|996429_996894_+	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	1.7e-32	48.3
AWQ39283.1\|996913_997519_+	hypothetical protein	NA	NA	NA	NA
AWQ39284.1\|997534_997741_+	hypothetical protein	A0A1B1V001	Enterococcus_phage	1.3e-24	96.8
AWQ39285.1\|997826_998075_-	hypothetical protein	NA	NA	NA	NA
AWQ39286.1\|998403_998871_+	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	2.9e-08	27.8
AWQ39287.1\|999177_999684_-	hypothetical protein	NA	NA	NA	NA
AWQ39288.1\|1000211_1000481_+	hypothetical protein	NA	NA	NA	NA
AWQ39289.1\|1000541_1000856_+	hypothetical protein	NA	NA	NA	NA
AWQ39290.1\|1000848_1001160_+	HNH endonuclease	A0A1S5SFB3	Streptococcus_phage	4.0e-30	64.1
AWQ39291.1\|1001443_1001752_+\|terminase	terminase	D2XR14	Bacillus_phage	3.2e-16	50.0
AWQ39292.1\|1001748_1003431_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	8.0e-226	69.4
AWQ39293.1\|1003464_1003632_-	YjzC family protein	A0A0A7RTS6	Clostridium_phage	4.0e-13	74.0
AWQ39294.1\|1003919_1004102_+	hypothetical protein	NA	NA	NA	NA
AWQ39295.1\|1004134_1005298_+\|portal	phage portal protein	A0A059T6F0	Listeria_phage	1.8e-75	39.5
AWQ39296.1\|1005284_1006004_+\|protease	Clp protease ClpP	A0A2H4J8Y7	uncultured_Caudovirales_phage	2.7e-42	45.0
AWQ39297.1\|1006000_1007188_+\|capsid	phage major capsid protein	D2XR18	Bacillus_phage	7.2e-64	37.1
AWQ39298.1\|1007264_1007546_+	hypothetical protein	A0A2H4JAM0	uncultured_Caudovirales_phage	1.8e-13	48.8
AWQ39299.1\|1007520_1007907_+\|head,tail	phage head-tail adapter protein	A8ATA1	Listeria_phage	3.8e-30	54.3
AWQ39300.1\|1007903_1008308_+	hypothetical protein	A0A2P0ZLD7	Lactobacillus_phage	2.0e-18	42.6
AWQ39301.1\|1008304_1008700_+	hypothetical protein	A0A059T681	Listeria_phage	1.5e-18	46.3
AWQ39302.1\|1008732_1009326_+\|tail	phage tail protein	A0A060AKE9	Staphylococcus_phage	2.6e-22	35.1
AWQ39303.1\|1009399_1009873_+\|tail	phage tail protein	A0A1D6Z291	Staphylococcus_phage	3.9e-21	45.6
AWQ39304.1\|1009929_1010277_+	hypothetical protein	NA	NA	NA	NA
AWQ39305.1\|1010498_1015250_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.6e-13	42.2
AWQ39306.1\|1015249_1016149_+\|tail	phage tail family protein	D2J071	Enterococcus_phage	2.9e-49	37.4
AWQ39307.1\|1016151_1017276_+	hypothetical protein	Q77MU2	Lactococcus_phage	2.6e-87	45.0
AWQ39308.1\|1017286_1018342_+	structural protein	D2J073	Enterococcus_phage	9.0e-50	37.0
AWQ39309.1\|1018353_1019142_+	hypothetical protein	D2IYX9	Enterococcus_phage	3.3e-41	71.6
AWQ39310.1\|1019177_1019576_+\|holin	holin	F0PIJ6	Enterococcus_phage	1.6e-36	54.2
AWQ39311.1\|1019630_1020890_+	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	6.6e-225	91.6
AWQ39312.1\|1021167_1021776_+	hypothetical protein	NA	NA	NA	NA
AWQ39313.1\|1021777_1022083_+	hypothetical protein	NA	NA	NA	NA
AWQ39314.1\|1022084_1022552_+	hypothetical protein	NA	NA	NA	NA
AWQ39315.1\|1022799_1023285_+	hypothetical protein	NA	NA	NA	NA
AWQ39316.1\|1024026_1024332_-	DUF898 domain-containing protein	NA	NA	NA	NA
AWQ39317.1\|1024666_1026268_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
AWQ39318.1\|1026392_1027988_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.7e-21	26.3
AWQ39319.1\|1028057_1028792_+	methyltransferase domain-containing protein	NA	NA	NA	NA
AWQ39320.1\|1028788_1029190_-	DUF1093 domain-containing protein	NA	NA	NA	NA
AWQ39321.1\|1029298_1030651_-	amino acid permease	NA	NA	NA	NA
AWQ39322.1\|1030821_1031007_-	hypothetical protein	NA	NA	NA	NA
AWQ39323.1\|1031187_1031493_-	hypothetical protein	NA	NA	NA	NA
AWQ39324.1\|1031495_1031624_+	hypothetical protein	NA	NA	NA	NA
AWQ39325.1\|1031843_1032605_+	(Fe-S)-binding protein	NA	NA	NA	NA
AWQ39326.1\|1032617_1034090_+	iron-sulfur cluster-binding protein	NA	NA	NA	NA
AWQ39327.1\|1034082_1034802_+	lactate utilization protein C	NA	NA	NA	NA
AWQ39328.1\|1035022_1035571_+	signal peptidase I	NA	NA	NA	NA
AWQ39329.1\|1035681_1039272_+	ATP-dependent helicase	NA	NA	NA	NA
1036128:1036144	attR	NA	NA	NA	NA
AWQ39330.1\|1039264_1043059_+	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	1.7e-18	23.0
AWQ39331.1\|1043128_1043473_+	transcriptional regulator	NA	NA	NA	NA
AWQ39332.1\|1043791_1044838_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	4.6e-30	33.9
AWQ39333.1\|1044845_1047269_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_4

1199404 : 1217175

Enterococcus_phage(42.86%)

holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ39487.1\|1199404_1201801_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.3e-19	24.2
AWQ39488.1\|1201825_1202176_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
AWQ39489.1\|1202258_1202489_+	hypothetical protein	NA	NA	NA	NA
AWQ39490.1\|1202548_1203022_-	toxin	A0A097BY56	Enterococcus_phage	1.1e-60	71.2
AWQ39491.1\|1203068_1203551_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
AWQ39492.1\|1203719_1203902_+	hypothetical protein	NA	NA	NA	NA
AWQ39493.1\|1203932_1204703_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	2.5e-33	57.0
AWQ39494.1\|1204721_1205564_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.3e-30	30.7
AWQ39495.1\|1205566_1205659_+	hypothetical protein	NA	NA	NA	NA
AWQ39496.1\|1205651_1206023_+	hypothetical protein	NA	NA	NA	NA
AWQ39497.1\|1206042_1206450_+	transcriptional regulator	NA	NA	NA	NA
AWQ39498.1\|1206694_1207087_+	hypothetical protein	NA	NA	NA	NA
AWQ39499.1\|1207099_1207612_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
AWQ39500.1\|1207644_1208004_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
AWQ39501.1\|1208021_1208390_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	1.7e-08	33.3
AWQ39502.1\|1208379_1211313_+	hypothetical protein	A0A1U9WR55	Streptococcus_virus	1.1e-09	25.0
AWQ39503.1\|1211314_1212241_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
AWQ39504.1\|1212253_1213711_+	hypothetical protein	C9E2K6	Enterococcus_phage	4.7e-174	47.5
AWQ39505.1\|1213743_1215513_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.7e-141	63.6
AWQ39506.1\|1215536_1215932_+\|holin	holin	F0PIJ6	Enterococcus_phage	1.7e-33	48.9
AWQ39507.1\|1216077_1217175_+	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	6.9e-77	44.3

DBSCAN-SWA_5

1349112 : 1405451

Listeria_phage(49.02%)

terminase,head,integrase,tail

attL 1349067:1349089|attR 1409156:1409178

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1349067:1349089	attL	NA	NA	NA	NA
AWQ39622.1\|1349112_1350339_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.5e-76	41.9
AWQ39623.1\|1350338_1350620_-	hypothetical protein	NA	NA	NA	NA
AWQ39624.1\|1350775_1351369_-	hypothetical protein	D2J022	Enterococcus_phage	8.1e-24	55.3
AWQ39625.1\|1351427_1352180_-	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	5.7e-06	35.6
AWQ39626.1\|1352197_1352662_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	1.5e-20	36.6
AWQ39627.1\|1352682_1353006_-	XRE family transcriptional regulator	A8ATJ9	Listeria_phage	2.3e-17	66.7
AWQ39628.1\|1353171_1353363_+	XRE family transcriptional regulator	A8ATK0	Listeria_phage	5.6e-11	58.3
AWQ39629.1\|1353402_1353549_+	hypothetical protein	NA	NA	NA	NA
AWQ39630.1\|1353611_1354172_+	hypothetical protein	NA	NA	NA	NA
AWQ39631.1\|1354152_1354383_+	DNA-binding protein	NA	NA	NA	NA
AWQ39632.1\|1354394_1354562_+	hypothetical protein	NA	NA	NA	NA
AWQ39633.1\|1354562_1354778_+	hypothetical protein	NA	NA	NA	NA
AWQ39634.1\|1354833_1355124_+	hypothetical protein	NA	NA	NA	NA
AWQ39635.1\|1355128_1357243_+	hypothetical protein	A0A1L2K2K3	Aeribacillus_phage	6.8e-49	25.4
AWQ39636.1\|1357243_1358416_+	hypothetical protein	NA	NA	NA	NA
AWQ39637.1\|1358415_1359117_+	MBL fold metallo-hydrolase	A0A1L2JY21	Aeribacillus_phage	6.0e-50	42.7
AWQ39638.1\|1359128_1359893_+	DnaD domain protein	A0A1B0Y2R2	Lactobacillus_phage	7.5e-14	61.4
AWQ39639.1\|1359905_1360406_+	recombinase RecU	A0A1L2JY30	Aeribacillus_phage	8.4e-14	35.4
AWQ39640.1\|1360426_1360741_+	hypothetical protein	NA	NA	NA	NA
AWQ39641.1\|1360824_1361574_+	hypothetical protein	D2IZY3	Enterococcus_phage	8.7e-116	84.5
AWQ39642.1\|1361598_1361793_+	hypothetical protein	NA	NA	NA	NA
AWQ39643.1\|1361823_1362051_+	hypothetical protein	C9E2N4	Enterococcus_phage	1.0e-06	50.9
AWQ39644.1\|1362109_1362850_+	DNA methyltransferase	U4KJA1	Streptococcus_phage	2.5e-99	69.0
AWQ41375.1\|1362906_1363560_+	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
AWQ39645.1\|1363556_1364501_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.8e-102	59.3
AWQ39646.1\|1364513_1365086_+	hypothetical protein	A8ATD7	Listeria_phage	1.3e-23	33.1
AWQ41376.1\|1365069_1365456_+	hypothetical protein	D2IZL0	Enterococcus_phage	3.3e-18	43.9
AWQ39647.1\|1365452_1365791_+	hypothetical protein	S6CQM6	Streptococcus_phage	2.5e-14	44.1
AWQ39648.1\|1365790_1366030_+	hypothetical protein	NA	NA	NA	NA
AWQ39649.1\|1366029_1366278_+	hypothetical protein	NA	NA	NA	NA
AWQ39650.1\|1366289_1366823_+	DUF1642 domain-containing protein	D2IZZ0	Enterococcus_phage	5.8e-13	33.0
AWQ39651.1\|1366984_1367197_+	hypothetical protein	D2IZL5	Enterococcus_phage	1.1e-28	87.9
AWQ39652.1\|1367189_1367282_+	hypothetical protein	NA	NA	NA	NA
AWQ39653.1\|1367297_1367477_+	hypothetical protein	NA	NA	NA	NA
AWQ39654.1\|1367577_1368162_+	positive control factor	NA	NA	NA	NA
AWQ39655.1\|1368596_1368800_+	hypothetical protein	NA	NA	NA	NA
AWQ39656.1\|1368901_1369171_+	hypothetical protein	NA	NA	NA	NA
AWQ41377.1\|1370350_1370581_+	hypothetical protein	A8ATN7	Listeria_phage	2.3e-11	52.3
AWQ39657.1\|1370595_1371321_+\|terminase	terminase small subunit	NA	NA	NA	NA
AWQ39658.1\|1371301_1372738_+	hypothetical protein	A5GYP8	Lactococcus_phage	3.8e-200	72.4
AWQ39659.1\|1372760_1374155_+	DUF1073 domain-containing protein	A8ATG1	Listeria_phage	8.0e-147	56.4
AWQ39660.1\|1374144_1375389_+\|head	phage head morphogenesis protein	A8ATG2	Listeria_phage	2.1e-53	41.6
AWQ39661.1\|1375381_1375546_+	hypothetical protein	NA	NA	NA	NA
AWQ39662.1\|1375602_1375890_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.7e-27	68.3
AWQ39663.1\|1375882_1376092_+	LysM domain-containing protein	NA	NA	NA	NA
AWQ39664.1\|1376104_1377208_+	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	1.7e-88	50.6
AWQ39665.1\|1377210_1377681_+	hypothetical protein	NA	NA	NA	NA
AWQ39666.1\|1377701_1378583_+	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	6.7e-83	52.2
AWQ39667.1\|1378602_1378989_+	hypothetical protein	NA	NA	NA	NA
AWQ39668.1\|1379000_1379342_+	DUF4054 domain-containing protein	NA	NA	NA	NA
AWQ39669.1\|1379338_1379944_+	hypothetical protein	A8ATG9	Listeria_phage	5.2e-34	42.1
AWQ39670.1\|1379943_1380303_+	hypothetical protein	A0A2H4JDP3	uncultured_Caudovirales_phage	2.3e-13	43.7
AWQ39671.1\|1380289_1380766_+	hypothetical protein	A8ATH1	Listeria_phage	7.2e-23	42.8
AWQ39672.1\|1380762_1381800_+	DUF3383 domain-containing protein	A8ATH2	Listeria_phage	8.4e-101	56.4
AWQ39673.1\|1381815_1382214_+	hypothetical protein	A8ATH3	Listeria_phage	6.6e-30	54.0
AWQ39674.1\|1382266_1382599_+	hypothetical protein	A8ATH4	Listeria_phage	6.3e-26	57.8
AWQ39675.1\|1382579_1382780_+	hypothetical protein	A8ATH5	Listeria_phage	6.9e-12	62.1
AWQ39676.1\|1382782_1387966_+	peptidase M23	A8ATH6	Listeria_phage	4.7e-152	43.1
AWQ39677.1\|1387965_1388523_+	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	2.8e-34	43.2
AWQ39678.1\|1388532_1388895_+	hypothetical protein	A8ATH8	Listeria_phage	1.1e-28	45.8
AWQ39679.1\|1388895_1389726_+	hypothetical protein	A8ATH9	Listeria_phage	7.8e-65	45.8
AWQ39680.1\|1389725_1390058_+	hypothetical protein	A8ATI0	Listeria_phage	1.6e-21	50.0
AWQ39681.1\|1390057_1390405_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
AWQ39682.1\|1390397_1391552_+	hypothetical protein	A8ATI2	Listeria_phage	4.3e-114	54.1
AWQ39683.1\|1391535_1392165_+	hypothetical protein	A8ATI3	Listeria_phage	4.1e-58	57.4
AWQ39684.1\|1392177_1393653_+\|tail	phage tail protein	D2J018	Enterococcus_phage	4.3e-58	61.3
AWQ39685.1\|1393687_1394122_+	hypothetical protein	NA	NA	NA	NA
AWQ39686.1\|1394121_1394250_+	XkdX family protein	NA	NA	NA	NA
AWQ39687.1\|1394254_1394611_+	hypothetical protein	NA	NA	NA	NA
AWQ39688.1\|1394607_1394805_+	hypothetical protein	NA	NA	NA	NA
AWQ39689.1\|1394862_1395948_+	N-acetylmuramoyl-L-alanine amidase	A0A1D3SNQ1	Enterococcus_phage	1.1e-87	50.7
AWQ39690.1\|1396342_1396876_+	hypothetical protein	NA	NA	NA	NA
AWQ39691.1\|1397015_1397264_-	hypothetical protein	A0A097BYB1	Enterococcus_phage	1.2e-34	91.5
AWQ39692.1\|1397674_1398901_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.5e-76	41.9
AWQ39693.1\|1398900_1399182_-	hypothetical protein	NA	NA	NA	NA
AWQ39694.1\|1399337_1399931_-	hypothetical protein	D2J022	Enterococcus_phage	8.1e-24	55.3
AWQ39695.1\|1401855_1402203_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
AWQ39696.1\|1402195_1403350_+	hypothetical protein	A8ATI2	Listeria_phage	4.3e-114	54.1
AWQ39697.1\|1403333_1403963_+	hypothetical protein	A8ATI3	Listeria_phage	4.1e-58	57.4
AWQ39698.1\|1403975_1405451_+\|tail	phage tail protein	D2J018	Enterococcus_phage	4.3e-58	61.3
1409156:1409178	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1695822 : 1704466

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ39979.1\|1695822_1696395_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.1
AWQ39980.1\|1696391_1697423_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.1e-55	44.4
AWQ39981.1\|1697424_1698864_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.7e-49	32.1
AWQ39982.1\|1698839_1701059_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.8e-146	39.8
AWQ39983.1\|1701055_1701730_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AWQ39984.1\|1701730_1701982_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AWQ39985.1\|1701995_1702709_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
AWQ39986.1\|1702860_1703985_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
AWQ39987.1\|1703977_1704466_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	42.0

DBSCAN-SWA_7

1735454 : 1788514

Streptococcus_phage(52.94%)

transposase,protease,integrase

attL 1745989:1746004|attR 1751538:1751553

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40012.1\|1735454_1736309_-\|protease	serine protease	NA	NA	NA	NA
AWQ40013.1\|1736387_1737890_-	M4 family peptidase	NA	NA	NA	NA
AWQ40014.1\|1738124_1739468_-	GHKL domain-containing protein	NA	NA	NA	NA
AWQ40015.1\|1739464_1740193_-	protein FsrB	NA	NA	NA	NA
AWQ40016.1\|1740281_1741013_-	DNA-binding response regulator	NA	NA	NA	NA
AWQ40017.1\|1741431_1743414_-	CHAP domain-containing protein	Q332B8	Clostridium_botulinum_C_phage	3.1e-19	36.8
AWQ40018.1\|1745852_1746605_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
1745989:1746004	attL	NA	NA	NA	NA
AWQ40019.1\|1746940_1747933_-	DUF4767 domain-containing protein	NA	NA	NA	NA
AWQ40020.1\|1748023_1748608_-	HD domain-containing protein	NA	NA	NA	NA
AWQ40021.1\|1748825_1749731_+	polysaccharide deacetylase	NA	NA	NA	NA
AWQ41391.1\|1749760_1749856_+	hypothetical protein	NA	NA	NA	NA
AWQ40022.1\|1749997_1751176_-\|integrase	site-specific integrase	S6C485	Thermus_phage	3.4e-29	30.5
AWQ40023.1\|1751278_1751590_-	DNA-binding protein	NA	NA	NA	NA
1751538:1751553	attR	NA	NA	NA	NA
AWQ40024.1\|1751938_1752184_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWQ40025.1\|1752177_1752579_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AWQ40026.1\|1753146_1754982_-	beta-galactosidase	NA	NA	NA	NA
AWQ40027.1\|1755153_1756416_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
AWQ40028.1\|1756553_1756940_+	hypothetical protein	NA	NA	NA	NA
AWQ40029.1\|1757033_1758326_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.9e-31	40.4
AWQ40030.1\|1758599_1758860_-	hypothetical protein	NA	NA	NA	NA
AWQ41392.1\|1759464_1760626_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3
AWQ41393.1\|1760698_1760905_+	hypothetical protein	U5P429	Shigella_phage	2.0e-06	53.3
AWQ40031.1\|1760908_1761022_+	hypothetical protein	NA	NA	NA	NA
AWQ40032.1\|1761174_1761570_-	aspartate 1-decarboxylase	NA	NA	NA	NA
AWQ40033.1\|1761582_1762431_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
AWQ40034.1\|1762445_1763273_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	M4QNT1	Ostreococcus_lucimarinus_virus	5.4e-50	38.0
AWQ40035.1\|1763284_1764130_-	DUF2520 domain-containing protein	NA	NA	NA	NA
AWQ40036.1\|1765877_1767197_-	sensor histidine kinase	NA	NA	NA	NA
AWQ40037.1\|1767193_1767847_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	4.0e-24	33.2
AWQ40038.1\|1767908_1768049_-	RNA helicase	NA	NA	NA	NA
AWQ40039.1\|1769417_1770794_-	ABC transporter permease	NA	NA	NA	NA
AWQ40040.1\|1770793_1771450_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-22	32.1
AWQ40041.1\|1771459_1772737_-	ABC transporter permease	NA	NA	NA	NA
AWQ40042.1\|1772923_1773409_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
AWQ40043.1\|1773564_1773975_-	hypothetical protein	NA	NA	NA	NA
AWQ40044.1\|1774219_1774507_+	hypothetical protein	NA	NA	NA	NA
AWQ40045.1\|1774507_1774735_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AWQ40046.1\|1774805_1775996_+\|transposase	IS256 family transposase	NA	NA	NA	NA
AWQ40047.1\|1776100_1777012_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.3e-57	41.1
AWQ40048.1\|1777030_1778035_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	1.4e-121	66.3
AWQ40049.1\|1778031_1780155_-	FUSC family protein	A0A1S5SF30	Streptococcus_phage	2.4e-174	58.7
AWQ40050.1\|1780159_1782607_-	ATP/GTP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
AWQ41394.1\|1782593_1782983_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	66.7
AWQ40051.1\|1783046_1783775_+	hypothetical protein	NA	NA	NA	NA
AWQ40052.1\|1783781_1784609_-	hypothetical protein	NA	NA	NA	NA
AWQ40053.1\|1784682_1785186_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	3.1e-56	61.2
AWQ40054.1\|1785198_1785420_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
AWQ40055.1\|1785816_1787067_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
AWQ40056.1\|1787198_1787333_-	DUF3789 domain-containing protein	NA	NA	NA	NA
AWQ40057.1\|1787329_1788514_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	1.0e-142	62.1

DBSCAN-SWA_8

1919916 : 1938246

Enterococcus_phage(44.44%)

holin,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40184.1\|1919916_1920987_-	methionine import ATP-binding protein MetN 1	G9BWD6	Planktothrix_phage	4.0e-29	35.1
AWQ40185.1\|1921977_1922184_+	hypothetical protein	NA	NA	NA	NA
AWQ40186.1\|1922425_1922674_+	hypothetical protein	A0A097BYB1	Enterococcus_phage	6.1e-34	91.5
AWQ40187.1\|1922692_1923661_-\|protease	CAAX protease	A0A059NT88	Lactococcus_phage	1.3e-79	43.5
AWQ41399.1\|1924471_1925458_-	endolysin	F0PIJ7	Enterococcus_phage	4.7e-85	67.6
AWQ40188.1\|1925444_1925723_-\|holin	holin	NA	NA	NA	NA
AWQ40189.1\|1925722_1925977_-	hypothetical protein	NA	NA	NA	NA
AWQ40190.1\|1925989_1926409_-	XkdX family protein	F0PIJ5	Enterococcus_phage	1.1e-56	85.4
AWQ40191.1\|1926396_1927254_-	collagen-like protein	F0PIJ4	Enterococcus_phage	1.2e-60	87.3
AWQ40192.1\|1927243_1927732_-	hypothetical protein	A0A1W6JI16	Lactococcus_phage	8.4e-35	46.0
AWQ41400.1\|1927744_1928434_-	hypothetical protein	NA	NA	NA	NA
AWQ40193.1\|1928433_1931010_-	endolysin	A0A1B1IM47	Lactococcus_phage	1.3e-30	46.6
AWQ40194.1\|1931046_1931949_-	hypothetical protein	NA	NA	NA	NA
AWQ40195.1\|1931963_1933079_-	hypothetical protein	NA	NA	NA	NA
AWQ40196.1\|1933083_1938246_-\|tail	phage tail protein	A0A1P8VVL4	Streptococcus_phage	1.2e-35	30.1

DBSCAN-SWA_9

1949280 : 1962685

Enterococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40211.1\|1949280_1949700_-	hypothetical protein	A0A2H4J1L3	uncultured_Caudovirales_phage	4.7e-18	51.0
AWQ40212.1\|1949689_1950886_-	DNA modification methylase	Q708N6	Streptococcus_phage	1.8e-110	51.1
AWQ40213.1\|1951293_1951719_-	ArpU family transcriptional regulator	D2IYV6	Enterococcus_phage	9.9e-24	42.3
AWQ40214.1\|1951864_1951990_-	hypothetical protein	NA	NA	NA	NA
AWQ40215.1\|1952017_1952218_-	hypothetical protein	D2IYV2	Enterococcus_phage	2.9e-26	84.8
AWQ40216.1\|1952218_1952785_-	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	2.0e-40	49.0
AWQ40217.1\|1952941_1953301_-	DNA topoisomerase	NA	NA	NA	NA
AWQ40218.1\|1953297_1953732_-	hypothetical protein	A0A097BY34	Enterococcus_phage	7.2e-30	55.0
AWQ40219.1\|1953737_1953965_-	hypothetical protein	NA	NA	NA	NA
AWQ40220.1\|1953986_1954784_-	DNA adenine methylase	R4IBV6	Listeria_phage	2.2e-109	69.8
AWQ40221.1\|1955088_1955439_-	hypothetical protein	A0A2L0V129	Agrobacterium_phage	1.1e-12	41.6
AWQ40222.1\|1955450_1955783_-	hypothetical protein	A0A0S2MYB8	Enterococcus_phage	1.9e-22	59.7
AWQ40223.1\|1955779_1956205_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.5e-59	82.6
AWQ40224.1\|1956222_1956522_-	hypothetical protein	D2IZY1	Enterococcus_phage	6.0e-44	91.9
AWQ40225.1\|1956521_1957514_-	DUF4373 domain-containing protein	D2IYU0	Enterococcus_phage	2.4e-145	91.8
AWQ40226.1\|1957527_1958421_-	recombinase RecT	D2IYT9	Enterococcus_phage	1.1e-149	91.2
AWQ40227.1\|1958554_1959496_-	endonuclease	D2IZK1	Enterococcus_phage	4.0e-134	73.9
AWQ40228.1\|1959509_1959821_-	hypothetical protein	NA	NA	NA	NA
AWQ40229.1\|1959851_1960142_-	hypothetical protein	NA	NA	NA	NA
AWQ40230.1\|1960226_1960553_-	hypothetical protein	NA	NA	NA	NA
AWQ40231.1\|1960553_1960763_-	hypothetical protein	NA	NA	NA	NA
AWQ40232.1\|1960781_1960892_-	hypothetical protein	NA	NA	NA	NA
AWQ40233.1\|1960905_1961157_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWQ40234.1\|1961171_1961699_-	hypothetical protein	NA	NA	NA	NA
AWQ40235.1\|1961970_1962156_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWQ40236.1\|1962307_1962685_+	XRE family transcriptional regulator	A0A2P1JU09	Anoxybacillus_phage	5.9e-12	35.4

DBSCAN-SWA_10

2247090 : 2334915

103

Enterococcus_phage(37.74%)

tRNA,integrase,transposase,terminase,tail,head,portal

attL 2289162:2289183|attR 2331991:2332012

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40475.1\|2247090_2248137_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	4.4e-57	40.1
AWQ40476.1\|2248133_2248598_-	ribosomal-protein-alanine N-acetyltransferase	NA	NA	NA	NA
AWQ41409.1\|2248605_2249073_-	ribosomal-protein-alanine N-acetyltransferase	NA	NA	NA	NA
AWQ40477.1\|2249131_2249887_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
AWQ40478.1\|2249966_2252009_-	penicillin-binding protein	NA	NA	NA	NA
AWQ40479.1\|2252216_2253449_+	virion core protein	NA	NA	NA	NA
AWQ40480.1\|2253552_2254698_+	ATP-binding protein	NA	NA	NA	NA
AWQ40481.1\|2254694_2255504_+	TPM domain-containing protein	NA	NA	NA	NA
AWQ40482.1\|2255726_2256470_+	DUF3862 domain-containing protein	A9D9J1	Lactobacillus_prophage	1.5e-19	39.9
AWQ40483.1\|2256830_2257562_-	HAD family hydrolase	NA	NA	NA	NA
AWQ40484.1\|2257709_2257937_-	hypothetical protein	NA	NA	NA	NA
AWQ40485.1\|2258024_2258675_-	diphthine--ammonia ligase	NA	NA	NA	NA
AWQ40486.1\|2259337_2260150_-	ABC transporter permease	NA	NA	NA	NA
AWQ40487.1\|2260149_2261493_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
AWQ40488.1\|2261518_2262658_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	3.5e-140	64.7
AWQ40489.1\|2262716_2263115_-	lipoprotein	NA	NA	NA	NA
AWQ40490.1\|2263132_2265586_-	UDP-N-acetylenolpyruvoylglucosamine reductase	NA	NA	NA	NA
AWQ40491.1\|2265654_2268165_-	glycosyl transferase family 2	A0A1V0SAH6	Catovirus	3.5e-07	29.9
AWQ40492.1\|2268234_2269701_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
AWQ40493.1\|2269719_2270889_-	CDP-glycerol glycerophosphotransferase family protein	NA	NA	NA	NA
AWQ40494.1\|2271361_2272162_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
AWQ40495.1\|2272158_2272974_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	3.6e-22	42.4
AWQ40496.1\|2273321_2274140_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWQ40497.1\|2274154_2274841_-	ABC transporter permease	NA	NA	NA	NA
AWQ40498.1\|2274833_2275871_-	methionine import ATP-binding protein MetN 2	G3M9Y6	Bacillus_virus	7.8e-30	35.2
AWQ40499.1\|2275864_2276065_+	hypothetical protein	NA	NA	NA	NA
AWQ40500.1\|2276031_2276124_-	hypothetical protein	NA	NA	NA	NA
AWQ41410.1\|2276285_2276600_-	glycine cleavage system protein H	NA	NA	NA	NA
AWQ40501.1\|2276605_2276965_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.5e-30	56.9
AWQ40502.1\|2276989_2278177_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
AWQ40503.1\|2278420_2279857_-	hypothetical protein	NA	NA	NA	NA
AWQ40504.1\|2279857_2280559_-	hypothetical protein	NA	NA	NA	NA
AWQ40505.1\|2280757_2285713_-	DUF5011 domain-containing protein	NA	NA	NA	NA
AWQ40506.1\|2285888_2287220_-	hypothetical protein	NA	NA	NA	NA
AWQ40507.1\|2287332_2287884_-	XRE family transcriptional regulator	NA	NA	NA	NA
AWQ40508.1\|2288097_2288805_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
AWQ40509.1\|2288791_2289118_+	AzlD domain-containing protein	NA	NA	NA	NA
2289162:2289183	attL	NA	NA	NA	NA
AWQ40510.1\|2289221_2289797_+	hypothetical protein	NA	NA	NA	NA
AWQ40511.1\|2289855_2290959_-	N-acetylmuramoyl-L-alanine amidase	V5URN7	Enterococcus_phage	5.1e-88	49.3
AWQ40512.1\|2290999_2291209_-	hypothetical protein	A0A0S2MYG0	Enterococcus_phage	1.8e-15	60.6
AWQ40513.1\|2291214_2291340_-	XkdX family protein	NA	NA	NA	NA
AWQ40514.1\|2291339_2291774_-	hypothetical protein	NA	NA	NA	NA
AWQ41411.1\|2291792_2293262_-	hypothetical protein	D2J018	Enterococcus_phage	7.2e-106	71.6
AWQ40515.1\|2293320_2293929_-	DUF2313 domain-containing protein	Q20DB9	Lactobacillus_phage	4.3e-12	31.5
AWQ40516.1\|2293925_2295068_-\|tail	phage tail protein	Q708L2	Streptococcus_phage	6.9e-88	43.7
AWQ40517.1\|2295064_2295448_-	DUF2634 domain-containing protein	Q708L3	Streptococcus_phage	4.7e-25	51.6
AWQ40518.1\|2295451_2295754_-	DUF2577 domain-containing protein	X2CXE6	Lactobacillus_phage	1.5e-10	36.8
AWQ40519.1\|2295754_2296729_-	hypothetical protein	Q708L5	Streptococcus_phage	1.9e-70	42.7
AWQ40520.1\|2296725_2297403_-	hypothetical protein	Q708L6	Streptococcus_phage	2.6e-42	41.7
AWQ40521.1\|2297413_2302390_-\|tail	phage tail tape measure protein	Q5YA61	Bacillus_phage	9.7e-70	50.7
AWQ40522.1\|2302399_2302588_-	hypothetical protein	NA	NA	NA	NA
AWQ40523.1\|2302587_2302983_-\|portal	phage portal protein	Q20DC6	Lactobacillus_phage	1.9e-16	38.5
AWQ40524.1\|2303048_2303513_-\|portal	phage portal protein	Q708L9	Streptococcus_phage	9.4e-36	50.0
AWQ40525.1\|2303535_2304837_-\|tail	phage tail sheath protein	Q708M0	Streptococcus_phage	2.3e-111	50.9
AWQ40526.1\|2304836_2305034_-	hypothetical protein	NA	NA	NA	NA
AWQ40527.1\|2305026_2305452_-	hypothetical protein	NA	NA	NA	NA
AWQ40528.1\|2305444_2305918_-	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	2.7e-22	42.6
AWQ40529.1\|2305914_2306277_-	hypothetical protein	X5JAV9	Clostridium_phage	4.2e-07	33.0
AWQ40530.1\|2306281_2306665_-	hypothetical protein	NA	NA	NA	NA
AWQ40531.1\|2306670_2307702_-\|head	head protein	Q708M6	Streptococcus_phage	1.8e-71	45.2
AWQ40532.1\|2307704_2308286_-	hypothetical protein	Q9T1B8	Listeria_phage	1.3e-18	37.8
AWQ40533.1\|2308529_2308754_-	hypothetical protein	NA	NA	NA	NA
AWQ40534.1\|2308750_2310466_-\|head	phage head morphogenesis protein	X2CXX3	Lactobacillus_phage	6.6e-50	35.3
AWQ40535.1\|2311227_2312400_-\|transposase	IS256 family transposase IS256	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
AWQ40536.1\|2313199_2314522_-\|terminase	PBSX family phage terminase large subunit	V5UTH5	Oenococcus_phage	2.1e-157	63.7
AWQ40537.1\|2314499_2315351_-\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	7.9e-89	73.8
AWQ40538.1\|2315409_2315598_-	hypothetical protein	C9E2P9	Enterococcus_phage	1.8e-25	98.4
AWQ40539.1\|2315733_2315925_-	hypothetical protein	D2IZZ6	Enterococcus_phage	1.1e-25	100.0
AWQ40540.1\|2315962_2317297_-	chromosome partitioning protein ParB	D2IZZ5	Enterococcus_phage	8.5e-231	89.9
AWQ41412.1\|2317299_2317467_-	hypothetical protein	NA	NA	NA	NA
AWQ40541.1\|2318257_2318674_-	autolysin	C9E2P5	Enterococcus_phage	9.9e-69	99.3
AWQ40542.1\|2318736_2318826_-	hypothetical protein	C9E2P4	Enterococcus_phage	3.6e-05	100.0
AWQ40543.1\|2318818_2319019_-	hypothetical protein	D2IZZ2	Enterococcus_phage	4.6e-32	98.5
AWQ40544.1\|2319015_2319201_-	hypothetical protein	C9E2P2	Enterococcus_phage	1.1e-24	98.4
AWQ40545.1\|2319201_2319384_-	hypothetical protein	C9E2P1	Enterococcus_phage	5.9e-26	100.0
AWQ40546.1\|2319384_2319870_-	hypothetical protein	C9E2P0	Enterococcus_phage	2.4e-90	99.4
AWQ40547.1\|2319883_2320468_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	3.1e-92	85.1
AWQ40548.1\|2320479_2320683_-	hypothetical protein	NA	NA	NA	NA
AWQ40549.1\|2320694_2320889_-	hypothetical protein	NA	NA	NA	NA
AWQ40550.1\|2320892_2321099_-	hypothetical protein	NA	NA	NA	NA
AWQ40551.1\|2321105_2321297_-	hypothetical protein	A0A0E3T911	Enterococcus_phage	3.2e-06	47.1
AWQ40552.1\|2321293_2321548_-	hypothetical protein	NA	NA	NA	NA
AWQ40553.1\|2321550_2322924_-	hypothetical protein	A8ATM0	Listeria_phage	2.1e-131	53.5
AWQ40554.1\|2322920_2323340_-	hypothetical protein	Q7Y4K2	Streptococcus_phage	5.0e-20	47.9
AWQ40555.1\|2323340_2324294_-	phage replisome organizer	C9E2N2	Enterococcus_phage	1.4e-94	65.2
AWQ40556.1\|2324297_2324978_-	hypothetical protein	A0A0S2MYA3	Enterococcus_phage	1.3e-113	87.2
AWQ40557.1\|2324974_2325868_-	DUF1351 domain-containing protein	A0A0S2MYB3	Enterococcus_phage	4.2e-48	43.0
AWQ40558.1\|2325880_2326567_-	single-stranded DNA-binding protein	Q6JM07	Lactococcus_phage	3.0e-22	44.9
AWQ40559.1\|2326567_2326804_-	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	1.8e-27	82.7
AWQ40560.1\|2326787_2327207_-	hypothetical protein	NA	NA	NA	NA
AWQ40561.1\|2327227_2327419_-	hypothetical protein	A0A0S2MYB0	Enterococcus_phage	1.2e-18	94.1
AWQ40562.1\|2327555_2328284_-	hypothetical protein	NA	NA	NA	NA
AWQ40563.1\|2328267_2328483_-	hypothetical protein	NA	NA	NA	NA
AWQ40564.1\|2328624_2328951_-	DUF771 domain-containing protein	A0A1B1IMW0	Lactococcus_phage	3.9e-12	35.6
AWQ40565.1\|2328937_2329645_-	toxin-antitoxin system, toxin component, Bro family protein	Q9AZW1	Lactococcus_phage	2.4e-51	48.7
AWQ40566.1\|2329697_2329892_-	XRE family transcriptional regulator	A0A2H4JBA4	uncultured_Caudovirales_phage	3.8e-07	42.4
AWQ40567.1\|2330043_2330682_+	helix-turn-helix domain-containing protein	A0A1B2APZ3	Phage_Wrath	4.9e-59	53.3
AWQ40568.1\|2330788_2331922_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	1.9e-122	57.7
AWQ40569.1\|2332227_2332464_+	hypothetical protein	NA	NA	NA	NA
2331991:2332012	attR	NA	NA	NA	NA
AWQ40570.1\|2332404_2332623_-	hypothetical protein	NA	NA	NA	NA
AWQ40571.1\|2332537_2332810_-	hypothetical protein	NA	NA	NA	NA
AWQ40572.1\|2332915_2333545_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
AWQ40573.1\|2333676_2334915_-	serine hydroxymethyltransferase	A0A219YB23	Aeromonas_phage	1.3e-103	54.9

DBSCAN-SWA_11

2536279 : 2546019

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40759.1\|2536279_2538463_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	8.9e-286	66.6
AWQ40760.1\|2538495_2539092_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
AWQ40761.1\|2539136_2540255_-	DNA polymerase IV	NA	NA	NA	NA
AWQ40762.1\|2540380_2541139_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
AWQ40763.1\|2541122_2541785_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
AWQ40764.1\|2541799_2542672_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
AWQ40765.1\|2542783_2543131_-	initiation-control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
AWQ40766.1\|2543123_2543963_-	signal peptidase	NA	NA	NA	NA
AWQ40767.1\|2544079_2545030_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
AWQ40768.1\|2545031_2545361_-	hypothetical protein	NA	NA	NA	NA
AWQ40769.1\|2545380_2546019_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

DBSCAN-SWA_12

2566815 : 2613838

Enterococcus_phage(42.5%)

holin,tRNA,integrase,terminase,protease,tail,plate,capsid,head,portal

attL 2575567:2575584|attR 2609278:2609295

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40794.1\|2566815_2567526_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AWQ40795.1\|2567536_2568079_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
AWQ40796.1\|2568166_2568937_-	S9 family serine peptidase	NA	NA	NA	NA
AWQ40797.1\|2568926_2569133_+	hypothetical protein	NA	NA	NA	NA
AWQ40798.1\|2569102_2569678_+	DUF805 domain-containing protein	NA	NA	NA	NA
AWQ40799.1\|2569783_2571340_+	hypothetical protein	NA	NA	NA	NA
AWQ40800.1\|2571426_2572593_-	CHAP domain-containing protein	M1Q1Y5	Streptococcus_phage	8.5e-09	49.2
AWQ40801.1\|2572681_2573062_-	transcriptional regulator	C9E2L2	Enterococcus_phage	1.6e-36	59.5
AWQ40802.1\|2573751_2574816_-	FUSC family protein	NA	NA	NA	NA
AWQ41420.1\|2575071_2575269_-	hypothetical protein	NA	NA	NA	NA
2575567:2575584	attL	NA	NA	NA	NA
AWQ40803.1\|2575827_2577087_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	1.8e-230	93.3
AWQ40804.1\|2577089_2577296_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
AWQ40805.1\|2577298_2577532_-\|holin	holin	D2J075	Enterococcus_phage	7.0e-24	70.2
AWQ40806.1\|2577566_2577704_-	XkdX family protein	NA	NA	NA	NA
AWQ40807.1\|2577703_2578078_-	hypothetical protein	NA	NA	NA	NA
AWQ40808.1\|2578092_2578647_-	hypothetical protein	NA	NA	NA	NA
AWQ40809.1\|2578646_2578934_-	collagen-like protein	NA	NA	NA	NA
AWQ40810.1\|2578930_2579527_-	hypothetical protein	NA	NA	NA	NA
AWQ40811.1\|2579519_2580401_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	6.9e-11	26.1
AWQ40812.1\|2580415_2583142_-	hypothetical protein	A0A191KC22	Streptococcus_virus	2.2e-100	41.7
AWQ40813.1\|2583138_2583843_-\|tail	phage tail protein	NA	NA	NA	NA
AWQ40814.1\|2583845_2586143_-\|tail	phage tail tape measure protein	V5UPR9	Enterococcus_phage	1.8e-79	56.0
AWQ40815.1\|2586334_2586790_-	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	2.6e-14	37.4
AWQ40816.1\|2586789_2587434_-\|tail	phage tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	9.1e-29	34.1
AWQ40817.1\|2587430_2587793_-	hypothetical protein	NA	NA	NA	NA
AWQ40818.1\|2587782_2588121_-	hypothetical protein	A0A1B0T6B7	Bacillus_phage	2.1e-24	51.4
AWQ40819.1\|2588110_2588437_-\|head,tail	phage head-tail joining protein	A0A0N7IRA3	Lactobacillus_phage	6.2e-18	50.0
AWQ40820.1\|2588396_2588684_-	hypothetical protein	A0A1C8E967	Bacillus_phage	1.3e-11	42.5
AWQ40821.1\|2588686_2590018_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	1.1e-71	44.3
AWQ40822.1\|2590017_2590602_-\|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	5.0e-50	54.6
AWQ41421.1\|2590585_2591719_-\|portal	phage portal protein	A0A1B2APW5	Phage_Wrath	3.0e-83	46.1
AWQ40823.1\|2591773_2593507_-\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	6.8e-196	58.3
AWQ40824.1\|2593503_2593962_-\|terminase	terminase	A0A1B2APW6	Phage_Wrath	1.6e-24	44.0
AWQ40825.1\|2594064_2594448_-	HNH endonuclease	A0A2H4JFG4	uncultured_Caudovirales_phage	2.3e-19	44.0
AWQ40826.1\|2594440_2594728_-	hypothetical protein	NA	NA	NA	NA
AWQ40827.1\|2595253_2595721_-	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	1.7e-08	27.8
AWQ40828.1\|2596050_2596251_-	hypothetical protein	D2IYV2	Enterococcus_phage	1.8e-31	100.0
AWQ40829.1\|2596254_2596776_-	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	1.2e-44	55.1
AWQ40830.1\|2596772_2596952_-	hypothetical protein	A0A0B5A0A5	Streptococcus_phage	9.2e-16	70.7
AWQ40831.1\|2597106_2597415_-	hypothetical protein	A0A0S2MYE8	Enterococcus_phage	4.0e-59	100.0
AWQ40832.1\|2597415_2597790_-	DNA-packaging protein	D2IZL0	Enterococcus_phage	1.3e-43	72.6
AWQ40833.1\|2597833_2598598_-	site-specific DNA-methyltransferase	A0A097QQ03	Enterococcus_phage	7.2e-142	98.8
AWQ40834.1\|2598650_2598857_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	4.8e-24	95.2
AWQ40835.1\|2598872_2599478_-	hypothetical protein	NA	NA	NA	NA
AWQ40836.1\|2599497_2599968_-	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	1.9e-31	45.9
AWQ40837.1\|2600116_2600386_-	hypothetical protein	NA	NA	NA	NA
AWQ40838.1\|2600524_2601364_-	ATP-binding protein	F0PII2	Enterococcus_phage	1.7e-19	34.1
AWQ40839.1\|2601375_2602155_-	DnaD domain protein	Q6J1V6	Lactobacillus_phage	1.2e-38	60.2
AWQ41422.1\|2602169_2602973_-	hypothetical protein	J7KGZ1	Streptococcus_phage	3.9e-61	50.6
AWQ40840.1\|2602947_2603964_-	RecT protein	A0A1S5SAA8	Streptococcus_phage	1.1e-60	45.2
AWQ41423.1\|2603956_2604070_-	hypothetical protein	D2IZX5	Enterococcus_phage	3.5e-05	89.7
AWQ40841.1\|2604056_2604413_-	hypothetical protein	NA	NA	NA	NA
AWQ40842.1\|2604415_2604640_-	hypothetical protein	D2IZX4	Enterococcus_phage	3.7e-22	68.5
AWQ40843.1\|2604636_2604936_-	hypothetical protein	NA	NA	NA	NA
AWQ40844.1\|2605022_2605439_-	hypothetical protein	NA	NA	NA	NA
AWQ40845.1\|2605439_2605610_-	hypothetical protein	A0A0S2MY96	Enterococcus_phage	2.1e-17	78.6
AWQ40846.1\|2605644_2605914_-	hypothetical protein	NA	NA	NA	NA
AWQ40847.1\|2605926_2606109_-	hypothetical protein	NA	NA	NA	NA
AWQ40848.1\|2606405_2606738_+	XRE family transcriptional regulator	D2IZV9	Enterococcus_phage	5.5e-30	60.0
AWQ40849.1\|2606756_2607101_+	ImmA/IrrE family metallo-endopeptidase	D2IZV8	Enterococcus_phage	3.3e-46	78.9
AWQ40850.1\|2607158_2607887_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	6.9e-17	50.8
AWQ40851.1\|2608041_2609223_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.5e-48	31.8
AWQ40852.1\|2609325_2609475_-	50S ribosomal protein L33	NA	NA	NA	NA
2609278:2609295	attR	NA	NA	NA	NA
AWQ40853.1\|2609600_2611736_-	penicillin-binding protein 2	NA	NA	NA	NA
AWQ41424.1\|2611900_2613838_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.8e-112	36.3

DBSCAN-SWA_13

2712718 : 2721609

Staphylococcus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ40952.1\|2712718_2713891_-\|transposase	IS256 family transposase IS256	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
AWQ40953.1\|2714624_2715008_+	XRE family transcriptional regulator	E9LUL4	Lactobacillus_phage	4.7e-17	62.1
AWQ40954.1\|2715004_2715658_+	ImmA/IrrE family metallo-endopeptidase	S4U0J6	uncultured_phage	4.6e-12	34.9
AWQ40955.1\|2715696_2716032_+	transcriptional regulator	NA	NA	NA	NA
AWQ40956.1\|2716069_2717401_-	pyridine nucleotide-disulfide oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.5e-134	54.4
AWQ40957.1\|2717500_2718436_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	8.5e-44	36.2
AWQ40958.1\|2718451_2718871_-	MerR family transcriptional regulator	NA	NA	NA	NA
AWQ40959.1\|2718887_2719469_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	3.0e-31	42.1
AWQ40960.1\|2719730_2720903_+\|transposase	IS256 family transposase IS256	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
AWQ40961.1\|2721090_2721318_-	hypothetical protein	NA	NA	NA	NA
AWQ40962.1\|2721408_2721609_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.1e-23	78.8

Anti-CRISPR protein detection

Acr_ID: CP029612.1|AWQ39154.1|865832_866024_-|DUF1508-domain-containing-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP029612.1|AWQ39154.1|865832_866024_-|DUF1508-domain-containing-protein

865832_866024_-

63 aa aa

839307-881458

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP029612_1	Orphan	1.2\|1901785\|30\|CP029612\|CRISPRCasFinder,PILER-CR	1901785-1901814	30	868875-868846	0

1. spacer 1.2|1901785|30|CP029612|CRISPRCasFinder,PILER-CR matches to CP029612 position: 868875-868846, mismatch: 0

aacgtttttagggatccaaatacctttaaa	CRISPR spacer
aacgtttttagggatccaaatacctttaaa	Protospacer
******************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029612

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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