CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP013849	Clostridium botulinum strain Mauritius chromosome, complete genome	3 crisprs	DEDDh,csa3,DinG,c2c9_V-U4,WYL,cas3	0	5	7	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP013849_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP013849_1

911797-911892

Orphan

Consensus_repeat	Method
ATATACTTAAAAAGTAAATTAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP013849_1

>merge|CP013849|1|911797-911892|CRISPRCasFinder
ATATACTTAAAAAGTAAATTAATCAAATATTATCCAATATTAAATATTTATTAATATTGGATAATATTTGTTAATATAATTAAAAAGTAAATTAAT

>CP013849|1|1|911797-911892|CRISPRCasFinder
ATATACTTAAAAAGTAAATTAAT	CAAATATTATCCAATATTAAATATTTATTAATATTGGATAATATTTGTTA
ATATAATTAAAAAGTAAATTAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP013849.1\|AUM90480.1\|900321_900900_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
CP013849.1\|AUM93200.1\|923378_923840_+\|nucleoside-2-deoxyribosyltransferase	unknown	unknown	gnl\|CDD\|379753
CP013849.1\|AUM90485.1\|905770_907243_-\|toxin	unknown	unknown	gnl\|CDD\|368996
CP013849.1\|AUM90492.1\|923829_924804_+\|thymidylate-synthase	unknown	unknown	gnl\|CDD\|238211
CP013849.1\|AUM90496.1\|927916_928150_+\|ribonuclease-P	unknown	unknown	gnl\|CDD\|275333
CP013849.1\|AUM93199.1\|911218_911755_-\|transcriptional-regulator-BotR,-P-21	unknown	unknown	gnl\|CDD\|132253
CP013849.1\|AUM90481.1\|900909_901167_+\|hypothetical-protein	unknown	unknown	unknown
CP013849.1\|AUM90486.1\|907281_909534_-\|toxin	unknown	unknown	gnl\|CDD\|368996
CP013849.1\|AUM90487.1\|909547_909976_-\|toxin	unknown	unknown	unknown
CP013849.1\|AUM90489.1\|913226_916706_+\|peptidase-M27	unknown	unknown	gnl\|CDD\|366783
CP013849.1\|AUM90490.1\|916749_920640_+\|botulinum-neurotoxin-type-A	unknown	unknown	gnl\|CDD\|366783
CP013849.1\|AUM90494.1\|925619_926834_+\|thiamine-pyridinylase	unknown	unknown	gnl\|CDD\|275334
CP013849.1\|AUM90482.1\|901859_902291_+\|hypothetical-protein	unknown	unknown	unknown
CP013849.1\|AUM90495.1\|926911_927739_+\|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|180561
CP013849.1\|AUM90484.1\|903636_904773_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|372253
CP013849.1\|AUM90493.1\|924815_925574_+\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225136
CP013849.1\|AUM90483.1\|902708_903644_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
CP013849.1\|AUM90488.1\|911960_913211_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368996
CP013849.1\|AUM90491.1\|921441_922392_+\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|119376
CP013849.1\|AUM90479.1\|899863_899992_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378571

Protein	Function_ID	Function_description	E-value
CP013849.1\|AUM90480.1\|900321_900900_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.46864e-11
CP013849.1\|AUM93200.1\|923378_923840_+\|nucleoside-2-deoxyribosyltransferase	gnl\|CDD\|379753	pfam15891, Nuc_deoxyri_tr2, Nucleoside 2-deoxyribosyltransferase like.	6.05524e-05
CP013849.1\|AUM90492.1\|923829_924804_+\|thymidylate-synthase	gnl\|CDD\|238211	cd00351, TS_Pyrimidine_HMase, Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the biosynthesis of DNA precursors and are active as homodimers. However, they exhibit distinct pyrimidine base specificities and differ in the details of their catalyzed reactions. TS is biologically ubiquitous and catalyzes the conversion of dUMP and methylene-tetrahydrofolate (CH2THF) to dTMP and dihydrofolate (DHF). It also acts as a regulator of its own expression by binding and inactivating its own RNA. Due to its key role in the de novo pathway for thymidylate synthesis and, hence, DNA synthesis, it is one of the most conserved enzymes across species and phyla. TS is a well-recognized target for anticancer chemotherapy, as well as a valuable new target against infectious diseases. Interestingly, in several protozoa, a single polypeptide chain codes for both, dihydrofolate reductase (DHFR) and thymidylate synthase (TS), forming a bifunctional enzyme (DHFR-TS), possibly through gene fusion at a single evolutionary point. DHFR-TS is also active as a dimer. Virus encoded dCMP-HMase catalyzes the reversible conversion of dCMP and CH2THF to hydroxymethyl-dCMP and THF. This family also includes dUMP hydroxymethylase, which is encoded by several bacteriophages that infect Bacillus subtilis, for their own protection against the host restriction system, and contain hydroxymethyl-dUMP instead of dTMP in their DNA.	1.30025e-41
CP013849.1\|AUM90496.1\|927916_928150_+\|ribonuclease-P	gnl\|CDD\|275333	TIGR04540, CLB_0814_fam, conserved hypothetical protein. Members of this family are conserved hypothetical proteins in a narrow range of species. In Clostridium botulinum A ATCC 19397, the gene occurs immediately after a five gene operon for biosynthesis of the natural product bacimethrin, a thiamin antivitamin antibiotic.	6.93618e-25
CP013849.1\|AUM93199.1\|911218_911755_-\|transcriptional-regulator-BotR,-P-21	gnl\|CDD\|132253	TIGR03209, P-21_partial, clostridium toxin-associated regulator BotR. Clostridium botulinum neurotoxin production is regulated by a regulatory sigma-70 protein, BotR transcription regulator. Similarly, tetanus toxin production of Clostridium tetani is regulated by TetR which is a very close relative of BotR. Both BotR and TetR are members of the TIGR02937 subfamily of sigma-70 RNA polymerase sigma factors. Functional complementation experiments have been done for botR and tetR in highly transformable strain of Clostridium perfringens host cells to assess functional interchangeability of sigma factors and it has been confirmed that they are interchangeable in vivo.	3.01805e-62
CP013849.1\|AUM90495.1\|926911_927739_+\|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase	gnl\|CDD\|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	5.65524e-134
CP013849.1\|AUM90486.1\|907281_909534_-\|toxin	gnl\|CDD\|368996	pfam06597, Clostridium_P47, Clostridium P-47 protein. This family consists of several P-47 proteins from various Clostridium species as well as two related sequences from Pseudomonas putida. The function of this family is unknown.	1.93266e-33
CP013849.1\|AUM90485.1\|905770_907243_-\|toxin	gnl\|CDD\|368996	pfam06597, Clostridium_P47, Clostridium P-47 protein. This family consists of several P-47 proteins from various Clostridium species as well as two related sequences from Pseudomonas putida. The function of this family is unknown.	2.66182e-65
CP013849.1\|AUM90489.1\|913226_916706_+\|peptidase-M27	gnl\|CDD\|366783	pfam01742, Peptidase_M27, Clostridial neurotoxin zinc protease. These toxins are zinc proteases that block neurotransmitter release by proteolytic cleavage of synaptic proteins such as synaptobrevins, syntaxin and SNAP-25.	7.81679e-81
CP013849.1\|AUM90490.1\|916749_920640_+\|botulinum-neurotoxin-type-A	gnl\|CDD\|366783	pfam01742, Peptidase_M27, Clostridial neurotoxin zinc protease. These toxins are zinc proteases that block neurotransmitter release by proteolytic cleavage of synaptic proteins such as synaptobrevins, syntaxin and SNAP-25.	0
CP013849.1\|AUM90494.1\|925619_926834_+\|thiamine-pyridinylase	gnl\|CDD\|275334	TIGR04541, Thiaminase_I_Thiamine_pyridinylase., thiamine pyridinylase. Members of this family are thiamine pyridinylase (EC 2.5.1.2), also called thiaminase I. Most examples of this secreted, thiamine-degrading enzyme are encoded with a cluster for biosynthesis of the thiamine antivitamin bacimethrin. [Cellular processes, Biosynthesis of natural products].	0
CP013849.1\|AUM90493.1\|924815_925574_+\|SAM-dependent-methyltransferase	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	2.84917e-21
CP013849.1\|AUM90484.1\|903636_904773_+\|ABC-transporter-permease	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	1.39629e-11
CP013849.1\|AUM90491.1\|921441_922392_+\|glycosyl-hydrolase	gnl\|CDD\|119376	cd06414, GH25_LytC-like, The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.	8.053e-88
CP013849.1\|AUM90488.1\|911960_913211_+\|hypothetical-protein	gnl\|CDD\|368996	pfam06597, Clostridium_P47, Clostridium P-47 protein. This family consists of several P-47 proteins from various Clostridium species as well as two related sequences from Pseudomonas putida. The function of this family is unknown.	9.59002e-19
CP013849.1\|AUM90483.1\|902708_903644_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.61505e-87
CP013849.1\|AUM90479.1\|899863_899992_+\|hypothetical-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	0.000196527

>CP013849.1|AUM93199.1|911218_911755_-|transcriptional-regulator-BotR,-P-21
MENLFFIIKILKDNNKKFEDIYMNYKNLIDIFIKKYNLSENYNDILNHFWIILIKADLNKFNTENDLNKYISKCLKRYCLSICMKKNRDKKIIYNSEITDINLNLIQDNCFNDIEFEFKDLISILPNTQQNIIYMKFFKDMKDIEIAKKLKISRQSVYKNKSLALEKLKPILKELINI
>CP013849.1|AUM90487.1|909547_909976_-|toxin
MKQTFSFNFDDTLSNSSGLIHLEKVNQNCSPNYQYFKIKFIEGYLHIKNKSGNILEKYDLKDLISLIALKKDYLKLSPLNNKKPKEFTNMKNKHLENRFNLYIINGDIYKKITKNGFLEEIILNRLLLSILLGNEENLLQIA
>CP013849.1|AUM90486.1|907281_909534_-|toxin
MNNLKPFIYYDWGKTILKNTKENYSTNEIIPKTFSMELNGTKITNSTLNGTWKSWNLTDEGEGSHPVLKCIIDDGYLDMNFGASSEKIPLKNVWIKLCMKINPNSDGTYSIPEKSSSFYIKDNSLKISKDNLILDKYLNKLMLSYFKNNIKNIEMFINKSRIQTKVVGDLSLLGWNTENSVSFRTMNEFIKKDNLYPKDFKAVYSYRKMTFTATGTFDSWEMTTGADGRNIRFKCPIKSAAYDLDGDVFNSSTENFLLIQVDLTYFDSKTTINDPTGENDGKQFNLKVKTNDDKLKNVLIVTYNLTDTDGSMSSEDKDFLSLAFRNWFNENIQQFEQIFAYILLDETAKIPEYQWLKPTQISYGSASVETANDEPDLDASIFSAMSMVENNTNSTPSHAVDNRMLQLTKTQAAFGISFPLFIEHFLKQALLSSQFISVDDIVADINTLTITNNKQIIFGKVENSDGKNVDSSLKPGKLKLSLQNNLIVLELFDLTWEQGRGVTGHFDFRQEYELALEAKSGNQIPILKVHDEPEIEYYVEEAQWKTNEDMIVSAVVGTVFSMILGASMKLAGSALSKAGKLIRSKATTIKGRKKIYINRSNVRQLRKDSGVTEIELQRINRRNSSIAAEDARLISNNGTTSIQTLGDMKKKPMSTGQRIAIGAKKIAGTAVMFGAVGLGMNFGEMLINYINAMENNDYSAIPGINSFMQQCIGAMQWPDKDSELKVTFGKLQGIYLLGGTLEKNNKPNSK
>CP013849.1|AUM90485.1|905770_907243_-|toxin
MQTTTLNWDTVYAVPIDIVNEAIKFKHPTPEQFELLDGKYGDCKGSFQEWQIISGGDGGNIRLKIPIKNFKANVIGKYLSGTGGFESANLEIQVKLKYLPHFPQSKNKNEELVDLKIRTKSNNAEDPAIIIIPTSEDVKGFYFNEDVRSLLMTEDDQFIMNYFHRLIKEWLERNLYFFNYVFNTVNLNLYISNNEKWKWTKPSYVDYAYSEIDGDLSKSALGVLCMTDGRKGSKIQQQKIDPNAIPKTSQSGFLISEERLLKNILLPTIPKKFPKCKGDEFEVINQSSQGGGYSYILKLKEGKKIDLDNINASGYTCTPYIQKMKVSLLGNYLRLESTTRVDLPVGVSSICETMCEYRFKLGKNDRGEQTIAYEQIGSPINKQYTEKTQDVGFEIIKGLLIATLGFVLELVPGVGSFLAVALIGGILVGSISLIPSFIEDYNVNAAPSIDLSLENSVSEITWNSSDIFNLNYVALAGPLQLGGTLQVQNT
>CP013849.1|AUM90484.1|903636_904773_+|ABC-transporter-permease
MTKYIWQELKRVLIKKKISLIIILILTIVFGGINILKQKTLEEKLEQTKIILDDQIGSKKDEKIINDTREQISYIEETLSMIKNYDKSKIDEKILKLEKENNPKNYYEIKKLKYEKEHNIEKNELVPKGMYATINILGVSDISILYIIILIVLLSDIVSGEYSPNTIKMSLTKPISRKKIIISKFAVSIITGASVIIISTIIFVVEAGIRFGLSDYRMPVYLGTKYVLNKSLPLTVETSQMERAANSISVVPLWSMIVRFVLIAILVSIVSISILMFISTLCKKSLISSIINFILVIVTSLMFIWGIMDNNILATKYGVLLKFTSIPYIIDIFEVLSGYISVGLASSINIFFVLIVCLGWSLIMMFLSTYIFAKRDFD
>CP013849.1|AUM90483.1|902708_903644_+|ABC-transporter-ATP-binding-protein
MEENEPVLDVKNISKKRGKTPILKDVNFSIGKGEICGFVGRNGAGKTTLMKIITSMLFPDEGEIIICGKNLKTEREEALKNIGAVVETPEMYGYLTGRQNLNYIASMLEDVTKDDIEEAIRYSNLGDKIDEKVKKYSLGMKQRLGLAQALIGDVSLLILDEPTNGLDPLGVVELKNTINTLVKEKGVSVFISSHILSEIESICTKVVFIDNGKIINIEKMDEEPQVNNIKNMFINTDLPEKAAEIIKSIPDIELLKVEKNGVSVLVNTDICDITKILITLHNEGVKVEGFSEVKEKLEDKFIKIVGDNNND
>CP013849.1|AUM90482.1|901859_902291_+|hypothetical-protein
MINNIMKNNKLVDMLEEESYIENDERIHKIYSEIDKEKYTIIFLALLTFYLYELMILQKNDTPLVFFIILDGIYTDIRLAMNKAYIKTNLKYMETCCWLLLLLRYFKYKFLININFMIIIIISFVIGYLYIKLMLYISNKSKI
>CP013849.1|AUM90481.1|900909_901167_+|hypothetical-protein
MKNLDVKQHTKKCMDFAKKAGVGSFPNKEVAKVGSMVGVGIGAVLLGIGIYGISQSSVYGTGSLAVGAVAGISNCANLKRIKRKK
>CP013849.1|AUM90480.1|900321_900900_+|TetR-family-transcriptional-regulator
MPKGFTENEKTIITEKLIKECKSNWQKYGYKKTSIDVLCRDIGISKGSFYSFFDTKEDLFYQVIKETQEHLYEIVEERISQNQSKYGVAEALKEIYLEYSKSSFMYDTKNPDFLSFFNKLSEQQRKELTEKSYVGTKFMLNKPFLSLKIDEDLAISVLTAMLTSISQKDKMLCDSVKVFGFMIDNLIDDIFN
>CP013849.1|AUM90479.1|899863_899992_+|hypothetical-protein
MIKNCGKAIVNKNIFQNTNGDLSSFKVARIITTETEEIIIEE
>CP013849.1|AUM90488.1|911960_913211_+|hypothetical-protein
MNTYGWDIVYGCSKRVVNKHLEDYITKNKVEFLYSNTAKKQEIKMAFDNWEIINGGSSNFLRIKTPIKEGYFKVKNTTIDLSGVNPVLEIKLDFFNDLSNPNIKKLKFNFGSESNDDIKIIVSDLNGKLQEEDEFYFNKLLINAFIQNEKQISYIFASLNVTSDIEWMNPKQFKFVYYSPTDNSAGYLFILSVVTNRDISKLSTNVDGNILGNNSEVGLLISEKLFLQNLALPKLSSNMGSNITSNNFKVISTSDTTGRIANNSTLNWYGLKVGLIWYYPKINNFSMELFEGNKLKTKLSGIVRLTGYERIYSELNLECTTKFIYDPKNKKASFEDYKTSIMSCKPIFGWLDGAAALVAKSVGDWSLKSFRGSLAFGLTNNFTDIINGIVRWNNLKISQVTNVTLNVGFCIQGNAN
>CP013849.1|AUM90489.1|913226_916706_+|peptidase-M27
MKINNNFNIDSPVDNKDVAIVRGRKIDAFFKAFQVAPNIWVAPERYYGESLNINEDQKSDGGIYDSNFLLTNDEKDEFLQATVKILQRINNNVVGAKLLSLISTAIPFPYEYKPGDYRQTNYLVSKDNQHYYTANLVIFGPGTNIVENNAVYYKKEDSENGMGTISEIWFQPFLTYKYDQFYVDPALELIKCLIKSLYYLYGIKPSDDLSIPCRLRSEFNSLEYSELDMVDFLISGGIEYKLLDTNPYWFTDNYFIDAPKNFEKYKNDYETKIKNNNDIANSIKLYLEQKFKINAQDIWELNLSYFSTEFEIMMPEIFNNALNHYYRKEYYVIDYFKNYNINGFINGQIKTILPLSKYNKNIINKPELVVNLINEDNAVLMKSNVYGDGLKGTMDNFYAAYKIPYNIGDEYHINYSYLNNVNVEEINNIPPINDADIYPYRKNSDPFIPVYNITETKEINTTTPFSVNYLQAQVANSNDISLSSDFSKVISSKDRSLVYSFLDNTIDYLDSIKYDEPINTDKKYYLWLKDIFRNYSFDMTETQEVNTLYGINKVVPWLGKALNILNTGNSFIEEFKSLGPISLINKKENITMPKIEIDEIPNSMLNLSFKDLSENLFNRFSKNNSYFEKIYYDFLDQWWTQYYSQYFDLICMAKKSILAQESLIKKIIQKKLSYLIGNSNISSDNLALMNLTTTNTLRDISNESQIAMNNVDSFLNSAAICVFEGNIYSKFISFMEQCINNINKNTREFIQKCTNITENEKLQLINQNIFSSLDFDFLNIENLKSLFSSETALLIKEETSPYELVLYAFQEPDNNAIGDASAKNTSIEYSKDIDLVYGINSDALYLNGSNQSISFSNDFFENGLTNSFSIYFWLRNLGKDTIKSKLIGSKEDNCGWEIYFQDTGLVFNMIDSNGNEKNIYLSDVSNNSWHYITISVDRLKEQLLIFIDDNLVANESIKEILNIYSSNIISLLSENNPSYIEGLTILNKPTTSQEVLNNYFKVLNNSYIRDSNEERLEYNKTYQLYNYVFSDKPICEVKQNNNIYLTINNTNNLNLQLSKFKLLSINSNKQYVQKFDEVIISILGNMEKYIDISEDNRLQLIDNKNGAKKMIISNDMFISNCLTLSCGGKYICLSMKDENHNWMIRNNDMSKYLYLWSFK
>CP013849.1|AUM90490.1|916749_920640_+|botulinum-neurotoxin-type-A
MPFVNKQFNYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHDVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAEHRLYGIAINPNRVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDVASTLNKAKSIIGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVNFFKVINRKTYLNFDKAVFRINIVPDENYTIKDGFNLKGANLSTNFNGQNTEINSRNFTRLKNFTGLFEFYKLLCVRGIIPFKTKSLDEGYNKALNDLCIKVNNWDLFFSPSEDNFTNDLDKVEEITADTNIEAAEENISLDLIQQYYLTFDFDNEPENISIENLSSDIIGQLEPMPNIERFPNGKKYELDKYTMFHYLRAQEFEHGDSRIILTNSAEEALLKPNVAYTFFSSKYVKKINKAVEAFMFLNWAEELVYDFTDETNEVTTMDKIADITIIVPYIGPALNIGNMLSKGEFVEAIIFTGVVAMLEFIPEYALPVFGTFAIVSYIANKVLTVQTINNALSKRNEKWDEVYKYTVTNWLAKVNTQIDLIREKMKKALENQAEATKAIINYQYNQYTEEEKNNINFNIDDLSSKLNESINSAMININKFLDQCSVSYLMNSMIPYAVKRLKDFDASVRDVLLKYIYDNRGTLVLQVDRLKDEVNNTLSADIPFQLSKYVDNKKLLSTFTEYIKNIVNTSILSIVYKKDDLIDLSRYGAKINIGDRVYYDSIDKNQIKLINLESSTIEVILKNAIVYNSMYENFSTSFWIKIPKYFSKINLNNEYTIINCIENNSGWKVSLNYGEIIWTLQDNKQNIQRVVFKYSQMVNISDYINRWIFVTITNNRLTKSKIYINGRLIDQKPISNLGNIHASNKIMFKLDGCRDPRRYIMIKYFNLFDKELNEKEIKDLYDSQSNSGILKDFWGNYLQYDKPYYMLNLFDPNKYVDVNNIGIRGYMYLKGPRGSVVTTNIYLNSTLYEGTKFIIKKYASGNEDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKDDQGIRNKCKMNLQDNNGNDIGFIGFHLYDNIAKLVASNWYNRQVGKASRTFGCSWEFIPVDDGWGESSL
>CP013849.1|AUM90491.1|921441_922392_+|glycosyl-hydrolase
MLKGIDASEHQGEICWKAVKNSGIQFAILRAGYGKNNIDEQFINNANGCTSVGMPFGLYWFSYAYTEDMARKEAQYCVAQAKKYKISYPICYDLEYDTIRYANNCGVTITKSLATKMVHAFCQEVERNGYFAMNYSNQDFLLNKFDSDLLKRYELWYAWYNNSLNRKCGIWQYSENGRVPGIAGVAVDMNYCYLNMSGAYNTSPNKNTFRGGHYLIRELQQEINSQGLREVVVDGIAGQATINSVPVCKQGARGGITKVIQQILISIGYPVGSHGADGVFGDSTVTAIKAFQRDCHLVADGIVGKETWKALFRNLK
>CP013849.1|AUM93200.1|923378_923840_+|nucleoside-2-deoxyribosyltransferase
MSKRVFLAAPFKGAIKEKQSIMKEQEKKRIENLILFLEEKGWKVDNAHKREEWGANSMSPDQCTKLDYDAIKECDLFIAFPGVPVSPGTHIEIGWASAMGKKIILLLAEKEENYAYLIRGLHTVSNVHYIIYNEEKEYLQKLNLYLDGENNEV
>CP013849.1|AUM90492.1|923829_924804_+|thymidylate-synthase
MKFKNFHEAYLKNLNDVYYNPEFINQPRGNVSKERLNYFMILENPRERICYTKSRKTNIVFNFAEALWYLSGSNDLDYISYYASNMKKYSMDGKTLTGTAYGPKIFSYGYNKINQWNRIIKLFKEDPDTKRGFIEIFDANEDLSLKNIDVSCTIGFQFFIREHKLYMTTFMRANDAYRGIISDVFSFTFIQEFLATELNLDIGQYSHQVATTHIYEPDFKLAEKVLCESKSVKKELSFPRMPKKDNWEDLKIVLQYEKELRKQRIHLTKKDIDELEIDKYWKQIICLFVLYQEIYYGDNLDYEIYESLEPLYQYLFSNKWNQYF
>CP013849.1|AUM90493.1|924815_925574_+|SAM-dependent-methyltransferase
MGTCWKDEEVSKKFNLYNDMLENILGFDYIFQNLKSNESIKKILDFGCGPGKVAERMAKIKPESQIIAVDQSQNMLDIAMKEHNKENIDYRLIEQNQLKGIEKNSIDCVVLCFVIINNSDKDRIKTIFQEIFRVLKKGGKFFILDSNPNAAGVEFSTFTNGKSGQAYRLGDHKKQFLKIPNNKVLILEDYYWPIDFYINNLEAVGFENYKIVEPTIEKINKRDLNAIEKTYDIKCWGSEKNKPPFIIFDVEK
>CP013849.1|AUM90494.1|925619_926834_+|thiamine-pyridinylase
MKFKNLFKRSLSLLFSFIMIFTLVSGLNVKAFSGDEPKQTLNVALYEYVPDPIRFKKAVETEWNKKEPNIKLNFVDWDCYSEDPPKDLDVFVFDAIYLSHFVKKGYLSEIPEKDIKNKEDILPFAMEGCTIKGSAYAIPQIICTNLLFSRKGDYDIQKVNSVYDLYDKLGKFTSEDIILPNNKGLLIDMSGGTSKACMYLDSLIDTTQEYTKFCSLPNLNELNKDAIESLVLLQSMAGKSQANYWPENNDSYIRAKWFINGKGRAYIGYTEAMSQMKEFANDIDFKTISLSKNSNIPIFYGDVVGINSSITNPYKKEKAIELANIITDKSTMVKAVSPDENNEYPQYLLPARRSVYHNLENKYPIYGRLYKIAHNPNNKLFRTGPEIREWLKQAKKIITEYLQQ
>CP013849.1|AUM90495.1|926911_927739_+|hydroxymethylpyrimidine/phosphomethylpyrimidine-kinase
MKKVLSIAGSDCSGGAGIQADLKTFSAHGVFGMSVIVSVVAENTSRVIDIQDITPDMIKSQIDAVYEDIGTDAVKIGMLSTPDCMKAVSEKLQEYKPKNVVIDPVMYAKNGCPLMDPNSVSTLIESIICHADILTPNIPEAERISGYKIKTLEDMEKAAVIIEGMGCKSVLIKGGHYIGDAVDVLYDGNKFYHYKTQRIHTKNTHGTGCTLSSAIASNLALGFEINEAVKRAKNYITMAIEHSLEIGKGNGPTNHFYQVYLNGLKGMELDNHTRS
>CP013849.1|AUM90496.1|927916_928150_+|ribonuclease-P
MRKVYKNPKELATCLKDLVDLYFEDLMTYEKLEEKVSKIVEANKDSIYKNGVINTKLANVLGNLRIDVINKIVKEEN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP013849_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP013849_3

2362371-2362466

Orphan

III-B

Consensus_repeat	Method
ATTTAAATACATCCTATGTTAAGGTTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP013849_3

>merge|CP013849|3|2362371-2362466|CRISPRCasFinder
GCTTAAATACATCTTATGTTACTGTTCAACTACAAATCCAAAAGAAATTGATTTAAATCAAATAAAATTTAAATACATCTTATGTTACTGTTCAAC

>CP013849|3|3|2362371-2362466|CRISPRCasFinder
GCTTAAATACATCTTATGTTACTGTTCAAC	TACAAATCCAAAAGAAATTGATTTAAATCAAATAAA
ATTTAAATACATCTTATGTTACTGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP013849.1\|AUM91773.1\|2371264_2372113_-\|phenazine-biosynthesis-protein-PhzF-family	unknown	unknown	gnl\|CDD\|223461
CP013849.1\|AUM91754.1\|2348869_2350009_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|341476
CP013849.1\|AUM91755.1\|2350572_2352564_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
CP013849.1\|AUM91761.1\|2358782_2359220_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|182417
CP013849.1\|AUM91762.1\|2359243_2359960_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
CP013849.1\|AUM91765.1\|2362628_2362898_+\|peptidase-M24	unknown	unknown	gnl\|CDD\|238518
CP013849.1\|AUM91766.1\|2362981_2363155_+\|metallopeptidase,-family-M24	unknown	unknown	gnl\|CDD\|238518
CP013849.1\|AUM91768.1\|2364737_2365478_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|100107
CP013849.1\|AUM91772.1\|2370076_2370946_-\|phenazine-biosynthesis-protein-PhzF	unknown	unknown	gnl\|CDD\|223461
CP013849.1\|AUM91759.1\|2357092_2358457_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP013849.1\|AUM91774.1\|2372481_2372715_-\|hypothetical-protein	unknown	unknown	unknown
CP013849.1\|AUM91757.1\|2354108_2354462_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
CP013849.1\|AUM91771.1\|2368560_2369358_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP013849.1\|AUM91763.1\|2360863_2361598_-\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
CP013849.1\|AUM91760.1\|2358469_2358754_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|99905
CP013849.1\|AUM91756.1\|2352553_2353321_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP013849.1\|AUM91769.1\|2365822_2366344_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
CP013849.1\|AUM91758.1\|2354787_2356881_-\|sugar-transporter	unknown	unknown	gnl\|CDD\|226234
CP013849.1\|AUM91767.1\|2363228_2364635_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340904
CP013849.1\|AUM91770.1\|2366455_2368453_-\|2-enoate-reductase	unknown	unknown	gnl\|CDD\|239241

Protein	Function_ID	Function_description	E-value
CP013849.1\|AUM91773.1\|2371264_2372113_-\|phenazine-biosynthesis-protein-PhzF-family	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.39603e-61
CP013849.1\|AUM91754.1\|2348869_2350009_-\|3-dehydroquinate-synthase	gnl\|CDD\|341476	cd08197, DOIS, 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose. 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics. 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotics includes neomycin, kanamycin, gentamicin, and ribostamycin. They are important antibacterial agents. DOIS is a homolog of the dehydroquinate synthase which catalyzes the cyclization of 3-deoxy-D-arabino-heputulosonate-7-phosphate to dehydroquinate (DHQ) in the shikimate pathway.	1.73999e-153
CP013849.1\|AUM91755.1\|2350572_2352564_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.000529996
CP013849.1\|AUM91761.1\|2358782_2359220_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|182417	PRK10372, PRK10372, PTS ascorbate transporter subunit IIA.	4.73815e-38
CP013849.1\|AUM91762.1\|2359243_2359960_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	6.47741e-157
CP013849.1\|AUM91765.1\|2362628_2362898_+\|peptidase-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	5.99944e-08
CP013849.1\|AUM91766.1\|2362981_2363155_+\|metallopeptidase,-family-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	7.33995e-13
CP013849.1\|AUM91768.1\|2364737_2365478_-\|SAM-dependent-methyltransferase	gnl\|CDD\|100107	cd02440, AdoMet_MTases, S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).	1.79931e-11
CP013849.1\|AUM91772.1\|2370076_2370946_-\|phenazine-biosynthesis-protein-PhzF	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.17736e-88
CP013849.1\|AUM91759.1\|2357092_2358457_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP013849.1\|AUM91757.1\|2354108_2354462_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
CP013849.1\|AUM91771.1\|2368560_2369358_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.47479e-15
CP013849.1\|AUM91763.1\|2360863_2361598_-\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.39268e-11
CP013849.1\|AUM91760.1\|2358469_2358754_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	1.57443e-28
CP013849.1\|AUM91756.1\|2352553_2353321_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.33605e-104
CP013849.1\|AUM91769.1\|2365822_2366344_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	1.23442e-25
CP013849.1\|AUM91758.1\|2354787_2356881_-\|sugar-transporter	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.34931e-56
CP013849.1\|AUM91767.1\|2363228_2364635_+\|MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.9059e-120
CP013849.1\|AUM91770.1\|2366455_2368453_-\|2-enoate-reductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0

>CP013849.1|AUM91763.1|2360863_2361598_-|transpeptidase-transglycosylase
MDKFRNMKKSHIALLVVMYMVLMGSLPRFTGWATIFSAIAVGGYFLKNKKDLKELTKKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKMMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEESKKKAEEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNESENVDNNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARSEGLSPCSVCNP
>CP013849.1|AUM91762.1|2359243_2359960_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVEALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>CP013849.1|AUM91761.1|2358782_2359220_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINNQVVEVNAEVKNWEEAVRLGGKLLEKDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>CP013849.1|AUM91760.1|2358469_2358754_-|PTS-maltose-transporter-subunit-IIBC
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEQLKK
>CP013849.1|AUM91759.1|2357092_2358457_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>CP013849.1|AUM91758.1|2354787_2356881_-|sugar-transporter
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGINLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMEREELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDISDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKRDFIKLNEEAKDWEDAVRKSGEILMNNGCIKKSYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKINHMKALKELMSIMDQEDFISKVKNIKASSEIDSILYS
>CP013849.1|AUM91757.1|2354108_2354462_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>CP013849.1|AUM91756.1|2352553_2353321_-|multidrug-ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIIINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDEKVKSVAKYLEIEKVLNKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELVRGNDTRKEFFNKIIEVTSLLGGDDNNVF
>CP013849.1|AUM91755.1|2350572_2352564_-|ABC-transporter-permease
MYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIRSSGGSYVSRLMDFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVTETSIVGVISLIAGLIIGMGVSQGLSVFALKLFEVGINEYRFAVSTRAISKTILYFGIMFLLVMIFNIFVISKYKIIDLLTSGRKNENIKFKNKFIYSLSFLLCVVLLGFAYKSILKTGLKLREPMFKPSIAFVIVGTVLFFFTLAGVILYVVNKNKKIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILILSTGISFKNGLEEGVKIRAPFDASIIISNNSKKNNLEDVLDKINFKRSKDEKYVTCNEYLSGIKLESLLSITDKDYKDREVSFVKISDYNKILKLKGKKEINLNKDEILVMSTNNAVVKQANEKLKNSKKFNIKGKEYLVKNNKIIEENLATYLLADNVFTIVISDEFLYDYNKIVYSILNVMYSDKNREENNKKYSEINKNFVGGKYKNLNISYMGAFSKDDIYSHSKGGTTSILFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKVLKRIGANSKMIEKTIFLQTLIYFALPMILALVHSMIGIKVISDYIEVFTKIDISFSALITALIFSVVYAGYFYTTYTGYKNIVKSNI
>CP013849.1|AUM91754.1|2348869_2350009_-|3-dehydroquinate-synthase
MYMNLAQKINDDYYHPEVKLETNLLESSPIYLGCNIWRESLLEKMMDLNTDKFFLITDDVVYNLFGKELLEYMNRKASVKLIKLPSGEKHKNIKVFNDLMEDLFDNNVTKSSILISLGGGVVGNITGLAAALAFRGIRFFHIPTTFMSQTDSILSRKQGINSFYGKNMIGSYYTPLFNFIDTSFLTFDSERFIRGSFVETVKNGFIYNADFLNKLKSVIKNDFNVNQEGIFNLVKMSIESKLPIMKADPTEKGLAMILEYGHTVGHAIEKLSYGKLSHGESVSIGMMVAARISEKLGYLSKQDVKEHMDILSALKTPTKIPSNIKISDIINRIKLDNKKDINGIRFVVLQNIGKCINTDGSYMIKVPFNIINDAIEETC
>CP013849.1|AUM91765.1|2362628_2362898_+|peptidase-M24
MHLFINEIKLNDEIKSNLKENGALFIHPYNKIYKEVITEIGSSNKLDAFPAEQGRFIRPSFEPISSFGEHATIVTCILLMDNSFMIVTV
>CP013849.1|AUM91766.1|2362981_2363155_+|metallopeptidase,-family-M24
MNIHEAPAGFRWQYRPKETHRFEEGIVITDEPGIYIAGSHGIRIENELIVCKGENNG
>CP013849.1|AUM91767.1|2363228_2364635_+|MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFSKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSIESVSTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>CP013849.1|AUM91768.1|2364737_2365478_-|SAM-dependent-methyltransferase
MVNYYGSLCTTMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFESSIEEFSPKEKYDYIFITSGSFSLFLDEDSAFNVLVKIKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFRIKLYDFGELDKLILKAGFKRRHVFSDFNRRKSIDKNTETFLYECYI
>CP013849.1|AUM91769.1|2365822_2366344_+|DUF4825-domain-containing-protein
MKNKFKILVPLLLILSLNLIGCGVNSERKSKENVKNSSKVETYDLIKYKGAYIGDNSSVGSIIKNLPANEYSAGFSLQTSKEPYEITINYKANENLGEENYNKFWSDKKANKLLEKNAVVLLSLIPNAEIIKFNVDSIGEESYKYDKKNLEQKYGNLKDLFKDNDSLNKFLNN
>CP013849.1|AUM91770.1|2366455_2368453_-|2-enoate-reductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENSIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPGEEFEEKGRDIPEGIEAAKMLVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKNAVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAVRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLDVEIKLNVDVSKENIKEFGADEVLLATGSSPRTLTIEGADNVYSAEDVLMERKNVGEKVIVIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNKVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>CP013849.1|AUM91771.1|2368560_2369358_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIKVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKELKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>CP013849.1|AUM91772.1|2370076_2370946_-|phenazine-biosynthesis-protein-PhzF
MKVKAYTLNSFAKCIEGGNPAGVVINADDLSEDNMKKVAGIIGFSETAFVMNSDLADFKVRFFTPNEEVDICGHATIATFSTLLSQGRIEPGKYFQETKAGVLSVELKEDLSIMMNQNTPSYYETICKQEIADSLNITTAEMSEELPIQIVSTGLRDILIPIKNIDMVNAIKPNFEKVSRISSKYNTIGYHIFTLESLNGSNAYCRNLAPLYGIPEESATGTSNGALACYLFKYGKIKSDNTNHIVIEQGYSMEKPSEIIVSLITEGKEVIEIKVGGKALNLSEIEVEI
>CP013849.1|AUM91773.1|2371264_2372113_-|phenazine-biosynthesis-protein-PhzF-family
MEYFHVDVFSNEILYGNGLTVVFCNEELEDNLMLKLTQEFKQFETIFVRRIDNSIFNARIFTVDEELDFAGHPILGAAATIHSNIFRNEEDIAITFQLNQKTIIVNSKKIEEYYEVQMNQGKAEFLCEVSKEKRNKYVHALNLSEENLSEEFPMEVVSTGLPYLLVPLTSGIENAKIISSKFEEMLKEVGAKFAYIFDVNYIEGRTWDNQGNVEDVATGSAAGPLGAYLYKHNIFNVGHEIIINQGRFVGRPSKIKVSMSISEKEILVSGEVAILAKGTILL
>CP013849.1|AUM91774.1|2372481_2372715_-|hypothetical-protein
MNQGQEKFLGFILERVEEDKVEEAKALLADNFKKQVEGNFTHDDITEFIPKMAMLLKPDKIEEVQTVMKQFAENFSH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: CP013849_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP013849_2

2361891-2362119

Orphan

III-B

Consensus_repeat	Method
TATTTAAATACATCCTATGTTAAGGTTCAAC	CRT
ATTTAAATACATCCTATGTTAAGGTTCAAC	CRISPRCasFinder
ACATATTTAAATACATCCTATGTTAAGGTTCAACC	PILER-CR

3 spacers

The CRISPR arrays of CP013849_2

>merge|CP013849|2|2361891-2362119|CRT,CRISPRCasFinder,PILER-CR
TGCTTAAATGCATCCTATGTTAATGTTCAACACTAACATTTGGTCATTTTTCCCTATACATTCACAAATTTAAATACATCCTATGTTAAGGTTCAACCTGAAAAGCCTGGTACTAAAAACGTAGTTGACGTATTTAAATACATCCTATGTTAAGGTTCAACTAGTAGGGTCTTCTTTTACTTCACTTAATTCTAAGATATTTAAATACATCCTATGTTAAGGTTCAACC

>CP013849|2|1|2361891-2362118|CRT
TGCTTAAATGCATCCTATGTTAATGTTCAAC	ACTAACATTTGGTCATTTTTCCCTATACATTCACA
AATTTAAATACATCCTATGTTAAGGTTCAAC	CTGAAAAGCCTGGTACTAAAAACGTAGTTGACG
TATTTAAATACATCCTATGTTAAGGTTCAAC	TAGTAGGGTCTTCTTTTACTTCACTTAATTCTAAGA
TATTTAAATACATCCTATGTTAAGGTTCAAC

>CP013849|2|2|2361892-2362119|CRISPRCasFinder
GCTTAAATGCATCCTATGTTAATGTTCAAC	ACTAACATTTGGTCATTTTTCCCTATACATTCACAA
ATTTAAATACATCCTATGTTAAGGTTCAAC	CTGAAAAGCCTGGTACTAAAAACGTAGTTGACGT
ATTTAAATACATCCTATGTTAAGGTTCAAC	TAGTAGGGTCTTCTTTTACTTCACTTAATTCTAAGAT
ATTTAAATACATCCTATGTTAAGGTTCAACC

>CP013849|2|1|2361954-2362119|PILER-CR
ACAAATTTAAATACATCCTATGTTAAGGTTCAACC	TGAAAAGCCTGGTACTAAAAACGTAGTTG
ACGTATTTAAATACATCCTATGTTAAGGTTCAACT	AGTAGGGTCTTCTTTTACTTCACTTAATTCTA
AGATATTTAAATACATCCTATGTTAAGGTTCAACC

Protein	Signature genes	Signature genes Name	Protein_function
CP013849.1\|AUM91773.1\|2371264_2372113_-\|phenazine-biosynthesis-protein-PhzF-family	unknown	unknown	gnl\|CDD\|223461
CP013849.1\|AUM91754.1\|2348869_2350009_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|341476
CP013849.1\|AUM91755.1\|2350572_2352564_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
CP013849.1\|AUM91761.1\|2358782_2359220_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|182417
CP013849.1\|AUM91762.1\|2359243_2359960_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
CP013849.1\|AUM91764.1\|2362454_2362634_-\|hypothetical-protein	unknown	unknown	unknown
CP013849.1\|AUM91766.1\|2362981_2363155_+\|metallopeptidase,-family-M24	unknown	unknown	gnl\|CDD\|238518
CP013849.1\|AUM91768.1\|2364737_2365478_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|100107
CP013849.1\|AUM91772.1\|2370076_2370946_-\|phenazine-biosynthesis-protein-PhzF	unknown	unknown	gnl\|CDD\|223461
CP013849.1\|AUM91759.1\|2357092_2358457_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
CP013849.1\|AUM91757.1\|2354108_2354462_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
CP013849.1\|AUM91771.1\|2368560_2369358_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
CP013849.1\|AUM91765.1\|2362628_2362898_+\|peptidase-M24	unknown	unknown	gnl\|CDD\|238518
CP013849.1\|AUM91763.1\|2360863_2361598_-\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
CP013849.1\|AUM91760.1\|2358469_2358754_-\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|99905
CP013849.1\|AUM91756.1\|2352553_2353321_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
CP013849.1\|AUM91769.1\|2365822_2366344_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
CP013849.1\|AUM91758.1\|2354787_2356881_-\|sugar-transporter	unknown	unknown	gnl\|CDD\|226234
CP013849.1\|AUM91767.1\|2363228_2364635_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340904
CP013849.1\|AUM91770.1\|2366455_2368453_-\|2-enoate-reductase	unknown	unknown	gnl\|CDD\|239241

Protein	Function_ID	Function_description	E-value
CP013849.1\|AUM91773.1\|2371264_2372113_-\|phenazine-biosynthesis-protein-PhzF-family	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.39603e-61
CP013849.1\|AUM91754.1\|2348869_2350009_-\|3-dehydroquinate-synthase	gnl\|CDD\|341476	cd08197, DOIS, 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose. 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics. 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotics includes neomycin, kanamycin, gentamicin, and ribostamycin. They are important antibacterial agents. DOIS is a homolog of the dehydroquinate synthase which catalyzes the cyclization of 3-deoxy-D-arabino-heputulosonate-7-phosphate to dehydroquinate (DHQ) in the shikimate pathway.	1.73999e-153
CP013849.1\|AUM91755.1\|2350572_2352564_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.000529996
CP013849.1\|AUM91761.1\|2358782_2359220_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|182417	PRK10372, PRK10372, PTS ascorbate transporter subunit IIA.	4.73815e-38
CP013849.1\|AUM91762.1\|2359243_2359960_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	6.47741e-157
CP013849.1\|AUM91765.1\|2362628_2362898_+\|peptidase-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	5.99944e-08
CP013849.1\|AUM91766.1\|2362981_2363155_+\|metallopeptidase,-family-M24	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	7.33995e-13
CP013849.1\|AUM91768.1\|2364737_2365478_-\|SAM-dependent-methyltransferase	gnl\|CDD\|100107	cd02440, AdoMet_MTases, S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).	1.79931e-11
CP013849.1\|AUM91772.1\|2370076_2370946_-\|phenazine-biosynthesis-protein-PhzF	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.17736e-88
CP013849.1\|AUM91759.1\|2357092_2358457_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
CP013849.1\|AUM91757.1\|2354108_2354462_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
CP013849.1\|AUM91771.1\|2368560_2369358_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.47479e-15
CP013849.1\|AUM91763.1\|2360863_2361598_-\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.39268e-11
CP013849.1\|AUM91760.1\|2358469_2358754_-\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	1.57443e-28
CP013849.1\|AUM91756.1\|2352553_2353321_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.33605e-104
CP013849.1\|AUM91769.1\|2365822_2366344_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	1.23442e-25
CP013849.1\|AUM91758.1\|2354787_2356881_-\|sugar-transporter	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.34931e-56
CP013849.1\|AUM91767.1\|2363228_2364635_+\|MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.9059e-120
CP013849.1\|AUM91770.1\|2366455_2368453_-\|2-enoate-reductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0

>CP013849.1|AUM91763.1|2360863_2361598_-|transpeptidase-transglycosylase
MDKFRNMKKSHIALLVVMYMVLMGSLPRFTGWATIFSAIAVGGYFLKNKKDLKELTKKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKMMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEESKKKAEEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNESENVDNNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARSEGLSPCSVCNP
>CP013849.1|AUM91762.1|2359243_2359960_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVEALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>CP013849.1|AUM91761.1|2358782_2359220_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINNQVVEVNAEVKNWEEAVRLGGKLLEKDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>CP013849.1|AUM91760.1|2358469_2358754_-|PTS-maltose-transporter-subunit-IIBC
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEQLKK
>CP013849.1|AUM91759.1|2357092_2358457_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>CP013849.1|AUM91758.1|2354787_2356881_-|sugar-transporter
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGINLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFVTINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMEREELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDISDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKRDFIKLNEEAKDWEDAVRKSGEILMNNGCIKKSYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKINHMKALKELMSIMDQEDFISKVKNIKASSEIDSILYS
>CP013849.1|AUM91757.1|2354108_2354462_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>CP013849.1|AUM91756.1|2352553_2353321_-|multidrug-ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIIINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDEKVKSVAKYLEIEKVLNKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELVRGNDTRKEFFNKIIEVTSLLGGDDNNVF
>CP013849.1|AUM91755.1|2350572_2352564_-|ABC-transporter-permease
MYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIRSSGGSYVSRLMDFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVTETSIVGVISLIAGLIIGMGVSQGLSVFALKLFEVGINEYRFAVSTRAISKTILYFGIMFLLVMIFNIFVISKYKIIDLLTSGRKNENIKFKNKFIYSLSFLLCVVLLGFAYKSILKTGLKLREPMFKPSIAFVIVGTVLFFFTLAGVILYVVNKNKKIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILILSTGISFKNGLEEGVKIRAPFDASIIISNNSKKNNLEDVLDKINFKRSKDEKYVTCNEYLSGIKLESLLSITDKDYKDREVSFVKISDYNKILKLKGKKEINLNKDEILVMSTNNAVVKQANEKLKNSKKFNIKGKEYLVKNNKIIEENLATYLLADNVFTIVISDEFLYDYNKIVYSILNVMYSDKNREENNKKYSEINKNFVGGKYKNLNISYMGAFSKDDIYSHSKGGTTSILFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKVLKRIGANSKMIEKTIFLQTLIYFALPMILALVHSMIGIKVISDYIEVFTKIDISFSALITALIFSVVYAGYFYTTYTGYKNIVKSNI
>CP013849.1|AUM91754.1|2348869_2350009_-|3-dehydroquinate-synthase
MYMNLAQKINDDYYHPEVKLETNLLESSPIYLGCNIWRESLLEKMMDLNTDKFFLITDDVVYNLFGKELLEYMNRKASVKLIKLPSGEKHKNIKVFNDLMEDLFDNNVTKSSILISLGGGVVGNITGLAAALAFRGIRFFHIPTTFMSQTDSILSRKQGINSFYGKNMIGSYYTPLFNFIDTSFLTFDSERFIRGSFVETVKNGFIYNADFLNKLKSVIKNDFNVNQEGIFNLVKMSIESKLPIMKADPTEKGLAMILEYGHTVGHAIEKLSYGKLSHGESVSIGMMVAARISEKLGYLSKQDVKEHMDILSALKTPTKIPSNIKISDIINRIKLDNKKDINGIRFVVLQNIGKCINTDGSYMIKVPFNIINDAIEETC
>CP013849.1|AUM91764.1|2362454_2362634_-|hypothetical-protein
MHLIHCNNNKISGKNSIWFPRMLRVHLISSSELTSLATKVKGVLELSERFLTTVAFVEQ
>CP013849.1|AUM91765.1|2362628_2362898_+|peptidase-M24
MHLFINEIKLNDEIKSNLKENGALFIHPYNKIYKEVITEIGSSNKLDAFPAEQGRFIRPSFEPISSFGEHATIVTCILLMDNSFMIVTV
>CP013849.1|AUM91766.1|2362981_2363155_+|metallopeptidase,-family-M24
MNIHEAPAGFRWQYRPKETHRFEEGIVITDEPGIYIAGSHGIRIENELIVCKGENNG
>CP013849.1|AUM91767.1|2363228_2364635_+|MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFSKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSIESVSTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>CP013849.1|AUM91768.1|2364737_2365478_-|SAM-dependent-methyltransferase
MVNYYGSLCTTMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFESSIEEFSPKEKYDYIFITSGSFSLFLDEDSAFNVLVKIKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFRIKLYDFGELDKLILKAGFKRRHVFSDFNRRKSIDKNTETFLYECYI
>CP013849.1|AUM91769.1|2365822_2366344_+|DUF4825-domain-containing-protein
MKNKFKILVPLLLILSLNLIGCGVNSERKSKENVKNSSKVETYDLIKYKGAYIGDNSSVGSIIKNLPANEYSAGFSLQTSKEPYEITINYKANENLGEENYNKFWSDKKANKLLEKNAVVLLSLIPNAEIIKFNVDSIGEESYKYDKKNLEQKYGNLKDLFKDNDSLNKFLNN
>CP013849.1|AUM91770.1|2366455_2368453_-|2-enoate-reductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENSIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPGEEFEEKGRDIPEGIEAAKMLVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKNAVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAVRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLDVEIKLNVDVSKENIKEFGADEVLLATGSSPRTLTIEGADNVYSAEDVLMERKNVGEKVIVIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLIDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNKVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>CP013849.1|AUM91771.1|2368560_2369358_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIKVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKELKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>CP013849.1|AUM91772.1|2370076_2370946_-|phenazine-biosynthesis-protein-PhzF
MKVKAYTLNSFAKCIEGGNPAGVVINADDLSEDNMKKVAGIIGFSETAFVMNSDLADFKVRFFTPNEEVDICGHATIATFSTLLSQGRIEPGKYFQETKAGVLSVELKEDLSIMMNQNTPSYYETICKQEIADSLNITTAEMSEELPIQIVSTGLRDILIPIKNIDMVNAIKPNFEKVSRISSKYNTIGYHIFTLESLNGSNAYCRNLAPLYGIPEESATGTSNGALACYLFKYGKIKSDNTNHIVIEQGYSMEKPSEIIVSLITEGKEVIEIKVGGKALNLSEIEVEI
>CP013849.1|AUM91773.1|2371264_2372113_-|phenazine-biosynthesis-protein-PhzF-family
MEYFHVDVFSNEILYGNGLTVVFCNEELEDNLMLKLTQEFKQFETIFVRRIDNSIFNARIFTVDEELDFAGHPILGAAATIHSNIFRNEEDIAITFQLNQKTIIVNSKKIEEYYEVQMNQGKAEFLCEVSKEKRNKYVHALNLSEENLSEEFPMEVVSTGLPYLLVPLTSGIENAKIISSKFEEMLKEVGAKFAYIFDVNYIEGRTWDNQGNVEDVATGSAAGPLGAYLYKHNIFNVGHEIIINQGRFVGRPSKIKVSMSISEKEILVSGEVAILAKGTILL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP013849_4	4.1\|3192569\|25\|CP013849\|CRISPRCasFinder	3192569-3192593	25	MH598512	Bacillus phage Wes44, complete genome	8512-8536	4	0.84
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	MN694394	Marine virus AFVG_250M672, complete genome	9926-9957	5	0.844
CP013849_3	3.1\|2362401\|36\|CP013849\|CRISPRCasFinder	2362401-2362436	36	MK250029	Prevotella phage Lak-C1, complete genome	463569-463604	6	0.833
CP013849_3	3.1\|2362401\|36\|CP013849\|CRISPRCasFinder	2362401-2362436	36	MK250016	Prevotella phage Lak-A1, complete genome	498504-498539	6	0.833
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	MF288922	Bacillus phage Janet, complete genome	141740-141771	7	0.781
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP037428	Myroides odoratimimus strain G13 plasmid pFM-G13, complete sequence	28647-28678	8	0.75
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	MN694568	Marine virus AFVG_250M879, complete genome	47511-47542	8	0.75
CP013849_2	2.3\|2362052\|36\|CP013849\|CRT	2362052-2362087	36	MN694394	Marine virus AFVG_250M672, complete genome	9925-9960	9	0.75
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	253634-253665	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	176811-176842	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	85024-85055	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	303346-303377	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	70747-70778	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	303347-303378	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	187831-187862	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	302959-302990	9	0.719
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	AP014437	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S26-C121, * SEQUENCING IN PROGRESS *, 5 ordered pieces	5340-5371	9	0.719
CP013849_2	2.6\|2362052\|37\|CP013849\|CRISPRCasFinder	2362052-2362088	37	MN694394	Marine virus AFVG_250M672, complete genome	9925-9961	10	0.73
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	NC_019357	Shigella boydii plasmid pSB13, complete sequence	4416-4447	10	0.688
CP013849_2	2.8\|2362053\|32\|CP013849\|PILER-CR	2362053-2362084	32	MN856100	Bacteriophage sp. isolate 2, complete genome	108924-108955	10	0.688
CP013849_3	3.1\|2362401\|36\|CP013849\|CRISPRCasFinder	2362401-2362436	36	NC_001949	Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence	11489-11524	10	0.722

1. spacer 4.1|3192569|25|CP013849|CRISPRCasFinder matches to MH598512 (Bacillus phage Wes44, complete genome) position: , mismatch: 4, identity: 0.84

ttagttctaacaatattggttgtaa	CRISPR spacer
ctgattctaactatattggttgtaa	Protospacer
.*..******* *************

2. spacer 2.8|2362053|32|CP013849|PILER-CR matches to MN694394 (Marine virus AFVG_250M672, complete genome) position: , mismatch: 5, identity: 0.844

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
gttagggtcttcttttactgcacttatttctt	Protospacer
. ***************** ****** ****

3. spacer 3.1|2362401|36|CP013849|CRISPRCasFinder matches to MK250029 (Prevotella phage Lak-C1, complete genome) position: , mismatch: 6, identity: 0.833

tacaaatccaaaagaaattgatttaaatcaaataaa	CRISPR spacer
tagttatccaaaagaatttgattttaatcaaataac	Protospacer
**   *********** ******* **********

4. spacer 3.1|2362401|36|CP013849|CRISPRCasFinder matches to MK250016 (Prevotella phage Lak-A1, complete genome) position: , mismatch: 6, identity: 0.833

tacaaatccaaaagaaattgatttaaatcaaataaa	CRISPR spacer
tagttatccaaaagaatttgattttaatcaaataac	Protospacer
**   *********** ******* **********

5. spacer 2.8|2362053|32|CP013849|PILER-CR matches to MF288922 (Bacillus phage Janet, complete genome) position: , mismatch: 7, identity: 0.781

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
agtgatttcttcttctagttcacttaattctt	Protospacer
***..  *******.** *************

6. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP037428 (Myroides odoratimimus strain G13 plasmid pFM-G13, complete sequence) position: , mismatch: 8, identity: 0.75

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
ttctgtatcttcttttactttacttacttcta	Protospacer
  . * .*************.***** *****

7. spacer 2.8|2362053|32|CP013849|PILER-CR matches to MN694568 (Marine virus AFVG_250M879, complete genome) position: , mismatch: 8, identity: 0.75

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
tttattatcttctttaacttcatttaattctt	Protospacer
  **  .******** ******.********

8. spacer 2.3|2362052|36|CP013849|CRT matches to MN694394 (Marine virus AFVG_250M672, complete genome) position: , mismatch: 9, identity: 0.75

tagtagggtcttcttttacttcacttaattctaaga	CRISPR spacer
agttagggtcttcttttactgcacttatttcttgat	Protospacer
 . ***************** ****** **** ..

9. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

10. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

11. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

12. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

13. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

14. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

15. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

16. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
taaaagttcttcgtttacttctcttaattccg	Protospacer
 . *.* ***** ******** ********..

17. spacer 2.8|2362053|32|CP013849|PILER-CR matches to AP014437 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C27-MedDCM-OCT-S26-C121, *** SEQUENCING IN PROGRESS ***, 5 ordered pieces) position: , mismatch: 9, identity: 0.719

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
aagtatattttcttttactttacctaattcta	Protospacer
*.  . .*.***********.**.********

18. spacer 2.6|2362052|37|CP013849|CRISPRCasFinder matches to MN694394 (Marine virus AFVG_250M672, complete genome) position: , mismatch: 10, identity: 0.73

tagtagggtcttcttttacttcacttaattctaagat	CRISPR spacer
agttagggtcttcttttactgcacttatttcttgatc	Protospacer
 . ***************** ****** **** .. .

19. spacer 2.8|2362053|32|CP013849|PILER-CR matches to NC_019357 (Shigella boydii plasmid pSB13, complete sequence) position: , mismatch: 10, identity: 0.688

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
atctatatcttcttttacttcttttaattcac	Protospacer
* . . .************** .*******

20. spacer 2.8|2362053|32|CP013849|PILER-CR matches to MN856100 (Bacteriophage sp. isolate 2, complete genome) position: , mismatch: 10, identity: 0.688

agtagggtcttcttttacttcacttaattcta	CRISPR spacer
tgcgtatgcttcttttactttatttaattctg	Protospacer
 *.. .  ************.*.********.

21. spacer 3.1|2362401|36|CP013849|CRISPRCasFinder matches to NC_001949 (Lactococcus lactis DPC3147 plasmid pMRC01, complete sequence) position: , mismatch: 10, identity: 0.722

tacaaatccaaaagaaattgatttaaatcaaataaa	CRISPR spacer
cgaatggaaaaaagaaactgatttatatcaaataaa	Protospacer
.. * .   ********.******* **********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

597928 : 607002

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM90218.1\|597928_600157_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.5e-107	34.7
AUM93189.1\|600805_601015_+	hypothetical protein	H7BUU1	unidentified_phage	1.5e-12	57.1
AUM90219.1\|601896_602244_+	hypothetical protein	A0A0A7RTL9	Clostridium_phage	4.9e-29	59.6
AUM90220.1\|602292_602412_-	hypothetical protein	NA	NA	NA	NA
AUM90221.1\|602929_603739_+	hypothetical protein	A0A2I2L551	Orpheovirus	2.3e-45	41.0
AUM90222.1\|604353_605730_+	phosphate starvation-inducible protein PhoH	A0A141HS37	Bacillus_phage	1.8e-106	44.3
AUM90223.1\|605997_607002_+	exopolysaccharide biosynthesis protein	A0A1P8CWN9	Bacillus_phage	5.6e-09	30.7

DBSCAN-SWA_2

1739959 : 1747024

uncultured_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM91226.1\|1739959_1740904_-	decarboxylase	A0A1B0RXM1	Streptococcus_phage	1.5e-11	28.9
AUM91227.1\|1741526_1742522_+	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUM91228.1\|1742638_1743400_+	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUM91229.1\|1743417_1743849_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	8.8e-12	31.6
AUM91230.1\|1743850_1744516_+	7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	1.3e-38	44.1
AUM91231.1\|1744519_1745110_+	type I GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	1.6e-43	52.3
AUM91232.1\|1745293_1745953_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.7e-59	51.2
AUM91233.1\|1746067_1747024_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.7e-16	33.5

DBSCAN-SWA_3

2090330 : 2099980

Clostridium_phage(75.0%)

integrase

attL 2083266:2083281|attR 2104319:2104334

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2083266:2083281	attL	NA	NA	NA	NA
AUM93227.1\|2090330_2090840_-	hypothetical protein	A0A0A7RUC3	Clostridium_phage	1.3e-43	55.0
AUM91533.1\|2091228_2091585_-	Holliday junction resolvase	A0A0A7S133	Clostridium_phage	6.3e-48	74.4
AUM91534.1\|2091755_2092124_-	hypothetical protein	A0A0A7RVR5	Clostridium_phage	1.2e-20	41.2
AUM91535.1\|2092471_2092807_-	hypothetical protein	NA	NA	NA	NA
AUM91536.1\|2092932_2093211_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
AUM91537.1\|2093214_2093418_-	hypothetical protein	NA	NA	NA	NA
AUM91538.1\|2093427_2094195_-	MerR family transcriptional regulator	M9Q1J4	Clostridium_phage	1.2e-51	47.7
AUM91539.1\|2094127_2094907_-	hypothetical protein	A0A2P1JTY8	Anoxybacillus_phage	1.4e-47	46.7
AUM91540.1\|2094929_2095214_-	hypothetical protein	NA	NA	NA	NA
AUM91541.1\|2095215_2095764_-	recombinase	B6SBX8	Clostridium_virus	4.2e-51	61.9
AUM91542.1\|2095768_2096263_-	hypothetical protein	A0A0A7S0G6	Clostridium_phage	2.0e-39	52.5
AUM91543.1\|2096259_2096928_-	hypothetical protein	A0A0A7RVQ9	Clostridium_phage	5.2e-88	82.6
AUM91544.1\|2096940_2097231_-	histidine kinase	NA	NA	NA	NA
AUM91545.1\|2097386_2097602_-	transcriptional regulator	A0A0A7S0N3	Clostridium_phage	6.5e-08	46.5
AUM91546.1\|2097781_2098270_+	hypothetical protein	A0A0A7RTU8	Clostridium_phage	2.1e-38	75.2
AUM91547.1\|2098294_2098759_+	hypothetical protein	A0A0A7RVV2	Clostridium_phage	4.5e-38	53.3
AUM91548.1\|2098909_2099980_+\|integrase	site-specific integrase	B3GVW7	Streptococcus_phage	1.6e-30	32.0
2104319:2104334	attR	NA	NA	NA	NA

DBSCAN-SWA_4

3033180 : 3042663

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM92367.1\|3033180_3034680_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.0e-67	45.6
AUM92368.1\|3034893_3035511_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.1e-26	40.3
AUM92369.1\|3035638_3036634_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	9.9e-67	43.7
AUM92370.1\|3036694_3038143_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.2e-58	35.1
AUM92371.1\|3038234_3038939_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	6.0e-42	42.1
AUM92372.1\|3038938_3039418_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.8e-27	49.4
AUM92373.1\|3039937_3040072_+	hypothetical protein	NA	NA	NA	NA
AUM92374.1\|3040092_3042663_-	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	1.3e-09	32.4

DBSCAN-SWA_5

3179324 : 3211535

Clostridium_phage(76.92%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM92497.1\|3179324_3181952_-	DNA polymerase I	F8WQ35	Bacillus_phage	4.2e-64	35.4
AUM92498.1\|3181969_3183094_-	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-31	30.1
AUM92499.1\|3183492_3184272_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	2.3e-87	62.3
AUM92500.1\|3184418_3184613_-	hypothetical protein	NA	NA	NA	NA
AUM92501.1\|3184631_3184886_-	hypothetical protein	A0A0A7RTX0	Clostridium_phage	4.8e-26	70.9
AUM92502.1\|3185038_3185827_-	hypothetical protein	A0A0A7RU33	Clostridium_phage	6.7e-26	33.8
AUM92503.1\|3185859_3186684_-	carbohydrate-binding protein	A0A0A7RU33	Clostridium_phage	5.6e-15	28.4
AUM92504.1\|3186749_3187517_-	hypothetical protein	NA	NA	NA	NA
AUM92505.1\|3187568_3188348_-	hypothetical protein	NA	NA	NA	NA
AUM92506.1\|3188350_3189268_-	hypothetical protein	NA	NA	NA	NA
AUM92507.1\|3189300_3190386_-	signal peptidase II	A0A0A7RU66	Clostridium_phage	7.9e-142	70.1
AUM92508.1\|3190397_3191396_-	hypothetical protein	A0A0A7RW91	Clostridium_phage	5.5e-142	72.9
AUM92509.1\|3191407_3191683_-	hypothetical protein	NA	NA	NA	NA
AUM92510.1\|3191685_3193707_-	hypothetical protein	A0A0A7RU09	Clostridium_phage	2.5e-56	48.5
AUM92511.1\|3193718_3195227_-	hypothetical protein	A0A0A7RU28	Clostridium_phage	5.5e-93	37.7
AUM92512.1\|3195240_3196236_-	hypothetical protein	A0A0A7RU61	Clostridium_phage	3.0e-111	60.7
AUM92513.1\|3196237_3197578_-	hypothetical protein	A0A0A7RW86	Clostridium_phage	2.1e-75	74.6
AUM92514.1\|3197592_3197934_-	hypothetical protein	A0A0A7S0S4	Clostridium_phage	2.1e-16	55.7
AUM92515.1\|3197946_3199032_-	hypothetical protein	NA	NA	NA	NA
AUM92516.1\|3199018_3199453_-	hypothetical protein	NA	NA	NA	NA
AUM92517.1\|3199465_3201007_-	hypothetical protein	A0A0A7RU22	Clostridium_phage	5.8e-05	42.4
AUM93255.1\|3201170_3201338_-	hypothetical protein	A0A0A7RW80	Clostridium_phage	1.9e-15	70.4
AUM92518.1\|3201372_3201789_-	esterase	A0A0A7S0S0	Clostridium_phage	9.0e-46	71.2
AUM92519.1\|3201803_3202691_-	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	5.9e-119	74.1
AUM92520.1\|3202695_3203115_-	hypothetical protein	A0A0A7RU17	Clostridium_phage	2.1e-58	74.1
AUM92521.1\|3203120_3203468_-	hypothetical protein	A0A0A7RU51	Clostridium_phage	3.6e-32	58.9
AUM92522.1\|3203472_3203838_-	hypothetical protein	A0A0A7RW73	Clostridium_phage	2.2e-32	57.0
AUM92523.1\|3203837_3204122_-	hypothetical protein	A0A0A7S0R4	Clostridium_phage	2.7e-25	61.2
AUM92524.1\|3204626_3205148_-	hypothetical protein	A0A0A7RVS1	Clostridium_phage	2.4e-35	50.0
AUM92525.1\|3205261_3205582_-	hypothetical protein	NA	NA	NA	NA
AUM92526.1\|3205638_3206487_-	DNA replication protein	A0A2K9V3L7	Faecalibacterium_phage	1.0e-32	34.8
AUM92527.1\|3206428_3207334_-	hypothetical protein	A8ASN4	Listeria_phage	2.7e-39	39.9
AUM92528.1\|3207427_3207661_-	transcriptional regulator	NA	NA	NA	NA
AUM92529.1\|3207701_3207911_-	transcriptional regulator	NA	NA	NA	NA
AUM92530.1\|3208102_3208513_+	transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
AUM92531.1\|3208814_3208964_+	hypothetical protein	NA	NA	NA	NA
AUM92532.1\|3210047_3211535_+	membrane-bound O-acyltransferase family protein	A0A125RNP0	Pseudomonas_phage	2.8e-65	37.8

DBSCAN-SWA_6

3344525 : 3390098

Clostridium_phage(42.86%)

capsid,head,terminase,tail,tRNA,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM92647.1\|3344525_3347171_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.4e-176	43.2
AUM92648.1\|3347191_3347698_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AUM92649.1\|3348151_3348907_-	bacitracin ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-17	29.4
AUM92650.1\|3351832_3352861_+	nitrate ABC transporter substrate-binding protein	NA	NA	NA	NA
AUM92651.1\|3353232_3357525_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
AUM92652.1\|3357846_3358608_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.0e-31	39.5
AUM92653.1\|3358604_3359408_+	sulfonate ABC transporter permease	NA	NA	NA	NA
AUM92654.1\|3359550_3359898_+	hypothetical protein	NA	NA	NA	NA
AUM92655.1\|3360019_3361195_-	transglutaminase	NA	NA	NA	NA
AUM92656.1\|3361219_3362155_-	recombination regulator RecX	NA	NA	NA	NA
AUM92657.1\|3362176_3363406_-	peptidase M16	G3MBJ8	Bacillus_virus	3.4e-32	28.5
AUM92658.1\|3363626_3364130_+	transporter	E7DN70	Pneumococcus_phage	2.2e-14	40.8
AUM92659.1\|3364327_3364912_+	flavin reductase	NA	NA	NA	NA
AUM92660.1\|3365302_3365536_+	transcriptional regulator	A0A0A7RUG5	Clostridium_phage	5.1e-22	68.8
AUM92661.1\|3365609_3365894_+	transcriptional regulator	A0A0A7S0F1	Clostridium_phage	4.9e-35	83.7
AUM92662.1\|3365962_3366289_-	hypothetical protein	NA	NA	NA	NA
AUM92663.1\|3366275_3367145_-	heat-shock protein Hsp70	Q0SPH6	Clostridium_phage	2.1e-28	31.5
AUM92664.1\|3367285_3368002_-	hypothetical protein	NA	NA	NA	NA
AUM92665.1\|3368747_3368927_+	toxin HicA	NA	NA	NA	NA
AUM92666.1\|3368985_3369399_+	HicB family protein	A0A090DBV2	Clostridium_phage	4.9e-20	39.6
AUM92667.1\|3369423_3370194_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	5.5e-89	65.2
AUM92668.1\|3370236_3370431_-	hypothetical protein	NA	NA	NA	NA
AUM92669.1\|3370434_3370713_-	hypothetical protein	A0A2H4J1Q4	uncultured_Caudovirales_phage	8.7e-21	53.8
AUM92670.1\|3370784_3370931_-	polysulfide reductase	A0A0A7RTH5	Clostridium_phage	1.4e-09	64.4
AUM92671.1\|3370930_3371131_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
AUM92672.1\|3371141_3373892_-	hypothetical protein	I1TJW8	Clostridium_phage	8.8e-73	34.5
AUM92673.1\|3373891_3375256_-	DUF2479 domain-containing protein	A0A0A7S181	Clostridium_phage	6.3e-88	77.9
AUM92674.1\|3375272_3376940_-	endopeptidase	A0A0A7RUI9	Clostridium_phage	3.4e-75	41.5
AUM92675.1\|3376939_3377617_-\|tail	phage tail protein	A0A0A7RWN1	Clostridium_phage	3.1e-43	41.6
AUM92676.1\|3377616_3380286_-\|tail	phage tail tape measure protein	A0A0H4TEZ5	Erysipelothrix_phage	1.8e-86	54.5
AUM92677.1\|3380517_3381003_-	hypothetical protein	A0A0K2CP90	Brevibacillus_phage	5.4e-10	34.8
AUM92678.1\|3381064_3381658_-	hypothetical protein	A0A1J1J8Y5	Escherichia_phage	1.6e-64	60.9
AUM92679.1\|3381657_3382002_-	AP endonuclease	A0A1J1JCF3	Escherichia_phage	9.5e-17	46.7
AUM92680.1\|3382001_3382511_-	hypothetical protein	NA	NA	NA	NA
AUM92681.1\|3382527_3382896_-	ABC transporter ATPase	A0A2H4J4N9	uncultured_Caudovirales_phage	1.7e-43	73.0
AUM92682.1\|3382899_3383331_-	chloramphenicol resistance protein	A0A0A8WJ92	Clostridium_phage	5.8e-40	56.7
AUM92683.1\|3383317_3383497_-	hypothetical protein	NA	NA	NA	NA
AUM92684.1\|3383493_3383838_-\|capsid	capsid protein	F6K8R4	Clostridium_phage	1.2e-16	44.2
AUM92685.1\|3383837_3384248_-	hypothetical protein	F6K8R3	Clostridium_phage	1.3e-20	40.8
AUM92686.1\|3384249_3384516_-	hypothetical protein	NA	NA	NA	NA
AUM92687.1\|3384740_3385631_-\|capsid	capsid protein	A0A0H3U2U7	Staphylococcus_phage	3.4e-58	42.6
AUM92688.1\|3385646_3386240_-	hypothetical protein	A0A1L2K2N1	Aeribacillus_phage	3.8e-21	38.9
AUM92689.1\|3386299_3387031_-\|head	phage head morphogenesis protein	NA	NA	NA	NA
AUM92690.1\|3387020_3388298_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	4.3e-115	52.8
AUM92691.1\|3388301_3390098_-\|terminase	terminase	A0A1V0DZW7	Clostridioides_phage	6.1e-107	36.4

DBSCAN-SWA_7

3394996 : 3405283

Clostridium_phage(44.44%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AUM92696.1\|3394996_3395581_-	molybdopterin-guanine dinucleotide biosynthesis protein A	A0A2D1GQA7	Lysinibacillus_phage	1.6e-32	44.2
AUM92697.1\|3395630_3396614_-	hypothetical protein	NA	NA	NA	NA
AUM92698.1\|3396732_3396966_-	hypothetical protein	NA	NA	NA	NA
AUM92699.1\|3397022_3397433_-	single-stranded DNA-binding protein	Q8SBL5	Clostridium_phage	2.2e-28	47.5
AUM92700.1\|3397436_3398063_-	metal-dependent phosphohydrolase	A0A2H4J8L1	uncultured_Caudovirales_phage	8.0e-38	41.2
AUM92701.1\|3398075_3398789_-	MBL fold metallo-hydrolase	A8ATK9	Listeria_phage	4.5e-45	41.9
AUM92702.1\|3398788_3399709_-	hypothetical protein	A0A0A7RUP3	Clostridium_phage	4.6e-66	52.8
AUM92703.1\|3399710_3401648_-	acyl-CoA dehydrogenase	A8ATK7	Listeria_phage	6.6e-75	36.1
AUM92704.1\|3401650_3401803_-	flavodoxin	NA	NA	NA	NA
AUM92705.1\|3401799_3402117_-	hypothetical protein	A0A0A7S0N7	Clostridium_phage	5.1e-09	39.4
AUM92706.1\|3402164_3402428_-	hypothetical protein	NA	NA	NA	NA
AUM92707.1\|3402489_3402633_-	sporulation protein Spo0E	NA	NA	NA	NA
AUM92708.1\|3402941_3403157_-	hypothetical protein	NA	NA	NA	NA
AUM92709.1\|3403371_3403755_+	transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	4.2e-05	40.6
AUM92710.1\|3403756_3405283_+	hypothetical protein	A0A1L2BY67	Clostridium_phage	3.1e-83	38.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP013849

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection